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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SOX4

Z-value: 1.43

Motif logo

Transcription factors associated with SOX4

Gene Symbol	Gene ID	Gene Info
SOX4 Ensembl NCBI GeneCards UniProt	ENSG00000124766.4	SOX4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
SOX4	chr6_21731767_21731918	137771	0.053893	0.90	1.0e-03	Click!
SOX4	chr6_21615827_21615978	21831	0.294401	0.85	4.0e-03	Click!
SOX4	chr6_21664794_21664945	70798	0.140629	0.82	7.3e-03	Click!
SOX4	chr6_21605761_21605912	11765	0.325020	0.81	8.0e-03	Click!
SOX4	chr6_21599354_21599505	5358	0.360002	0.80	9.2e-03	Click!

Activity of the SOX4 motif across conditions

Conditions sorted by the z-value of the SOX4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr22_44704706_44704857	0.63	KIAA1644	KIAA1644	3950	0.31
chr14_105147633_105147901	0.62	ENSG00000265291	.	3681	0.16
chr5_14205387_14205588	0.58	TRIO	trio Rho guanine nucleotide exchange factor	21580	0.29
chr3_187627904_187628178	0.58	BCL6	B-cell CLL/lymphoma 6	164526	0.04
chr4_15681074_15681472	0.58	FBXL5	F-box and leucine-rich repeat protein 5	1904	0.29
chr11_69910489_69910640	0.57	ANO1-AS2	ANO1 antisense RNA 2 (head to head)	10890	0.16
chr6_134616962_134617231	0.56	ENSG00000201309	.	12866	0.2
chr2_208121455_208121606	0.52	AC007879.5		2554	0.31
chr1_94188465_94188866	0.52	BCAR3	breast cancer anti-estrogen resistance 3	41280	0.16
chr3_45515586_45515737	0.51	LARS2-AS1	LARS2 antisense RNA 1	35376	0.18
chr20_4022392_4022773	0.50	RNF24	ring finger protein 24	26353	0.17
chr2_172654761_172655200	0.49	AC068039.4		24988	0.19
chr3_151693616_151693983	0.49	RP11-454C18.2		47836	0.17
chr3_99615369_99615520	0.47	FILIP1L	filamin A interacting protein 1-like	20398	0.23
chr9_97567295_97567893	0.47	ENSG00000252153	.	4650	0.2
chr1_27098788_27098939	0.47	ARID1A	AT rich interactive domain 1A (SWI-like)	592	0.64
chr1_197751092_197751472	0.47	DENND1B	DENN/MADD domain containing 1B	6519	0.24
chr4_23946972_23947800	0.47	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	55686	0.17
chr7_12758629_12758982	0.46	ENSG00000199470	.	18291	0.22
chr6_119491995_119492146	0.46	FAM184A	family with sequence similarity 184, member A	21518	0.24
chr12_66289441_66289878	0.45	RP11-366L20.2	Uncharacterized protein	13712	0.17
chr6_40926485_40926636	0.45	UNC5CL	unc-5 homolog C (C. elegans)-like	76314	0.08
chr10_75665699_75666012	0.45	PLAU	plasminogen activator, urokinase	3080	0.18
chr1_154153362_154154055	0.45	TPM3	tropomyosin 3	1887	0.18
chr8_32093522_32093809	0.44	NRG1-IT2	NRG1 intronic transcript 2 (non-protein coding)	15221	0.2
chr7_127525858_127526009	0.44	SND1	staphylococcal nuclease and tudor domain containing 1	2032	0.45
chr11_36522618_36522914	0.44	TRAF6	TNF receptor-associated factor 6, E3 ubiquitin protein ligase	9040	0.22
chr1_202334150_202334335	0.43	PPP1R12B	protein phosphatase 1, regulatory subunit 12B	16386	0.17
chr3_149091203_149091498	0.43	TM4SF1	transmembrane 4 L six family member 1	2149	0.29
chr14_103838670_103838952	0.43	MARK3	MAP/microtubule affinity-regulating kinase 3	12918	0.15
chr7_2150324_2150795	0.43	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	1323	0.57
chr11_19402252_19402403	0.43	NAV2-IT1	NAV2 intronic transcript 1 (non-protein coding)	296	0.9
chr12_32268115_32268884	0.43	RP11-843B15.2		8037	0.23
chr4_146802214_146802365	0.42	RP11-181K12.2		48019	0.15
chr8_124643142_124643293	0.42	CTD-2552K11.2		16752	0.17
chr12_25920871_25921133	0.42	ENSG00000222950	.	11501	0.28
chr20_4346497_4346648	0.41	ADRA1D	adrenoceptor alpha 1D	116851	0.06
chr10_30072409_30072560	0.41	SVIL	supervillin	47751	0.17
chr7_116483262_116484087	0.41	CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	18853	0.19
chr3_81634188_81634341	0.41	ENSG00000222389	.	75637	0.13
chr1_167745053_167745204	0.41	MPZL1	myelin protein zero-like 1	10321	0.23
