Results for SPDEF

Z-value: 0.29

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Transcription factors associated with SPDEF

Gene Symbol	Gene ID	Gene Info
SPDEF Ensembl NCBI GeneCards UniProt	ENSG00000124664.6	SAM pointed domain containing ETS transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_34522202_34522430	SPDEF	1775	0.363801	0.86	2.7e-03	Click!
chr6_34563292_34563443	SPDEF	39257	0.128293	-0.74	2.2e-02	Click!
chr6_34522519_34522670	SPDEF	1497	0.414186	0.56	1.2e-01	Click!
chr6_34570627_34570778	SPDEF	46592	0.110161	-0.48	1.9e-01	Click!
chr6_34559862_34560013	SPDEF	35827	0.137005	-0.41	2.7e-01	Click!

Activity of the SPDEF motif across conditions

Conditions sorted by the z-value of the SPDEF motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr20_12035730_12035893	0.14	BTBD3	BTB (POZ) domain containing 3	136312	0.05
chr20_5467721_5467872	0.13	RP5-1022P6.5		46478	0.16
chr8_103569195_103569346	0.10	ODF1	outer dense fiber of sperm tails 1	3420	0.23
chr17_56082572_56082977	0.08	RP11-159D12.5	Uncharacterized protein	160	0.93
chr11_70333823_70333974	0.08	AP001271.3		10201	0.17
chr1_15502978_15503129	0.08	C1orf195	chromosome 1 open reading frame 195	5240	0.23
chr16_49497686_49497886	0.08	C16orf78	chromosome 16 open reading frame 78	90052	0.09
chr8_8710372_8710647	0.07	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	40646	0.15
chr20_44037455_44037675	0.07	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2	636	0.57
chr7_70879519_70879670	0.07	ENSG00000266688	.	104057	0.07
chr6_139435997_139436148	0.06	HECA	headcase homolog (Drosophila)	20177	0.23
chr8_135700059_135700229	0.06	ZFAT	zinc finger and AT hook domain containing	8653	0.29
chr14_25143389_25143852	0.06	GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	40147	0.14
chr7_79780099_79780250	0.06	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	15103	0.27
chr7_99097504_99097655	0.06	ZNF394	zinc finger protein 394	308	0.8
chr12_52294891_52295042	0.06	ACVRL1	activin A receptor type II-like 1	5726	0.18
chr1_39572189_39572340	0.06	MACF1	microtubule-actin crosslinking factor 1	1181	0.46
chr19_10677060_10677233	0.06	KRI1	KRI1 homolog (S. cerevisiae)	433	0.66
chr21_43923846_43924117	0.05	SLC37A1	solute carrier family 37 (glucose-6-phosphate transporter), member 1	4239	0.15
chr6_16840168_16840368	0.05	RP1-151F17.1		78125	0.11
chr1_116012997_116013148	0.05	ENSG00000265534	.	15200	0.26
chr1_9967558_9967806	0.05	CTNNBIP1	catenin, beta interacting protein 1	2639	0.19
chr15_38543912_38544094	0.05	SPRED1	sprouty-related, EVH1 domain containing 1	524	0.88
chr15_90920320_90920549	0.05	IQGAP1	IQ motif containing GTPase activating protein 1	11016	0.13
chr1_25197627_25197856	0.05	RUNX3	runt-related transcription factor 3	57871	0.12
chr9_130473290_130473644	0.04	C9orf117	chromosome 9 open reading frame 117	702	0.5
chr9_102195882_102196042	0.04	ENSG00000222337	.	149658	0.04
chr2_240243457_240243608	0.04	HDAC4	histone deacetylase 4	12625	0.17
chr16_70833030_70833207	0.04	VAC14	Vac14 homolog (S. cerevisiae)	1946	0.3
chr5_40409894_40410067	0.04	ENSG00000265615	.	89560	0.09
chr8_15397733_15397884	0.04	TUSC3	tumor suppressor candidate 3	16	0.99
chr12_109094894_109095192	0.04	CORO1C	coronin, actin binding protein, 1C	89	0.96
chr3_121556181_121556332	0.04	EAF2	ELL associated factor 2	2172	0.26
chr14_52486773_52486924	0.04	NID2	nidogen 2 (osteonidogen)	18822	0.15
chr9_90184496_90184647	0.04	DAPK1-IT1	DAPK1 intronic transcript 1 (non-protein coding)	16202	0.25
chr20_1368756_1368928	0.04	FKBP1A	FK506 binding protein 1A, 12kDa	4764	0.17
chr1_38381642_38381793	0.04	INPP5B	inositol polyphosphate-5-phosphatase, 75kDa	15704	0.12
chr11_67176002_67176390	0.04	TBC1D10C	TBC1 domain family, member 10C	4536	0.08
chr6_114663139_114663290	0.04	HS3ST5	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	995	0.64
chr2_43154939_43155091	0.04	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	135283	0.05
chr4_84309456_84309609	0.04	HPSE	heparanase	53226	0.12
chr4_93226237_93226388	0.04	GRID2	glutamate receptor, ionotropic, delta 2	504	0.7
chr1_119544701_119544852	0.04	TBX15	T-box 15	12597	0.25
chr2_99348992_99349150	0.04	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	1482	0.47
chr2_75067357_75067724	0.04	HK2	hexokinase 2	5243	0.28
chr8_74960620_74960771	0.04	ENSG00000212348	.	217	0.93
chr11_67414259_67414491	0.04	ACY3	aspartoacylase (aminocyclase) 3	679	0.53
chr17_80936346_80936497	0.03	RP11-1197K16.2		20	0.98
chr6_3906199_3906350	0.03	FAM50B	family with sequence similarity 50, member B	56652	0.11
chr16_27237902_27238131	0.03	NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	6383	0.17
chr16_990647_990798	0.03	LMF1	lipase maturation factor 1	6922	0.12
chr11_32448179_32448330	0.03	WT1	Wilms tumor 1	2321	0.35
chr1_42174975_42175158	0.03	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	8394	0.27
chr7_99638202_99638474	0.03	ZSCAN21	zinc finger and SCAN domain containing 21	9052	0.08
chrX_54815606_54815757	0.03	ITIH6	inter-alpha-trypsin inhibitor heavy chain family, member 6	8992	0.19
chr15_89949793_89949952	0.03	ENSG00000207819	.	38624	0.14
chr9_137277437_137277619	0.03	ENSG00000263897	.	6271	0.25
chr17_43422781_43422936	0.03	ENSG00000199953	.	17995	0.13
chr14_77387324_77387558	0.03	ENSG00000223174	.	30835	0.16
chr22_41399132_41399283	0.03	ENSG00000222698	.	42294	0.1
chr3_101798103_101798306	0.03	ZPLD1	zona pellucida-like domain containing 1	19884	0.27
chr17_76129901_76130270	0.03	TMC6	transmembrane channel-like 6	1597	0.24
chr14_35884998_35885149	0.03	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	11121	0.26
chr1_93456344_93456726	0.03	ENSG00000238787	.	8670	0.12
chr12_133052067_133052443	0.03	MUC8	mucin 8	1529	0.42
chr17_55494970_55495121	0.03	ENSG00000263902	.	5483	0.29
chr5_170815611_170815762	0.03	NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	801	0.52
chr20_56811751_56811920	0.03	PPP4R1L	protein phosphatase 4, regulatory subunit 1-like	3769	0.24
chr11_63719762_63720286	0.03	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit	13304	0.1
chr15_75323561_75323712	0.03	PPCDC	phosphopantothenoylcysteine decarboxylase	3046	0.2
chr1_227177000_227177204	0.03	RP5-1087E8.3		2739	0.29
chr17_58240224_58240375	0.03	CA4	carbonic anhydrase IV	4830	0.2
chr9_35619211_35619764	0.03	CD72	CD72 molecule	52	0.94
chr22_31477423_31477574	0.03	SMTN	smoothelin	193	0.9
chr2_172067391_172067542	0.03	TLK1	tousled-like kinase 1	20358	0.24
chr5_56205875_56206117	0.03	SETD9	SET domain containing 9	64	0.89
chr13_41929969_41930120	0.02	ENSG00000223280	.	1249	0.48
chr13_42857671_42857822	0.02	AKAP11	A kinase (PRKA) anchor protein 11	11457	0.28
chr11_108108099_108108300	0.02	ENSG00000206967	.	7868	0.16
chrX_146993080_146993231	0.02	ENSG00000268066	.	180	0.66
chr3_124369409_124369560	0.02	KALRN	kalirin, RhoGEF kinase	13540	0.2
chr12_53496668_53496910	0.02	SOAT2	sterol O-acyltransferase 2	513	0.66
chr12_45912462_45912722	0.02	ENSG00000239178	.	35850	0.23
chr5_126323821_126324048	0.02	MARCH3	membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase	42566	0.18
chr9_140197836_140197987	0.02	NRARP	NOTCH-regulated ankyrin repeat protein	1208	0.28
chr2_48116267_48116418	0.02	FBXO11	F-box protein 11	484	0.84
chr16_27378848_27379069	0.02	IL4R	interleukin 4 receptor	14962	0.19
chr14_34442775_34442926	0.02	ENSG00000265244	.	3747	0.28
chr6_15411995_15412149	0.02	JARID2	jumonji, AT rich interactive domain 2	10983	0.26
chr3_194877113_194877264	0.02	XXYLT1-AS2	XXYLT1 antisense RNA 2	8568	0.15
chr15_68038905_68039209	0.02	SKOR1	SKI family transcriptional corepressor 1	72985	0.11
chr2_172511944_172512268	0.02	DYNC1I2	dynein, cytoplasmic 1, intermediate chain 2	31813	0.19
chr16_56643699_56643850	0.02	MT2A	metallothionein 2A	1256	0.23
chr14_75643741_75643916	0.02	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	494	0.76
chr7_50428693_50429337	0.02	IKZF1	IKAROS family zinc finger 1 (Ikaros)	61770	0.12
chr3_71100462_71100714	0.02	FOXP1	forkhead box P1	13489	0.3
chr8_66948642_66948793	0.02	DNAJC5B	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	6995	0.29
chr2_115409559_115409710	0.02	DPP10-AS3	DPP10 antisense RNA 3	181491	0.03
chr3_12706048_12706240	0.02	RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	419	0.85
chr7_18329482_18329633	0.02	HDAC9	histone deacetylase 9	158	0.97
chr19_6967649_6967800	0.02	RP11-1137G4.3		14502	0.13
chr3_71049205_71049356	0.02	FOXP1	forkhead box P1	64797	0.14
chr6_12483862_12484271	0.02	ENSG00000223321	.	77053	0.12
chr15_50551480_50551957	0.02	HDC	histidine decarboxylase	3908	0.18
chr2_191744058_191744209	0.02	GLS	glutaminase	1420	0.42
chr8_104090298_104090477	0.02	ENSG00000265667	.	14562	0.14
chr10_33944045_33944360	0.02	NRP1	neuropilin 1	319012	0.01
chr4_88937632_88937783	0.02	PKD2	polycystic kidney disease 2 (autosomal dominant)	8887	0.19
chr12_89199855_89200006	0.02	ENSG00000252850	.	224514	0.02
chr20_44562919_44563070	0.02	PCIF1	PDX1 C-terminal inhibiting factor 1	273	0.84
chr2_160919170_160919622	0.02	PLA2R1	phospholipase A2 receptor 1, 180kDa	275	0.95
chr16_81751684_81751835	0.02	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	20943	0.25
chr1_92831597_92831748	0.02	ENSG00000242764	.	36570	0.16
chr5_6687078_6687333	0.02	PAPD7	PAP associated domain containing 7	27513	0.2
chr20_18559538_18559689	0.02	DTD1	D-tyrosyl-tRNA deacylase 1	8924	0.14
chr1_8021220_8021371	0.02	PARK7	parkinson protein 7	428	0.82
chr16_47677756_47678055	0.02	PHKB	phosphorylase kinase, beta	16709	0.26
chr11_88091283_88091499	0.02	CTSC	cathepsin C	20436	0.27
chr4_38807003_38807325	0.02	TLR1	toll-like receptor 1	35	0.97
chr8_55366934_55367085	0.02	SOX17	SRY (sex determining region Y)-box 17	3486	0.31
chr1_233100462_233100613	0.02	NTPCR	nucleoside-triphosphatase, cancer-related	14151	0.27
chr1_120643812_120643963	0.02	ENSG00000207149	.	25675	0.2
chr1_228328808_228329114	0.02	GUK1	guanylate kinase 1	122	0.93
chr3_176892306_176892651	0.02	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	21733	0.21
chr12_90103924_90104204	0.02	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	987	0.58
chr13_113446403_113446554	0.02	ATP11A	ATPase, class VI, type 11A	6992	0.22
chr3_119043058_119043230	0.02	ARHGAP31	Rho GTPase activating protein 31	595	0.64
chr20_2709979_2710148	0.02	EBF4	early B-cell factor 4	23176	0.11
chr5_154140499_154140846	0.02	LARP1	La ribonucleoprotein domain family, member 1	3938	0.22
chr20_62078021_62078172	0.02	RP11-358D14.2		1308	0.34
chr14_59775622_59775784	0.02	DAAM1	dishevelled associated activator of morphogenesis 1	45530	0.17
chr8_38642282_38642433	0.02	TACC1	transforming, acidic coiled-coil containing protein 1	835	0.61
chr2_207971459_207971636	0.02	ENSG00000253008	.	3250	0.25
chr2_1746792_1747088	0.02	PXDN	peroxidasin homolog (Drosophila)	1274	0.58
chr6_44990362_44990513	0.02	SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	67190	0.14
chr16_73071069_73071220	0.02	ZFHX3	zinc finger homeobox 3	11130	0.21
chr2_86088819_86089093	0.02	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	5821	0.2
chr17_42581041_42581192	0.02	GPATCH8	G patch domain containing 8	318	0.89
chr6_140693241_140693392	0.02	ENSG00000263514	.	166927	0.04
chr11_134200957_134201334	0.02	GLB1L2	galactosidase, beta 1-like 2	623	0.74
chr17_4934338_4934489	0.02	SLC52A1	solute carrier family 52 (riboflavin transporter), member 1	4308	0.09
chr14_104026251_104026422	0.02	KLC1	kinesin light chain 1	1897	0.13
chr16_88577974_88578125	0.02	RP11-21B21.4		19412	0.15
chr5_159852646_159852968	0.02	PTTG1	pituitary tumor-transforming 1	3890	0.17
chr17_15160854_15161162	0.02	RP11-849N15.1		3324	0.18
chr1_26699943_26700094	0.02	ZNF683	zinc finger protein 683	752	0.53
chr19_4909695_4909846	0.02	ARRDC5	arrestin domain containing 5	6891	0.13
chr22_39513310_39513588	0.02	APOBEC3H	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H	20169	0.12
chr2_97220347_97220506	0.02	ARID5A	AT rich interactive domain 5A (MRF1-like)	17344	0.17
chr15_59883398_59883549	0.02	GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type	8403	0.16
chr2_220112619_220112770	0.02	STK16	serine/threonine kinase 16	2076	0.12
chr7_73684094_73684487	0.02	ENSG00000252538	.	11344	0.16
chr2_86081314_86081925	0.02	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	13158	0.17
chr1_63590553_63590704	0.02	ENSG00000252259	.	61493	0.14
chr8_66720311_66720463	0.02	PDE7A	phosphodiesterase 7A	19068	0.25
chr3_136651549_136651717	0.02	NCK1	NCK adaptor protein 1	2289	0.3
chr22_42720993_42721144	0.02	TCF20	transcription factor 20 (AR1)	18554	0.21
chr16_881238_881389	0.02	PRR25	proline rich 25	25870	0.08
chr19_46456155_46456430	0.02	NOVA2	neuro-oncological ventral antigen 2	9572	0.12
chr9_130823428_130823579	0.02	RP11-379C10.1		3862	0.12
chr19_9947103_9947290	0.01	PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	1179	0.27
chr1_55677009_55677515	0.01	USP24	ubiquitin specific peptidase 24	3500	0.28
chr18_29226272_29226561	0.01	ENSG00000252379	.	22925	0.14
chr9_38178862_38179013	0.01	ENSG00000238313	.	11467	0.23
chr15_52519948_52520099	0.01	GNB5	guanine nucleotide binding protein (G protein), beta 5	36457	0.13
chr3_105087659_105088022	0.01	ALCAM	activated leukocyte cell adhesion molecule	1653	0.56
chr5_156644620_156644840	0.01	CTB-4E7.1		6660	0.14
chr8_105526206_105526448	0.01	LRP12	low density lipoprotein receptor-related protein 12	16494	0.18
chr5_140762395_140762546	0.01	PCDHGA7	protocadherin gamma subfamily A, 7	3	0.92
chr15_91124407_91124901	0.01	CRTC3	CREB regulated transcription coactivator 3	12291	0.16
chr2_43102794_43102945	0.01	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	83137	0.1
chr7_45065735_45065994	0.01	CCM2	cerebral cavernous malformation 2	761	0.59
chr5_7858135_7858623	0.01	C5orf49	chromosome 5 open reading frame 49	6776	0.2
chr5_163791498_163791649	0.01	CTC-340A15.2		10414	0.33
chr1_65472844_65472995	0.01	ENSG00000212257	.	15838	0.19
chr11_22802628_22802929	0.01	RP11-17A1.3		48148	0.13
chr14_23341967_23342255	0.01	LRP10	low density lipoprotein receptor-related protein 10	598	0.5
chr13_91922505_91922656	0.01	ENSG00000215417	.	80279	0.12
chr22_32548036_32548187	0.01	C22orf42	chromosome 22 open reading frame 42	7164	0.15
chr12_47670226_47670510	0.01	RP11-493L12.3		2436	0.33
chr4_78508156_78508528	0.01	CXCL13	chemokine (C-X-C motif) ligand 13	75435	0.11
chr19_10909004_10909246	0.01	DNM2	dynamin 2	15433	0.11
chr15_48625727_48625878	0.01	DUT	deoxyuridine triphosphatase	1199	0.39
chr6_158185608_158185759	0.01	SNX9	sorting nexin 9	58613	0.12
chr11_122546290_122546441	0.01	UBASH3B	ubiquitin associated and SH3 domain containing B	19982	0.22
chr1_16705960_16706111	0.01	SZRD1	SUZ RNA binding domain containing 1	12275	0.15
chr3_190331803_190331954	0.01	IL1RAP	interleukin 1 receptor accessory protein	1219	0.57
chr5_131862715_131862951	0.01	IL5	interleukin 5 (colony-stimulating factor, eosinophil)	16381	0.13
chr1_244248428_244248579	0.01	ENSG00000244066	.	18731	0.19
chr5_173886992_173887281	0.01	MSX2	msh homeobox 2	264400	0.02
chr21_35942712_35942925	0.01	RCAN1	regulator of calcineurin 1	10341	0.23
chr1_208136086_208136376	0.01	CD34	CD34 molecule	51484	0.18
chr19_14444085_14444306	0.01	CD97	CD97 molecule	47773	0.1
chr9_135764417_135764672	0.01	C9orf9	chromosome 9 open reading frame 9	10259	0.13
chr14_38594881_38595032	0.01	CTD-2058B24.2		34593	0.19
chr11_58776578_58776729	0.01	RP11-142C4.6		29895	0.16
chr1_38476222_38476373	0.01	UTP11L	UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)	2117	0.21
chr1_111422898_111423185	0.01	CD53	CD53 molecule	7265	0.2
chr15_68122450_68122601	0.01	SKOR1	SKI family transcriptional corepressor 1	4584	0.27
chr15_64793933_64794220	0.01	ZNF609	zinc finger protein 609	2585	0.24