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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TFAP2B

Z-value: 1.60

Motif logo

Transcription factors associated with TFAP2B

Gene Symbol	Gene ID	Gene Info
TFAP2B Ensembl NCBI GeneCards UniProt	ENSG00000008196.8	TFAP2B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
TFAP2B	chr6_50783493_50783702	2839	0.410011	-0.82	6.2e-03	Click!
TFAP2B	chr6_50903539_50903690	117175	0.068877	-0.79	1.2e-02	Click!
TFAP2B	chr6_50929546_50929733	143200	0.049753	-0.76	1.7e-02	Click!
TFAP2B	chr6_50929115_50929282	142759	0.050012	-0.69	3.9e-02	Click!
TFAP2B	chr6_50789163_50789314	2799	0.414549	0.69	4.1e-02	Click!

Activity of the TFAP2B motif across conditions

Conditions sorted by the z-value of the TFAP2B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_228336809_228337095	1.19	GJC2	gap junction protein, gamma 2, 47kDa	601	0.58
chr9_133302644_133302795	0.80	HMCN2	hemicentin 2	2950	0.21
chr10_112168315_112168466	0.70	ENSG00000221359	.	25609	0.19
chr7_4771612_4771763	0.67	FOXK1	forkhead box K1	8803	0.19
chr19_4713192_4713546	0.67	DPP9	dipeptidyl-peptidase 9	949	0.43
chr15_74679279_74679430	0.66	CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	19273	0.13
chr17_78933014_78933165	0.66	CTD-2561B21.3		2424	0.18
chr10_88409177_88409328	0.65	OPN4	opsin 4	5062	0.22
chr6_37666285_37666474	0.63	MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	613	0.81
chr9_36859555_36859706	0.63	RP11-344B23.2		3078	0.23
chr14_105445324_105445475	0.63	AHNAK2	AHNAK nucleoprotein 2	705	0.63
chr4_6272197_6272532	0.62	WFS1	Wolfram syndrome 1 (wolframin)	787	0.74
chr20_31384666_31384857	0.62	DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	17103	0.16
chr12_124907481_124907632	0.61	NCOR2	nuclear receptor corepressor 2	34186	0.22
chr6_106590141_106590398	0.61	RP1-134E15.3		42254	0.16
chr14_99714170_99714435	0.61	AL109767.1		14983	0.21
chr22_20226986_20227137	0.59	RTN4R	reticulon 4 receptor	4146	0.16
chr11_64609797_64609948	0.58	CDC42BPG	CDC42 binding protein kinase gamma (DMPK-like)	2169	0.18
chr22_29705214_29705587	0.58	GAS2L1	growth arrest-specific 2 like 1	2352	0.17
chr4_3439247_3439398	0.57	HGFAC	HGF activator	4292	0.21
chr16_70774609_70775132	0.56	VAC14	Vac14 homolog (S. cerevisiae)	3613	0.18
chr1_19338582_19338733	0.56	IFFO2	intermediate filament family orphan 2	55477	0.11
chr11_3109293_3109444	0.55	OSBPL5	oxysterol binding protein-like 5	6741	0.16
chr9_101573597_101573748	0.55	GALNT12	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)	3691	0.24
chr10_95229262_95229590	0.55	MYOF	myoferlin	12525	0.19
chr1_193155079_193155230	0.54	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	630	0.75
chr20_60945069_60945220	0.53	LAMA5	laminin, alpha 5	2776	0.17
chr9_131675686_131675837	0.53	PHYHD1	phytanoyl-CoA dioxygenase domain containing 1	7413	0.12
chr8_124553954_124554105	0.53	FBXO32	F-box protein 32	583	0.77
chr5_175257162_175257313	0.52	CPLX2	complexin 2	31394	0.18
chr3_55525759_55525910	0.52	WNT5A	wingless-type MMTV integration site family, member 5A	1861	0.41
chr18_77937535_77937686	0.52	AC139100.3		3953	0.23
chr10_5567726_5567877	0.52	RP11-116G8.5		96	0.8
chr3_128016629_128016780	0.51	ENSG00000221067	.	64304	0.11
chr9_140507478_140507731	0.51	C9orf37	chromosome 9 open reading frame 37	5661	0.12
chr10_5605742_5605953	0.51	CALML3-AS1	CALML3 antisense RNA 1	37638	0.11
chr12_123555934_123556085	0.50	PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2	4633	0.2
chr21_45715243_45715525	0.50	PFKL	phosphofructokinase, liver	4550	0.11
chr1_6419961_6420398	0.50	ACOT7	acyl-CoA thioesterase 7	587	0.69
chr15_45455194_45455384	0.50	RP11-519G16.2		7253	0.1
chr16_85388240_85388391	0.49	RP11-680G10.1	Uncharacterized protein	2754	0.33
chr12_94441922_94442073	0.48	ENSG00000223126	.	39174	0.18
chr18_47205073_47205224	0.48	LIPG	lipase, endothelial	116433	0.04
chr14_68935288_68935439	0.48	RAD51B	RAD51 paralog B	57136	0.15
chr3_159505193_159505344	0.48	IQCJ-SCHIP1-AS1	IQCJ-SCHIP1 readthrough antisense RNA 1	18867	0.15
chr12_52546716_52546867	0.47	KRT80	keratin 80	38993	0.08
chr15_74472280_74472489	0.47	RP11-665J16.1		817	0.48
chr4_6274602_6274753	0.47	WFS1	Wolfram syndrome 1 (wolframin)	3100	0.35
chr7_130003657_130003904	0.46	CPA5	carboxypeptidase A5	498	0.72
chr14_102172572_102172843	0.46	RP11-796G6.2	Uncharacterized protein	24067	0.17
chr14_32414488_32414678	0.46	RP11-187E13.1	Uncharacterized protein	524	0.84
chr6_116772654_116772805	0.46	ENSG00000265516	.	6256	0.14
chr4_2801177_2801328	0.46	SH3BP2	SH3-domain binding protein 2	527	0.8
chr7_1562610_1562761	0.45	MAFK	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K	7665	0.14
chr7_73120336_73120487	0.45	ENSG00000265724	.	5236	0.11
chr12_123429411_123429620	0.45	ABCB9	ATP-binding cassette, sub-family B (MDR/TAP), member 9	293	0.88
chr1_26217938_26218089	0.45	STMN1	stathmin 1	13606	0.08
chr3_42556058_42556209	0.45	VIPR1	vasoactive intestinal peptide receptor 1	12018	0.15
chr11_118492770_118493048	0.45	AP002954.3		14429	0.11
chr16_57831186_57831470	0.45	KIFC3	kinesin family member C3	348	0.84
chr2_87842171_87842497	0.44	RP11-1399P15.1		64781	0.13
chr11_94480509_94480660	0.44	RP11-867G2.8		7063	0.23
chr14_23011383_23011534	0.44	TRAJ15	T cell receptor alpha joining 15	12878	0.1
chr2_73297957_73298126	0.44	SFXN5	sideroflexin 5	761	0.67
chr17_38600137_38600500	0.44	IGFBP4	insulin-like growth factor binding protein 4	605	0.66
chr7_966993_967144	0.43	ADAP1	ArfGAP with dual PH domains 1	82	0.96
chr19_4584744_4584943	0.43	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	25023	0.09
chr14_104321166_104321317	0.43	PPP1R13B	protein phosphatase 1, regulatory subunit 13B	7314	0.17
chr14_100040999_100041176	0.43	CCDC85C	coiled-coil domain containing 85C	1775	0.33
chr19_49119290_49119441	0.43	FAM83E	family with sequence similarity 83, member E	1293	0.21
chr1_43415164_43415399	0.42	SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	9219	0.19
chr12_3228682_3229088	0.42	TSPAN9-IT1	TSPAN9 intronic transcript 1 (non-protein coding)	30078	0.18
chr7_150635354_150635936	0.42	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2	17349	0.15
chr2_113392435_113392586	0.42	SLC20A1	solute carrier family 20 (phosphate transporter), member 1	10924	0.19
chr4_6274786_6274937	0.42	WFS1	Wolfram syndrome 1 (wolframin)	3284	0.34
chr2_97561253_97561466	0.42	FAM178B	family with sequence similarity 178, member B	2511	0.22
chr16_68278720_68278897	0.42	PLA2G15	phospholipase A2, group XV	399	0.66
chr17_41938860_41939011	0.42	CD300LG	CD300 molecule-like family member g	14391	0.11
chr1_8255073_8255224	0.42	ENSG00000200975	.	11509	0.23
chr2_111367449_111367600	0.42	AC123886.2		969	0.61
chr2_219472098_219472249	0.42	PLCD4	phospholipase C, delta 4	315	0.8
chr7_99760518_99760936	0.42	GAL3ST4	galactose-3-O-sulfotransferase 4	4126	0.07
chr2_98964621_98964860	0.42	AC092675.4		1282	0.37
chr17_79856034_79856185	0.41	NPB	neuropeptide B	2512	0.09
chr22_20229537_20229756	0.41	RTN4R	reticulon 4 receptor	1561	0.29
chr16_51189445_51189596	0.41	SALL1	spalt-like transcription factor 1	4334	0.27
chr15_84048823_84048974	0.41	SH3GL3	SH3-domain GRB2-like 3	67082	0.11
chr11_133818315_133818530	0.41	IGSF9B	immunoglobulin superfamily, member 9B	2235	0.31
chr21_45502719_45503242	0.41	PWP2	PWP2 periodic tryptophan protein homolog (yeast)	24191	0.15
chr2_133173738_133173889	0.41	GPR39	G protein-coupled receptor 39	334	0.9
chr15_76488697_76488848	0.41	RP11-593F23.1		14945	0.24
chr19_38879548_38879838	0.40	SPRED3	sprouty-related, EVH1 domain containing 3	559	0.46
chr10_116267845_116267996	0.40	ABLIM1	actin binding LIM protein 1	18674	0.24
chr1_210405648_210405799	0.40	SERTAD4	SERTA domain containing 4	421	0.6
chr16_811264_811437	0.40	MSLN	mesothelin	252	0.78
chr6_37592095_37592288	0.39	MDGA1	MAM domain containing glycosylphosphatidylinositol anchor 1	21959	0.22
chr10_80918331_80918482	0.39	ZMIZ1	zinc finger, MIZ-type containing 1	89614	0.09
chr5_31988023_31988174	0.39	ENSG00000266243	.	51833	0.13
chr2_235932870_235933072	0.39	SH3BP4	SH3-domain binding protein 4	29487	0.26
chr2_69534306_69534473	0.39	ENSG00000252250	.	27343	0.2
chr2_28977323_28977503	0.39	PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme	2694	0.24
chr12_112195610_112195963	0.39	RP11-162P23.2		4092	0.21
chr1_47077504_47077655	0.38	MOB3C	MOB kinase activator 3C	3226	0.18
chr20_61468104_61468255	0.38	COL9A3	collagen, type IX, alpha 3	19016	0.11
chr15_80472063_80472219	0.38	FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)	23848	0.2
chr20_60892338_60892489	0.38	RP11-157P1.4		11032	0.12
chr1_156631459_156631667	0.38	RP11-284F21.7		347	0.75