chr3_100322115_100322506	0.41	GPR128	G protein-coupled receptor 128	6123	0.25
chr3_172274970_172275468	0.40	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	33922	0.18
chr14_45667845_45667996	0.40	FANCM	Fanconi anemia, complementation group M	2263	0.31
chr3_45137145_45137443	0.40	CDCP1	CUB domain containing protein 1	50620	0.11
chr16_66614095_66614456	0.40	RP11-403P17.2		344	0.69
chr3_112964527_112964768	0.40	BOC	BOC cell adhesion associated, oncogene regulated	29449	0.19
chr12_51328994_51329173	0.40	ENSG00000199740	.	4726	0.16
chr15_49966918_49967069	0.40	RP11-353B9.1		22657	0.2
chr8_70745558_70745875	0.40	SLCO5A1	solute carrier organic anion transporter family, member 5A1	91	0.91
chr3_156872753_156873290	0.38	ENSG00000201778	.	1684	0.29
chr15_36721035_36721186	0.38	C15orf41	chromosome 15 open reading frame 41	150702	0.05
chr1_31870789_31870940	0.38	SERINC2	serine incorporator 2	11548	0.15
chr10_74498015_74498488	0.38	ENSG00000266719	.	17464	0.16
chr9_14205951_14206102	0.37	NFIB	nuclear factor I/B	25229	0.27
chr21_39856448_39856602	0.37	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog	13820	0.3
chr2_47063884_47064035	0.37	AC016722.3		16676	0.14
chr3_124602395_124602546	0.37	ITGB5	integrin, beta 5	3674	0.27
chr2_173205766_173206054	0.37	ITGA6	integrin, alpha 6	86172	0.08
chr11_69988196_69988347	0.37	ANO1	anoctamin 1, calcium activated chloride channel	571	0.71
chr5_14261499_14261650	0.37	TRIO	trio Rho guanine nucleotide exchange factor	29512	0.26
chr1_120330313_120330596	0.37	HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	18926	0.18
chr1_214492542_214492693	0.36	SMYD2	SET and MYND domain containing 2	11703	0.26
chr4_169449939_169450239	0.36	PALLD	palladin, cytoskeletal associated protein	17370	0.21
chr18_9611497_9611648	0.36	PPP4R1	protein phosphatase 4, regulatory subunit 1	2713	0.23
chr9_35518799_35519162	0.36	RUSC2	RUN and SH3 domain containing 2	19649	0.14
chr15_58624990_58625276	0.36	ALDH1A2	aldehyde dehydrogenase 1 family, member A2	53671	0.14
chr20_1791307_1791458	0.36	SIRPA	signal-regulatory protein alpha	83772	0.08
chr14_73025255_73025432	0.36	RGS6	regulator of G-protein signaling 6	98966	0.09
chr18_45549628_45549779	0.36	ZBTB7C	zinc finger and BTB domain containing 7C	17791	0.26
chr5_77836656_77836905	0.35	LHFPL2	lipoma HMGIC fusion partner-like 2	8194	0.31
chr10_73292337_73292498	0.35	CDH23-AS1	CDH23 antisense RNA 1	20787	0.22
chr15_82439494_82439645	0.35	ENSG00000212170	.	27157	0.18
chr7_98866139_98866290	0.35	ARPC1A	actin related protein 2/3 complex, subunit 1A, 41kDa	57307	0.1
chr5_173958937_173959224	0.35	MSX2	msh homeobox 2	192456	0.03
chr3_149224282_149224576	0.35	ENSG00000252581	.	18989	0.18
chr4_99352509_99352759	0.35	RAP1GDS1	RAP1, GTP-GDP dissociation stimulator 1	52324	0.15
chr12_66270857_66271189	0.35	RP11-366L20.2	Uncharacterized protein	4335	0.21
chr2_28182385_28182785	0.35	ENSG00000265321	.	36649	0.16
chr20_16536753_16536975	0.35	KIF16B	kinesin family member 16B	17214	0.26
chr16_68774771_68774922	0.35	ENSG00000200558	.	1537	0.33
chr10_54203972_54204123	0.35	RP11-556E13.1		116818	0.06
chr2_118943233_118943804	0.34	INSIG2	insulin induced gene 2	97468	0.08
chr12_32655690_32655927	0.34	FGD4	FYVE, RhoGEF and PH domain containing 4	657	0.77
chr18_73368027_73368346	0.34	SMIM21	small integral membrane protein 21	228528	0.02
chr5_158521710_158521861	0.34	EBF1	early B-cell factor 1	4916	0.28
chr5_95593400_95593666	0.34	ENSG00000206997	.	47602	0.18
chr2_45686179_45686586	0.34	SRBD1	S1 RNA binding domain 1	108772	0.07
chr9_124968957_124969108	0.34	LHX6	LIM homeobox 6	7140	0.15
chr11_36383085_36383430	0.34	PRR5L	proline rich 5 like	401	0.87
chr10_24672477_24672647	0.34	KIAA1217	KIAA1217	65800	0.13
chr9_80014114_80014265	0.34	VPS13A	vacuolar protein sorting 13 homolog A (S. cerevisiae)	6695	0.29
chr6_72188105_72188315	0.34	ENSG00000212099	.	60469	0.12
chr5_93136970_93137121	0.34	RP11-185E12.2		59699	0.12
chr4_141057015_141057166	0.34	RP11-392B6.1		7921	0.23
chr14_68608308_68608459	0.34	ENSG00000244677	.	8242	0.23
chr2_6558571_6558722	0.34	AC017076.5		415016	0.01
chr15_63667041_63667498	0.33	CA12	carbonic anhydrase XII	6765	0.28
chr3_37905725_37905876	0.33	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like	2135	0.29
chr1_82691616_82691767	0.33	LPHN2	latrophilin 2	246118	0.02
chr7_80548768_80548919	0.33	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	176	0.98
chr17_15867016_15867167	0.33	ADORA2B	adenosine A2b receptor	18860	0.15
chr12_66192419_66192570	0.33	HMGA2	high mobility group AT-hook 2	25417	0.2
chr1_85312638_85312919	0.33	LPAR3	lysophosphatidic acid receptor 3	19064	0.22
chr3_159579440_159579591	0.33	SCHIP1	schwannomin interacting protein 1	8787	0.21
chr17_43248964_43249426	0.33	RP13-890H12.2		244	0.85
chr5_149012489_149012692	0.33	ENSG00000222213	.	26286	0.13
chr8_69244650_69244960	0.33	RP11-664D7.4	HCG1787533; Uncharacterized protein	1079	0.45
chr5_56737339_56737490	0.33	ENSG00000264748	.	40316	0.15
chr1_65640208_65640421	0.33	AK4	adenylate kinase 4	26428	0.2
chr7_27173527_27173922	0.33	HOXA4	homeobox A4	3306	0.08
chr1_41290558_41290709	0.33	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4	7696	0.15
chr10_94803087_94803238	0.32	RP11-348J12.2		17021	0.17
chr5_119723794_119723945	0.32	ENSG00000251975	.	50521	0.17
chr10_62190055_62190299	0.32	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	40689	0.22
chr7_23398587_23399002	0.32	ENSG00000212264	.	37271	0.15
chr3_30543799_30543950	0.32	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	104120	0.08
chr1_16158366_16158517	0.32	RP11-169K16.9		3914	0.18
chr6_89578019_89578170	0.32	RNGTT	RNA guanylyltransferase and 5'-phosphatase	95186	0.07
chr18_72936572_72937273	0.32	TSHZ1	teashirt zinc finger homeobox 1	3909	0.29
chr5_33031909_33032060	0.32	AC026703.1		243039	0.02
chr4_40329561_40329827	0.32	CHRNA9	cholinergic receptor, nicotinic, alpha 9 (neuronal)	7652	0.23
chr13_49687455_49688205	0.32	FNDC3A	fibronectin type III domain containing 3A	3381	0.28
chr3_99782870_99783025	0.32	FILIP1L	filamin A interacting protein 1-like	50410	0.13
chr21_45232400_45232551	0.32	AP001053.11		27	0.97
chr10_32438147_32438298	0.32	ENSG00000252482	.	24390	0.2
chr5_78199157_78199308	0.32	ARSB	arylsulfatase B	82376	0.1
chr4_159532420_159532571	0.31	C4orf46	chromosome 4 open reading frame 46	60549	0.1
chr9_94579747_94580327	0.31	ROR2	receptor tyrosine kinase-like orphan receptor 2	131125	0.05
chr2_217529680_217529831	0.31	IGFBP2	insulin-like growth factor binding protein 2, 36kDa	4299	0.2
chr15_44206044_44206195	0.31	FRMD5	FERM domain containing 5	5581	0.19
chr1_204289207_204289358	0.31	PLEKHA6	pleckstrin homology domain containing, family A member 6	39762	0.12
chr6_112204135_112204286	0.31	FYN	FYN oncogene related to SRC, FGR, YES	9555	0.29
chr1_172466362_172466630	0.31	SUCO	SUN domain containing ossification factor	34993	0.15
chr6_138913719_138913963	0.31	NHSL1	NHS-like 1	20164	0.24
chr3_11806556_11806771	0.31	VGLL4	vestigial like 4 (Drosophila)	44443	0.17
chr2_67791651_67791912	0.31	ETAA1	Ewing tumor-associated antigen 1	167330	0.04
chr3_159554251_159554402	0.31	SCHIP1	schwannomin interacting protein 1	3324	0.23
chr5_132175450_132175601	0.31	ENSG00000201274	.	8744	0.11
chr3_45686706_45687144	0.31	LIMD1-AS1	LIMD1 antisense RNA 1	43449	0.12
chr15_75474383_75474534	0.31	C15orf39	chromosome 15 open reading frame 39	13526	0.13
chr15_50697752_50697931	0.30	USP8	ubiquitin specific peptidase 8	18736	0.14
chr2_192031188_192031339	0.30	STAT4	signal transducer and activator of transcription 4	14941	0.22
chr1_230699462_230699613	0.30	COG2	component of oligomeric golgi complex 2	78701	0.09
chr11_10610385_10610563	0.30	MRVI1-AS1	MRVI1 antisense RNA 1	4270	0.2
chr7_141565022_141565323	0.30	OR9A3P	olfactory receptor, family 9, subfamily A, member 3 pseudogene	2512	0.17
chr8_28570826_28570977	0.30	EXTL3	exostosin-like glycosyltransferase 3	3026	0.25
chr15_92536686_92536888	0.30	SLCO3A1	solute carrier organic anion transporter family, member 3A1	139436	0.05
chr4_184096914_184097065	0.30	ENSG00000252048	.	1095	0.48
chr16_8818593_8818759	0.30	ABAT	4-aminobutyrate aminotransferase	4100	0.19
chr17_29578153_29578304	0.30	OMG	oligodendrocyte myelin glycoprotein	46201	0.1
chr9_12859223_12859508	0.30	ENSG00000222658	.	25955	0.2
chr6_35568601_35569436	0.30	ENSG00000212579	.	50577	0.1
chr16_85387994_85388222	0.29	RP11-680G10.1	Uncharacterized protein	2961	0.32
chr1_165831252_165831403	0.29	UCK2	uridine-cytidine kinase 2	33480	0.15
chr7_5258466_5258734	0.29	WIPI2	WD repeat domain, phosphoinositide interacting 2	4700	0.2
chr6_126362121_126362442	0.29	TRMT11	tRNA methyltransferase 11 homolog (S. cerevisiae)	34293	0.18
chr8_21754699_21754946	0.29	DOK2	docking protein 2, 56kDa	16352	0.18
chr14_85910841_85910992	0.29	RP11-497E19.2	Uncharacterized protein	84027	0.1
chr16_72910739_72911399	0.29	ENSG00000251868	.	55178	0.12
chr2_47243068_47243412	0.29	AC093732.1		24423	0.16
chr6_17933356_17933507	0.29	KIF13A	kinesin family member 13A	54263	0.15
chr16_57412060_57412211	0.29	CX3CL1	chemokine (C-X3-C motif) ligand 1	1251	0.37
chr1_178091189_178091340	0.29	RASAL2	RAS protein activator like 2	27988	0.26
chr11_46526688_46526839	0.29	ENSG00000265014	.	53324	0.11
chr7_42277998_42278286	0.29	GLI3	GLI family zinc finger 3	1484	0.59
chr4_15691432_15691583	0.29	FAM200B	family with sequence similarity 200, member B	8078	0.18
chr6_123033646_123033911	0.28	PKIB	protein kinase (cAMP-dependent, catalytic) inhibitor beta	4928	0.25
chr1_151432183_151432391	0.28	POGZ	pogo transposable element with ZNF domain	346	0.81
chr3_112932086_112932237	0.28	BOC	BOC cell adhesion associated, oncogene regulated	752	0.71
chr3_159570434_159570853	0.28	SCHIP1	schwannomin interacting protein 1	85	0.97
chr9_6938306_6938487	0.28	KDM4C	lysine (K)-specific demethylase 4C	12895	0.26
chr20_9239531_9239912	0.28	PLCB4	phospholipase C, beta 4	41684	0.21
chr3_101654515_101655252	0.28	ENSG00000202177	.	19038	0.23
chr11_9389109_9389260	0.28	IPO7	importin 7	16985	0.17
chr4_22515546_22516022	0.28	GPR125	G protein-coupled receptor 125	1836	0.52
chr1_93273912_93274063	0.28	EVI5	ecotropic viral integration site 5	16026	0.12
chr19_19597935_19598086	0.28	GATAD2A	GATA zinc finger domain containing 2A	21720	0.1
chr3_4382544_4382940	0.28	SETMAR	SET domain and mariner transposase fusion gene	37450	0.21
chr13_97925456_97925607	0.28	MBNL2	muscleblind-like splicing regulator 2	2927	0.38
chr18_72175507_72175658	0.28	CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)	2529	0.29
chr20_48293517_48294318	0.28	B4GALT5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	36498	0.15
chr6_111911908_111912172	0.28	C6orf3		9038	0.17
chr17_14584817_14584968	0.28	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	380492	0.01
chr7_81516797_81516948	0.28	ENSG00000263416	.	32714	0.21
chr4_74698717_74699078	0.28	CXCL6	chemokine (C-X-C motif) ligand 6	3317	0.2
chr22_29292818_29292969	0.28	ZNRF3	zinc and ring finger 3	13003	0.19
chr1_109372448_109372599	0.28	AKNAD1	AKNA domain containing 1	22816	0.15
chr4_103584019_103584226	0.28	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	85101	0.08
chr18_74188097_74188669	0.27	ZNF516	zinc finger protein 516	14352	0.17
chr1_164653921_164654072	0.27	RP11-477H21.2		4674	0.25
chr18_36945725_36946013	0.27	ENSG00000266148	.	310816	0.01
chr6_88616832_88617219	0.27	ENSG00000211983	.	59675	0.12
chr10_7198763_7198958	0.27	SFMBT2	Scm-like with four mbt domains 2	251847	0.02
chr11_77181730_77181925	0.27	DKFZP434E1119		2589	0.26
chr6_42082304_42082455	0.27	C6orf132	chromosome 6 open reading frame 132	27803	0.13
chr1_192491092_192491243	0.27	ENSG00000221145	.	30817	0.18
chr6_140806942_140807093	0.27	ENSG00000221336	.	174833	0.03
chr10_102761652_102761861	0.27	LZTS2	leucine zipper, putative tumor suppressor 2	2146	0.16
chr1_203371608_203371759	0.27	FMOD	fibromodulin	51066	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.1	0.4	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.3	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.3	GO:0070141	response to UV-A(GO:0070141)
0.1	0.2	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.4	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:0061072	iris morphogenesis(GO:0061072)
0.1	0.1	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.0	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.3	GO:0046040	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.1	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.2	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.2	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.2	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.2	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.2	GO:0045628	regulation of T-helper 2 cell differentiation(GO:0045628)
0.0	0.2	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.2	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.1	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.5	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.3	GO:0060438	trachea development(GO:0060438)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.0	0.1	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.0	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.2	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.1	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347) regulation of steroid hormone biosynthetic process(GO:0090030)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.1	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.2	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0060294	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0060737	prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0021799	cerebral cortex radially oriented cell migration(GO:0021799)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.0	0.0	GO:0051284	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0	0.1	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:0035067	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.1	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0006547	histidine metabolic process(GO:0006547)
0.0	0.0	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.0	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.0	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.0	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.0	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0045605	negative regulation of epidermal cell differentiation(GO:0045605)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.0	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0	0.1	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.0	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.0	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.1	GO:0046037	GMP metabolic process(GO:0046037)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.0	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0016265	obsolete death(GO:0016265)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.0	GO:0060602	branch elongation of an epithelium(GO:0060602)
0.0	0.1	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.2	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0033189	response to vitamin A(GO:0033189)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.0	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.1	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0006896	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.0	GO:0021681	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.0	GO:0046884	regulation of follicle-stimulating hormone secretion(GO:0046880) negative regulation of follicle-stimulating hormone secretion(GO:0046882) follicle-stimulating hormone secretion(GO:0046884)
0.0	0.0	GO:0048539	bone marrow development(GO:0048539)
0.0	0.2	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989) low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.0	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.0	GO:0060996	dendritic spine development(GO:0060996)
0.0	0.0	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.0	GO:0035929	steroid hormone secretion(GO:0035929)
0.0	0.1	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.0	GO:0071503	response to heparin(GO:0071503)
0.0	0.0	GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0	0.1	GO:0003407	neural retina development(GO:0003407)
0.0	0.0	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.0	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.0	GO:0097035	regulation of membrane lipid distribution(GO:0097035)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.2	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.3	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0043656	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.3	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.3	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.3	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.0	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.0	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.0	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.7	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.6	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.5	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.8	GO:0001726	ruffle(GO:0001726)
0.0	0.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.2	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.3	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.4	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.2	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.3	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	0.2	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1	0.3	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.3	GO:0045502	dynein binding(GO:0045502)
0.0	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.0	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.3	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.4	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.0	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.0	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.0	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.0	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.2	GO:0008200	ion channel inhibitor activity(GO:0008200)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.0	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.0	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.0	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.4	GO:0004180	carboxypeptidase activity(GO:0004180)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.0	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.0	GO:0050815	phosphoserine binding(GO:0050815)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.2	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.2	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.0	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.4	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.0	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.0	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	0.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.4	REACTOME SIGNAL AMPLIFICATION	Genes involved in Signal amplification
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.0	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis