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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for STAT6

Z-value: 1.68

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Transcription factors associated with STAT6

Gene Symbol	Gene ID	Gene Info
STAT6 Ensembl NCBI GeneCards UniProt	ENSG00000166888.6	STAT6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
STAT6	chr12_57488394_57488545	5108	0.107973	-0.77	1.6e-02	Click!
STAT6	chr12_57526252_57526403	405	0.721269	-0.76	1.8e-02	Click!
STAT6	chr12_57529413_57529564	3566	0.125468	-0.72	2.8e-02	Click!
STAT6	chr12_57500945_57501096	1985	0.184003	0.68	4.6e-02	Click!
STAT6	chr12_57498051_57498202	909	0.399202	0.67	4.6e-02	Click!

Activity of the STAT6 motif across conditions

Conditions sorted by the z-value of the STAT6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr18_67615445_67615629	0.92	CD226	CD226 molecule	448	0.89
chr2_114450472_114450623	0.77	ENSG00000202427	.	11859	0.17
chr15_70012378_70012582	0.75	ENSG00000238870	.	10681	0.27
chr11_117879405_117879639	0.70	IL10RA	interleukin 10 receptor, alpha	22413	0.16
chr15_70853193_70853484	0.67	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	141282	0.05
chr15_50849001_50849220	0.66	RP11-120K9.2		688	0.65
chr12_68025335_68025706	0.66	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	16598	0.25
chr13_41578402_41578595	0.65	ELF1	E74-like factor 1 (ets domain transcription factor)	14952	0.19
chr14_22925588_22925851	0.57	TRDD3	T cell receptor delta diversity 3	7614	0.11
chr1_90160802_90161019	0.54	LRRC8C	leucine rich repeat containing 8 family, member C	62279	0.09
chr14_22520830_22521052	0.53	ENSG00000238634	.	89946	0.09
chr15_75068046_75068312	0.53	CSK	c-src tyrosine kinase	6219	0.12
chr1_70672079_70672260	0.52	SRSF11	serine/arginine-rich splicing factor 11	751	0.44
chr7_139922545_139922896	0.52	ENSG00000199971	.	13249	0.16
chr6_74130116_74130267	0.52	ENSG00000266346	.	12516	0.09
chr11_118177738_118177927	0.52	CD3E	CD3e molecule, epsilon (CD3-TCR complex)	2218	0.21
chr10_94875150_94875317	0.52	CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	41586	0.15
chr12_55350316_55350467	0.51	TESPA1	thymocyte expressed, positive selection associated 1	6090	0.26
chr13_42966290_42966473	0.51	AKAP11	A kinase (PRKA) anchor protein 11	120092	0.06
chr6_112020418_112020739	0.51	FYN	FYN oncogene related to SRC, FGR, YES	20687	0.21
chr2_175446825_175447268	0.50	WIPF1	WAS/WASL interacting protein family, member 1	3271	0.21
chr6_25085634_25085917	0.50	FAM65B	family with sequence similarity 65, member B	43537	0.13
chr8_29964950_29965250	0.50	LEPROTL1	leptin receptor overlapping transcript-like 1	5644	0.16
chr1_114423728_114423887	0.50	BCL2L15	BCL2-like 15	6190	0.12
chr21_47973085_47973420	0.49	ENSG00000272283	.	17543	0.17
chr4_6919752_6920098	0.49	TBC1D14	TBC1 domain family, member 14	7950	0.19
chr11_128163135_128163286	0.49	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	212079	0.02
chr7_115362594_115362788	0.49	ENSG00000199224	.	110736	0.07
chrX_13715085_13715236	0.49	RAB9A	RAB9A, member RAS oncogene family	7916	0.19
chr2_240261426_240261658	0.48	ENSG00000264292	.	11957	0.18
chr15_91863778_91863929	0.48	SV2B	synaptic vesicle glycoprotein 2B	94753	0.08
chr22_29206706_29206928	0.48	CTA-292E10.8		4085	0.17
chr6_159438810_159439148	0.48	RP1-111C20.4		7999	0.19
chr10_11234420_11234733	0.47	RP3-323N1.2		21237	0.2
chr6_135409209_135409398	0.47	HBS1L	HBS1-like (S. cerevisiae)	14891	0.21
chr12_6557124_6557320	0.47	CD27	CD27 molecule	3189	0.12
chr17_78639629_78639885	0.47	RPTOR	regulatory associated protein of MTOR, complex 1	120489	0.05
chrX_78513124_78513404	0.47	GPR174	G protein-coupled receptor 174	86795	0.1
chr22_40492159_40492310	0.46	TNRC6B	trinucleotide repeat containing 6B	50756	0.13
chr1_101706731_101706882	0.46	RP4-575N6.5		1908	0.27
chr1_209928684_209929195	0.46	TRAF3IP3	TRAF3 interacting protein 3	438	0.78
chr1_160635552_160635705	0.46	RP11-404F10.2		4940	0.18
chr5_112047575_112047726	0.46	APC	adenomatous polyposis coli	4431	0.29
chr1_154468239_154468540	0.45	SHE	Src homology 2 domain containing E	6200	0.13
chr11_121356356_121356507	0.45	RP11-730K11.1		32709	0.2
chr3_141212059_141212250	0.45	RASA2	RAS p21 protein activator 2	6263	0.24
chrX_56395231_56395532	0.45	KLF8	Kruppel-like factor 8	135901	0.05
chr10_6633477_6633792	0.45	PRKCQ	protein kinase C, theta	11371	0.31
chr2_198102074_198102225	0.45	ANKRD44	ankyrin repeat domain 44	39387	0.14
chr17_79318286_79318703	0.44	TMEM105	transmembrane protein 105	14020	0.13
chr11_128599507_128599754	0.44	SENCR	smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA	33712	0.15
chr15_86128935_86129221	0.43	RP11-815J21.2		5669	0.19
chr20_32212304_32212518	0.43	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2	14134	0.12
chr15_38958003_38958154	0.43	C15orf53	chromosome 15 open reading frame 53	30721	0.22
chr11_46352086_46352730	0.43	DGKZ	diacylglycerol kinase, zeta	2047	0.27
chr1_109188369_109188646	0.43	HENMT1	HEN1 methyltransferase homolog 1 (Arabidopsis)	15170	0.19
chr21_43657083_43657327	0.43	ENSG00000223262	.	15922	0.16
chr5_54397274_54397694	0.42	GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	992	0.48
chr2_10472354_10472745	0.42	HPCAL1	hippocalcin-like 1	28723	0.15
chr2_46532306_46532656	0.42	EPAS1	endothelial PAS domain protein 1	7940	0.28
chr11_95420864_95421015	0.42	FAM76B	family with sequence similarity 76, member B	99030	0.08
chr3_14924290_14924594	0.42	FGD5	FYVE, RhoGEF and PH domain containing 5	61503	0.1
chr2_54805783_54806138	0.42	SPTBN1	spectrin, beta, non-erythrocytic 1	20429	0.18
chr10_63868726_63869208	0.42	ENSG00000221094	.	7007	0.28
chr19_16493025_16493192	0.42	ENSG00000243745	.	16662	0.13
chr11_68295964_68296242	0.41	PPP6R3	protein phosphatase 6, regulatory subunit 3	6776	0.19
chr1_169640913_169641224	0.41	SELL	selectin L	39771	0.13
chr6_149475117_149475268	0.41	ENSG00000263481	.	22738	0.21
chr16_67548433_67548608	0.41	FAM65A	family with sequence similarity 65, member A	3801	0.11
chr2_102331029_102331308	0.41	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	16176	0.28
chrX_37635148_37635299	0.41	CYBB	cytochrome b-245, beta polypeptide	4041	0.29
chr13_22761746_22761897	0.41	ENSG00000244197	.	397145	0.01
chr1_21619210_21619452	0.41	RP5-1071N3.1		452	0.77
chr17_46189481_46189632	0.41	SNX11	sorting nexin 11	245	0.86
chr5_156697606_156697782	0.41	CYFIP2	cytoplasmic FMR1 interacting protein 2	1332	0.36
chr6_6609605_6609822	0.41	LY86-AS1	LY86 antisense RNA 1	13215	0.24
chr7_106513106_106513257	0.41	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	7257	0.28
chr6_152023478_152023738	0.41	ESR1	estrogen receptor 1	11977	0.26
chr11_128186968_128187150	0.41	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	188230	0.03
chr6_111412837_111412988	0.40	ENSG00000200926	.	377	0.86
chr2_106462117_106462355	0.40	NCK2	NCK adaptor protein 2	5968	0.26
chr17_8804803_8804954	0.40	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	9946	0.22
chr5_169703034_169703822	0.40	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	9097	0.23
chr1_226899852_226900133	0.40	ITPKB	inositol-trisphosphate 3-kinase B	25167	0.18
chr1_93418442_93418689	0.40	FAM69A	family with sequence similarity 69, member A	8492	0.13
chr12_66788011_66788363	0.40	ENSG00000238528	.	48688	0.15
chr11_14460647_14460848	0.40	ENSG00000251991	.	39691	0.16
chr22_38001178_38001891	0.40	GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	2947	0.15
chr13_51185358_51185546	0.40	DLEU7-AS1	DLEU7 antisense RNA 1	196540	0.03
chr8_61706063_61706431	0.40	RP11-33I11.2		15918	0.26
chr10_63818672_63818842	0.39	ARID5B	AT rich interactive domain 5B (MRF1-like)	9787	0.27
chr7_2301462_2301726	0.39	NUDT1	nudix (nucleoside diphosphate linked moiety X)-type motif 1	19054	0.15
chr14_106963793_106964019	0.39	IGHV1-45	immunoglobulin heavy variable 1-45	482	0.45
chr16_66590720_66590967	0.39	CKLF-CMTM1	CKLF-CMTM1 readthrough	4291	0.1
chr11_6770353_6770504	0.39	OR2AG2	olfactory receptor, family 2, subfamily AG, member 2	19858	0.11
chr1_101555514_101555760	0.39	RP11-421L21.3		17421	0.18
chrX_135844985_135845136	0.39	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	4442	0.21
chr10_11224083_11224251	0.39	RP3-323N1.2		10828	0.22
chr3_66553234_66553385	0.38	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1	1874	0.51
chr19_40443292_40443443	0.38	FCGBP	Fc fragment of IgG binding protein	2834	0.23
chr2_198167309_198167571	0.38	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	197	0.93
chr15_91913436_91913763	0.38	SV2B	synaptic vesicle glycoprotein 2B	144499	0.04
chr19_16510197_16510348	0.38	ENSG00000243745	.	502	0.73
chr1_109186051_109186202	0.38	HENMT1	HEN1 methyltransferase homolog 1 (Arabidopsis)	17551	0.18
chr3_171151213_171151364	0.38	ENSG00000222506	.	6027	0.25
chr8_141581579_141581781	0.38	AGO2	argonaute RISC catalytic component 2	34307	0.17
chr17_33849169_33849564	0.38	RP11-1094M14.5		12077	0.11
chr2_225807974_225808446	0.38	DOCK10	dedicator of cytokinesis 10	3572	0.36
chr10_28551540_28551691	0.38	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	17456	0.24
chr5_169077234_169077385	0.37	DOCK2	dedicator of cytokinesis 2	13058	0.25
chr1_31215727_31215937	0.37	ENSG00000264773	.	3753	0.19
chr8_19612580_19612819	0.37	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	2117	0.43
chr15_32665699_32665938	0.37	ENSG00000221444	.	19855	0.11
chr3_71530793_71531298	0.37	ENSG00000221264	.	60195	0.13
chr13_49070475_49070829	0.37	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	36561	0.19
chr2_205832841_205832992	0.37	PARD3B	par-3 family cell polarity regulator beta	422193	0.01
chr7_38347695_38347941	0.37	STARD3NL	STARD3 N-terminal like	129821	0.05
chr19_16264433_16264584	0.37	HSH2D	hematopoietic SH2 domain containing	9962	0.12
chr10_70821047_70821368	0.37	SRGN	serglycin	26667	0.16
chr6_152954903_152955054	0.37	SYNE1	spectrin repeat containing, nuclear envelope 1	3008	0.33
chr11_82885515_82885671	0.37	PCF11	PCF11 cleavage and polyadenylation factor subunit	3300	0.2
chr11_44764562_44764713	0.37	TSPAN18	tetraspanin 18	15913	0.27
chr2_192435451_192435695	0.37	NABP1	nucleic acid binding protein 1	107289	0.07
chr2_29236792_29237319	0.37	FAM179A	family with sequence similarity 179, member A	4072	0.19
chr1_100832547_100832698	0.37	ENSG00000216067	.	11709	0.18
chr3_30687567_30687843	0.37	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	39612	0.19
chr7_55535980_55536327	0.37	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	47617	0.16
chr12_92899152_92899351	0.37	ENSG00000238865	.	39512	0.17
chr22_23164837_23164988	0.36	IGLV2-8	immunoglobulin lambda variable 2-8	241	0.53
chr2_135003858_135004122	0.36	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	7840	0.25
chr19_39139307_39139802	0.36	ACTN4	actinin, alpha 4	1176	0.36
chr4_38656444_38656624	0.36	KLF3	Kruppel-like factor 3 (basic)	9283	0.18
chr1_90093588_90093765	0.36	RP11-413E1.4		1608	0.34
chr6_117922044_117922316	0.36	GOPC	golgi-associated PDZ and coiled-coil motif containing	1347	0.54
chr2_198150239_198150434	0.36	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	16907	0.16
chr3_128835058_128835443	0.36	RAB43	RAB43, member RAS oncogene family	5374	0.13
chr15_25670881_25671032	0.36	ENSG00000224078	.	7875	0.14
chr14_93124277_93124612	0.36	RIN3	Ras and Rab interactor 3	5598	0.29
chr2_240261025_240261176	0.36	ENSG00000264292	.	12399	0.18
chr17_65433675_65433892	0.36	ENSG00000244610	.	19623	0.12
chr10_11233804_11233955	0.36	RP3-323N1.2		20540	0.2
chr5_148739025_148739272	0.36	PCYOX1L	prenylcysteine oxidase 1 like	1578	0.23
chr5_173116619_173117186	0.36	ENSG00000263401	.	40179	0.18
chr3_128519253_128519404	0.36	RAB7A	RAB7A, member RAS oncogene family	5126	0.2
chr2_233924263_233924811	0.36	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	140	0.96
chr6_106562767_106563027	0.36	RP1-134E15.3		14882	0.22
chr5_80148572_80148723	0.36	CTC-459I6.1		100152	0.07
chr2_182303462_182303613	0.36	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	18397	0.27
chr18_46311251_46311510	0.35	RP11-484L8.1		49761	0.15
chr10_112294065_112294216	0.35	SMC3	structural maintenance of chromosomes 3	33309	0.13
chr14_98689187_98689819	0.35	ENSG00000222066	.	108584	0.07
chr18_13612636_13612881	0.35	LDLRAD4	low density lipoprotein receptor class A domain containing 4	140	0.93
chr1_38057574_38057725	0.35	GNL2	guanine nucleotide binding protein-like 2 (nucleolar)	3873	0.18
chr10_8287688_8287886	0.35	GATA3	GATA binding protein 3	191018	0.03
chr3_18766132_18766453	0.35	ENSG00000228956	.	20944	0.29
chr5_54319033_54319218	0.35	ESM1	endothelial cell-specific molecule 1	626	0.41
chr10_14585772_14586067	0.35	FAM107B	family with sequence similarity 107, member B	4750	0.28
chr6_53198686_53199165	0.35	ELOVL5	ELOVL fatty acid elongase 5	14662	0.2
chr2_136720223_136720444	0.35	AC093391.2		22413	0.18
chr17_76006574_76006749	0.35	TNRC6C	trinucleotide repeat containing 6C	5524	0.22
chr5_75701030_75701244	0.35	IQGAP2	IQ motif containing GTPase activating protein 2	888	0.72
chr6_6609840_6610222	0.35	LY86-AS1	LY86 antisense RNA 1	12897	0.24
chr7_150381547_150381741	0.35	GIMAP2	GTPase, IMAP family member 2	1144	0.47
chr1_24851664_24851815	0.35	ENSG00000266551	.	4465	0.19
chr1_197359929_197360312	0.35	CRB1	crumbs homolog 1 (Drosophila)	22839	0.23
chr4_40213506_40213657	0.35	RHOH	ras homolog family member H	11617	0.22
chr2_48116432_48116617	0.35	FBXO11	F-box protein 11	666	0.75
chr11_118085246_118085456	0.35	AMICA1	adhesion molecule, interacts with CXADR antigen 1	255	0.9
chr5_156700131_156700282	0.35	CYFIP2	cytoplasmic FMR1 interacting protein 2	3844	0.18
chr6_143246602_143246811	0.34	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	19632	0.24
chr6_109694572_109695063	0.34	CD164	CD164 molecule, sialomucin	8086	0.15
chr5_174949201_174949465	0.34	SFXN1	sideroflexin 1	43738	0.15
chr9_107877201_107877485	0.34	ENSG00000201583	.	18306	0.27
chr21_15900594_15900993	0.34	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	17869	0.23
chr15_31561641_31561994	0.34	KLF13	Kruppel-like factor 13	57241	0.15
chr22_45737116_45737267	0.34	FAM118A	family with sequence similarity 118, member A	11666	0.19
chr14_35884998_35885149	0.34	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	11121	0.26
chr11_117688467_117688621	0.34	DSCAML1	Down syndrome cell adhesion molecule like 1	304	0.69
chr9_104331960_104332111	0.34	ENSG00000265068	.	19982	0.15
chr12_104913670_104913898	0.34	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	63005	0.12
chr10_14766612_14766763	0.34	FAM107B	family with sequence similarity 107, member B	50209	0.13
chr14_34489429_34489580	0.34	EGLN3-AS1	EGLN3 antisense RNA 1	19799	0.22
chrX_78363858_78364080	0.34	GPR174	G protein-coupled receptor 174	62500	0.15
chr16_80598143_80598326	0.34	RP11-525K10.3		1202	0.45
chr14_99726122_99726406	0.34	AL109767.1		3021	0.29
chr1_145610403_145610620	0.34	POLR3C	polymerase (RNA) III (DNA directed) polypeptide C (62kD)	373	0.56
chr20_2802310_2802523	0.34	TMEM239	transmembrane protein 239	5437	0.13
chr10_32659855_32660006	0.34	EPC1	enhancer of polycomb homolog 1 (Drosophila)	7796	0.14
chr13_42041616_42041767	0.34	RGCC	regulator of cell cycle	9996	0.16
chr21_19159790_19160121	0.34	AL109761.5		5850	0.25
chr5_156599175_156599334	0.34	FAM71B	family with sequence similarity 71, member B	5979	0.14
chr3_16852643_16852936	0.33	PLCL2	phospholipase C-like 2	73663	0.11
chr17_45738481_45738632	0.33	KPNB1	karyopherin (importin) beta 1	4265	0.15
chr11_2322599_2322950	0.33	C11orf21	chromosome 11 open reading frame 21	369	0.53
chr5_67578609_67578791	0.33	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	2565	0.41
chr11_2469500_2469651	0.33	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	3354	0.19
chr8_134084181_134084461	0.33	SLA	Src-like-adaptor	11718	0.24
chr2_135005561_135006113	0.33	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	5993	0.26
chr2_204597152_204597390	0.33	CD28	CD28 molecule	25855	0.18
chr18_72041117_72041435	0.33	C18orf63	chromosome 18 open reading frame 63	58228	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of STAT6

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0030223	neutrophil differentiation(GO:0030223)
0.2	1.0	GO:0002423	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.4	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.2	GO:0002839	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1	0.2	GO:0002418	immune response to tumor cell(GO:0002418)
0.1	0.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.3	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.6	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.2	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.4	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.2	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.2	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.6	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.2	GO:0031063	regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.1	0.3	GO:0000281	mitotic cytokinesis(GO:0000281)
0.1	0.2	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.1	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.2	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.1	0.2	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1	0.2	GO:0060751	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.1	0.5	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.2	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.0	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.2	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.2	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.2	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.3	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.2	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.4	GO:0060324	face development(GO:0060324)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.2	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.4	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.0	0.2	GO:0050901	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.2	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.2	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.3	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.7	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0021778	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.4	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.1	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	1.7	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.0	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.2	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.0	0.1	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.2	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.2	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0007004	telomere maintenance via telomerase(GO:0007004)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0002335	mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.0	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.2	GO:0001510	RNA methylation(GO:0001510)
0.0	0.1	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.0	GO:0010534	regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0	0.0	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.4	GO:0032648	regulation of interferon-beta production(GO:0032648)
0.0	0.1	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0070266	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.0	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.0	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0061054	dermatome development(GO:0061054)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.2	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:0033151	V(D)J recombination(GO:0033151)
0.0	0.1	GO:0006907	pinocytosis(GO:0006907)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0016056	rhodopsin mediated signaling pathway(GO:0016056)
0.0	0.1	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.0	GO:0060298	positive regulation of sarcomere organization(GO:0060298)
0.0	0.1	GO:0070198	protein localization to chromosome, telomeric region(GO:0070198)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.0	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.3	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0032653	regulation of interleukin-10 production(GO:0032653)
0.0	0.1	GO:0048070	regulation of developmental pigmentation(GO:0048070)
0.0	0.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.2	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	0.0	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.5	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.0	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.0	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.2	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0043438	acetoacetic acid metabolic process(GO:0043438)
0.0	0.0	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:0042267	natural killer cell mediated immunity(GO:0002228) natural killer cell mediated cytotoxicity(GO:0042267)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.0	GO:0009804	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0	0.0	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.0	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0042503	tyrosine phosphorylation of Stat3 protein(GO:0042503)
0.0	0.0	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.3	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0	0.3	GO:0007030	Golgi organization(GO:0007030)
0.0	0.0	GO:1904936	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.1	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.0	0.0	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.0	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.3	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0031663	lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.0	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0071230	cellular response to amino acid stimulus(GO:0071230)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.2	GO:0030888	regulation of B cell proliferation(GO:0030888)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.0	GO:0032202	telomere assembly(GO:0032202) telomere formation via telomerase(GO:0032203)
0.0	0.0	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.2	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.0	GO:0034123	positive regulation of toll-like receptor signaling pathway(GO:0034123)
0.0	0.1	GO:0042461	photoreceptor cell development(GO:0042461) eye photoreceptor cell development(GO:0042462)
0.0	0.0	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.0	GO:0051712	positive regulation of killing of cells of other organism(GO:0051712)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.3	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.1	GO:0046676	negative regulation of insulin secretion(GO:0046676)
0.0	0.0	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.2	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.1	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.0	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.2	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0002281	macrophage activation involved in immune response(GO:0002281)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0031904	endosome lumen(GO:0031904)
0.1	0.2	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.3	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.4	GO:0001772	immunological synapse(GO:0001772)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0042627	chylomicron(GO:0042627)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.0	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.3	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.4	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.6	GO:0030863	cortical cytoskeleton(GO:0030863)
0.0	0.3	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.4	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	1.6	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.2	GO:0031672	A band(GO:0031672)
0.0	0.1	GO:0045257	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.2	GO:0070461	SAGA-type complex(GO:0070461)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.0	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.5	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.0	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.0	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.3	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.3	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.3	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.0	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.2	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.2	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.3	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.4	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.3	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.5	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.2	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.2	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.5	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.3	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.4	GO:0022829	wide pore channel activity(GO:0022829)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.5	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.7	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.6	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.2	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.2	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.0	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.0	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.0	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.0	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.2	GO:0015665	alcohol transmembrane transporter activity(GO:0015665)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0042287	MHC protein binding(GO:0042287)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.0	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.0	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.0	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.0	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.0	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.0	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.0	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.0	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.3	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	3.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	1.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	1.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.6	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.6	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.0	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.6	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.0	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.6	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.3	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.0	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.3	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.3	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.3	PID ATM PATHWAY	ATM pathway
0.0	0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	PID ALK1 PATHWAY	ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.1	0.8	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	1.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.7	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	2.0	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.6	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.5	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.0	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors