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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TCF7L1

Z-value: 0.93

Motif logo

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Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
TCF7L1
ENSG00000152284.4 TCF7L1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
TCF7L1chr2_85284511_85284681759370.0843330.771.6e-02Click!
TCF7L1chr2_85282591_85282742778670.081553-0.608.9e-02Click!
TCF7L1chr2_85284961_85285173754660.0850250.561.2e-01Click!
TCF7L1chr2_85359450_8535960110080.5802870.551.2e-01Click!
TCF7L1chr2_85280075_85280226803830.0780640.462.1e-01Click!

Activity of the TCF7L1 motif across conditions

Conditions sorted by the z-value of the TCF7L1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_49946029_49946413 0.31 CAB39L
 calcium binding protein 39-like
 5046
 0.26
chr17_38182542_38182693 0.30 ENSG00000238793
 .
 1281
 0.3
chr14_68648383_68648543 0.29 ENSG00000244677
 .
 31838
 0.18
chr16_50651385_50651565 0.27 RP11-401P9.6
3880
 0.2
chr8_128840086_128840237 0.25 ENSG00000249859
 .
 31953
 0.2
chr2_109580892_109581113 0.24 EDAR
 ectodysplasin A receptor
 24723
 0.24
chr5_156319485_156319636 0.24 TIMD4
 T-cell immunoglobulin and mucin domain containing 4
 43127
 0.17
chr11_130259035_130259186 0.24 ADAMTS8
 ADAM metallopeptidase with thrombospondin type 1 motif, 8
 39778
 0.16
chr5_76625160_76625430 0.23 PDE8B
 phosphodiesterase 8B
 3777
 0.34
chr11_57449245_57449396 0.22 ZDHHC5
 zinc finger, DHHC-type containing 5
 692
 0.53
chr3_49025329_49025480 0.22 P4HTM
 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
 1915
 0.14
chr12_65094836_65094987 0.22 AC025262.1
 Mesenchymal stem cell protein DSC96; Uncharacterized protein
 4582
 0.17
chr4_4227781_4227932 0.22 OTOP1
 otopetrin 1
 760
 0.67
chr10_73862702_73862853 0.22 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 13987
 0.21
chr4_981402_981614 0.22 IDUA
 iduronidase, alpha-L-
 633
 0.46
chr1_207073979_207074130 0.22 IL24
 interleukin 24
 2876
 0.21
chr19_33662270_33662421 0.22 ENSG00000264355
 .
 5633
 0.14
chr9_98620223_98620374 0.22 ENSG00000252847
 .
 1888
 0.36
chr7_100814110_100814261 0.22 VGF
 VGF nerve growth factor inducible
 5311
 0.1
chr13_22681618_22681904 0.22 ENSG00000244197
 .
 317085
 0.01
chr14_65237977_65238128 0.21 SPTB
 spectrin, beta, erythrocytic
 11216
 0.2
chr18_67070231_67070382 0.21 DOK6
 docking protein 6
 2015
 0.5
chr17_1776866_1777017 0.21 RPA1
 replication protein A1, 70kDa
 5388
 0.17
chr2_235056234_235056385 0.21 SPP2
 secreted phosphoprotein 2, 24kDa
 96878
 0.08
chr15_87160145_87160540 0.21 RP11-182L7.1
14025
 0.31
chr16_1018736_1018887 0.21 LMF1
 lipase maturation factor 1
 2055
 0.21
chr12_124416244_124416395 0.20 DNAH10OS
 dynein, axonemal, heavy chain 10 opposite strand
 3212
 0.11
chr16_3064160_3064311 0.20 CLDN9
 claudin 9
 1778
 0.12
chr7_27278726_27278948 0.20 EVX1
 even-skipped homeobox 1
 3327
 0.13
chr13_30532983_30533134 0.20 LINC00572
 long intergenic non-protein coding RNA 572
 32270
 0.23
chr11_62285356_62285507 0.20 AHNAK
 AHNAK nucleoprotein
 18148
 0.09
chr7_537977_538128 0.19 PDGFA
 platelet-derived growth factor alpha polypeptide
 20093
 0.2
chr8_19250899_19251050 0.19 SH2D4A
 SH2 domain containing 4A
 73873
 0.13
chr2_99527888_99528039 0.19 KIAA1211L
 KIAA1211-like
 2979
 0.33
chr1_111212908_111213059 0.19 KCNA3
 potassium voltage-gated channel, shaker-related subfamily, member 3
 4672
 0.21
chr5_80400951_80401102 0.19 CTD-2193P3.2
9645
 0.28
chr1_46808965_46809116 0.19 NSUN4
 NOP2/Sun domain family, member 4
 2164
 0.27
chr7_141211304_141211601 0.18 AGK
 acylglycerol kinase
 39537
 0.14
chr16_69200425_69200916 0.18 ENSG00000207083
 .
 9010
 0.12
chr11_13317651_13317839 0.18 ARNTL
 aryl hydrocarbon receptor nuclear translocator-like
 13788
 0.26
chr2_25498362_25498513 0.18 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
 23257
 0.19
chr1_93042440_93042924 0.18 GFI1
 growth factor independent 1 transcription repressor
 90249
 0.08
chr1_168482288_168482558 0.18 XCL2
 chemokine (C motif) ligand 2
 30812
 0.2
chr7_157619868_157620019 0.18 AC011899.9
27278
 0.2
chr21_34557928_34558079 0.17 C21orf54
 chromosome 21 open reading frame 54
 15462
 0.15
chr10_105564418_105564569 0.17 SH3PXD2A
 SH3 and PX domains 2A
 3438
 0.29
chr20_415273_415424 0.17 ENSG00000206797
 .
 15959
 0.14
chr6_111908214_111908423 0.17 TRAF3IP2-AS1
 TRAF3IP2 antisense RNA 1
 12496
 0.17
chr2_237283808_237283959 0.17 RP11-785G17.1
7680
 0.22
chr8_66770156_66770307 0.17 PDE7A
 phosphodiesterase 7A
 16044
 0.27
chr6_143996619_143996770 0.17 PHACTR2
 phosphatase and actin regulator 2
 2408
 0.39
chr19_42744288_42744439 0.17 GSK3A
 glycogen synthase kinase 3 alpha
 1682
 0.17
chr9_123665604_123665920 0.17 TRAF1
 TNF receptor-associated factor 1
 11088
 0.19
chr7_43651721_43652066 0.17 STK17A
 serine/threonine kinase 17a
 29229
 0.15
chr5_172464440_172464591 0.17 ENSG00000207210
 .
 15043
 0.14
chr9_20640905_20641056 0.16 FOCAD
 focadhesin
 17328
 0.18
chr2_231279331_231279482 0.16 SP100
 SP100 nuclear antigen
 1251
 0.55
chr1_12674943_12675094 0.16 DHRS3
 dehydrogenase/reductase (SDR family) member 3
 2719
 0.25
chr9_130735456_130735638 0.16 FAM102A
 family with sequence similarity 102, member A
 7245
 0.11
chr3_13033156_13033307 0.16 IQSEC1
 IQ motif and Sec7 domain 1
 4695
 0.3
chr7_143002225_143002376 0.16 ENSG00000240322
 .
 6691
 0.1
chr17_8799606_8799757 0.16 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 14495
 0.2
chr6_33597995_33598146 0.16 ITPR3
 inositol 1,4,5-trisphosphate receptor, type 3
 8909
 0.14
chr2_106711761_106712080 0.16 C2orf40
 chromosome 2 open reading frame 40
 29664
 0.2
chr19_16708392_16708543 0.16 CTD-3222D19.5
9671
 0.09
chr21_34666749_34666900 0.15 IL10RB
 interleukin 10 receptor, beta
 28161
 0.12
chr3_108547468_108547619 0.15 TRAT1
 T cell receptor associated transmembrane adaptor 1
 5924
 0.28
chr9_138999698_138999849 0.15 C9orf69
 chromosome 9 open reading frame 69
 10347
 0.19
chr3_107694284_107694711 0.15 CD47
 CD47 molecule
 82711
 0.11
chr5_133382798_133382949 0.15 VDAC1
 voltage-dependent anion channel 1
 42049
 0.15
chr6_157119654_157119805 0.15 RP11-230C9.3
18140
 0.19
chr13_96743482_96743694 0.15 HS6ST3
 heparan sulfate 6-O-sulfotransferase 3
 495
 0.85
chr9_96327899_96328050 0.15 ENSG00000263875
 .
 108
 0.97
chr8_121783196_121783347 0.15 RP11-713M15.1
9778
 0.23
chr17_39496038_39496239 0.15 KRT33A
 keratin 33A
 10926
 0.08
chr2_179910796_179910947 0.15 CCDC141
 coiled-coil domain containing 141
 3915
 0.27
chr16_87876134_87876285 0.15 RP4-536B24.2
6071
 0.19
chr21_45359193_45359344 0.15 AGPAT3
 1-acylglycerol-3-phosphate O-acyltransferase 3
 7543
 0.18
chr3_9829316_9829467 0.15 ARPC4
 actin related protein 2/3 complex, subunit 4, 20kDa
 4788
 0.1
chr7_158571577_158571883 0.15 ESYT2
 extended synaptotagmin-like protein 2
 34822
 0.19
chr22_31502188_31502378 0.15 SELM
 Selenoprotein M
 1271
 0.3
chr5_86709837_86709988 0.15 CCNH
 cyclin H
 1076
 0.53
chr8_8197619_8197770 0.15 SGK223
 Tyrosine-protein kinase SgK223
 41563
 0.16
chr5_141821544_141821695 0.15 AC005592.2
37836
 0.19
chr14_22959333_22959484 0.15 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 3237
 0.13
chr10_75953508_75953715 0.15 ADK
 adenosine kinase
 17090
 0.22
chr15_70540546_70541057 0.15 ENSG00000200216
 .
 55226
 0.16
chr8_134494949_134495197 0.15 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 6226
 0.32
chr2_120595579_120595730 0.15 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
 77854
 0.1
chr10_8406671_8406822 0.15 ENSG00000212505
 .
 292048
 0.01
chr19_42426367_42426518 0.14 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 804
 0.52
chr5_176816529_176816680 0.14 SLC34A1
 solute carrier family 34 (type II sodium/phosphate contransporter), member 1
 5159
 0.1
chr6_42291647_42291798 0.14 ENSG00000221252
 .
 88412
 0.07
chr1_8467782_8467980 0.14 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 15845
 0.18
chr3_51312232_51312383 0.14 MANF
 mesencephalic astrocyte-derived neurotrophic factor
 110171
 0.06
chr10_3494380_3494531 0.14 PITRM1
 pitrilysin metallopeptidase 1
 279452
 0.01
chr13_114931895_114932090 0.14 RASA3
 RAS p21 protein activator 3
 33906
 0.16
chr4_148767939_148768090 0.14 ARHGAP10
 Rho GTPase activating protein 10
 35004
 0.16
chr3_16414400_16414551 0.14 RP11-415F23.4
27842
 0.17
chr15_63885452_63885603 0.14 USP3-AS1
 USP3 antisense RNA 1
 1376
 0.42
chr10_105189029_105189180 0.14 RP11-225H22.7
20849
 0.09
chr12_69285926_69286077 0.14 ENSG00000252770
 .
 19700
 0.15
chr11_125955059_125955210 0.14 CDON
 cell adhesion associated, oncogene regulated
 21904
 0.18
chr13_51170641_51170830 0.14 DLEU7-AS1
 DLEU7 antisense RNA 1
 211257
 0.02
chr10_112216760_112216911 0.14 ENSG00000264544
 .
 18517
 0.17
chr2_235337973_235338124 0.14 ARL4C
 ADP-ribosylation factor-like 4C
 67196
 0.14
chr7_129417298_129417546 0.14 ENSG00000207691
 .
 2568
 0.21
chr6_134595465_134595616 0.14 ENSG00000201309
 .
 8690
 0.19
chr22_47184851_47185002 0.14 TBC1D22A
 TBC1 domain family, member 22A
 15102
 0.19
chr17_7163807_7164082 0.14 CLDN7
 claudin 7
 520
 0.48
chr7_45958016_45958250 0.14 IGFBP3
 insulin-like growth factor binding protein 3
 1108
 0.52
chr1_36003475_36003698 0.14 KIAA0319L
 KIAA0319-like
 17002
 0.14
chr5_126406425_126406576 0.14 C5orf63
 chromosome 5 open reading frame 63
 815
 0.72
chr22_30692525_30692676 0.14 RP1-130H16.18
 Uncharacterized protein
 2871
 0.14
chr13_26480038_26480189 0.13 AL138815.2
 Uncharacterized protein
 27434
 0.16
chr10_12222611_12222762 0.13 NUDT5
 nudix (nucleoside diphosphate linked moiety X)-type motif 5
 15135
 0.12
chr4_48355584_48355735 0.13 SLAIN2
 SLAIN motif family, member 2
 12320
 0.25
chr2_175615864_175616015 0.13 CHRNA1
 cholinergic receptor, nicotinic, alpha 1 (muscle)
 13201
 0.24
chr5_14415059_14415274 0.13 TRIO
 trio Rho guanine nucleotide exchange factor
 73391
 0.12
chr12_103356683_103356834 0.13 PAH
 phenylalanine hydroxylase
 4614
 0.22
chr20_3783093_3783244 0.13 CDC25B
 cell division cycle 25B
 6090
 0.12
chr10_21785028_21785179 0.13 ENSG00000222071
 .
 467
 0.64
chr6_157194356_157194507 0.13 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 28076
 0.23
chr3_71532445_71532638 0.13 ENSG00000221264
 .
 58699
 0.13
chr1_167453393_167453610 0.13 RP11-104L21.2
25603
 0.17
chr3_128835970_128836121 0.13 RAB43
 RAB43, member RAS oncogene family
 4579
 0.14
chr14_100579946_100580097 0.13 ENSG00000199082
 .
 4029
 0.15
chr1_116929404_116929555 0.13 AL136376.1
 Uncharacterized protein
 2761
 0.21
chr18_51804642_51804943 0.13 POLI
 polymerase (DNA directed) iota
 4484
 0.25
chr1_214156856_214157007 0.13 PROX1
 prospero homeobox 1
 407
 0.85
chr11_61133550_61133701 0.13 TMEM138
 transmembrane protein 138
 450
 0.71
chr11_105886093_105886244 0.13 MSANTD4
 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
 6786
 0.2
chrX_117674478_117674629 0.13 ENSG00000206862
 .
 28925
 0.2
chr17_1081161_1081317 0.13 ABR
 active BCR-related
 1839
 0.34
chr17_2407698_2407849 0.13 METTL16
 methyltransferase like 16
 7407
 0.18
chr1_186258649_186258839 0.13 PRG4
 proteoglycan 4
 6661
 0.2
chr19_47947885_47948253 0.13 MEIS3
 Meis homeobox 3
 25289
 0.11
chr9_132393459_132393610 0.13 NTMT1
 N-terminal Xaa-Pro-Lys N-methyltransferase 1
 4811
 0.13
chr3_108553144_108553369 0.13 TRAT1
 T cell receptor associated transmembrane adaptor 1
 11637
 0.26
chr1_12530168_12530319 0.13 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 5248
 0.24
chr15_31642037_31642188 0.13 KLF13
 Kruppel-like factor 13
 9976
 0.3
chr2_240085793_240086170 0.13 AC017028.1
 Uncharacterized protein
 1928
 0.27
chr5_156473476_156473627 0.13 HAVCR1
 hepatitis A virus cellular receptor 1
 11856
 0.19
chr11_35353117_35353423 0.13 SLC1A2
 solute carrier family 1 (glial high affinity glutamate transporter), member 2
 30195
 0.17
chr16_58154872_58155238 0.12 CTB-134F13.1
4266
 0.14
chr15_31495377_31495528 0.12 TRPM1
 transient receptor potential cation channel, subfamily M, member 1
 41976
 0.18
chr1_94081045_94081360 0.12 BCAR3
 breast cancer anti-estrogen resistance 3
 1548
 0.43
chrX_40013584_40013785 0.12 BCOR
 BCL6 corepressor
 7802
 0.32
chr10_95460096_95460247 0.12 FRA10AC1
 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
 2154
 0.35
chr11_128381097_128381643 0.12 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 6081
 0.25
chr5_16673046_16673197 0.12 ENSG00000201370
 .
 49917
 0.12
chr7_48084885_48085036 0.12 C7orf57
 chromosome 7 open reading frame 57
 9843
 0.19
chr5_109280950_109281101 0.12 AC011366.3
 Uncharacterized protein
 62142
 0.16
chr14_89890480_89890631 0.12 FOXN3-AS1
 FOXN3 antisense RNA 1
 6857
 0.18
chr7_156795968_156796187 0.12 MNX1-AS2
 MNX1 antisense RNA 2
 2924
 0.22
chr12_56685183_56685363 0.12 CS
 citrate synthase
 8485
 0.07
chr6_91123599_91123783 0.12 ENSG00000252676
 .
 32800
 0.22
chr12_3563578_3563841 0.12 RP11-476M19.3
9043
 0.26
chr11_64088032_64088183 0.12 PRDX5
 peroxiredoxin 5
 2453
 0.1
chr5_109193615_109193766 0.12 AC011366.3
 Uncharacterized protein
 25193
 0.26
chr2_128391312_128391493 0.12 RP11-286H15.1
6979
 0.14
chr19_42396256_42396453 0.12 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 2011
 0.21
chr9_135036094_135036322 0.12 NTNG2
 netrin G2
 1126
 0.59
chr1_166815002_166815153 0.12 POGK
 pogo transposable element with KRAB domain
 5751
 0.25
chr11_59378018_59378169 0.12 OSBP
 oxysterol binding protein
 5524
 0.13
chr21_43744243_43744394 0.12 TFF3
 trefoil factor 3 (intestinal)
 8557
 0.14
chr6_112092329_112092498 0.12 FYN
 FYN oncogene related to SRC, FGR, YES
 9870
 0.28
chr6_159439729_159439953 0.12 RP1-111C20.4
7137
 0.19
chr4_109062726_109063018 0.12 LEF1
 lymphoid enhancer-binding factor 1
 24585
 0.2
chr16_89397725_89397876 0.12 ANKRD11
 ankyrin repeat domain 11
 2406
 0.21
chr7_150676591_150676887 0.12 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
 1336
 0.32
chr10_121160302_121160453 0.12 GRK5
 G protein-coupled receptor kinase 5
 22428
 0.18
chr2_159600251_159600402 0.12 AC005042.4
8812
 0.25
chr12_54440337_54440488 0.12 HOXC4
 homeobox C4
 7249
 0.08
chr12_92522877_92523028 0.12 C12orf79
 chromosome 12 open reading frame 79
 7845
 0.19
chr19_10520829_10520980 0.12 PDE4A
 phosphodiesterase 4A, cAMP-specific
 6545
 0.11
chr10_11324434_11324585 0.12 CELF2-AS1
 CELF2 antisense RNA 1
 37338
 0.2
chr6_170747344_170747495 0.12 RP1-140C12.2
24192
 0.21
chr1_186274017_186274168 0.12 ENSG00000202025
 .
 6968
 0.19
chr1_11415481_11415632 0.11 UBIAD1
 UbiA prenyltransferase domain containing 1
 81565
 0.08
chr19_16486076_16486459 0.11 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 13503
 0.14
chr5_96447388_96447539 0.11 CTD-2215E18.1
 Uncharacterized protein
 22684
 0.17
chr1_153941744_153941895 0.11 CREB3L4
 cAMP responsive element binding protein 3-like 4
 1033
 0.26
chr9_134153649_134153927 0.11 FAM78A
 family with sequence similarity 78, member A
 1854
 0.33
chr2_240169500_240169676 0.11 HDAC4
 histone deacetylase 4
 56836
 0.1
chr1_226848006_226848395 0.11 ITPKB-IT1
 ITPKB intronic transcript 1 (non-protein coding)
 829
 0.65
chr4_4297415_4297566 0.11 ZBTB49
 zinc finger and BTB domain containing 49
 5494
 0.19
chr7_128043233_128043384 0.11 IMPDH1
 IMP (inosine 5'-monophosphate) dehydrogenase 1
 2688
 0.21
chr14_98689187_98689819 0.11 ENSG00000222066
 .
 108584
 0.07
chr2_106722867_106723018 0.11 UXS1
 UDP-glucuronate decarboxylase 1
 32300
 0.18
chr16_89461717_89461868 0.11 RP1-168P16.2
17180
 0.13
chr2_24836758_24836909 0.11 NCOA1
 nuclear receptor coactivator 1
 29423
 0.18
chr1_117937222_117937373 0.11 MAN1A2
 mannosidase, alpha, class 1A, member 2
 25922
 0.25
chr17_8194100_8194251 0.11 RANGRF
 RAN guanine nucleotide release factor
 2179
 0.15
chrY_23267845_23267996 0.11 CYorf17
 chromosome Y open reading frame 17
 280326
 0.01
chr1_32294818_32294969 0.11 SPOCD1
 SPOC domain containing 1
 13241
 0.16
chr8_134300829_134300980 0.11 NDRG1
 N-myc downstream regulated 1
 7875
 0.26
chr12_115121082_115121268 0.11 TBX3
 T-box 3
 220
 0.95
chr2_84505605_84505756 0.11 SUCLG1
 succinate-CoA ligase, alpha subunit
 180924
 0.03
chr3_149375939_149376119 0.11 WWTR1-AS1
 WWTR1 antisense RNA 1
 32
 0.63

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of TCF7L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0072193 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0051136 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0060068 vagina development(GO:0060068)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.0 0.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.0 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.0 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0061054 dermatome development(GO:0061054)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation