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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for SP1

Z-value: 3.74

Motif logo

Transcription factors associated with SP1

Gene Symbol	Gene ID	Gene Info
SP1 Ensembl NCBI GeneCards UniProt	ENSG00000185591.5	SP1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
SP1	chr12_53772586_53772854	1240	0.344652	-0.86	2.7e-03	Click!
SP1	chr12_53772905_53773101	957	0.439678	-0.82	6.9e-03	Click!
SP1	chr12_53776548_53777523	1949	0.228476	-0.82	6.9e-03	Click!
SP1	chr12_53759898_53760102	13960	0.111090	-0.79	1.1e-02	Click!
SP1	chr12_53765461_53765679	8390	0.121870	-0.76	1.9e-02	Click!

Activity of the SP1 motif across conditions

Conditions sorted by the z-value of the SP1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_7989733_7990535	5.20	CTD-3193O13.8		752	0.29
chr14_103986978_103987655	4.39	CKB	creatine kinase, brain	122	0.92
chr19_3479375_3479999	3.68	C19orf77	chromosome 19 open reading frame 77	601	0.61
chr14_24837858_24838637	3.62	NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	41	0.94
chr11_61062635_61063418	3.42	VWCE	von Willebrand factor C and EGF domains	130	0.94
chr11_70963344_70963766	3.32	SHANK2	SH3 and multiple ankyrin repeat domains 2	68	0.98
chr6_43243469_43244256	3.27	SLC22A7	solute carrier family 22 (organic anion transporter), member 7	21874	0.11
chr7_1704828_1705261	3.11	ELFN1	extracellular leucine-rich repeat and fibronectin type III domain containing 1	22711	0.17
chr10_134755869_134756456	3.08	TTC40	tetratricopeptide repeat domain 40	73	0.98
chr1_220863452_220864325	3.07	C1orf115	chromosome 1 open reading frame 115	701	0.71
chr19_47524229_47524951	3.07	NPAS1	neuronal PAS domain protein 1	447	0.8
chr7_73868587_73869056	3.04	GTF2IRD1	GTF2I repeat domain containing 1	382	0.88
chr6_35457763_35458156	2.93	TEAD3	TEA domain family member 3	6768	0.17
chr19_1513130_1513873	2.89	ADAMTSL5	ADAMTS-like 5	313	0.73
chr5_60921647_60922495	2.84	C5orf64	chromosome 5 open reading frame 64	11565	0.22
chr8_142424232_142425134	2.80	PTP4A3	protein tyrosine phosphatase type IVA, member 3	7324	0.13
chr11_45943688_45944157	2.78	GYLTL1B	glycosyltransferase-like 1B	321	0.82
chr19_17716649_17717262	2.78	CTD-3149D2.3		7576	0.15
chr8_145017107_145017820	2.76	PLEC	plectin	663	0.52
chr1_36173339_36173885	2.69	ENSG00000239859	.	1737	0.31
chr1_154989037_154989850	2.63	ZBTB7B	zinc finger and BTB domain containing 7B	2519	0.11
chr22_46933945_46934657	2.60	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1	1234	0.46
chr17_7746157_7747127	2.56	KDM6B	lysine (K)-specific demethylase 6B	1591	0.22
chr11_118791485_118792723	2.55	BCL9L	B-cell CLL/lymphoma 9-like	2491	0.13
chr1_52456038_52456544	2.53	RAB3B	RAB3B, member RAS oncogene family	145	0.93
chr15_69222625_69222878	2.50	SPESP1	sperm equatorial segment protein 1	88	0.53
chr1_3691739_3692479	2.50	SMIM1	small integral membrane protein 1 (Vel blood group)	2482	0.16
chr14_95785263_95786111	2.48	CLMN	calmin (calponin-like, transmembrane)	556	0.83
chr3_47619822_47620139	2.37	CSPG5	chondroitin sulfate proteoglycan 5 (neuroglycan C)	357	0.84
chr19_36360617_36361346	2.36	APLP1	amyloid beta (A4) precursor-like protein 1	105	0.92
chr2_241391852_241392233	2.35	GPC1	glypican 1	186	0.93
chr16_88518586_88519370	2.35	ZFPM1	zinc finger protein, FOG family member 1	747	0.63
chr17_36575458_36576074	2.33	ARHGAP23	Rho GTPase activating protein 23	8896	0.15
chr11_417004_417487	2.30	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	80	0.94
chr1_41130861_41131209	2.28	RIMS3	regulating synaptic membrane exocytosis 3	82	0.97
chr17_77788487_77789261	2.28	ENSG00000238331	.	4396	0.16
chr15_41786624_41787259	2.24	ITPKA	inositol-trisphosphate 3-kinase A	868	0.5
chr16_89258494_89259013	2.21	SLC22A31	solute carrier family 22, member 31	9319	0.12
chr5_175299080_175299718	2.16	CPLX2	complexin 2	414	0.87
chr19_709223_709862	2.15	PALM	paralemmin	441	0.7
chr13_114898126_114898522	2.12	RASA3	RAS p21 protein activator 3	238	0.94
chr15_74906801_74907591	2.11	CLK3	CDC-like kinase 3	26	0.93
chr17_38227673_38228382	2.09	THRA	thyroid hormone receptor, alpha	317	0.83
chr1_6301763_6302398	2.07	HES3	hes family bHLH transcription factor 3	2172	0.18
chr22_33197200_33197644	2.05	TIMP3	TIMP metallopeptidase inhibitor 3	265	0.94
chr16_49315668_49315968	2.05	CBLN1	cerebellin 1 precursor	76	0.98
chr17_38500621_38501691	2.04	RARA	retinoic acid receptor, alpha	337	0.77
chr19_15559479_15560330	2.03	ENSG00000269782	.	455	0.47
chr16_203573_203998	2.02	HBZ	hemoglobin, zeta	1099	0.28
chr16_214202_214642	1.97	HBM	hemoglobin, mu	1555	0.19
chr5_139283800_139284387	1.94	NRG2	neuregulin 2	111	0.97
chr1_53528255_53528820	1.94	PODN	podocan	652	0.65
chr2_42795325_42795726	1.94	MTA3	metastasis associated 1 family, member 3	132	0.97
chr19_50433408_50433958	1.91	ATF5	activating transcription factor 5	207	0.7
chr19_45995891_45996348	1.89	RTN2	reticulon 2	406	0.74
chr19_19245450_19245992	1.88	TMEM161A	transmembrane protein 161A	2511	0.19
chr11_119019793_119020192	1.86	ABCG4	ATP-binding cassette, sub-family G (WHITE), member 4	29	0.94
chr11_65343918_65345038	1.83	EHBP1L1	EH domain binding protein 1-like 1	961	0.3
chr11_65555313_65555947	1.83	OVOL1	ovo-like zinc finger 1	1137	0.27
chr22_35710419_35710852	1.81	TOM1	target of myb1 (chicken)	3580	0.2
chr14_105993130_105993899	1.81	TMEM121	transmembrane protein 121	574	0.65
chrX_153095505_153095958	1.81	PDZD4	PDZ domain containing 4	82	0.94
chr10_133999367_134000256	1.76	RP11-140A10.3		345	0.67
chr1_1631163_1631760	1.76	SLC35E2B	solute carrier family 35, member E2B	7294	0.11
chr8_127570759_127570910	1.74	FAM84B	family with sequence similarity 84, member B	196	0.83
chrX_13956325_13956738	1.73	GPM6B	glycoprotein M6B	3	0.99
chr6_35181746_35182466	1.73	SCUBE3	signal peptide, CUB domain, EGF-like 3	84	0.97
chr22_47031090_47031241	1.72	GRAMD4	GRAM domain containing 4	8507	0.25
chr19_6373582_6374209	1.72	ALKBH7	alkB, alkylation repair homolog 7 (E. coli)	180	0.87
chr19_33716510_33717125	1.71	SLC7A10	solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10	61	0.96
chr19_41035362_41036035	1.69	SPTBN4	spectrin, beta, non-erythrocytic 4	697	0.62
chr6_21596350_21596989	1.68	SOX4	SRY (sex determining region Y)-box 4	2598	0.45
chr8_140716343_140716851	1.62	KCNK9	potassium channel, subfamily K, member 9	1298	0.63
chr2_218867994_218868369	1.60	TNS1	tensin 1	463	0.82
chr10_72647360_72647920	1.59	PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	901	0.61
chr11_118780857_118781283	1.55	ENSG00000264211	.	347	0.56
chr16_330808_331389	1.55	ARHGDIG	Rho GDP dissociation inhibitor (GDI) gamma	243	0.84
chr11_8102991_8103508	1.54	TUB	tubby bipartite transcription factor	340	0.86
chr19_891680_892010	1.54	MED16	mediator complex subunit 16	697	0.42
chr1_114696395_114696727	1.51	SYT6	synaptotagmin VI	20	0.99
chr8_144678451_144679037	1.50	EEF1D	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	180	0.83
chr11_67573557_67574049	1.50	FAM86C2P	family with sequence similarity 86, member C2, pseudogene	1019	0.55
chr7_75889672_75889823	1.50	SRRM3	serine/arginine repetitive matrix 3	22185	0.15
chr11_118016566_118017132	1.49	SCN4B	sodium channel, voltage-gated, type IV, beta subunit	6686	0.16
chr19_54975261_54975635	1.49	LENG9	leukocyte receptor cluster (LRC) member 9	554	0.57
chr11_107799088_107799595	1.49	RAB39A	RAB39A, member RAS oncogene family	112	0.77
chr11_118789955_118791011	1.48	BCL9L	B-cell CLL/lymphoma 9-like	870	0.37
chr9_127533936_127534490	1.47	NR6A1	nuclear receptor subfamily 6, group A, member 1	624	0.61
chr9_124976369_124976520	1.46	LHX6	LIM homeobox 6	243	0.9
chr12_6809250_6809799	1.45	PIANP	PILR alpha associated neural protein	72	0.93
chr14_105330710_105331361	1.44	CEP170B	centrosomal protein 170B	582	0.74
chr3_47844781_47845806	1.43	DHX30	DEAH (Asp-Glu-Ala-His) box helicase 30	638	0.69
chr17_40673744_40674238	1.42	ENSG00000265611	.	7785	0.08
chr17_7739988_7740840	1.42	KDM6B	lysine (K)-specific demethylase 6B	2808	0.14
chr1_9352292_9352820	1.41	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	383	0.87
chr12_106533043_106533555	1.40	NUAK1	NUAK family, SNF1-like kinase, 1	512	0.83
chr1_16353119_16353557	1.39	CLCNKA	chloride channel, voltage-sensitive Ka	4791	0.12
chr21_47714776_47715544	1.39	YBEY	ybeY metallopeptidase (putative)	8601	0.11
chr17_74523485_74524063	1.37	CYGB	cytoglobin	4373	0.1
chr9_137037215_137037601	1.37	ENSG00000221676	.	7722	0.2
chr15_83378361_83379204	1.37	AP3B2	adaptor-related protein complex 3, beta 2 subunit	116	0.95
chr17_26698665_26699277	1.36	SARM1	sterile alpha and TIR motif containing 1	288	0.7
chr2_25475353_25475794	1.35	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	393	0.88
chr22_19718359_19718998	1.34	GP1BB	glycoprotein Ib (platelet), beta polypeptide	8210	0.17
chr15_41221926_41222903	1.34	DLL4	delta-like 4 (Drosophila)	823	0.5
chr7_35576796_35577240	1.34	HERPUD2	HERPUD family member 2	157158	0.04
chr12_120426537_120426688	1.34	CCDC64	coiled-coil domain containing 64	1061	0.58
chr9_132020554_132020853	1.34	ENSG00000220992	.	27707	0.15
chr17_80010173_80011309	1.34	GPS1	G protein pathway suppressor 1	632	0.4
chr15_66914780_66915271	1.34	RP11-321F6.1	HCG2003567; Uncharacterized protein	40497	0.12
chr19_18896645_18896796	1.34	COMP	cartilage oligomeric matrix protein	5394	0.17
chr7_128431078_128431544	1.33	CCDC136	coiled-coil domain containing 136	153	0.93
chr19_10870035_10870582	1.33	ENSG00000265879	.	20622	0.11
chr16_89149708_89149925	1.32	ACSF3	acyl-CoA synthetase family member 3	4967	0.19
chr20_34129990_34130743	1.30	ERGIC3	ERGIC and golgi 3	487	0.7
chr13_114428750_114429093	1.30	TMEM255B	transmembrane protein 255B	33295	0.18
chr16_1202380_1202675	1.29	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit	714	0.52
chr19_47163781_47164241	1.29	DACT3	dishevelled-binding antagonist of beta-catenin 3	384	0.43
chr17_56031434_56032135	1.28	CUEDC1	CUE domain containing 1	834	0.58
chr9_140335933_140336159	1.27	ENTPD8	ectonucleoside triphosphate diphosphohydrolase 8	145	0.93
chr14_73392660_73393072	1.25	DCAF4	DDB1 and CUL4 associated factor 4	174	0.95
chr22_45404880_45405307	1.25	PHF21B	PHD finger protein 21B	219	0.95
chr11_20177941_20178449	1.24	DBX1	developing brain homeobox 1	3675	0.29
chr19_51162292_51162692	1.23	SYT3	synaptotagmin III	9159	0.12
chr18_10454407_10454669	1.22	APCDD1	adenomatosis polyposis coli down-regulated 1	87	0.98
chr19_1168901_1169806	1.21	SBNO2	strawberry notch homolog 2 (Drosophila)	411	0.76
chr17_37729625_37730222	1.21	ENSG00000222777	.	27426	0.12
chrX_152992299_152993172	1.20	ABCD1	ATP-binding cassette, sub-family D (ALD), member 1	1463	0.23
chr8_145008454_145009068	1.20	PLEC	plectin	4997	0.12
chr7_128828160_128828607	1.20	SMO	smoothened, frizzled family receptor	330	0.84
chr1_204120333_204120989	1.20	ETNK2	ethanolamine kinase 2	105	0.95
chr10_80916996_80917718	1.20	ZMIZ1	zinc finger, MIZ-type containing 1	88565	0.09
chr17_38501915_38502668	1.19	RARA	retinoic acid receptor, alpha	798	0.45
chr19_1253556_1254162	1.19	MIDN	midnolin	2238	0.14
chr6_44233364_44233515	1.19	NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	61	0.95
chr17_1388316_1388880	1.19	MYO1C	myosin IC	63	0.96
chr17_47073556_47073865	1.16	IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	1064	0.27
chr15_41785353_41785895	1.16	ITPKA	inositol-trisphosphate 3-kinase A	33	0.97
chr11_64059326_64060001	1.15	KCNK4	potassium channel, subfamily K, member 4	181	0.83
chr19_11590864_11591191	1.15	ELAVL3	ELAV like neuron-specific RNA binding protein 3	413	0.69
chr9_140189992_140190241	1.15	RP13-122B23.8		57	0.94
chr2_241759843_241760095	1.14	KIF1A	kinesin family member 1A	244	0.93
chr7_116200506_116200657	1.14	AC006159.5		8558	0.17
chr2_242711135_242711503	1.14	GAL3ST2	galactose-3-O-sulfotransferase 2	4921	0.11
chr19_41196829_41197444	1.14	NUMBL	numb homolog (Drosophila)-like	259	0.87
chr19_42573869_42574020	1.14	GRIK5	glutamate receptor, ionotropic, kainate 5	294	0.67
chr19_48674183_48675124	1.14	C19orf68	chromosome 19 open reading frame 68	704	0.32
chr7_129419053_129419592	1.14	ENSG00000207691	.	4468	0.17
chr21_15588417_15588693	1.13	RBM11	RNA binding motif protein 11	56	0.98
chr2_36608289_36608522	1.13	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	24791	0.25
chr11_65486527_65487369	1.13	KAT5	K(lysine) acetyltransferase 5	771	0.41
chr10_81206187_81206604	1.12	ZCCHC24	zinc finger, CCHC domain containing 24	1012	0.58
chr19_52192320_52192671	1.12	ENSG00000207550	.	3370	0.12
chr19_39522232_39522519	1.12	FBXO27	F-box protein 27	790	0.43
chr1_156675699_156676565	1.12	CRABP2	cellular retinoic acid binding protein 2	524	0.6
chr21_46352814_46353176	1.11	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	1091	0.32
chr19_3358525_3358748	1.11	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	925	0.58
chr17_1613463_1614162	1.11	TLCD2	TLC domain containing 2	80	0.94
chr8_144513420_144513883	1.10	MAFA	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A	1075	0.37
chr22_18958063_18958554	1.09	DGCR5	DiGeorge syndrome critical region gene 5 (non-protein coding)	212	0.93
chr8_102093028_102093564	1.09	ENSG00000202360	.	56891	0.13
chr11_119612967_119613118	1.09	CTD-2523D13.2		12749	0.2
chr8_143695048_143695766	1.09	ARC	activity-regulated cytoskeleton-associated protein	1426	0.34
chr1_3310269_3310549	1.08	PRDM16	PR domain containing 16	2646	0.34
chr9_94711281_94711744	1.08	ROR2	receptor tyrosine kinase-like orphan receptor 2	350	0.93
chr10_135043950_135044439	1.07	UTF1	undifferentiated embryonic cell transcription factor 1	416	0.76
chr19_54974776_54975134	1.07	LENG9	leukocyte receptor cluster (LRC) member 9	61	0.94
chr10_27220222_27220564	1.07	ENSG00000238414	.	63299	0.1
chr16_4378324_4378965	1.07	GLIS2	GLIS family zinc finger 2	3581	0.16
chr19_11529071_11529829	1.07	RGL3	ral guanine nucleotide dissociation stimulator-like 3	201	0.85
chr8_145489473_145489982	1.06	SCXA	scleraxis homolog A (mouse)	822	0.42
chr19_46405041_46405688	1.06	MYPOP	Myb-related transcription factor, partner of profilin	498	0.67
chr1_156477763_156478531	1.06	MEF2D	myocyte enhancer factor 2D	7527	0.12
chr21_47541509_47541660	1.05	COL6A2	collagen, type VI, alpha 2	1110	0.39
chr5_172323723_172324191	1.05	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	8263	0.19
chr20_62694983_62695936	1.04	TCEA2	transcription elongation factor A (SII), 2	19	0.95
chr2_241856355_241856511	1.04	AC104809.3	Protein LOC728763	1769	0.29
chr8_145555628_145555779	1.04	SCRT1	scratch family zinc finger 1	4240	0.08
chr9_35675902_35676521	1.04	CA9	carbonic anhydrase IX	2358	0.11
chr2_91670038_91670685	1.03	IGKV1OR2-118	immunoglobulin kappa variable 1/OR2-118 (pseudogene)	8726	0.31
chr8_140715569_140715968	1.03	KCNK9	potassium channel, subfamily K, member 9	469	0.9
chr6_3457336_3457772	1.03	SLC22A23	solute carrier family 22, member 23	298	0.94
chr13_78271609_78271760	1.02	SLAIN1	SLAIN motif family, member 1	339	0.67
chr2_10092065_10092433	1.02	GRHL1	grainyhead-like 1 (Drosophila)	422	0.85
chr3_141868395_141868983	1.02	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	303	0.9
chr15_67316146_67316685	1.02	SMAD3	SMAD family member 3	39686	0.2
chr1_156096167_156097087	1.02	LMNA	lamin A/C	33	0.96
chr22_47031263_47031414	1.01	GRAMD4	GRAM domain containing 4	8680	0.25
chr22_39638721_39639222	1.01	PDGFB	platelet-derived growth factor beta polypeptide	50	0.97
chr17_78450967_78451459	1.01	NPTX1	neuronal pentraxin I	809	0.63
chr8_99438628_99439079	1.01	KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	397	0.86
chr19_55880544_55880931	1.01	IL11	interleukin 11	128	0.89
chr11_775392_775912	1.00	PDDC1	Parkinson disease 7 domain containing 1	1584	0.14
chr9_69786015_69786709	1.00	IGKV1OR-2	immunoglobulin kappa variable 1/OR-2 (pseudogene)	8409	0.25
chr17_77752251_77752575	1.00	CBX2	chromobox homolog 2	420	0.78
chr6_36807900_36808328	1.00	CPNE5	copine V	336	0.88
chr1_23751249_23751520	0.99	TCEA3	transcription elongation factor A (SII), 3	151	0.95
chr18_8949167_8949318	0.99	RP11-674N23.4		147588	0.04
chr10_80897727_80898445	0.99	ZMIZ1	zinc finger, MIZ-type containing 1	69294	0.12
chr7_25891719_25892347	0.98	ENSG00000199085	.	97573	0.09

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SP1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.2	4.6	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.8	2.3	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.8	2.3	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.7	2.7	GO:0032329	serine transport(GO:0032329)
0.6	1.8	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.6	1.8	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.5	2.6	GO:0006020	inositol metabolic process(GO:0006020)
0.5	2.0	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.4	1.6	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.3	0.3	GO:0097205	regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.3	0.7	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.3	3.5	GO:0031581	hemidesmosome assembly(GO:0031581)
0.3	1.9	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.3	1.2	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.3	0.9	GO:1902803	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.3	0.9	GO:0042732	D-xylose metabolic process(GO:0042732)
0.3	1.1	GO:0055026	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.3	0.8	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.3	1.4	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.3	2.7	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.3	1.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	0.8	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.3	0.5	GO:0060676	ureteric bud formation(GO:0060676)
0.2	0.7	GO:0032261	purine nucleotide salvage(GO:0032261)
0.2	0.7	GO:0061072	iris morphogenesis(GO:0061072)
0.2	1.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.2	0.5	GO:0071875	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2	0.9	GO:0021894	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.2	1.4	GO:0016264	gap junction assembly(GO:0016264)
0.2	0.2	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2	0.7	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2	0.7	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.2	1.8	GO:0015671	oxygen transport(GO:0015671)
0.2	0.7	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.2	0.7	GO:0033622	integrin activation(GO:0033622)
0.2	0.7	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.2	1.1	GO:0021670	lateral ventricle development(GO:0021670)
0.2	0.8	GO:0007028	cytoplasm organization(GO:0007028)
0.2	0.6	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.2	0.6	GO:0009405	pathogenesis(GO:0009405)
0.2	0.6	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.2	0.6	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.2	1.0	GO:0008089	anterograde axonal transport(GO:0008089)
0.2	0.2	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.2	0.8	GO:0060539	diaphragm development(GO:0060539)
0.2	0.4	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.2	0.8	GO:0034063	stress granule assembly(GO:0034063)
0.2	0.6	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.2	0.6	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	0.8	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.2	1.0	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.2	0.6	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.2	0.7	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.2	0.5	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.2	0.5	GO:0003171	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.2	0.2	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.2	1.4	GO:0045176	apical protein localization(GO:0045176)
0.2	0.7	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.2	0.3	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2	0.7	GO:0043457	regulation of cellular respiration(GO:0043457)
0.2	0.9	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.2	1.2	GO:0006657	CDP-choline pathway(GO:0006657)
0.2	0.3	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.2	0.5	GO:0048548	regulation of pinocytosis(GO:0048548)
0.2	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.2	0.5	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2	0.6	GO:0015705	iodide transport(GO:0015705)
0.2	0.9	GO:0042574	retinal metabolic process(GO:0042574)
0.2	3.2	GO:0030818	negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818)
0.2	1.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.2	2.6	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.1	1.0	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.1	0.4	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	0.6	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1	0.6	GO:0043049	otic placode formation(GO:0043049)
0.1	0.4	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.1	0.4	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	1.0	GO:0010155	regulation of proton transport(GO:0010155)
0.1	0.9	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1	0.4	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	1.0	GO:0030252	growth hormone secretion(GO:0030252)
0.1	0.8	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.1	0.4	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.1	0.1	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.1	0.4	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1	0.4	GO:0060014	granulosa cell differentiation(GO:0060014)
0.1	0.6	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.4	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.1	0.3	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.1	GO:0032203	telomere formation via telomerase(GO:0032203)
0.1	0.4	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.1	1.3	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.1	0.4	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.7	GO:0021984	adenohypophysis development(GO:0021984)
0.1	0.5	GO:0072070	loop of Henle development(GO:0072070)
0.1	0.4	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.5	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.1	0.4	GO:0030321	transepithelial chloride transport(GO:0030321)
0.1	4.1	GO:0017156	calcium ion regulated exocytosis(GO:0017156)
0.1	0.4	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.1	0.1	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1	0.4	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.8	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.1	0.1	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.1	0.1	GO:0060462	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1	0.1	GO:0042117	monocyte activation(GO:0042117)
0.1	0.2	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.3	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.1	0.9	GO:0007143	female meiotic division(GO:0007143)
0.1	0.2	GO:0042268	regulation of cytolysis(GO:0042268)
0.1	0.8	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.1	0.2	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	1.3	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.1	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.2	GO:1903306	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301) negative regulation of regulated secretory pathway(GO:1903306)
0.1	0.2	GO:0046958	nonassociative learning(GO:0046958)
0.1	0.6	GO:0008088	axo-dendritic transport(GO:0008088)
0.1	0.2	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1	0.5	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.1	0.4	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.3	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.1	0.6	GO:0015840	urea transport(GO:0015840)
0.1	0.2	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1	0.3	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1	0.4	GO:0032099	negative regulation of appetite(GO:0032099)
0.1	0.2	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.1	1.0	GO:0042573	retinoic acid metabolic process(GO:0042573)
0.1	1.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.1	0.2	GO:1902170	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.1	0.2	GO:0046618	drug export(GO:0046618)
0.1	0.3	GO:0042420	dopamine catabolic process(GO:0042420)
0.1	0.4	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	0.7	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.1	0.5	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.1	2.3	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1	0.3	GO:0015879	amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879)
0.1	0.3	GO:0045007	depurination(GO:0045007)
0.1	0.3	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.1	0.8	GO:0006600	creatine metabolic process(GO:0006600)
0.1	0.2	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1	0.3	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.2	GO:0007343	egg activation(GO:0007343)
0.1	0.9	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1	0.7	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1	0.2	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1	0.3	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.1	0.2	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.2	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.1	0.3	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.1	GO:0010002	cardioblast differentiation(GO:0010002)
0.1	0.3	GO:0015919	peroxisomal membrane transport(GO:0015919)
0.1	0.2	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	0.4	GO:0061162	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1	0.2	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.4	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.2	GO:0051323	metaphase(GO:0051323)
0.1	0.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	4.0	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.1	0.3	GO:0021978	telencephalon regionalization(GO:0021978)
0.1	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.4	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.4	GO:0046541	saliva secretion(GO:0046541)
0.1	0.1	GO:0042637	catagen(GO:0042637)
0.1	0.3	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.1	0.1	GO:0072179	nephric duct formation(GO:0072179)
0.1	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.1	GO:0043173	nucleotide salvage(GO:0043173)
0.1	0.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.1	GO:0003207	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.4	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.1	0.2	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.1	0.8	GO:0046415	urate metabolic process(GO:0046415)
0.1	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.3	GO:0044803	multi-organism membrane organization(GO:0044803)
0.1	0.2	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.1	0.5	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.1	1.2	GO:0048168	regulation of neuronal synaptic plasticity(GO:0048168)
0.1	0.2	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.1	0.2	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.1	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.1	0.1	GO:1903332	regulation of protein folding(GO:1903332)
0.1	0.3	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.1	0.3	GO:0006837	serotonin transport(GO:0006837)
0.1	0.1	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.1	0.8	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.1	1.6	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.1	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.1	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.1	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.4	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.1	0.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.3	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1	0.1	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1	0.2	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.1	0.2	GO:0071398	cellular response to fatty acid(GO:0071398)
0.1	0.3	GO:0060023	soft palate development(GO:0060023)
0.1	2.1	GO:0007588	excretion(GO:0007588)
0.1	0.1	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.4	GO:0006265	DNA topological change(GO:0006265)
0.1	0.1	GO:0009299	mRNA transcription(GO:0009299)
0.1	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	0.1	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1	0.2	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.3	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.1	0.6	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1	0.3	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.1	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.1	0.4	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.1	1.3	GO:0033344	cholesterol efflux(GO:0033344)
0.1	0.2	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.2	GO:0009649	entrainment of circadian clock(GO:0009649)
0.1	0.2	GO:0005984	disaccharide metabolic process(GO:0005984)
0.1	0.2	GO:0031579	membrane raft organization(GO:0031579)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.1	GO:0035625	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.1	0.2	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.5	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.3	GO:0015871	choline transport(GO:0015871)
0.1	0.5	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1	0.3	GO:0051205	protein insertion into membrane(GO:0051205)
0.1	0.1	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1	0.3	GO:0042749	regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.1	0.1	GO:0070423	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1	0.4	GO:0032069	regulation of nuclease activity(GO:0032069)
0.1	0.2	GO:0045634	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.1	0.3	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.1	0.1	GO:0048263	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.1	0.2	GO:0007097	nuclear migration(GO:0007097)
0.1	0.4	GO:0015884	folic acid transport(GO:0015884)
0.1	0.3	GO:0045008	depyrimidination(GO:0045008)
0.0	0.6	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.2	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.8	GO:0045739	positive regulation of DNA repair(GO:0045739)
0.0	0.0	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.4	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0010996	response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0	0.2	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.2	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.2	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.2	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	1.0	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.2	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.0	GO:0060841	venous blood vessel development(GO:0060841)
0.0	0.3	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.3	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.2	GO:0001569	patterning of blood vessels(GO:0001569)
0.0	0.1	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.0	0.0	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.2	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
0.0	0.4	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.5	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.2	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.0	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0000239	pachytene(GO:0000239)
0.0	0.0	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.3	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.0	GO:1900543	negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of purine nucleotide biosynthetic process(GO:1900372) negative regulation of purine nucleotide metabolic process(GO:1900543)
0.0	0.1	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0043501	skeletal muscle adaptation(GO:0043501)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.5	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.4	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.2	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.2	GO:0051197	positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0	0.0	GO:0015697	quaternary ammonium group transport(GO:0015697)
0.0	0.0	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.0	GO:0001977	renal system process involved in regulation of blood volume(GO:0001977)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0048840	otolith development(GO:0048840)
0.0	0.2	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0001963	synaptic transmission, dopaminergic(GO:0001963)
0.0	0.2	GO:0032720	negative regulation of tumor necrosis factor production(GO:0032720) negative regulation of tumor necrosis factor superfamily cytokine production(GO:1903556)
0.0	0.2	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.1	GO:0097480	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0006282	regulation of DNA repair(GO:0006282)
0.0	0.5	GO:0000045	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.0	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.2	GO:0050901	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.2	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.1	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	0.1	GO:0016236	macroautophagy(GO:0016236)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0043691	reverse cholesterol transport(GO:0043691)
0.0	0.1	GO:0003091	renal water homeostasis(GO:0003091)
0.0	0.1	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0042752	regulation of circadian rhythm(GO:0042752)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.4	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:1903514	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.4	GO:0043462	regulation of ATPase activity(GO:0043462)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.2	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.2	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.0	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	1.1	GO:0050804	modulation of synaptic transmission(GO:0050804)
0.0	0.3	GO:0016577	histone demethylation(GO:0016577)
0.0	0.1	GO:0009415	response to water(GO:0009415)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.6	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.3	GO:0006684	sphingomyelin metabolic process(GO:0006684)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.8	GO:0007602	phototransduction(GO:0007602)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.0	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.8	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0	0.1	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.2	GO:0061462	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.1	GO:0006942	regulation of striated muscle contraction(GO:0006942)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0045980	negative regulation of nucleotide metabolic process(GO:0045980)
0.0	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.1	GO:0015695	organic cation transport(GO:0015695)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.2	GO:0046902	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.0	GO:0002579	positive regulation of antigen processing and presentation(GO:0002579)
0.0	0.2	GO:0031103	axon regeneration(GO:0031103)
0.0	0.3	GO:0006825	copper ion transport(GO:0006825)
0.0	0.0	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.4	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.0	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.2	GO:0046718	viral entry into host cell(GO:0046718)
0.0	2.3	GO:0006414	translational elongation(GO:0006414)
0.0	1.2	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.0	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.2	GO:0042438	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0	0.2	GO:0051492	regulation of stress fiber assembly(GO:0051492)
0.0	0.1	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.1	GO:0031622	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0	0.2	GO:0051310	metaphase plate congression(GO:0051310)
0.0	0.0	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.0	0.1	GO:0090398	cellular senescence(GO:0090398)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.1	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	2.6	GO:0006813	potassium ion transport(GO:0006813)
0.0	0.0	GO:0042159	lipoprotein catabolic process(GO:0042159)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.0	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.0	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0007004	telomere maintenance via telomerase(GO:0007004)
0.0	0.1	GO:0015682	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.1	GO:0030811	regulation of nucleotide catabolic process(GO:0030811)
0.0	0.0	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis(GO:0060664)
0.0	0.1	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.0	GO:0006301	postreplication repair(GO:0006301)
0.0	0.0	GO:0006907	pinocytosis(GO:0006907)
0.0	0.0	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.3	GO:0016101	retinoid metabolic process(GO:0001523) diterpenoid metabolic process(GO:0016101)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.4	GO:0006801	superoxide metabolic process(GO:0006801)
0.0	0.0	GO:0030432	peristalsis(GO:0030432)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0042559	pteridine-containing compound biosynthetic process(GO:0042559)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.2	GO:0009268	response to pH(GO:0009268)
0.0	0.4	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.5	GO:0000725	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0	0.1	GO:0003341	cilium movement(GO:0003341)
0.0	0.1	GO:0032651	regulation of interleukin-1 beta production(GO:0032651)
0.0	0.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.1	GO:0097354	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.2	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.0	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.0	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.0	GO:0051552	flavone metabolic process(GO:0051552)
0.0	0.0	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.0	0.0	GO:0050748	negative regulation of lipoprotein metabolic process(GO:0050748)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.0	GO:0002701	negative regulation of production of molecular mediator of immune response(GO:0002701)
0.0	0.0	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.0	GO:1902624	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0	0.3	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0	0.0	GO:0071624	positive regulation of granulocyte chemotaxis(GO:0071624)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.2	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:0043243	positive regulation of protein complex disassembly(GO:0043243)
0.0	0.4	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.0	GO:0019730	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0008272	sulfate transport(GO:0008272)
0.0	0.2	GO:0030317	sperm motility(GO:0030317)
0.0	0.0	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.2	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.1	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.3	GO:0070830	bicellular tight junction assembly(GO:0070830)
0.0	0.0	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.0	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0006863	purine nucleobase transport(GO:0006863)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.0	GO:0036230	granulocyte activation(GO:0036230)
0.0	0.0	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.0	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.0	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.0	GO:0051006	positive regulation of lipoprotein lipase activity(GO:0051006) positive regulation of triglyceride lipase activity(GO:0061365)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.0	GO:0043302	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.0	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.0	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.0	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0	0.1	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.0	GO:0043324	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.0	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.0	GO:0030858	positive regulation of epithelial cell differentiation(GO:0030858)
0.0	0.0	GO:0046968	peptide antigen transport(GO:0046968)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0048485	sympathetic nervous system development(GO:0048485)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.9	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4	1.6	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3	1.0	GO:0043260	laminin-11 complex(GO:0043260)
0.3	0.9	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.3	1.1	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.3	0.3	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.3	1.0	GO:0005638	lamin filament(GO:0005638)
0.2	0.7	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.2	0.4	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.2	1.9	GO:0035253	ciliary rootlet(GO:0035253)
0.2	1.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2	1.0	GO:0000791	euchromatin(GO:0000791)
0.2	0.6	GO:0032449	CBM complex(GO:0032449)
0.2	0.6	GO:0070852	cell body fiber(GO:0070852)
0.2	0.9	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.2	2.1	GO:0005833	hemoglobin complex(GO:0005833)
0.2	1.0	GO:0005581	collagen trimer(GO:0005581)
0.2	0.7	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	0.5	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.2	1.3	GO:0002102	podosome(GO:0002102)
0.2	0.8	GO:0070695	FHF complex(GO:0070695)
0.2	1.7	GO:0031941	filamentous actin(GO:0031941)
0.2	0.5	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.2	1.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	0.7	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.8	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.3	GO:0032432	actin filament bundle(GO:0032432)
0.1	0.9	GO:0008091	spectrin(GO:0008091)
0.1	0.4	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.1	0.4	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.4	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	2.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	0.9	GO:0016342	catenin complex(GO:0016342)
0.1	0.2	GO:0070083	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1	0.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	1.9	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.1	0.3	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	0.4	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.5	GO:0042587	glycogen granule(GO:0042587)
0.1	1.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.7	GO:0043256	laminin complex(GO:0043256)
0.1	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	1.2	GO:0034706	sodium channel complex(GO:0034706)
0.1	0.3	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	1.4	GO:0030137	COPI-coated vesicle(GO:0030137)
0.1	0.7	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	0.4	GO:0043034	costamere(GO:0043034)
0.1	0.3	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.5	GO:0000125	PCAF complex(GO:0000125)
0.1	0.2	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	0.3	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.3	GO:0001740	Barr body(GO:0001740)
0.1	0.2	GO:0070545	PeBoW complex(GO:0070545)
0.1	1.3	GO:0008023	transcription elongation factor complex(GO:0008023)
0.1	1.3	GO:0005922	connexon complex(GO:0005922)
0.1	1.2	GO:0042641	actomyosin(GO:0042641)
0.1	0.9	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	0.2	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.2	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.1	0.5	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.6	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	1.1	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	0.2	GO:0030312	external encapsulating structure(GO:0030312)
0.1	4.6	GO:0060076	excitatory synapse(GO:0060076)
0.1	4.3	GO:0008021	synaptic vesicle(GO:0008021)
0.1	3.4	GO:0005604	basement membrane(GO:0005604)
0.1	0.3	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	0.2	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	0.9	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.5	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	0.2	GO:0042629	mast cell granule(GO:0042629)
0.1	0.2	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.3	GO:0005883	neurofilament(GO:0005883)
0.1	5.2	GO:0005925	focal adhesion(GO:0005925)
0.1	0.8	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1	1.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.1	1.1	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.1	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.7	GO:0031201	SNARE complex(GO:0031201)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	0.0	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.9	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.7	GO:0032420	stereocilium(GO:0032420)
0.0	0.6	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.4	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	1.5	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.3	GO:0001741	XY body(GO:0001741)
0.0	0.3	GO:0042627	chylomicron(GO:0042627)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	8.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.5	GO:0005902	microvillus(GO:0005902)
0.0	0.2	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.9	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.2	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0044453	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.8	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.3	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	2.6	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	1.9	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.4	GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.9	GO:0036477	somatodendritic compartment(GO:0036477)
0.0	0.2	GO:0043195	terminal bouton(GO:0043195)
0.0	0.6	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.6	GO:0005796	Golgi lumen(GO:0005796)
0.0	1.0	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	2.2	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	2.7	GO:0043025	neuronal cell body(GO:0043025)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.4	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.7	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	0.3	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0	1.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.3	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	2.3	GO:0045202	synapse(GO:0045202)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.0	GO:0044306	neuron projection terminus(GO:0044306)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0071565	nBAF complex(GO:0071565)
0.0	0.2	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	2.4	GO:0045111	intermediate filament cytoskeleton(GO:0045111)
0.0	0.2	GO:0097525	spliceosomal snRNP complex(GO:0097525)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0031672	A band(GO:0031672)
0.0	0.4	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.0	GO:0044297	cell body(GO:0044297)
0.0	0.5	GO:0015934	large ribosomal subunit(GO:0015934)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.0	GO:0030904	retromer complex(GO:0030904)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	5.0	GO:0004111	creatine kinase activity(GO:0004111)
0.7	2.0	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.6	1.9	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.6	1.8	GO:0070324	thyroid hormone binding(GO:0070324)
0.6	1.7	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.6	1.7	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.5	2.6	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.4	1.2	GO:0004103	choline kinase activity(GO:0004103)
0.4	1.5	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.3	1.0	GO:0004461	lactose synthase activity(GO:0004461)
0.3	2.4	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.3	3.4	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.3	0.9	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3	0.9	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.3	1.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.3	1.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.3	0.8	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3	2.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	1.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2	1.6	GO:0030506	ankyrin binding(GO:0030506)
0.2	0.9	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2	2.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	0.7	GO:0016362	activin receptor activity, type II(GO:0016362)
0.2	1.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.2	1.3	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.2	0.6	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.2	1.6	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.2	0.8	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.2	1.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.2	1.7	GO:0015643	toxic substance binding(GO:0015643)
0.2	0.6	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.2	1.3	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2	3.8	GO:0003746	translation elongation factor activity(GO:0003746)
0.2	0.5	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.2	0.5	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2	2.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.2	0.7	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.2	1.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.2	0.5	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.2	1.7	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.2	0.5	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.2	0.5	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.2	0.7	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2	0.7	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.2	0.3	GO:0048018	receptor agonist activity(GO:0048018)
0.2	1.6	GO:0017075	syntaxin-1 binding(GO:0017075)
0.2	0.5	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2	0.8	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.2	0.5	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.2	0.5	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.1	0.6	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.6	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.4	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.1	0.4	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.1	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	1.7	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	1.0	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	1.4	GO:0019841	retinol binding(GO:0019841)
0.1	0.9	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.4	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1	0.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	1.8	GO:0019894	kinesin binding(GO:0019894)
0.1	0.4	GO:0043495	protein anchor(GO:0043495)
0.1	0.2	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	0.5	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	1.4	GO:0004016	adenylate cyclase activity(GO:0004016)
0.1	0.3	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	1.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	0.5	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.3	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.3	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	0.5	GO:0034452	dynactin binding(GO:0034452)
0.1	0.4	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.4	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1	0.3	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.1	1.0	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.6	GO:0031491	nucleosome binding(GO:0031491)
0.1	0.3	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.3	GO:0031849	olfactory receptor binding(GO:0031849)
0.1	0.3	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.2	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.2	GO:0035198	miRNA binding(GO:0035198)
0.1	0.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.2	GO:0008518	reduced folate carrier activity(GO:0008518)
0.1	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	0.2	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.1	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.1	0.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.3	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1	0.2	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.1	0.7	GO:0005123	death receptor binding(GO:0005123)
0.1	1.1	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.1	0.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.1	0.3	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.1	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.1	0.6	GO:0030332	cyclin binding(GO:0030332)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.6	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.2	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.5	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.2	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1	0.4	GO:0046790	virion binding(GO:0046790)
0.1	0.3	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.1	0.8	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	0.4	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.7	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	1.0	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	0.1	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1	0.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.4	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.2	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.6	GO:0017091	AU-rich element binding(GO:0017091)
0.1	0.7	GO:0005109	frizzled binding(GO:0005109)
0.1	0.3	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	0.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.1	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1	0.8	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.1	0.2	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.1	8.6	GO:0008083	growth factor activity(GO:0008083)
0.1	1.2	GO:0035064	methylated histone binding(GO:0035064)
0.1	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	1.0	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.5	GO:0005112	Notch binding(GO:0005112)
0.1	0.5	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.1	0.2	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.1	0.2	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.3	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1	1.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.1	0.2	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.2	GO:0050897	cobalt ion binding(GO:0050897)
0.1	0.6	GO:0008430	selenium binding(GO:0008430)
0.1	0.6	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	0.4	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.1	0.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.4	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1	0.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.9	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.1	0.4	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.1	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.3	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.3	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.2	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.4	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.5	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.0	0.7	GO:0005501	retinoid binding(GO:0005501)
0.0	0.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.2	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.3	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.4	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.2	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.5	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	1.5	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	0.4	GO:0010851	cyclase regulator activity(GO:0010851)
0.0	1.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	1.1	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.2	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.7	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.4	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.2	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.3	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	4.7	GO:0005267	potassium channel activity(GO:0005267)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	3.1	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.4	GO:0005542	folic acid binding(GO:0005542)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	1.3	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.3	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.5	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.1	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.4	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.5	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.0	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.3	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.7	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0030345	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	1.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.4	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.5	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.2	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.2	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.2	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.3	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.2	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	2.5	GO:0003774	motor activity(GO:0003774)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.3	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.3	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.1	GO:0046977	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0016248	channel inhibitor activity(GO:0016248)
0.0	0.1	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	0.1	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.4	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	1.4	GO:0005088	Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0	1.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.0	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.0	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.0	GO:0004803	transposase activity(GO:0004803)
0.0	0.0	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.0	GO:0004675	transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0	0.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.3	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.0	GO:0031420	alkali metal ion binding(GO:0031420)
0.0	0.0	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.3	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.6	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.0	1.2	GO:0004386	helicase activity(GO:0004386)
0.0	0.0	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.1	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.0	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.0	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.0	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.0	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.0	0.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.0	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	0.5	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.2	1.9	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	4.0	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.2	4.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.2	2.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	1.0	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	1.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	0.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	4.7	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	0.4	PID EPO PATHWAY	EPO signaling pathway
0.1	0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.1	0.4	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.5	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	0.3	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.1	3.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	1.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	2.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	1.2	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.1	0.6	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	1.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	0.9	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.2	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.5	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.5	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	1.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.9	PID MYC PATHWAY	C-MYC pathway
0.0	1.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	6.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.5	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	1.7	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.6	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	5.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.0	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	1.1	PID E2F PATHWAY	E2F transcription factor network
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	6.4	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.2	PID ATR PATHWAY	ATR signaling pathway
0.0	0.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.3	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	2.7	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0	0.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.1	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	0.4	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.2	2.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.2	1.8	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	1.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	1.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	2.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	1.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	2.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	1.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.8	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	1.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	2.0	REACTOME KINESINS	Genes involved in Kinesins
0.1	2.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	0.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	0.7	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	1.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	0.1	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	1.0	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.1	2.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	0.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	1.7	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	0.8	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	0.8	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	1.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	2.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	0.7	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	0.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	0.6	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.1	1.0	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1	0.6	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.1	1.0	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	2.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.4	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.8	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0	0.4	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.7	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.7	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.5	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	1.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.9	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.3	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.7	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	2.8	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.4	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.1	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.4	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.2	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.3	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.2	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0	0.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.6	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.4	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.3	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	3.5	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.5	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.1	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.1	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.5	REACTOME TRANSLATION	Genes involved in Translation
0.0	1.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.8	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition