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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for TBX19

Z-value: 1.39

Motif logo

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Transcription factors associated with TBX19

Gene Symbol Gene ID Gene Info
TBX19
ENSG00000143178.8 T-box transcription factor 19

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_168290494_168290645TBX19237070.189074-0.481.9e-01Click!
chr1_168289944_168290095TBX19231570.190319-0.274.8e-01Click!
chr1_168271269_168271420TBX1944820.246188-0.078.5e-01Click!
chr1_168254552_168254703TBX1943490.233789-0.001.0e+00Click!

Activity of the TBX19 motif across conditions

Conditions sorted by the z-value of the TBX19 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_46530833_46530984 0.61 PGLYRP1
 peptidoglycan recognition protein 1
 4585
 0.14
chr20_13838142_13838293 0.40 NDUFAF5
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
 72521
 0.1
chr5_141307102_141307397 0.30 KIAA0141
 KIAA0141
 3774
 0.18
chr3_121386721_121386872 0.29 HCLS1
 hematopoietic cell-specific Lyn substrate 1
 7038
 0.16
chr14_65165014_65165274 0.28 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
 5676
 0.24
chr15_70755158_70755354 0.28 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 239364
 0.02
chr21_43614804_43615118 0.28 ABCG1
 ATP-binding cassette, sub-family G (WHITE), member 1
 4838
 0.21
chr10_82421596_82421747 0.27 SH2D4B
 SH2 domain containing 4B
 121096
 0.06
chr2_198150239_198150434 0.26 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 16907
 0.16
chr1_38958842_38958993 0.26 ENSG00000200796
 .
 96586
 0.08
chr9_92272620_92272771 0.26 GADD45G
 growth arrest and DNA-damage-inducible, gamma
 52742
 0.17
chr8_97662802_97662953 0.26 CPQ
 carboxypeptidase Q
 5274
 0.31
chr17_40994693_40994844 0.25 AOC2
 amine oxidase, copper containing 2 (retina-specific)
 1849
 0.16
chr14_91167266_91167417 0.25 RP11-661G16.2
3664
 0.23
chr8_59068204_59068401 0.25 FAM110B
 family with sequence similarity 110, member B
 161189
 0.04
chr14_90032899_90033050 0.25 FOXN3-AS2
 FOXN3 antisense RNA 2
 9586
 0.17
chr2_118814167_118814318 0.25 INSIG2
 insulin induced gene 2
 31808
 0.13
chr1_212000871_212001169 0.25 RP11-552D8.1
2168
 0.25
chrX_134441517_134441668 0.25 ZNF75D
 zinc finger protein 75D
 11633
 0.21
chr15_86078641_86078893 0.25 AKAP13
 A kinase (PRKA) anchor protein 13
 8504
 0.21
chr20_31898220_31898371 0.25 BPIFB1
 BPI fold containing family B, member 1
 27354
 0.14
chr17_74246966_74247117 0.24 RNF157
 ring finger protein 157
 10587
 0.13
chr15_99488986_99489137 0.24 IGF1R
 insulin-like growth factor 1 receptor
 21232
 0.19
chr16_15883480_15883631 0.24 AF001548.6
48547
 0.1
chr18_74188097_74188669 0.24 ZNF516
 zinc finger protein 516
 14352
 0.17
chr2_144450054_144450205 0.24 RP11-434H14.1
9621
 0.23
chr4_184318912_184319063 0.24 ENSG00000263395
 .
 13281
 0.17
chr20_58675900_58676156 0.24 C20orf197
 chromosome 20 open reading frame 197
 45048
 0.18
chr1_52105044_52105195 0.24 OSBPL9
 oxysterol binding protein-like 9
 22338
 0.19
chr18_43578628_43579079 0.23 ENSG00000222179
 .
 8942
 0.2
chr1_32558443_32558736 0.23 ENSG00000266203
 .
 6039
 0.13
chr21_15810558_15810709 0.23 HSPA13
 heat shock protein 70kDa family, member 13
 55125
 0.15
chr8_10028580_10028731 0.23 MSRA
 methionine sulfoxide reductase A
 75418
 0.1
chr3_196404146_196404677 0.23 ENSG00000201441
 .
 31424
 0.1
chr3_131537149_131537300 0.23 CPNE4
 copine IV
 107201
 0.07
chr2_202074857_202075031 0.23 CASP8
 caspase 8, apoptosis-related cysteine peptidase
 23222
 0.14
chr1_180238065_180238216 0.23 RP5-1180C10.2
5676
 0.25
chr12_110435362_110435658 0.23 GIT2
 G protein-coupled receptor kinase interacting ArfGAP 2
 1316
 0.37
chr20_24270958_24271313 0.23 ENSG00000200231
 .
 53244
 0.17
chrX_65232472_65232880 0.22 ENSG00000207939
 .
 6036
 0.22
chr6_5828955_5829300 0.22 ENSG00000239472
 .
 89950
 0.09
chr14_91592357_91592508 0.22 ENSG00000221102
 .
 337
 0.64
chr15_42662964_42663115 0.22 CAPN3
 calpain 3, (p94)
 11254
 0.16
chr20_35586845_35586996 0.22 SAMHD1
 SAM domain and HD domain 1
 6674
 0.24
chr18_74211925_74212216 0.22 RP11-17M16.1
 uncharacterized protein LOC400658
 4593
 0.19
chr22_22304135_22304332 0.22 PPM1F
 protein phosphatase, Mg2+/Mn2+ dependent, 1F
 2970
 0.16
chr14_64214575_64214726 0.22 ENSG00000252749
 .
 11488
 0.18
chr11_78109102_78109366 0.22 RP11-452H21.2
10127
 0.18
chr2_69063618_69063857 0.22 AC097495.2
1601
 0.39
chr3_71376865_71377143 0.22 FOXP1
 forkhead box P1
 23093
 0.23
chr6_131889933_131890084 0.22 ARG1
 arginase 1
 4276
 0.25
chr4_185772755_185773053 0.21 ENSG00000266698
 .
 640
 0.72
chr1_172410212_172410374 0.21 PIGC
 phosphatidylinositol glycan anchor biosynthesis, class C
 2907
 0.24
chr9_95555847_95555998 0.21 ANKRD19P
 ankyrin repeat domain 19, pseudogene
 15971
 0.16
chr7_156842429_156842580 0.21 MNX1-AS1
 MNX1 antisense RNA 1 (head to head)
 39005
 0.12
chr1_63931746_63931897 0.21 ITGB3BP
 integrin beta 3 binding protein (beta3-endonexin)
 57030
 0.09
chr2_42979198_42979349 0.21 OXER1
 oxoeicosanoid (OXE) receptor 1
 12128
 0.21
chr2_68652846_68653082 0.21 FBXO48
 F-box protein 48
 41426
 0.12
chr18_74807316_74807807 0.21 MBP
 myelin basic protein
 9656
 0.29
chr12_132366972_132367123 0.21 ULK1
 unc-51 like autophagy activating kinase 1
 12149
 0.17
chr6_116784453_116784778 0.21 RP1-93H18.6
240
 0.83
chr4_48239820_48240029 0.21 TEC
 tec protein tyrosine kinase
 31957
 0.18
chr17_4158247_4158398 0.21 ANKFY1
 ankyrin repeat and FYVE domain containing 1
 8820
 0.18
chr2_207025046_207025348 0.21 EEF1B2
 eukaryotic translation elongation factor 1 beta 2
 866
 0.28
chr14_51292294_51292451 0.21 NIN
 ninein (GSK3B interacting protein)
 3598
 0.17
chr2_28843080_28843618 0.20 PLB1
 phospholipase B1
 10104
 0.21
chr3_154802157_154802308 0.20 MME
 membrane metallo-endopeptidase
 499
 0.88
chr4_79597785_79597936 0.20 ENSG00000238816
 .
 36606
 0.16
chr1_93495068_93495341 0.20 ENSG00000251837
 .
 2141
 0.21
chr1_234899568_234899784 0.20 ENSG00000201638
 .
 74044
 0.11
chr2_198971191_198971372 0.20 PLCL1
 phospholipase C-like 1
 22745
 0.28
chr8_131021838_131021989 0.20 ENSG00000264653
 .
 1214
 0.43
chr8_39806379_39806556 0.20 IDO2
 indoleamine 2,3-dioxygenase 2
 218
 0.93
chr12_57106930_57107081 0.20 NACA
 nascent polypeptide-associated complex alpha subunit
 6379
 0.13
chr2_239295864_239296015 0.20 ENSG00000202099
 .
 25344
 0.14
chr2_128938668_128938819 0.20 UGGT1
 UDP-glucose glycoprotein glucosyltransferase 1
 1383
 0.51
chr1_152022964_152023546 0.20 S100A11
 S100 calcium binding protein A11
 13744
 0.14
chrX_119670283_119670616 0.20 ENSG00000272179
 .
 7721
 0.2
chrX_12928349_12928500 0.20 TLR8-AS1
 TLR8 antisense RNA 1
 1972
 0.31
chr1_168416183_168416334 0.20 ENSG00000207974
 .
 71496
 0.11
chr7_75505515_75505666 0.20 RHBDD2
 rhomboid domain containing 2
 2676
 0.23
chr3_151592281_151592432 0.20 SUCNR1
 succinate receptor 1
 925
 0.64
chr4_14913654_14913805 0.20 CPEB2
 cytoplasmic polyadenylation element binding protein 2
 90569
 0.1
chr20_35470625_35470932 0.20 SOGA1
 suppressor of glucose, autophagy associated 1
 17498
 0.15
chr14_71434574_71434725 0.20 PCNX
 pecanex homolog (Drosophila)
 45099
 0.19
chr1_169572243_169572400 0.19 SELP
 selectin P (granule membrane protein 140kDa, antigen CD62)
 16136
 0.19
chr12_95032892_95033043 0.19 TMCC3
 transmembrane and coiled-coil domain family 3
 11371
 0.26
chr3_39291368_39291710 0.19 CX3CR1
 chemokine (C-X3-C motif) receptor 1
 29986
 0.16
chr20_4797995_4798146 0.19 RASSF2
 Ras association (RalGDS/AF-6) domain family member 2
 2301
 0.31
chr8_124145367_124145518 0.19 TBC1D31
 TBC1 domain family, member 31
 32249
 0.11
chr22_17597863_17598182 0.19 CECR6
 cat eye syndrome chromosome region, candidate 6
 4121
 0.17
chr1_60015308_60015459 0.19 FGGY
 FGGY carbohydrate kinase domain containing
 4207
 0.36
chr14_65200681_65201005 0.19 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
 3890
 0.26
chr7_41525377_41525528 0.19 INHBA-AS1
 INHBA antisense RNA 1
 208062
 0.03
chr1_185390714_185391145 0.19 ENSG00000252407
 .
 12447
 0.26
chr2_46116515_46116666 0.19 PRKCE
 protein kinase C, epsilon
 111451
 0.07
chr20_49073611_49073762 0.19 ENSG00000244376
 .
 27666
 0.17
chr6_160363198_160363349 0.19 IGF2R
 insulin-like growth factor 2 receptor
 26858
 0.17
chr2_135953447_135953598 0.19 ENSG00000208308
 .
 59324
 0.14
chr9_104203183_104203334 0.19 ALDOB
 aldolase B, fructose-bisphosphate
 5153
 0.17
chr11_6742912_6743421 0.19 GVINP1
 GTPase, very large interferon inducible pseudogene 1
 55
 0.96
chr17_42761038_42761322 0.19 CCDC43
 coiled-coil domain containing 43
 5913
 0.13
chr14_65173299_65173599 0.19 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
 2134
 0.36
chr10_15713490_15713641 0.19 ITGA8
 integrin, alpha 8
 48559
 0.18
chr13_100138979_100139130 0.19 LINC00449
 long intergenic non-protein coding RNA 449
 14252
 0.16
chr2_135165435_135165594 0.19 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 153684
 0.04
chr1_175158282_175158496 0.19 KIAA0040
 KIAA0040
 3501
 0.33
chr20_23142717_23142901 0.19 ENSG00000201527
 .
 1201
 0.54
chr3_5054013_5054242 0.19 BHLHE40-AS1
 BHLHE40 antisense RNA 1
 32481
 0.16
chr10_75305750_75305901 0.19 ENSG00000207327
 .
 16910
 0.12
chr14_74365658_74365809 0.19 ZNF410
 zinc finger protein 410
 4670
 0.11
chr22_35725194_35725345 0.19 ENSG00000266320
 .
 6364
 0.17
chr1_229161136_229161564 0.19 RP5-1061H20.5
201959
 0.02
chr6_108958559_108958710 0.19 FOXO3
 forkhead box O3
 18915
 0.27
chr2_69006771_69007110 0.18 ARHGAP25
 Rho GTPase activating protein 25
 4868
 0.27
chr18_74138582_74138815 0.18 ZNF516
 zinc finger protein 516
 47830
 0.13
chr11_75488134_75488285 0.18 CTD-2530H12.2
1260
 0.29
chr8_20056663_20056818 0.18 ATP6V1B2
 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
 1790
 0.34
chr4_80499592_80499743 0.18 OR7E94P
 olfactory receptor, family 7, subfamily E, member 94 pseudogene
 9617
 0.31
chr3_151081140_151081291 0.18 P2RY12
 purinergic receptor P2Y, G-protein coupled, 12
 21385
 0.16
chr9_114661606_114661757 0.18 UGCG
 UDP-glucose ceramide glucosyltransferase
 2635
 0.29
chr1_226223326_226223530 0.18 H3F3A
 H3 histone, family 3A
 26124
 0.13
chr2_228354322_228354473 0.18 AGFG1
 ArfGAP with FG repeats 1
 17309
 0.19
chr6_7312394_7312749 0.18 SSR1
 signal sequence receptor, alpha
 836
 0.65
chr10_94002812_94003219 0.18 CPEB3
 cytoplasmic polyadenylation element binding protein 3
 12
 0.98
chr11_63274107_63274394 0.18 LGALS12
 lectin, galactoside-binding, soluble, 12
 415
 0.81
chr8_141114736_141114887 0.18 C8orf17
 chromosome 8 open reading frame 17
 171395
 0.04
chr5_1503133_1503343 0.18 LPCAT1
 lysophosphatidylcholine acyltransferase 1
 20854
 0.2
chr1_155204670_155204827 0.18 ENSG00000216109
 .
 1880
 0.12
chr20_56878561_56878712 0.18 PPP4R1L
 protein phosphatase 4, regulatory subunit 1-like
 5859
 0.21
chr4_185182646_185182797 0.18 ENSG00000221523
 .
 5863
 0.22
chr2_7139293_7139444 0.18 RNF144A
 ring finger protein 144A
 2297
 0.38
chr15_91406561_91406712 0.18 FURIN
 furin (paired basic amino acid cleaving enzyme)
 5186
 0.12
chr6_152269247_152269414 0.18 ESR1
 estrogen receptor 1
 67538
 0.13
chr7_3786961_3787112 0.18 AC011284.3
103620
 0.08
chr2_216997149_216997386 0.18 XRCC5
 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
 23193
 0.18
chrX_10087005_10087156 0.18 CLCN4
 chloride channel, voltage-sensitive 4
 37944
 0.15
chr8_82065263_82065697 0.18 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 41177
 0.19
chr16_23877339_23877739 0.18 PRKCB
 protein kinase C, beta
 28995
 0.21
chr8_61609604_61609755 0.18 CHD7
 chromodomain helicase DNA binding protein 7
 17556
 0.26
chr3_43305774_43305925 0.18 SNRK
 SNF related kinase
 22155
 0.18
chr10_134068535_134068686 0.18 STK32C
 serine/threonine kinase 32C
 52108
 0.12
chr13_53601964_53602115 0.18 OLFM4
 olfactomedin 4
 855
 0.75
chr3_17040308_17040567 0.18 PLCL2
 phospholipase C-like 2
 11549
 0.24
chr1_225506705_225506856 0.18 DNAH14
 dynein, axonemal, heavy chain 14
 68415
 0.11
chr17_73965690_73965841 0.18 ACOX1
 acyl-CoA oxidase 1, palmitoyl
 9009
 0.09
chr19_51613185_51613336 0.18 CTU1
 cytosolic thiouridylase subunit 1
 1633
 0.2
chr9_7966540_7966691 0.18 TMEM261
 transmembrane protein 261
 166548
 0.04
chr5_96157488_96157872 0.18 ERAP1
 endoplasmic reticulum aminopeptidase 1
 13877
 0.14
chr2_202322766_202322917 0.17 STRADB
 STE20-related kinase adaptor beta
 6322
 0.19
chr10_11249572_11249747 0.17 RP3-323N1.2
36320
 0.17
chr22_19399369_19399520 0.17 HIRA
 histone cell cycle regulator
 19775
 0.1
chr19_41913601_41913801 0.17 BCKDHA
 branched chain keto acid dehydrogenase E1, alpha polypeptide
 2926
 0.12
chr2_103037979_103038143 0.17 IL18RAP
 interleukin 18 receptor accessory protein
 1915
 0.26
chr21_16579711_16579862 0.17 NRIP1
 nuclear receptor interacting protein 1
 142465
 0.05
chr2_85901507_85901658 0.17 SFTPB
 surfactant protein B
 5718
 0.14
chr19_43086596_43086747 0.17 CEACAM8
 carcinoembryonic antigen-related cell adhesion molecule 8
 12411
 0.18
chr21_34792697_34792848 0.17 IFNGR2
 interferon gamma receptor 2 (interferon gamma transducer 1)
 11854
 0.16
chr4_15666458_15666609 0.17 FBXL5
 F-box and leucine-rich repeat protein 5
 5043
 0.21
chr9_126440722_126440880 0.17 DENND1A
 DENN/MADD domain containing 1A
 26471
 0.21
chr8_123957813_123957964 0.17 RP11-557C18.3
56912
 0.1
chr7_37748458_37748609 0.17 GPR141
 G protein-coupled receptor 141
 25058
 0.2
chr19_42702815_42703281 0.17 ENSG00000265122
 .
 5818
 0.1
chr4_13622958_13623109 0.17 BOD1L1
 biorientation of chromosomes in cell division 1-like 1
 6314
 0.21
chr16_68923648_68923799 0.17 ENSG00000199979
 .
 4143
 0.21
chr7_42947190_42947341 0.17 C7orf25
 chromosome 7 open reading frame 25
 4244
 0.24
chr14_102319181_102319389 0.17 CTD-2017C7.1
13417
 0.17
chr21_15916640_15916923 0.17 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 1881
 0.42
chr10_30021965_30022179 0.17 SVIL
 supervillin
 2658
 0.33
chr1_109676026_109676177 0.17 KIAA1324
 KIAA1324
 19324
 0.11
chr2_136765754_136765905 0.17 AC093391.2
644
 0.76
chr1_6069612_6069763 0.17 KCNAB2
 potassium voltage-gated channel, shaker-related subfamily, beta member 2
 16673
 0.16
chr20_46354413_46354564 0.17 CTD-2653D5.1
47843
 0.14
chr4_6687814_6687965 0.17 AC093323.1
 Uncharacterized protein
 6300
 0.15
chr2_109883164_109883315 0.17 ENSG00000265965
 .
 46842
 0.18
chr8_48422326_48422477 0.17 RP11-697N18.4
17558
 0.25
chr4_81064069_81064253 0.17 PRDM8
 PR domain containing 8
 41278
 0.16
chr11_27379616_27379767 0.17 CCDC34
 coiled-coil domain containing 34
 5090
 0.29
chr16_84377709_84377860 0.17 ATP2C2
 ATPase, Ca++ transporting, type 2C, member 2
 24349
 0.15
chr11_73131309_73131460 0.17 RP11-809N8.4
15042
 0.16
chr10_6436483_6436634 0.17 DKFZP667F0711
44280
 0.18
chr5_98276963_98277114 0.17 ENSG00000200351
 .
 4587
 0.25
chr15_72660549_72660700 0.17 HEXA
 hexosaminidase A (alpha polypeptide)
 7561
 0.16
chr2_231074797_231075232 0.17 SP140
 SP140 nuclear body protein
 7188
 0.19
chr2_43643825_43643976 0.17 ENSG00000252804
 .
 8454
 0.29
chr17_53841712_53842007 0.17 PCTP
 phosphatidylcholine transfer protein
 9238
 0.26
chr5_111463867_111464018 0.17 ENSG00000238363
 .
 33240
 0.17
chr14_65460947_65461098 0.16 FNTB
 farnesyltransferase, CAAX box, beta
 7584
 0.12
chr10_3506996_3507147 0.16 RP11-184A2.3
286188
 0.01
chr14_55583593_55583744 0.16 LGALS3
 lectin, galactoside-binding, soluble, 3
 7160
 0.23
chr5_42631476_42631627 0.16 GHR
 growth hormone receptor
 65593
 0.13
chrX_30657144_30657355 0.16 GK
 glycerol kinase
 14227
 0.19
chr16_81962423_81962574 0.16 ENSG00000260682
 .
 33033
 0.17
chr13_99931097_99931381 0.16 GPR18
 G protein-coupled receptor 18
 17241
 0.18
chr12_104192450_104192601 0.16 RP11-650K20.2
20863
 0.13
chr16_53534714_53534865 0.16 AKTIP
 AKT interacting protein
 548
 0.79
chr12_95042694_95042845 0.16 TMCC3
 transmembrane and coiled-coil domain family 3
 1569
 0.51
chr16_3867727_3867878 0.16 CREBBP
 CREB binding protein
 36934
 0.16
chr17_45995658_45995845 0.16 RP11-6N17.3
14721
 0.09
chr15_68507516_68507667 0.16 CALML4
 calmodulin-like 4
 9174
 0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX19

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.2 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.2 GO:0001878 response to yeast(GO:0001878)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.0 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0021779 oligodendrocyte cell fate commitment(GO:0021779)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.0 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.4 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0046449 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.0 GO:0070508 sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.0 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0010872 regulation of cholesterol esterification(GO:0010872)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.0 0.0 GO:0060751 branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.0 GO:0048143 astrocyte activation(GO:0048143)
0.0 0.1 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.1 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.0 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.0 GO:0060192 negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0030540 female genitalia development(GO:0030540)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.0 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.0 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0034442 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.0 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.0 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.2 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.0 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.0 GO:0018101 protein citrullination(GO:0018101)
0.0 0.0 GO:1904729 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.0 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.0 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.0 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.0 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0 0.0 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.0 GO:1903504 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.0 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.0 GO:0032375 negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0 0.0 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.1 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0042891 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.0 GO:0000800 lateral element(GO:0000800)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.3 GO:0070492 oligosaccharide binding(GO:0070492)
0.1 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.2 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.0 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.0 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.0 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.0 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0031420 alkali metal ion binding(GO:0031420)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.5 PID IGF1 PATHWAY IGF1 pathway
0.0 0.4 PID EPO PATHWAY EPO signaling pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.0 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.0 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP