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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for SOX6

Z-value: 0.79

Motif logo

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Transcription factors associated with SOX6

Gene Symbol Gene ID Gene Info
SOX6
ENSG00000110693.11 SRY-box transcription factor 6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_16359378_16359529SOX633620.386357-0.393.0e-01Click!
chr11_16532906_16533057SOX6350460.2063600.333.9e-01Click!
chr11_16360095_16360246SOX626450.425356-0.324.0e-01Click!
chr11_16371663_16371814SOX689230.316904-0.304.3e-01Click!
chr11_16378441_16378592SOX6157010.2954280.304.3e-01Click!

Activity of the SOX6 motif across conditions

Conditions sorted by the z-value of the SOX6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_77229212_77229699 0.24 RP11-399K21.10
38109
 0.16
chr9_695641_695792 0.24 RP11-130C19.3
10161
 0.22
chr8_49533767_49533918 0.23 RP11-770E5.1
69715
 0.13
chr8_8458649_8458942 0.23 ENSG00000263616
 .
 18630
 0.21
chr16_8818593_8818759 0.22 ABAT
 4-aminobutyrate aminotransferase
 4100
 0.19
chr10_4813889_4814086 0.21 AKR1E2
 aldo-keto reductase family 1, member E2
 14834
 0.27
chr5_114919475_114919626 0.21 AC010226.4
18204
 0.15
chr9_79316323_79316721 0.20 PRUNE2
 prune homolog 2 (Drosophila)
 8631
 0.24
chr4_14171315_14171588 0.19 ENSG00000252092
 .
 511200
 0.0
chr6_3842256_3842407 0.19 FAM50B
 family with sequence similarity 50, member B
 7289
 0.21
chr5_9623691_9623842 0.19 TAS2R1
 taste receptor, type 2, member 1
 6697
 0.23
chr3_138581340_138581807 0.19 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 27793
 0.2
chr13_97769047_97769198 0.19 ENSG00000238522
 .
 59489
 0.14
chr11_124768633_124768970 0.18 ROBO4
 roundabout, axon guidance receptor, homolog 4 (Drosophila)
 624
 0.57
chr3_171922499_171922892 0.18 ENSG00000243398
 .
 32421
 0.2
chr17_76370784_76371498 0.18 PGS1
 phosphatidylglycerophosphate synthase 1
 3580
 0.16
chr17_39216444_39216595 0.18 KRTAP2-3
 keratin associated protein 2-3
 175
 0.84
chr1_52024489_52024927 0.17 OSBPL9
 oxysterol binding protein-like 9
 18143
 0.15
chr6_111738388_111738782 0.17 REV3L-IT1
 REV3L intronic transcript 1 (non-protein coding)
 55775
 0.11
chr1_185369945_185370096 0.17 ENSG00000252407
 .
 33356
 0.19
chr6_158595918_158596069 0.17 ENSG00000265803
 .
 23
 0.98
chr12_1459164_1459315 0.17 RP5-951N9.2
35760
 0.17
chr3_65980527_65980678 0.17 ENSG00000202071
 .
 9013
 0.2
chr9_118705597_118705748 0.17 PAPPA
 pregnancy-associated plasma protein A, pappalysin 1
 210411
 0.02
chr3_89006487_89006638 0.17 EPHA3
 EPH receptor A3
 150112
 0.05
chr2_192135580_192135731 0.16 MYO1B
 myosin IB
 5956
 0.29
chr2_121044269_121044420 0.16 RALB
 v-ral simian leukemia viral oncogene homolog B
 33317
 0.16
chr2_28019558_28020090 0.16 AC110084.1
10638
 0.17
chr16_86618940_86619091 0.16 FOXL1
 forkhead box L1
 6900
 0.18
chr7_129515845_129516123 0.16 UBE2H
 ubiquitin-conjugating enzyme E2H
 75183
 0.07
chr1_162726043_162726194 0.16 DDR2
 discoidin domain receptor tyrosine kinase 2
 10909
 0.19
chr1_98552609_98552760 0.16 ENSG00000225206
 .
 40957
 0.22
chr9_74656389_74656748 0.16 C9orf57
 chromosome 9 open reading frame 57
 18953
 0.24
chr10_113962717_113962868 0.16 GPAM
 glycerol-3-phosphate acyltransferase, mitochondrial
 19267
 0.25
chr5_111341016_111341167 0.16 NREP
 neuronal regeneration related protein
 7930
 0.25
chr6_7692718_7692971 0.16 BMP6
 bone morphogenetic protein 6
 34186
 0.21
chr4_174241133_174241334 0.16 RP11-798M19.3
9612
 0.14
chr11_113544876_113545027 0.16 TMPRSS5
 transmembrane protease, serine 5
 32073
 0.18
chr8_18707793_18707944 0.16 PSD3
 pleckstrin and Sec7 domain containing 3
 4016
 0.3
chr8_67430180_67430331 0.15 ENSG00000206949
 .
 16709
 0.18
chr5_123932985_123933136 0.15 RP11-436H11.2
131464
 0.05
chr21_30877086_30877237 0.15 BACH1-IT3
 BACH1 intronic transcript 3 (non-protein coding)
 8794
 0.25
chr13_110954877_110955028 0.15 COL4A2
 collagen, type IV, alpha 2
 3207
 0.28
chrX_17482771_17482922 0.15 ENSG00000265465
 .
 38842
 0.17
chr7_41046808_41047238 0.15 AC005160.3
231866
 0.02
chr10_104990883_104991034 0.15 RPEL1
 ribulose-5-phosphate-3-epimerase-like 1
 14686
 0.17
chr4_169769529_169769764 0.15 RP11-635L1.3
15558
 0.19
chr4_55063559_55063710 0.15 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
 31630
 0.19
chr18_57387136_57387287 0.15 CCBE1
 collagen and calcium binding EGF domains 1
 22599
 0.15
chr7_129996471_129996836 0.15 CPA5
 carboxypeptidase A5
 6629
 0.14
chr6_7697424_7697575 0.15 BMP6
 bone morphogenetic protein 6
 29531
 0.22
chr14_59803989_59804140 0.15 ENSG00000252869
 .
 62677
 0.12
chr6_129988972_129989261 0.15 ARHGAP18
 Rho GTPase activating protein 18
 42254
 0.19
chr10_119199218_119199369 0.15 EMX2OS
 EMX2 opposite strand/antisense RNA
 37391
 0.17
chr1_94219801_94219965 0.15 RP11-488P3.1
21117
 0.21
chr14_62083033_62083184 0.15 RP11-47I22.3
 Uncharacterized protein
 31030
 0.19
chr8_25045009_25045650 0.15 DOCK5
 dedicator of cytokinesis 5
 2949
 0.31
chr7_134303351_134303502 0.15 BPGM
 2,3-bisphosphoglycerate mutase
 28134
 0.2
chr5_159509880_159510031 0.15 PWWP2A
 PWWP domain containing 2A
 36474
 0.14
chr2_192251959_192252110 0.15 MYO1B
 myosin IB
 4826
 0.27
chr18_6731603_6731754 0.14 ARHGAP28
 Rho GTPase activating protein 28
 1636
 0.35
chr1_214645068_214645257 0.14 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 7016
 0.3
chr12_66289441_66289878 0.14 RP11-366L20.2
 Uncharacterized protein
 13712
 0.17
chr9_38038631_38039019 0.14 SHB
 Src homology 2 domain containing adaptor protein B
 30383
 0.2
chr2_45465707_45466004 0.14 SIX2
 SIX homeobox 2
 229286
 0.02
chr12_65919247_65919398 0.14 MSRB3
 methionine sulfoxide reductase B3
 198667
 0.03
chr11_108777777_108777928 0.14 ENSG00000201243
 .
 98392
 0.08
chr8_40381376_40381655 0.14 ZMAT4
 zinc finger, matrin-type 4
 364549
 0.01
chr20_33225732_33225883 0.14 PIGU
 phosphatidylinositol glycan anchor biosynthesis, class U
 21910
 0.18
chr12_66006270_66006421 0.14 HMGA2
 high mobility group AT-hook 2
 211566
 0.02
chr2_173148013_173148274 0.14 ENSG00000238572
 .
 127295
 0.05
chr4_110000359_110000510 0.14 COL25A1
 collagen, type XXV, alpha 1
 223089
 0.02
chr2_85381280_85381580 0.14 TCF7L1
 transcription factor 7-like 1 (T-cell specific, HMG-box)
 20897
 0.16
chr8_107058539_107058690 0.14 ENSG00000251003
 .
 14057
 0.29
chr4_157242892_157243172 0.14 ENSG00000221189
 .
 25234
 0.27
chr9_94257425_94257576 0.14 NFIL3
 nuclear factor, interleukin 3 regulated
 71356
 0.13
chrX_19593273_19593424 0.14 MAP3K15
 mitogen-activated protein kinase kinase kinase 15
 59969
 0.14
chr6_148650833_148650984 0.14 SASH1
 SAM and SH3 domain containing 1
 12821
 0.24
chr8_19041447_19041598 0.14 PSD3
 pleckstrin and Sec7 domain containing 3
 99282
 0.08
chr2_152190772_152190995 0.14 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
 23223
 0.15
chr12_49653469_49653759 0.14 RP11-977B10.2
4925
 0.12
chr14_68943525_68944196 0.14 RAD51B
 RAD51 paralog B
 65633
 0.13
chr5_178078966_178079117 0.14 CLK4
 CDC-like kinase 4
 24926
 0.17
chr3_171549465_171549722 0.14 TMEM212
 transmembrane protein 212
 11546
 0.18
chr3_30537171_30537700 0.14 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 110559
 0.07
chr1_101088325_101088476 0.14 GPR88
 G protein-coupled receptor 88
 84707
 0.09
chr3_110529262_110529413 0.14 RP11-553A10.1
 Uncharacterized protein
 82722
 0.1
chr5_54734133_54734284 0.14 SKIV2L2
 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
 22324
 0.2
chr6_14713773_14713924 0.14 ENSG00000206960
 .
 67082
 0.15
chr14_25590830_25590981 0.14 STXBP6
 syntaxin binding protein 6 (amisyn)
 71402
 0.13
chr11_128077954_128078105 0.14 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 297260
 0.01
chr9_124487659_124487810 0.14 DAB2IP
 DAB2 interacting protein
 17330
 0.25
chr18_32353571_32353898 0.14 RP11-138H11.1
6107
 0.24
chr4_48256106_48256549 0.14 TEC
 tec protein tyrosine kinase
 15554
 0.23
chr6_18047583_18047734 0.14 KIF13A
 kinesin family member 13A
 59804
 0.12
chr9_18673255_18673406 0.14 ENSG00000252960
 .
 22185
 0.25
chr16_11443797_11444179 0.14 RP11-485G7.6
810
 0.38
chr14_64887580_64888013 0.14 CTD-2555O16.4
21160
 0.12
chr2_161887841_161887992 0.14 TANK
 TRAF family member-associated NFKB activator
 105503
 0.07
chr1_172888000_172888151 0.14 TNFSF18
 tumor necrosis factor (ligand) superfamily, member 18
 131981
 0.05
chr2_153272362_153272513 0.14 FMNL2
 formin-like 2
 80686
 0.11
chr8_13081961_13082497 0.14 DLC1
 deleted in liver cancer 1
 51826
 0.15
chr4_141865088_141865239 0.14 RNF150
 ring finger protein 150
 53027
 0.16
chr12_64256232_64256383 0.13 RP11-274J7.2
16260
 0.15
chr3_57198236_57199040 0.13 IL17RD
 interleukin 17 receptor D
 765
 0.66
chr15_38170580_38170731 0.13 TMCO5A
 transmembrane and coiled-coil domains 5A
 43485
 0.22
chr9_94579747_94580327 0.13 ROR2
 receptor tyrosine kinase-like orphan receptor 2
 131125
 0.05
chr1_181110732_181111665 0.13 IER5
 immediate early response 5
 53560
 0.15
chr2_119132864_119133015 0.13 INSIG2
 insulin induced gene 2
 286889
 0.01
chr17_67650855_67651006 0.13 MAP2K6
 mitogen-activated protein kinase kinase 6
 152360
 0.04
chr19_41139813_41139964 0.13 LTBP4
 latent transforming growth factor beta binding protein 4
 20066
 0.12
chr8_117243679_117243852 0.13 ENSG00000264815
 .
 55823
 0.16
chr15_35998212_35998363 0.13 DPH6
 diphthamine biosynthesis 6
 159894
 0.04
chr6_113203227_113203573 0.13 ENSG00000201386
 .
 89295
 0.1
chr1_100056261_100056412 0.13 PALMD
 palmdelphin
 55163
 0.15
chr12_69446255_69446406 0.13 ENSG00000252547
 .
 65102
 0.11
chr4_26022444_26022595 0.13 SMIM20
 small integral membrane protein 20
 106588
 0.07
chr1_206507740_206507891 0.13 SRGAP2
 SLIT-ROBO Rho GTPase activating protein 2
 8385
 0.23
chr5_137840619_137840770 0.13 ETF1
 eukaryotic translation termination factor 1
 36706
 0.11
chr9_79282166_79282658 0.13 ENSG00000265488
 .
 1410
 0.48
chr15_38691031_38691182 0.13 FAM98B
 family with sequence similarity 98, member B
 55222
 0.14
chr11_129862720_129862871 0.13 PRDM10
 PR domain containing 10
 9885
 0.24
chr10_127895752_127895903 0.13 ENSG00000222740
 .
 61676
 0.14
chr9_6498816_6498967 0.13 C9orf38
 chromosome 9 open reading frame 38
 28516
 0.15
chr12_81602381_81602532 0.13 ENSG00000265227
 .
 50289
 0.14
chr8_129071417_129071568 0.13 ENSG00000221176
 .
 10094
 0.21
chr1_156280745_156281007 0.13 VHLL
 von Hippel-Lindau tumor suppressor-like
 11448
 0.09
chr17_14821652_14821803 0.13 ENSG00000238806
 .
 319473
 0.01
chr3_181348644_181348795 0.13 SOX2-OT
 SOX2 overlapping transcript (non-protein coding)
 20322
 0.26
chr22_29147024_29147175 0.13 CHEK2
 checkpoint kinase 2
 8689
 0.14
chr11_120269083_120269234 0.13 ARHGEF12
 Rho guanine nucleotide exchange factor (GEF) 12
 13155
 0.21
chr7_77038606_77038979 0.13 GSAP
 gamma-secretase activating protein
 6392
 0.24
chr6_35937826_35937977 0.13 SRPK1
 SRSF protein kinase 1
 48782
 0.12
chr7_116804373_116804524 0.13 ST7-AS2
 ST7 antisense RNA 2
 17914
 0.23
chr1_59348718_59349141 0.13 JUN
 jun proto-oncogene
 99144
 0.08
chr15_101265712_101265890 0.13 ENSG00000212306
 .
 87233
 0.08
chr5_52109798_52109949 0.13 CTD-2288O8.1
26013
 0.17
chr5_82771804_82772197 0.13 VCAN
 versican
 4256
 0.33
chr18_25422906_25423057 0.13 AC015933.2
111502
 0.07
chr18_48380885_48381112 0.13 ME2
 malic enzyme 2, NAD(+)-dependent, mitochondrial
 24421
 0.19
chr11_9173045_9173196 0.13 DENND5A
 DENN/MADD domain containing 5A
 834
 0.63
chr9_95007298_95007449 0.13 IARS
 isoleucyl-tRNA synthetase
 10
 0.98
chr10_53129972_53130123 0.13 RP11-539E19.2
67721
 0.11
chr15_48885053_48885221 0.13 FBN1
 fibrillin 1
 52781
 0.16
chr1_186937122_186937273 0.13 PLA2G4A
 phospholipase A2, group IVA (cytosolic, calcium-dependent)
 139075
 0.05
chr6_8083142_8083550 0.13 EEF1E1
 eukaryotic translation elongation factor 1 epsilon 1
 14198
 0.22
chr2_190140790_190141071 0.13 ENSG00000266817
 .
 35557
 0.2
chr15_75986048_75986554 0.13 AC105020.1
 Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
 15629
 0.09
chr20_4879353_4879628 0.13 SLC23A2
 solute carrier family 23 (ascorbic acid transporter), member 2
 803
 0.62
chr7_94042885_94043036 0.13 COL1A2
 collagen, type I, alpha 2
 19087
 0.24
chr8_102472574_102472725 0.13 GRHL2
 grainyhead-like 2 (Drosophila)
 32011
 0.17
chr1_201435279_201435430 0.13 PHLDA3
 pleckstrin homology-like domain, family A, member 3
 2958
 0.22
chr15_83223579_83223730 0.13 RP11-152F13.10
1028
 0.4
chr4_141158577_141158955 0.13 SCOC
 short coiled-coil protein
 19674
 0.2
chr20_9389511_9389662 0.13 PLCB4
 phospholipase C, beta 4
 101139
 0.07
chr9_117567236_117567387 0.12 TNFSF15
 tumor necrosis factor (ligand) superfamily, member 15
 1095
 0.57
chr17_7649362_7649654 0.12 DNAH2
 dynein, axonemal, heavy chain 2
 26469
 0.09
chr5_156891952_156892205 0.12 CTB-109A12.1
4992
 0.18
chr8_49181983_49182134 0.12 ENSG00000252710
 .
 38532
 0.22
chr1_86020329_86020665 0.12 DDAH1
 dimethylarginine dimethylaminohydrolase 1
 23436
 0.17
chr12_91520735_91520886 0.12 LUM
 lumican
 15202
 0.21
chr14_55118503_55118654 0.12 SAMD4A
 sterile alpha motif domain containing 4A
 83941
 0.09
chr12_122804044_122804253 0.12 CLIP1
 CAP-GLY domain containing linker protein 1
 41129
 0.14
chr9_111506066_111506342 0.12 ACTL7B
 actin-like 7B
 113035
 0.06
chr3_170407906_170408107 0.12 RP11-373E16.3
33655
 0.21
chr2_109860627_109860778 0.12 ENSG00000265965
 .
 69379
 0.12
chr12_50482074_50482225 0.12 SMARCD1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
 131
 0.93
chr6_52377403_52377554 0.12 TRAM2
 translocation associated membrane protein 2
 64235
 0.11
chr13_44954356_44954507 0.12 SERP2
 stress-associated endoplasmic reticulum protein family member 2
 6453
 0.29
chr15_38556668_38556819 0.12 SPRED1
 sprouty-related, EVH1 domain containing 1
 11361
 0.31
chr3_127778796_127778947 0.12 SEC61A1
 Sec61 alpha 1 subunit (S. cerevisiae)
 7269
 0.16
chr7_78066865_78067016 0.12 MAGI2
 membrane associated guanylate kinase, WW and PDZ domain containing 2
 333456
 0.01
chr1_161055056_161055207 0.12 RP11-544M22.8
876
 0.33
chr6_122013544_122013695 0.12 ENSG00000222659
 .
 111952
 0.07
chr20_10286775_10287859 0.12 ENSG00000211588
 .
 55561
 0.13
chr1_185941569_185941720 0.12 HMCN1
 hemicentin 1
 198875
 0.03
chr1_155732961_155733524 0.12 DAP3
 death associated protein 3
 26439
 0.13
chr15_35598915_35599148 0.12 ENSG00000265102
 .
 65534
 0.14
chr6_125424201_125424520 0.12 TPD52L1
 tumor protein D52-like 1
 15835
 0.26
chr11_12708464_12708615 0.12 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
 11489
 0.28
chr19_15359313_15359464 0.12 EPHX3
 epoxide hydrolase 3
 15142
 0.16
chr9_134307769_134307920 0.12 PRRC2B
 proline-rich coiled-coil 2B
 2312
 0.3
chr17_6494691_6494964 0.12 KIAA0753
 KIAA0753
 3492
 0.17
chr6_26525862_26526131 0.12 ENSG00000199289
 .
 6310
 0.15
chr12_92683552_92683850 0.12 ENSG00000199895
 .
 119472
 0.05
chr7_44920062_44920690 0.12 ENSG00000264326
 .
 1023
 0.4
chr21_30166964_30167115 0.12 ENSG00000251894
 .
 51509
 0.16
chr12_2446318_2446693 0.12 CACNA1C-IT3
 CACNA1C intronic transcript 3 (non-protein coding)
 67563
 0.12
chr11_121525626_121526436 0.12 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 64903
 0.15
chr2_226943894_226944045 0.12 ENSG00000263363
 .
 579540
 0.0
chr9_34992193_34992462 0.12 DNAJB5
 DnaJ (Hsp40) homolog, subfamily B, member 5
 542
 0.7
chr1_39619924_39620199 0.12 ENSG00000222378
 .
 93
 0.97
chr14_54575381_54575532 0.12 BMP4
 bone morphogenetic protein 4
 149977
 0.04
chr9_112580010_112580308 0.12 AKAP2
 A kinase (PRKA) anchor protein 2
 37390
 0.14
chr3_17794774_17794953 0.12 TBC1D5
 TBC1 domain family, member 5
 10719
 0.3
chr5_60624415_60624676 0.12 ZSWIM6
 zinc finger, SWIM-type containing 6
 3555
 0.36
chr6_157471173_157471324 0.12 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 1203
 0.58
chr9_118999659_118999922 0.12 ENSG00000221772
 .
 38432
 0.15
chr1_225843948_225844099 0.12 ENAH
 enabled homolog (Drosophila)
 3179
 0.27
chr6_148886468_148886619 0.12 ENSG00000223322
 .
 41167
 0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.2 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.2 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.2 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.2 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.2 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0035929 steroid hormone secretion(GO:0035929)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0010667 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.2 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.0 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.0 0.0 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.0 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.0 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.0 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.0 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.0 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.0 GO:0060013 righting reflex(GO:0060013)
0.0 0.0 GO:0061047 positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.0 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.3 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.0 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.3 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.0 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0015368 calcium:cation antiporter activity(GO:0015368)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.0 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.5 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0016972 thiol oxidase activity(GO:0016972)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.0 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.0 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis