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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TCF21

Z-value: 1.59

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Transcription factors associated with TCF21

Gene Symbol	Gene ID	Gene Info
TCF21 Ensembl NCBI GeneCards UniProt	ENSG00000118526.6	TCF21

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
TCF21	chr6_134210511_134210662	113	0.841016	0.37	3.3e-01	Click!
TCF21	chr6_134210875_134211079	504	0.634825	0.23	5.4e-01	Click!

Activity of the TCF21 motif across conditions

Conditions sorted by the z-value of the TCF21 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_37355725_37356299	1.16	ELMO1	engulfment and cell motility 1	26355	0.19
chr12_122327188_122327339	0.86	PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	571	0.69
chr17_3865194_3865538	0.70	ATP2A3	ATPase, Ca++ transporting, ubiquitous	2219	0.29
chr2_198127644_198128365	0.66	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	39239	0.13
chr3_13459505_13459764	0.65	NUP210	nucleoporin 210kDa	2175	0.38
chr6_130040950_130041101	0.61	ARHGAP18	Rho GTPase activating protein 18	9655	0.25
chr13_51465573_51465808	0.59	RNASEH2B-AS1	RNASEH2B antisense RNA 1	88	0.97
chr19_16228666_16229162	0.59	RAB8A	RAB8A, member RAS oncogene family	6207	0.14
chr1_169659354_169659683	0.59	SELL	selectin L	21321	0.18
chr2_99068894_99069462	0.59	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	7765	0.25
chr8_71065997_71066240	0.58	NCOA2	nuclear receptor coactivator 2	5423	0.28
chr22_17597863_17598182	0.56	CECR6	cat eye syndrome chromosome region, candidate 6	4121	0.17
chr20_32625730_32625931	0.55	RALY	RALY heterogeneous nuclear ribonucleoprotein	8163	0.18
chr10_11255119_11255520	0.55	RP3-323N1.2		41980	0.16
chr6_37939838_37940078	0.54	ZFAND3	zinc finger, AN1-type domain 3	42223	0.17
chr2_109831211_109831453	0.54	ENSG00000264934	.	73288	0.11
chr7_40638110_40638340	0.53	AC004988.1		51698	0.18
chr8_29964950_29965250	0.53	LEPROTL1	leptin receptor overlapping transcript-like 1	5644	0.16
chr13_114942302_114942453	0.53	RASA3	RAS p21 protein activator 3	44291	0.13
chr9_101855594_101855850	0.52	TGFBR1	transforming growth factor, beta receptor 1	10598	0.23
chr3_186756396_186756829	0.51	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	4919	0.27
chr7_99070775_99071043	0.51	ZNF789	zinc finger protein 789	374	0.72
chr7_150200817_150201275	0.51	GIMAP7	GTPase, IMAP family member 7	10872	0.18
chr17_76757237_76757578	0.51	CYTH1	cytohesin 1	20947	0.17
chr9_130544922_130545267	0.51	CDK9	cyclin-dependent kinase 9	2864	0.12
chr1_40558034_40558185	0.50	PPT1	palmitoyl-protein thioesterase 1	346	0.88
chr12_6573393_6573619	0.50	VAMP1	vesicle-associated membrane protein 1 (synaptobrevin 1)	6305	0.09
chr15_77291339_77291587	0.50	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	3548	0.24
chr9_117141639_117141997	0.50	AKNA	AT-hook transcription factor	1903	0.36
chr2_65258054_65258356	0.49	AC007386.4		6426	0.18
chr20_43996117_43996734	0.49	SYS1	SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)	4331	0.13
chr16_68107852_68108775	0.48	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	10934	0.1
chr6_24919737_24919924	0.48	FAM65B	family with sequence similarity 65, member B	8635	0.23
chr2_158271446_158271770	0.48	CYTIP	cytohesin 1 interacting protein	24318	0.19
chr19_4114356_4114678	0.48	MAP2K2	mitogen-activated protein kinase kinase 2	9597	0.12
chr17_25622305_25622549	0.47	WSB1	WD repeat and SOCS box containing 1	1055	0.47
chr16_57723929_57724123	0.47	CCDC135	coiled-coil domain containing 135	4679	0.15
chr9_130789981_130790132	0.47	RP11-379C10.1		29585	0.09
chr1_231112171_231112375	0.47	TTC13	tetratricopeptide repeat domain 13	2269	0.21
chr9_139423168_139423365	0.47	ENSG00000263403	.	9188	0.1
chr3_71440657_71441270	0.46	FOXP1	forkhead box P1	87052	0.09
chr9_92094224_92094387	0.46	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	500	0.84
chr20_1344193_1344436	0.46	RP11-314N13.3		2048	0.25
chr17_75440529_75440804	0.46	ENSG00000200651	.	2475	0.23
chr16_85342323_85342695	0.46	ENSG00000266307	.	2578	0.35
chr16_68453315_68453501	0.46	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	28987	0.12
chr3_184356140_184356339	0.46	MAGEF1	melanoma antigen family F, 1	73597	0.09
chr6_166830402_166830553	0.46	RP1-168L15.5		33800	0.13
chr2_234265257_234265461	0.46	DGKD	diacylglycerol kinase, delta 130kDa	2205	0.23
chr10_11243448_11243865	0.45	RP3-323N1.2		30317	0.19
chr2_173464495_173464646	0.45	ENSG00000199866	.	41590	0.12
chr7_128581367_128581518	0.45	IRF5	interferon regulatory factor 5	716	0.63
chr11_48044517_48044998	0.45	AC103828.1		7350	0.22
chr8_71519355_71519651	0.44	TRAM1	translocation associated membrane protein 1	510	0.64
chr10_11234420_11234733	0.44	RP3-323N1.2		21237	0.2
chr1_114428898_114429049	0.44	BCL2L15	BCL2-like 15	1024	0.4
chr10_46053827_46054093	0.44	MARCH8	membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase	23118	0.22
chr9_80688635_80688798	0.44	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	42342	0.2
chr7_50357344_50357742	0.44	IKZF1	IKAROS family zinc finger 1 (Ikaros)	9225	0.29
chr10_50390146_50390361	0.44	C10orf128	chromosome 10 open reading frame 128	6104	0.2
chr1_110348199_110348535	0.44	EPS8L3	EPS8-like 3	41718	0.11
chr10_111972940_111973241	0.44	MXI1	MAX interactor 1, dimerization protein	3101	0.27
chr16_23941301_23941452	0.43	PRKCB	protein kinase C, beta	92832	0.08
chr7_155387096_155387344	0.43	AC009403.2	Protein LOC100506302	49875	0.12
chr13_41901675_41901927	0.43	NAA16	N(alpha)-acetyltransferase 16, NatA auxiliary subunit	16385	0.17
chr16_20855857_20856092	0.43	AC004381.6	Putative RNA exonuclease NEF-sp	16128	0.14
chr18_74433068_74433534	0.43	ENSG00000252097	.	79429	0.09
chr6_11331844_11332182	0.43	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	50519	0.16
chr2_7064329_7064480	0.43	ENSG00000228203	.	5564	0.2
chr1_145928317_145928496	0.43	PDZK1P1	PDZ domain containing 1 pseudogene 1	11707	0.16
chr1_111769513_111769681	0.43	CHI3L2	chitinase 3-like 2	41	0.97
chr12_4939072_4939447	0.43	RP3-377H17.2		8862	0.2
chr11_118085246_118085456	0.43	AMICA1	adhesion molecule, interacts with CXADR antigen 1	255	0.9
chr17_37790895_37791174	0.42	STARD3	StAR-related lipid transfer (START) domain containing 3	2284	0.19
chr7_129543806_129543957	0.42	UBE2H	ubiquitin-conjugating enzyme E2H	47286	0.1
chr6_52848822_52849150	0.42	ENSG00000252106	.	4933	0.15
chr16_67679907_67680264	0.42	RLTPR	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	935	0.38
chr7_104985736_104986011	0.42	ENSG00000201179	.	12636	0.21
chr10_73579061_73579212	0.42	CDH23	cadherin-related 23	23608	0.15
chr1_117307462_117307691	0.42	CD2	CD2 molecule	10487	0.22
chr19_51631705_51632123	0.42	SIGLEC9	sialic acid binding Ig-like lectin 9	1627	0.2
chr1_23917941_23918174	0.42	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	31772	0.13
chr16_68109877_68110028	0.42	NFATC3	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3	9295	0.1
chr2_231508120_231508337	0.42	ENSG00000199791	.	56392	0.11
chr20_56049819_56050110	0.42	CTCFL	CCCTC-binding factor (zinc finger protein)-like	49349	0.12
chr9_117379407_117379732	0.42	ENSG00000272241	.	742	0.54
chr17_80398931_80399097	0.42	C17orf62	chromosome 17 open reading frame 62	3390	0.11
chr15_64152477_64152628	0.42	ENSG00000199156	.	10666	0.21
chr1_156494924_156495366	0.41	ENSG00000238843	.	3977	0.14
chr6_33882815_33883519	0.41	ENSG00000221697	.	84661	0.08
chr6_37940260_37940411	0.41	ZFAND3	zinc finger, AN1-type domain 3	42600	0.17
chr7_50425689_50425900	0.41	IKZF1	IKAROS family zinc finger 1 (Ikaros)	58549	0.13
chr1_9142777_9142958	0.41	ENSG00000252404	.	112	0.96
chr3_18765552_18765703	0.41	ENSG00000228956	.	21609	0.29
chr16_68403810_68404248	0.41	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	879	0.49
chr19_36443325_36443510	0.41	LRFN3	leucine rich repeat and fibronectin type III domain containing 3	15395	0.09
chr13_51467249_51467539	0.41	RNASEH2B-AS1	RNASEH2B antisense RNA 1	1616	0.39
chr1_6066778_6067032	0.41	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	14134	0.17
chr5_137696561_137697050	0.41	KDM3B	lysine (K)-specific demethylase 3B	8520	0.13
chr3_71169321_71169645	0.41	FOXP1	forkhead box P1	10261	0.31
chr12_110787174_110787572	0.41	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	3367	0.22
chr12_65085302_65085472	0.41	AC025262.1	Mesenchymal stem cell protein DSC96; Uncharacterized protein	4942	0.17
chr21_43673739_43673890	0.41	ABCG1	ATP-binding cassette, sub-family G (WHITE), member 1	2380	0.26
chr15_60834363_60834558	0.40	CTD-2501E16.2		12288	0.19
chr2_25556807_25556990	0.40	ENSG00000221445	.	5308	0.23
chr12_3863154_3863452	0.40	EFCAB4B	EF-hand calcium binding domain 4B	937	0.65
chr13_108918288_108918449	0.40	TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	3609	0.26
chr7_142416762_142417045	0.40	PRSS1	protease, serine, 1 (trypsin 1)	40416	0.14
chr9_134132866_134133138	0.40	FAM78A	family with sequence similarity 78, member A	12878	0.16
chr14_100530418_100530577	0.40	EVL	Enah/Vasp-like	1118	0.45
chr12_94520148_94520475	0.40	PLXNC1	plexin C1	22188	0.21
chr7_102066247_102066509	0.40	ORAI2	ORAI calcium release-activated calcium modulator 2	7175	0.09
chrX_39945838_39946068	0.40	BCOR	BCL6 corepressor	10703	0.31
chr4_153476062_153476235	0.40	ENSG00000268471	.	18568	0.19
chr2_24730436_24730587	0.40	NCOA1	nuclear receptor coactivator 1	15584	0.23
chr7_76033311_76033487	0.40	SRCRB4D	scavenger receptor cysteine rich domain containing, group B (4 domains)	5613	0.17
chr22_40606032_40606518	0.39	TNRC6B	trinucleotide repeat containing 6B	32329	0.2
chr1_169673193_169673400	0.39	SELL	selectin L	7543	0.2
chr12_9142586_9142783	0.39	KLRG1	killer cell lectin-like receptor subfamily G, member 1	467	0.78
chr15_64152644_64152888	0.39	ENSG00000199156	.	10452	0.21
chr1_147470017_147470168	0.39	ENSG00000206791	.	16723	0.19
chr17_72636963_72637310	0.39	CD300E	CD300e molecule	17239	0.12
chr6_25085634_25085917	0.39	FAM65B	family with sequence similarity 65, member B	43537	0.13
chr11_47417148_47417745	0.39	RP11-750H9.5		255	0.83
chr3_177722273_177722502	0.39	ENSG00000199858	.	3180	0.41
chr14_38547030_38547196	0.39	CTD-2058B24.2		13250	0.26
chr2_144991938_144992399	0.39	GTDC1	glycosyltransferase-like domain containing 1	1136	0.67
chr20_62266848_62267088	0.39	CTD-3184A7.4		8365	0.1
chr14_106559690_106559937	0.38	IGHV2-10	immunoglobulin heavy variable 2-10 (pseudogene)	162	0.82
chr9_136567139_136567359	0.38	SARDH	sarcosine dehydrogenase	1574	0.4
chr11_67180703_67180854	0.38	CARNS1	carnosine synthase 1	2371	0.11
chr2_233958417_233958732	0.38	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	33385	0.16
chr20_50111298_50111661	0.38	ENSG00000266761	.	41965	0.17
chr2_136815642_136816045	0.38	AC093391.2		45808	0.15
chr3_3215472_3215973	0.38	CRBN	cereblon	5636	0.2
chr11_57480467_57480618	0.38	TMX2	thioredoxin-related transmembrane protein 2	463	0.58
chr11_118096084_118096517	0.38	AMICA1	adhesion molecule, interacts with CXADR antigen 1	491	0.74
chr9_130473685_130473878	0.38	C9orf117	chromosome 9 open reading frame 117	388	0.73
chr1_40526375_40526591	0.38	CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	19929	0.16
chr7_37372413_37372643	0.38	ELMO1	engulfment and cell motility 1	9839	0.22
chr14_102293722_102294111	0.38	CTD-2017C7.1		11952	0.15
chrX_19707338_19707501	0.38	SH3KBP1	SH3-domain kinase binding protein 1	18303	0.28
chr2_178175389_178175567	0.38	NFE2L2	nuclear factor, erythroid 2-like 2	527	0.65
chr13_114943882_114944143	0.37	RASA3	RAS p21 protein activator 3	45926	0.12
chr17_47296320_47296793	0.37	ABI3	ABI family, member 3	369	0.83
chr5_55982131_55982429	0.37	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	80221	0.09
chr11_121248929_121249080	0.37	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	73908	0.11
chr1_160421706_160421992	0.37	ENSG00000223009	.	51397	0.08
chr3_107820810_107821187	0.37	CD47	CD47 molecule	11126	0.3
chr16_50302510_50302661	0.37	ADCY7	adenylate cyclase 7	2123	0.34
chr12_116565358_116565509	0.37	ENSG00000207967	.	21026	0.2
chrX_128913033_128913442	0.37	SASH3	SAM and SH3 domain containing 3	723	0.69
chr1_23852013_23852546	0.37	E2F2	E2F transcription factor 2	5433	0.19
chr14_22891394_22891545	0.37	ENSG00000251002	.	10250	0.12
chr6_167532699_167533025	0.37	CCR6	chemokine (C-C motif) receptor 6	3395	0.24
chr17_33755333_33755563	0.37	SLFN12	schlafen family member 12	4095	0.17
chr13_103254814_103255003	0.37	TPP2	tripeptidyl peptidase II	5535	0.22
chrX_78290821_78291202	0.37	P2RY10	purinergic receptor P2Y, G-protein coupled, 10	90093	0.1
chr14_101292986_101293251	0.37	AL117190.2		2419	0.08
chr5_50007609_50007805	0.37	PARP8	poly (ADP-ribose) polymerase family, member 8	44316	0.21
chr2_197896638_197896865	0.37	ANKRD44	ankyrin repeat domain 44	31525	0.21
chr12_111132257_111132529	0.36	HVCN1	hydrogen voltage-gated channel 1	4779	0.2
chr5_75720726_75721410	0.36	IQGAP2	IQ motif containing GTPase activating protein 2	20819	0.25
chr11_4028359_4028548	0.36	STIM1	stromal interaction molecule 1	51526	0.12
chr18_2966742_2967011	0.36	RP11-737O24.1		140	0.95
chr11_14633437_14633654	0.36	PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	31618	0.18
chr7_8054995_8055386	0.36	AC006042.7		45656	0.13
chr2_198132325_198132480	0.36	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	34841	0.14
chr2_162852228_162852540	0.36	ENSG00000253046	.	77092	0.09
chr5_133437343_133437771	0.36	TCF7	transcription factor 7 (T-cell specific, HMG-box)	12845	0.22
chr12_45222790_45222976	0.36	NELL2	NEL-like 2 (chicken)	46368	0.17
chr1_114482835_114483579	0.36	HIPK1	homeodomain interacting protein kinase 1	9857	0.13
chr19_39140186_39140636	0.36	ACTN4	actinin, alpha 4	2033	0.22
chr9_136207810_136207991	0.36	ENSG00000201451	.	3239	0.09
chr8_101506449_101506707	0.36	KB-1615E4.3		1822	0.33
chr16_2204860_2205013	0.36	ENSG00000206630	.	170	0.78
chr1_234977814_234977965	0.36	ENSG00000201638	.	4169	0.31
chr3_193433845_193434101	0.36	ENSG00000243991	.	24537	0.2
chr4_26887074_26887318	0.36	STIM2	stromal interaction molecule 2	24115	0.21
chr1_155938649_155938876	0.36	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	758	0.45
chr3_4334086_4334379	0.36	SETMAR	SET domain and mariner transposase fusion gene	10756	0.31
chr9_136208045_136208226	0.36	ENSG00000201451	.	3474	0.08
chr17_26135588_26135739	0.36	NOS2	nitric oxide synthase 2, inducible	8138	0.21
chr4_42630132_42630439	0.36	ATP8A1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1	28825	0.2
chr18_68339531_68339691	0.36	GTSCR1	Gilles de la Tourette syndrome chromosome region, candidate 1	21631	0.28
chr17_72458858_72459009	0.36	CD300A	CD300a molecule	3622	0.18
chr11_118110321_118110509	0.36	MPZL3	myelin protein zero-like 3	12647	0.13
chr15_83419735_83419886	0.36	RP11-752G15.6		474	0.7
chr3_47031490_47031641	0.36	NBEAL2	neurobeachin-like 2	5246	0.2
chr15_81585979_81586156	0.36	IL16	interleukin 16	3187	0.26
chr9_92082755_92083098	0.35	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	11879	0.23
chr12_120445548_120445820	0.35	CCDC64	coiled-coil domain containing 64	18011	0.19
chr1_38312102_38312253	0.35	MTF1	metal-regulatory transcription factor 1	13115	0.09
chr2_429739_429917	0.35	FAM150B	family with sequence similarity 150, member B	140977	0.04
chr1_154925484_154925883	0.35	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	2897	0.11
chr10_7088660_7089557	0.35	SFMBT2	Scm-like with four mbt domains 2	361599	0.01
chr15_70853193_70853484	0.35	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	141282	0.05
chr2_62430640_62430961	0.35	ENSG00000266097	.	2161	0.29
chr11_63319015_63319219	0.35	HRASLS2	HRAS-like suppressor 2	11738	0.14
chrX_12969294_12969579	0.35	TMSB4X	thymosin beta 4, X-linked	23791	0.18

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.2	0.6	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.2	0.5	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.2	0.7	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.6	GO:0048548	regulation of pinocytosis(GO:0048548)
0.1	0.5	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.4	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.4	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1	0.8	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.1	0.1	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1	0.3	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	0.3	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.3	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	0.7	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1	0.4	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.2	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.6	GO:0002063	chondrocyte development(GO:0002063)
0.1	0.3	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.1	0.3	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.1	0.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.4	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.2	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.4	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1	0.2	GO:0032328	alanine transport(GO:0032328)
0.1	0.3	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.2	GO:0045047	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.1	0.2	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.1	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.3	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.2	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1	0.2	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.3	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.1	0.1	GO:0002507	tolerance induction(GO:0002507)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.2	GO:0070266	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.1	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.3	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.1	0.4	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.2	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.1	0.1	GO:0002604	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1	0.6	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	0.1	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1	0.2	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1	0.1	GO:0046633	NK T cell proliferation(GO:0001866) alpha-beta T cell proliferation(GO:0046633) NK T cell activation(GO:0051132)
0.1	0.5	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.3	GO:0043383	negative T cell selection(GO:0043383)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.2	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.1	0.4	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.1	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.1	0.2	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.1	GO:0031223	auditory behavior(GO:0031223)
0.1	0.1	GO:0051712	positive regulation of killing of cells of other organism(GO:0051712)
0.1	0.4	GO:0002834	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.1	0.3	GO:0008354	germ cell migration(GO:0008354)
0.0	0.2	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.1	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812)
0.0	0.4	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.2	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.0	GO:0002820	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.0	0.1	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.0	GO:0010872	regulation of cholesterol esterification(GO:0010872)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.2	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.2	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.3	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0061526	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0	0.1	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.6	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.1	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0	0.0	GO:0002448	mast cell mediated immunity(GO:0002448)
0.0	1.2	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:1900087	traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.2	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.1	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.5	GO:0006906	vesicle fusion(GO:0006906)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.3	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	2.3	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.4	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.2	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.2	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.0	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.8	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.1	GO:0002740	negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0	0.1	GO:0042832	response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.0	GO:0002577	regulation of antigen processing and presentation(GO:0002577) positive regulation of antigen processing and presentation(GO:0002579)
0.0	0.3	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.1	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.1	GO:0031848	telomere capping(GO:0016233) protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.6	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.2	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.8	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.2	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.1	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.1	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0016241	regulation of macroautophagy(GO:0016241)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.3	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.4	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.2	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.0	GO:0070198	positive regulation of telomere maintenance(GO:0032206) protein localization to chromosome, telomeric region(GO:0070198)
0.0	0.2	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.2	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.0	GO:1902750	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) negative regulation of cell cycle G2/M phase transition(GO:1902750)
0.0	0.0	GO:0034587	piRNA metabolic process(GO:0034587)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.2	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.0	GO:0032613	interleukin-10 production(GO:0032613)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.0	GO:0034776	response to histamine(GO:0034776)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.3	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
0.0	0.2	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.4	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.1	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0071347	cellular response to interleukin-1(GO:0071347)
0.0	0.1	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.2	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.0	GO:2000516	positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.1	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.0	GO:0042321	negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754)
0.0	0.0	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.1	GO:0002829	regulation of type 2 immune response(GO:0002828) negative regulation of type 2 immune response(GO:0002829)
0.0	0.4	GO:0043967	histone H4 acetylation(GO:0043967)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.2	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.2	GO:0045576	mast cell activation(GO:0045576)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.0	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.0	GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003339)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0045954	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.4	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.1	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.1	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.2	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.1	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.0	GO:0090197	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0	0.0	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.5	GO:0033572	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.0	GO:0002238	response to molecule of fungal origin(GO:0002238)
0.0	0.1	GO:0031297	replication fork processing(GO:0031297)
0.0	0.1	GO:0051806	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0015893	drug transport(GO:0015893)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.3	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.7	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0051299	centrosome separation(GO:0051299)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0045006	DNA deamination(GO:0045006)
0.0	0.3	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.1	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.0	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.0	GO:0001820	serotonin secretion(GO:0001820)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.1	GO:0019614	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.0	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.0	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.0	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.6	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.1	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.0	GO:1903901	negative regulation of viral process(GO:0048525) negative regulation of viral life cycle(GO:1903901)
0.0	0.0	GO:0016265	obsolete death(GO:0016265)
0.0	0.0	GO:0010536	regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.0	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.0	0.2	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.0	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.0	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.1	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.0	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.2	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.3	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.1	GO:0021612	facial nerve development(GO:0021561) cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) anatomical structure arrangement(GO:0048532)
0.0	0.0	GO:0033700	phospholipid efflux(GO:0033700)
0.0	0.0	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0	0.0	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.1	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.2	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.0	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.3	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0015695	organic cation transport(GO:0015695)
0.0	0.0	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.0	GO:0030320	cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.0	GO:0032801	receptor catabolic process(GO:0032801)
0.0	0.0	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0060678	sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935) dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0	0.6	GO:1902400	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0014823	response to activity(GO:0014823)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0046348	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.0	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0051955	regulation of amino acid transport(GO:0051955)
0.0	0.0	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.0	GO:0035725	sodium ion transmembrane transport(GO:0035725)
0.0	0.0	GO:0046831	regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.0	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.0	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.0	0.0	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.0	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.2	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:0045851	pH reduction(GO:0045851)
0.0	0.1	GO:0051453	regulation of intracellular pH(GO:0051453)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0010885	regulation of cholesterol storage(GO:0010885)
0.0	0.0	GO:0048535	lymph node development(GO:0048535)
0.0	0.0	GO:0006991	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.0	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.0	GO:0090232	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.0	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.2	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.0	GO:0044406	virion attachment to host cell(GO:0019062) adhesion of symbiont to host(GO:0044406) adhesion of symbiont to host cell(GO:0044650)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.2	0.6	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.3	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.3	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.3	GO:0032009	early phagosome(GO:0032009)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.2	GO:0044462	external encapsulating structure part(GO:0044462)
0.1	0.4	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.1	0.4	GO:0000791	euchromatin(GO:0000791)
0.0	0.3	GO:0045179	apical cortex(GO:0045179)
0.0	0.4	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.3	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.5	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.4	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0070081	clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.5	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0030897	HOPS complex(GO:0030897)
0.0	0.2	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.2	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.0	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	1.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.6	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	0.8	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.6	GO:0070603	SWI/SNF superfamily-type complex(GO:0070603)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.0	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.6	GO:0055037	recycling endosome(GO:0055037)
0.0	0.6	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.3	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.9	GO:0070382	exocytic vesicle(GO:0070382)
0.0	0.2	GO:0030119	AP-type membrane coat adaptor complex(GO:0030119)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0046930	pore complex(GO:0046930)
0.0	0.1	GO:0005844	polysome(GO:0005844)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2	0.5	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.5	GO:0070492	oligosaccharide binding(GO:0070492)
0.1	0.4	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.5	GO:0004340	glucokinase activity(GO:0004340)
0.1	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.3	GO:0035197	siRNA binding(GO:0035197)
0.1	0.3	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.7	GO:0004568	chitinase activity(GO:0004568)
0.1	0.5	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.4	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1	1.0	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.3	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.2	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1	0.3	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.8	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.5	GO:0005522	profilin binding(GO:0005522)
0.1	0.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	0.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	0.3	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1	0.2	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.2	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.1	0.3	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.2	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	1.0	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.3	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.1	0.3	GO:0048156	tau protein binding(GO:0048156)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.5	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.4	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.0	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.2	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.3	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.2	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.2	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.3	GO:0019864	IgG binding(GO:0019864)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.4	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.5	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.4	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	1.3	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0015248	sterol transporter activity(GO:0015248)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.2	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0016502	purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0	0.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.3	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.3	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.6	GO:0043022	ribosome binding(GO:0043022)
0.0	0.3	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.2	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.3	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.3	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	1.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	1.4	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.2	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.1	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.2	GO:0031701	angiotensin receptor binding(GO:0031701)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.2	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.4	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.0	GO:0015199	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.6	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.3	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.3	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.3	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.0	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.4	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.0	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.0	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.0	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.0	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.4	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.0	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.2	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.3	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.0	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.3	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.3	GO:0008375	acetylglucosaminyltransferase activity(GO:0008375)
0.0	0.3	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.0	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.0	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.7	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.5	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.3	GO:0002020	protease binding(GO:0002020)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.0	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0030553	cGMP binding(GO:0030553)
0.0	0.0	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.0	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	1.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	0.5	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.3	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.5	PID BCR 5PATHWAY	BCR signaling pathway
0.0	1.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.5	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.3	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	1.2	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.4	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.5	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.6	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.3	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.4	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.0	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.5	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.3	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.3	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.0	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.2	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID MYC PATHWAY	C-MYC pathway
0.0	0.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.2	PID FOXO PATHWAY	FoxO family signaling
0.0	0.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.4	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.0	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	2.0	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.9	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.2	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1	0.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	1.2	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.7	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.4	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.3	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.8	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.6	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.8	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.0	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0	0.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.4	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	1.2	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	1.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.0	1.2	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	1.0	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.5	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	1.3	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.1	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.2	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.7	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.4	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.0	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.2	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.7	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.5	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.0	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.1	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.0	REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS	Genes involved in Acetylcholine Binding And Downstream Events
0.0	0.1	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.7	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1