CREMA results: TBX20

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Transcription factors associated with TBX20

Gene Symbol	Gene ID	Gene Info
TBX20 Ensembl NCBI GeneCards UniProt	ENSG00000164532.10	T-box transcription factor 20

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

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CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_35291561_35291712	TBX20	2122	0.437799	0.40	2.9e-01	Click!
chr7_35293101_35293402	TBX20	507	0.870114	0.30	4.3e-01	Click!
chr7_35293912_35294283	TBX20	339	0.929839	0.72	2.7e-02	Click!
chr7_35297544_35297695	TBX20	3861	0.340226	0.37	3.3e-01	Click!
chr7_35420213_35420364	TBX20	126530	0.057190	0.53	1.5e-01	Click!

Showing 1 to 5 of 5 entries

Activity of the TBX20 motif across conditions

Conditions sorted by the z-value of the TBX20 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

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Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_101173362_101173513	0.45	DLK1	delta-like 1 homolog (Drosophila)	18605	0.11
chr12_4353084_4353235	0.44	CCND2	cyclin D2	29779	0.15
chr17_7012818_7013162	0.41	ASGR2	asialoglycoprotein receptor 2	4569	0.12
chr11_118762748_118763140	0.40	RP11-158I9.5		4493	0.11
chr11_1802177_1802346	0.31	CTSD	cathepsin D	17039	0.08
chr8_96228209_96228362	0.31	C8orf37	chromosome 8 open reading frame 37	53144	0.14
chr16_81866339_81866536	0.30	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	50437	0.16
chr18_74086568_74086771	0.30	RP11-504I13.3		1997	0.35
chr5_10644618_10644885	0.29	ANKRD33B-AS1	ANKRD33B antisense RNA 1	16414	0.23
chr18_60917029_60917180	0.27	ENSG00000238988	.	55206	0.11

Showing 1 to 10 of 200 entries

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX20

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.2	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0	0.1	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0007343	egg activation(GO:0007343)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)

Showing 1 to 10 of 33 entries

Gene overrepresentation in cellular component category:

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Total log-likelihood	Term	Description
0.1	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)

Showing 1 to 10 of 10 entries

Gene overrepresentation in molecular function category:

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Total log-likelihood	Term	Description
0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)

Showing 1 to 10 of 19 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Total log-likelihood	Term	Description
0.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway

Showing 1 to 6 of 6 entries

Results for TBX20

Z-value: 0.63

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Transcription factors associated with TBX20

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the TBX20 motif across conditions

Conditions sorted by the z-value of the TBX20 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX20

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: