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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for TCF7L1

Z-value: 0.93

Motif logo

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Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
TCF7L1
ENSG00000152284.4 transcription factor 7 like 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr2_85284511_85284681TCF7L1759370.0843330.771.6e-02Click!
chr2_85282591_85282742TCF7L1778670.081553-0.608.9e-02Click!
chr2_85284961_85285173TCF7L1754660.0850250.561.2e-01Click!
chr2_85359450_85359601TCF7L110080.5802870.551.2e-01Click!
chr2_85280075_85280226TCF7L1803830.0780640.462.1e-01Click!

Activity of the TCF7L1 motif across conditions

Conditions sorted by the z-value of the TCF7L1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_49946029_49946413 0.31 CAB39L
 calcium binding protein 39-like
 5046
 0.26
chr17_38182542_38182693 0.30 ENSG00000238793
 .
 1281
 0.3
chr14_68648383_68648543 0.29 ENSG00000244677
 .
 31838
 0.18
chr16_50651385_50651565 0.27 RP11-401P9.6
3880
 0.2
chr8_128840086_128840237 0.25 ENSG00000249859
 .
 31953
 0.2
chr2_109580892_109581113 0.24 EDAR
 ectodysplasin A receptor
 24723
 0.24
chr5_156319485_156319636 0.24 TIMD4
 T-cell immunoglobulin and mucin domain containing 4
 43127
 0.17
chr11_130259035_130259186 0.24 ADAMTS8
 ADAM metallopeptidase with thrombospondin type 1 motif, 8
 39778
 0.16
chr5_76625160_76625430 0.23 PDE8B
 phosphodiesterase 8B
 3777
 0.34
chr11_57449245_57449396 0.22 ZDHHC5
 zinc finger, DHHC-type containing 5
 692
 0.53
chr3_49025329_49025480 0.22 P4HTM
 prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
 1915
 0.14
chr12_65094836_65094987 0.22 AC025262.1
 Mesenchymal stem cell protein DSC96; Uncharacterized protein
 4582
 0.17
chr4_4227781_4227932 0.22 OTOP1
 otopetrin 1
 760
 0.67
chr10_73862702_73862853 0.22 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 13987
 0.21
chr4_981402_981614 0.22 IDUA
 iduronidase, alpha-L-
 633
 0.46
chr1_207073979_207074130 0.22 IL24
 interleukin 24
 2876
 0.21
chr19_33662270_33662421 0.22 ENSG00000264355
 .
 5633
 0.14
chr9_98620223_98620374 0.22 ENSG00000252847
 .
 1888
 0.36
chr7_100814110_100814261 0.22 VGF
 VGF nerve growth factor inducible
 5311
 0.1
chr13_22681618_22681904 0.22 ENSG00000244197
 .
 317085
 0.01
chr14_65237977_65238128 0.21 SPTB
 spectrin, beta, erythrocytic
 11216
 0.2
chr18_67070231_67070382 0.21 DOK6
 docking protein 6
 2015
 0.5
chr17_1776866_1777017 0.21 RPA1
 replication protein A1, 70kDa
 5388
 0.17
chr2_235056234_235056385 0.21 SPP2
 secreted phosphoprotein 2, 24kDa
 96878
 0.08
chr15_87160145_87160540 0.21 RP11-182L7.1
14025
 0.31
chr16_1018736_1018887 0.21 LMF1
 lipase maturation factor 1
 2055
 0.21
chr12_124416244_124416395 0.20 DNAH10OS
 dynein, axonemal, heavy chain 10 opposite strand
 3212
 0.11
chr16_3064160_3064311 0.20 CLDN9
 claudin 9
 1778
 0.12
chr7_27278726_27278948 0.20 EVX1
 even-skipped homeobox 1
 3327
 0.13
chr13_30532983_30533134 0.20 LINC00572
 long intergenic non-protein coding RNA 572
 32270
 0.23
chr11_62285356_62285507 0.20 AHNAK
 AHNAK nucleoprotein
 18148
 0.09
chr7_537977_538128 0.19 PDGFA
 platelet-derived growth factor alpha polypeptide
 20093
 0.2
chr8_19250899_19251050 0.19 SH2D4A
 SH2 domain containing 4A
 73873
 0.13
chr2_99527888_99528039 0.19 KIAA1211L
 KIAA1211-like
 2979
 0.33
chr1_111212908_111213059 0.19 KCNA3
 potassium voltage-gated channel, shaker-related subfamily, member 3
 4672
 0.21
chr5_80400951_80401102 0.19 CTD-2193P3.2
9645
 0.28
chr1_46808965_46809116 0.19 NSUN4
 NOP2/Sun domain family, member 4
 2164
 0.27
chr7_141211304_141211601 0.18 AGK
 acylglycerol kinase
 39537
 0.14
chr16_69200425_69200916 0.18 ENSG00000207083
 .
 9010
 0.12
chr11_13317651_13317839 0.18 ARNTL
 aryl hydrocarbon receptor nuclear translocator-like
 13788
 0.26
chr2_25498362_25498513 0.18 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
 23257
 0.19
chr1_93042440_93042924 0.18 GFI1
 growth factor independent 1 transcription repressor
 90249
 0.08
chr1_168482288_168482558 0.18 XCL2
 chemokine (C motif) ligand 2
 30812
 0.2
chr7_157619868_157620019 0.18 AC011899.9
27278
 0.2
chr21_34557928_34558079 0.17 C21orf54
 chromosome 21 open reading frame 54
 15462
 0.15
chr10_105564418_105564569 0.17 SH3PXD2A
 SH3 and PX domains 2A
 3438
 0.29
chr20_415273_415424 0.17 ENSG00000206797
 .
 15959
 0.14
chr6_111908214_111908423 0.17 TRAF3IP2-AS1
 TRAF3IP2 antisense RNA 1
 12496
 0.17
chr2_237283808_237283959 0.17 RP11-785G17.1
7680
 0.22
chr8_66770156_66770307 0.17 PDE7A
 phosphodiesterase 7A
 16044
 0.27
chr6_143996619_143996770 0.17 PHACTR2
 phosphatase and actin regulator 2
 2408
 0.39
chr19_42744288_42744439 0.17 GSK3A
 glycogen synthase kinase 3 alpha
 1682
 0.17
chr9_123665604_123665920 0.17 TRAF1
 TNF receptor-associated factor 1
 11088
 0.19
chr7_43651721_43652066 0.17 STK17A
 serine/threonine kinase 17a
 29229
 0.15
chr5_172464440_172464591 0.17 ENSG00000207210
 .
 15043
 0.14
chr9_20640905_20641056 0.16 FOCAD
 focadhesin
 17328
 0.18
chr2_231279331_231279482 0.16 SP100
 SP100 nuclear antigen
 1251
 0.55
chr1_12674943_12675094 0.16 DHRS3
 dehydrogenase/reductase (SDR family) member 3
 2719
 0.25
chr9_130735456_130735638 0.16 FAM102A
 family with sequence similarity 102, member A
 7245
 0.11
chr3_13033156_13033307 0.16 IQSEC1
 IQ motif and Sec7 domain 1
 4695
 0.3
chr7_143002225_143002376 0.16 ENSG00000240322
 .
 6691
 0.1
chr17_8799606_8799757 0.16 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 14495
 0.2
chr6_33597995_33598146 0.16 ITPR3
 inositol 1,4,5-trisphosphate receptor, type 3
 8909
 0.14
chr2_106711761_106712080 0.16 C2orf40
 chromosome 2 open reading frame 40
 29664
 0.2
chr19_16708392_16708543 0.16 CTD-3222D19.5
9671
 0.09
chr21_34666749_34666900 0.15 IL10RB
 interleukin 10 receptor, beta
 28161
 0.12
chr3_108547468_108547619 0.15 TRAT1
 T cell receptor associated transmembrane adaptor 1
 5924
 0.28
chr9_138999698_138999849 0.15 C9orf69
 chromosome 9 open reading frame 69
 10347
 0.19
chr3_107694284_107694711 0.15 CD47
 CD47 molecule
 82711
 0.11
chr5_133382798_133382949 0.15 VDAC1
 voltage-dependent anion channel 1
 42049
 0.15
chr6_157119654_157119805 0.15 RP11-230C9.3
18140
 0.19
chr13_96743482_96743694 0.15 HS6ST3
 heparan sulfate 6-O-sulfotransferase 3
 495
 0.85
chr9_96327899_96328050 0.15 ENSG00000263875
 .
 108
 0.97
chr8_121783196_121783347 0.15 RP11-713M15.1
9778
 0.23
chr17_39496038_39496239 0.15 KRT33A
 keratin 33A
 10926
 0.08
chr2_179910796_179910947 0.15 CCDC141
 coiled-coil domain containing 141
 3915
 0.27
chr16_87876134_87876285 0.15 RP4-536B24.2
6071
 0.19
chr21_45359193_45359344 0.15 AGPAT3
 1-acylglycerol-3-phosphate O-acyltransferase 3
 7543
 0.18
chr3_9829316_9829467 0.15 ARPC4
 actin related protein 2/3 complex, subunit 4, 20kDa
 4788
 0.1
chr7_158571577_158571883 0.15 ESYT2
 extended synaptotagmin-like protein 2
 34822
 0.19
chr22_31502188_31502378 0.15 SELM
 Selenoprotein M
 1271
 0.3
chr5_86709837_86709988 0.15 CCNH
 cyclin H
 1076
 0.53
chr8_8197619_8197770 0.15 SGK223
 Tyrosine-protein kinase SgK223
 41563
 0.16
chr5_141821544_141821695 0.15 AC005592.2
37836
 0.19
chr14_22959333_22959484 0.15 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 3237
 0.13
chr10_75953508_75953715 0.15 ADK
 adenosine kinase
 17090
 0.22
chr15_70540546_70541057 0.15 ENSG00000200216
 .
 55226
 0.16
chr8_134494949_134495197 0.15 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 6226
 0.32
chr2_120595579_120595730 0.15 PTPN4
 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
 77854
 0.1
chr10_8406671_8406822 0.15 ENSG00000212505
 .
 292048
 0.01
chr19_42426367_42426518 0.14 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 804
 0.52
chr5_176816529_176816680 0.14 SLC34A1
 solute carrier family 34 (type II sodium/phosphate contransporter), member 1
 5159
 0.1
chr6_42291647_42291798 0.14 ENSG00000221252
 .
 88412
 0.07
chr1_8467782_8467980 0.14 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 15845
 0.18
chr3_51312232_51312383 0.14 MANF
 mesencephalic astrocyte-derived neurotrophic factor
 110171
 0.06
chr10_3494380_3494531 0.14 PITRM1
 pitrilysin metallopeptidase 1
 279452
 0.01
chr13_114931895_114932090 0.14 RASA3
 RAS p21 protein activator 3
 33906
 0.16
chr4_148767939_148768090 0.14 ARHGAP10
 Rho GTPase activating protein 10
 35004
 0.16
chr3_16414400_16414551 0.14 RP11-415F23.4
27842
 0.17
chr15_63885452_63885603 0.14 USP3-AS1
 USP3 antisense RNA 1
 1376
 0.42
chr10_105189029_105189180 0.14 RP11-225H22.7
20849
 0.09
chr12_69285926_69286077 0.14 ENSG00000252770
 .
 19700
 0.15
chr11_125955059_125955210 0.14 CDON
 cell adhesion associated, oncogene regulated
 21904
 0.18
chr13_51170641_51170830 0.14 DLEU7-AS1
 DLEU7 antisense RNA 1
 211257
 0.02
chr10_112216760_112216911 0.14 ENSG00000264544
 .
 18517
 0.17
chr2_235337973_235338124 0.14 ARL4C
 ADP-ribosylation factor-like 4C
 67196
 0.14
chr7_129417298_129417546 0.14 ENSG00000207691
 .
 2568
 0.21
chr6_134595465_134595616 0.14 ENSG00000201309
 .
 8690
 0.19
chr22_47184851_47185002 0.14 TBC1D22A
 TBC1 domain family, member 22A
 15102
 0.19
chr17_7163807_7164082 0.14 CLDN7
 claudin 7
 520
 0.48
chr7_45958016_45958250 0.14 IGFBP3
 insulin-like growth factor binding protein 3
 1108
 0.52
chr1_36003475_36003698 0.14 KIAA0319L
 KIAA0319-like
 17002
 0.14
chr5_126406425_126406576 0.14 C5orf63
 chromosome 5 open reading frame 63
 815
 0.72
chr22_30692525_30692676 0.14 RP1-130H16.18
 Uncharacterized protein
 2871
 0.14
chr13_26480038_26480189 0.13 AL138815.2
 Uncharacterized protein
 27434
 0.16
chr10_12222611_12222762 0.13 NUDT5
 nudix (nucleoside diphosphate linked moiety X)-type motif 5
 15135
 0.12
chr4_48355584_48355735 0.13 SLAIN2
 SLAIN motif family, member 2
 12320
 0.25
chr2_175615864_175616015 0.13 CHRNA1
 cholinergic receptor, nicotinic, alpha 1 (muscle)
 13201
 0.24
chr5_14415059_14415274 0.13 TRIO
 trio Rho guanine nucleotide exchange factor
 73391
 0.12
chr12_103356683_103356834 0.13 PAH
 phenylalanine hydroxylase
 4614
 0.22
chr20_3783093_3783244 0.13 CDC25B
 cell division cycle 25B
 6090
 0.12
chr10_21785028_21785179 0.13 ENSG00000222071
 .
 467
 0.64
chr6_157194356_157194507 0.13 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 28076
 0.23
chr3_71532445_71532638 0.13 ENSG00000221264
 .
 58699
 0.13
chr1_167453393_167453610 0.13 RP11-104L21.2
25603
 0.17
chr3_128835970_128836121 0.13 RAB43
 RAB43, member RAS oncogene family
 4579
 0.14
chr14_100579946_100580097 0.13 ENSG00000199082
 .
 4029
 0.15
chr1_116929404_116929555 0.13 AL136376.1
 Uncharacterized protein
 2761
 0.21
chr18_51804642_51804943 0.13 POLI
 polymerase (DNA directed) iota
 4484
 0.25
chr1_214156856_214157007 0.13 PROX1
 prospero homeobox 1
 407
 0.85
chr11_61133550_61133701 0.13 TMEM138
 transmembrane protein 138
 450
 0.71
chr11_105886093_105886244 0.13 MSANTD4
 Myb/SANT-like DNA-binding domain containing 4 with coiled-coils
 6786
 0.2
chrX_117674478_117674629 0.13 ENSG00000206862
 .
 28925
 0.2
chr17_1081161_1081317 0.13 ABR
 active BCR-related
 1839
 0.34
chr17_2407698_2407849 0.13 METTL16
 methyltransferase like 16
 7407
 0.18
chr1_186258649_186258839 0.13 PRG4
 proteoglycan 4
 6661
 0.2
chr19_47947885_47948253 0.13 MEIS3
 Meis homeobox 3
 25289
 0.11
chr9_132393459_132393610 0.13 NTMT1
 N-terminal Xaa-Pro-Lys N-methyltransferase 1
 4811
 0.13
chr3_108553144_108553369 0.13 TRAT1
 T cell receptor associated transmembrane adaptor 1
 11637
 0.26
chr1_12530168_12530319 0.13 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 5248
 0.24
chr15_31642037_31642188 0.13 KLF13
 Kruppel-like factor 13
 9976
 0.3
chr2_240085793_240086170 0.13 AC017028.1
 Uncharacterized protein
 1928
 0.27
chr5_156473476_156473627 0.13 HAVCR1
 hepatitis A virus cellular receptor 1
 11856
 0.19
chr11_35353117_35353423 0.13 SLC1A2
 solute carrier family 1 (glial high affinity glutamate transporter), member 2
 30195
 0.17
chr16_58154872_58155238 0.12 CTB-134F13.1
4266
 0.14
chr15_31495377_31495528 0.12 TRPM1
 transient receptor potential cation channel, subfamily M, member 1
 41976
 0.18
chr1_94081045_94081360 0.12 BCAR3
 breast cancer anti-estrogen resistance 3
 1548
 0.43
chrX_40013584_40013785 0.12 BCOR
 BCL6 corepressor
 7802
 0.32
chr10_95460096_95460247 0.12 FRA10AC1
 fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
 2154
 0.35
chr11_128381097_128381643 0.12 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 6081
 0.25
chr5_16673046_16673197 0.12 ENSG00000201370
 .
 49917
 0.12
chr7_48084885_48085036 0.12 C7orf57
 chromosome 7 open reading frame 57
 9843
 0.19
chr5_109280950_109281101 0.12 AC011366.3
 Uncharacterized protein
 62142
 0.16
chr14_89890480_89890631 0.12 FOXN3-AS1
 FOXN3 antisense RNA 1
 6857
 0.18
chr7_156795968_156796187 0.12 MNX1-AS2
 MNX1 antisense RNA 2
 2924
 0.22
chr12_56685183_56685363 0.12 CS
 citrate synthase
 8485
 0.07
chr6_91123599_91123783 0.12 ENSG00000252676
 .
 32800
 0.22
chr12_3563578_3563841 0.12 RP11-476M19.3
9043
 0.26
chr11_64088032_64088183 0.12 PRDX5
 peroxiredoxin 5
 2453
 0.1
chr5_109193615_109193766 0.12 AC011366.3
 Uncharacterized protein
 25193
 0.26
chr2_128391312_128391493 0.12 RP11-286H15.1
6979
 0.14
chr19_42396256_42396453 0.12 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 2011
 0.21
chr9_135036094_135036322 0.12 NTNG2
 netrin G2
 1126
 0.59
chr1_166815002_166815153 0.12 POGK
 pogo transposable element with KRAB domain
 5751
 0.25
chr11_59378018_59378169 0.12 OSBP
 oxysterol binding protein
 5524
 0.13
chr21_43744243_43744394 0.12 TFF3
 trefoil factor 3 (intestinal)
 8557
 0.14
chr6_112092329_112092498 0.12 FYN
 FYN oncogene related to SRC, FGR, YES
 9870
 0.28
chr6_159439729_159439953 0.12 RP1-111C20.4
7137
 0.19
chr4_109062726_109063018 0.12 LEF1
 lymphoid enhancer-binding factor 1
 24585
 0.2
chr16_89397725_89397876 0.12 ANKRD11
 ankyrin repeat domain 11
 2406
 0.21
chr7_150676591_150676887 0.12 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
 1336
 0.32
chr10_121160302_121160453 0.12 GRK5
 G protein-coupled receptor kinase 5
 22428
 0.18
chr2_159600251_159600402 0.12 AC005042.4
8812
 0.25
chr12_54440337_54440488 0.12 HOXC4
 homeobox C4
 7249
 0.08
chr12_92522877_92523028 0.12 C12orf79
 chromosome 12 open reading frame 79
 7845
 0.19
chr19_10520829_10520980 0.12 PDE4A
 phosphodiesterase 4A, cAMP-specific
 6545
 0.11
chr10_11324434_11324585 0.12 CELF2-AS1
 CELF2 antisense RNA 1
 37338
 0.2
chr6_170747344_170747495 0.12 RP1-140C12.2
24192
 0.21
chr1_186274017_186274168 0.12 ENSG00000202025
 .
 6968
 0.19
chr1_11415481_11415632 0.11 UBIAD1
 UbiA prenyltransferase domain containing 1
 81565
 0.08
chr19_16486076_16486459 0.11 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 13503
 0.14
chr5_96447388_96447539 0.11 CTD-2215E18.1
 Uncharacterized protein
 22684
 0.17
chr1_153941744_153941895 0.11 CREB3L4
 cAMP responsive element binding protein 3-like 4
 1033
 0.26
chr9_134153649_134153927 0.11 FAM78A
 family with sequence similarity 78, member A
 1854
 0.33
chr2_240169500_240169676 0.11 HDAC4
 histone deacetylase 4
 56836
 0.1
chr1_226848006_226848395 0.11 ITPKB-IT1
 ITPKB intronic transcript 1 (non-protein coding)
 829
 0.65
chr4_4297415_4297566 0.11 ZBTB49
 zinc finger and BTB domain containing 49
 5494
 0.19
chr7_128043233_128043384 0.11 IMPDH1
 IMP (inosine 5'-monophosphate) dehydrogenase 1
 2688
 0.21
chr14_98689187_98689819 0.11 ENSG00000222066
 .
 108584
 0.07
chr2_106722867_106723018 0.11 UXS1
 UDP-glucuronate decarboxylase 1
 32300
 0.18
chr16_89461717_89461868 0.11 RP1-168P16.2
17180
 0.13
chr2_24836758_24836909 0.11 NCOA1
 nuclear receptor coactivator 1
 29423
 0.18
chr1_117937222_117937373 0.11 MAN1A2
 mannosidase, alpha, class 1A, member 2
 25922
 0.25
chr17_8194100_8194251 0.11 RANGRF
 RAN guanine nucleotide release factor
 2179
 0.15
chrY_23267845_23267996 0.11 CYorf17
 chromosome Y open reading frame 17
 280326
 0.01
chr1_32294818_32294969 0.11 SPOCD1
 SPOC domain containing 1
 13241
 0.16
chr8_134300829_134300980 0.11 NDRG1
 N-myc downstream regulated 1
 7875
 0.26
chr12_115121082_115121268 0.11 TBX3
 T-box 3
 220
 0.95
chr2_84505605_84505756 0.11 SUCLG1
 succinate-CoA ligase, alpha subunit
 180924
 0.03
chr3_149375939_149376119 0.11 WWTR1-AS1
 WWTR1 antisense RNA 1
 32
 0.63

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0030812 negative regulation of nucleotide catabolic process(GO:0030812)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0072193 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0051136 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0060068 vagina development(GO:0060068)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.0 0.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.0 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.0 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.0 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0061054 dermatome development(GO:0061054)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation