Project

ENCODE: H3K4me1 ChIP-Seq of primary human cells

Navigation

Downloads

Results for T

Z-value: 1.51

Motif logo

Transcription factors associated with T

Gene Symbol	Gene ID	Gene Info
T Ensembl NCBI GeneCards UniProt	ENSG00000164458.5	T

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_166587456_166587607	T	5343	0.245548	-0.66	5.3e-02	Click!
chr6_166581363_166581514	T	73	0.979056	0.27	4.8e-01	Click!
chr6_166587189_166587340	T	5076	0.248593	-0.23	5.5e-01	Click!
chr6_166580450_166580601	T	840	0.674117	-0.22	5.7e-01	Click!
chr6_166582078_166582256	T	8	0.982902	0.17	6.6e-01	Click!

Activity of the T motif across conditions

Conditions sorted by the z-value of the T motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_242048120_242048271	0.58	MTERFD2	MTERF domain containing 2	6448	0.15
chr8_11355510_11355697	0.56	BLK	B lymphoid tyrosine kinase	3704	0.19
chr6_20336837_20336988	0.53	E2F3	E2F transcription factor 3	65486	0.1
chr12_95383701_95383877	0.50	NDUFA12	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12	13687	0.24
chr15_38964800_38964977	0.48	C15orf53	chromosome 15 open reading frame 53	23911	0.24
chr20_37499471_37499622	0.46	ENSG00000240474	.	1867	0.36
chr14_99691163_99691558	0.46	AL109767.1		37925	0.16
chr14_99674686_99674837	0.45	AL162151.4		50008	0.14
chr20_43247520_43247671	0.45	Z97053.1	Uncharacterized protein	531	0.71
chr22_39487886_39488384	0.45	RP4-742C19.12		544	0.68
chr1_31214307_31214682	0.43	ENSG00000264773	.	2415	0.24
chr18_46929655_46929806	0.43	DYM	dymeclin	24711	0.14
chrX_46178338_46178489	0.42	KRBOX4	KRAB box domain containing 4	127879	0.06
chr2_204800043_204800332	0.42	ICOS	inducible T-cell co-stimulator	1284	0.58
chr14_92331526_92331677	0.41	TC2N	tandem C2 domains, nuclear	2272	0.32
chr6_74228779_74228930	0.40	EEF1A1	eukaryotic translation elongation factor 1 alpha 1	1887	0.21
chr14_22999356_22999596	0.40	TRAJ15	T cell receptor alpha joining 15	896	0.43
chr2_134974237_134974423	0.39	ENSG00000222921	.	14436	0.24
chr5_41866847_41866998	0.39	ENSG00000248668	.	3210	0.24
chr19_18195808_18195959	0.38	IL12RB1	interleukin 12 receptor, beta 1	1859	0.26
chr21_43821723_43821874	0.38	UBASH3A	ubiquitin associated and SH3 domain containing A	2210	0.21
chr3_60049608_60049759	0.38	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	92100	0.1
chr2_106494435_106494674	0.38	AC009505.2		20921	0.22
chr2_144174735_144174926	0.38	AC096558.1		63520	0.14
chr8_81913100_81913308	0.38	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	111099	0.06
chrX_19796721_19796978	0.37	SH3KBP1	SH3-domain kinase binding protein 1	21020	0.27
chr20_51025367_51025552	0.37	ZFP64	ZFP64 zinc finger protein	216934	0.02
chr17_39491497_39491648	0.37	KRT33A	keratin 33A	15492	0.08
chr14_22993904_22994105	0.37	TRAJ15	T cell receptor alpha joining 15	4576	0.13
chr12_55349877_55350141	0.37	TESPA1	thymocyte expressed, positive selection associated 1	6472	0.25
chr15_38869308_38869583	0.36	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	11669	0.2
chr6_45981324_45981508	0.36	CLIC5	chloride intracellular channel 5	2149	0.35
chr2_99223164_99223315	0.36	COA5	cytochrome c oxidase assembly factor 5	1716	0.31
chr7_100141762_100142078	0.36	AGFG2	ArfGAP with FG repeats 2	5038	0.1
chr16_57566018_57566169	0.36	CCDC102A	coiled-coil domain containing 102A	4418	0.17
chr11_68294838_68295084	0.36	PPP6R3	protein phosphatase 6, regulatory subunit 3	7918	0.18
chr19_47690366_47690533	0.35	ENSG00000265134	.	39750	0.1
chr7_150175374_150175525	0.35	GIMAP8	GTPase, IMAP family member 8	27731	0.14
chr5_150598571_150598820	0.35	CCDC69	coiled-coil domain containing 69	5011	0.2
chr18_48696508_48696738	0.35	MEX3C	mex-3 RNA binding family member C	26506	0.21
chr19_3024526_3024677	0.35	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	424	0.77
chr10_22931039_22931318	0.34	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	50536	0.17
chr13_114908435_114908661	0.34	RASA3	RAS p21 protein activator 3	10462	0.22
chr14_98638353_98638504	0.34	ENSG00000222066	.	159659	0.04
chr6_112060261_112060435	0.34	FYN	FYN oncogene related to SRC, FGR, YES	19083	0.24
chr19_2608004_2608206	0.34	CTC-265F19.2		3755	0.18
chr17_26902058_26902209	0.34	ALDOC	aldolase C, fructose-bisphosphate	799	0.32
chr12_67314860_67315011	0.34	GRIP1	glutamate receptor interacting protein 1	116969	0.07
chr6_17633492_17633643	0.34	ENSG00000206881	.	13803	0.19
chr16_89850957_89851182	0.34	FANCA	Fanconi anemia, complementation group A	31974	0.1
chr14_60744533_60744684	0.34	PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A	21128	0.2
chr6_143865508_143865659	0.34	PHACTR2	phosphatase and actin regulator 2	7601	0.17
chr11_73686038_73686668	0.34	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	1698	0.28
chr4_36241976_36242130	0.34	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	3508	0.25
chr12_122108111_122108262	0.33	MORN3	MORN repeat containing 3	626	0.72
chr1_89723727_89724122	0.33	RP4-620F22.2		2341	0.29
chr6_130454910_130455146	0.33	RP11-73O6.3		4313	0.28
chr17_9373024_9373241	0.33	RP11-565F19.4		5073	0.21
chr7_104877088_104877239	0.33	SRPK2	SRSF protein kinase 2	32299	0.18
chr8_27197054_27197628	0.33	PTK2B	protein tyrosine kinase 2 beta	13001	0.21
chr20_50018198_50018829	0.32	ENSG00000263645	.	24655	0.22
chrX_135707982_135708248	0.32	ENSG00000233093	.	13587	0.15
chr14_75580842_75580993	0.32	NEK9	NIMA-related kinase 9	12826	0.13
chr11_128197669_128197820	0.32	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	177545	0.03
chr1_59039851_59040096	0.32	TACSTD2	tumor-associated calcium signal transducer 2	3193	0.25
chr11_66648425_66648621	0.32	LRFN4	leucine rich repeat and fibronectin type III domain containing 4	23550	0.11
chr20_37499263_37499454	0.32	ENSG00000240474	.	2055	0.34
chr16_53492869_53493169	0.32	RBL2	retinoblastoma-like 2 (p130)	9031	0.16
chr21_40890346_40890497	0.32	SH3BGR	SH3 domain binding glutamic acid-rich protein	18672	0.18
chr9_95714104_95714255	0.32	FGD3	FYVE, RhoGEF and PH domain containing 3	4446	0.25
chr15_38869689_38869840	0.32	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	11988	0.2
chr2_219158817_219159019	0.32	TMBIM1	transmembrane BAX inhibitor motif containing 1	1609	0.23
chr10_73503024_73503387	0.32	C10orf105	chromosome 10 open reading frame 105	5624	0.22
chr3_66665999_66666150	0.32	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1	114639	0.07
chr10_32645306_32645520	0.32	RP11-135A24.2		9088	0.13
chr2_43397324_43397558	0.32	ZFP36L2	ZFP36 ring finger protein-like 2	56307	0.13
chr19_53281735_53281886	0.32	ZNF600	zinc finger protein 600	8206	0.16
chr11_45102394_45102692	0.32	PRDM11	PR domain containing 11	13021	0.28
chr14_55350751_55350902	0.32	ENSG00000265432	.	5915	0.2
chr6_45981609_45981857	0.32	CLIC5	chloride intracellular channel 5	1832	0.38
chr10_61613327_61613478	0.32	CCDC6	coiled-coil domain containing 6	53012	0.16
chr11_60814987_60815138	0.32	CD6	CD6 molecule	39056	0.11
chr19_46712739_46712890	0.31	IGFL1	IGF-like family member 1	20195	0.13
chr11_46376036_46376187	0.31	DGKZ	diacylglycerol kinase, zeta	6973	0.15
chr13_100312339_100312490	0.31	ENSG00000263615	.	17101	0.17
chr1_209849780_209849931	0.31	G0S2	G0/G1switch 2	1090	0.34
chr3_71755190_71755341	0.31	EIF4E3	eukaryotic translation initiation factor 4E family member 3	19261	0.21
chr11_19992448_19992599	0.31	NAV2-AS3	NAV2 antisense RNA 3	10360	0.24
chr2_100101428_100101579	0.31	REV1	REV1, polymerase (DNA directed)	4932	0.24
chr14_96593461_96593715	0.31	ENSG00000221236	.	9600	0.19
chr16_53534714_53534865	0.31	AKTIP	AKT interacting protein	548	0.79
chr22_42178568_42178888	0.31	MEI1	meiosis inhibitor 1	989	0.43
chr9_123667475_123667626	0.31	TRAF1	TNF receptor-associated factor 1	9300	0.19
chr1_204430993_204431895	0.31	PIK3C2B	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	5030	0.21
chr6_16621298_16621563	0.31	RP1-151F17.1		139939	0.05
chr3_71171219_71171437	0.31	FOXP1	forkhead box P1	8416	0.32
chr3_143573363_143573514	0.31	SLC9A9	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	6065	0.33
chr1_27685808_27685959	0.31	MAP3K6	mitogen-activated protein kinase kinase kinase 6	2921	0.16
chr1_32723117_32723278	0.31	LCK	lymphocyte-specific protein tyrosine kinase	6322	0.09
chr11_65847511_65847662	0.30	PACS1	phosphofurin acidic cluster sorting protein 1	3858	0.12
chr10_116299368_116299596	0.30	ABLIM1	actin binding LIM protein 1	12792	0.27
chr14_71431926_71432077	0.30	PCNX	pecanex homolog (Drosophila)	47747	0.18
chr14_64336454_64336669	0.30	SYNE2	spectrin repeat containing, nuclear envelope 2	16829	0.2
chr17_47824865_47825302	0.30	FAM117A	family with sequence similarity 117, member A	16410	0.14
chr22_23099763_23100005	0.30	ENSG00000207835	.	1301	0.12
chr17_47791186_47791337	0.30	SLC35B1	solute carrier family 35, member B1	4885	0.15
chr10_22990790_22990941	0.30	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	12172	0.28
chr7_129347135_129347286	0.30	ENSG00000212238	.	48896	0.11
chr12_75850308_75850552	0.30	GLIPR1	GLI pathogenesis-related 1	24030	0.16
chr15_92027521_92027672	0.30	SV2B	synaptic vesicle glycoprotein 2B	258496	0.02
chr16_50303522_50303851	0.30	ADCY7	adenylate cyclase 7	3224	0.27
chr16_12170626_12170806	0.30	RP11-276H1.3		13443	0.15
chr19_37821208_37821407	0.30	HKR1	HKR1, GLI-Kruppel zinc finger family member	4219	0.19
chr6_90944639_90944984	0.30	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	61650	0.13
chrX_102233319_102233470	0.30	LL0XNC01-237H1.3		37905	0.14
chr3_186760366_186760739	0.30	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	979	0.64
chr14_22686762_22687086	0.30	ENSG00000238634	.	76037	0.1
chr1_204419765_204419916	0.30	PIK3C2B	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	16634	0.17
chr10_11237002_11237580	0.30	RP3-323N1.2		23952	0.2
chr9_126031563_126031735	0.30	STRBP	spermatid perinuclear RNA binding protein	794	0.73
chr12_47756426_47756597	0.30	ENSG00000264906	.	1541	0.44
chr5_142762833_142762984	0.30	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	17509	0.28
chr1_185647202_185647437	0.30	ENSG00000201596	.	44005	0.15
chr14_99650324_99650558	0.29	AL162151.4		25688	0.22
chr10_82204643_82204906	0.29	TSPAN14	tetraspanin 14	9148	0.2
chr19_34801625_34801776	0.29	AC010504.2		48617	0.1
chr1_25251305_25251526	0.29	RUNX3	runt-related transcription factor 3	4197	0.26
chr13_50680377_50680528	0.29	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	24145	0.17
chrX_123476989_123477140	0.29	SH2D1A	SH2 domain containing 1A	3130	0.39
chr7_128146989_128147140	0.29	METTL2B	methyltransferase like 2B	13167	0.15
chr2_192070854_192071005	0.29	MYO1B	myosin IB	38982	0.17
chr20_56193359_56193625	0.29	ZBP1	Z-DNA binding protein 1	1958	0.39
chr11_130258236_130258459	0.29	ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8	40541	0.16
chr17_37930387_37930595	0.29	IKZF3	IKAROS family zinc finger 3 (Aiolos)	3987	0.16
chr17_37946623_37946846	0.29	IKZF3	IKAROS family zinc finger 3 (Aiolos)	12256	0.14
chr3_51707962_51708213	0.29	TEX264	testis expressed 264	2176	0.25
chr1_100910567_100910861	0.29	RP5-837M10.4		40839	0.15
chr1_160641988_160642241	0.29	RP11-404F10.2		688	0.65
chr7_8026293_8026444	0.29	AC006042.7		16834	0.17
chr5_56132858_56133125	0.29	ENSG00000238717	.	19984	0.15
chr1_224569842_224570078	0.29	ENSG00000266618	.	16053	0.14
chr1_167415328_167415582	0.29	RP11-104L21.2		12443	0.21
chr3_124738227_124738516	0.29	HEG1	heart development protein with EGF-like domains 1	17507	0.19
chr10_3822141_3822361	0.28	KLF6	Kruppel-like factor 6	5134	0.24
chr12_92421576_92421727	0.28	C12orf79	chromosome 12 open reading frame 79	109146	0.06
chr14_99950419_99950570	0.28	CCNK	cyclin K	2732	0.21
chr7_44091432_44091583	0.28	DBNL	drebrin-like	1664	0.2
chr16_84588398_84588684	0.28	TLDC1	TBC/LysM-associated domain containing 1	902	0.58
chr1_110050571_110050722	0.28	AMIGO1	adhesion molecule with Ig-like domain 1	1658	0.22
chr5_56121216_56121683	0.28	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	10048	0.18
chr10_33442227_33442397	0.28	NRP1	neuropilin 1	32271	0.18
chr4_122087231_122087498	0.28	TNIP3	TNFAIP3 interacting protein 3	1869	0.39
chr14_55761856_55762007	0.28	FBXO34	F-box protein 34	23059	0.2
chr4_40278360_40278573	0.28	CHRNA9	cholinergic receptor, nicotinic, alpha 9 (neuronal)	58880	0.11
chr19_10254387_10254800	0.28	EIF3G	eukaryotic translation initiation factor 3, subunit G	24015	0.07
chr1_235656699_235656850	0.28	B3GALNT2	beta-1,3-N-acetylgalactosaminyltransferase 2	10948	0.24
chr8_28886696_28886847	0.28	ENSG00000200719	.	19350	0.14
chr16_28216579_28216730	0.28	XPO6	exportin 6	6143	0.19
chr6_131946506_131946657	0.28	MED23	mediator complex subunit 23	2619	0.22
chr9_31260566_31260717	0.28	ENSG00000211510	.	486415	0.01
chr21_36396835_36397047	0.28	RUNX1	runt-related transcription factor 1	24521	0.28
chr6_139353645_139353867	0.28	ABRACL	ABRA C-terminal like	3777	0.29
chr2_204598538_204598689	0.28	CD28	CD28 molecule	27197	0.18
chr1_67886961_67887112	0.28	ENSG00000223263	.	4139	0.24
chr2_23754728_23754879	0.28	AC011239.1	Uncharacterized protein	7589	0.31
chr1_121311422_121311588	0.27	FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)	375568	0.01
chr3_18531533_18531684	0.27	ENSG00000228956	.	24124	0.22
chr1_185537982_185538176	0.27	ENSG00000207108	.	61581	0.12
chr3_63966450_63966601	0.27	ATXN7	ataxin 7	13105	0.13
chr10_126404133_126404651	0.27	FAM53B-AS1	FAM53B antisense RNA 1	11639	0.18
chr6_159216997_159217220	0.27	EZR-AS1	EZR antisense RNA 1	21935	0.15
chr22_38221629_38221780	0.27	GALR3	galanin receptor 3	2315	0.15
chr17_56418390_56418541	0.27	BZRAP1-AS1	BZRAP1 antisense RNA 1	3746	0.13
chr3_27941916_27942067	0.27	EOMES	eomesodermin	177785	0.03
chr7_151531263_151531414	0.27	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	19412	0.16
chr9_33443593_33443744	0.27	AQP3	aquaporin 3 (Gill blood group)	3941	0.18
chr1_204422098_204422254	0.27	PIK3C2B	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	14298	0.18
chr19_13302093_13302244	0.27	CTC-250I14.6		37161	0.09
chr2_42411006_42411225	0.27	AC083949.1		13674	0.22
chr9_100947774_100947925	0.27	CORO2A	coronin, actin binding protein, 2A	7073	0.22
chr17_73900419_73900598	0.27	MRPL38	mitochondrial ribosomal protein L38	986	0.32
chr18_3058642_3058842	0.27	ENSG00000252258	.	33178	0.13
chr1_111998667_111998818	0.27	ATP5F1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1	6636	0.09
chr14_35630572_35630723	0.27	KIAA0391	KIAA0391	38682	0.15
chr2_97629977_97630128	0.27	ENSG00000252845	.	7500	0.15
chr17_26663097_26663248	0.26	TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	321	0.61
chr2_222394469_222394620	0.26	ENSG00000221432	.	10167	0.23
chr16_74657084_74657235	0.26	GLG1	golgi glycoprotein 1	16147	0.19
chr10_52273258_52273409	0.26	RP11-512N4.2		40759	0.15
chr21_35456731_35456882	0.26	SLC5A3	solute carrier family 5 (sodium/myo-inositol cotransporter), member 3	10936	0.21
chr1_231747664_231747892	0.26	LINC00582	long intergenic non-protein coding RNA 582	58	0.98
chr1_79105880_79106031	0.26	IFI44	interferon-induced protein 44	9561	0.21
chr5_156675096_156675274	0.26	ENSG00000222086	.	12876	0.13
chr21_43841198_43841406	0.26	ENSG00000252619	.	3600	0.17
chr3_71488238_71488635	0.26	ENSG00000221264	.	102804	0.07
chr5_53898057_53898208	0.26	SNX18	sorting nexin 18	84539	0.1
chr16_79446696_79446975	0.26	ENSG00000222244	.	148484	0.04
chr5_156593720_156593871	0.26	FAM71B	family with sequence similarity 71, member B	520	0.7
chr2_213966551_213966702	0.26	IKZF2	IKAROS family zinc finger 2 (Helios)	46727	0.18
chr21_46501868_46502019	0.26	ADARB1	adenosine deaminase, RNA-specific, B1	7428	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of T

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.2	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.4	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1	0.4	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.1	0.3	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.3	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.3	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.5	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.3	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.2	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.2	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.3	GO:0007097	nuclear migration(GO:0007097)
0.1	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.2	GO:0019731	antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.0	GO:0010755	regulation of plasminogen activation(GO:0010755)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.2	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	0.0	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.1	GO:0002335	mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.3	GO:0002837	positive regulation of response to biotic stimulus(GO:0002833) regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.2	GO:0045354	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0	0.2	GO:0021684	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.3	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.6	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.2	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.0	0.2	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.2	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.3	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.0	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.4	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.2	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.2	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.2	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.2	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.0	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.1	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.2	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.0	GO:0033622	integrin activation(GO:0033622)
0.0	0.1	GO:0032261	purine nucleotide salvage(GO:0032261)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.2	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.2	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.0	0.1	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.2	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0072224	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.0	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	1.3	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.0	GO:0052169	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.2	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.0	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.2	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.2	GO:0051806	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.4	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.1	GO:0050884	neuromuscular process controlling posture(GO:0050884)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.3	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.0	GO:0097502	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.0	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0090196	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.1	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.0	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.1	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:1901984	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.1	GO:0042921	corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	0.2	GO:0002920	regulation of humoral immune response(GO:0002920)
0.0	0.0	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0002832	negative regulation of response to biotic stimulus(GO:0002832)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0071501	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.0	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.0	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.1	GO:0006582	melanin metabolic process(GO:0006582)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.4	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.0	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.1	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.0	0.0	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.0	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.0	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.1	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.2	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.2	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.0	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.3	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.2	GO:0010921	regulation of phosphatase activity(GO:0010921) regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.2	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0006984	ER-nucleus signaling pathway(GO:0006984)
0.0	0.2	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.2	GO:0003407	neural retina development(GO:0003407)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.5	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0018216	peptidyl-arginine methylation(GO:0018216)
0.0	0.0	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314) protein K6-linked ubiquitination(GO:0085020)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0032627	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0000154	rRNA modification(GO:0000154)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.2	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:1902749	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.1	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.2	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.1	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.0	GO:0098900	negative regulation of action potential(GO:0045759) regulation of action potential(GO:0098900)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0007140	male meiosis(GO:0007140)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.0	GO:0001787	natural killer cell proliferation(GO:0001787)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.0	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.2	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0	0.0	GO:0042508	tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.0	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.0	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.0	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.0	GO:0032613	interleukin-10 production(GO:0032613)
0.0	0.1	GO:0000303	response to superoxide(GO:0000303)
0.0	0.1	GO:0071482	cellular response to light stimulus(GO:0071482)
0.0	0.0	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.2	GO:0051350	negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0	0.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.2	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.0	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.0	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.0	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.0	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.0	GO:0003157	endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160)
0.0	0.4	GO:0034341	response to interferon-gamma(GO:0034341)
0.0	0.0	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:1901663	quinone biosynthetic process(GO:1901663)
0.0	0.0	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.1	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.0	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.3	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0070695	FHF complex(GO:0070695)
0.1	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.3	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.4	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0043159	acrosomal matrix(GO:0043159)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.2	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.3	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.0	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:0071564	npBAF complex(GO:0071564)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.0	GO:0033011	perinuclear theca(GO:0033011)
0.0	0.6	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.2	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.0	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.0	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.0	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.4	GO:0015030	Cajal body(GO:0015030)
0.0	0.0	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.0	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.2	GO:0032420	stereocilium(GO:0032420)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.5	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.0	GO:0005697	telomerase holoenzyme complex(GO:0005697)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.5	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.4	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.5	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0031013	troponin I binding(GO:0031013)
0.0	0.3	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.4	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.3	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.2	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.2	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.2	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0	0.3	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.6	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.3	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0019239	deaminase activity(GO:0019239)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.2	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.0	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.4	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.2	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.3	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.3	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.4	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.4	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.2	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.2	GO:0019210	kinase inhibitor activity(GO:0019210)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.4	GO:0036459	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.0	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.1	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.0	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.2	GO:0002039	p53 binding(GO:0002039)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.0	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.0	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.0	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	1.2	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.7	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
1.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.4	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.4	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
1.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.0	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.4	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.4	PID BCR 5PATHWAY	BCR signaling pathway
0.3	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.6	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.6	PID LKB1 PATHWAY	LKB1 signaling events
0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.3	PID BARD1 PATHWAY	BARD1 signaling events
0.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4	PID P53 REGULATION PATHWAY	p53 pathway
0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.4	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	1.0	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.5	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.9	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.6	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.0	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.3	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.9	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.8	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.1	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.0	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.6	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.1	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.5	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	0.1	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
0.0	0.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.1	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.6	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants

Results for T

Z-value: 1.51

Motif logo

Transcription factors associated with T

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the T motif across conditions

Conditions sorted by the z-value of the T motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of T

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: