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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for TFAP2B

Z-value: 1.60

Motif logo

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Transcription factors associated with TFAP2B

Gene Symbol Gene ID Gene Info
TFAP2B
ENSG00000008196.8 transcription factor AP-2 beta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_50783493_50783702TFAP2B28390.410011-0.826.2e-03Click!
chr6_50903539_50903690TFAP2B1171750.068877-0.791.2e-02Click!
chr6_50929546_50929733TFAP2B1432000.049753-0.761.7e-02Click!
chr6_50929115_50929282TFAP2B1427590.050012-0.693.9e-02Click!
chr6_50789163_50789314TFAP2B27990.4145490.694.1e-02Click!

Activity of the TFAP2B motif across conditions

Conditions sorted by the z-value of the TFAP2B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_228336809_228337095 1.19 GJC2
 gap junction protein, gamma 2, 47kDa
 601
 0.58
chr9_133302644_133302795 0.80 HMCN2
 hemicentin 2
 2950
 0.21
chr10_112168315_112168466 0.70 ENSG00000221359
 .
 25609
 0.19
chr7_4771612_4771763 0.67 FOXK1
 forkhead box K1
 8803
 0.19
chr19_4713192_4713546 0.67 DPP9
 dipeptidyl-peptidase 9
 949
 0.43
chr15_74679279_74679430 0.66 CYP11A1
 cytochrome P450, family 11, subfamily A, polypeptide 1
 19273
 0.13
chr17_78933014_78933165 0.66 CTD-2561B21.3
2424
 0.18
chr10_88409177_88409328 0.65 OPN4
 opsin 4
 5062
 0.22
chr6_37666285_37666474 0.63 MDGA1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 613
 0.81
chr9_36859555_36859706 0.63 RP11-344B23.2
3078
 0.23
chr14_105445324_105445475 0.63 AHNAK2
 AHNAK nucleoprotein 2
 705
 0.63
chr4_6272197_6272532 0.62 WFS1
 Wolfram syndrome 1 (wolframin)
 787
 0.74
chr20_31384666_31384857 0.62 DNMT3B
 DNA (cytosine-5-)-methyltransferase 3 beta
 17103
 0.16
chr12_124907481_124907632 0.61 NCOR2
 nuclear receptor corepressor 2
 34186
 0.22
chr6_106590141_106590398 0.61 RP1-134E15.3
42254
 0.16
chr14_99714170_99714435 0.61 AL109767.1
14983
 0.21
chr22_20226986_20227137 0.59 RTN4R
 reticulon 4 receptor
 4146
 0.16
chr11_64609797_64609948 0.58 CDC42BPG
 CDC42 binding protein kinase gamma (DMPK-like)
 2169
 0.18
chr22_29705214_29705587 0.58 GAS2L1
 growth arrest-specific 2 like 1
 2352
 0.17
chr4_3439247_3439398 0.57 HGFAC
 HGF activator
 4292
 0.21
chr16_70774609_70775132 0.56 VAC14
 Vac14 homolog (S. cerevisiae)
 3613
 0.18
chr1_19338582_19338733 0.56 IFFO2
 intermediate filament family orphan 2
 55477
 0.11
chr11_3109293_3109444 0.55 OSBPL5
 oxysterol binding protein-like 5
 6741
 0.16
chr9_101573597_101573748 0.55 GALNT12
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
 3691
 0.24
chr10_95229262_95229590 0.55 MYOF
 myoferlin
 12525
 0.19
chr1_193155079_193155230 0.54 B3GALT2
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
 630
 0.75
chr20_60945069_60945220 0.53 LAMA5
 laminin, alpha 5
 2776
 0.17
chr9_131675686_131675837 0.53 PHYHD1
 phytanoyl-CoA dioxygenase domain containing 1
 7413
 0.12
chr8_124553954_124554105 0.53 FBXO32
 F-box protein 32
 583
 0.77
chr5_175257162_175257313 0.52 CPLX2
 complexin 2
 31394
 0.18
chr3_55525759_55525910 0.52 WNT5A
 wingless-type MMTV integration site family, member 5A
 1861
 0.41
chr18_77937535_77937686 0.52 AC139100.3
3953
 0.23
chr10_5567726_5567877 0.52 RP11-116G8.5
96
 0.8
chr3_128016629_128016780 0.51 ENSG00000221067
 .
 64304
 0.11
chr9_140507478_140507731 0.51 C9orf37
 chromosome 9 open reading frame 37
 5661
 0.12
chr10_5605742_5605953 0.51 CALML3-AS1
 CALML3 antisense RNA 1
 37638
 0.11
chr12_123555934_123556085 0.50 PITPNM2
 phosphatidylinositol transfer protein, membrane-associated 2
 4633
 0.2
chr21_45715243_45715525 0.50 PFKL
 phosphofructokinase, liver
 4550
 0.11
chr1_6419961_6420398 0.50 ACOT7
 acyl-CoA thioesterase 7
 587
 0.69
chr15_45455194_45455384 0.50 RP11-519G16.2
7253
 0.1
chr16_85388240_85388391 0.49 RP11-680G10.1
 Uncharacterized protein
 2754
 0.33
chr12_94441922_94442073 0.48 ENSG00000223126
 .
 39174
 0.18
chr18_47205073_47205224 0.48 LIPG
 lipase, endothelial
 116433
 0.04
chr14_68935288_68935439 0.48 RAD51B
 RAD51 paralog B
 57136
 0.15
chr3_159505193_159505344 0.48 IQCJ-SCHIP1-AS1
 IQCJ-SCHIP1 readthrough antisense RNA 1
 18867
 0.15
chr12_52546716_52546867 0.47 KRT80
 keratin 80
 38993
 0.08
chr15_74472280_74472489 0.47 RP11-665J16.1
817
 0.48
chr4_6274602_6274753 0.47 WFS1
 Wolfram syndrome 1 (wolframin)
 3100
 0.35
chr7_130003657_130003904 0.46 CPA5
 carboxypeptidase A5
 498
 0.72
chr14_102172572_102172843 0.46 RP11-796G6.2
 Uncharacterized protein
 24067
 0.17
chr14_32414488_32414678 0.46 RP11-187E13.1
 Uncharacterized protein
 524
 0.84
chr6_116772654_116772805 0.46 ENSG00000265516
 .
 6256
 0.14
chr4_2801177_2801328 0.46 SH3BP2
 SH3-domain binding protein 2
 527
 0.8
chr7_1562610_1562761 0.45 MAFK
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
 7665
 0.14
chr7_73120336_73120487 0.45 ENSG00000265724
 .
 5236
 0.11
chr12_123429411_123429620 0.45 ABCB9
 ATP-binding cassette, sub-family B (MDR/TAP), member 9
 293
 0.88
chr1_26217938_26218089 0.45 STMN1
 stathmin 1
 13606
 0.08
chr3_42556058_42556209 0.45 VIPR1
 vasoactive intestinal peptide receptor 1
 12018
 0.15
chr11_118492770_118493048 0.45 AP002954.3
14429
 0.11
chr16_57831186_57831470 0.45 KIFC3
 kinesin family member C3
 348
 0.84
chr2_87842171_87842497 0.44 RP11-1399P15.1
64781
 0.13
chr11_94480509_94480660 0.44 RP11-867G2.8
7063
 0.23
chr14_23011383_23011534 0.44 TRAJ15
 T cell receptor alpha joining 15
 12878
 0.1
chr2_73297957_73298126 0.44 SFXN5
 sideroflexin 5
 761
 0.67
chr17_38600137_38600500 0.44 IGFBP4
 insulin-like growth factor binding protein 4
 605
 0.66
chr7_966993_967144 0.43 ADAP1
 ArfGAP with dual PH domains 1
 82
 0.96
chr19_4584744_4584943 0.43 SEMA6B
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
 25023
 0.09
chr14_104321166_104321317 0.43 PPP1R13B
 protein phosphatase 1, regulatory subunit 13B
 7314
 0.17
chr14_100040999_100041176 0.43 CCDC85C
 coiled-coil domain containing 85C
 1775
 0.33
chr19_49119290_49119441 0.43 FAM83E
 family with sequence similarity 83, member E
 1293
 0.21
chr1_43415164_43415399 0.42 SLC2A1
 solute carrier family 2 (facilitated glucose transporter), member 1
 9219
 0.19
chr12_3228682_3229088 0.42 TSPAN9-IT1
 TSPAN9 intronic transcript 1 (non-protein coding)
 30078
 0.18
chr7_150635354_150635936 0.42 KCNH2
 potassium voltage-gated channel, subfamily H (eag-related), member 2
 17349
 0.15
chr2_113392435_113392586 0.42 SLC20A1
 solute carrier family 20 (phosphate transporter), member 1
 10924
 0.19
chr4_6274786_6274937 0.42 WFS1
 Wolfram syndrome 1 (wolframin)
 3284
 0.34
chr2_97561253_97561466 0.42 FAM178B
 family with sequence similarity 178, member B
 2511
 0.22
chr16_68278720_68278897 0.42 PLA2G15
 phospholipase A2, group XV
 399
 0.66
chr17_41938860_41939011 0.42 CD300LG
 CD300 molecule-like family member g
 14391
 0.11
chr1_8255073_8255224 0.42 ENSG00000200975
 .
 11509
 0.23
chr2_111367449_111367600 0.42 AC123886.2
969
 0.61
chr2_219472098_219472249 0.42 PLCD4
 phospholipase C, delta 4
 315
 0.8
chr7_99760518_99760936 0.42 GAL3ST4
 galactose-3-O-sulfotransferase 4
 4126
 0.07
chr2_98964621_98964860 0.42 AC092675.4
1282
 0.37
chr17_79856034_79856185 0.41 NPB
 neuropeptide B
 2512
 0.09
chr22_20229537_20229756 0.41 RTN4R
 reticulon 4 receptor
 1561
 0.29
chr16_51189445_51189596 0.41 SALL1
 spalt-like transcription factor 1
 4334
 0.27
chr15_84048823_84048974 0.41 SH3GL3
 SH3-domain GRB2-like 3
 67082
 0.11
chr11_133818315_133818530 0.41 IGSF9B
 immunoglobulin superfamily, member 9B
 2235
 0.31
chr21_45502719_45503242 0.41 PWP2
 PWP2 periodic tryptophan protein homolog (yeast)
 24191
 0.15
chr2_133173738_133173889 0.41 GPR39
 G protein-coupled receptor 39
 334
 0.9
chr15_76488697_76488848 0.41 RP11-593F23.1
14945
 0.24
chr19_38879548_38879838 0.40 SPRED3
 sprouty-related, EVH1 domain containing 3
 559
 0.46
chr10_116267845_116267996 0.40 ABLIM1
 actin binding LIM protein 1
 18674
 0.24
chr1_210405648_210405799 0.40 SERTAD4
 SERTA domain containing 4
 421
 0.6
chr16_811264_811437 0.40 MSLN
 mesothelin
 252
 0.78
chr6_37592095_37592288 0.39 MDGA1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 21959
 0.22
chr10_80918331_80918482 0.39 ZMIZ1
 zinc finger, MIZ-type containing 1
 89614
 0.09
chr5_31988023_31988174 0.39 ENSG00000266243
 .
 51833
 0.13
chr2_235932870_235933072 0.39 SH3BP4
 SH3-domain binding protein 4
 29487
 0.26
chr2_69534306_69534473 0.39 ENSG00000252250
 .
 27343
 0.2
chr2_28977323_28977503 0.39 PPP1CB
 protein phosphatase 1, catalytic subunit, beta isozyme
 2694
 0.24
chr12_112195610_112195963 0.39 RP11-162P23.2
4092
 0.21
chr1_47077504_47077655 0.38 MOB3C
 MOB kinase activator 3C
 3226
 0.18
chr20_61468104_61468255 0.38 COL9A3
 collagen, type IX, alpha 3
 19016
 0.11
chr15_80472063_80472219 0.38 FAH
 fumarylacetoacetate hydrolase (fumarylacetoacetase)
 23848
 0.2
chr20_60892338_60892489 0.38 RP11-157P1.4
11032
 0.12
chr1_156631459_156631667 0.38 RP11-284F21.7
347
 0.75
chr11_112411093_112411244 0.38 ENSG00000212397
 .
 62007
 0.14
chr6_160399730_160400221 0.38 IGF2R
 insulin-like growth factor 2 receptor
 9844
 0.21
chr3_33033448_33033599 0.38 CCR4
 chemokine (C-C motif) receptor 4
 40457
 0.16
chr13_95898574_95898725 0.37 ENSG00000238463
 .
 36051
 0.17
chr2_110519060_110519211 0.37 RGPD5
 RANBP2-like and GRIP domain containing 5
 31200
 0.22
chr4_147443936_147444348 0.37 SLC10A7
 solute carrier family 10, member 7
 1019
 0.64
chr1_19255265_19255716 0.37 IFFO2
 intermediate filament family orphan 2
 17004
 0.16
chr7_578321_578511 0.37 ENSG00000252986
 .
 11954
 0.17
chr11_66137353_66137504 0.37 SLC29A2
 solute carrier family 29 (equilibrative nucleoside transporter), member 2
 1863
 0.14
chr17_79386944_79387260 0.37 ENSG00000266392
 .
 12524
 0.11
chr2_238887461_238887612 0.37 UBE2F
 ubiquitin-conjugating enzyme E2F (putative)
 5799
 0.22
chr21_33894297_33894448 0.37 ENSG00000252045
 .
 16237
 0.16
chr5_176869820_176870094 0.36 PRR7-AS1
 PRR7 antisense RNA 1
 1521
 0.22
chr16_57849254_57849515 0.36 CTD-2600O9.1
 uncharacterized protein LOC388282
 1700
 0.28
chr16_30081154_30081305 0.36 ALDOA
 aldolase A, fructose-bisphosphate
 330
 0.73
chr19_50289714_50289865 0.36 AP2A1
 adaptor-related protein complex 2, alpha 1 subunit
 19398
 0.06
chr15_99983240_99983408 0.36 MEF2A
 myocyte enhancer factor 2A
 34046
 0.15
chr2_120156492_120156643 0.36 TMEM37
 transmembrane protein 37
 30910
 0.14
chr8_141599068_141599368 0.36 AGO2
 argonaute RISC catalytic component 2
 16769
 0.22
chr1_27668239_27668429 0.36 SYTL1
 synaptotagmin-like 1
 179
 0.91
chr17_26832603_26832754 0.36 FOXN1
 forkhead box N1
 583
 0.59
chr22_46502171_46502327 0.35 ENSG00000198986
 .
 6380
 0.1
chr19_18596855_18597476 0.35 ELL
 elongation factor RNA polymerase II
 10422
 0.1
chr17_4641577_4641728 0.35 CXCL16
 chemokine (C-X-C motif) ligand 16
 788
 0.36
chr4_182887638_182887789 0.35 AC108142.1
118524
 0.06
chr8_11414885_11415154 0.35 RP11-148O21.4
512
 0.71
chr15_31657045_31657355 0.35 KLF13
 Kruppel-like factor 13
 1157
 0.65
chr6_54711184_54711335 0.35 FAM83B
 family with sequence similarity 83, member B
 310
 0.91
chr15_67400398_67400572 0.35 SMAD3
 SMAD family member 3
 9468
 0.25
chr12_109006057_109006234 0.35 TMEM119
 transmembrane protein 119
 14049
 0.12
chr11_3035348_3035499 0.35 CARS-AS1
 CARS antisense RNA 1
 15201
 0.11
chr5_172754453_172754739 0.35 STC2
 stanniocalcin 2
 460
 0.82
chr4_55099953_55100185 0.34 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
 3580
 0.33
chr15_75250496_75250705 0.34 RPP25
 ribonuclease P/MRP 25kDa subunit
 795
 0.51
chr21_43422027_43422309 0.34 ZBTB21
 zinc finger and BTB domain containing 21
 5998
 0.21
chr1_2345042_2345250 0.34 PEX10
 peroxisomal biogenesis factor 10
 90
 0.94
chr22_18916870_18917021 0.34 PRODH
 proline dehydrogenase (oxidase) 1
 5396
 0.18
chr3_182792190_182792488 0.34 MCCC1
 methylcrotonoyl-CoA carboxylase 1 (alpha)
 24967
 0.19
chr17_39496038_39496239 0.34 KRT33A
 keratin 33A
 10926
 0.08
chr1_44030870_44031021 0.34 PTPRF
 protein tyrosine phosphatase, receptor type, F
 20198
 0.18
chr1_25307860_25308011 0.34 RUNX3
 runt-related transcription factor 3
 16434
 0.19
chr11_67183978_67184499 0.34 CARNS1
 carnosine synthase 1
 681
 0.4
chr1_6647040_6647244 0.34 ZBTB48
 zinc finger and BTB domain containing 48
 6994
 0.12
chr19_30115060_30115211 0.34 POP4
 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
 17907
 0.21
chr19_11249778_11250050 0.34 SPC24
 SPC24, NDC80 kinetochore complex component
 16523
 0.12
chr11_2406504_2406655 0.34 CD81
 CD81 molecule
 317
 0.81
chr15_41244464_41244615 0.34 CHAC1
 ChaC, cation transport regulator homolog 1 (E. coli)
 621
 0.64
chr17_80196204_80196816 0.34 SLC16A3
 solute carrier family 16 (monocarboxylate transporter), member 3
 1464
 0.26
chr14_75039833_75039984 0.34 LTBP2
 latent transforming growth factor beta binding protein 2
 38867
 0.13
chr3_10975044_10975195 0.34 SLC6A1
 solute carrier family 6 (neurotransmitter transporter), member 1
 59291
 0.13
chr22_46447401_46447609 0.34 RP6-109B7.5
1468
 0.21
chr7_76236455_76236606 0.33 POMZP3
 POM121 and ZP3 fusion
 11087
 0.2
chr14_105437323_105437474 0.33 AHNAK2
 AHNAK nucleoprotein 2
 7296
 0.16
chr16_69515111_69515262 0.33 CYB5B
 cytochrome b5 type B (outer mitochondrial membrane)
 56500
 0.09
chr22_21335373_21335584 0.33 LZTR1
 leucine-zipper-like transcription regulator 1
 824
 0.39
chr1_2140834_2140985 0.33 AL590822.1
 Uncharacterized protein
 4711
 0.13
chr22_39633799_39634052 0.33 PDGFB
 platelet-derived growth factor beta polypeptide
 2989
 0.2
chr10_114394071_114394222 0.33 ENSG00000264763
 .
 217
 0.96
chr2_235406648_235406799 0.33 ARL4C
 ADP-ribosylation factor-like 4C
 1026
 0.71
chr16_31141784_31142119 0.33 RP11-388M20.2
803
 0.33
chr12_81471874_81472025 0.33 ACSS3
 acyl-CoA synthetase short-chain family member 3
 113
 0.98
chr1_20813373_20813524 0.33 CAMK2N1
 calcium/calmodulin-dependent protein kinase II inhibitor 1
 735
 0.68
chr8_139805893_139806044 0.33 COL22A1
 collagen, type XXII, alpha 1
 14163
 0.32
chr16_87270556_87270707 0.33 RP11-899L11.3
21110
 0.16
chr17_71820638_71820789 0.33 SDK2
 sidekick cell adhesion molecule 2
 180485
 0.03
chr6_12325038_12325189 0.33 EDN1
 endothelin 1
 34517
 0.22
chr17_74526070_74526300 0.33 CYGB
 cytoglobin
 1962
 0.16
chr17_39067227_39067378 0.32 AC004231.2
10380
 0.1
chrX_23919381_23919603 0.32 CXorf58
 chromosome X open reading frame 58
 6426
 0.2
chr7_28398441_28398592 0.32 CREB5
 cAMP responsive element binding protein 5
 50490
 0.18
chr21_42441104_42441255 0.32 LINC00323
 long intergenic non-protein coding RNA 323
 78171
 0.09
chr9_114736508_114736659 0.32 ENSG00000222356
 .
 22436
 0.17
chr3_45225003_45225154 0.32 CDCP1
 CUB domain containing protein 1
 37164
 0.15
chr14_102197077_102197344 0.32 RP11-796G6.2
 Uncharacterized protein
 436
 0.83
chr1_3390429_3390580 0.32 ARHGEF16
 Rho guanine nucleotide exchange factor (GEF) 16
 2316
 0.31
chr1_185703531_185703682 0.32 HMCN1
 hemicentin 1
 77
 0.98
chr7_55322085_55322386 0.32 EGFR-AS1
 EGFR antisense RNA 1
 65608
 0.13
chr8_101428189_101428340 0.32 ENSG00000265599
 .
 33273
 0.16
chr7_29663646_29663797 0.32 DPY19L2P3
 DPY19L2 pseudogene 3
 26122
 0.18
chr6_147828281_147828543 0.32 SAMD5
 sterile alpha motif domain containing 5
 1651
 0.55
chr9_137221477_137221979 0.32 RXRA
 retinoid X receptor, alpha
 3302
 0.32
chr1_19395472_19395623 0.32 UBR4
 ubiquitin protein ligase E3 component n-recognin 4
 13187
 0.19
chr17_41439641_41439819 0.31 ENSG00000188825
 .
 25055
 0.11
chr6_35048787_35048938 0.31 TCP11
 t-complex 11, testis-specific
 39960
 0.16
chr10_73869748_73870117 0.31 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 21142
 0.19
chr10_29768661_29768812 0.31 SVIL
 supervillin
 16711
 0.22
chr10_73769753_73769963 0.31 CHST3
 carbohydrate (chondroitin 6) sulfotransferase 3
 45735
 0.15
chr10_75494456_75494607 0.31 GLUD1P3
 glutamate dehydrogenase 1 pseudogene 3
 3597
 0.1
chr22_37809155_37809306 0.31 RP1-63G5.5
14250
 0.14
chr10_33624973_33625145 0.31 NRP1
 neuropilin 1
 131
 0.98
chr16_15235562_15235795 0.31 ENSG00000207294
 .
 8876
 0.11
chr22_37427155_37427306 0.31 MPST
 mercaptopyruvate sulfurtransferase
 8152
 0.1
chr4_1757359_1757510 0.31 TACC3
 transforming, acidic coiled-coil containing protein 3
 27303
 0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.6 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.6 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 0.3 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.9 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.2 GO:0048865 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.1 0.3 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.4 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.1 0.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.2 GO:0006562 proline catabolic process(GO:0006562)
0.1 0.2 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.1 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.1 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.4 GO:0034331 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.1 0.2 GO:0060014 granulosa cell differentiation(GO:0060014)
0.1 0.4 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.1 GO:0055089 fatty acid homeostasis(GO:0055089)
0.1 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.1 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.2 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.3 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.3 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.2 GO:0060534 trachea cartilage development(GO:0060534)
0.0 0.1 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.2 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.2 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.2 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.3 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.1 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988) negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.0 GO:0072162 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.3 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.6 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.0 GO:0060068 vagina development(GO:0060068)
0.0 0.2 GO:0051593 response to folic acid(GO:0051593)
0.0 0.1 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.2 GO:0090103 cochlea morphogenesis(GO:0090103)
0.0 0.1 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 0.1 GO:0046475 phosphatidylcholine catabolic process(GO:0034638) glycerophospholipid catabolic process(GO:0046475)
0.0 0.0 GO:0070141 response to UV-A(GO:0070141)
0.0 0.3 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0051583 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0045843 negative regulation of striated muscle tissue development(GO:0045843)
0.0 0.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.3 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.0 0.5 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.1 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.0 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.0 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0060581 ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.2 GO:0071453 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.0 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.0 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.2 GO:0043525 positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.0 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.0 GO:0010985 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) negative regulation of lipoprotein particle clearance(GO:0010985)
0.0 0.1 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.0 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.0 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0001676 long-chain fatty acid metabolic process(GO:0001676)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.0 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0048247 lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0 0.0 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.2 GO:0046676 negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.0 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.3 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.0 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.1 GO:0032096 negative regulation of response to food(GO:0032096)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0051492 regulation of stress fiber assembly(GO:0051492)
0.0 0.0 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.6 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.0 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0045123 cellular extravasation(GO:0045123)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.1 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.0 0.1 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.0 0.1 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.0 GO:0098810 neurotransmitter reuptake(GO:0098810)
0.0 0.2 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.0 GO:0021548 pons development(GO:0021548)
0.0 0.0 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0010288 response to lead ion(GO:0010288)
0.0 0.2 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.0 0.0 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0051828 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.0 GO:0060192 negative regulation of lipase activity(GO:0060192)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.0 GO:1903019 negative regulation of glycoprotein metabolic process(GO:1903019)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.0 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0009267 cellular response to starvation(GO:0009267)
0.0 0.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.0 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.0 GO:0048302 regulation of isotype switching to IgG isotypes(GO:0048302)
0.0 0.2 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.1 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 0.0 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.1 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.4 GO:0042825 TAP complex(GO:0042825)
0.1 0.6 GO:0002102 podosome(GO:0002102)
0.1 0.2 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.2 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.0 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.0 GO:0071547 piP-body(GO:0071547)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.0 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0042581 specific granule(GO:0042581)
0.0 0.6 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.4 GO:0046980 tapasin binding(GO:0046980)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.3 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.8 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.2 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.1 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.4 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 1.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.8 GO:0051117 ATPase binding(GO:0051117)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0051192 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.1 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.1 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.4 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0 0.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.0 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.0 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.2 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.0 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.0 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.0 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.0 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0042809 vitamin D receptor binding(GO:0042809)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.0 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.0 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.0 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions