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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TCF7L2

Z-value: 1.60

Motif logo

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Transcription factors associated with TCF7L2

Gene Symbol Gene ID Gene Info
ENSG00000148737.11 TCF7L2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
TCF7L2chr10_114891572_114891723120320.297123-0.835.4e-03Click!
TCF7L2chr10_114859684_114859835439200.194701-0.817.9e-03Click!
TCF7L2chr10_114880713_114880925228600.264918-0.818.0e-03Click!
TCF7L2chr10_114847017_114847168565870.156617-0.791.1e-02Click!
TCF7L2chr10_114859297_114859448443070.193450-0.761.8e-02Click!

Activity of the TCF7L2 motif across conditions

Conditions sorted by the z-value of the TCF7L2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr16_30392632_30392982 0.81 SEPT1
septin 1
945
0.31
chr12_69285926_69286077 0.77 ENSG00000252770
.
19700
0.15
chr1_111185398_111185573 0.77 ENSG00000221538
.
10168
0.17
chr1_227949174_227949396 0.76 SNAP47
synaptosomal-associated protein, 47kDa
13521
0.16
chr6_130543838_130543989 0.75 SAMD3
sterile alpha motif domain containing 3
45
0.99
chr7_100814110_100814261 0.75 VGF
VGF nerve growth factor inducible
5311
0.1
chr12_21766078_21766229 0.74 GYS2
glycogen synthase 2 (liver)
8372
0.2
chr17_8799606_8799757 0.71 PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
14495
0.2
chr13_22681618_22681904 0.68 ENSG00000244197
.
317085
0.01
chr19_47947885_47948253 0.68 MEIS3
Meis homeobox 3
25289
0.11
chr1_168482288_168482558 0.67 XCL2
chemokine (C motif) ligand 2
30812
0.2
chr21_40581899_40582053 0.65 BRWD1-IT1
BRWD1 intronic transcript 1 (non-protein coding)
9755
0.16
chr1_110038713_110038864 0.64 CYB561D1
cytochrome b561 family, member D1
2051
0.19
chr3_31506056_31506507 0.62 STT3B
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
68001
0.12
chr2_175615864_175616015 0.62 CHRNA1
cholinergic receptor, nicotinic, alpha 1 (muscle)
13201
0.24
chr19_10254387_10254800 0.61 EIF3G
eukaryotic translation initiation factor 3, subunit G
24015
0.07
chr10_6555265_6555571 0.59 PRKCQ
protein kinase C, theta
66783
0.13
chr14_65237977_65238128 0.59 SPTB
spectrin, beta, erythrocytic
11216
0.2
chr10_85439569_85439720 0.59 ENSG00000212324
.
84470
0.11
chrX_99667126_99667277 0.58 PCDH19
protocadherin 19
1930
0.48
chr8_133990678_133991177 0.58 TG
thyroglobulin
14075
0.25
chr14_22959333_22959484 0.57 TRAJ51
T cell receptor alpha joining 51 (pseudogene)
3237
0.13
chr1_145822570_145822721 0.56 GPR89A
G protein-coupled receptor 89A
3805
0.2
chr6_28416917_28417068 0.55 ZSCAN23
zinc finger and SCAN domain containing 23
5748
0.18
chr11_130259035_130259186 0.55 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
39778
0.16
chr15_73434482_73434633 0.54 NEO1
neogenin 1
6231
0.3
chr15_61092642_61092831 0.53 RP11-554D20.1

35797
0.19
chr15_26092284_26092435 0.53 ENSG00000266517
.
1613
0.38
chr13_95159605_95159756 0.52 DCT
dopachrome tautomerase
27744
0.19
chr18_67070231_67070382 0.52 DOK6
docking protein 6
2015
0.5
chr9_130198891_130199042 0.52 ENSG00000201302
.
11943
0.12
chr21_34666749_34666900 0.52 IL10RB
interleukin 10 receptor, beta
28161
0.12
chr2_234337014_234337165 0.52 DGKD
diacylglycerol kinase, delta 130kDa
40289
0.12
chr11_35353117_35353423 0.52 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
30195
0.17
chr14_72984789_72985172 0.52 RGS6
regulator of G-protein signaling 6
58603
0.16
chr15_87160145_87160540 0.51 RP11-182L7.1

14025
0.31
chr16_78600613_78600816 0.51 RP11-264L1.3

32443
0.22
chr3_18765552_18765703 0.51 ENSG00000228956
.
21609
0.29
chr5_75625266_75625417 0.50 RP11-466P24.6

18054
0.26
chr13_49946029_49946413 0.50 CAB39L
calcium binding protein 39-like
5046
0.26
chr3_136618635_136619053 0.49 NCK1
NCK adaptor protein 1
28037
0.15
chr4_109062726_109063018 0.49 LEF1
lymphoid enhancer-binding factor 1
24585
0.2
chr14_90086637_90086896 0.49 FOXN3
forkhead box N3
1273
0.31
chr4_143632176_143632327 0.49 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
135192
0.06
chr17_34040072_34040441 0.49 RASL10B
RAS-like, family 10, member B
18412
0.11
chr1_100908166_100908711 0.49 RP5-837M10.4

43115
0.14
chr2_158287576_158287811 0.48 CYTIP
cytohesin 1 interacting protein
8233
0.23
chr17_53421254_53421405 0.48 RP11-515O17.2

70315
0.11
chr1_198621914_198622156 0.48 PTPRC
protein tyrosine phosphatase, receptor type, C
13743
0.23
chr8_37131917_37132068 0.48 RP11-150O12.6

242547
0.02
chr16_87876134_87876285 0.48 RP4-536B24.2

6071
0.19
chr1_111441973_111442124 0.48 CD53
CD53 molecule
26272
0.14
chr2_196455529_196455680 0.48 SLC39A10
solute carrier family 39 (zinc transporter), member 10
14903
0.26
chr10_48439625_48439776 0.48 GDF10
growth differentiation factor 10
724
0.66
chr18_51612590_51612843 0.48 ENSG00000221058
.
310
0.94
chr2_84505605_84505756 0.48 SUCLG1
succinate-CoA ligase, alpha subunit
180924
0.03
chr3_16977379_16977634 0.47 ENSG00000264818
.
2818
0.29
chr11_128215789_128216020 0.47 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
159385
0.04
chr6_157119654_157119805 0.47 RP11-230C9.3

18140
0.19
chr1_207633000_207633151 0.46 CR2
complement component (3d/Epstein Barr virus) receptor 2
5365
0.23
chr3_16414400_16414551 0.46 RP11-415F23.4

27842
0.17
chr1_226858842_226859047 0.46 ITPKB-AS1
ITPKB antisense RNA 1
2346
0.3
chr18_19173663_19173867 0.46 ESCO1
establishment of sister chromatid cohesion N-acetyltransferase 1
6932
0.16
chr5_172464440_172464591 0.46 ENSG00000207210
.
15043
0.14
chr10_73839065_73839273 0.46 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
8917
0.24
chr22_22121909_22122114 0.45 ENSG00000200985
.
24712
0.12
chr17_17759123_17759274 0.45 TOM1L2
target of myb1-like 2 (chicken)
6896
0.16
chr4_122110306_122110568 0.45 ENSG00000252183
.
3621
0.28
chr15_31495377_31495528 0.45 TRPM1
transient receptor potential cation channel, subfamily M, member 1
41976
0.18
chr9_123665604_123665920 0.45 TRAF1
TNF receptor-associated factor 1
11088
0.19
chr1_173487659_173487906 0.45 RP3-436N22.3

36608
0.14
chr1_167441502_167441653 0.45 RP11-104L21.2

13679
0.2
chr13_40929307_40929458 0.44 ENSG00000252812
.
52195
0.17
chr22_40675474_40675625 0.44 TNRC6B
trinucleotide repeat containing 6B
14542
0.22
chr5_80400951_80401102 0.44 CTD-2193P3.2

9645
0.28
chr5_174949747_174950007 0.44 SFXN1
sideroflexin 1
44282
0.15
chr10_48532058_48532297 0.44 GDF10
growth differentiation factor 10
93201
0.07
chr9_117752150_117752475 0.44 TNFSF8
tumor necrosis factor (ligand) superfamily, member 8
59615
0.13
chr8_135538581_135538732 0.44 ZFAT
zinc finger and AT hook domain containing
16231
0.28
chr17_25943487_25943638 0.44 KSR1
kinase suppressor of ras 1
4499
0.19
chr1_172733190_172733341 0.44 FASLG
Fas ligand (TNF superfamily, member 6)
105107
0.07
chr16_50651385_50651565 0.44 RP11-401P9.6

3880
0.2
chr14_89790943_89791116 0.43 RP11-356K23.1

25600
0.17
chr1_213182486_213182660 0.43 ANGEL2
angel homolog 2 (Drosophila)
6247
0.24
chr11_59378018_59378169 0.43 OSBP
oxysterol binding protein
5524
0.13
chr10_6555656_6555821 0.43 PRKCQ
protein kinase C, theta
66463
0.14
chr6_11375208_11375428 0.42 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
7214
0.29
chr1_236579990_236580147 0.42 EDARADD
EDAR-associated death domain
21352
0.21
chr7_143899062_143899275 0.42 RP4-545C24.1

5615
0.12
chr1_39030101_39030252 0.42 ENSG00000200796
.
167845
0.03
chr6_52078155_52078306 0.42 IL17A
interleukin 17A
27045
0.15
chr12_21832774_21832934 0.42 RP11-59N23.3

17607
0.18
chr11_120950309_120950460 0.42 TECTA
tectorin alpha
21498
0.23
chr1_160676517_160676733 0.42 CD48
CD48 molecule
4968
0.18
chr3_71144052_71144203 0.41 FOXP1
forkhead box P1
29209
0.25
chr6_27122996_27123197 0.41 ENSG00000265565
.
7691
0.12
chr2_106386688_106386930 0.41 NCK2
NCK adaptor protein 2
24621
0.25
chrX_135064888_135065039 0.41 SLC9A6
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
2635
0.27
chr20_415273_415424 0.41 ENSG00000206797
.
15959
0.14
chr22_38022512_38022663 0.41 GGA1
golgi-associated, gamma adaptin ear containing, ARF binding protein 1
12447
0.1
chr5_35784561_35784712 0.41 SPEF2
sperm flagellar 2
5366
0.25
chr6_5832810_5832961 0.41 ENSG00000239472
.
86192
0.1
chr5_138633328_138633510 0.41 ENSG00000199545
.
2122
0.18
chr17_45962930_45963230 0.41 SP2
Sp2 transcription factor
10436
0.1
chr4_48355584_48355735 0.40 SLAIN2
SLAIN motif family, member 2
12320
0.25
chr3_128835970_128836121 0.40 RAB43
RAB43, member RAS oncogene family
4579
0.14
chr4_99447171_99447322 0.40 RP11-724M22.1

29731
0.23
chr7_143002225_143002376 0.40 ENSG00000240322
.
6691
0.1
chr1_116933196_116933468 0.40 AL136376.1
Uncharacterized protein
6614
0.16
chr7_158571577_158571883 0.40 ESYT2
extended synaptotagmin-like protein 2
34822
0.19
chr12_65094836_65094987 0.40 AC025262.1
Mesenchymal stem cell protein DSC96; Uncharacterized protein
4582
0.17
chr4_101962045_101962196 0.40 EMCN-IT1
EMCN intronic transcript 1 (non-protein coding)
226683
0.02
chr13_52527464_52527703 0.40 ATP7B
ATPase, Cu++ transporting, beta polypeptide
8468
0.22
chr8_66770156_66770307 0.40 PDE7A
phosphodiesterase 7A
16044
0.27
chr5_75768199_75768431 0.40 IQGAP2
IQ motif containing GTPase activating protein 2
68066
0.12
chr1_207073979_207074130 0.40 IL24
interleukin 24
2876
0.21
chr5_86709837_86709988 0.40 CCNH
cyclin H
1076
0.53
chr7_110652057_110652271 0.39 LRRN3
leucine rich repeat neuronal 3
78898
0.1
chr10_126363567_126363777 0.39 FAM53B-AS1
FAM53B antisense RNA 1
28522
0.18
chrX_109233817_109234346 0.39 TMEM164
transmembrane protein 164
11782
0.26
chr4_114821736_114822076 0.39 RP11-26P13.2

42506
0.19
chr16_79313853_79314004 0.39 ENSG00000222244
.
15577
0.29
chr1_239973629_239973780 0.39 ENSG00000233355
.
79939
0.1
chr14_52353861_52354066 0.39 GNG2
guanine nucleotide binding protein (G protein), gamma 2
9653
0.19
chr14_91784767_91784985 0.39 ENSG00000265856
.
15181
0.19
chr7_33117172_33117364 0.39 NT5C3A
5'-nucleotidase, cytosolic IIIA
14859
0.14
chr11_114044678_114044829 0.39 NNMT
nicotinamide N-methyltransferase
83800
0.08
chr3_107403327_107403720 0.39 BBX
bobby sox homolog (Drosophila)
9871
0.32
chr19_15257331_15257482 0.38 ENSG00000252661
.
1380
0.31
chr17_63429770_63429921 0.38 ENSG00000265189
.
13067
0.29
chr4_40308291_40308829 0.38 CHRNA9
cholinergic receptor, nicotinic, alpha 9 (neuronal)
28786
0.18
chr6_13686993_13687323 0.38 RANBP9
RAN binding protein 9
22
0.98
chr6_142470789_142470940 0.38 VTA1
vesicle (multivesicular body) trafficking 1
2466
0.3
chr9_15191492_15191643 0.38 TTC39B
tetratricopeptide repeat domain 39B
40875
0.17
chr5_141821544_141821695 0.38 AC005592.2

37836
0.19
chr2_235371267_235371613 0.38 ARL4C
ADP-ribosylation factor-like 4C
33804
0.25
chr16_11669510_11669762 0.38 LITAF
lipopolysaccharide-induced TNF factor
10593
0.19
chr12_4082991_4083686 0.38 RP11-664D1.1

68952
0.12
chr19_55010533_55010684 0.38 LAIR2
leukocyte-associated immunoglobulin-like receptor 2
1508
0.24
chr2_234877344_234877495 0.38 TRPM8
transient receptor potential cation channel, subfamily M, member 8
2157
0.33
chrX_70825774_70825925 0.38 CXCR3
chemokine (C-X-C motif) receptor 3
12511
0.17
chr3_112526326_112526477 0.38 ENSG00000242770
.
5076
0.26
chr7_43651721_43652066 0.38 STK17A
serine/threonine kinase 17a
29229
0.15
chr1_100733692_100733847 0.38 RTCA
RNA 3'-terminal phosphate cyclase
1924
0.23
chr2_238350298_238350449 0.37 AC112721.1
Uncharacterized protein
16454
0.18
chr5_130732139_130732434 0.37 CDC42SE2
CDC42 small effector 2
10987
0.3
chr13_44058661_44058812 0.37 ENOX1
ecto-NOX disulfide-thiol exchanger 1
123523
0.06
chr2_171210862_171211026 0.37 AC012594.1

3316
0.37
chr7_55618910_55619061 0.37 VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
1560
0.45
chr10_102483469_102483620 0.37 PAX2
paired box 2
21924
0.22
chr10_7825346_7825497 0.37 KIN
KIN, antigenic determinant of recA protein homolog (mouse)
4523
0.21
chr3_18666283_18666434 0.37 ENSG00000228956
.
69021
0.14
chr6_16422995_16423237 0.37 ENSG00000265642
.
5638
0.33
chr1_116929404_116929555 0.36 AL136376.1
Uncharacterized protein
2761
0.21
chr1_110073598_110073848 0.36 GPR61
G protein-coupled receptor 61
8771
0.1
chr2_106711761_106712080 0.36 C2orf40
chromosome 2 open reading frame 40
29664
0.2
chr2_235332957_235333108 0.36 ARL4C
ADP-ribosylation factor-like 4C
72212
0.13
chr7_3108313_3108464 0.36 CARD11
caspase recruitment domain family, member 11
24809
0.21
chr12_120449270_120449421 0.36 CCDC64
coiled-coil domain containing 64
21672
0.18
chr20_3794059_3794376 0.36 AP5S1
adaptor-related protein complex 5, sigma 1 subunit
6961
0.12
chr3_4889780_4890066 0.36 ENSG00000239126
.
30463
0.18
chr2_225440019_225440259 0.36 CUL3
cullin 3
5597
0.34
chr7_144045634_144046113 0.36 OR2A1-AS1
OR2A1 antisense RNA 1
5479
0.14
chr5_35901302_35901453 0.35 IL7R
interleukin 7 receptor
25861
0.15
chr3_105501258_105501409 0.35 CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
80288
0.12
chr6_35336356_35336745 0.35 PPARD
peroxisome proliferator-activated receptor delta
26148
0.17
chr12_6182784_6182935 0.35 ENSG00000240533
.
22277
0.2
chr16_85823495_85823646 0.35 RP11-568J23.6

2451
0.17
chr5_130718609_130718935 0.35 CDC42SE2
CDC42 small effector 2
2527
0.42
chr2_190520851_190521002 0.35 ASNSD1
asparagine synthetase domain containing 1
5185
0.2
chr11_129758569_129758720 0.35 NFRKB
nuclear factor related to kappaB binding protein
4127
0.27
chr13_51697155_51697306 0.35 ENSG00000222920
.
95242
0.07
chr2_12268194_12268483 0.35 ENSG00000264089
.
70918
0.12
chr2_204590325_204590641 0.35 CD28
CD28 molecule
19067
0.21
chr5_158906182_158906378 0.35 ENSG00000266432
.
46666
0.18
chr8_41465512_41465663 0.35 RP11-360L9.8

13434
0.12
chr13_111823827_111823978 0.35 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
13383
0.19
chr16_68115229_68115482 0.35 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
3892
0.13
chr10_49537749_49537900 0.35 MAPK8
mitogen-activated protein kinase 8
22755
0.22
chr2_46579772_46580319 0.34 EPAS1
endothelial PAS domain protein 1
55504
0.13
chr13_74612544_74612695 0.34 KLF12
Kruppel-like factor 12
43433
0.22
chr3_11660538_11660689 0.34 VGLL4
vestigial like 4 (Drosophila)
6472
0.21
chr22_42700162_42700463 0.34 TCF20
transcription factor 20 (AR1)
39310
0.15
chr3_150440819_150441000 0.34 RP11-103G8.2

15155
0.16
chr11_75943202_75943433 0.34 WNT11
wingless-type MMTV integration site family, member 11
21537
0.18
chr9_33082201_33082509 0.34 SMU1
smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
5690
0.18
chr16_179998_180149 0.34 Z69666.2

4337
0.1
chr18_56326833_56326984 0.34 MALT1
mucosa associated lymphoid tissue lymphoma translocation gene 1
11710
0.14
chr7_142506914_142507240 0.34 PRSS3P2
protease, serine, 3 pseudogene 2
25946
0.15
chr15_80389126_80389277 0.34 ZFAND6
zinc finger, AN1-type domain 6
21668
0.19
chr17_8194100_8194251 0.34 RANGRF
RAN guanine nucleotide release factor
2179
0.15
chr15_69395724_69395875 0.33 GLCE
glucuronic acid epimerase
57174
0.1
chr2_106702316_106702467 0.33 C2orf40
chromosome 2 open reading frame 40
20135
0.23
chrX_17021536_17021687 0.33 REPS2
RALBP1 associated Eps domain containing 2
24944
0.19
chr3_107789257_107789408 0.33 CD47
CD47 molecule
10953
0.3
chr13_74833840_74834006 0.33 ENSG00000206617
.
29428
0.24
chr1_186274017_186274168 0.33 ENSG00000202025
.
6968
0.19
chr13_80023539_80023690 0.33 NDFIP2
Nedd4 family interacting protein 2
31673
0.14
chr5_167810412_167810563 0.33 WWC1
WW and C2 domain containing 1
12061
0.26
chr3_71540575_71540858 0.33 ENSG00000221264
.
50524
0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of TCF7L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.5 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.4 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.3 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0002517 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.0 0.2 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.4 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:1903521 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.4 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.2 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:1904019 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0014002 astrocyte development(GO:0014002)
0.0 0.1 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0072224 metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.2 GO:0043584 nose development(GO:0043584)
0.0 0.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.2 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.0 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.4 GO:0044349 nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0050860 regulation of T cell receptor signaling pathway(GO:0050856) negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0042510 regulation of tyrosine phosphorylation of Stat1 protein(GO:0042510)
0.0 0.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0072177 mesonephric duct development(GO:0072177)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.3 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.0 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.1 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.3 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.0 GO:0090196 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0032119 sequestering of zinc ion(GO:0032119)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 0.0 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0060456 positive regulation of digestive system process(GO:0060456)
0.0 0.1 GO:0001840 neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0 0.0 GO:0042508 tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0021549 cerebellum development(GO:0021549)
0.0 0.0 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.2 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.0 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.3 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.2 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.2 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.0 GO:0043921 modulation by host of viral transcription(GO:0043921) modulation by host of symbiont transcription(GO:0052472)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0070076 histone lysine demethylation(GO:0070076)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0002830 positive regulation of type 2 immune response(GO:0002830)
0.0 0.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.0 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.0 GO:0071637 monocyte chemotactic protein-1 production(GO:0071605) regulation of monocyte chemotactic protein-1 production(GO:0071637)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.0 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.1 GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.0 GO:0015919 peroxisomal membrane transport(GO:0015919)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.4 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.2 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.2 GO:0031672 A band(GO:0031672)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.0 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.2 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.5 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.0 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.0 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.5 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0 0.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0008443 phosphofructokinase activity(GO:0008443)
0.0 0.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.0 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 0.0 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.0 GO:0043140 3'-5' DNA helicase activity(GO:0043138) ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.0 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.8 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.1 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.4 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.0 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.0 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME IL 2 SIGNALING Genes involved in Interleukin-2 signaling
0.0 0.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family