chr11_112411093_112411244	0.38	ENSG00000212397	.	62007	0.14
chr6_160399730_160400221	0.38	IGF2R	insulin-like growth factor 2 receptor	9844	0.21
chr3_33033448_33033599	0.38	CCR4	chemokine (C-C motif) receptor 4	40457	0.16
chr13_95898574_95898725	0.37	ENSG00000238463	.	36051	0.17
chr2_110519060_110519211	0.37	RGPD5	RANBP2-like and GRIP domain containing 5	31200	0.22
chr4_147443936_147444348	0.37	SLC10A7	solute carrier family 10, member 7	1019	0.64
chr1_19255265_19255716	0.37	IFFO2	intermediate filament family orphan 2	17004	0.16
chr7_578321_578511	0.37	ENSG00000252986	.	11954	0.17
chr11_66137353_66137504	0.37	SLC29A2	solute carrier family 29 (equilibrative nucleoside transporter), member 2	1863	0.14
chr17_79386944_79387260	0.37	ENSG00000266392	.	12524	0.11
chr2_238887461_238887612	0.37	UBE2F	ubiquitin-conjugating enzyme E2F (putative)	5799	0.22
chr21_33894297_33894448	0.37	ENSG00000252045	.	16237	0.16
chr5_176869820_176870094	0.36	PRR7-AS1	PRR7 antisense RNA 1	1521	0.22
chr16_57849254_57849515	0.36	CTD-2600O9.1	uncharacterized protein LOC388282	1700	0.28
chr16_30081154_30081305	0.36	ALDOA	aldolase A, fructose-bisphosphate	330	0.73
chr19_50289714_50289865	0.36	AP2A1	adaptor-related protein complex 2, alpha 1 subunit	19398	0.06
chr15_99983240_99983408	0.36	MEF2A	myocyte enhancer factor 2A	34046	0.15
chr2_120156492_120156643	0.36	TMEM37	transmembrane protein 37	30910	0.14
chr8_141599068_141599368	0.36	AGO2	argonaute RISC catalytic component 2	16769	0.22
chr1_27668239_27668429	0.36	SYTL1	synaptotagmin-like 1	179	0.91
chr17_26832603_26832754	0.36	FOXN1	forkhead box N1	583	0.59
chr22_46502171_46502327	0.35	ENSG00000198986	.	6380	0.1
chr19_18596855_18597476	0.35	ELL	elongation factor RNA polymerase II	10422	0.1
chr17_4641577_4641728	0.35	CXCL16	chemokine (C-X-C motif) ligand 16	788	0.36
chr4_182887638_182887789	0.35	AC108142.1		118524	0.06
chr8_11414885_11415154	0.35	RP11-148O21.4		512	0.71
chr15_31657045_31657355	0.35	KLF13	Kruppel-like factor 13	1157	0.65
chr6_54711184_54711335	0.35	FAM83B	family with sequence similarity 83, member B	310	0.91
chr15_67400398_67400572	0.35	SMAD3	SMAD family member 3	9468	0.25
chr12_109006057_109006234	0.35	TMEM119	transmembrane protein 119	14049	0.12
chr11_3035348_3035499	0.35	CARS-AS1	CARS antisense RNA 1	15201	0.11
chr5_172754453_172754739	0.35	STC2	stanniocalcin 2	460	0.82
chr4_55099953_55100185	0.34	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	3580	0.33
chr15_75250496_75250705	0.34	RPP25	ribonuclease P/MRP 25kDa subunit	795	0.51
chr21_43422027_43422309	0.34	ZBTB21	zinc finger and BTB domain containing 21	5998	0.21
chr1_2345042_2345250	0.34	PEX10	peroxisomal biogenesis factor 10	90	0.94
chr22_18916870_18917021	0.34	PRODH	proline dehydrogenase (oxidase) 1	5396	0.18
chr3_182792190_182792488	0.34	MCCC1	methylcrotonoyl-CoA carboxylase 1 (alpha)	24967	0.19
chr17_39496038_39496239	0.34	KRT33A	keratin 33A	10926	0.08
chr1_44030870_44031021	0.34	PTPRF	protein tyrosine phosphatase, receptor type, F	20198	0.18
chr1_25307860_25308011	0.34	RUNX3	runt-related transcription factor 3	16434	0.19
chr11_67183978_67184499	0.34	CARNS1	carnosine synthase 1	681	0.4
chr1_6647040_6647244	0.34	ZBTB48	zinc finger and BTB domain containing 48	6994	0.12
chr19_30115060_30115211	0.34	POP4	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)	17907	0.21
chr19_11249778_11250050	0.34	SPC24	SPC24, NDC80 kinetochore complex component	16523	0.12
chr11_2406504_2406655	0.34	CD81	CD81 molecule	317	0.81
chr15_41244464_41244615	0.34	CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	621	0.64
chr17_80196204_80196816	0.34	SLC16A3	solute carrier family 16 (monocarboxylate transporter), member 3	1464	0.26
chr14_75039833_75039984	0.34	LTBP2	latent transforming growth factor beta binding protein 2	38867	0.13
chr3_10975044_10975195	0.34	SLC6A1	solute carrier family 6 (neurotransmitter transporter), member 1	59291	0.13
chr22_46447401_46447609	0.34	RP6-109B7.5		1468	0.21
chr7_76236455_76236606	0.33	POMZP3	POM121 and ZP3 fusion	11087	0.2
chr14_105437323_105437474	0.33	AHNAK2	AHNAK nucleoprotein 2	7296	0.16
chr16_69515111_69515262	0.33	CYB5B	cytochrome b5 type B (outer mitochondrial membrane)	56500	0.09
chr22_21335373_21335584	0.33	LZTR1	leucine-zipper-like transcription regulator 1	824	0.39
chr1_2140834_2140985	0.33	AL590822.1	Uncharacterized protein	4711	0.13
