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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for TCF12_ASCL2

Z-value: 1.45

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Transcription factors associated with TCF12_ASCL2

Gene Symbol	Gene ID	Gene Info
TCF12 Ensembl NCBI GeneCards UniProt	ENSG00000140262.13	transcription factor 12
ASCL2 Ensembl NCBI GeneCards UniProt	ENSG00000183734.4	achaete-scute family bHLH transcription factor 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_2290591_2290742	ASCL2	1516	0.311441	-0.39	3.0e-01	Click!
chr11_2292636_2292787	ASCL2	529	0.707417	0.22	5.7e-01	Click!
chr11_2291133_2291433	ASCL2	899	0.495979	0.22	5.8e-01	Click!
chr11_2291942_2292148	ASCL2	137	0.943823	-0.17	6.6e-01	Click!
chr11_2289576_2289727	ASCL2	2531	0.208153	-0.17	6.6e-01	Click!
chr15_57614116_57614267	TCF12	39538	0.151673	0.77	1.5e-02	Click!
chr15_57220669_57220820	TCF12	9398	0.212245	-0.77	1.5e-02	Click!
chr15_57537305_57537456	TCF12	2834	0.337093	0.77	1.6e-02	Click!
chr15_57233897_57234181	TCF12	22693	0.181818	-0.75	2.0e-02	Click!
chr15_57521161_57521312	TCF12	9572	0.263652	0.74	2.3e-02	Click!

Activity of the TCF12_ASCL2 motif across conditions

Conditions sorted by the z-value of the TCF12_ASCL2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_159107_159571	1.14	ENSG00000199540	.	15027	0.14
chr7_155387096_155387344	0.80	AC009403.2	Protein LOC100506302	49875	0.12
chr15_94408923_94409174	0.68	ENSG00000222409	.	31208	0.26
chr9_97567295_97567893	0.65	ENSG00000252153	.	4650	0.2
chr11_63638814_63639520	0.63	MARK2	MAP/microtubule affinity-regulating kinase 2	2419	0.21
chr7_17812443_17812892	0.63	SNX13	sorting nexin 13	167424	0.04
chr1_212844814_212845399	0.58	ENSG00000207491	.	20500	0.14
chr1_201562896_201563143	0.56	AC096677.1	Uncharacterized protein ENSP00000471857	28994	0.14
chr9_21119427_21119782	0.53	IFNW1	interferon, omega 1	22540	0.12
chr10_101604205_101604725	0.53	DNMBP	dynamin binding protein	53554	0.11
chr8_103802696_103803356	0.47	ENSG00000266799	.	57079	0.11
chr11_67838704_67838889	0.45	RP11-802E16.3		18506	0.11
chr2_85777153_85777517	0.45	MAT2A	methionine adenosyltransferase II, alpha	10570	0.09
chr17_81008765_81009012	0.45	B3GNTL1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1	798	0.68
chr8_49341467_49342503	0.44	ENSG00000252710	.	121395	0.06
chr7_47641377_47641730	0.43	TNS3	tensin 3	19397	0.24
chr3_45595189_45595741	0.43	ENSG00000251927	.	38282	0.14
chr6_14884243_14884494	0.42	ENSG00000242989	.	228831	0.02
chr17_76880562_76881090	0.42	TIMP2	TIMP metallopeptidase inhibitor 2	10594	0.14
chr2_55347968_55348289	0.42	RTN4	reticulon 4	8371	0.19
chr20_30743365_30743658	0.41	ENSG00000265736	.	36957	0.11
chr18_60118168_60118548	0.41	ZCCHC2	zinc finger, CCHC domain containing 2	71882	0.1
chr6_109561464_109561868	0.40	ENSG00000238474	.	50895	0.12
chr10_126835454_126835747	0.40	CTBP2	C-terminal binding protein 2	11685	0.28
chr22_36828593_36829238	0.39	ENSG00000252575	.	6056	0.16
chr1_44249233_44249560	0.39	ST3GAL3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	47462	0.11
chr4_185779878_185780042	0.38	ENSG00000266698	.	7696	0.2
chr4_6877165_6877316	0.38	TBC1D14	TBC1 domain family, member 14	33729	0.15
chr15_74277606_74277925	0.38	STOML1	stomatin (EPB72)-like 1	6410	0.16
chr3_49842732_49843503	0.37	ENSG00000263506	.	561	0.55
chr10_35776302_35776593	0.37	GJD4	gap junction protein, delta 4, 40.1kDa	117891	0.05
chr19_17221488_17221977	0.37	MYO9B	myosin IXB	9204	0.12
chr6_6714421_6714707	0.37	LY86-AS1	LY86 antisense RNA 1	91560	0.09
chr22_19650921_19651247	0.37	SEPT5	septin 5	50903	0.11
chr17_9160012_9160446	0.36	RP11-85B7.4		26262	0.21
chr8_134249943_134250266	0.36	WISP1-OT1	WISP1 overlapping transcript 1 (non-protein coding)	8805	0.23
chr6_12963445_12963682	0.35	PHACTR1	phosphatase and actin regulator 1	5349	0.34
chr8_98002610_98002912	0.35	CPQ	carboxypeptidase Q	38936	0.21
chr19_3951431_3951582	0.35	DAPK3	death-associated protein kinase 3	9651	0.1
chr20_17627676_17628109	0.35	RRBP1	ribosome binding protein 1	13260	0.2
chr8_56860789_56861156	0.35	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	8179	0.16
chr9_127049180_127049370	0.34	NEK6	NIMA-related kinase 6	556	0.76
chr8_10486578_10486974	0.34	RP1L1	retinitis pigmentosa 1-like 1	25836	0.14
chr11_73024899_73025487	0.34	ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17	2583	0.2
chr15_91458563_91458756	0.34	MAN2A2	mannosidase, alpha, class 2A, member 2	2541	0.13
chr2_55339476_55339889	0.34	RTN4	reticulon 4	75	0.97
chr15_58524513_58524782	0.33	ALDH1A2	aldehyde dehydrogenase 1 family, member A2	46815	0.17
chr15_59823301_59823617	0.33	ENSG00000201704	.	42962	0.12
chr12_52585492_52585885	0.33	KRT80	keratin 80	96	0.95
chr17_79423279_79423430	0.32	ENSG00000266189	.	5140	0.12
chr17_61477281_61477632	0.32	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2	4352	0.16
chr3_48597793_48598316	0.32	PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	508	0.63
chr6_90021967_90022444	0.32	GABRR2	gamma-aminobutyric acid (GABA) A receptor, rho 2	2762	0.29
chr14_69388884_69389440	0.32	ACTN1	actinin, alpha 1	25103	0.2
chr17_19912897_19913158	0.32	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1	149	0.82
chr3_123337794_123338198	0.32	MYLK	myosin light chain kinase	1365	0.44
chr17_42849030_42849346	0.31	ADAM11	ADAM metallopeptidase domain 11	12495	0.13
chr14_75787133_75787431	0.31	FOS	FBJ murine osteosarcoma viral oncogene homolog	40386	0.13
chr20_23008934_23009272	0.31	RP4-753D10.5		2319	0.23
chr13_30071250_30071401	0.31	MTUS2-AS1	MTUS2 antisense RNA 1	7083	0.28
chr6_43083911_43084141	0.31	PTK7	protein tyrosine kinase 7	14303	0.11
chr2_60713197_60713392	0.31	AC009970.1		9527	0.25
chrX_53350130_53350441	0.31	IQSEC2	IQ motif and Sec7 domain 2	237	0.92
chr9_90215657_90216062	0.31	DAPK1-IT1	DAPK1 intronic transcript 1 (non-protein coding)	47490	0.16
chr3_156423893_156424045	0.31	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase	25014	0.2
chr1_230279012_230279387	0.30	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	76181	0.1
chr17_25886952_25887281	0.30	KSR1	kinase suppressor of ras 1	22831	0.19
chr2_237657369_237658039	0.30	ACKR3	atypical chemokine receptor 3	179420	0.03
chr20_47449148_47449557	0.30	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	4932	0.3
chr15_90608689_90609006	0.30	ZNF710	zinc finger protein 710	2399	0.22
chr7_6474034_6474265	0.30	DAGLB	diacylglycerol lipase, beta	13414	0.16
chr1_204940620_204940796	0.30	NFASC	neurofascin	10276	0.21
chr20_49306472_49306623	0.30	FAM65C	family with sequence similarity 65, member C	1369	0.41
chr16_87850340_87850491	0.30	RP4-536B24.2		19723	0.16
chr3_128566375_128566773	0.30	RP11-723O4.2		17873	0.16
chr16_88989864_88990015	0.30	RP11-830F9.7		14225	0.11
chr14_105860468_105860995	0.30	PACS2	phosphofurin acidic cluster sorting protein 2	2935	0.17
chr16_72971482_72971633	0.29	ENSG00000221799	.	47199	0.14
chr1_150971890_150972106	0.29	FAM63A	family with sequence similarity 63, member A	1352	0.23
chr1_94018769_94019015	0.29	FNBP1L	formin binding protein 1-like	23625	0.16
chr16_81466769_81467025	0.29	CMIP	c-Maf inducing protein	11878	0.23
chrX_12991572_12991862	0.29	TMSB4X	thymosin beta 4, X-linked	1510	0.46
chr9_116419577_116419869	0.29	RGS3	regulator of G-protein signaling 3	63957	0.12
chr3_74090598_74090749	0.29	ENSG00000212585	.	124530	0.06
chr22_24734329_24734480	0.29	SPECC1L	sperm antigen with calponin homology and coiled-coil domains 1-like	34040	0.15
chr17_40670908_40671198	0.29	ENSG00000265611	.	4847	0.09
chr9_111483068_111483236	0.29	ACTL7B	actin-like 7B	136087	0.05
chr2_174889480_174890119	0.29	SP3	Sp3 transcription factor	59369	0.15
chr16_85569403_85569588	0.28	GSE1	Gse1 coiled-coil protein	75520	0.09
chr9_16885120_16885444	0.28	BNC2	basonuclin 2	14441	0.29
chr12_8043408_8043946	0.28	SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14	67	0.95
chr2_27110278_27110603	0.28	DPYSL5	dihydropyrimidinase-like 5	39064	0.12
chr22_46404101_46404436	0.28	WNT7B	wingless-type MMTV integration site family, member 7B	31259	0.1
chr1_6803545_6803777	0.28	ENSG00000239166	.	9118	0.17
chr17_38495361_38495755	0.28	RARA	retinoic acid receptor, alpha	2082	0.19
chr1_235092841_235093046	0.28	ENSG00000239690	.	53010	0.15
chr16_66262660_66262838	0.28	ENSG00000201999	.	72963	0.11
chr21_39792072_39792223	0.28	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog	78198	0.11
chr5_149867249_149867416	0.28	NDST1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	1475	0.4
chr12_117549775_117550128	0.28	TESC	tescalcin	12677	0.25
chr4_185819623_185819887	0.28	ENSG00000263458	.	39839	0.14
chr16_88058565_88058905	0.28	BANP	BTG3 associated nuclear protein	55111	0.14
chr9_37995152_37995751	0.27	ENSG00000251745	.	58686	0.12
chr21_44994556_44994959	0.27	HSF2BP	heat shock transcription factor 2 binding protein	83268	0.08
chr1_68023561_68023948	0.27	ENSG00000207504	.	16944	0.24
chr3_45687605_45688015	0.27	LIMD1-AS1	LIMD1 antisense RNA 1	42564	0.12
chr5_10626171_10626466	0.27	ANKRD33B-AS1	ANKRD33B antisense RNA 1	2019	0.39
chr8_38815176_38815498	0.27	CTD-2544N14.3		15193	0.14
chr10_112440356_112440650	0.27	RBM20	RNA binding motif protein 20	36348	0.12
chr2_38046333_38046643	0.27	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	80877	0.1
chr6_106957352_106957633	0.27	AIM1	absent in melanoma 1	2238	0.32
chr20_62273575_62273807	0.27	STMN3	stathmin-like 3	10428	0.1
chr13_114271779_114271980	0.27	TFDP1	transcription factor Dp-1	32138	0.15
chr3_155382068_155382258	0.27	PLCH1	phospholipase C, eta 1	11665	0.26
chr19_54851250_54851616	0.27	LILRA4	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4	1012	0.36
chr3_38153140_38153365	0.27	ENSG00000201965	.	13633	0.14
chr16_81867475_81867678	0.27	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	49298	0.17
chr11_44986217_44986403	0.27	TP53I11	tumor protein p53 inducible protein 11	13702	0.26
chr16_29329349_29329588	0.27	RP11-231C14.6		5797	0.19
chr1_54686195_54686878	0.26	MRPL37	mitochondrial ribosomal protein L37	10917	0.13
chr5_124071161_124071462	0.26	RP11-436H11.5		443	0.7
chr6_18215332_18215496	0.26	KDM1B	lysine (K)-specific demethylase 1B	29395	0.15
chrX_19893812_19894177	0.26	SH3KBP1	SH3-domain kinase binding protein 1	11583	0.26
chr19_47226569_47226765	0.26	STRN4	striatin, calmodulin binding protein 4	199	0.87
chr4_57737830_57738076	0.26	REST	RE1-silencing transcription factor	36122	0.13
chr11_72896529_72896905	0.26	RP11-800A3.2		30241	0.13
chr3_10056900_10057167	0.26	EMC3	ER membrane protein complex subunit 3	4233	0.11
chr14_62056982_62057488	0.26	RP11-47I22.3	Uncharacterized protein	19921	0.2
chr1_94558563_94558714	0.26	ABCA4	ATP-binding cassette, sub-family A (ABC1), member 4	28043	0.17
chr9_124273187_124273484	0.26	ENSG00000240299	.	16538	0.18
chr15_75125162_75125365	0.26	CPLX3	complexin 3	6375	0.11
chr1_87258504_87258666	0.26	SH3GLB1	SH3-domain GRB2-like endophilin B1	88007	0.07
chr3_185813558_185813840	0.26	ETV5	ets variant 5	12634	0.21
chr13_46957483_46957881	0.26	KIAA0226L	KIAA0226-like	3635	0.23
chr19_51964659_51964879	0.26	SIGLEC8	sialic acid binding Ig-like lectin 8	3059	0.13
chr2_234257865_234258016	0.26	RP11-400N9.1		4122	0.17
chr13_81205127_81205302	0.26	ENSG00000202398	.	261545	0.02
chr15_70779488_70780159	0.26	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	214797	0.02
chr1_172792534_172792808	0.26	FASLG	Fas ligand (TNF superfamily, member 6)	164513	0.04
chr20_31252924_31253424	0.26	RP11-410N8.4		63735	0.09
chr19_18283405_18283975	0.26	IFI30	interferon, gamma-inducible protein 30	282	0.83
chr22_39688482_39688637	0.26	RP3-333H23.8		434	0.73
chr1_183776609_183776992	0.26	RGL1	ral guanine nucleotide dissociation stimulator-like 1	2510	0.36
chr8_144426889_144427132	0.26	TOP1MT	topoisomerase (DNA) I, mitochondrial	144	0.92
chr11_46354904_46355055	0.25	DGKZ	diacylglycerol kinase, zeta	524	0.74
chr4_74702622_74702974	0.25	CXCL6	chemokine (C-X-C motif) ligand 6	441	0.79
chr8_37822610_37823607	0.25	ADRB3	adrenoceptor beta 3	1375	0.34
chr16_75146149_75146377	0.25	RP11-252E2.1		1653	0.29
chr20_23112900_23113067	0.25	ENSG00000201527	.	28625	0.16
chr6_611191_611411	0.25	HUS1B	HUS1 checkpoint homolog b (S. pombe)	45662	0.17
chr20_37434180_37434422	0.25	PPP1R16B	protein phosphatase 1, regulatory subunit 16B	47	0.98
chr2_61153043_61153424	0.25	ENSG00000201076	.	14795	0.19
chr12_654579_654730	0.25	B4GALNT3	beta-1,4-N-acetyl-galactosaminyl transferase 3	2355	0.27
chr2_1719640_1719791	0.25	PXDN	peroxidasin homolog (Drosophila)	23373	0.24
chr11_33913420_33913571	0.25	LMO2	LIM domain only 2 (rhombotin-like 1)	341	0.89
chr9_37993909_37994194	0.25	ENSG00000251745	.	57286	0.12
chr2_26842102_26842377	0.25	CIB4	calcium and integrin binding family member 4	21997	0.16
chr10_134235955_134236340	0.25	RP11-432J24.3		18841	0.16
chr14_75750143_75750654	0.25	FOS	FBJ murine osteosarcoma viral oncogene homolog	3502	0.2
chr17_36607297_36607925	0.25	ENSG00000260833	.	321	0.87
chr12_132337369_132337604	0.25	MMP17	matrix metallopeptidase 17 (membrane-inserted)	7646	0.18
chr2_65245457_65245908	0.25	AC007386.4		18949	0.14
chr1_27425346_27425645	0.25	SLC9A1	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1	55478	0.1
chr11_62165677_62166025	0.25	CTD-2531D15.5		5007	0.13
chr8_20080467_20080618	0.25	ENSG00000222267	.	6748	0.19
chr20_19400174_19400351	0.24	ENSG00000221748	.	78322	0.1
chr10_114910849_114911081	0.24	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	123	0.98
chr3_71591322_71591805	0.24	ENSG00000221264	.	323	0.83
chr19_18575933_18576241	0.24	ELL	elongation factor RNA polymerase II	10656	0.1
chr10_30131086_30131237	0.24	SVIL	supervillin	106428	0.07
chr17_42439251_42439402	0.24	FAM171A2	family with sequence similarity 171, member A2	1917	0.19
chr6_41237505_41237689	0.24	TREM1	triggering receptor expressed on myeloid cells 1	16806	0.12
chr18_457195_458136	0.24	RP11-720L2.2		33249	0.16
chr10_45459580_45459731	0.24	RASSF4	Ras association (RalGDS/AF-6) domain family member 4	4376	0.13
chrX_13781833_13781984	0.24	GPM6B	glycoprotein M6B	17216	0.18
chr1_212846104_212846393	0.24	ENSG00000207491	.	19358	0.14
chr2_112078288_112078465	0.24	ENSG00000266139	.	292	0.95
chr11_10415533_10415783	0.24	ENSG00000221574	.	5206	0.23
chr7_100411285_100411882	0.24	ENSG00000263672	.	7303	0.11
chr16_83847971_83848200	0.24	HSBP1	heat shock factor binding protein 1	6491	0.17
chr4_8192745_8193409	0.24	SH3TC1	SH3 domain and tetratricopeptide repeats 1	8014	0.22
chr2_113998730_113999135	0.24	PAX8	paired box 8	328	0.68
chr15_101709991_101710273	0.24	CHSY1	chondroitin sulfate synthase 1	82005	0.08
chr16_30472246_30472632	0.24	ENSG00000202476	.	7021	0.06
chr11_61772679_61772890	0.24	AP003733.1	Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801	37331	0.11
chr19_59070081_59070232	0.24	UBE2M	ubiquitin-conjugating enzyme E2M	165	0.67
chr1_150244620_150245106	0.24	C1orf54	chromosome 1 open reading frame 54	239	0.83
chr16_88220538_88220993	0.24	BANP	BTG3 associated nuclear protein	217141	0.02
chr17_39653994_39654145	0.24	AC019349.5		3166	0.1
chr7_47468160_47468311	0.24	TNS3	tensin 3	24594	0.28
chr2_164204929_164205164	0.24	ENSG00000200902	.	59541	0.17
chr9_136208794_136209274	0.23	ENSG00000201451	.	4373	0.07
chr6_6320898_6321233	0.23	F13A1	coagulation factor XIII, A1 polypeptide	2	0.99
chr18_76402714_76403159	0.23	ENSG00000201723	.	98748	0.09
chr1_15550360_15550511	0.23	FHAD1	forkhead-associated (FHA) phosphopeptide binding domain 1	23333	0.18
chr17_76913711_76913933	0.23	TIMP2	TIMP metallopeptidase inhibitor 2	4661	0.16
chr8_103910793_103910955	0.23	KB-1507C5.3		6770	0.17
chr3_15143926_15144153	0.23	ZFYVE20	zinc finger, FYVE domain containing 20	3369	0.23
chr21_45628878_45629029	0.23	AP001057.1		7780	0.13
chrX_37433312_37433498	0.23	LANCL3	LanC lantibiotic synthetase component C-like 3 (bacterial)	2500	0.41

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF12_ASCL2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0032632	interleukin-3 production(GO:0032632)
0.2	0.6	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.2	0.7	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.2	0.7	GO:0007028	cytoplasm organization(GO:0007028)
0.2	0.7	GO:0018101	protein citrullination(GO:0018101)
0.2	0.6	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.6	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.4	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.4	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.9	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.5	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1	0.5	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.5	GO:0051873	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.1	0.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.4	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.4	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.3	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.3	GO:0021508	floor plate formation(GO:0021508)
0.1	0.4	GO:0001878	response to yeast(GO:0001878)
0.1	0.3	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.3	GO:0001714	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.5	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.1	0.3	GO:0008228	opsonization(GO:0008228)
0.1	0.4	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.6	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	0.5	GO:0030321	transepithelial chloride transport(GO:0030321)
0.1	0.3	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.1	GO:0070254	mucus secretion(GO:0070254)
0.1	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.1	0.3	GO:0010193	response to ozone(GO:0010193)
0.1	0.1	GO:0033505	floor plate morphogenesis(GO:0033505)
0.1	0.3	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.2	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.2	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.5	GO:1902624	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.1	0.2	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1	0.2	GO:0003161	cardiac conduction system development(GO:0003161)
0.1	0.2	GO:0008215	spermine metabolic process(GO:0008215)
0.1	0.2	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.1	GO:0044557	relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.1	0.2	GO:0051014	actin filament severing(GO:0051014)
0.1	0.2	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.3	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.2	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.6	GO:0043277	apoptotic cell clearance(GO:0043277)
0.1	0.1	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.1	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1	0.5	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.1	0.2	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.1	0.2	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1	0.1	GO:0072179	nephric duct formation(GO:0072179)
0.1	0.4	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.3	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.3	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.1	0.2	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	0.2	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.3	GO:0021535	cell migration in hindbrain(GO:0021535)
0.1	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.4	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	0.3	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1	0.2	GO:2000846	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.1	0.3	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.0	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.3	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.2	GO:0060406	positive regulation of penile erection(GO:0060406)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:0032971	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.1	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.2	GO:0010935	macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.2	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0048840	otolith development(GO:0048840)
0.0	0.8	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.2	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.1	GO:0033622	integrin activation(GO:0033622)
0.0	0.1	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.2	GO:0016102	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.4	GO:0002040	sprouting angiogenesis(GO:0002040)
0.0	0.3	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.2	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.2	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.2	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.5	GO:0050832	defense response to fungus(GO:0050832)
0.0	0.8	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.1	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0032329	serine transport(GO:0032329)
0.0	0.1	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.3	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.3	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.2	GO:0034033	coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.2	GO:0007549	dosage compensation(GO:0007549)
0.0	0.3	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0060174	limb bud formation(GO:0060174)
0.0	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.2	GO:0032462	regulation of protein homooligomerization(GO:0032462)
0.0	0.1	GO:0001553	luteinization(GO:0001553)
0.0	0.3	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.2	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.2	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.5	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.1	GO:1901889	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0016265	obsolete death(GO:0016265)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0060535	lung growth(GO:0060437) trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.2	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.0	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.4	GO:0006662	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.2	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.2	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.2	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0072193	positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0	0.3	GO:0048844	artery morphogenesis(GO:0048844)
0.0	0.0	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:0009186	deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0061098	positive regulation of protein tyrosine kinase activity(GO:0061098)
0.0	0.0	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.0	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.1	GO:0051957	positive regulation of amino acid transport(GO:0051957)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.0	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.0	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.2	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.1	GO:0001967	suckling behavior(GO:0001967)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.1	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0	0.1	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.1	GO:0006168	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.0	GO:0034443	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0043049	otic placode formation(GO:0043049)
0.0	0.1	GO:0035307	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine development(GO:0060998) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.2	GO:0032438	melanosome organization(GO:0032438)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.2	GO:0030865	cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.0	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.4	GO:0009081	branched-chain amino acid metabolic process(GO:0009081)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.0	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.0	GO:0010658	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.1	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.2	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.1	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.0	GO:0019532	oxalate transport(GO:0019532)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.0	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.0	0.1	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) inositol phosphate catabolic process(GO:0071545)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:0043576	regulation of respiratory gaseous exchange(GO:0043576)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.0	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.0	GO:0009130	pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.0	GO:0071624	positive regulation of granulocyte chemotaxis(GO:0071624)
0.0	0.0	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.0	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.0	0.2	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.0	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.0	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.2	GO:0042116	macrophage activation(GO:0042116)
0.0	0.1	GO:1903393	positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.2	GO:0006086	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.2	GO:0031114	negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0	0.5	GO:0072512	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.0	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.0	GO:0021877	forebrain neuron fate commitment(GO:0021877) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:1901998	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.0	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.0	0.1	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.2	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.4	GO:0006826	iron ion transport(GO:0006826)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.0	GO:0045064	T-helper 2 cell differentiation(GO:0045064)
0.0	0.1	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.0	GO:0060179	male courtship behavior(GO:0008049) male mating behavior(GO:0060179)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.0	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.0	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.0	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.1	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.0	GO:0060677	ureteric bud elongation(GO:0060677)
0.0	0.1	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.2	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0051709	regulation of killing of cells of other organism(GO:0051709)
0.0	0.0	GO:0001562	response to protozoan(GO:0001562)
0.0	0.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.0	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.0	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.2	GO:0048484	enteric nervous system development(GO:0048484)
0.0	0.0	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.0	GO:0002888	positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.0	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	0.0	GO:0032691	negative regulation of interleukin-1 beta production(GO:0032691)
0.0	0.2	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.0	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0070391	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.3	GO:0030071	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0	0.0	GO:0072070	loop of Henle development(GO:0072070)
0.0	0.0	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.0	GO:0032493	response to bacterial lipoprotein(GO:0032493) detection of bacterial lipoprotein(GO:0042494) positive regulation of interleukin-6 biosynthetic process(GO:0045410) response to bacterial lipopeptide(GO:0070339) detection of bacterial lipopeptide(GO:0070340) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0	0.1	GO:0051096	positive regulation of helicase activity(GO:0051096)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.6	GO:0005915	zonula adherens(GO:0005915)
0.1	0.3	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.3	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1	0.3	GO:0042599	lamellar body(GO:0042599)
0.1	0.2	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.3	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.4	GO:0031941	filamentous actin(GO:0031941)
0.0	0.2	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.4	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.3	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.2	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.6	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.2	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.4	GO:0032982	myosin filament(GO:0032982)
0.0	0.2	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.4	GO:0032421	stereocilium bundle(GO:0032421)
0.0	0.0	GO:0098651	basement membrane collagen trimer(GO:0098651)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.0	GO:0000805	X chromosome(GO:0000805)
0.0	0.0	GO:0031904	endosome lumen(GO:0031904)
0.0	0.0	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.0	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.4	GO:0030018	Z disc(GO:0030018)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.5	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.2	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.0	GO:0071547	piP-body(GO:0071547)
0.0	0.3	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	0.7	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.4	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.4	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.1	0.4	GO:0001849	complement component C1q binding(GO:0001849)
0.1	0.5	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.4	GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1	0.4	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	0.4	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.1	0.6	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.3	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	1.0	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.3	GO:0043559	insulin binding(GO:0043559)
0.1	0.8	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1	0.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.3	GO:0004340	glucokinase activity(GO:0004340)
0.1	0.2	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.3	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.4	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.4	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	0.2	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.7	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.3	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.2	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	0.2	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1	0.2	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.1	0.3	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.1	0.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.3	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	0.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.4	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.1	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.4	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.3	GO:0009374	biotin binding(GO:0009374)
0.1	0.2	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.3	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.1	0.2	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	0.2	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.3	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.6	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.2	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.2	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.4	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.3	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.2	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.6	GO:0019894	kinesin binding(GO:0019894)
0.0	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.2	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.3	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	1.6	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.2	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.3	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.2	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.4	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.2	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.2	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.0	GO:0032142	single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0	0.2	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.3	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.2	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.0	0.2	GO:0042171	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.6	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.5	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.4	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.0	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.2	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.0	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.2	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.0	GO:0001846	opsonin binding(GO:0001846)
0.0	0.0	GO:0033265	choline binding(GO:0033265)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.3	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0016918	retinal binding(GO:0016918)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.0	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.0	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.1	GO:0010851	cyclase regulator activity(GO:0010851)
0.0	0.2	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.5	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.0	GO:0042806	fucose binding(GO:0042806)
0.0	0.0	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.2	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.2	GO:1901682	sulfur compound transmembrane transporter activity(GO:1901682)
0.0	0.0	GO:0030354	melanin-concentrating hormone activity(GO:0030354)
0.0	0.0	GO:0016885	ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.1	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.0	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.0	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.1	GO:0031420	alkali metal ion binding(GO:0031420)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.0	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.0	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.0	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.3	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.0	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.3	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.1	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	3.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.5	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	0.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	1.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	0.5	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.7	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.0	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.3	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.0	REACTOME PLATELET HOMEOSTASIS	Genes involved in Platelet homeostasis
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.6	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.5	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.1	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.4	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.3	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	1.1	REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS	Genes involved in Glycerophospholipid biosynthesis
0.0	0.0	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.1	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.0	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.1	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.0	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts

Results for TCF12_ASCL2

Z-value: 1.45

Motif logo

Transcription factors associated with TCF12_ASCL2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the TCF12_ASCL2 motif across conditions

Conditions sorted by the z-value of the TCF12_ASCL2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF12_ASCL2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: