Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TBX5

Z-value: 1.08

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Transcription factors associated with TBX5

Gene Symbol Gene ID Gene Info
TBX5
ENSG00000089225.15 TBX5

Activity of the TBX5 motif across conditions

Conditions sorted by the z-value of the TBX5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr16_640639_641593 1.40 RAB40C
 RAB40C, member RAS oncogene family
 784
 0.37
chr2_46561339_46561716 0.40 EPAS1
 endothelial PAS domain protein 1
 36986
 0.19
chr12_48148703_48148929 0.37 SLC48A1
 solute carrier family 48 (heme transporter), member 1
 1117
 0.4
chr3_43811469_43811858 0.34 ABHD5
 abhydrolase domain containing 5
 58464
 0.14
chr15_75952983_75953304 0.30 SNX33
 sorting nexin 33
 11046
 0.09
chr5_148833473_148833624 0.29 ENSG00000269936
 .
 23339
 0.13
chr2_109582380_109582745 0.29 EDAR
 ectodysplasin A receptor
 23163
 0.25
chr10_71092552_71092848 0.28 HK1
 hexokinase 1
 14100
 0.18
chr11_93642365_93642516 0.28 VSTM5
 V-set and transmembrane domain containing 5
 58743
 0.09
chr17_38500621_38501691 0.27 RARA
 retinoic acid receptor, alpha
 337
 0.77
chr3_132255311_132255511 0.27 ACKR4
 atypical chemokine receptor 4
 60670
 0.13
chr21_46891130_46891304 0.26 COL18A1
 collagen, type XVIII, alpha 1
 15793
 0.18
chr3_65965340_65965491 0.26 ENSG00000202071
 .
 24200
 0.16
chr10_34927315_34927551 0.26 PARD3
 par-3 family cell polarity regulator
 176816
 0.03
chr4_7051168_7051439 0.26 TADA2B
 transcriptional adaptor 2B
 3248
 0.15
chr8_121668070_121668250 0.26 RP11-713M15.1
105333
 0.07
chr6_86171860_86172245 0.26 NT5E
 5'-nucleotidase, ecto (CD73)
 9047
 0.27
chr15_75944580_75944731 0.26 SNX33
 sorting nexin 33
 2558
 0.14
chr16_29836315_29836998 0.25 MVP
 major vault protein
 4010
 0.08
chr2_109858418_109858699 0.25 ENSG00000265965
 .
 71523
 0.12
chr10_71625915_71626066 0.25 ENSG00000266082
 .
 6935
 0.24
chr7_127260343_127260494 0.25 PAX4
 paired box 4
 4436
 0.17
chr10_4584081_4584405 0.25 ENSG00000207124
 .
 27099
 0.26
chr16_69200425_69200916 0.24 ENSG00000207083
 .
 9010
 0.12
chr7_100803438_100803589 0.24 ENSG00000264425
 .
 759
 0.45
chr2_220334453_220334604 0.24 SPEG
 SPEG complex locus
 8421
 0.1
chr2_235932870_235933072 0.24 SH3BP4
 SH3-domain binding protein 4
 29487
 0.26
chr11_19395379_19395530 0.24 NAV2-IT1
 NAV2 intronic transcript 1 (non-protein coding)
 6577
 0.2
chr8_144351405_144351556 0.24 GLI4
 GLI family zinc finger 4
 48
 0.95
chr5_64493902_64494516 0.23 ENSG00000207439
 .
 75013
 0.12
chr2_65548092_65548243 0.23 SPRED2
 sprouty-related, EVH1 domain containing 2
 13740
 0.24
chr21_46130935_46131086 0.23 TSPEAR
 thrombospondin-type laminin G domain and EAR repeats
 485
 0.67
chr13_76337416_76337595 0.23 LMO7
 LIM domain 7
 2708
 0.37
chr2_220151649_220151800 0.22 ENSG00000207647
 .
 7198
 0.08
chr20_30085655_30085806 0.22 HM13
 histocompatibility (minor) 13
 16501
 0.11
chr3_123033355_123033506 0.22 RP11-797D24.4
30990
 0.21
chr19_11253483_11254153 0.22 SPC24
 SPC24, NDC80 kinetochore complex component
 12619
 0.13
chr11_2411400_2411766 0.22 CD81
 CD81 molecule
 258
 0.86
chr22_46502171_46502327 0.22 ENSG00000198986
 .
 6380
 0.1
chr1_209492590_209492741 0.22 ENSG00000230937
 .
 112813
 0.07
chr10_3134024_3134295 0.22 PFKP
 phosphofructokinase, platelet
 12757
 0.24
chr12_77452958_77453109 0.22 E2F7
 E2F transcription factor 7
 6297
 0.31
chr6_150018396_150018597 0.22 LATS1
 large tumor suppressor kinase 1
 4994
 0.17
chr1_223925166_223925317 0.21 CAPN2
 calpain 2, (m/II) large subunit
 25207
 0.19
chr8_1708170_1708321 0.21 CTD-2336O2.1
3218
 0.25
chr14_69433021_69433724 0.21 ACTN1
 actinin, alpha 1
 10911
 0.22
chr1_225648223_225648895 0.21 RP11-496N12.6
4426
 0.24
chr20_46294424_46294575 0.21 SULF2
 sulfatase 2
 496
 0.82
chr2_174856949_174857100 0.21 SP3
 Sp3 transcription factor
 26594
 0.26
chr1_145652701_145652852 0.21 RNF115
 ring finger protein 115
 41740
 0.09
chr17_41142970_41143188 0.21 ENSG00000200127
 .
 6945
 0.07
chr12_49934382_49934533 0.21 KCNH3
 potassium voltage-gated channel, subfamily H (eag-related), member 3
 1517
 0.31
chr11_62380716_62381015 0.21 ROM1
 retinal outer segment membrane protein 1
 136
 0.81
chr20_33168242_33168500 0.21 MAP1LC3A
 microtubule-associated protein 1 light chain 3 alpha
 21849
 0.16
chr1_16277969_16279055 0.20 ZBTB17
 zinc finger and BTB domain containing 17
 7589
 0.15
chr10_34987624_34987775 0.20 PARD3
 par-3 family cell polarity regulator
 116550
 0.06
chr14_105439124_105439578 0.20 AHNAK2
 AHNAK nucleoprotein 2
 5343
 0.17
chr17_5026950_5027101 0.20 ZNF232
 zinc finger protein 232
 628
 0.57
chr2_74159231_74159740 0.20 DGUOK
 deoxyguanosine kinase
 5450
 0.18
chr18_42835925_42836076 0.20 SLC14A2
 solute carrier family 14 (urea transporter), member 2
 43040
 0.18
chr14_99656353_99656504 0.20 AL162151.4
31675
 0.2
chr16_19707530_19708296 0.20 C16orf62
 chromosome 16 open reading frame 62
 5135
 0.16
chr1_21669331_21669865 0.20 ECE1
 endothelin converting enzyme 1
 2399
 0.33
chr19_10119280_10119522 0.20 COL5A3
 collagen, type V, alpha 3
 1746
 0.21
chr2_37811630_37811924 0.20 AC006369.2
15502
 0.25
chr15_89189808_89189959 0.20 ISG20
 interferon stimulated exonuclease gene 20kDa
 7699
 0.17
chr11_86304236_86304619 0.20 ME3
 malic enzyme 3, NADP(+)-dependent, mitochondrial
 33565
 0.22
chr19_19448791_19448942 0.20 MAU2
 MAU2 sister chromatid cohesion factor
 851
 0.51
chr7_73995059_73995210 0.20 ENSG00000252378
 .
 9457
 0.21
chr2_234935375_234935526 0.20 SPP2
 secreted phosphoprotein 2, 24kDa
 23873
 0.21
chr2_10637857_10638008 0.20 ODC1
 ornithine decarboxylase 1
 49302
 0.12
chr19_30186180_30186331 0.19 C19orf12
 chromosome 19 open reading frame 12
 13292
 0.22
chr9_131397478_131397629 0.19 WDR34
 WD repeat domain 34
 21407
 0.11
chr21_44465729_44466640 0.19 CBS
 cystathionine-beta-synthase
 12867
 0.18
chr8_49228853_49229154 0.19 ENSG00000252710
 .
 8413
 0.32
chr9_89764391_89764542 0.19 C9orf170
 chromosome 9 open reading frame 170
 907
 0.73
chr11_46716050_46716224 0.19 ARHGAP1
 Rho GTPase activating protein 1
 1512
 0.29
chr9_99738397_99738548 0.19 HIATL2
 hippocampus abundant transcript-like 2
 37390
 0.16
chr9_117567236_117567387 0.19 TNFSF15
 tumor necrosis factor (ligand) superfamily, member 15
 1095
 0.57
chr20_45964041_45964253 0.19 ZMYND8
 zinc finger, MYND-type containing 8
 12669
 0.12
chr15_48042955_48043106 0.19 SEMA6D
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
 8890
 0.3
chr8_119024491_119024642 0.19 EXT1
 exostosin glycosyltransferase 1
 98087
 0.09
chr13_111100125_111100276 0.19 COL4A2-AS2
 COL4A2 antisense RNA 2
 15434
 0.2
chr1_92341726_92342008 0.19 TGFBR3
 transforming growth factor, beta receptor III
 9799
 0.22
chr6_144780980_144781131 0.19 UTRN
 utrophin
 115818
 0.07
chr12_680340_680491 0.19 RP5-1154L15.2
15237
 0.13
chr2_43383016_43383167 0.19 ENSG00000207087
 .
 64459
 0.12
chr15_83957241_83957392 0.19 BNC1
 basonuclin 1
 3850
 0.29
chr17_37030037_37031006 0.18 LASP1
 LIM and SH3 protein 1
 378
 0.73
chr1_45982973_45983124 0.18 PRDX1
 peroxiredoxin 1
 4478
 0.15
chr17_19249457_19249608 0.18 ENSG00000221540
 .
 1645
 0.23
chr17_79787756_79787907 0.18 FAM195B
 family with sequence similarity 195, member B
 3287
 0.09
chr14_96721657_96721808 0.18 BDKRB1
 bradykinin receptor B1
 429
 0.75
chr2_120996591_120996972 0.18 RALB
 v-ral simian leukemia viral oncogene homolog B
 859
 0.59
chr3_45532536_45532687 0.18 LARS2-AS1
 LARS2 antisense RNA 1
 18426
 0.22
chr5_159301342_159301493 0.18 ADRA1B
 adrenoceptor alpha 1B
 42373
 0.19
chr12_103889778_103890152 0.18 C12orf42
 chromosome 12 open reading frame 42
 216
 0.96
chr19_2529730_2529881 0.18 ENSG00000252962
 .
 26666
 0.13
chr22_18539696_18539847 0.18 XXbac-B476C20.9
20792
 0.13
chr4_13919303_13919486 0.18 ENSG00000252092
 .
 259143
 0.02
chr9_21611252_21611476 0.18 MIR31HG
 MIR31 host gene (non-protein coding)
 51696
 0.12
chr16_31438497_31438648 0.18 COX6A2
 cytochrome c oxidase subunit VIa polypeptide 2
 1177
 0.3
chr2_235589189_235589340 0.18 ARL4C
 ADP-ribosylation factor-like 4C
 183567
 0.03
chr3_101545279_101545565 0.18 NFKBIZ
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
 1413
 0.33
chr1_9779729_9779880 0.18 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 1677
 0.35
chr6_42282569_42282720 0.18 MRPS10
 mitochondrial ribosomal protein S10
 97041
 0.06
chr6_155272636_155272949 0.18 TIAM2
 T-cell lymphoma invasion and metastasis 2
 43696
 0.14
chr3_149212274_149212425 0.18 TM4SF4
 transmembrane 4 L six family member 4
 19863
 0.18
chr21_44144056_44144280 0.18 AP001627.1
17700
 0.2
chr22_18402631_18402902 0.18 MICAL3
 microtubule associated monooxygenase, calponin and LIM domain containing 3
 13126
 0.2
chr6_43404132_43404283 0.18 ABCC10
 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
 4718
 0.14
chr2_227312371_227312522 0.18 ENSG00000263363
 .
 211063
 0.02
chr8_124550936_124551167 0.18 FBXO32
 F-box protein 32
 2395
 0.31
chr3_11739592_11739743 0.18 VGLL4
 vestigial like 4 (Drosophila)
 12344
 0.26
chr1_2216519_2216670 0.18 RP4-713A8.1
41538
 0.09
chr3_52083231_52083382 0.18 DUSP7
 dual specificity phosphatase 7
 6875
 0.12
chr9_102828132_102828283 0.17 ERP44
 endoplasmic reticulum protein 44
 33115
 0.15
chr19_4372661_4373353 0.17 SH3GL1
 SH3-domain GRB2-like 1
 7282
 0.08
chr20_33409196_33409347 0.17 NCOA6
 nuclear receptor coactivator 6
 171
 0.95
chr3_149291004_149291431 0.17 WWTR1
 WW domain containing transcription regulator 1
 2822
 0.29
chr14_77769480_77769631 0.17 POMT2
 protein-O-mannosyltransferase 2
 17128
 0.12
chr2_114086968_114087119 0.17 PAX8
 paired box 8
 50516
 0.11
chr1_95484423_95484574 0.17 RP11-313A24.1
42654
 0.12
chr22_32025367_32025527 0.17 PISD
 phosphatidylserine decarboxylase
 479
 0.82
chr3_118924482_118924633 0.17 UPK1B
 uroplakin 1B
 18972
 0.13
chr20_62541412_62541595 0.17 ENSG00000199805
 .
 1195
 0.23
chr2_220510107_220510260 0.17 SLC4A3
 solute carrier family 4 (anion exchanger), member 3
 14331
 0.12
chr1_94521327_94521478 0.17 ABCA4
 ATP-binding cassette, sub-family A (ABC1), member 4
 37174
 0.17
chr22_36863560_36864238 0.17 TXN2
 thioredoxin 2
 13488
 0.14
chr11_72951179_72951330 0.17 RP11-800A3.4
1234
 0.39
chr14_99677205_99677461 0.17 AL109767.1
51952
 0.13
chr11_12200417_12200568 0.17 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 16789
 0.24
chr12_69895996_69896147 0.17 FRS2
 fibroblast growth factor receptor substrate 2
 28532
 0.18
chr2_47496531_47496728 0.17 EPCAM
 epithelial cell adhesion molecule
 75668
 0.08
chr13_110975398_110975549 0.17 COL4A2
 collagen, type IV, alpha 2
 15859
 0.21
chr3_141459124_141459967 0.17 RNF7
 ring finger protein 7
 2406
 0.32
chr5_56833824_56833975 0.17 ACTBL2
 actin, beta-like 2
 55263
 0.14
chr1_120529562_120529713 0.17 NOTCH2
 notch 2
 67202
 0.11
chr17_8368348_8368499 0.17 NDEL1
 nudE neurodevelopment protein 1-like 1
 14324
 0.14
chr17_75472485_75473009 0.17 SEPT9
 septin 9
 1422
 0.36
chr9_132948947_132949098 0.17 NCS1
 neuronal calcium sensor 1
 13850
 0.2
chr20_42831632_42831792 0.17 OSER1
 oxidative stress responsive serine-rich 1
 7004
 0.18
chr13_99661699_99661850 0.17 DOCK9
 dedicator of cytokinesis 9
 6199
 0.23
chr9_72580621_72580772 0.17 MAMDC2
 MAM domain containing 2
 77801
 0.09
chr17_79069087_79069486 0.16 BAIAP2
 BAI1-associated protein 2
 2093
 0.2
chr4_26223553_26223704 0.16 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 50601
 0.19
chr7_44298814_44299210 0.16 CAMK2B
 calcium/calmodulin-dependent protein kinase II beta
 17107
 0.18
chr2_106010411_106010562 0.16 FHL2
 four and a half LIM domains 2
 2756
 0.27
chr12_7033713_7034270 0.16 ATN1
 atrophin 1
 365
 0.64
chr19_47454045_47454267 0.16 ENSG00000252071
 .
 2610
 0.26
chr11_1627611_1627762 0.16 KRTAP5-3
 keratin associated protein 5-3
 2007
 0.19
chr11_7545965_7546116 0.16 PPFIBP2
 PTPRF interacting protein, binding protein 2 (liprin beta 2)
 11039
 0.17
chr20_42091056_42091207 0.16 SRSF6
 serine/arginine-rich splicing factor 6
 4563
 0.17
chr9_132394305_132394475 0.16 NTMT1
 N-terminal Xaa-Pro-Lys N-methyltransferase 1
 5667
 0.13
chr2_219510257_219510408 0.16 PLCD4
 phospholipase C, delta 4
 9754
 0.09
chr9_97665628_97665779 0.16 RP11-49O14.2
2992
 0.26
chr20_45754813_45755050 0.16 ENSG00000264901
 .
 40678
 0.18
chr11_1848080_1848428 0.16 SYT8
 synaptotagmin VIII
 455
 0.69
chr5_66456204_66456364 0.16 MAST4
 microtubule associated serine/threonine kinase family member 4
 18022
 0.24
chr14_69526384_69526535 0.16 ACTN1-AS1
 ACTN1 antisense RNA 1
 79701
 0.08
chr1_15733231_15733382 0.16 EFHD2
 EF-hand domain family, member D2
 3085
 0.2
chr14_69413225_69413821 0.16 ACTN1
 actinin, alpha 1
 742
 0.72
chr8_17474809_17474960 0.16 PDGFRL
 platelet-derived growth factor receptor-like
 40183
 0.14
chr1_53914957_53915108 0.16 DMRTB1
 DMRT-like family B with proline-rich C-terminal, 1
 10040
 0.24
chr2_54556871_54557022 0.16 C2orf73
 chromosome 2 open reading frame 73
 225
 0.96
chr3_57633336_57633487 0.16 DENND6A
 DENN/MADD domain containing 6A
 13142
 0.13
chr5_71160967_71161118 0.16 CARTPT
 CART prepropeptide
 146052
 0.04
chr10_29936930_29937596 0.16 SVIL
 supervillin
 13362
 0.21
chr6_112300641_112300792 0.16 WISP3
 WNT1 inducible signaling pathway protein 3
 74559
 0.1
chr1_85962794_85962945 0.16 DDAH1
 dimethylarginine dimethylaminohydrolase 1
 32042
 0.18
chr2_46362187_46362338 0.16 AC017006.3
32855
 0.2
chr22_38597727_38597878 0.16 MAFF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
 87
 0.95
chr22_46487121_46487272 0.16 ENSG00000266533
 .
 272
 0.83
chr16_88745700_88745936 0.16 SNAI3-AS1
 SNAI3 antisense RNA 1
 5723
 0.08
chr13_45390060_45390211 0.16 NUFIP1
 nuclear fragile X mental retardation protein interacting protein 1
 173483
 0.03
chr14_100004055_100004358 0.16 CCDC85C
 coiled-coil domain containing 85C
 1781
 0.32
chr20_43120698_43120902 0.16 SERINC3
 serine incorporator 3
 12732
 0.12
chr7_511187_511386 0.16 PDGFA
 platelet-derived growth factor alpha polypeptide
 46859
 0.15
chr15_83379220_83379371 0.16 AP3B2
 adaptor-related protein complex 3, beta 2 subunit
 629
 0.62
chr22_25346242_25346393 0.16 KIAA1671
 KIAA1671
 2380
 0.29
chr2_28886936_28887087 0.16 AC074011.2
395
 0.85
chr17_79037916_79038067 0.16 BAIAP2
 BAI1-associated protein 2
 6457
 0.14
chr5_73933431_73933582 0.16 HEXB
 hexosaminidase B (beta polypeptide)
 2342
 0.29
chr19_57793685_57794097 0.16 ZNF460
 zinc finger protein 460
 636
 0.55
chr17_44811165_44811316 0.16 NSF
 N-ethylmaleimide-sensitive factor
 7318
 0.24
chr1_181002368_181002929 0.16 MR1
 major histocompatibility complex, class I-related
 419
 0.83
chr11_63888926_63889077 0.16 RP11-21A7A.3
2319
 0.18
chr3_189873636_189873787 0.16 ENSG00000212489
 .
 9601
 0.16
chr6_56598121_56598272 0.16 DST
 dystonin
 52481
 0.16
chr10_71101466_71101659 0.15 ENSG00000221774
 .
 21835
 0.16
chr6_14673745_14673896 0.15 ENSG00000206960
 .
 27054
 0.27
chr9_37350631_37350782 0.15 ENSG00000206784
 .
 28450
 0.17
chr8_101473999_101474150 0.15 KB-1615E4.2
13829
 0.18
chr2_99118492_99118714 0.15 INPP4A
 inositol polyphosphate-4-phosphatase, type I, 107kDa
 17909
 0.23
chr8_20164020_20164171 0.15 LZTS1
 leucine zipper, putative tumor suppressor 1
 2621
 0.31
chr9_113698106_113698257 0.15 ENSG00000207401
 .
 1495
 0.47
chr11_67078909_67079060 0.15 SSH3
 slingshot protein phosphatase 3
 3856
 0.13
chr1_23158206_23158357 0.15 RP11-69E9.1
5061
 0.21
chr15_74217253_74217502 0.15 LOXL1-AS1
 LOXL1 antisense RNA 1
 1262
 0.31
chr1_23016118_23016418 0.15 EPHB2
 EPH receptor B2
 21064
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of TBX5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 0.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.2 GO:1902170 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.1 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.2 GO:1903521 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 0.2 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1 0.4 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.1 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.2 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.1 GO:0060068 vagina development(GO:0060068)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.2 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.2 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.0 GO:0055026 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.2 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.0 0.1 GO:0034776 response to histamine(GO:0034776)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0090081 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0003211 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.1 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.2 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0 0.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0061042 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0 0.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.0 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.1 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 0.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.1 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.0 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.0 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.3 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.3 GO:0038061 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0010659 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:1903019 negative regulation of glycoprotein metabolic process(GO:1903019)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.0 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.2 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.2 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.0 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0032324 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.0 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.0 GO:0002677 negative regulation of chronic inflammatory response(GO:0002677)
0.0 0.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.0 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.0 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.0 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0042268 regulation of cytolysis(GO:0042268)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.0 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0032096 negative regulation of response to food(GO:0032096)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.0 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.0 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.3 GO:0007045 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.0 GO:0060346 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0 0.0 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.2 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) auditory receptor cell fate determination(GO:0042668) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.0 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0046902 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0051594 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.0 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 0.1 GO:2000738 positive regulation of stem cell differentiation(GO:2000738)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.0 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.0 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.0 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0048242 epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 0.0 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.0 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.0 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.0 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.0 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.0 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.0 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.0 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.0 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.0 0.0 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0090493 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.0 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0007566 embryo implantation(GO:0007566)
0.0 0.0 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.0 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.1 GO:0032817 regulation of natural killer cell proliferation(GO:0032817)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0072498 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0 0.0 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.0 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.0 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.0 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.0 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.2 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.0 GO:0035269 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.0 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.0 GO:0003254 regulation of membrane depolarization(GO:0003254) regulation of mitochondrial depolarization(GO:0051900)
0.0 0.0 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.0 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.0 0.0 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0055094 response to lipoprotein particle(GO:0055094)
0.0 0.0 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0033643 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.0 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.0 GO:0043230 extracellular organelle(GO:0043230)
0.0 0.3 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.0 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.0 GO:0043218 compact myelin(GO:0043218)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.6 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.2 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.0 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.0 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.0 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.0 GO:0034711 inhibin binding(GO:0034711)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.0 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.0 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0019798 procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 ST ADRENERGIC Adrenergic Pathway
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.0 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.0 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.0 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.1 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.3 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.0 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination