Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for STAT4

Z-value: 1.20

Motif logo

logo of

Transcription factors associated with STAT4

Gene Symbol Gene ID Gene Info
STAT4
ENSG00000138378.13 signal transducer and activator of transcription 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr2_192013340_192013491STAT422820.3391310.665.3e-02Click!
chr2_192016485_192016636STAT42380.9416950.561.2e-01Click!
chr2_192056884_192057039STAT4406390.156524-0.491.8e-01Click!
chr2_192012454_192012731STAT431050.2869950.481.9e-01Click!
chr2_192037184_192037335STAT4209370.205608-0.452.2e-01Click!

Activity of the STAT4 motif across conditions

Conditions sorted by the z-value of the STAT4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_136013025_136013297 0.45 RALGDS
 ral guanine nucleotide dissociation stimulator
 6657
 0.15
chr14_75038764_75038974 0.41 LTBP2
 latent transforming growth factor beta binding protein 2
 39906
 0.13
chr5_156621341_156621645 0.39 ITK
 IL2-inducible T-cell kinase
 13656
 0.12
chr1_66518298_66518449 0.37 RP11-397C12.1
1972
 0.41
chr7_24940112_24940263 0.35 ENSG00000238976
 .
 244
 0.94
chr1_90097018_90097733 0.34 RP5-1007M22.2
375
 0.77
chr1_112059507_112059886 0.32 ADORA3
 adenosine A3 receptor
 13314
 0.12
chr12_12647697_12647848 0.30 DUSP16
 dual specificity phosphatase 16
 26287
 0.21
chr7_3102888_3103135 0.30 CARD11
 caspase recruitment domain family, member 11
 19432
 0.23
chr4_109015585_109015736 0.29 LEF1
 lymphoid enhancer-binding factor 1
 71797
 0.1
chr7_144516745_144516896 0.29 TPK1
 thiamin pyrophosphokinase 1
 16326
 0.24
chr13_43149418_43149818 0.29 TNFSF11
 tumor necrosis factor (ligand) superfamily, member 11
 1258
 0.64
chr18_35289879_35290030 0.28 ENSG00000266530
 .
 52856
 0.18
chr4_122111518_122111869 0.28 ENSG00000252183
 .
 2365
 0.34
chr5_156953479_156953635 0.28 ADAM19
 ADAM metallopeptidase domain 19
 23727
 0.15
chr6_159228545_159229058 0.28 EZR-AS1
 EZR antisense RNA 1
 10242
 0.17
chr10_115610846_115611146 0.27 DCLRE1A
 DNA cross-link repair 1A
 2863
 0.22
chr1_112192925_112193076 0.27 ENSG00000201028
 .
 159
 0.95
chr6_25036886_25037064 0.26 RP3-425P12.5
5092
 0.19
chr3_31504876_31505139 0.26 ENSG00000238727
 .
 67578
 0.12
chr7_75248927_75249078 0.26 HIP1
 huntingtin interacting protein 1
 7841
 0.2
chr7_21391785_21392069 0.26 ENSG00000195024
 .
 29054
 0.2
chr14_63670641_63670908 0.26 RHOJ
 ras homolog family member J
 352
 0.91
chr15_60863549_60863700 0.26 RORA
 RAR-related orphan receptor A
 21116
 0.19
chr2_28836401_28836726 0.26 PLB1
 phospholipase B1
 11777
 0.21
chr18_22242340_22242491 0.25 HRH4
 histamine receptor H4
 201722
 0.02
chr11_126336020_126336230 0.25 KIRREL3
 kin of IRRE like 3 (Drosophila)
 25672
 0.18
chr14_38540644_38540853 0.24 CTD-2058B24.2
19615
 0.24
chr1_167468557_167468835 0.24 CD247
 CD247 molecule
 19079
 0.18
chr17_37937298_37937847 0.24 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 3094
 0.19
chr3_113250406_113250557 0.24 SIDT1
 SID1 transmembrane family, member 1
 662
 0.69
chr4_143634715_143634901 0.24 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 132635
 0.06
chr2_68948486_68948822 0.24 ARHGAP25
 Rho GTPase activating protein 25
 11020
 0.25
chr20_30392262_30392413 0.24 MYLK2
 myosin light chain kinase 2
 14774
 0.14
chr7_17068483_17068634 0.24 AGR3
 anterior gradient 3
 146947
 0.04
chr2_42352864_42353761 0.24 EML4
 echinoderm microtubule associated protein like 4
 43178
 0.15
chr13_99209848_99210037 0.23 STK24
 serine/threonine kinase 24
 19175
 0.2
chr10_21807546_21807797 0.23 SKIDA1
 SKI/DACH domain containing 1
 823
 0.52
chr3_17341812_17341972 0.23 TBC1D5
 TBC1 domain family, member 5
 106320
 0.08
chr3_196291691_196292106 0.23 WDR53
 WD repeat domain 53
 2283
 0.21
chr15_38976681_38977159 0.23 C15orf53
 chromosome 15 open reading frame 53
 11879
 0.28
chr4_186173181_186173380 0.23 SNX25
 sorting nexin 25
 42047
 0.13
chr21_34302222_34302373 0.23 AP000281.2
80053
 0.07
chr1_206942223_206942745 0.23 IL10
 interleukin 10
 3355
 0.2
chr3_53072289_53072451 0.23 SFMBT1
 Scm-like with four mbt domains 1
 6911
 0.19
chr20_57735088_57735478 0.23 ZNF831
 zinc finger protein 831
 30792
 0.19
chr2_55193973_55194124 0.23 RTN4
 reticulon 4
 43537
 0.15
chr1_197737430_197737581 0.23 DENND1B
 DENN/MADD domain containing 1B
 6817
 0.23
chr15_64454533_64454724 0.23 PPIB
 peptidylprolyl isomerase B (cyclophilin B)
 776
 0.59
chr19_47935849_47936000 0.22 MEIS3
 Meis homeobox 3
 13144
 0.14
chr2_204854148_204854486 0.22 ICOS
 inducible T-cell co-stimulator
 52814
 0.17
chr3_45983815_45984178 0.22 CXCR6
 chemokine (C-X-C motif) receptor 6
 968
 0.5
chr16_67018785_67019348 0.22 CES4A
 carboxylesterase 4A
 3426
 0.14
chr17_71588187_71588481 0.22 RP11-277J6.2
48831
 0.13
chr11_18640352_18640885 0.22 SPTY2D1
 SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
 15422
 0.14
chr3_50609823_50610526 0.21 C3orf18
 chromosome 3 open reading frame 18
 1752
 0.28
chr14_22627506_22627657 0.21 ENSG00000238634
 .
 16694
 0.27
chr16_87495374_87495580 0.21 ZCCHC14
 zinc finger, CCHC domain containing 14
 28737
 0.15
chr14_50437257_50437517 0.21 C14orf182
 chromosome 14 open reading frame 182
 36851
 0.12
chr20_49168238_49168495 0.21 ENSG00000239742
 .
 6169
 0.15
chr9_121284831_121284982 0.21 ENSG00000251847
 .
 791157
 0.0
chr5_75622593_75622811 0.21 RP11-466P24.6
15415
 0.26
chr9_101854958_101855213 0.21 TGFBR1
 transforming growth factor, beta receptor 1
 11235
 0.23
chr10_18069015_18069166 0.21 TMEM236
27863
 0.17
chr8_67452033_67452620 0.21 ENSG00000206949
 .
 38780
 0.13
chr22_36558393_36558682 0.21 APOL3
 apolipoprotein L, 3
 1560
 0.43
chr11_118109252_118109403 0.20 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 13518
 0.13
chr19_11085110_11085263 0.20 SMARCA4
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
 9642
 0.13
chr10_69371869_69372293 0.20 CTNNA3
 catenin (cadherin-associated protein), alpha 3
 35190
 0.23
chr5_131732657_131732808 0.20 C5orf56
 chromosome 5 open reading frame 56
 13596
 0.12
chr6_130505643_130505870 0.20 SAMD3
 sterile alpha motif domain containing 3
 29758
 0.2
chr10_496561_496809 0.20 RP11-490E15.2
13184
 0.2
chr20_33131898_33132049 0.20 MAP1LC3A
 microtubule-associated protein 1 light chain 3 alpha
 2685
 0.23
chr8_2078833_2079052 0.20 MYOM2
 myomesin 2
 85758
 0.1
chr1_26031102_26031259 0.20 MAN1C1
 mannosidase, alpha, class 1C, member 1
 4913
 0.2
chr4_116134565_116134716 0.20 NDST4
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
 99608
 0.09
chr2_225790470_225790675 0.20 DOCK10
 dedicator of cytokinesis 10
 21210
 0.27
chr11_118123821_118123979 0.20 MPZL3
 myelin protein zero-like 3
 835
 0.52
chr7_50431752_50432472 0.19 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 64867
 0.11
chr1_43399996_43400147 0.19 SLC2A1
 solute carrier family 2 (facilitated glucose transporter), member 1
 3275
 0.24
chr8_59569855_59570006 0.19 NSMAF
 neutral sphingomyelinase (N-SMase) activation associated factor
 2163
 0.35
chr2_64978837_64979534 0.19 ENSG00000253082
 .
 24053
 0.19
chr6_118978234_118978481 0.19 CEP85L
 centrosomal protein 85kDa-like
 4674
 0.33
chr5_75586536_75586687 0.19 RP11-466P24.6
20676
 0.26
chr13_74601733_74602123 0.19 KLF12
 Kruppel-like factor 12
 32742
 0.25
chr11_58407663_58407869 0.19 CNTF
 ciliary neurotrophic factor
 17620
 0.14
chr7_72929480_72929631 0.19 BAZ1B
 bromodomain adjacent to zinc finger domain, 1B
 7047
 0.15
chr5_156644620_156644840 0.19 CTB-4E7.1
6660
 0.14
chr3_170995564_170995715 0.19 TNIK
 TRAF2 and NCK interacting kinase
 52139
 0.17
chr6_26174520_26174671 0.19 HIST1H2BE
 histone cluster 1, H2be
 9363
 0.06
chr13_43562200_43562351 0.19 EPSTI1
 epithelial stromal interaction 1 (breast)
 3092
 0.34
chr3_56832571_56832900 0.19 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 3242
 0.36
chr1_228928769_228929191 0.19 RHOU
 ras homolog family member U
 58156
 0.09
chr6_42008817_42009180 0.19 CCND3
 cyclin D3
 7426
 0.16
chr14_91668757_91668960 0.19 C14orf159
 chromosome 14 open reading frame 159
 6121
 0.19
chr12_104912220_104912483 0.19 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 61572
 0.13
chr10_120973836_120973987 0.19 ENSG00000242853
 .
 1542
 0.31
chr22_23190435_23190586 0.19 IGLV3-6
 immunoglobulin lambda variable 3-6 (pseudogene)
 2040
 0.09
chr14_69090040_69090191 0.18 CTD-2325P2.4
5047
 0.29
chr1_160535898_160536088 0.18 CD84
 CD84 molecule
 13270
 0.13
chr15_75159560_75159711 0.18 SCAMP2
 secretory carrier membrane protein 2
 5746
 0.12
chr11_12179023_12179437 0.18 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 3760
 0.32
chr4_76859668_76859847 0.18 NAAA
 N-acylethanolamine acid amidase
 1656
 0.28
chr12_15715155_15715553 0.18 PTPRO
 protein tyrosine phosphatase, receptor type, O
 16068
 0.26
chr11_67212387_67212841 0.18 CORO1B
 coronin, actin binding protein, 1B
 1351
 0.18
chr16_5022975_5023126 0.18 PPL
 periplakin
 12308
 0.14
chr11_47287617_47287768 0.18 MADD
 MAP-kinase activating death domain
 3020
 0.14
chr5_96341021_96341172 0.18 ENSG00000200884
 .
 42635
 0.13
chr17_62965440_62965774 0.18 AMZ2P1
 archaelysin family metallopeptidase 2 pseudogene 1
 4028
 0.17
chr17_55519809_55520223 0.18 ENSG00000263902
 .
 30454
 0.2
chr1_28525263_28525593 0.18 AL353354.2
1642
 0.2
chr14_89632758_89632909 0.18 FOXN3
 forkhead box N3
 14255
 0.28
chr1_39658074_39658238 0.18 MACF1
 microtubule-actin crosslinking factor 1
 11762
 0.17
chr13_25171578_25171729 0.18 ENSG00000211508
 .
 11564
 0.18
chr1_39572189_39572340 0.18 MACF1
 microtubule-actin crosslinking factor 1
 1181
 0.46
chr12_53765461_53765679 0.18 SP1
 Sp1 transcription factor
 8390
 0.12
chr1_100917512_100917831 0.18 RP5-837M10.4
33882
 0.17
chr17_40859652_40859819 0.18 CTD-3193K9.3
8251
 0.09
chr7_44666023_44666225 0.18 OGDH
 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
 2063
 0.32
chr16_68326071_68326222 0.18 ENSG00000252026
 .
 7925
 0.08
chr14_52753608_52753759 0.18 PTGDR
 prostaglandin D2 receptor (DP)
 19153
 0.22
chr8_66913743_66914032 0.18 DNAJC5B
 DnaJ (Hsp40) homolog, subfamily C, member 5 beta
 19908
 0.26
chr7_50302307_50302807 0.18 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 41767
 0.19
chr4_55543624_55543775 0.18 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
 19614
 0.29
chr16_50874827_50875162 0.18 ENSG00000199771
 .
 28492
 0.15
chr17_37914078_37914229 0.18 GRB7
 growth factor receptor-bound protein 7
 15648
 0.11
chr5_70884126_70884318 0.18 MCCC2
 methylcrotonoyl-CoA carboxylase 2 (beta)
 1027
 0.62
chr1_26704569_26704720 0.18 ZNF683
 zinc finger protein 683
 3631
 0.15
chr10_98624657_98624808 0.18 LCOR
 ligand dependent nuclear receptor corepressor
 31995
 0.15
chr14_50507439_50508114 0.17 ENSG00000201358
 .
 27510
 0.13
chr22_40349969_40350170 0.17 RP3-370M22.8
6332
 0.18
chr10_27145692_27145938 0.17 ABI1
 abl-interactor 1
 3977
 0.23
chr3_114051977_114052128 0.17 ENSG00000207770
 .
 16636
 0.16
chr14_99688948_99689139 0.17 AL109767.1
40242
 0.16
chr14_35884998_35885149 0.17 NFKBIA
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
 11121
 0.26
chr14_98677293_98677464 0.17 ENSG00000222066
 .
 120709
 0.06
chr2_231517982_231518133 0.17 CAB39
 calcium binding protein 39
 59503
 0.11
chr5_87436602_87437127 0.17 TMEM161B
 transmembrane protein 161B
 79584
 0.11
chr11_35180171_35180536 0.17 CD44
 CD44 molecule (Indian blood group)
 17765
 0.15
chr3_133210635_133210930 0.17 BFSP2-AS1
 BFSP2 antisense RNA 1
 36162
 0.16
chr2_193045009_193045160 0.17 TMEFF2
 transmembrane protein with EGF-like and two follistatin-like domains 2
 14166
 0.3
chr17_26206098_26206388 0.17 LYRM9
 LYR motif containing 9
 4080
 0.19
chr18_20629843_20630057 0.17 ENSG00000223023
 .
 25391
 0.15
chr1_198509908_198510168 0.17 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
 37
 0.99
chr5_43397749_43397909 0.17 CCL28
 chemokine (C-C motif) ligand 28
 463
 0.84
chr17_16322494_16322752 0.17 TRPV2
 transient receptor potential cation channel, subfamily V, member 2
 28
 0.96
chr8_59974482_59974633 0.17 RP11-25K19.1
57042
 0.12
chr2_218811497_218811648 0.17 TNS1
 tensin 1
 2721
 0.31
chr20_50019481_50019826 0.17 ENSG00000263645
 .
 25795
 0.22
chr12_31231062_31231213 0.17 DDX11
 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
 317
 0.82
chr7_149565914_149566574 0.17 ATP6V0E2
 ATPase, H+ transporting V0 subunit e2
 3813
 0.19
chr1_246984990_246985280 0.17 ENSG00000252011
 .
 11696
 0.16
chr6_37672753_37673067 0.17 MDGA1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 5828
 0.28
chr3_4881435_4881664 0.17 ENSG00000239126
 .
 38837
 0.16
chrX_117644722_117644873 0.17 DOCK11
 dedicator of cytokinesis 11
 14925
 0.24
chr11_32444065_32444216 0.17 WT1
 Wilms tumor 1
 4997
 0.26
chr2_74518143_74518523 0.17 SLC4A5
 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
 501
 0.75
chr3_188041188_188041339 0.17 LPP
 LIM domain containing preferred translocation partner in lipoma
 83611
 0.1
chr12_12116177_12116328 0.17 ETV6
 ets variant 6
 77381
 0.1
chr7_156744058_156744240 0.17 NOM1
 nucleolar protein with MIF4G domain 1
 1732
 0.36
chr13_25200724_25201013 0.17 ENSG00000211508
 .
 17651
 0.18
chr22_40915359_40915510 0.17 RP4-591N18.2
2370
 0.26
chr11_11158749_11159001 0.17 RP11-567I13.1
215098
 0.02
chr1_160605831_160606299 0.17 SLAMF1
 signaling lymphocytic activation molecule family member 1
 10746
 0.16
chr1_203285551_203285702 0.17 ENSG00000202300
 .
 2601
 0.25
chr3_56831512_56831764 0.17 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 4339
 0.33
chr12_47588304_47588625 0.17 ENSG00000263838
 .
 6869
 0.23
chr11_14436549_14436842 0.17 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
 50643
 0.14
chr10_96163536_96163687 0.17 TBC1D12
 TBC1 domain family, member 12
 1350
 0.49
chr20_55204811_55205013 0.17 TFAP2C
 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
 378
 0.84
chr2_198066929_198067080 0.17 ANKRD44
 ankyrin repeat domain 44
 4242
 0.23
chr2_46089761_46089912 0.17 PRKCE
 protein kinase C, epsilon
 138205
 0.05
chr17_66251665_66252057 0.17 ARSG
 arylsulfatase G
 3462
 0.19
chr5_35618942_35619093 0.16 SPEF2
 sperm flagellar 2
 917
 0.65
chr20_23620821_23620972 0.16 CST3
 cystatin C
 1786
 0.34
chr16_9010574_9010725 0.16 USP7
 ubiquitin specific peptidase 7 (herpes virus-associated)
 19064
 0.15
chr15_64916469_64916762 0.16 ENSG00000207223
 .
 28472
 0.13
chrX_99880234_99880385 0.16 TSPAN6
 tetraspanin 6
 11494
 0.18
chr8_105634588_105634739 0.16 RP11-127H5.1
 Uncharacterized protein
 31702
 0.18
chr4_83135377_83135528 0.16 ENSG00000202485
 .
 39752
 0.19
chr15_101135936_101136223 0.16 LINS
 lines homolog (Drosophila)
 1062
 0.44
chr8_97175837_97176070 0.16 GDF6
 growth differentiation factor 6
 2933
 0.31
chr16_56296813_56297090 0.16 ENSG00000265281
 .
 17519
 0.16
chr17_46911451_46911733 0.16 CALCOCO2
 calcium binding and coiled-coil domain 2
 3002
 0.17
chr19_35867894_35868045 0.16 GPR42
 G protein-coupled receptor 42 (gene/pseudogene)
 5777
 0.11
chr20_36322114_36322265 0.16 CTNNBL1
 catenin, beta like 1
 219
 0.96
chr8_8195680_8195853 0.16 SGK223
 Tyrosine-protein kinase SgK223
 43491
 0.16
chr6_1895461_1895612 0.16 GMDS
 GDP-mannose 4,6-dehydratase
 280689
 0.01
chr4_15796755_15796906 0.16 CD38
 CD38 molecule
 16929
 0.23
chr5_55980507_55980731 0.16 AC022431.2
 Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
 78560
 0.09
chr9_101789506_101789792 0.16 TGFBR1
 transforming growth factor, beta receptor 1
 76671
 0.09
chr1_22414609_22414772 0.16 CDC42-IT1
 CDC42 intronic transcript 1 (non-protein coding)
 29000
 0.12
chr10_6087510_6087742 0.16 IL2RA
 interleukin 2 receptor, alpha
 16627
 0.13
chr10_116261811_116262124 0.16 ABLIM1
 actin binding LIM protein 1
 14215
 0.25
chr1_157102658_157102809 0.16 ETV3
 ets variant 3
 5426
 0.24
chr3_68106098_68106274 0.16 FAM19A1
 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
 50813
 0.19
chr1_197745376_197745655 0.16 DENND1B
 DENN/MADD domain containing 1B
 752
 0.71
chr14_76063633_76063784 0.16 ENSG00000201096
 .
 6808
 0.16
chr8_59961070_59961221 0.16 RP11-328K2.1
55648
 0.13
chr9_100689273_100689424 0.16 C9orf156
 chromosome 9 open reading frame 156
 4496
 0.17

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.3 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.2 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.1 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0002669 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0002227 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.1 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0072224 metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0 0.1 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0043379 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 1.1 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.2 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.0 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.0 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.0 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:1903170 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.0 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.0 0.1 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:1903313 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.0 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.0 GO:0070602 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0032971 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0051023 immunoglobulin secretion(GO:0048305) regulation of immunoglobulin secretion(GO:0051023)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.0 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.0 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.0 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.0 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.0 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0090079 translation activator activity(GO:0008494) translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.0 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0035004 phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.0 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events