chr22_39633799_39634052	0.33	PDGFB	platelet-derived growth factor beta polypeptide	2989	0.2
chr10_114394071_114394222	0.33	ENSG00000264763	.	217	0.96
chr2_235406648_235406799	0.33	ARL4C	ADP-ribosylation factor-like 4C	1026	0.71
chr16_31141784_31142119	0.33	RP11-388M20.2		803	0.33
chr12_81471874_81472025	0.33	ACSS3	acyl-CoA synthetase short-chain family member 3	113	0.98
chr1_20813373_20813524	0.33	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1	735	0.68
chr8_139805893_139806044	0.33	COL22A1	collagen, type XXII, alpha 1	14163	0.32
chr16_87270556_87270707	0.33	RP11-899L11.3		21110	0.16
chr17_71820638_71820789	0.33	SDK2	sidekick cell adhesion molecule 2	180485	0.03
chr6_12325038_12325189	0.33	EDN1	endothelin 1	34517	0.22
chr17_74526070_74526300	0.33	CYGB	cytoglobin	1962	0.16
chr17_39067227_39067378	0.32	AC004231.2		10380	0.1
chrX_23919381_23919603	0.32	CXorf58	chromosome X open reading frame 58	6426	0.2
chr7_28398441_28398592	0.32	CREB5	cAMP responsive element binding protein 5	50490	0.18
chr21_42441104_42441255	0.32	LINC00323	long intergenic non-protein coding RNA 323	78171	0.09
chr9_114736508_114736659	0.32	ENSG00000222356	.	22436	0.17
chr3_45225003_45225154	0.32	CDCP1	CUB domain containing protein 1	37164	0.15
chr14_102197077_102197344	0.32	RP11-796G6.2	Uncharacterized protein	436	0.83
chr1_3390429_3390580	0.32	ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16	2316	0.31
chr1_185703531_185703682	0.32	HMCN1	hemicentin 1	77	0.98
chr7_55322085_55322386	0.32	EGFR-AS1	EGFR antisense RNA 1	65608	0.13
chr8_101428189_101428340	0.32	ENSG00000265599	.	33273	0.16
chr7_29663646_29663797	0.32	DPY19L2P3	DPY19L2 pseudogene 3	26122	0.18
chr6_147828281_147828543	0.32	SAMD5	sterile alpha motif domain containing 5	1651	0.55
chr9_137221477_137221979	0.32	RXRA	retinoid X receptor, alpha	3302	0.32
chr1_19395472_19395623	0.32	UBR4	ubiquitin protein ligase E3 component n-recognin 4	13187	0.19
chr17_41439641_41439819	0.31	ENSG00000188825	.	25055	0.11
chr6_35048787_35048938	0.31	TCP11	t-complex 11, testis-specific	39960	0.16
chr10_73869748_73870117	0.31	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	21142	0.19
chr10_29768661_29768812	0.31	SVIL	supervillin	16711	0.22
chr10_73769753_73769963	0.31	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	45735	0.15
chr10_75494456_75494607	0.31	GLUD1P3	glutamate dehydrogenase 1 pseudogene 3	3597	0.1
chr22_37809155_37809306	0.31	RP1-63G5.5		14250	0.14
chr10_33624973_33625145	0.31	NRP1	neuropilin 1	131	0.98
chr16_15235562_15235795	0.31	ENSG00000207294	.	8876	0.11
chr22_37427155_37427306	0.31	MPST	mercaptopyruvate sulfurtransferase	8152	0.1
chr4_1757359_1757510	0.31	TACC3	transforming, acidic coiled-coil containing protein 3	27303	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2B

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1	0.6	GO:0008218	bioluminescence(GO:0008218)
0.1	0.4	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.6	GO:0022417	protein maturation by protein folding(GO:0022417)
0.1	0.3	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.2	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.9	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.1	0.2	GO:0048865	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.1	0.3	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.4	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.1	0.2	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.1	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.2	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.2	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.1	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.1	0.2	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.4	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.1	0.2	GO:0060014	granulosa cell differentiation(GO:0060014)
0.1	0.4	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1	0.1	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.1	0.2	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1	0.2	GO:0046548	retinal rod cell development(GO:0046548)
0.1	0.1	GO:0060424	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1	0.2	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	0.2	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	0.5	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.2	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.2	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0001865	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.3	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.3	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.2	GO:0060534	trachea cartilage development(GO:0060534)
0.0	0.1	GO:0072033	renal vesicle formation(GO:0072033)
0.0	0.1	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.2	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.2	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.2	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.3	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988) negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.0	GO:0072162	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.1	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.3	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.6	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.1	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.1	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.2	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.2	GO:0051593	response to folic acid(GO:0051593)
0.0	0.1	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.1	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.2	GO:0090103	cochlea morphogenesis(GO:0090103)
0.0	0.1	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.1	GO:0046475	phosphatidylcholine catabolic process(GO:0034638) glycerophospholipid catabolic process(GO:0046475)
0.0	0.0	GO:0070141	response to UV-A(GO:0070141)
0.0	0.3	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.1	GO:0051583	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.3	GO:1903963	arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.0	0.0	GO:0032415	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.2	GO:0045843	negative regulation of striated muscle tissue development(GO:0045843)
0.0	0.1	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.3	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.5	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.2	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.2	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.0	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.2	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.0	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.0	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.1	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.4	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.2	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.0	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0060581	ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.2	GO:0071453	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0048266	behavioral response to pain(GO:0048266)
0.0	0.2	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.1	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.1	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.2	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.0	GO:0090312	positive regulation of protein deacetylation(GO:0090312)
0.0	0.0	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.1	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0031958	corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.2	GO:0043525	positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0060058	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.1	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.0	GO:0010985	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) negative regulation of lipoprotein particle clearance(GO:0010985)
0.0	0.1	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.1	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.0	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226) positive regulation of dopamine secretion(GO:0033603)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.2	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.2	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.1	GO:0001676	long-chain fatty acid metabolic process(GO:0001676)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.0	GO:0051531	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0015858	nucleoside transport(GO:0015858)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0048247	lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0	0.0	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.3	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.2	GO:0046676	negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.0	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.3	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.2	GO:0090003	regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.1	GO:0032096	negative regulation of response to food(GO:0032096)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0051492	regulation of stress fiber assembly(GO:0051492)
0.0	0.0	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.0	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.1	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.6	GO:0009062	fatty acid catabolic process(GO:0009062)
0.0	0.0	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.0	0.1	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.0	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:0045123	cellular extravasation(GO:0045123)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.4	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0051852	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0	0.1	GO:0051445	regulation of meiotic cell cycle(GO:0051445)
0.0	0.1	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	0.1	GO:0048679	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.0	GO:0098810	neurotransmitter reuptake(GO:0098810)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0021548	pons development(GO:0021548)
0.0	0.0	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.2	GO:0050771	negative regulation of axonogenesis(GO:0050771)
0.0	0.0	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0051828	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.0	GO:0060192	negative regulation of lipase activity(GO:0060192)
0.0	0.0	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.0	GO:1903019	negative regulation of glycoprotein metabolic process(GO:1903019)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0009267	cellular response to starvation(GO:0009267)
0.0	0.2	GO:0001578	microtubule bundle formation(GO:0001578)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.0	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.0	GO:0072070	loop of Henle development(GO:0072070)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0055012	ventricular cardiac muscle cell differentiation(GO:0055012)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.1	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.0	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.0	GO:0048302	regulation of isotype switching to IgG isotypes(GO:0048302)
0.0	0.2	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.1	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0016180	snRNA processing(GO:0016180)
0.0	0.0	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.0	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.2	GO:0030010	establishment of cell polarity(GO:0030010)
0.0	0.0	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.0	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.1	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.4	GO:0042825	TAP complex(GO:0042825)
0.1	0.6	GO:0002102	podosome(GO:0002102)
0.1	0.2	GO:0043260	laminin-11 complex(GO:0043260)
0.1	0.2	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	0.2	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.2	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.2	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.2	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.8	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.4	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.5	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	1.1	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.2	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.3	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.3	GO:0005771	multivesicular body(GO:0005771)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.0	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.0	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.0	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0005858	axonemal dynein complex(GO:0005858)
0.0	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.0	GO:0071547	piP-body(GO:0071547)
0.0	1.3	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.2	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.6	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0071564	npBAF complex(GO:0071564)
0.0	0.0	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.0	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.6	GO:0030496	midbody(GO:0030496)
0.0	0.4	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.4	GO:0046980	tapasin binding(GO:0046980)
0.1	0.3	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.3	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.1	0.3	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.5	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.3	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.3	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1	0.4	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.8	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.2	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.2	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.4	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.4	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	1.2	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.2	GO:0015185	gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.2	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.8	GO:0051117	ATPase binding(GO:0051117)
0.0	0.2	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.5	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.6	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0051192	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.1	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.4	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.3	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.3	GO:0030552	cAMP binding(GO:0030552)
0.0	0.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.2	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0022829	wide pore channel activity(GO:0022829)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.2	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.2	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.4	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0	0.2	GO:0005109	frizzled binding(GO:0005109)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.1	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.0	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.2	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.0	GO:0042806	fucose binding(GO:0042806)
0.0	0.1	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.2	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.4	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.0	0.1	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.2	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.0	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.0	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.0	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.0	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.0	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.2	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.0	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.0	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0004180	carboxypeptidase activity(GO:0004180)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.4	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.7	PID RAS PATHWAY	Regulation of Ras family activation
0.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.2	ST STAT3 PATHWAY	STAT3 Pathway
0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.3	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.5	ST G ALPHA I PATHWAY	G alpha i Pathway
0.5	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.4	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.4	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.5	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.1	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.3	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.9	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.3	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.4	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.2	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions