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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for SPIB

Z-value: 4.55

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Transcription factors associated with SPIB

Gene Symbol	Gene ID	Gene Info
SPIB Ensembl NCBI GeneCards UniProt	ENSG00000269404.2	Spi-B transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr19_50921586_50921737	SPIB	534	0.565516	0.48	1.9e-01	Click!
chr19_50922313_50922464	SPIB	173	0.881385	0.47	2.0e-01	Click!
chr19_50921921_50922072	SPIB	199	0.861269	0.31	4.2e-01	Click!
chr19_50923202_50923353	SPIB	1062	0.299900	0.20	6.0e-01	Click!
chr19_50922673_50922824	SPIB	533	0.575121	-0.02	9.7e-01	Click!

Activity of the SPIB motif across conditions

Conditions sorted by the z-value of the SPIB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_72129424_72129793	1.94	ENSG00000212070	.	181971	0.03
chr6_51778152_51778400	1.84	ENSG00000240641	.	62182	0.14
chr12_110435362_110435658	1.61	GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	1316	0.37
chr5_127175889_127176216	1.45	CTC-548H10.2		176331	0.03
chr12_11748797_11749209	1.44	ENSG00000251747	.	49590	0.13
chr8_96059416_96059642	1.42	ENSG00000200525	.	7913	0.16
chr11_61690283_61690510	1.39	RAB3IL1	RAB3A interacting protein (rabin3)-like 1	2655	0.18
chr4_124154726_124155069	1.33	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	163053	0.04
chr7_33091034_33091380	1.33	ENSG00000241420	.	5505	0.17
chr4_75955696_75956116	1.31	RP11-44F21.2		4128	0.31
chr17_29281218_29281504	1.29	AC091177.1		2618	0.14
chr7_141628504_141628805	1.29	OR9A4	olfactory receptor, family 9, subfamily A, member 4	10037	0.12
chr1_202957021_202957552	1.26	RP11-38O14.5		424	0.76
chr12_66192615_66192775	1.24	HMGA2	high mobility group AT-hook 2	25216	0.2
chr1_64978255_64978644	1.22	CACHD1	cache domain containing 1	41974	0.18
chr3_16006227_16006629	1.21	ENSG00000207815	.	91150	0.08
chr1_21276786_21277018	1.20	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	8791	0.23
chr22_38438083_38438604	1.19	RP5-1039K5.16		8108	0.11
chr6_116950762_116950913	1.18	RSPH4A	radial spoke head 4 homolog A (Chlamydomonas)	13050	0.16
chr1_244409811_244410006	1.18	C1orf100	chromosome 1 open reading frame 100	106029	0.07
chr6_135746178_135746329	1.17	AHI1	Abelson helper integration site 1	13607	0.24
chr14_65509694_65510092	1.15	ENSG00000266531	.	1513	0.32
chr2_43460695_43460846	1.12	AC010883.5		4058	0.27
chr4_106079913_106080064	1.10	TET2	tet methylcytosine dioxygenase 2	11374	0.21
chr11_59831605_59831852	1.09	MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)	3094	0.24
chr12_58268045_58268317	1.09	CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	27659	0.1
chr2_137011178_137011329	1.08	CXCR4	chemokine (C-X-C motif) receptor 4	135518	0.05
chr15_71099407_71099754	1.03	RP11-138H8.3		28373	0.14
chr2_65068622_65068773	1.03	ENSG00000199964	.	7406	0.19
chr22_43199771_43199922	1.02	ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	27812	0.17
chr1_116525009_116525247	1.02	SLC22A15	solute carrier family 22, member 15	5893	0.26
chr17_57062744_57062920	1.01	ENSG00000216168	.	3483	0.2
chr4_183795369_183795572	1.00	DCTD	dCMP deaminase	42310	0.16
chr9_126503669_126503820	0.99	RP11-417B4.2		5028	0.3
chr14_69519109_69519260	0.98	ACTN1-AS1	ACTN1 antisense RNA 1	72426	0.09
chr20_48321244_48321782	0.98	B4GALT5	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5	8902	0.19
chr1_65631250_65631550	0.97	AK4	adenylate kinase 4	17514	0.23
chr9_71088675_71088967	0.95	RP11-88I18.3		47062	0.14
chr2_167229684_167229835	0.95	SCN9A	sodium channel, voltage-gated, type IX, alpha subunit	2738	0.32
chr1_244373367_244373587	0.95	ENSG00000244066	.	106243	0.07
chr8_70588854_70589419	0.94	ENSG00000222889	.	23323	0.21
chr18_60617582_60618139	0.94	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	47477	0.17
chr8_93865181_93865430	0.94	ENSG00000248858	.	24560	0.18
chr14_25345296_25345447	0.93	STXBP6	syntaxin binding protein 6 (amisyn)	56688	0.15
chr6_18330696_18330847	0.93	ENSG00000200681	.	23461	0.17
chr9_93557450_93557605	0.93	SYK	spleen tyrosine kinase	6542	0.34
chr2_48492787_48493214	0.92	ENSG00000201010	.	48286	0.14
chr2_208130882_208131033	0.92	ENSG00000221628	.	3191	0.28
chr2_200603924_200604101	0.91	FTCDNL1	formiminotransferase cyclodeaminase N-terminal like	111584	0.07
chr12_54655635_54656068	0.90	RP11-968A15.2		548	0.55
chr10_30835364_30835781	0.90	ENSG00000239744	.	9261	0.25
chr2_16806644_16806795	0.90	FAM49A	family with sequence similarity 49, member A	2375	0.44
chr15_69459626_69459923	0.89	ENSG00000266374	.	6784	0.19
chr5_149976523_149976855	0.89	SYNPO	synaptopodin	3953	0.19
chr11_128515950_128516456	0.89	RP11-744N12.3		40120	0.13
chr15_47796944_47797164	0.89	RP11-142J21.2		20312	0.2
chr10_129959144_129959646	0.88	MKI67	marker of proliferation Ki-67	34746	0.23
chr2_152887402_152887696	0.88	CACNB4	calcium channel, voltage-dependent, beta 4 subunit	57064	0.14
chr4_15452943_15453218	0.88	CC2D2A	coiled-coil and C2 domain containing 2A	18409	0.16
chr10_126746005_126746335	0.87	ENSG00000264572	.	24731	0.19
chr2_10538806_10538994	0.87	HPCAL1	hippocalcin-like 1	21247	0.18
chr7_20259929_20260378	0.87	MACC1	metastasis associated in colon cancer 1	3126	0.32
chr9_119708855_119709006	0.86	ENSG00000265662	.	152356	0.04
chr2_135053941_135054092	0.85	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	42186	0.19
chrX_4171213_4171579	0.85	ENSG00000264861	.	330145	0.01
chr14_52701486_52701703	0.85	PTGDR	prostaglandin D2 receptor (DP)	32837	0.2
chr1_160693498_160693649	0.85	CD48	CD48 molecule	11932	0.15
chr12_29318585_29318886	0.85	FAR2	fatty acyl CoA reductase 2	16602	0.24
chr11_72122571_72122823	0.84	RP11-7N14.1		937	0.53
chr5_75661692_75661916	0.84	IQGAP2	IQ motif containing GTPase activating protein 2	37270	0.19
chr3_138581340_138581807	0.84	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	27793	0.2
chr1_109913610_109914092	0.84	SORT1	sortilin 1	22128	0.14
chr6_119770509_119770660	0.83	MAN1A1	mannosidase, alpha, class 1A, member 1	99658	0.08
chr3_45579685_45579844	0.83	LARS2-AS1	LARS2 antisense RNA 1	28727	0.17
chr8_32432657_32432846	0.83	NRG1	neuregulin 1	26506	0.26
chr5_76442660_76442959	0.82	ZBED3-AS1	ZBED3 antisense RNA 1	7735	0.17
chr2_112758544_112758832	0.82	MERTK	c-mer proto-oncogene tyrosine kinase	18302	0.21
chr6_14638853_14639371	0.82	ENSG00000206960	.	7654	0.34
chr10_103608236_103608387	0.82	KCNIP2	Kv channel interacting protein 2	4634	0.19
chr5_77635564_77635798	0.81	SCAMP1	secretory carrier membrane protein 1	20658	0.17
chr15_55615974_55616125	0.80	PIGB	phosphatidylinositol glycan anchor biosynthesis, class B	4606	0.16
chr8_25092329_25092556	0.80	DOCK5	dedicator of cytokinesis 5	50062	0.15
chr2_48689029_48689283	0.79	PPP1R21	protein phosphatase 1, regulatory subunit 21	20888	0.19
chr12_63122687_63123266	0.79	ENSG00000238475	.	78021	0.09
chr8_111685853_111686066	0.79	KCNV1	potassium channel, subfamily V, member 1	697883	0.0
chr6_36280327_36280817	0.79	C6orf222	chromosome 6 open reading frame 222	24090	0.15
chr1_77880967_77881506	0.78	ENSG00000251767	.	4774	0.24
chr10_70809488_70809639	0.78	SRGN	serglycin	38311	0.13
chr7_128789516_128789766	0.78	TSPAN33	tetraspanin 33	4929	0.16
chr12_52085972_52086211	0.78	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit	5884	0.28
chr6_110092021_110092336	0.78	FIG4	FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)	4246	0.32
chr5_153677525_153677842	0.78	ENSG00000221070	.	42003	0.14
chr15_80192571_80192722	0.77	MTHFS	5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)	3255	0.2
chr16_11063472_11063635	0.77	CLEC16A	C-type lectin domain family 16, member A	25115	0.12
chr8_67015841_67015992	0.77	TRIM55	tripartite motif containing 55	23215	0.22
chr12_1727756_1727907	0.77	WNT5B	wingless-type MMTV integration site family, member 5B	1609	0.4
chr12_19398068_19398296	0.77	PLEKHA5	pleckstrin homology domain containing, family A member 5	8324	0.25
chr6_8896917_8897068	0.77	SLC35B3	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3	461198	0.01
chr13_77914205_77914356	0.77	MYCBP2	MYC binding protein 2, E3 ubiquitin protein ligase	13101	0.29
chrX_38757750_38757901	0.77	MID1IP1-AS1	MID1IP1 antisense RNA 1	94689	0.08
chr3_149498560_149498806	0.77	ENSG00000251854	.	1788	0.3
chr3_50272091_50272521	0.77	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	1078	0.35
chr3_119289086_119289376	0.77	ADPRH	ADP-ribosylarginine hydrolase	8884	0.14
chr21_38623577_38623951	0.76	DSCR3	Down syndrome critical region gene 3	15859	0.15
chr1_158624480_158624741	0.76	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	31788	0.12
chr11_34175979_34176130	0.76	ENSG00000201867	.	34667	0.18
chr10_10705396_10705589	0.76	CELF2	CUGBP, Elav-like family member 2	341767	0.01
chrX_1613328_1613643	0.76	ASMTL	acetylserotonin O-methyltransferase-like	40830	0.13
chr20_8223602_8223950	0.76	PLCB1-IT1	PLCB1 intronic transcript 1 (non-protein coding)	5575	0.32
chr8_141115136_141115426	0.76	C8orf17	chromosome 8 open reading frame 17	171865	0.03
chrY_1563328_1563641	0.76	NA	NA	> 10⁶	NA
chr7_111175396_111175590	0.76	IMMP2L	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)	13990	0.31
chr3_113339034_113339327	0.76	ENSG00000241529	.	12371	0.16
chr22_24878693_24878966	0.75	ADORA2A-AS1	ADORA2A antisense RNA 1	11934	0.14
chr10_98476457_98476755	0.75	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	3665	0.26
chr6_6927106_6927418	0.75	ENSG00000240936	.	11868	0.28
chr3_119554508_119554659	0.75	NR1I2	nuclear receptor subfamily 1, group I, member 2	53026	0.14
chr2_145266955_145267602	0.75	ZEB2	zinc finger E-box binding homeobox 2	7837	0.25
chr7_24911589_24911740	0.75	OSBPL3	oxysterol binding protein-like 3	20530	0.22
chr5_171295070_171295446	0.75	SMIM23	small integral membrane protein 23	82368	0.09
chr10_16952291_16952577	0.75	CUBN	cubilin (intrinsic factor-cobalamin receptor)	73760	0.11
chrX_41308314_41308601	0.74	NYX	nyctalopin	1744	0.41
chr3_185533194_185533614	0.73	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2	5445	0.25
chr4_48264920_48265179	0.73	TEC	tec protein tyrosine kinase	6832	0.25
chr1_186799937_186800088	0.73	PLA2G4A	phospholipase A2, group IVA (cytosolic, calcium-dependent)	1890	0.5
chr2_36967324_36967475	0.73	VIT	vitrin	33556	0.19
chr19_4559647_4559798	0.73	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	98	0.94
chr5_67192624_67192790	0.73	ENSG00000223149	.	70566	0.14
chr8_8308239_8308687	0.73	SGK223	Tyrosine-protein kinase SgK223	64455	0.12
chr9_128019719_128019870	0.73	GAPVD1	GTPase activating protein and VPS9 domains 1	4295	0.18
chr7_129665988_129666521	0.73	ENSG00000201109	.	863	0.5
chr2_65080033_65080247	0.73	ENSG00000199964	.	18849	0.16
chr9_124146130_124146281	0.73	RP11-162D16.2		8686	0.17
chr4_48244995_48245289	0.73	TEC	tec protein tyrosine kinase	26739	0.2
chr14_33913404_33913555	0.73	NPAS3	neuronal PAS domain protein 3	228961	0.02
chr1_35297831_35297982	0.72	RP5-997D16.2		18389	0.12
chr2_149836524_149836756	0.72	KIF5C	kinesin family member 5C	32183	0.21
chr18_10213675_10214158	0.72	ENSG00000239031	.	176081	0.03
chr6_139845854_139846090	0.72	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	150215	0.04
chr2_145532540_145532691	0.72	ZEB2	zinc finger E-box binding homeobox 2	253994	0.02
chr2_158866139_158866424	0.72	UPP2	uridine phosphorylase 2	14570	0.21
chr2_122576146_122576503	0.72	TSN	translin	62577	0.13
chr1_72258095_72258279	0.72	NEGR1-IT1	NEGR1 intronic transcript 1 (non-protein coding)	44508	0.21
chr2_145420747_145420991	0.71	ZEB2	zinc finger E-box binding homeobox 2	142248	0.05
chr1_26586170_26586321	0.71	CEP85	centrosomal protein 85kDa	2081	0.21
chr1_54561699_54561850	0.71	AL161915.1	Uncharacterized protein	8194	0.15
chr17_69446095_69446391	0.71	ENSG00000222563	.	138934	0.05
chr18_74290488_74290639	0.71	LINC00908	long intergenic non-protein coding RNA 908	49689	0.14
chr12_116752246_116752536	0.71	MED13L	mediator complex subunit 13-like	37248	0.18
chr7_37024417_37024850	0.70	ELMO1	engulfment and cell motility 1	32	0.98
chr12_116878601_116878852	0.70	ENSG00000264037	.	12603	0.28
chr7_115611710_115611956	0.70	TFEC	transcription factor EC	3529	0.37
chr1_183591259_183591410	0.70	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	13483	0.16
chr11_29130415_29130566	0.70	ENSG00000211499	.	167746	0.04
chr1_246345460_246345709	0.70	ENSG00000202184	.	6836	0.23
chr11_9182138_9182467	0.69	DENND5A	DENN/MADD domain containing 5A	8348	0.2
chr4_6635312_6635463	0.69	MRFAP1	Morf4 family associated protein 1	6431	0.19
chr13_28980953_28981250	0.69	FLT1	fms-related tyrosine kinase 1	60675	0.14
chr4_26794386_26794537	0.69	STIM2	stromal interaction molecule 2	64839	0.12
chr4_184841857_184842008	0.69	STOX2	storkhead box 2	15423	0.25
chr11_44551561_44551712	0.69	CD82	CD82 molecule	34341	0.19
chr2_171807097_171807248	0.69	GORASP2	golgi reassembly stacking protein 2, 55kDa	21341	0.2
chr2_15260083_15260395	0.69	NBAS	neuroblastoma amplified sequence	70282	0.14
chr1_204468090_204468417	0.68	PIK3C2B	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	4401	0.21
chr6_21837529_21837680	0.68	SOX4	SRY (sex determining region Y)-box 4	243533	0.02
chr14_75662934_75663411	0.68	ENSG00000252013	.	5700	0.17
chr5_179219772_179219923	0.68	LTC4S	leukotriene C4 synthase	1140	0.33
chr8_136650233_136650384	0.68	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	95362	0.09
chr10_95375617_95375844	0.68	PDE6C	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	3385	0.2
chr15_50433282_50433433	0.68	ATP8B4	ATPase, class I, type 8B, member 4	21938	0.18
chr21_27692727_27692939	0.68	AP001596.6		58038	0.13
chr1_239999296_239999532	0.68	CHRM3-AS1	CHRM3 antisense RNA 1	63758	0.13
chr15_65632342_65632493	0.68	IGDCC3	immunoglobulin superfamily, DCC subclass, member 3	15832	0.14
chr8_86860992_86861143	0.68	REXO1L10P	REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 10, pseudogene	102322	0.07
chr20_46097093_46097293	0.68	ENSG00000202186	.	15932	0.16
chr11_64755523_64756050	0.67	BATF2	basic leucine zipper transcription factor, ATF-like 2	1959	0.17
chr16_46689835_46690025	0.67	RP11-93O14.2		5573	0.18
chr2_152944696_152944847	0.67	AC079790.2		10071	0.23
chr19_56645363_56645783	0.67	ZNF444	zinc finger protein 444	1605	0.26
chr3_112291281_112291559	0.67	ATG3	autophagy related 3	10527	0.19
chr1_161091020_161091397	0.67	NIT1	nitrilase 1	3300	0.09
chr6_46991314_46991585	0.67	GPR110	G protein-coupled receptor 110	5214	0.29
chr2_217294110_217294294	0.67	SMARCAL1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1	703	0.64
chr11_10277086_10277317	0.67	SBF2	SET binding factor 2	38553	0.14
chr8_74582645_74582852	0.67	STAU2	staufen double-stranded RNA binding protein 2	67814	0.13
chr5_173213667_173213887	0.67	ENSG00000263401	.	56696	0.14
chr9_120406523_120406674	0.67	TLR4	toll-like receptor 4	60012	0.13
chr9_113610120_113610271	0.67	ENSG00000206923	.	55422	0.14
chr8_67697845_67698221	0.67	SGK3	serum/glucocorticoid regulated kinase family, member 3	7816	0.23
chr2_120405265_120405416	0.67	PCDP1	Primary ciliary dyskinesia protein 1	9402	0.22
chr6_161620974_161621165	0.66	AGPAT4	1-acylglycerol-3-phosphate O-acyltransferase 4	50748	0.18
chr17_29701155_29701367	0.66	NF1	neurofibromin 1	15695	0.14
chr17_47447979_47448413	0.66	RP11-81K2.1	Uncharacterized protein	94	0.95
chr10_122509724_122510006	0.66	WDR11-AS1	WDR11 antisense RNA 1	26531	0.24
chr4_71845425_71845576	0.66	DCK	deoxycytidine kinase	12755	0.24
chr14_92927135_92927369	0.66	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	21544	0.23
chr9_130705821_130706050	0.66	RP11-203J24.8		3920	0.11
chr18_70223089_70223259	0.66	CBLN2	cerebellin 2 precursor	11400	0.31
chr15_45016174_45016712	0.65	TRIM69	tripartite motif containing 69	4743	0.17
chr2_16844763_16844970	0.65	FAM49A	family with sequence similarity 49, member A	2230	0.47

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.2	0.8	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.2	0.2	GO:0031392	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2	0.6	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1	0.6	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	1.4	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1	0.5	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.5	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.5	GO:0018101	protein citrullination(GO:0018101)
0.1	0.3	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.3	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1	0.2	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.1	0.2	GO:0060437	lung growth(GO:0060437)
0.1	0.3	GO:0071436	sodium ion export(GO:0071436)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1	0.3	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.3	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1	0.3	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.1	0.2	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1	0.3	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.3	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.4	GO:2000831	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.1	0.3	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.3	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.1	0.3	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.2	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.3	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.1	0.4	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.3	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.3	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.3	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.4	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1	0.5	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.1	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.1	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.1	0.3	GO:0042574	retinal metabolic process(GO:0042574)
0.1	0.3	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.2	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.2	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	0.2	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.1	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1	0.2	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.4	GO:0008228	opsonization(GO:0008228)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.4	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1	0.5	GO:0031017	exocrine pancreas development(GO:0031017)
0.1	0.2	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.2	GO:0009215	purine deoxyribonucleotide metabolic process(GO:0009151) purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.1	0.1	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	0.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.2	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1	0.1	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1	0.2	GO:0010662	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.3	GO:0042832	defense response to protozoan(GO:0042832)
0.1	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.6	GO:0034405	response to fluid shear stress(GO:0034405)
0.1	0.2	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1	0.1	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1	0.4	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.1	0.2	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.2	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.1	0.1	GO:0002125	maternal aggressive behavior(GO:0002125)
0.1	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.1	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.2	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.3	GO:0051775	response to redox state(GO:0051775)
0.1	0.1	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1	0.3	GO:0006572	tyrosine catabolic process(GO:0006572)
0.1	0.4	GO:0042119	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.1	0.2	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.1	0.2	GO:0032328	alanine transport(GO:0032328)
0.1	0.3	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	0.2	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.1	0.2	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.3	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.0	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.0	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.3	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.4	GO:0015671	oxygen transport(GO:0015671)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.3	GO:0042953	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.2	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.2	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.3	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.2	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.3	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.0	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.8	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.2	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.4	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.1	GO:0060406	positive regulation of penile erection(GO:0060406)
0.0	0.3	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.1	GO:0052572	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0	0.2	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.1	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.6	GO:0044036	cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0043049	otic placode formation(GO:0043049)
0.0	0.2	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.5	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.2	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.2	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0060087	relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.5	GO:0051923	sulfation(GO:0051923)
0.0	0.3	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.2	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.1	GO:0060413	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.3	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.9	GO:0021766	hippocampus development(GO:0021766)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.0	GO:0032966	negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0	0.0	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.1	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.3	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.1	GO:2000095	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.2	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.3	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.8	GO:0030318	melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.2	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.2	GO:0050901	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0051769	nitric-oxide synthase biosynthetic process(GO:0051767) regulation of nitric-oxide synthase biosynthetic process(GO:0051769)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.3	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.1	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.0	GO:0021910	smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0	0.3	GO:0046459	short-chain fatty acid metabolic process(GO:0046459)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.3	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.0	GO:0070391	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0042747	circadian sleep/wake cycle, REM sleep(GO:0042747)
0.0	0.1	GO:0051531	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.6	GO:0051693	actin filament capping(GO:0051693)
0.0	0.2	GO:0043496	regulation of protein homodimerization activity(GO:0043496)
0.0	0.0	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.6	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0072179	nephric duct formation(GO:0072179)
0.0	0.6	GO:0097581	lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0045136	development of secondary sexual characteristics(GO:0045136)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0009128	nucleoside monophosphate catabolic process(GO:0009125) purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.6	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.2	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.2	GO:0009650	UV protection(GO:0009650)
0.0	0.1	GO:0001967	suckling behavior(GO:0001967)
0.0	0.2	GO:0061462	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.2	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.4	GO:0042462	photoreceptor cell development(GO:0042461) eye photoreceptor cell development(GO:0042462)
0.0	0.1	GO:0002092	positive regulation of receptor internalization(GO:0002092)
0.0	0.2	GO:0030238	male sex determination(GO:0030238)
0.0	0.1	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.7	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	1.0	GO:0019722	calcium-mediated signaling(GO:0019722)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0001975	response to amphetamine(GO:0001975)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.4	GO:0051324	prophase(GO:0051324)
0.0	0.1	GO:0016265	obsolete death(GO:0016265)
0.0	0.1	GO:0015669	gas transport(GO:0015669)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0048713	regulation of oligodendrocyte differentiation(GO:0048713)
0.0	0.1	GO:0033505	floor plate morphogenesis(GO:0033505)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0032431	positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)
0.0	0.0	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.0	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.3	GO:0008272	sulfate transport(GO:0008272)
0.0	0.1	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.0	0.0	GO:0042640	anagen(GO:0042640)
0.0	0.1	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.0	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.1	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.4	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.3	GO:0046135	pyrimidine nucleoside catabolic process(GO:0046135)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.2	GO:0045132	meiotic chromosome segregation(GO:0045132)
0.0	0.1	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.2	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.0	GO:1901722	regulation of cell proliferation involved in kidney development(GO:1901722)
0.0	0.1	GO:2000573	positive regulation of telomerase activity(GO:0051973) positive regulation of DNA biosynthetic process(GO:2000573)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.0	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.0	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.2	GO:0006206	pyrimidine nucleobase metabolic process(GO:0006206)
0.0	0.1	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.0	GO:0032785	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.0	GO:0042095	interferon-gamma biosynthetic process(GO:0042095)
0.0	0.1	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.2	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0032210	regulation of telomere maintenance via telomerase(GO:0032210) negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0	0.3	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.1	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.0	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.2	GO:0006026	aminoglycan catabolic process(GO:0006026)
0.0	0.1	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0045123	cellular extravasation(GO:0045123)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.1	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0048260	positive regulation of receptor-mediated endocytosis(GO:0048260)
0.0	0.0	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.0	0.1	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.1	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.0	GO:0001866	NK T cell proliferation(GO:0001866) NK T cell activation(GO:0051132)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:0070339	response to bacterial lipoprotein(GO:0032493) detection of bacterial lipoprotein(GO:0042494) response to bacterial lipopeptide(GO:0070339) detection of bacterial lipopeptide(GO:0070340) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0	0.0	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.2	GO:0050830	defense response to Gram-positive bacterium(GO:0050830)
0.0	0.0	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0046471	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0032026	response to magnesium ion(GO:0032026)
0.0	0.0	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.0	GO:0051883	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.0	GO:0050691	regulation of defense response to virus by host(GO:0050691)
0.0	0.2	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.3	GO:0001935	endothelial cell proliferation(GO:0001935)
0.0	0.0	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0	0.1	GO:0042116	macrophage activation(GO:0042116)
0.0	0.0	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.4	GO:0006958	complement activation, classical pathway(GO:0006958)
0.0	0.0	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.2	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.0	GO:0032109	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.2	GO:0007379	segment specification(GO:0007379)
0.0	0.0	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.0	0.0	GO:0033622	integrin activation(GO:0033622)
0.0	0.0	GO:0071624	positive regulation of granulocyte chemotaxis(GO:0071624)
0.0	0.0	GO:0072538	T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0	0.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.3	GO:0033559	unsaturated fatty acid metabolic process(GO:0033559)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0051963	regulation of synapse assembly(GO:0051963)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.0	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.0	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.0	GO:0051154	negative regulation of striated muscle cell differentiation(GO:0051154)
0.0	0.0	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0051567	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.3	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.0	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.0	GO:0072044	collecting duct development(GO:0072044)
0.0	0.3	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	1.1	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.0	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.3	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.0	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.0	GO:0035929	steroid hormone secretion(GO:0035929)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.0	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.1	GO:1900006	positive regulation of dendrite morphogenesis(GO:0050775) positive regulation of dendrite development(GO:1900006)
0.0	0.0	GO:0010954	positive regulation of protein processing(GO:0010954) positive regulation of protein maturation(GO:1903319)
0.0	0.1	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.2	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.0	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.0	GO:0090022	regulation of neutrophil chemotaxis(GO:0090022) regulation of neutrophil migration(GO:1902622)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.0	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.0	GO:0006560	proline metabolic process(GO:0006560) proline biosynthetic process(GO:0006561)
0.0	0.0	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.0	GO:0045921	positive regulation of exocytosis(GO:0045921)
0.0	0.1	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.0	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.0	GO:0048703	embryonic viscerocranium morphogenesis(GO:0048703)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.0	GO:0009084	glutamine family amino acid biosynthetic process(GO:0009084)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.0	GO:0090075	relaxation of muscle(GO:0090075)
0.0	0.0	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0060004	reflex(GO:0060004)
0.0	0.1	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.0	GO:0015816	glycine transport(GO:0015816)
0.0	0.0	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0030904	retromer complex(GO:0030904)
0.1	0.4	GO:0042629	mast cell granule(GO:0042629)
0.1	0.4	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.2	GO:0031904	endosome lumen(GO:0031904)
0.1	0.6	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.2	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	0.5	GO:0000145	exocyst(GO:0000145)
0.1	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0016600	flotillin complex(GO:0016600)
0.0	0.4	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.4	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.2	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.3	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.3	GO:0042588	zymogen granule(GO:0042588)
0.0	0.2	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.3	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.3	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.8	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.8	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.5	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.5	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.4	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.3	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.3	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.4	GO:0043195	terminal bouton(GO:0043195)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.0	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.0	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.2	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.2	GO:0060170	ciliary membrane(GO:0060170)
0.0	0.2	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.8	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	1.0	GO:0030027	lamellipodium(GO:0030027)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.1	GO:0030914	STAGA complex(GO:0030914)
0.0	0.2	GO:0044447	axoneme part(GO:0044447)
0.0	0.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.0	GO:0000791	euchromatin(GO:0000791)
0.0	0.3	GO:0005795	Golgi stack(GO:0005795)
0.0	1.2	GO:0005769	early endosome(GO:0005769)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.2	0.5	GO:0050693	LBD domain binding(GO:0050693)
0.2	0.5	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.4	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.4	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.1	0.4	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.5	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.4	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.5	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.1	0.4	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.6	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	0.4	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	0.3	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.4	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.4	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.1	0.3	GO:0070052	collagen V binding(GO:0070052)
0.1	0.6	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.3	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	0.7	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	0.3	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.2	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	0.2	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.1	GO:0043559	insulin binding(GO:0043559)
0.1	0.6	GO:0019864	IgG binding(GO:0019864)
0.1	0.4	GO:0019956	chemokine binding(GO:0019956)
0.1	0.8	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.6	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1	0.2	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	0.3	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	0.2	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.4	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.1	0.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.1	0.2	GO:0033265	choline binding(GO:0033265)
0.1	0.4	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.3	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.8	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.3	GO:0004568	chitinase activity(GO:0004568)
0.0	0.5	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.2	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.4	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.4	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.3	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.7	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.5	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	1.1	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.5	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.3	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.2	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.3	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.2	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.3	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.0	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.2	GO:0001846	opsonin binding(GO:0001846)
0.0	0.4	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.5	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.3	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.4	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	1.3	GO:0008009	chemokine activity(GO:0008009)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.3	GO:0034739	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.2	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.2	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.6	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.0	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.3	GO:0051119	sugar transmembrane transporter activity(GO:0051119)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.0	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.8	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.3	GO:0030552	cAMP binding(GO:0030552)
0.0	0.0	GO:0004396	hexokinase activity(GO:0004396)
0.0	1.0	GO:0019208	phosphatase regulator activity(GO:0019208)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.0	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0	0.3	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.3	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.6	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0015645	fatty acid ligase activity(GO:0015645)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0080031	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.3	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.1	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.2	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.3	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.0	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	1.2	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.4	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0008519	ammonium transmembrane transporter activity(GO:0008519)
0.0	2.9	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.3	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.1	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.0	GO:0004954	prostanoid receptor activity(GO:0004954)
0.0	0.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.0	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.0	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.3	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.0	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.0	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.0	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.4	GO:0008146	sulfotransferase activity(GO:0008146)
0.0	0.0	GO:0001848	complement binding(GO:0001848)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0015278	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.6	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.4	GO:0016835	carbon-oxygen lyase activity(GO:0016835)
0.0	0.0	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.7	GO:0031267	small GTPase binding(GO:0031267)
0.0	0.0	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.3	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.1	0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	2.8	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.7	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.3	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.3	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	4.3	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.7	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.5	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.3	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.7	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	1.0	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.1	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.3	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.4	PID ATR PATHWAY	ATR signaling pathway
0.0	0.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.4	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.0	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.4	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.3	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	0.7	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.6	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	0.3	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.0	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.1	0.5	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.2	REACTOME HEMOSTASIS	Genes involved in Hemostasis
0.0	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.6	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.9	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.6	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.5	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	1.7	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.1	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.8	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.1	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME DIGESTION OF DIETARY CARBOHYDRATE	Genes involved in Digestion of dietary carbohydrate
0.0	0.3	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.1	REACTOME PLATELET HOMEOSTASIS	Genes involved in Platelet homeostasis
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.2	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.5	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.5	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.4	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.3	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME S PHASE	Genes involved in S Phase
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.4	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.0	REACTOME CELL CELL COMMUNICATION	Genes involved in Cell-Cell communication
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	1.4	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.0	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex

Results for SPIB

Z-value: 4.55

Motif logo

Transcription factors associated with SPIB

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the SPIB motif across conditions

Conditions sorted by the z-value of the SPIB motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIB

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: