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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for STAT1_STAT3_BCL6

Z-value: 3.70

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Transcription factors associated with STAT1_STAT3_BCL6

Gene Symbol	Gene ID	Gene Info
STAT1 Ensembl NCBI GeneCards UniProt	ENSG00000115415.14	signal transducer and activator of transcription 1
STAT3 Ensembl NCBI GeneCards UniProt	ENSG00000168610.10	signal transducer and activator of transcription 3
BCL6 Ensembl NCBI GeneCards UniProt	ENSG00000113916.13	BCL6 transcription repressor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr3_187515842_187515993	BCL6	52402	0.150166	-0.92	4.7e-04	Click!
chr3_187596980_187597131	BCL6	133540	0.049696	0.92	4.9e-04	Click!
chr3_187539986_187540311	BCL6	76633	0.105613	-0.89	1.3e-03	Click!
chr3_187469601_187469752	BCL6	6161	0.241762	-0.88	1.8e-03	Click!
chr3_187469157_187469308	BCL6	5717	0.244640	-0.88	1.9e-03	Click!
chr2_191871931_191872082	STAT1	6307	0.184712	-0.88	1.5e-03	Click!
chr2_191872673_191872906	STAT1	5524	0.189236	-0.84	4.7e-03	Click!
chr2_191873464_191873773	STAT1	4695	0.196482	-0.83	5.1e-03	Click!
chr2_191880278_191880459	STAT1	1392	0.360548	-0.80	9.9e-03	Click!
chr2_191873117_191873421	STAT1	5044	0.193021	-0.78	1.3e-02	Click!
chr17_40541111_40541280	STAT3	609	0.619299	0.88	1.7e-03	Click!
chr17_40509146_40509297	STAT3	31211	0.096921	-0.87	2.0e-03	Click!
chr17_40515206_40515373	STAT3	25143	0.105617	-0.82	6.8e-03	Click!
chr17_40538506_40538657	STAT3	1851	0.234549	-0.77	1.4e-02	Click!
chr17_40499436_40499587	STAT3	40921	0.081986	0.74	2.3e-02	Click!

Activity of the STAT1_STAT3_BCL6 motif across conditions

Conditions sorted by the z-value of the STAT1_STAT3_BCL6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_32155176_32155569	2.78	COL16A1	collagen, type XVI, alpha 1	6023	0.15
chr13_42269724_42270084	2.39	ENSG00000241406	.	111909	0.06
chr12_110388287_110388838	2.29	GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	45467	0.11
chr12_80620548_80620699	2.22	OTOGL	otogelin-like	17390	0.26
chr22_32226444_32226595	2.17	ENSG00000252909	.	6705	0.19
chr1_222545476_222545627	2.11	ENSG00000222399	.	131526	0.05
chr20_19717946_19718153	2.00	ENSG00000239120	.	2496	0.31
chr18_21441508_21442003	2.00	LAMA3	laminin, alpha 3	11049	0.22
chr10_112206935_112207266	1.99	ENSG00000221359	.	13101	0.19
chr14_101308246_101309004	1.96	ENSG00000214548	.	7020	0.04
chr9_124319965_124320687	1.95	DAB2IP	DAB2 interacting protein	9010	0.18
chr1_85098833_85099018	1.91	C1orf180	chromosome 1 open reading frame 180	1494	0.45
chr18_10058054_10058395	1.91	ENSG00000263630	.	53030	0.15
chr6_17930036_17930431	1.88	KIF13A	kinesin family member 13A	57461	0.15
chr15_59642926_59643113	1.85	RP11-356M20.3		9069	0.13
chr7_41045358_41045650	1.82	AC005160.3		230347	0.02
chr4_57946942_57947313	1.82	ENSG00000238541	.	25384	0.14
chr20_4451519_4451670	1.81	PRNP	prion protein	215288	0.02
chr9_117440135_117440286	1.78	ENSG00000272241	.	61383	0.1
chr8_101918990_101919256	1.78	RP11-521I2.3		7493	0.19
chr10_117697374_117697525	1.78	GFRA1	GDNF family receptor alpha 1	317858	0.01
chr14_102429094_102429375	1.77	DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	1631	0.41
chr6_166972111_166972262	1.76	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	14008	0.19
chr1_15734023_15734174	1.76	EFHD2	EF-hand domain family, member D2	2293	0.24
chr3_171873318_171873469	1.74	FNDC3B	fibronectin type III domain containing 3B	28629	0.22
chr13_33836981_33837132	1.71	ENSG00000236581	.	8460	0.23
chr8_22606463_22606685	1.71	ENSG00000253125	.	1558	0.38
chr1_214689137_214689772	1.70	PTPN14	protein tyrosine phosphatase, non-receptor type 14	35112	0.22
chr2_235866357_235866729	1.70	SH3BP4	SH3-domain binding protein 4	5823	0.35
chr8_42052077_42052228	1.70	PLAT	plasminogen activator, tissue	907	0.54
chr7_22691466_22691617	1.67	AC002480.5		9870	0.18
chr10_112158236_112158389	1.67	ENSG00000221359	.	35687	0.17
chr1_101666399_101666550	1.65	ENSG00000238296	.	27847	0.14
chr20_30198397_30198778	1.63	ENSG00000264395	.	3598	0.15
chr11_111606690_111607000	1.62	PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	18917	0.17
chr22_47330400_47330827	1.62	ENSG00000221672	.	86810	0.1
chr1_234669507_234669783	1.62	TARBP1	TAR (HIV-1) RNA binding protein 1	54796	0.11
chr16_4434086_4434404	1.58	VASN	vasorin	12396	0.12
chr17_32581770_32582247	1.57	CCL2	chemokine (C-C motif) ligand 2	296	0.47
chr2_43269199_43269510	1.56	ENSG00000207087	.	49278	0.18
chr8_18704567_18704932	1.56	PSD3	pleckstrin and Sec7 domain containing 3	7135	0.26
chr1_59608109_59608260	1.55	FGGY	FGGY carbohydrate kinase domain containing	154126	0.04
chr3_170806905_170807056	1.54	ENSG00000207963	.	17568	0.23
chr1_246302671_246302822	1.53	RP11-36N20.1		30818	0.18
chr2_101403130_101403281	1.52	NPAS2	neuronal PAS domain protein 2	33409	0.18
chr20_10635653_10635804	1.50	JAG1	jagged 1	7426	0.25
chr1_6579844_6579995	1.49	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	150	0.93
chr1_94547184_94547390	1.47	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	39394	0.15
chr12_25341938_25342089	1.47	CASC1	cancer susceptibility candidate 1	6019	0.18
chr16_58154872_58155238	1.47	CTB-134F13.1		4266	0.14
chr21_40561834_40561985	1.46	AF129408.17		5514	0.18
chr14_59331589_59331740	1.46	ENSG00000221427	.	93700	0.09
chr2_121583155_121583306	1.45	GLI2	GLI family zinc finger 2	28309	0.25
chr2_172203883_172204252	1.45	METTL8	methyltransferase like 8	8301	0.28
chr3_194651773_194651967	1.45	XXYLT1-AS1	XXYLT1 antisense RNA 1	163447	0.03
chr3_187673444_187673880	1.45	LPP	LIM domain containing preferred translocation partner in lipoma	197410	0.03
chr14_72131700_72131851	1.44	SIPA1L1	signal-induced proliferation-associated 1 like 1	46302	0.2
chrX_132742328_132742547	1.43	ENSG00000206765	.	76583	0.11
chr1_117689156_117689307	1.43	TRIM45	tripartite motif containing 45	24022	0.16
chr2_85971566_85971717	1.42	ATOH8	atonal homolog 8 (Drosophila)	9376	0.15
chr3_138212848_138212999	1.41	CEP70	centrosomal protein 70kDa	6099	0.27
chr5_133897463_133897614	1.39	JADE2	jade family PHD finger 2	35211	0.12
chr3_177651904_177652275	1.39	ENSG00000199858	.	73478	0.13
chr14_103584586_103584952	1.39	TNFAIP2	tumor necrosis factor, alpha-induced protein 2	5029	0.18
chr14_75867050_75867708	1.38	RP11-293M10.6		27014	0.16
chr1_230228004_230228155	1.37	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	25061	0.22
chr2_235603383_235603534	1.37	ARL4C	ADP-ribosylation factor-like 4C	197761	0.03
chr5_163391640_163391998	1.36	ENSG00000251998	.	168648	0.04
chr9_112749749_112749900	1.36	AKAP2	A kinase (PRKA) anchor protein 2	61054	0.14
chr2_36659694_36659845	1.36	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	76155	0.1
chr17_42215028_42215179	1.36	ENSG00000212446	.	1746	0.18
chr12_9500081_9500322	1.35	ENSG00000212440	.	60783	0.1
chr1_212091210_212091361	1.35	RP11-552D8.1		86595	0.07
chr3_99824311_99824462	1.35	FILIP1L	filamin A interacting protein 1-like	8971	0.2
chr3_149291004_149291431	1.34	WWTR1	WW domain containing transcription regulator 1	2822	0.29
chr17_55946458_55946802	1.34	CUEDC1	CUE domain containing 1	1854	0.32
chr5_52005333_52005946	1.33	ITGA1	integrin, alpha 1	78091	0.1
chr9_123239594_123239792	1.33	CDK5RAP2	CDK5 regulatory subunit associated protein 2	61	0.99
chr11_8854389_8854649	1.33	ST5	suppression of tumorigenicity 5	1033	0.45
chr5_169646376_169646582	1.32	C5orf58	chromosome 5 open reading frame 58	12972	0.23
chr9_71801904_71802181	1.32	TJP2	tight junction protein 2	12832	0.25
chr1_202545648_202545889	1.32	RP11-569A11.1		27628	0.17
chr4_187542812_187542963	1.31	FAT1	FAT atypical cadherin 1	23709	0.21
chr6_129966569_129967050	1.30	ARHGAP18	Rho GTPase activating protein 18	64561	0.13
chr8_141001651_141001976	1.29	C8orf17	chromosome 8 open reading frame 17	58397	0.15
chr8_57788733_57788884	1.29	ENSG00000206975	.	40835	0.21
chr7_129913523_129914117	1.29	CPA2	carboxypeptidase A2 (pancreatic)	7153	0.15
chr1_201459300_201459763	1.29	CSRP1	cysteine and glycine-rich protein 1	6170	0.17
chr3_134053758_134053909	1.29	AMOTL2	angiomotin like 2	36921	0.17
chr8_108117066_108117217	1.28	ENSG00000211995	.	149585	0.05
chr6_135258046_135258296	1.28	RP11-349J5.2		4359	0.24
chr7_107613357_107613666	1.28	ENSG00000238297	.	26916	0.14
chr18_60104933_60105472	1.27	RP11-640A1.3		59839	0.12
chr19_3374038_3374830	1.27	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	7850	0.19
chr1_157972658_157972809	1.27	KIRREL	kin of IRRE like (Drosophila)	9298	0.21
chr4_107506143_107506294	1.27	ENSG00000222333	.	169276	0.04
chr2_161098235_161098386	1.26	ITGB6	integrin, beta 6	41495	0.2
chr4_129438278_129438436	1.26	PGRMC2	progesterone receptor membrane component 2	228373	0.02
chr1_230817465_230817636	1.26	COG2	component of oligomeric golgi complex 2	3174	0.25
chr9_14212321_14212472	1.25	NFIB	nuclear factor I/B	31599	0.24
chr2_73159267_73159418	1.25	EMX1	empty spiracles homeobox 1	8225	0.24
chr7_75194703_75195027	1.25	ENSG00000264312	.	15356	0.15
chr7_113370975_113371126	1.24	PPP1R3A	protein phosphatase 1, regulatory subunit 3A	188070	0.03
chr15_36654037_36654188	1.24	C15orf41	chromosome 15 open reading frame 41	217700	0.02
chr5_52105602_52106304	1.24	CTD-2288O8.1		22093	0.18
chr2_179418090_179418241	1.24	RP11-65L3.2		4554	0.14
chr2_8288765_8288916	1.23	AC011747.7		527056	0.0
chr4_108631467_108631636	1.23	PAPSS1	3'-phosphoadenosine 5'-phosphosulfate synthase 1	10057	0.29
chr4_22387655_22387806	1.23	ENSG00000238383	.	36657	0.21
chr20_59830581_59830732	1.22	CDH4	cadherin 4, type 1, R-cadherin (retinal)	3174	0.41
chr1_230850007_230850201	1.22	AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	61	0.97
chr7_17564423_17564715	1.22	ENSG00000199473	.	151619	0.04
chr6_137562838_137563161	1.22	IFNGR1	interferon gamma receptor 1	22413	0.24
chr22_41050914_41051065	1.21	MKL1	megakaryoblastic leukemia (translocation) 1	18294	0.18
chr10_121529601_121529889	1.21	ENSG00000242818	.	1986	0.36
chr12_47632951_47633218	1.21	PCED1B	PC-esterase domain containing 1B	15756	0.2
chr17_67171698_67171849	1.20	ABCA10	ATP-binding cassette, sub-family A (ABC1), member 10	25569	0.18
chr12_54731214_54731998	1.20	ENSG00000199122	.	606	0.49
chr2_47500188_47500420	1.20	EPCAM	epithelial cell adhesion molecule	71993	0.09
chr4_174240436_174240652	1.19	RP11-798M19.3		10301	0.14
chr5_15620804_15620955	1.19	FBXL7	F-box and leucine-rich repeat protein 7	4788	0.28
chr3_99742929_99743080	1.19	ENSG00000264897	.	59762	0.12
chr14_51802616_51802767	1.19	ENSG00000201820	.	81950	0.08
chr2_47581703_47581854	1.19	ENSG00000222685	.	5138	0.19
chr12_11811968_11812736	1.19	ETV6	ets variant 6	9564	0.27
chr12_1544482_1544633	1.19	ERC1	ELKS/RAB6-interacting/CAST family member 1	27199	0.18
chr1_56982769_56982964	1.18	PPAP2B	phosphatidic acid phosphatase type 2B	62375	0.14
chr1_66287091_66287242	1.18	PDE4B	phosphodiesterase 4B, cAMP-specific	28302	0.22
chr9_130282072_130282415	1.17	ENSG00000200788	.	49089	0.09
chr17_17780236_17780387	1.17	TOM1L2	target of myb1-like 2 (chicken)	4933	0.19
chr4_186629734_186630027	1.17	ENSG00000207497	.	1241	0.48
chr16_70785355_70785594	1.16	VAC14-AS1	VAC14 antisense RNA 1	3527	0.18
chr4_54346332_54346483	1.16	LNX1-AS1	LNX1 antisense RNA 1	16160	0.22
chr4_37695705_37695856	1.16	ENSG00000207075	.	5844	0.23
chr12_27748050_27748201	1.15	PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)	4156	0.27
chr6_17930684_17931117	1.15	KIF13A	kinesin family member 13A	56794	0.15
chr16_87135908_87136059	1.15	RP11-899L11.3		113538	0.06
chr11_96037349_96037500	1.15	ENSG00000266192	.	37178	0.16
chr1_185829964_185830115	1.15	HMCN1	hemicentin 1	126356	0.06
chr16_73128008_73128159	1.14	ZFHX3	zinc finger homeobox 3	34486	0.18
chr4_184492695_184492895	1.14	ENSG00000239116	.	10659	0.19
chr14_71956022_71956173	1.14	SIPA1L1	signal-induced proliferation-associated 1 like 1	39945	0.17
chr5_34496951_34497135	1.12	RAI14	retinoic acid induced 14	159299	0.04
chr20_10641236_10641387	1.12	JAG1	jagged 1	1843	0.42
chr10_82009607_82010081	1.11	AL359195.1	Uncharacterized protein; cDNA FLJ46261 fis, clone TESTI4025062	378	0.87
chr5_142129306_142129714	1.11	ARHGAP26	Rho GTPase activating protein 26	20439	0.22
chr17_13444014_13444165	1.11	ENSG00000221698	.	2874	0.3
chr2_65087353_65087559	1.11	ENSG00000199964	.	26165	0.15
chr16_3996459_3996610	1.11	RP11-462G12.2		228	0.92
chr16_14458549_14458700	1.11	ENSG00000199130	.	55482	0.12
chr15_38334408_38334605	1.10	TMCO5A	transmembrane and coiled-coil domains 5A	107048	0.08
chr1_39626227_39626378	1.10	ENSG00000222378	.	6334	0.19
chr14_61646262_61646413	1.10	PRKCH	protein kinase C, eta	7940	0.26
chr3_194086079_194086230	1.10	LRRC15	leucine rich repeat containing 15	2055	0.3
chr3_136558030_136558274	1.09	RP11-731C17.2		289	0.89
chr19_4372661_4373353	1.09	SH3GL1	SH3-domain GRB2-like 1	7282	0.08
chr15_98510942_98511093	1.09	ARRDC4	arrestin domain containing 4	7089	0.26
chr6_40747399_40747550	1.09	LRFN2	leucine rich repeat and fibronectin type III domain containing 2	192270	0.03
chr9_96921541_96921733	1.09	ENSG00000199165	.	16597	0.15
chr7_98678378_98678634	1.09	AC004893.11		35300	0.17
chr18_9827718_9828105	1.09	ENSG00000242651	.	2713	0.27
chr13_98087725_98087876	1.08	RAP2A	RAP2A, member of RAS oncogene family	1324	0.57
chr5_136477528_136477679	1.08	SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	171624	0.03
chr4_160113251_160113444	1.08	ENSG00000264105	.	63301	0.11
chr2_25704806_25704957	1.08	AC104699.1		60895	0.13
chr19_5046850_5047001	1.07	KDM4B	lysine (K)-specific demethylase 4B	30589	0.18
chr10_13876708_13876931	1.07	FRMD4A	FERM domain containing 4A	24093	0.2
chr22_43241020_43241246	1.07	ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	12112	0.22
chr12_94288637_94288918	1.07	RP11-1060G2.1		48602	0.13
chr14_100478714_100478865	1.07	EVL	Enah/Vasp-like	6930	0.2
chr2_14775111_14775564	1.07	AC011897.1	Uncharacterized protein	122	0.97
chr10_75697569_75697820	1.06	C10orf55	chromosome 10 open reading frame 55	15159	0.14
chr9_140177222_140177513	1.06	TOR4A	torsin family 4, member A	5166	0.09
chr5_148799995_148800340	1.06	ENSG00000208035	.	8314	0.14
chr21_39531826_39531977	1.05	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	2773	0.27
chr17_60643225_60643376	1.05	TLK2	tousled-like kinase 2	13634	0.18
chr8_19060161_19060312	1.05	SH2D4A	SH2 domain containing 4A	110892	0.07
chr22_43393890_43394145	1.05	PACSIN2	protein kinase C and casein kinase substrate in neurons 2	4429	0.24
chr3_42085911_42086330	1.05	TRAK1	trafficking protein, kinesin binding 1	46442	0.16
chr8_37658951_37659207	1.05	GPR124	G protein-coupled receptor 124	4305	0.17
chr10_24753958_24754109	1.04	KIAA1217	KIAA1217	1427	0.49
chr20_8626654_8626805	1.04	ENSG00000222298	.	35842	0.18
chr3_159484716_159484867	1.04	IQCJ-SCHIP1-AS1	IQCJ-SCHIP1 readthrough antisense RNA 1	1452	0.35
chr5_148801935_148802347	1.04	ENSG00000208035	.	6340	0.15
chr17_39109593_39109744	1.04	KRT39	keratin 39	13476	0.08
chr2_208378114_208378265	1.04	CREB1	cAMP responsive element binding protein 1	16272	0.2
chr7_17484323_17484474	1.04	ENSG00000199473	.	71448	0.13
chr2_127934430_127934663	1.04	CYP27C1	cytochrome P450, family 27, subfamily C, polypeptide 1	28797	0.2
chr1_234792506_234792671	1.03	IRF2BP2	interferon regulatory factor 2 binding protein 2	47317	0.14
chr20_45902699_45902850	1.03	ZMYND8	zinc finger, MYND-type containing 8	24870	0.14
chr13_111934602_111934788	1.03	TEX29	testis expressed 29	38320	0.17
chr3_132356433_132356584	1.03	UBA5	ubiquitin-like modifier activating enzyme 5	16782	0.17
chr6_110719966_110720360	1.02	DDO	D-aspartate oxidase	16602	0.18
chr9_110546728_110546925	1.02	AL162389.1	Uncharacterized protein	6407	0.21
chr19_10714026_10714320	1.02	SLC44A2	solute carrier family 44 (choline transporter), member 2	987	0.37
chr12_13278087_13278467	1.02	GSG1	germ cell associated 1	21658	0.19
chr7_16955025_16955176	1.02	AGR3	anterior gradient 3	33489	0.2
chr1_94559548_94560093	1.02	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	26861	0.17
chr15_38693657_38693808	1.02	FAM98B	family with sequence similarity 98, member B	52596	0.15
chr2_38050870_38051285	1.02	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	85466	0.09

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0001543	ovarian follicle rupture(GO:0001543)
0.4	0.8	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.4	1.5	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.3	0.9	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.3	1.5	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.3	0.8	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.9	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.9	GO:0034063	stress granule assembly(GO:0034063)
0.2	0.9	GO:0051014	actin filament severing(GO:0051014)
0.2	2.2	GO:0043277	apoptotic cell clearance(GO:0043277)
0.2	0.8	GO:0090400	stress-induced premature senescence(GO:0090400)
0.2	0.8	GO:0043589	skin morphogenesis(GO:0043589)
0.2	0.6	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.2	0.6	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.2	0.8	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2	0.7	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.2	0.2	GO:0060433	bronchus development(GO:0060433)
0.2	1.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2	0.3	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.2	0.5	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.2	0.7	GO:0060539	diaphragm development(GO:0060539)
0.2	0.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.2	0.5	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.6	GO:0007028	cytoplasm organization(GO:0007028)
0.1	0.6	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1	0.4	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.8	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.4	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	0.8	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.1	0.5	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.4	GO:0000103	sulfate assimilation(GO:0000103)
0.1	0.5	GO:0046113	nucleobase catabolic process(GO:0046113)
0.1	0.3	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.3	GO:0007412	axon target recognition(GO:0007412)
0.1	0.6	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	0.9	GO:0015871	choline transport(GO:0015871)
0.1	0.3	GO:0048368	lateral mesoderm development(GO:0048368)
0.1	0.4	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.1	GO:0060913	cardiac cell fate determination(GO:0060913)
0.1	0.9	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	0.4	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.5	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.1	0.4	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1	0.5	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.1	0.5	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.5	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.6	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	1.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.1	0.8	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.1	0.1	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.1	0.3	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.5	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.2	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	1.2	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.1	0.4	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.2	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.4	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.4	GO:0008354	germ cell migration(GO:0008354)
0.1	0.5	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.1	0.6	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.3	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.8	GO:0015074	DNA integration(GO:0015074)
0.1	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.3	GO:0001821	histamine secretion(GO:0001821)
0.1	0.5	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.5	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.2	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.2	GO:0043173	nucleotide salvage(GO:0043173)
0.1	0.3	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.3	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.1	0.3	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.2	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.3	GO:0060174	limb bud formation(GO:0060174)
0.1	0.3	GO:0031000	response to caffeine(GO:0031000)
0.1	0.2	GO:0016115	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.5	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.7	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.2	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.1	0.4	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.1	0.6	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.9	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.6	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1	0.5	GO:0007567	parturition(GO:0007567)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.1	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.1	GO:0021894	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.1	0.3	GO:0090030	regulation of steroid hormone biosynthetic process(GO:0090030)
0.1	0.3	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.2	GO:0006734	NADH metabolic process(GO:0006734)
0.1	0.1	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.1	0.3	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.1	GO:0032352	positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.1	0.2	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	0.1	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.1	0.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.1	GO:0060872	semicircular canal development(GO:0060872)
0.1	0.3	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1	0.2	GO:0045136	development of secondary sexual characteristics(GO:0045136)
0.1	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.3	GO:0006591	ornithine metabolic process(GO:0006591)
0.1	0.1	GO:0030185	nitric oxide transport(GO:0030185)
0.1	0.1	GO:0060157	urinary bladder development(GO:0060157)
0.1	0.8	GO:0051310	metaphase plate congression(GO:0051310)
0.1	0.1	GO:0032060	bleb assembly(GO:0032060)
0.1	0.2	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1	0.2	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.1	0.2	GO:0071436	sodium ion export(GO:0071436)
0.1	0.1	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1	0.1	GO:0072311	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.1	GO:0006565	L-serine catabolic process(GO:0006565)
0.1	0.2	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.1	GO:0072178	nephric duct morphogenesis(GO:0072178) mesonephric duct morphogenesis(GO:0072180)
0.1	0.3	GO:0070307	lens fiber cell development(GO:0070307)
0.1	0.3	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.1	0.2	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.1	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.1	0.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1	0.6	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.1	GO:0031223	auditory behavior(GO:0031223)
0.1	1.1	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1	0.2	GO:0021591	ventricular system development(GO:0021591)
0.1	0.1	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.1	0.1	GO:0072179	nephric duct formation(GO:0072179)
0.1	0.2	GO:0045630	positive regulation of type 2 immune response(GO:0002830) positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1	0.2	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.2	GO:0021978	telencephalon regionalization(GO:0021978)
0.1	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.2	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.2	GO:0005997	xylulose metabolic process(GO:0005997)
0.1	0.2	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.4	GO:0000052	citrulline metabolic process(GO:0000052)
0.1	0.2	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.1	0.8	GO:0048286	lung alveolus development(GO:0048286)
0.1	0.2	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.1	0.1	GO:0031338	regulation of vesicle fusion(GO:0031338) positive regulation of vesicle fusion(GO:0031340)
0.1	0.2	GO:0046037	GMP metabolic process(GO:0046037)
0.1	0.2	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.1	GO:1903224	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.5	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.0	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0021508	floor plate formation(GO:0021508)
0.0	0.2	GO:0042253	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0	0.1	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.1	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.2	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.8	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.4	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.5	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.2	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.2	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.5	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.2	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.0	GO:0071462	cellular response to water stimulus(GO:0071462)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.3	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.4	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.0	0.2	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.4	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0	0.0	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.6	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.2	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.1	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.3	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.2	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.8	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.3	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.0	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.3	GO:0010092	specification of organ identity(GO:0010092)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.0	GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0	0.2	GO:0001963	synaptic transmission, dopaminergic(GO:0001963)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.2	GO:0009629	response to gravity(GO:0009629)
0.0	0.0	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.2	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0045628	positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628)
0.0	0.2	GO:0008228	opsonization(GO:0008228)
0.0	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.5	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.4	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0046838	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.3	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.1	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0021930	cell proliferation in hindbrain(GO:0021534) cell proliferation in external granule layer(GO:0021924) cerebellar granule cell precursor proliferation(GO:0021930)
0.0	0.3	GO:0045843	negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.0	0.1	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.0	0.3	GO:0001706	endoderm formation(GO:0001706)
0.0	0.4	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.0	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.0	0.1	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.4	GO:0021983	pituitary gland development(GO:0021983)
0.0	0.6	GO:0006662	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.1	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.2	GO:0009071	glycine catabolic process(GO:0006546) serine family amino acid catabolic process(GO:0009071)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.2	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.5	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.4	GO:0008272	sulfate transport(GO:0008272)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.2	GO:0045008	depyrimidination(GO:0045008)
0.0	0.2	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.1	GO:0060008	Sertoli cell differentiation(GO:0060008)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.0	0.0	GO:0061298	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0033504	floor plate development(GO:0033504)
0.0	0.4	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.7	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.1	GO:0070254	mucus secretion(GO:0070254)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.2	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.3	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.0	GO:0032109	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.0	GO:0032610	interleukin-1 alpha production(GO:0032610) interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.2	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0010898	regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.2	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.2	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.2	GO:0033280	response to vitamin D(GO:0033280)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.2	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.4	GO:0016577	histone demethylation(GO:0016577)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.2	GO:0070168	negative regulation of biomineral tissue development(GO:0070168)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0030728	ovulation(GO:0030728)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0002674	negative regulation of acute inflammatory response(GO:0002674)
0.0	0.5	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0060840	artery development(GO:0060840)
0.0	0.2	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.0	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.1	GO:0006188	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.4	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.4	GO:0051693	actin filament capping(GO:0051693)
0.0	0.0	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.2	GO:0033866	coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.0	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.0	GO:0014029	neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.1	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.0	GO:0048635	negative regulation of muscle organ development(GO:0048635)
0.0	0.0	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0001967	suckling behavior(GO:0001967)
0.0	0.3	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0051096	positive regulation of helicase activity(GO:0051096)
0.0	0.0	GO:0060688	regulation of morphogenesis of a branching structure(GO:0060688)
0.0	0.0	GO:0030432	peristalsis(GO:0030432)
0.0	0.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0030325	adrenal gland development(GO:0030325)
0.0	0.1	GO:0009650	UV protection(GO:0009650)
0.0	0.2	GO:0019098	reproductive behavior(GO:0019098)
0.0	0.0	GO:0043084	penile erection(GO:0043084)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.0	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.2	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.0	GO:0002524	hypersensitivity(GO:0002524) regulation of hypersensitivity(GO:0002883)
0.0	0.1	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.0	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.0	0.5	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0	0.0	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.3	GO:0050999	regulation of nitric-oxide synthase activity(GO:0050999)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.1	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.0	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.1	GO:0034694	response to prostaglandin(GO:0034694)
0.0	0.1	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.0	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0	0.0	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.4	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.1	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.1	GO:0009219	pyrimidine deoxyribonucleotide metabolic process(GO:0009219)
0.0	0.3	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.2	GO:0055010	ventricular cardiac muscle tissue development(GO:0003229) ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0	0.1	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.2	GO:0006220	pyrimidine nucleotide metabolic process(GO:0006220)
0.0	0.3	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0044236	multicellular organism metabolic process(GO:0044236)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.8	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.6	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.2	GO:0019359	nicotinamide nucleotide biosynthetic process(GO:0019359)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.0	GO:1904181	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.1	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.0	GO:0032309	icosanoid secretion(GO:0032309)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:0009267	cellular response to starvation(GO:0009267)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.3	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.0	0.0	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.4	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.4	GO:0006953	acute-phase response(GO:0006953)
0.0	0.0	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0	0.1	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.1	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	0.2	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.0	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:0046541	saliva secretion(GO:0046541)
0.0	0.0	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.3	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.0	GO:0046697	decidualization(GO:0046697)
0.0	0.0	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.0	0.0	GO:0070100	regulation of chemokine-mediated signaling pathway(GO:0070099) negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0098876	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	1.1	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0098810	neurotransmitter reuptake(GO:0098810)
0.0	0.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0010225	response to UV-C(GO:0010225)
0.0	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.1	GO:0045911	positive regulation of DNA recombination(GO:0045911)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0043461	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.0	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.1	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.0	0.0	GO:0043620	regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0	0.0	GO:0010596	negative regulation of endothelial cell migration(GO:0010596)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.1	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.0	0.0	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.1	GO:0010510	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.0	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.3	GO:0051271	negative regulation of cellular component movement(GO:0051271)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.0	GO:0032222	regulation of synaptic transmission, cholinergic(GO:0032222)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:1902743	regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0	0.0	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.4	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0007398	ectoderm development(GO:0007398)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.0	GO:0006907	pinocytosis(GO:0006907)
0.0	0.1	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.0	GO:0043536	positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0	0.1	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.0	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0006582	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0	0.0	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.0	GO:0031268	pseudopodium organization(GO:0031268)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.2	0.9	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	0.8	GO:0071437	invadopodium(GO:0071437)
0.1	0.9	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.8	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	1.5	GO:0000242	pericentriolar material(GO:0000242)
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.4	GO:0032059	bleb(GO:0032059)
0.1	0.3	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.8	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	1.2	GO:0030315	T-tubule(GO:0030315)
0.1	0.3	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.4	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.1	0.5	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.1	0.3	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.2	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	0.3	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.6	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	0.2	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.1	0.4	GO:0001527	microfibril(GO:0001527)
0.1	0.7	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.2	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	0.3	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	0.7	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.1	0.2	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	0.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	0.2	GO:0033646	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	0.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.2	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	0.2	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.1	0.4	GO:0005861	troponin complex(GO:0005861)
0.1	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.3	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.5	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.3	GO:0031143	pseudopodium(GO:0031143)
0.0	0.3	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	1.1	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.9	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.4	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.2	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	1.7	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	3.3	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.7	GO:0030018	Z disc(GO:0030018)
0.0	0.3	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.6	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	2.2	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	8.4	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.3	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.6	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.2	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.3	GO:0016235	aggresome(GO:0016235)
0.0	0.2	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.8	GO:0005814	centriole(GO:0005814)
0.0	0.2	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	1.6	GO:0060076	excitatory synapse(GO:0060076)
0.0	0.6	GO:0030286	dynein complex(GO:0030286)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.6	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.8	GO:0005912	adherens junction(GO:0005912)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.3	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.5	GO:0044449	contractile fiber part(GO:0044449)
0.0	1.1	GO:0016459	myosin complex(GO:0016459)
0.0	0.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	1.5	GO:0045095	keratin filament(GO:0045095)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.4	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.8	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.3	GO:0031513	nonmotile primary cilium(GO:0031513)
0.0	0.1	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.3	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.0	GO:0042629	mast cell granule(GO:0042629)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.1	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.0	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.8	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.3	0.8	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.3	0.8	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.3	1.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3	1.3	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.2	0.7	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2	0.9	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	1.4	GO:0050786	RAGE receptor binding(GO:0050786)
0.2	0.8	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.2	0.6	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.2	0.9	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.2	1.0	GO:0017154	semaphorin receptor activity(GO:0017154)
0.2	0.7	GO:0004470	malic enzyme activity(GO:0004470)
0.2	0.7	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.2	1.3	GO:0030332	cyclin binding(GO:0030332)
0.2	0.6	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.2	0.3	GO:0045545	syndecan binding(GO:0045545)
0.2	0.6	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.9	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.7	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	1.3	GO:0005112	Notch binding(GO:0005112)
0.1	1.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.4	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.4	GO:0016972	thiol oxidase activity(GO:0016972)
0.1	0.5	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.9	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	1.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.4	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	0.3	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.7	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.3	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.3	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.3	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.4	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.6	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.2	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1	0.3	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.4	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.1	0.3	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.2	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1	0.3	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.3	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.3	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.3	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1	0.3	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.2	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1	0.2	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.2	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1	0.3	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	0.2	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.2	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	0.9	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.6	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	0.5	GO:0048185	activin binding(GO:0048185)
0.1	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.4	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	1.0	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	0.2	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.2	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.3	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.2	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.1	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.8	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.3	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.3	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.4	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.5	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.5	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.5	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.1	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.6	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	0.2	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.3	GO:0030492	hemoglobin binding(GO:0030492)
0.1	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.2	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.3	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.2	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.1	0.2	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.2	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.1	0.4	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.2	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.3	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	0.5	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.5	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.2	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.6	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.4	GO:0019864	IgG binding(GO:0019864)
0.0	0.3	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.5	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.5	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.6	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.7	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.3	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.6	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.3	GO:0045502	dynein binding(GO:0045502)
0.0	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.2	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.6	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.5	GO:0005372	water transmembrane transporter activity(GO:0005372)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.3	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.3	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.2	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.3	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.5	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.2	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.3	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.0	1.0	GO:0005518	collagen binding(GO:0005518)
0.0	1.3	GO:0016836	hydro-lyase activity(GO:0016836)
0.0	0.2	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.2	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.2	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.2	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.4	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	1.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.4	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.2	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	1.0	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.3	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.9	GO:0042379	chemokine receptor binding(GO:0042379)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.5	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.1	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.3	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.2	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.0	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.3	GO:0022884	macromolecule transmembrane transporter activity(GO:0022884)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0016725	oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0	0.1	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.3	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.0	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	1.2	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.2	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.0	0.0	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.2	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0042979	ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.0	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.0	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0016917	GABA receptor activity(GO:0016917)
0.0	0.1	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	1.0	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.0	GO:0004104	cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.0	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.0	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.0	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.2	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.6	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.0	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID MYC PATHWAY	C-MYC pathway
0.1	0.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	1.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	0.6	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.8	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	1.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	1.7	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	1.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.9	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	0.7	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	1.7	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.1	1.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.8	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	1.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	2.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.5	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.8	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	1.6	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.4	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.7	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.7	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.6	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.6	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	4.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.9	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.4	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	1.3	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.6	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.5	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.2	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.5	PID FGF PATHWAY	FGF signaling pathway
0.0	0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	3.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.2	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.1	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	1.7	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.1	1.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.1	1.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	0.2	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	1.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	0.4	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.1	0.8	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	0.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	0.1	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.1	0.9	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	0.1	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	1.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.1	0.7	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	0.7	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	1.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.8	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	0.6	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	0.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	0.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	0.2	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.1	0.6	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	0.6	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	0.6	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	1.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	3.0	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	0.5	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	0.4	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	1.0	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	1.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.8	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.5	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.9	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	2.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	1.2	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.9	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	2.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.6	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	1.7	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.6	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.5	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.1	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.0	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.3	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.1	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
0.0	0.2	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME CHROMOSOME MAINTENANCE	Genes involved in Chromosome Maintenance
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.2	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.2	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.2	REACTOME SIGNALING BY FGFR MUTANTS	Genes involved in Signaling by FGFR mutants
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.0	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.2	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.8	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport

Results for STAT1_STAT3_BCL6

Z-value: 3.70

Motif logo

Transcription factors associated with STAT1_STAT3_BCL6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the STAT1_STAT3_BCL6 motif across conditions

Conditions sorted by the z-value of the STAT1_STAT3_BCL6 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT1_STAT3_BCL6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: