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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SOX5

Z-value: 1.68

Motif logo

Transcription factors associated with SOX5

Gene Symbol	Gene ID	Gene Info
SOX5 Ensembl NCBI GeneCards UniProt	ENSG00000134532.11	SOX5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
SOX5	chr12_24191758_24191909	87867	0.103921	0.91	7.7e-04	Click!
SOX5	chr12_24198817_24198968	94926	0.093114	0.80	9.8e-03	Click!
SOX5	chr12_24191443_24191594	87552	0.104438	0.77	1.5e-02	Click!
SOX5	chr12_24220325_24220476	116434	0.067774	0.71	3.2e-02	Click!
SOX5	chr12_24198591_24198759	94709	0.093424	0.69	3.8e-02	Click!

Activity of the SOX5 motif across conditions

Conditions sorted by the z-value of the SOX5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_108766828_108767454	0.64	ENSG00000201243	.	109103	0.07
chr3_89006487_89006638	0.52	EPHA3	EPH receptor A3	150112	0.05
chr7_127307740_127308015	0.51	SND1	staphylococcal nuclease and tudor domain containing 1	15643	0.17
chr3_150090237_150090388	0.47	TSC22D2	TSC22 domain family, member 2	35810	0.21
chr3_98498207_98498752	0.46	ST3GAL6	ST3 beta-galactoside alpha-2,3-sialyltransferase 6	8580	0.2
chr6_80714655_80715350	0.40	TTK	TTK protein kinase	451	0.88
chr13_75018762_75018913	0.40	LINC00381	long intergenic non-protein coding RNA 381	25527	0.21
chr4_125861985_125862136	0.40	ANKRD50	ankyrin repeat domain 50	228173	0.02
chr12_25920871_25921133	0.39	ENSG00000222950	.	11501	0.28
chr6_86114884_86115176	0.39	NT5E	5'-nucleotidase, ecto (CD73)	44779	0.19
chr8_49784326_49784477	0.38	SNAI2	snail family zinc finger 2	49587	0.18
chr8_93020286_93020784	0.38	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	9056	0.27
chr3_106946226_106946377	0.38	ENSG00000220989	.	137728	0.05
chr2_202270772_202271289	0.37	ENSG00000202008	.	17206	0.15
chr4_111013040_111013191	0.37	ENSG00000263940	.	25777	0.22
chr10_105814583_105814734	0.37	ENSG00000216083	.	6714	0.19
chr15_45881879_45882313	0.36	BLOC1S6	biogenesis of lysosomal organelles complex-1, subunit 6, pallidin	2073	0.2
chr5_121305331_121305762	0.36	SRFBP1	serum response factor binding protein 1	7890	0.28
chr17_27771115_27771613	0.35	ENSG00000202205	.	1054	0.42
chr1_86020329_86020665	0.35	DDAH1	dimethylarginine dimethylaminohydrolase 1	23436	0.17
chr2_173861229_173861380	0.35	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4	30050	0.2
chr1_78005323_78005533	0.35	AK5	adenylate kinase 5	7636	0.25
chr10_33403329_33403717	0.34	ENSG00000263576	.	15959	0.23
chr2_196440572_196441282	0.34	SLC39A10	solute carrier family 39 (zinc transporter), member 10	226	0.96
chr12_26428456_26429005	0.34	RP11-283G6.5		3877	0.25
chr12_58923583_58923734	0.34	RP11-362K2.2	Protein LOC100506869	14249	0.3
chr6_129988972_129989261	0.34	ARHGAP18	Rho GTPase activating protein 18	42254	0.19
chr8_97117053_97117204	0.34	GDF6	growth differentiation factor 6	55892	0.15
chr18_10169648_10169799	0.34	ENSG00000263630	.	164529	0.03
chr4_169525579_169525730	0.34	PALLD	palladin, cytoskeletal associated protein	27112	0.19
chr9_117881666_117881817	0.34	TNC	tenascin C	1205	0.57
chr1_67397953_67399117	0.34	MIER1	mesoderm induction early response 1, transcriptional regulator	2609	0.29
chr17_67172212_67172518	0.34	ABCA10	ATP-binding cassette, sub-family A (ABC1), member 10	26161	0.18
chr2_158604928_158605079	0.34	ACVR1	activin A receptor, type I	58505	0.13
chr12_109086966_109087316	0.34	CORO1C	coronin, actin binding protein, 1C	3037	0.21
chr10_54078584_54078735	0.33	DKK1	dickkopf WNT signaling pathway inhibitor 1	4603	0.27
chr15_90950843_90951750	0.33	RP11-154B12.3		10183	0.16
chr8_30656566_30656717	0.33	PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	4844	0.26
chr4_74574271_74574566	0.33	IL8	interleukin 8	31805	0.19
chr9_33126556_33126826	0.33	B4GALT1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	1506	0.36
chr4_102277886_102278037	0.33	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme	8526	0.2
chr13_97927391_97927630	0.33	MBNL2	muscleblind-like splicing regulator 2	948	0.7
chr4_40623166_40623743	0.32	RBM47	RNA binding motif protein 47	8427	0.27
chr3_99378263_99378414	0.32	COL8A1	collagen, type VIII, alpha 1	20884	0.22
chr15_64813692_64814396	0.32	ZNF609	zinc finger protein 609	22553	0.15
chr3_47203435_47204414	0.32	SETD2	SET domain containing 2	1142	0.44
chr1_149958228_149958379	0.32	OTUD7B	OTU domain containing 7B	24321	0.11
chr9_18543340_18543491	0.31	ENSG00000264638	.	29889	0.22
chr11_95995991_95996601	0.31	ENSG00000266192	.	78306	0.1
chr1_183048707_183048858	0.31	LAMC1	laminin, gamma 1 (formerly LAMB2)	16897	0.21
chr3_123554337_123554488	0.31	ENSG00000207002	.	21488	0.2
chr6_122116137_122116288	0.31	ENSG00000222659	.	214545	0.02
chr7_134378534_134378685	0.31	BPGM	2,3-bisphosphoglycerate mutase	33436	0.19
chr4_41148645_41148796	0.31	ENSG00000207198	.	32761	0.17
chr2_238131211_238131483	0.31	AC112715.2	Uncharacterized protein	34387	0.2
chr3_58369457_58369608	0.31	PXK	PX domain containing serine/threonine kinase	11869	0.19
chr8_29420742_29420893	0.31	RP4-676L2.1		210130	0.02
chr6_137582633_137582962	0.31	IFNGR1	interferon gamma receptor 1	42211	0.19
chr4_170039270_170039570	0.31	RP11-327O17.2		83525	0.09
chr1_155616109_155616556	0.31	YY1AP1	YY1 associated protein 1	30130	0.11
chr12_122804044_122804253	0.30	CLIP1	CAP-GLY domain containing linker protein 1	41129	0.14
chr6_145276841_145276992	0.30	UTRN	utrophin	156399	0.04
chr15_36663589_36663740	0.30	C15orf41	chromosome 15 open reading frame 41	208148	0.03
chr4_187803291_187803442	0.30	ENSG00000252382	.	24756	0.27
chr9_72730796_72730947	0.30	MAMDC2-AS1	MAMDC2 antisense RNA 1	2095	0.39
chr3_156408207_156408568	0.30	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase	9432	0.23
chr9_3746819_3746970	0.30	RP11-252M18.3		128690	0.05
chr15_89648985_89649136	0.30	ABHD2	abhydrolase domain containing 2	3388	0.22
chr1_16007587_16007940	0.30	PLEKHM2	pleckstrin homology domain containing, family M (with RUN domain) member 2	3064	0.14
chr3_45224538_45224928	0.30	CDCP1	CUB domain containing protein 1	36819	0.15
chr20_43202418_43202569	0.30	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	8697	0.16
chr2_150998613_150998764	0.30	RND3	Rho family GTPase 3	343208	0.01
chr8_123200634_123200785	0.29	ENSG00000238901	.	482821	0.01
chr2_54107765_54107916	0.29	ASB3	Ankyrin repeat and SOCS box protein 3	20543	0.12
chr1_245249651_245249802	0.29	EFCAB2	EF-hand calcium binding domain 2	2968	0.25
chr5_40552129_40552280	0.29	ENSG00000199552	.	102861	0.07
chr1_209549013_209549164	0.29	ENSG00000230937	.	56390	0.16
chr2_102012693_102012844	0.29	CREG2	cellular repressor of E1A-stimulated genes 2	8711	0.24
chr18_42234960_42235111	0.29	SETBP1	SET binding protein 1	25103	0.28
chr14_69560500_69560879	0.29	ENSG00000206768	.	49981	0.13
chr4_177674279_177674430	0.28	VEGFC	vascular endothelial growth factor C	39527	0.21
chr14_61725901_61726197	0.28	ENSG00000252380	.	3701	0.23
chr6_161394793_161394944	0.28	MAP3K4	mitogen-activated protein kinase kinase kinase 4	17891	0.2
chr7_90013531_90013682	0.28	CLDN12	claudin 12	571	0.78
chr5_111071046_111071197	0.28	STARD4-AS1	STARD4 antisense RNA 1	5035	0.22
chr3_187627904_187628178	0.28	BCL6	B-cell CLL/lymphoma 6	164526	0.04
chr13_80510337_80510488	0.28	SPRY2	sprouty homolog 2 (Drosophila)	403382	0.01
chr13_97769047_97769198	0.28	ENSG00000238522	.	59489	0.14
chr2_173148013_173148274	0.28	ENSG00000238572	.	127295	0.05
chr7_16697056_16697503	0.28	BZW2	basic leucine zipper and W2 domains 2	3569	0.24
chr9_14081822_14081973	0.28	NFIB	nuclear factor I/B	98894	0.09
chr7_42232764_42233102	0.28	GLI3	GLI family zinc finger 3	34387	0.25
chr8_49322257_49322678	0.28	ENSG00000252710	.	101877	0.08
chr15_77774031_77774182	0.28	HMG20A	high mobility group 20A	3471	0.32
chr13_93495131_93495400	0.28	GPC5-AS1	GPC5 antisense RNA 1	121398	0.07
chr7_77079843_77080131	0.28	ENSG00000238453	.	26882	0.19
chr6_121836437_121836588	0.28	ENSG00000201379	.	27260	0.18
chr2_177448466_177448617	0.28	ENSG00000252027	.	80863	0.1
chr8_41906632_41907752	0.28	KAT6A	K(lysine) acetyltransferase 6A	2313	0.3
chr1_59231029_59231230	0.28	ENSG00000264081	.	522	0.8
chr10_60462562_60462713	0.27	BICC1	bicaudal C homolog 1 (Drosophila)	90658	0.1
chr4_81158071_81158222	0.27	FGF5	fibroblast growth factor 5	29607	0.18
chr11_95835800_95835951	0.27	MTMR2	myotubularin related protein 2	178416	0.03
chrX_133686261_133686412	0.27	ENSG00000223749	.	5595	0.12
chr9_34455229_34455380	0.27	FAM219A	family with sequence similarity 219, member A	3246	0.15
chr3_141248480_141249204	0.27	RASA2-IT1	RASA2 intronic transcript 1 (non-protein coding)	4867	0.27
chr3_171524560_171524853	0.27	PP13439		3008	0.24
chr14_90388171_90388322	0.27	EFCAB11	EF-hand calcium binding domain 11	32621	0.18
chr9_16416755_16416906	0.27	BNC2	basonuclin 2	19540	0.25
chr1_214691439_214691590	0.27	PTPN14	protein tyrosine phosphatase, non-receptor type 14	33052	0.22
chr1_109373744_109373956	0.27	AKNAD1	AKNA domain containing 1	21489	0.15
chr9_113682774_113682925	0.27	ENSG00000207401	.	13837	0.21
chr10_25162013_25162399	0.27	ENSG00000240294	.	35535	0.19
chr6_75640816_75640967	0.27	COL12A1	collagen, type XII, alpha 1	187883	0.03
chr6_85787494_85787645	0.27	TBX18	T-box 18	313332	0.01
chr2_100630949_100631235	0.27	AFF3	AF4/FMR2 family, member 3	89900	0.09
chr14_101525375_101525526	0.27	ENSG00000207978	.	642	0.17
chr7_116804373_116804524	0.26	ST7-AS2	ST7 antisense RNA 2	17914	0.23
chr2_55329755_55330003	0.26	ENSG00000266376	.	5967	0.21
chr8_32201255_32201406	0.26	ENSG00000200246	.	87318	0.09
chr13_100887218_100887688	0.26	PCCA	propionyl CoA carboxylase, alpha polypeptide	58025	0.16
chr14_76287931_76288578	0.26	RP11-270M14.4		15300	0.24
chr14_72125639_72125790	0.26	SIPA1L1	signal-induced proliferation-associated 1 like 1	40241	0.22
chr12_7186892_7187043	0.26	C1R	complement component 1, r subcomponent	2443	0.18
chr2_13056085_13056236	0.26	ENSG00000264370	.	178667	0.03
chr1_23668057_23668694	0.26	HNRNPR	heterogeneous nuclear ribonucleoprotein R	2380	0.23
chr18_21207209_21207360	0.26	ANKRD29	ankyrin repeat domain 29	22202	0.17
chr1_205513262_205513549	0.26	ENSG00000253097	.	22439	0.13
chr1_222217681_222217979	0.26	ENSG00000212094	.	31398	0.25
chr12_64497608_64497759	0.26	RP11-196H14.2		6285	0.2
chr10_70999026_70999544	0.26	RP11-227H15.4		7039	0.16
chr9_33819892_33820555	0.26	RP11-133O22.6		1430	0.28
chr13_93962486_93962637	0.26	ENSG00000252365	.	58652	0.16
chr2_54436597_54436748	0.26	ENSG00000252934	.	42528	0.15
chr5_39072103_39073220	0.26	RICTOR	RPTOR independent companion of MTOR, complex 2	1830	0.43
chr5_131750080_131750814	0.26	C5orf56	chromosome 5 open reading frame 56	3766	0.16
chr22_36759297_36760367	0.26	MYH9	myosin, heavy chain 9, non-muscle	1324	0.45
chr12_68221054_68221205	0.26	RP11-335O4.3		156430	0.04
chr2_56115274_56115425	0.26	EFEMP1	EGF containing fibulin-like extracellular matrix protein 1	35007	0.17
chr3_42202561_42202898	0.26	TRAK1	trafficking protein, kinesin binding 1	1068	0.61
chr5_167532630_167532980	0.26	ENSG00000253065	.	72595	0.1
chr12_69418582_69418733	0.26	CPM	carboxypeptidase M	61608	0.11
chr6_43046180_43046331	0.26	PTK7	protein tyrosine kinase 7	1703	0.19
chr15_101540006_101540157	0.25	RP11-505E24.3		49580	0.13
chr6_143731949_143732100	0.25	AL031320.1		27551	0.14
chr4_138229530_138229827	0.25	ENSG00000222526	.	80396	0.12
chr2_159353755_159354022	0.25	ENSG00000251721	.	36824	0.14
chr6_38372817_38372968	0.25	ENSG00000238716	.	45887	0.17
chr10_14447511_14447662	0.25	ENSG00000266321	.	22310	0.19
chr6_56732953_56733104	0.25	DST	dystonin	16279	0.2
chr12_47491690_47491841	0.25	AMIGO2	adhesion molecule with Ig-like domain 2	18031	0.21
chr8_102172054_102172205	0.25	ENSG00000202360	.	21942	0.21
chr9_22158686_22158976	0.25	CDKN2B-AS1	CDKN2B antisense RNA 1	45154	0.18
chr4_124339789_124340334	0.25	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	18938	0.3
chr4_57887397_57887548	0.25	ENSG00000251703	.	18614	0.15
chr14_69161214_69161620	0.25	CTD-2325P2.3		9135	0.23
chr7_115872460_115873536	0.25	AC073130.3		6307	0.23
chr3_12689321_12689897	0.25	ENSG00000239140	.	15376	0.17
chr1_215030484_215030635	0.25	KCNK2	potassium channel, subfamily K, member 2	148639	0.05
chr4_170926232_170926383	0.25	MFAP3L	microfibrillar-associated protein 3-like	1372	0.48
chr4_81160064_81160215	0.24	FGF5	fibroblast growth factor 5	27614	0.18
chr9_16180093_16180244	0.24	C9orf92	chromosome 9 open reading frame 92	35729	0.24
chr9_82299998_82300149	0.24	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	19625	0.31
chr1_170506867_170507018	0.24	RP11-576I22.2		5154	0.25
chr13_30700064_30700215	0.24	ENSG00000266816	.	80697	0.11
chr11_68856589_68856851	0.24	ENSG00000265539	.	6076	0.19
chr9_14279801_14279952	0.24	NFIB	nuclear factor I/B	28136	0.22
chr3_151121717_151121896	0.24	P2RY12	purinergic receptor P2Y, G-protein coupled, 12	19206	0.19
chr8_131138127_131138464	0.24	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	7527	0.22
chr7_22617380_22617898	0.24	AC002480.4		11685	0.19
chr4_123820378_123820529	0.24	NUDT6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	13990	0.17
chr4_47855204_47855355	0.24	CORIN	corin, serine peptidase	15156	0.2
chr1_51731801_51732159	0.24	RP11-296A18.6		234	0.91
chr7_17282085_17282236	0.24	AC003075.4		38767	0.19
chr6_130747945_130748096	0.24	TMEM200A	transmembrane protein 200A	5773	0.23
chr14_96723235_96723386	0.24	BDKRB1	bradykinin receptor B1	763	0.53
chr13_46408009_46408289	0.24	SIAH3	siah E3 ubiquitin protein ligase family member 3	17722	0.25
chr7_138619875_138620026	0.24	KIAA1549	KIAA1549	15729	0.22
chr12_94196696_94196920	0.24	ENSG00000264978	.	28044	0.17
chr10_79283821_79283972	0.24	ENSG00000199592	.	62911	0.13
chr1_108558554_108558705	0.24	ENSG00000264753	.	2764	0.32
chr16_8818593_8818759	0.24	ABAT	4-aminobutyrate aminotransferase	4100	0.19
chr10_114423600_114423751	0.24	RP11-25C19.3		13903	0.23
chr2_159975618_159975919	0.24	ENSG00000202029	.	92114	0.08
chr13_40059894_40060045	0.24	ENSG00000238408	.	38616	0.2
chrX_109627247_109627398	0.24	RGAG1	retrotransposon gag domain containing 1	25278	0.18
chr8_96821190_96821341	0.23	ENSG00000223297	.	130122	0.06
chr21_17905685_17905836	0.23	ENSG00000207638	.	5649	0.23
chr3_70905617_70905768	0.23	ENSG00000221382	.	22251	0.24
chr14_53301825_53302222	0.23	FERMT2	fermitin family member 2	29216	0.15
chr6_83778019_83778858	0.23	DOPEY1	dopey family member 1	1048	0.49
chr17_79378177_79378500	0.23	ENSG00000266392	.	3760	0.14
chr3_171542852_171543133	0.23	PLD1	phospholipase D1, phosphatidylcholine-specific	14708	0.17
chr5_102768729_102769023	0.23	NUDT12	nudix (nucleoside diphosphate linked moiety X)-type motif 12	129614	0.05
chr7_80096179_80096330	0.23	GNAT3	guanine nucleotide binding protein, alpha transducing 3	45082	0.17
chr6_113706747_113706898	0.23	ENSG00000222677	.	129367	0.06
chr4_157242892_157243172	0.23	ENSG00000221189	.	25234	0.27
chr6_143165699_143166384	0.23	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	7857	0.29
chr5_87437759_87438959	0.23	TMEM161B	transmembrane protein 161B	78089	0.11
chrX_2729343_2729494	0.23	ENSG00000251848	.	523	0.77

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0051834	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.4	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.3	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.4	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.5	GO:0016199	axon midline choice point recognition(GO:0016199)
0.1	0.5	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.3	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.3	GO:0070141	response to UV-A(GO:0070141)
0.1	0.2	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.1	GO:0042481	regulation of odontogenesis(GO:0042481) regulation of tooth mineralization(GO:0070170)
0.1	0.5	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.2	GO:1902339	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1	0.2	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.3	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.5	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.3	GO:0033197	response to vitamin E(GO:0033197)
0.1	0.2	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.3	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.2	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.2	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.6	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.5	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.3	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.3	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.2	GO:0010662	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.3	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.1	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.1	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	0.1	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.1	0.1	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.2	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.7	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.2	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.2	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.0	GO:0034113	heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.2	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.0	GO:0090190	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.2	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.2	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.5	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.1	GO:0030859	polarized epithelial cell differentiation(GO:0030859) establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.0	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.1	GO:0060242	contact inhibition(GO:0060242)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.5	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.0	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178) negative regulation of stem cell proliferation(GO:2000647)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.4	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.1	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.5	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.2	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.3	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.1	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.3	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.7	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0060998	regulation of dendritic spine development(GO:0060998)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.2	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.1	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.1	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.4	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.0	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.2	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.5	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0031114	regulation of microtubule depolymerization(GO:0031114)
0.0	0.3	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.2	GO:0060840	artery development(GO:0060840)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.0	GO:0010829	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.2	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.2	GO:0019433	triglyceride catabolic process(GO:0019433)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.2	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0071320	cellular response to cAMP(GO:0071320)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.0	GO:0009996	negative regulation of cell fate specification(GO:0009996)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.2	GO:0006693	prostaglandin metabolic process(GO:0006693)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.2	GO:0006972	hyperosmotic response(GO:0006972)
0.0	0.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.3	GO:0006825	copper ion transport(GO:0006825)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.2	GO:0010510	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.0	GO:0009648	photoperiodism(GO:0009648)
0.0	0.1	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0060592	mammary gland formation(GO:0060592)
0.0	0.0	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0060872	semicircular canal development(GO:0060872)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0003407	neural retina development(GO:0003407)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0055026	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.1	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.0	GO:0072205	metanephric collecting duct development(GO:0072205)
0.0	0.0	GO:0048799	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0	0.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.0	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.3	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.0	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.2	GO:1900076	regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.0	GO:0060179	male courtship behavior(GO:0008049) male mating behavior(GO:0060179)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.0	GO:0045683	negative regulation of epidermis development(GO:0045683)
0.0	0.0	GO:0042482	positive regulation of odontogenesis(GO:0042482) positive regulation of tooth mineralization(GO:0070172)
0.0	0.0	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.2	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.0	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.2	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.0	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.0	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.0	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.0	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.0	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.0	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.0	GO:0036445	neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0	0.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0006547	histidine metabolic process(GO:0006547)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0003207	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211) cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.1	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.1	GO:0060395	SMAD protein signal transduction(GO:0060395)
0.0	0.0	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.0	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.0	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0001759	organ induction(GO:0001759)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.0	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0019098	reproductive behavior(GO:0019098)
0.0	0.1	GO:0090280	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0	0.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.0	0.0	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.0	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0033363	secretory granule organization(GO:0033363)
0.0	0.0	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.0	GO:0006244	pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0010171	body morphogenesis(GO:0010171)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.0	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.1	GO:0009219	pyrimidine deoxyribonucleotide metabolic process(GO:0009219)
0.0	0.0	GO:1902224	acetoacetic acid metabolic process(GO:0043438) ketone body metabolic process(GO:1902224)
0.0	0.0	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.4	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.5	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.3	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.3	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.3	GO:0032059	bleb(GO:0032059)
0.1	0.5	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.3	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.3	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.7	GO:0005811	lipid particle(GO:0005811)
0.0	1.0	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.4	GO:0098644	complex of collagen trimers(GO:0098644)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.5	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.2	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.0	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	1.8	GO:0030016	myofibril(GO:0030016)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.8	GO:0016459	myosin complex(GO:0016459)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	1.2	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.7	GO:0005604	basement membrane(GO:0005604)
0.0	0.4	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.0	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.0	GO:0030990	intraciliary transport particle(GO:0030990)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.7	GO:0030027	lamellipodium(GO:0030027)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0009925	basal plasma membrane(GO:0009925)
0.0	2.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.2	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	0.5	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2	0.6	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.4	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.4	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.3	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.4	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0045545	syndecan binding(GO:0045545)
0.1	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.2	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.3	GO:0042805	actinin binding(GO:0042805)
0.1	0.2	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.1	0.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.1	0.3	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.2	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.3	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.5	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.6	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.2	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.6	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	1.1	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0051378	serotonin binding(GO:0051378)
0.0	0.3	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432) calcium:cation antiporter activity(GO:0015368)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.2	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.3	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.0	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.2	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.2	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.0	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.0	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.0	GO:0034618	arginine binding(GO:0034618)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.0	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.0	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.0	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.2	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.1	0.6	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.4	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.8	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	1.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.7	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.3	PID BMP PATHWAY	BMP receptor signaling
0.0	0.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	1.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.3	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.6	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.0	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.3	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.1	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.1	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions