Project

ENCODE: H3K4me1 ChIP-Seq of primary human cells

Navigation

Downloads

Results for TBX2

Z-value: 1.13

Motif logo

Transcription factors associated with TBX2

Gene Symbol	Gene ID	Gene Info
TBX2 Ensembl NCBI GeneCards UniProt	ENSG00000121068.9	T-box transcription factor 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_59477041_59477307	TBX2	83	0.612123	-0.39	3.1e-01	Click!

Activity of the TBX2 motif across conditions

Conditions sorted by the z-value of the TBX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_640639_641593	2.22	RAB40C	RAB40C, member RAS oncogene family	784	0.37
chr14_105439124_105439578	0.53	AHNAK2	AHNAK nucleoprotein 2	5343	0.17
chr13_111033188_111033339	0.53	ENSG00000238629	.	33289	0.17
chr1_23158206_23158357	0.47	RP11-69E9.1		5061	0.21
chr5_64493902_64494516	0.46	ENSG00000207439	.	75013	0.12
chr2_47496531_47496728	0.45	EPCAM	epithelial cell adhesion molecule	75668	0.08
chr2_235934239_235934633	0.44	SH3BP4	SH3-domain binding protein 4	30952	0.26
chr20_33905876_33906027	0.43	FAM83C	family with sequence similarity 83, member C	25747	0.1
chr15_89644922_89645216	0.43	ABHD2	abhydrolase domain containing 2	603	0.72
chr3_156817192_156817343	0.43	ENSG00000201778	.	54070	0.11
chr19_6109054_6110118	0.41	CTB-66B24.1		253	0.82
chr8_42349258_42349610	0.41	SLC20A2	solute carrier family 20 (phosphate transporter), member 2	9327	0.2
chr3_115508519_115508795	0.41	ENSG00000243359	.	48058	0.19
chr3_65965340_65965491	0.41	ENSG00000202071	.	24200	0.16
chr4_10097090_10097875	0.41	ENSG00000264931	.	17166	0.14
chr13_111033026_111033177	0.40	ENSG00000238629	.	33451	0.17
chr10_4584081_4584405	0.39	ENSG00000207124	.	27099	0.26
chr7_93697701_93697852	0.39	BET1	Bet1 golgi vesicular membrane trafficking protein	64082	0.12
chr4_164462581_164462732	0.39	ENSG00000264535	.	18212	0.21
chr17_38500621_38501691	0.39	RARA	retinoic acid receptor, alpha	337	0.77
chr19_13145325_13145476	0.39	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	9589	0.1
chr2_234935375_234935526	0.39	SPP2	secreted phosphoprotein 2, 24kDa	23873	0.21
chr1_110547359_110547543	0.39	AHCYL1	adenosylhomocysteinase-like 1	696	0.64
chr12_123436063_123436316	0.38	ABCB9	ATP-binding cassette, sub-family B (MDR/TAP), member 9	637	0.65
chr1_161053963_161054223	0.38	RP11-544M22.8		162	0.88
chr2_74755282_74756348	0.37	HTRA2	HtrA serine peptidase 2	689	0.35
chr13_114617283_114617434	0.36	GAS6	growth arrest-specific 6	50312	0.16
chr2_16832198_16832526	0.36	FAM49A	family with sequence similarity 49, member A	14734	0.3
chr1_199139099_199139343	0.36	ENSG00000239006	.	27091	0.27
chr10_97033802_97033953	0.36	PDLIM1	PDZ and LIM domain 1	16904	0.21
chr6_52379346_52379497	0.36	TRAM2	translocation associated membrane protein 2	62292	0.12
chr12_90485587_90485738	0.36	ENSG00000252823	.	337826	0.01
chr5_17258824_17258975	0.36	ENSG00000252908	.	18179	0.19
chr4_111012343_111012494	0.35	ENSG00000263940	.	26474	0.22
chr1_39608036_39608283	0.35	ENSG00000222378	.	11809	0.17
chr14_69433021_69433724	0.35	ACTN1	actinin, alpha 1	10911	0.22
chr18_43533746_43533940	0.35	EPG5	ectopic P-granules autophagy protein 5 homolog (C. elegans)	13397	0.21
chr3_124579199_124579350	0.34	ITGB5	integrin, beta 5	11976	0.22
chr3_141459124_141459967	0.34	RNF7	ring finger protein 7	2406	0.32
chr2_106010411_106010562	0.34	FHL2	four and a half LIM domains 2	2756	0.27
chr20_43120698_43120902	0.34	SERINC3	serine incorporator 3	12732	0.12
chr19_15361367_15361598	0.34	EPHX3	epoxide hydrolase 3	17236	0.15
chr10_121438025_121438176	0.34	BAG3	BCL2-associated athanogene 3	21978	0.2
chr11_14334281_14334571	0.34	RRAS2	related RAS viral (r-ras) oncogene homolog 2	17021	0.23
chr3_10975044_10975195	0.34	SLC6A1	solute carrier family 6 (neurotransmitter transporter), member 1	59291	0.13
chr19_47524229_47524951	0.34	NPAS1	neuronal PAS domain protein 1	447	0.8
chr6_45472463_45472958	0.33	RUNX2	runt-related transcription factor 2	82488	0.09
chr12_69895996_69896147	0.33	FRS2	fibroblast growth factor receptor substrate 2	28532	0.18
chr3_23201194_23201345	0.33	UBE2E2-AS1	UBE2E2 antisense RNA 1 (head to head)	42755	0.17
chr1_26604049_26604878	0.33	SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	1204	0.34
chr7_32098298_32098449	0.33	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	12088	0.31
chr9_113507524_113507675	0.33	MUSK	muscle, skeletal, receptor tyrosine kinase	30028	0.23
chr21_30503218_30503405	0.32	MAP3K7CL	MAP3K7 C-terminal like	29	0.97
chr6_150551243_150551394	0.32	ENSG00000238594	.	65598	0.11
chr7_116328446_116328597	0.32	MET	met proto-oncogene	10618	0.25
chr21_44614410_44614785	0.32	CRYAA	crystallin, alpha A	24331	0.16
chr1_16403284_16403435	0.32	FAM131C	family with sequence similarity 131, member C	3238	0.17
chr20_61808362_61808898	0.32	ENSG00000207598	.	1222	0.4
chr11_86304236_86304619	0.32	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial	33565	0.22
chr5_110886683_110887006	0.32	ENSG00000221310	.	4749	0.25
chr12_15791346_15791497	0.32	EPS8	epidermal growth factor receptor pathway substrate 8	23787	0.2
chr15_75952983_75953304	0.31	SNX33	sorting nexin 33	11046	0.09
chr14_69162441_69162592	0.31	CTD-2325P2.3		10234	0.22
chr6_119000629_119000780	0.31	CEP85L	centrosomal protein 85kDa-like	27021	0.25
chr10_75839590_75840110	0.31	VCL	vinculin	3384	0.27
chr1_183247035_183247186	0.31	NMNAT2	nicotinamide nucleotide adenylyltransferase 2	26899	0.22
chr6_33392409_33393194	0.31	SYNGAP1	synaptic Ras GTPase activating protein 1	4769	0.12
chr6_43894795_43895091	0.31	C6orf223	chromosome 6 open reading frame 223	73374	0.08
chr2_183457874_183458025	0.31	PDE1A	phosphodiesterase 1A, calmodulin-dependent	70484	0.12
chr2_54556871_54557022	0.31	C2orf73	chromosome 2 open reading frame 73	225	0.96
chr7_3067277_3067428	0.30	CARD11	caspase recruitment domain family, member 11	16127	0.21
chr1_110599846_110600005	0.30	RP4-773N10.4		1037	0.42
chr16_7104109_7104260	0.30	ENSG00000212189	.	50071	0.19
chr15_39287755_39287906	0.30	RP11-624L4.1		123084	0.06
chr10_62190414_62190565	0.30	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	41001	0.22
chr6_150619137_150619288	0.30	ENSG00000201628	.	28687	0.2
chr1_183578044_183578492	0.30	NCF2	neutrophil cytosolic factor 2	18257	0.16
chr10_34816673_34816973	0.30	PARD3	par-3 family cell polarity regulator	101164	0.08
chr17_56864281_56864432	0.30	PPM1E	protein phosphatase, Mg2+/Mn2+ dependent, 1E	31126	0.14
chr11_108904987_108905286	0.30	ENSG00000201243	.	28892	0.24
chr3_23365897_23366271	0.30	ENSG00000206728	.	50786	0.15
chr5_159975334_159975485	0.30	ENSG00000253522	.	63050	0.09
chr10_30004188_30004339	0.30	ENSG00000222092	.	3419	0.29
chr11_8754629_8754780	0.30	ST5	suppression of tumorigenicity 5	6983	0.14
chr2_133157691_133157842	0.30	ENSG00000252705	.	6665	0.23
chr2_46362187_46362338	0.30	AC017006.3		32855	0.2
chrX_133819704_133819855	0.30	PLAC1	placenta-specific 1	27266	0.17
chr3_30140422_30140573	0.30	ENSG00000264178	.	39242	0.18
chr11_117480962_117481113	0.30	DSCAML1	Down syndrome cell adhesion molecule like 1	186769	0.02
chr6_86171860_86172245	0.29	NT5E	5'-nucleotidase, ecto (CD73)	9047	0.27
chr5_167831746_167831897	0.29	WWC1	WW and C2 domain containing 1	1463	0.51
chr6_155815307_155815458	0.29	NOX3	NADPH oxidase 3	38345	0.21
chr2_74787302_74787609	0.29	LOXL3	lysyl oxidase-like 3	4638	0.1
chr10_120500944_120501242	0.29	CACUL1	CDK2-associated, cullin domain 1	13665	0.23
chr9_115926721_115926872	0.29	SLC31A2	solute carrier family 31 (copper transporter), member 2	13574	0.19
chr18_46015313_46015584	0.29	ENSG00000200872	.	13477	0.23
chr16_85120083_85120456	0.29	KIAA0513	KIAA0513	8244	0.22
chr5_106810991_106811142	0.29	EFNA5	ephrin-A5	195262	0.03
chr4_187766660_187766960	0.29	ENSG00000252382	.	11800	0.3
chr7_134574979_134575413	0.29	CALD1	caldesmon 1	955	0.69
chr6_88517932_88518083	0.29	ENSG00000207131	.	17996	0.18
chr2_42542058_42542320	0.29	EML4	echinoderm microtubule associated protein like 4	13796	0.23
chr7_47812049_47812200	0.28	LINC00525	long intergenic non-protein coding RNA 525	9177	0.21
chr2_144868847_144868998	0.28	GTDC1	glycosyltransferase-like domain containing 1	124382	0.06
chr11_124768065_124768226	0.28	ROBO4	roundabout, axon guidance receptor, homolog 4 (Drosophila)	32	0.96
chr3_149336858_149337009	0.28	WWTR1-IT1	WWTR1 intronic transcript 1 (non-protein coding)	31038	0.15
chr14_76345083_76345346	0.28	RP11-270M14.4		31173	0.2
chr17_905516_905973	0.28	TIMM22	translocase of inner mitochondrial membrane 22 homolog (yeast)	5387	0.15
chr13_76337416_76337595	0.28	LMO7	LIM domain 7	2708	0.37
chr6_49378107_49378258	0.28	MUT	methylmalonyl CoA mutase	52722	0.12
chr13_114616662_114616813	0.28	GAS6	growth arrest-specific 6	49691	0.16
chr10_121440896_121441188	0.28	BAG3	BCL2-associated athanogene 3	24920	0.19
chr4_169032273_169032424	0.28	RP11-310I9.1		2134	0.38
chr11_78356662_78356883	0.28	TENM4	teneurin transmembrane protein 4	56277	0.12
chr3_11739592_11739743	0.28	VGLL4	vestigial like 4 (Drosophila)	12344	0.26
chr7_99349163_99349314	0.28	RP11-757A13.1		14928	0.12
chr3_119180801_119181395	0.28	TMEM39A	transmembrane protein 39A	1365	0.39
chr6_130733603_130733754	0.28	TMEM200A	transmembrane protein 200A	8569	0.22
chr16_30646841_30646992	0.28	PRR14	proline rich 14	15134	0.08
chr6_18047583_18047734	0.28	KIF13A	kinesin family member 13A	59804	0.12
chr10_84741570_84741721	0.28	ENSG00000200774	.	86182	0.11
chr14_34151836_34151987	0.27	NPAS3	neuronal PAS domain protein 3	52536	0.18
chr4_188399877_188400028	0.27	ZFP42	ZFP42 zinc finger protein	516973	0.0
chr3_23306386_23306537	0.27	ENSG00000206728	.	8837	0.25
chr14_100004055_100004358	0.27	CCDC85C	coiled-coil domain containing 85C	1781	0.32
chr1_53914957_53915108	0.27	DMRTB1	DMRT-like family B with proline-rich C-terminal, 1	10040	0.24
chr2_95939319_95939470	0.27	PROM2	prominin 2	807	0.67
chr3_99750954_99751105	0.27	ENSG00000264897	.	67787	0.11
chr7_125342212_125342376	0.27	ENSG00000221418	.	337989	0.01
chr7_107580682_107580917	0.27	CTB-13F3.1		1762	0.37
chr1_22264276_22264522	0.27	HSPG2	heparan sulfate proteoglycan 2	609	0.66
chr13_26594324_26594614	0.27	SHISA2	shisa family member 2	30700	0.19
chr8_38757081_38757383	0.27	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	1521	0.39
chr5_156943457_156943608	0.27	ADAM19	ADAM metallopeptidase domain 19	13702	0.17
chr3_29457012_29457163	0.27	ENSG00000216169	.	46175	0.19
chr12_77452958_77453109	0.27	E2F7	E2F transcription factor 7	6297	0.31
chr20_4141763_4142358	0.27	SMOX	spermine oxidase	10297	0.21
chr10_34927315_34927551	0.27	PARD3	par-3 family cell polarity regulator	176816	0.03
chr3_115718631_115718782	0.27	ENSG00000243359	.	161991	0.04
chr5_97174495_97174646	0.27	CTD-2215E18.2		636986	0.0
chr15_42232481_42232781	0.27	CTD-2382E5.4		19016	0.11
chr8_119081814_119081965	0.27	EXT1	exostosin glycosyltransferase 1	40764	0.22
chr22_30512475_30512626	0.27	HORMAD2	HORMA domain containing 2	35550	0.13
chr1_67856378_67856529	0.27	ENSG00000223263	.	26444	0.17
chr10_124230907_124231058	0.27	HTRA1	HtrA serine peptidase 1	9941	0.19
chr12_835616_835959	0.27	WNK1	WNK lysine deficient protein kinase 1	25972	0.17
chr20_43965620_43965774	0.27	SDC4	syndecan 4	11367	0.11
chr17_76388396_76388760	0.26	ENSG00000200063	.	7438	0.14
chr4_95437074_95437225	0.26	PDLIM5	PDZ and LIM domain 5	7727	0.33
chr10_121426777_121426928	0.26	BAG3	BCL2-associated athanogene 3	10730	0.23
chr22_38172008_38172159	0.26	ENSG00000238569	.	9450	0.11
chr2_18901929_18902080	0.26	NT5C1B	5'-nucleotidase, cytosolic IB	131166	0.05
chr18_59561843_59562473	0.26	RNF152	ring finger protein 152	694	0.82
chr10_33230731_33231366	0.26	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	5869	0.31
chr7_134377764_134377915	0.26	BPGM	2,3-bisphosphoglycerate mutase	32666	0.2
chr9_130299251_130299402	0.26	FAM129B	family with sequence similarity 129, member B	32041	0.13
chr11_130641340_130641491	0.26	C11orf44	chromosome 11 open reading frame 44	98564	0.08
chr15_42237236_42237387	0.26	CTD-2382E5.4		23696	0.1
chr8_97163799_97163950	0.26	GDF6	growth differentiation factor 6	9146	0.25
chr9_3904000_3904151	0.26	GLIS3-AS1	GLIS3 antisense RNA 1	5433	0.28
chr19_46475260_46475748	0.26	NOVA2	neuro-oncological ventral antigen 2	1300	0.34
chr13_102118580_102118731	0.26	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	13637	0.27
chr16_67276341_67276621	0.26	SLC9A5	solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5	4337	0.08
chr6_3841794_3841945	0.26	FAM50B	family with sequence similarity 50, member B	7751	0.21
chr5_14034955_14035229	0.26	DNAH5	dynein, axonemal, heavy chain 5	90440	0.09
chr4_1075635_1075786	0.26	RNF212	ring finger protein 212	31604	0.1
chr7_73720563_73720990	0.26	CLIP2	CAP-GLY domain containing linker protein 2	11101	0.2
chr4_39084466_39084617	0.26	KLHL5	kelch-like family member 5	20394	0.18
chr2_111883522_111883673	0.26	BCL2L11	BCL2-like 11 (apoptosis facilitator)	2268	0.36
chr16_88703444_88703870	0.26	IL17C	interleukin 17C	1344	0.26
chr1_88527460_88527611	0.26	ENSG00000239504	.	416262	0.01
chr18_56247162_56247463	0.26	ENSG00000252284	.	20551	0.14
chr8_121359602_121359753	0.26	COL14A1	collagen, type XIV, alpha 1	1992	0.46
chr14_59203987_59204138	0.26	ENSG00000221427	.	33902	0.22
chr2_153361633_153361784	0.26	FMNL2	formin-like 2	114384	0.07
chr11_94439068_94439219	0.25	AMOTL1	angiomotin like 1	454	0.85
chr15_39506180_39506331	0.25	C15orf54	chromosome 15 open reading frame 54	36630	0.2
chr17_80551323_80552124	0.25	RP13-638C3.3		5436	0.11
chr12_64310525_64310898	0.25	RP11-274J7.2		38144	0.15
chr20_10641236_10641387	0.25	JAG1	jagged 1	1843	0.42
chr8_49228853_49229154	0.25	ENSG00000252710	.	8413	0.32
chr16_68100077_68100483	0.25	ENSG00000221789	.	10493	0.1
chr17_41478549_41478700	0.25	ARL4D	ADP-ribosylation factor-like 4D	2297	0.18
chr2_159317254_159317405	0.25	PKP4	plakophilin 4	3705	0.22
chr11_46671675_46671826	0.25	ATG13	autophagy related 13	9222	0.15
chr11_46293650_46293801	0.25	CTD-2589M5.4		2373	0.27
chr16_53855067_53855218	0.25	FTO	fat mass and obesity associated	65687	0.13
chr1_84842738_84842889	0.25	DNASE2B	deoxyribonuclease II beta	21402	0.19
chr9_37350631_37350782	0.25	ENSG00000206784	.	28450	0.17
chr6_143718929_143719080	0.25	AL031320.1		40571	0.12
chr6_3848448_3848611	0.25	FAM50B	family with sequence similarity 50, member B	1091	0.54
chr6_44032625_44032924	0.25	RP5-1120P11.1		9615	0.18
chr6_12148487_12148638	0.25	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	22583	0.27
chr20_60736205_60736356	0.25	SS18L1	synovial sarcoma translocation gene on chromosome 18-like 1	2436	0.22
chr17_38440826_38440977	0.25	CDC6	cell division cycle 6	2984	0.18
chr16_17604286_17604437	0.25	XYLT1	xylosyltransferase I	39623	0.23
chr4_170100997_170101148	0.25	RP11-327O17.2		21873	0.24
chr2_46538695_46538846	0.25	EPAS1	endothelial PAS domain protein 1	14229	0.26
chr1_86036053_86036204	0.25	DDAH1	dimethylarginine dimethylaminohydrolase 1	7805	0.19
chr7_44419516_44419667	0.25	CAMK2B	calcium/calmodulin-dependent protein kinase II beta	54336	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.2	0.5	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.1	0.4	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.3	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.4	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.4	GO:0070141	response to UV-A(GO:0070141)
0.1	0.4	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.4	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.3	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.3	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.4	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.1	0.2	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	0.3	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.1	1.0	GO:0035329	hippo signaling(GO:0035329)
0.1	0.2	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.3	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.1	0.4	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.1	GO:0032351	regulation of glucocorticoid biosynthetic process(GO:0031946) negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1	0.3	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.3	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.2	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.1	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.3	GO:0043276	anoikis(GO:0043276)
0.1	0.1	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1	0.1	GO:0040023	establishment of nucleus localization(GO:0040023)
0.1	0.4	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.4	GO:0060037	pharyngeal system development(GO:0060037)
0.1	0.2	GO:0045112	integrin biosynthetic process(GO:0045112)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.2	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1	0.2	GO:0060539	diaphragm development(GO:0060539)
0.1	0.2	GO:1904747	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.5	GO:0044065	regulation of respiratory system process(GO:0044065)
0.1	0.2	GO:0061072	iris morphogenesis(GO:0061072)
0.1	0.3	GO:0021873	forebrain neuroblast division(GO:0021873)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.3	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.2	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.1	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.0	GO:0045964	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0061042	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0	0.3	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.2	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.4	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0060841	venous blood vessel development(GO:0060841)
0.0	0.1	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.2	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.3	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.1	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	1.1	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.3	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0060592	mammary gland formation(GO:0060592)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.0	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:1902170	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0045759	negative regulation of action potential(GO:0045759)
0.0	0.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.2	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.0	0.5	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.1	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.3	GO:0009629	response to gravity(GO:0009629)
0.0	0.3	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.2	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.0	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.3	GO:0034644	cellular response to UV(GO:0034644)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0050951	sensory perception of temperature stimulus(GO:0050951) thermoception(GO:0050955)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.2	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.2	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.2	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.2	GO:0006534	cysteine metabolic process(GO:0006534)
0.0	0.1	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.3	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.0	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.1	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0	0.2	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0	0.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.1	GO:0032096	negative regulation of response to food(GO:0032096)
0.0	0.2	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.0	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.3	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.3	GO:0007398	ectoderm development(GO:0007398)
0.0	0.1	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.2	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.5	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.1	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0070528	protein kinase C signaling(GO:0070528)
0.0	0.0	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:1903019	negative regulation of glycoprotein metabolic process(GO:1903019)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.2	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.2	GO:0035510	DNA dealkylation(GO:0035510)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.1	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.0	GO:0060412	ventricular septum morphogenesis(GO:0060412)
0.0	0.1	GO:0071320	cellular response to cAMP(GO:0071320)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.2	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.0	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.0	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.2	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.4	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.3	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.0	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.0	GO:0042117	monocyte activation(GO:0042117)
0.0	0.0	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.1	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.3	GO:0010458	exit from mitosis(GO:0010458)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.4	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.0	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0048385	regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0	0.2	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.2	GO:0006582	melanin metabolic process(GO:0006582)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.2	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.1	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.1	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.0	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0	0.0	GO:0032292	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.9	GO:0051271	negative regulation of cellular component movement(GO:0051271)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.0	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.0	GO:0042519	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.0	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.0	0.3	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	0.1	GO:0002347	response to tumor cell(GO:0002347)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.9	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.0	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0001961	positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.2	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.0	GO:0007442	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.1	GO:0002667	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0010656	negative regulation of muscle cell apoptotic process(GO:0010656)
0.0	0.1	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.0	GO:0061364	regulation of negative chemotaxis(GO:0050923) apoptotic process involved in luteolysis(GO:0061364)
0.0	0.1	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0	0.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.0	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.2	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0071453	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.2	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.1	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0021591	ventricular system development(GO:0021591)
0.0	0.1	GO:2000188	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.0	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0043403	skeletal muscle tissue regeneration(GO:0043403)
0.0	0.0	GO:0006505	GPI anchor metabolic process(GO:0006505)
0.0	0.0	GO:0034969	histone arginine methylation(GO:0034969) histone H4-R3 methylation(GO:0043985)
0.0	0.0	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.1	GO:0006558	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.0	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.0	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.0	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.0	GO:0043474	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.0	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.0	GO:0033089	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.0	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.0	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.0	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0060438	trachea development(GO:0060438)
0.0	0.0	GO:0072033	renal vesicle formation(GO:0072033)
0.0	0.0	GO:1903960	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.0	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0030431	sleep(GO:0030431)
0.0	0.0	GO:0051963	regulation of synapse assembly(GO:0051963)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0071028	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.1	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.2	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.1	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.0	GO:0042160	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.2	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.0	0.0	GO:0070977	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0061515	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0021694	cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.0	GO:0046471	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.5	GO:0006497	protein lipidation(GO:0006497)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.3	GO:0051789	obsolete response to protein(GO:0051789)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.0	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.0	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.1	GO:0015838	amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879)
0.0	0.0	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.0	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	0.1	GO:0000959	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0051310	metaphase plate congression(GO:0051310)
0.0	0.4	GO:0007623	circadian rhythm(GO:0007623)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.0	GO:0046473	phosphatidic acid metabolic process(GO:0046473)
0.0	0.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.0	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.1	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.1	GO:0006693	prostaglandin metabolic process(GO:0006693)
0.0	0.1	GO:0034105	positive regulation of tissue remodeling(GO:0034105)
0.0	0.0	GO:0070295	renal water absorption(GO:0070295)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.0	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.0	0.2	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.0	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0051150	regulation of smooth muscle cell differentiation(GO:0051150)
0.0	0.0	GO:0015853	purine nucleobase transport(GO:0006863) adenine transport(GO:0015853)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0051503	adenine nucleotide transport(GO:0051503)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0032449	CBM complex(GO:0032449)
0.1	0.3	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.3	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.3	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.4	GO:0071437	invadopodium(GO:0071437)
0.1	0.4	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.6	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.6	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.1	0.3	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.2	GO:0043256	laminin complex(GO:0043256)
0.1	0.5	GO:0030127	COPII vesicle coat(GO:0030127)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.1	GO:0070852	cell body fiber(GO:0070852)
0.1	0.3	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.4	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.2	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.4	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.3	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.3	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.9	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.8	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.5	GO:0030057	desmosome(GO:0030057)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.3	GO:0005581	collagen trimer(GO:0005581)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0030870	Mre11 complex(GO:0030870)
0.0	2.0	GO:0005925	focal adhesion(GO:0005925)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.3	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	1.4	GO:0060076	excitatory synapse(GO:0060076)
0.0	0.1	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	1.2	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	1.0	GO:0030496	midbody(GO:0030496)
0.0	0.1	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0002178	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.2	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.0	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	3.6	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	1.1	GO:0045095	keratin filament(GO:0045095)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.0	GO:0071547	piP-body(GO:0071547)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.2	GO:0019861	obsolete flagellum(GO:0019861)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	0.8	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.4	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.9	GO:0017166	vinculin binding(GO:0017166)
0.1	0.3	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.3	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.5	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.3	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.3	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.3	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.1	0.3	GO:0005534	galactose binding(GO:0005534)
0.1	0.2	GO:0045545	syndecan binding(GO:0045545)
0.1	0.2	GO:0046980	tapasin binding(GO:0046980)
0.1	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.2	GO:0048185	activin binding(GO:0048185)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.6	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.2	GO:0043495	protein anchor(GO:0043495)
0.1	1.1	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.2	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.7	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.3	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.2	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.2	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.2	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	1.3	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.4	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.2	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.5	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.2	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.3	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.0	GO:0004675	transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0	0.1	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.4	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.4	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.7	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.0	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.0	GO:0015149	hexose transmembrane transporter activity(GO:0015149)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.5	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.0	GO:0032138	single base insertion or deletion binding(GO:0032138)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.0	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.2	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.3	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.0	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0042923	neuropeptide binding(GO:0042923)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.2	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	1.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.0	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.0	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.0	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.2	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.2	GO:0016411	acylglycerol O-acyltransferase activity(GO:0016411)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.5	GO:0019199	transmembrane receptor protein kinase activity(GO:0019199)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.0	GO:0080031	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.0	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.0	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.1	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.0	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	1.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.1	ST ADRENERGIC	Adrenergic Pathway
0.1	0.6	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	1.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	2.0	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	1.0	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	1.1	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.5	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.4	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.5	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.4	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.4	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	2.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	1.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.1	0.6	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	1.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	2.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.0	REACTOME OPIOID SIGNALLING	Genes involved in Opioid Signalling
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.7	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.1	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.0	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.7	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.6	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	1.2	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.0	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.0	0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.0	REACTOME PERK REGULATED GENE EXPRESSION	Genes involved in PERK regulated gene expression
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.4	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.0	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint

Results for TBX2

Z-value: 1.13

Motif logo

Transcription factors associated with TBX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the TBX2 motif across conditions

Conditions sorted by the z-value of the TBX2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX2

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: