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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for TEAD4

Z-value: 2.27

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Transcription factors associated with TEAD4

Gene Symbol	Gene ID	Gene Info
TEAD4 Ensembl NCBI GeneCards UniProt	ENSG00000197905.4	TEA domain transcription factor 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr12_3151541_3151787	TEAD4	31454	0.149350	-0.45	2.2e-01	Click!
chr12_3107682_3107833	TEAD4	12453	0.171222	-0.39	2.9e-01	Click!
chr12_3083887_3084038	TEAD4	14879	0.142360	-0.39	3.0e-01	Click!
chr12_3108487_3108638	TEAD4	11648	0.173569	-0.31	4.1e-01	Click!
chr12_3114098_3114249	TEAD4	6037	0.197041	-0.22	5.8e-01	Click!

Activity of the TEAD4 motif across conditions

Conditions sorted by the z-value of the TEAD4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_50045661_50045866	0.77	PARP8	poly (ADP-ribose) polymerase family, member 8	82372	0.11
chr10_14052331_14052633	0.70	FRMD4A	FERM domain containing 4A	1950	0.38
chr1_20015723_20015939	0.70	HTR6	5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled	24051	0.16
chr8_29960313_29960521	0.68	LEPROTL1	leptin receptor overlapping transcript-like 1	961	0.49
chr21_34934879_34935141	0.68	SON	SON DNA binding protein	7655	0.13
chr3_113941510_113941806	0.64	RP11-553L6.2		8420	0.17
chr1_168391686_168391980	0.60	ENSG00000207974	.	47071	0.16
chr6_112162915_112163066	0.60	FYN	FYN oncogene related to SRC, FGR, YES	3157	0.36
chr6_112311435_112311966	0.60	WISP3	WNT1 inducible signaling pathway protein 3	63575	0.11
chr8_81983197_81983348	0.60	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	41031	0.2
chr5_66512764_66513039	0.59	CD180	CD180 molecule	20274	0.26
chr12_40022149_40022321	0.59	C12orf40	chromosome 12 open reading frame 40	2250	0.36
chr7_55537965_55538664	0.59	VOPP1	vesicular, overexpressed in cancer, prosurvival protein 1	45456	0.17
chr14_64332649_64332871	0.58	SYNE2	spectrin repeat containing, nuclear envelope 2	13028	0.21
chr6_143185888_143186182	0.58	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	27851	0.23
chr11_117860476_117860627	0.55	IL10RA	interleukin 10 receptor, alpha	3442	0.24
chr4_90203894_90204205	0.55	GPRIN3	GPRIN family member 3	25112	0.26
chr12_9807704_9808028	0.55	RP11-705C15.2		1587	0.25
chr5_56485990_56486141	0.55	GPBP1	GC-rich promoter binding protein 1	14292	0.22
chr2_135434814_135435028	0.54	TMEM163	transmembrane protein 163	41649	0.2
chr19_23981940_23982139	0.53	RP11-255H23.2		8465	0.2
chr17_53193184_53193335	0.53	STXBP4	syntaxin binding protein 4	116082	0.06
chr3_105468113_105468264	0.52	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	47143	0.21
chr2_177716567_177716850	0.52	ENSG00000206866	.	78110	0.11
chr8_101936868_101937060	0.51	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta	10319	0.16
chr22_43773505_43773726	0.51	MPPED1	metallophosphoesterase domain containing 1	33587	0.16
chr5_93912907_93913170	0.51	ENSG00000211498	.	1436	0.44
chr1_235048677_235048938	0.51	ENSG00000239690	.	8874	0.27
chr20_24008676_24008902	0.50	GGTLC1	gamma-glutamyltransferase light chain 1	39373	0.2
chr14_54978743_54978894	0.50	CGRRF1	cell growth regulator with ring finger domain 1	2194	0.33
chr1_101394971_101395556	0.50	SLC30A7	solute carrier family 30 (zinc transporter), member 7	32121	0.12
chr5_168002134_168002285	0.49	PANK3	pantothenate kinase 3	4146	0.22
chr3_18768681_18768832	0.49	ENSG00000228956	.	18480	0.3
chr10_7431182_7431333	0.49	SFMBT2	Scm-like with four mbt domains 2	19450	0.27
chr7_6298731_6299016	0.49	CYTH3	cytohesin 3	13402	0.18
chr2_109965626_109966212	0.49	ENSG00000265965	.	35838	0.23
chr12_92425801_92426181	0.49	C12orf79	chromosome 12 open reading frame 79	104806	0.07
chr9_92077290_92077553	0.49	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	6553	0.25
chr11_116796998_116797221	0.48	SIK3	SIK family kinase 3	30651	0.13
chr3_18477634_18477910	0.48	SATB1	SATB homeobox 1	1027	0.57
chr3_107695991_107696269	0.48	CD47	CD47 molecule	81078	0.11
chr2_143882482_143882858	0.48	ARHGAP15	Rho GTPase activating protein 15	4213	0.31
chr4_3198000_3198220	0.48	HTT	huntingtin	36021	0.16
chr4_109025880_109026142	0.48	LEF1	lymphoid enhancer-binding factor 1	61446	0.12
chr18_21583459_21583679	0.48	TTC39C	tetratricopeptide repeat domain 39C	10815	0.17
chr13_100023381_100023651	0.48	ENSG00000207719	.	15131	0.21
chr1_197093308_197093459	0.48	ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	10891	0.23
chr10_126404133_126404651	0.47	FAM53B-AS1	FAM53B antisense RNA 1	11639	0.18
chr14_55805225_55805378	0.47	RP11-665C16.5		918	0.65
chr14_22979407_22979640	0.47	TRAJ15	T cell receptor alpha joining 15	19057	0.09
chr5_118524120_118524302	0.47	ENSG00000264536	.	33879	0.15
chr6_106628525_106628811	0.47	RP1-134E15.3		80653	0.08
chr8_126945463_126945895	0.47	ENSG00000206695	.	32484	0.25
chr2_106778172_106778934	0.46	UXS1	UDP-glucuronate decarboxylase 1	1472	0.48
chr20_57692997_57693226	0.46	ZNF831	zinc finger protein 831	72964	0.08
chr2_106669871_106670398	0.46	C2orf40	chromosome 2 open reading frame 40	9616	0.28
chr22_40347330_40347523	0.46	GRAP2	GRB2-related adaptor protein 2	4605	0.19
chr14_22999356_22999596	0.46	TRAJ15	T cell receptor alpha joining 15	896	0.43
chrX_49144105_49144462	0.46	PPP1R3F	protein phosphatase 1, regulatory subunit 3F	7044	0.09
chr14_90107458_90107875	0.46	ENSG00000252655	.	9581	0.14
chr13_100312168_100312333	0.45	ENSG00000263615	.	16937	0.17
chrX_135727576_135727799	0.45	CD40LG	CD40 ligand	2665	0.24
chr17_35031754_35032157	0.45	MRM1	mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)	73564	0.08
chr16_74633092_74633243	0.45	GLG1	golgi glycoprotein 1	7825	0.23
chr7_8171333_8171763	0.45	AC006042.6		17893	0.2
chr3_56929920_56930101	0.45	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	20489	0.22
chr2_162808795_162809052	0.45	ENSG00000253046	.	33631	0.21
chr9_92073183_92073407	0.44	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	2427	0.36
chr10_6078407_6078712	0.44	IL2RA	interleukin 2 receptor, alpha	10595	0.14
chr3_118944578_118944729	0.44	B4GALT4-AS1	B4GALT4 antisense RNA 1	680	0.64
chr19_16493238_16493503	0.44	ENSG00000243745	.	16400	0.14
chr3_98244320_98244471	0.44	CLDND1	claudin domain containing 1	2485	0.2
chr4_153451700_153451986	0.44	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	4310	0.23
chr10_14571608_14571759	0.43	FAM107B	family with sequence similarity 107, member B	3026	0.32
chrX_15767254_15767522	0.43	CA5B	carbonic anhydrase VB, mitochondrial	638	0.71
chr14_61873387_61873538	0.43	PRKCH	protein kinase C, eta	16050	0.24
chr15_87158728_87158950	0.43	RP11-182L7.1		15528	0.3
chrX_103367091_103367582	0.43	ZCCHC18	zinc finger, CCHC domain containing 18	10134	0.18
chr4_114820270_114820674	0.42	RP11-26P13.2		43940	0.19
chr18_72041117_72041435	0.42	C18orf63	chromosome 18 open reading frame 63	58228	0.12
chr14_106453494_106453674	0.42	IGHV1-2	immunoglobulin heavy variable 1-2	414	0.54
chr1_161034126_161034311	0.42	AL591806.1	Uncharacterized protein	1437	0.2
chr7_8056755_8056906	0.42	AC006042.7		47296	0.13
chr3_128736783_128736934	0.42	EFCC1	EF-hand and coiled-coil domain containing 1	16386	0.13
chr22_40719595_40719746	0.42	ADSL	adenylosuccinate lyase	22837	0.17
chr11_58263488_58263639	0.42	OR5B21	olfactory receptor, family 5, subfamily B, member 21	12015	0.18
chr1_89729146_89729620	0.42	RP4-620F22.2		3118	0.24
chr2_204578612_204578763	0.41	CD28	CD28 molecule	7271	0.25
chrX_78515923_78516081	0.41	GPR174	G protein-coupled receptor 174	89533	0.1
chr4_109030822_109031208	0.41	LEF1	lymphoid enhancer-binding factor 1	56442	0.13
chr2_30471107_30471394	0.41	LBH	limb bud and heart development	16204	0.23
chr13_41171454_41171694	0.41	AL133318.1	Uncharacterized protein	60251	0.12
chr17_78595395_78595732	0.41	RPTOR	regulatory associated protein of MTOR, complex 1	76295	0.1
chr12_108691233_108691384	0.40	CMKLR1	chemokine-like receptor 1	20386	0.25
chr3_177360373_177360796	0.40	ENSG00000200288	.	18387	0.29
chr6_27122996_27123197	0.40	ENSG00000265565	.	7691	0.12
chr7_144527737_144527888	0.40	TPK1	thiamin pyrophosphokinase 1	5334	0.27
chr2_8443407_8443630	0.40	AC011747.7		372378	0.01
chr5_169693142_169693293	0.40	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	1083	0.57
chr7_86832265_86832559	0.40	DMTF1	cyclin D binding myb-like transcription factor 1	9371	0.18
chr5_156696862_156697210	0.40	CYFIP2	cytoplasmic FMR1 interacting protein 2	674	0.62
chr4_109037043_109037432	0.40	LEF1	lymphoid enhancer-binding factor 1	50220	0.14
chr12_90096202_90096439	0.39	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	6288	0.22
chr6_131528915_131529066	0.39	AKAP7	A kinase (PRKA) anchor protein 7	7023	0.32
chr6_143862532_143862683	0.39	PHACTR2	phosphatase and actin regulator 2	4625	0.18
chr18_60826112_60826263	0.39	RP11-299P2.1		7634	0.24
chr21_34615867_34616089	0.39	AP000295.9		3101	0.19
chr3_111259347_111259498	0.39	CD96	CD96 molecule	1434	0.52
chr19_19981768_19982042	0.39	ZNF253	zinc finger protein 253	5189	0.14
chr12_806617_806813	0.39	NINJ2	ninjurin 2	33770	0.14
chr7_131008967_131009118	0.39	ENSG00000236753	.	3434	0.27
chr6_398090_398241	0.39	IRF4	interferon regulatory factor 4	6426	0.3
chr3_151916036_151916249	0.39	MBNL1	muscleblind-like splicing regulator 1	69687	0.11
chr10_1980969_1981361	0.39	ENSG00000252998	.	159196	0.04
chr5_133439080_133439473	0.38	TCF7	transcription factor 7 (T-cell specific, HMG-box)	11126	0.22
chr2_198078183_198078504	0.38	ANKRD44	ankyrin repeat domain 44	15581	0.19
chr14_24079189_24079472	0.38	DHRS2	dehydrogenase/reductase (SDR family) member 2	19994	0.12
chr11_128603867_128604195	0.38	FLI1	Fli-1 proto-oncogene, ETS transcription factor	30654	0.16
chr11_14669672_14669983	0.38	PDE3B	phosphodiesterase 3B, cGMP-inhibited	4450	0.25
chr11_128480609_128480984	0.38	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	23343	0.2
chr1_101416000_101416317	0.38	SLC30A7	solute carrier family 30 (zinc transporter), member 7	11226	0.16
chr14_21967123_21967325	0.38	METTL3	methyltransferase like 3	10472	0.11
chr14_22974347_22974498	0.38	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	18251	0.09
chr2_148256921_148257279	0.38	ENSG00000202074	.	3992	0.25
chr18_9096080_9096231	0.38	NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	6473	0.19
chrX_131346377_131346528	0.38	RAP2C-AS1	RAP2C antisense RNA 1	4723	0.25
chrX_39168040_39168409	0.38	ENSG00000207122	.	227686	0.02
chr21_36405752_36405903	0.38	RUNX1	runt-related transcription factor 1	15635	0.3
chr15_61137119_61137414	0.38	RP11-554D20.1		80327	0.1
chr16_50765455_50765735	0.38	RP11-327F22.2		9032	0.11
chr6_3076493_3076644	0.37	RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	464	0.74
chr8_67518848_67519042	0.37	MYBL1	v-myb avian myeloblastosis viral oncogene homolog-like 1	6197	0.19
chr10_13159902_13160147	0.37	OPTN	optineurin	1756	0.36
chr12_11816168_11816324	0.37	ETV6	ets variant 6	13458	0.26
chr2_198127644_198128365	0.37	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	39239	0.13
chr22_50906991_50907425	0.37	SBF1	SET binding factor 1	6163	0.09
chrX_18373480_18373720	0.37	SCML2	sex comb on midleg-like 2 (Drosophila)	753	0.73
chr3_46019508_46019702	0.37	FYCO1	FYVE and coiled-coil domain containing 1	6882	0.19
chr13_109064155_109064389	0.37	ENSG00000223177	.	110593	0.07
chr1_27072713_27073114	0.37	ARID1A	AT rich interactive domain 1A (SWI-like)	17042	0.12
chr10_99612159_99612310	0.37	GOLGA7B	golgin A7 family, member B	2238	0.29
chr3_186749746_186749924	0.37	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	6564	0.26
chr16_17087285_17087647	0.37	CTD-2576D5.4		140895	0.05
chr18_77195690_77195983	0.37	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	35444	0.19
chr13_74667324_74667490	0.37	KLF12	Kruppel-like factor 12	40987	0.22
chr7_128776931_128777082	0.37	TSPAN33	tetraspanin 33	7706	0.15
chr10_11247696_11247867	0.37	RP3-323N1.2		34442	0.18
chr2_231663134_231663369	0.37	ENSG00000201044	.	46395	0.13
chr2_68379671_68380108	0.37	WDR92	WD repeat domain 92	4716	0.18
chr15_87157125_87157276	0.37	RP11-182L7.1		17167	0.3
chr17_46376031_46376182	0.37	AC090627.1		4369	0.21
chr14_22698482_22698741	0.37	ENSG00000238634	.	87724	0.08
chr15_81599414_81599572	0.36	IL16	interleukin 16	7736	0.19
chr3_112210660_112210811	0.36	BTLA	B and T lymphocyte associated	7470	0.25
chrX_16545998_16546149	0.36	ENSG00000239333	.	11489	0.25
chr3_136849832_136850088	0.36	IL20RB-AS1	IL20RB antisense RNA 1	148922	0.04
chr14_72986279_72986635	0.36	RGS6	regulator of G-protein signaling 6	60080	0.16
chr8_61706063_61706431	0.36	RP11-33I11.2		15918	0.26
chr6_139583942_139584404	0.36	TXLNB	taxilin beta	439	0.84
chr4_114818966_114819117	0.36	RP11-26P13.2		45371	0.18
chr2_7052511_7052662	0.36	RNF144A	ring finger protein 144A	4937	0.2
chr3_108581508_108581689	0.36	TRAT1	T cell receptor associated transmembrane adaptor 1	39979	0.18
chr3_142883731_142883882	0.36	ENSG00000211483	.	684	0.76
chr18_67622046_67622197	0.36	CD226	CD226 molecule	1785	0.49
chr14_59621655_59621806	0.36	DAAM1	dishevelled associated activator of morphogenesis 1	33668	0.24
chr1_198644139_198644352	0.36	RP11-553K8.5		8055	0.26
chr7_27992758_27992993	0.36	JAZF1	JAZF zinc finger 1	38800	0.18
chr14_99689376_99689586	0.36	AL109767.1		39804	0.16
chr6_71308932_71309083	0.36	C6orf57	chromosome 6 open reading frame 57	32387	0.2
chr2_47175979_47176171	0.36	MCFD2	multiple coagulation factor deficiency 2	7081	0.15
chr13_101237003_101237164	0.36	GGACT	gamma-glutamylamine cyclotransferase	832	0.64
chr4_124365266_124365560	0.36	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	44290	0.21
chr1_174923612_174923763	0.35	RP1-102G20.5		289	0.89
chr9_137193728_137193947	0.35	RXRA	retinoid X receptor, alpha	24589	0.22
chr17_33543338_33543516	0.35	RP11-799D4.4		21573	0.11
chr6_112125082_112125233	0.35	FYN	FYN oncogene related to SRC, FGR, YES	5531	0.31
chr20_31561789_31561940	0.35	EFCAB8	EF-hand calcium binding domain 8	14213	0.15
chr1_235409251_235409407	0.35	ARID4B	AT rich interactive domain 4B (RBP1-like)	32098	0.15
chr2_98337410_98337600	0.35	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	3828	0.21
chr12_72160885_72161036	0.35	RAB21	RAB21, member RAS oncogene family	12306	0.22
chr8_145053399_145053643	0.35	PLEC	plectin	2619	0.14
chr11_60860531_60860682	0.35	CD5	CD5 molecule	9261	0.18
chr1_207104273_207104487	0.35	FAIM3	Fas apoptotic inhibitory molecule 3	7788	0.15
chr12_6552615_6553042	0.35	CD27	CD27 molecule	1205	0.29
chr3_107791297_107791464	0.35	CD47	CD47 molecule	13001	0.3
chr7_106973665_106973906	0.35	ENSG00000221356	.	38455	0.18
chr2_182472121_182472272	0.35	CERKL	ceramide kinase-like	49537	0.14
chr14_77836108_77836259	0.35	SAMD15	sterile alpha motif domain containing 15	6849	0.12
chr14_66304286_66304437	0.35	CTD-2014B16.3	Uncharacterized protein	166880	0.04
chr9_129231460_129231761	0.35	ENSG00000252985	.	42438	0.14
chr12_69068762_69069251	0.35	NUP107	nucleoporin 107kDa	11508	0.2
chr21_43657784_43657986	0.35	ENSG00000223262	.	16602	0.16
chr6_53097138_53097313	0.35	ENSG00000206908	.	13166	0.18
chr17_17768182_17768333	0.35	TOM1L2	target of myb1-like 2 (chicken)	2163	0.27
chr2_28848726_28848877	0.35	PLB1	phospholipase B1	4652	0.23
chr3_16345787_16346236	0.35	RP11-415F23.2		9935	0.17
chr13_30509818_30509969	0.35	LINC00572	long intergenic non-protein coding RNA 572	9105	0.3
chr10_73849376_73849636	0.35	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	716	0.73
chr15_38902199_38902350	0.35	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	44498	0.15
chr8_68591514_68591665	0.34	ENSG00000221660	.	32278	0.19

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	GO:0002326	B cell lineage commitment(GO:0002326)
0.2	1.0	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2	1.0	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.2	0.7	GO:0010459	negative regulation of heart rate(GO:0010459)
0.2	0.9	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2	0.4	GO:0006154	adenosine catabolic process(GO:0006154)
0.2	0.5	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2	0.2	GO:0002249	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.2	1.2	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.2	1.3	GO:0002836	regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.2	0.5	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.2	0.5	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.2	0.2	GO:0002517	tolerance induction to self antigen(GO:0002513) T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.2	0.6	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.3	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1	0.4	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.4	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.4	GO:0006772	thiamine metabolic process(GO:0006772)
0.1	0.9	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.4	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.8	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.5	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.6	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.3	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1	0.3	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.5	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.8	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.4	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.2	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1	0.2	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.4	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1	0.3	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.2	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.4	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.1	2.3	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.2	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.1	0.2	GO:0034776	response to histamine(GO:0034776)
0.1	0.3	GO:0015917	aminophospholipid transport(GO:0015917)
0.1	0.3	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.3	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.1	0.3	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.1	0.7	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.2	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.1	0.4	GO:0060023	soft palate development(GO:0060023)
0.1	0.2	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.2	GO:0002724	regulation of T cell cytokine production(GO:0002724)
0.1	0.2	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.1	0.2	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.1	0.1	GO:0002335	mature B cell differentiation(GO:0002335)
0.1	0.4	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.8	GO:0030260	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.1	0.1	GO:0034587	piRNA metabolic process(GO:0034587)
0.1	0.1	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.1	0.2	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.1	0.2	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.4	GO:0046033	AMP metabolic process(GO:0046033)
0.1	0.2	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.5	GO:0002063	chondrocyte development(GO:0002063)
0.1	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.5	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.1	0.5	GO:0060123	regulation of growth hormone secretion(GO:0060123)
0.1	0.6	GO:0043368	positive T cell selection(GO:0043368)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.3	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.1	0.1	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	0.1	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.1	0.5	GO:0006198	cAMP catabolic process(GO:0006198)
0.1	0.6	GO:0032456	endocytic recycling(GO:0032456)
0.1	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.2	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.1	0.2	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.3	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.2	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.1	0.2	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.1	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1	0.3	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.2	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.2	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1	0.3	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.1	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.1	0.2	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.2	GO:0002507	tolerance induction(GO:0002507)
0.1	0.2	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.1	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.3	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.2	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.1	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.4	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.2	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.1	0.1	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.3	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.2	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.1	GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003339)
0.0	0.0	GO:0033622	integrin activation(GO:0033622)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	3.1	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.2	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759)
0.0	0.2	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.2	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.1	GO:0031223	auditory behavior(GO:0031223)
0.0	0.0	GO:0071504	cellular response to heparin(GO:0071504)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.9	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.4	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.2	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.1	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.3	GO:0032367	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.3	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.7	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.2	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.6	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.2	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.0	GO:0032621	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.4	GO:0000303	response to superoxide(GO:0000303)
0.0	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.2	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	1.2	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.3	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.0	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.2	GO:0075713	establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.1	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.3	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.2	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.9	GO:1901185	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.1	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.1	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.2	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.2	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.2	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.8	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0033567	lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.2	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.2	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.5	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.1	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0033504	floor plate development(GO:0033504)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0034393	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:0070664	negative regulation of leukocyte proliferation(GO:0070664)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.2	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.2	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	0.2	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0002606	positive regulation of antigen processing and presentation(GO:0002579) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.4	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.2	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0046668	retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.1	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.1	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.3	GO:0031648	protein destabilization(GO:0031648)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.4	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0043628	ncRNA 3'-end processing(GO:0043628)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.2	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.2	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.0	GO:1903504	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.0	GO:0032459	regulation of protein oligomerization(GO:0032459)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.3	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.4	GO:1904590	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.1	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.1	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.0	0.0	GO:0032692	negative regulation of interleukin-1 production(GO:0032692)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.2	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.0	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.0	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0032814	regulation of natural killer cell activation(GO:0032814)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.0	0.0	GO:0060620	negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.0	GO:0007097	nuclear migration(GO:0007097)
0.0	0.0	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0	0.1	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.2	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0016241	regulation of macroautophagy(GO:0016241) negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0036473	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.1	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.0	GO:0097028	myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.2	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.1	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.4	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0017085	response to insecticide(GO:0017085)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.0	GO:0010996	response to auditory stimulus(GO:0010996)
0.0	0.5	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.6	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	0.0	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.0	GO:0048865	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.1	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.2	GO:0009070	serine family amino acid biosynthetic process(GO:0009070)
0.0	0.0	GO:0060746	maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0	0.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.3	GO:0051224	negative regulation of protein transport(GO:0051224)
0.0	0.0	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0009732	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.0	GO:0044256	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.9	GO:0006921	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) execution phase of apoptosis(GO:0097194)
0.0	0.1	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.8	GO:0006338	chromatin remodeling(GO:0006338)
0.0	1.3	GO:0018196	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.0	GO:0001743	optic placode formation(GO:0001743)
0.0	0.1	GO:0072283	mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) renal vesicle morphogenesis(GO:0072077) metanephric renal vesicle morphogenesis(GO:0072283)
0.0	0.1	GO:0032292	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.1	GO:0046885	regulation of hormone biosynthetic process(GO:0046885)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.0	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0010824	regulation of centrosome duplication(GO:0010824)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.1	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.0	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.0	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:0070897	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.1	GO:0000239	pachytene(GO:0000239)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0021681	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0035637	transmission of nerve impulse(GO:0019226) multicellular organismal signaling(GO:0035637)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.0	GO:0001913	T cell mediated cytotoxicity(GO:0001913)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.3	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.3	GO:0043487	regulation of RNA stability(GO:0043487)
0.0	0.1	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0007099	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.1	GO:0031112	positive regulation of microtubule polymerization or depolymerization(GO:0031112) positive regulation of microtubule polymerization(GO:0031116)
0.0	0.3	GO:0016073	snRNA metabolic process(GO:0016073)
0.0	0.1	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.0	0.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0043084	penile erection(GO:0043084)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.1	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.1	GO:0006105	succinate metabolic process(GO:0006105)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.0	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.0	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0007625	grooming behavior(GO:0007625)
0.0	0.4	GO:0031047	gene silencing by RNA(GO:0031047)
0.0	0.0	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0033028	myeloid cell apoptotic process(GO:0033028)
0.0	0.0	GO:0072655	establishment of protein localization to mitochondrion(GO:0072655)
0.0	0.3	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.2	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.1	GO:0031848	telomere capping(GO:0016233) protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.9	GO:0000236	mitotic prometaphase(GO:0000236)
0.0	0.1	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.3	GO:0072512	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.0	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.5	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0043049	otic placode formation(GO:0043049)
0.0	0.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.0	GO:0021823	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.0	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.0	0.0	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.1	GO:0006278	RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0	0.9	GO:0022904	respiratory electron transport chain(GO:0022904)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.0	GO:0042435	indole-containing compound biosynthetic process(GO:0042435)
0.0	0.1	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.0	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.2	GO:1901661	quinone metabolic process(GO:1901661)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.0	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.1	GO:0070193	synaptonemal complex organization(GO:0070193)
0.0	0.1	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.0	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.0	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.0	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.0	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.1	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0000466	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0045047	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.0	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.0	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.0	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.5	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.2	GO:0030317	sperm motility(GO:0030317)
0.0	0.0	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.0	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.1	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.3	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.0	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.4	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.7	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.5	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.8	GO:0001891	phagocytic cup(GO:0001891)
0.1	1.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.3	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.3	GO:0005827	polar microtubule(GO:0005827)
0.1	0.4	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.5	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.8	GO:0001772	immunological synapse(GO:0001772)
0.1	0.3	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.9	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.1	0.4	GO:0042827	platelet dense granule(GO:0042827)
0.1	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.5	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.3	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.6	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.3	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.5	GO:0045120	pronucleus(GO:0045120)
0.0	0.4	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.0	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.3	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.4	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.2	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.2	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.5	GO:0043209	myelin sheath(GO:0043209)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.3	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.2	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.5	GO:0005844	polysome(GO:0005844)
0.0	0.4	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.3	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.2	GO:0042627	chylomicron(GO:0042627)
0.0	3.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	1.1	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.0	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.2	GO:1904949	ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.4	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.0	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.3	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.6	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.3	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.0	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.2	GO:0008278	cohesin complex(GO:0008278)
0.0	0.1	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.3	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.6	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.4	GO:0043204	perikaryon(GO:0043204)
0.0	1.3	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.3	GO:0015030	Cajal body(GO:0015030)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.9	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.2	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.3	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.3	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.0	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.2	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.3	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.0	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	1.0	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.0	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0042825	MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)
0.0	0.1	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.5	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.4	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	1.5	GO:0000785	chromatin(GO:0000785)
0.0	0.3	GO:0030863	cortical cytoskeleton(GO:0030863)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0005753	mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.0	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.0	GO:0097525	spliceosomal snRNP complex(GO:0097525)
0.0	1.0	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.2	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.9	GO:0019717	obsolete synaptosome(GO:0019717)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.0	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.4	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.4	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.5	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.4	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.4	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.4	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.5	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.3	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.1	1.3	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.9	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.3	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.7	GO:0030332	cyclin binding(GO:0030332)
0.1	0.6	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.5	GO:0070513	death domain binding(GO:0070513)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.1	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.1	0.4	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.8	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.4	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.4	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.4	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.2	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.3	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.1	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	0.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.1	0.5	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1	0.2	GO:0043398	HLH domain binding(GO:0043398)
0.1	0.2	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	0.5	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.2	GO:0001077	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	2.2	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	0.4	GO:0016778	diphosphotransferase activity(GO:0016778)
0.1	0.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.2	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.2	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.1	GO:0060229	lipase activator activity(GO:0060229)
0.1	1.1	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	0.5	GO:0046625	sphingolipid binding(GO:0046625)
0.1	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	0.4	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.8	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	1.1	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.3	GO:0034452	dynactin binding(GO:0034452)
0.0	0.4	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.3	GO:0050733	RS domain binding(GO:0050733)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.4	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.3	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	1.0	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	1.1	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.9	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	1.0	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.3	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.6	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.5	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.3	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.2	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.9	GO:0003823	antigen binding(GO:0003823)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421)
0.0	0.2	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.4	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.2	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.4	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.2	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.9	GO:0101005	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.2	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.0	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.3	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.0	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.3	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.4	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.3	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.7	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.0	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.1	GO:0016307	phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.0	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.5	GO:0019003	GDP binding(GO:0019003)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.2	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.2	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	1.0	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.0	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.2	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0046527	glucosyltransferase activity(GO:0046527)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.5	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.0	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.2	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.0	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.1	GO:0044620	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.2	GO:0043022	ribosome binding(GO:0043022)
0.0	0.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.0	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.0	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.5	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0016776	phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.3	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.6	GO:0008137	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.0	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.3	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0003678	DNA helicase activity(GO:0003678)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.4	GO:0019205	nucleobase-containing compound kinase activity(GO:0019205)
0.0	0.3	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0008252	nucleotidase activity(GO:0008252)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.0	GO:0052742	phosphatidylinositol kinase activity(GO:0052742)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.0	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.0	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.0	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.0	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.0	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.2	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0002039	p53 binding(GO:0002039)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.0	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.0	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	1.2	GO:0003702	obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0	0.0	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	1.2	GO:0003690	double-stranded DNA binding(GO:0003690)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0000049	tRNA binding(GO:0000049)
0.0	0.1	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.2	GO:0005035	death receptor activity(GO:0005035)
0.0	0.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	7.7	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.1	0.9	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.9	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	3.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1	1.7	PID REELIN PATHWAY	Reelin signaling pathway
0.1	1.0	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.5	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	0.8	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.8	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.9	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.9	PID MYC PATHWAY	C-MYC pathway
0.0	0.5	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.4	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	1.0	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.8	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.3	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.6	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.9	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	1.4	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.4	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.4	PID BCR 5PATHWAY	BCR signaling pathway
0.0	1.1	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	0.9	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.2	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.6	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.8	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.0	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.2	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.0	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.3	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.8	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	1.9	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.9	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	0.6	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.5	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	1.5	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	2.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.1	1.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	0.7	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	0.9	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.1	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	3.4	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.8	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	1.0	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	1.3	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.7	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.6	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.7	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.8	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.4	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.4	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus
0.0	0.1	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.7	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.4	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.2	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.6	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.7	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.3	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.9	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.5	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.0	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.5	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.3	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.5	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	2.1	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.4	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.1	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.3	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.1	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0	0.2	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.9	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.1	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.0	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.3	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.0	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha

Results for TEAD4

Z-value: 2.27

Motif logo

Transcription factors associated with TEAD4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the TEAD4 motif across conditions

Conditions sorted by the z-value of the TEAD4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TEAD4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: