Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for TFAP2E

Z-value: 1.13

Motif logo

logo of

Transcription factors associated with TFAP2E

Gene Symbol Gene ID Gene Info
TFAP2E
ENSG00000116819.6 transcription factor AP-2 epsilon

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_36034994_36035145TFAP2E39020.1633290.872.2e-03Click!
chr1_36035927_36036078TFAP2E29690.1827360.703.5e-02Click!
chr1_36038348_36038499TFAP2E5480.5667190.373.2e-01Click!
chr1_36035265_36035416TFAP2E36310.1676710.373.3e-01Click!
chr1_36038695_36039018TFAP2E1150.8449280.039.3e-01Click!

Activity of the TFAP2E motif across conditions

Conditions sorted by the z-value of the TFAP2E motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_127489904_127490214 0.80 MGLL
 monoglyceride lipase
 12792
 0.24
chr7_155377735_155377886 0.64 CNPY1
 canopy FGF signaling regulator 1
 51253
 0.12
chr10_18071932_18072083 0.63 MRC1
 mannose receptor, C type 1
 26345
 0.17
chr2_238783166_238783317 0.57 ENSG00000263723
 .
 4694
 0.22
chr20_16507696_16507995 0.55 KIF16B
 kinesin family member 16B
 46233
 0.18
chr8_96237601_96237983 0.54 C8orf37
 chromosome 8 open reading frame 37
 43637
 0.17
chr20_33166706_33166857 0.53 MAP1LC3A
 microtubule-associated protein 1 light chain 3 alpha
 20259
 0.16
chr10_96974401_96974606 0.53 RP11-310E22.4
16398
 0.21
chr10_104539691_104539842 0.52 WBP1L
 WW domain binding protein 1-like
 3760
 0.18
chr2_69034764_69034964 0.50 ARHGAP25
 Rho GTPase activating protein 25
 501
 0.82
chr8_8269357_8269508 0.49 SGK223
 Tyrosine-protein kinase SgK223
 25424
 0.23
chr15_85215324_85215475 0.49 NMB
 neuromedin B
 13605
 0.1
chr2_9815348_9815499 0.48 YWHAQ
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
 44280
 0.14
chr9_136741627_136741778 0.47 VAV2
 vav 2 guanine nucleotide exchange factor
 115701
 0.05
chr12_122519590_122520270 0.47 MLXIP
 MLX interacting protein
 3302
 0.29
chr17_27910417_27910568 0.46 GIT1
 G protein-coupled receptor kinase interacting ArfGAP 1
 398
 0.68
chr15_44205800_44205951 0.46 FRMD5
 FERM domain containing 5
 5825
 0.19
chr4_5638816_5638967 0.45 EVC2
 Ellis van Creveld syndrome 2
 71403
 0.11
chr5_92629860_92630011 0.45 ENSG00000237187
 .
 128184
 0.06
chr2_40662476_40662683 0.45 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
 5135
 0.35
chr2_153406171_153406322 0.44 FMNL2
 formin-like 2
 69846
 0.13
chr1_118644337_118644488 0.43 SPAG17
 sperm associated antigen 17
 83434
 0.1
chr2_102680238_102680787 0.43 IL1R1
 interleukin 1 receptor, type I
 492
 0.85
chr8_143762185_143762336 0.42 PSCA
 prostate stem cell antigen
 385
 0.77
chr15_72487652_72487940 0.42 GRAMD2
 GRAM domain containing 2
 2330
 0.25
chr14_65703391_65703542 0.41 ENSG00000266740
 .
 98435
 0.07
chr5_81661345_81661496 0.40 ATP6AP1L
 ATPase, H+ transporting, lysosomal accessory protein 1-like
 60254
 0.15
chr19_8053652_8053803 0.39 ELAVL1
 ELAV like RNA binding protein 1
 7731
 0.11
chr12_32242647_32242798 0.39 BICD1
 bicaudal D homolog 1 (Drosophila)
 17047
 0.21
chr8_124468816_124468967 0.39 WDYHV1
 WDYHV motif containing 1
 26656
 0.16
chr7_155049692_155049843 0.39 INSIG1
 insulin induced gene 1
 39719
 0.15
chr2_112255788_112255939 0.39 ENSG00000266139
 .
 177195
 0.03
chr5_110789980_110790131 0.39 STARD4-AS1
 STARD4 antisense RNA 1
 57869
 0.12
chr1_110598662_110598813 0.39 RP4-773N10.4
2225
 0.21
chr17_47786040_47786409 0.38 SLC35B1
 solute carrier family 35, member B1
 152
 0.82
chr16_70414605_70414756 0.38 RP11-529K1.4
1320
 0.31
chr3_54925868_54926132 0.37 CACNA2D3-AS1
 CACNA2D3 antisense RNA 1
 9282
 0.27
chr7_137564480_137564636 0.37 DGKI
 diacylglycerol kinase, iota
 32720
 0.18
chr11_27444813_27444964 0.37 RP11-159H22.2
48388
 0.12
chr6_11212735_11212977 0.36 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 20035
 0.2
chr15_67316146_67316685 0.36 SMAD3
 SMAD family member 3
 39686
 0.2
chr1_211665583_211665734 0.35 RD3
 retinal degeneration 3
 601
 0.8
chr12_112550183_112550334 0.35 NAA25
 N(alpha)-acetyltransferase 25, NatB auxiliary subunit
 3432
 0.18
chr19_14669270_14669558 0.35 TECR
 trans-2,3-enoyl-CoA reductase
 3365
 0.13
chr22_38531557_38531708 0.35 PLA2G6
 phospholipase A2, group VI (cytosolic, calcium-independent)
 2748
 0.19
chr19_4712858_4713009 0.35 DPP9
 dipeptidyl-peptidase 9
 1385
 0.3
chr5_167243493_167243835 0.34 ENSG00000221741
 .
 54006
 0.13
chr2_216783049_216783200 0.34 ENSG00000212055
 .
 39482
 0.19
chr12_3231998_3232272 0.34 TSPAN9-IT1
 TSPAN9 intronic transcript 1 (non-protein coding)
 26828
 0.19
chr4_185739235_185739386 0.33 RP11-701P16.2
 Uncharacterized protein
 4537
 0.2
chr1_179096650_179096926 0.33 ABL2
 c-abl oncogene 2, non-receptor tyrosine kinase
 15391
 0.19
chr11_111794694_111794845 0.33 CRYAB
 crystallin, alpha B
 323
 0.78
chr15_31898343_31898494 0.33 OTUD7A
 OTU domain containing 7A
 49124
 0.19
chr10_79152930_79153197 0.33 KCNMA1
 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
 10679
 0.24
chr1_17519325_17519476 0.33 PADI1
 peptidyl arginine deiminase, type I
 12221
 0.17
chr4_55529764_55530043 0.33 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
 5818
 0.34
chr2_20777848_20777999 0.33 HS1BP3-IT1
 HS1BP3 intronic transcript 1 (non-protein coding)
 14385
 0.21
chr4_142273560_142273938 0.33 ENSG00000238695
 .
 54717
 0.16
chr4_78783004_78783324 0.32 MRPL1
 mitochondrial ribosomal protein L1
 510
 0.86
chr5_148349011_148349162 0.32 RP11-44B19.1
817
 0.67
chr10_116154509_116154660 0.32 AFAP1L2
 actin filament associated protein 1-like 2
 9655
 0.23
chr2_164538752_164538903 0.32 FIGN
 fidgetin
 53690
 0.19
chr5_9048002_9048358 0.32 ENSG00000266415
 .
 5827
 0.3
chrX_14977641_14977792 0.31 MOSPD2
 motile sperm domain containing 2
 50672
 0.17
chr17_70461708_70461859 0.31 ENSG00000200783
 .
 198508
 0.03
chr11_124770110_124770261 0.31 ROBO4
 roundabout, axon guidance receptor, homolog 4 (Drosophila)
 2008
 0.19
chr1_161171729_161171880 0.31 NDUFS2
 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
 133
 0.88
chr2_159779762_159779913 0.31 ENSG00000222300
 .
 12660
 0.2
chr1_239620290_239620441 0.31 CHRM3
 cholinergic receptor, muscarinic 3
 172008
 0.04
chr1_115782386_115782537 0.31 RP4-663N10.1
43194
 0.18
chr17_34112154_34112305 0.30 MMP28
 matrix metallopeptidase 28
 5857
 0.11
chr18_20862079_20862230 0.30 RP11-17J14.2
21836
 0.23
chr1_213293309_213293460 0.30 RPS6KC1
 ribosomal protein S6 kinase, 52kDa, polypeptide 1
 68780
 0.12
chrX_118628293_118628444 0.30 SLC25A5
 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
 26005
 0.12
chr3_149290093_149290244 0.30 WWTR1
 WW domain containing transcription regulator 1
 3871
 0.25
chr19_13171036_13171187 0.30 AC007787.2
11077
 0.1
chr16_75282266_75282417 0.30 BCAR1
 breast cancer anti-estrogen resistance 1
 203
 0.92
chr20_39122912_39123063 0.30 ENSG00000252434
 .
 77472
 0.12
chr6_14716899_14717050 0.30 ENSG00000206960
 .
 70208
 0.14
chr8_126668851_126669002 0.30 ENSG00000266452
 .
 212119
 0.02
chr1_24691365_24691516 0.29 STPG1
 sperm-tail PG-rich repeat containing 1
 14873
 0.16
chr11_78494593_78494744 0.29 TENM4
 teneurin transmembrane protein 4
 21788
 0.22
chr1_161052827_161053090 0.29 RP11-544M22.8
1297
 0.22
chr11_119189693_119189895 0.29 MCAM
 melanoma cell adhesion molecule
 1968
 0.16
chr1_45990852_45991003 0.29 PRDX1
 peroxiredoxin 1
 2208
 0.22
chr6_140783983_140784266 0.29 ENSG00000221336
 .
 197726
 0.03
chr8_41009602_41009753 0.29 ENSG00000263372
 .
 118985
 0.05
chr10_112158236_112158389 0.29 ENSG00000221359
 .
 35687
 0.17
chr12_120667456_120667944 0.29 PXN
 paxillin
 3053
 0.16
chr5_77881787_77882057 0.29 LHFPL2
 lipoma HMGIC fusion partner-like 2
 36948
 0.23
chr17_58218497_58218710 0.29 CA4
 carbonic anhydrase IV
 8694
 0.18
chr1_41356534_41356685 0.28 RP5-1066H13.4
27023
 0.15
chr11_7913917_7914068 0.28 ENSG00000252769
 .
 3166
 0.19
chr3_183740027_183740178 0.28 ABCC5
 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
 4299
 0.14
chr11_47560816_47560967 0.28 CELF1
 CUGBP, Elav-like family member 1
 13778
 0.08
chr6_100677123_100677274 0.28 RP1-121G13.2
197796
 0.03
chr2_171829322_171830003 0.28 GORASP2
 golgi reassembly stacking protein 2, 55kDa
 43831
 0.15
chr2_65214115_65214266 0.28 SLC1A4
 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
 1434
 0.38
chr2_110087186_110087362 0.28 ENSG00000265965
 .
 157193
 0.04
chr9_75169117_75169268 0.28 ENSG00000238402
 .
 27040
 0.21
chr2_48646919_48647208 0.28 PPP1R21
 protein phosphatase 1, regulatory subunit 21
 20845
 0.21
chr10_25348795_25348946 0.28 ENSG00000266069
 .
 31613
 0.16
chr11_44586009_44586190 0.28 CD82
 CD82 molecule
 122
 0.97
chr1_20930163_20930437 0.28 CDA
 cytidine deaminase
 14859
 0.16
chr4_38103387_38103538 0.27 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
 55970
 0.16
chr1_172446166_172446317 0.27 C1orf105
 chromosome 1 open reading frame 105
 24208
 0.17
chr10_126029743_126029894 0.27 OAT
 ornithine aminotransferase
 77687
 0.1
chr15_62910288_62910439 0.27 RP11-625H11.1
 Uncharacterized protein
 27017
 0.18
chr10_73620641_73620884 0.27 PSAP
 prosaposin
 9636
 0.2
chr16_73098361_73099003 0.27 ZFHX3
 zinc finger homeobox 3
 5085
 0.26
chr17_19215367_19215621 0.27 EPN2-AS1
 EPN2 antisense RNA 1
 5920
 0.12
chr15_101652404_101652555 0.27 RP11-505E24.2
26208
 0.2
chr8_81665342_81665642 0.26 ENSG00000212429
 .
 3564
 0.28
chr1_62146544_62146695 0.26 TM2D1
 TM2 domain containing 1
 44186
 0.15
chr20_2795102_2795253 0.26 TMEM239
 CDNA FLJ26142 fis, clone TST04526; Transmembrane protein 239; Uncharacterized protein
 437
 0.45
chr1_53977593_53977891 0.26 DMRTB1
 DMRT-like family B with proline-rich C-terminal, 1
 52670
 0.14
chr8_96111972_96112794 0.26 RP11-320N21.2
12231
 0.16
chr1_22623912_22624063 0.26 ENSG00000266564
 .
 31255
 0.21
chr12_45829168_45829319 0.26 ENSG00000239178
 .
 119199
 0.06
chr10_126805401_126805552 0.26 CTBP2
 C-terminal binding protein 2
 41809
 0.18
chr1_167127568_167127862 0.26 RP11-277B15.2
37002
 0.13
chr5_122765001_122765271 0.26 CEP120
 centrosomal protein 120kDa
 5850
 0.29
chr7_150097245_150097396 0.25 RP4-584D14.6
16347
 0.11
chr12_132347924_132348141 0.25 MMP17
 matrix metallopeptidase 17 (membrane-inserted)
 18192
 0.15
chr9_129110024_129110380 0.25 MVB12B
 multivesicular body subunit 12B
 12676
 0.24
chr7_102515337_102515656 0.25 ENSG00000238324
 .
 17599
 0.16
chr22_36720785_36721049 0.25 ENSG00000266345
 .
 8671
 0.19
chr2_26981199_26981390 0.25 SLC35F6
 solute carrier family 35, member F6
 5862
 0.19
chr6_125203361_125203883 0.25 RNF217
 ring finger protein 217
 80069
 0.11
chr16_67742664_67742903 0.25 GFOD2
 glucose-fructose oxidoreductase domain containing 2
 10541
 0.11
chr16_68986638_68986789 0.25 RP11-521L9.2
18990
 0.18
chr3_128267799_128268165 0.25 C3orf27
 chromosome 3 open reading frame 27
 26947
 0.16
chrX_45182411_45182562 0.25 RP11-342D14.1
2783
 0.41
chr1_32049799_32049950 0.25 TINAGL1
 tubulointerstitial nephritis antigen-like 1
 7735
 0.14
chr19_42900464_42900801 0.25 LIPE-AS1
 LIPE antisense RNA 1
 648
 0.56
chr7_76057799_76057950 0.25 ZP3
 zona pellucida glycoprotein 3 (sperm receptor)
 81
 0.96
chr10_116072655_116072806 0.25 VWA2
 von Willebrand factor A domain containing 2
 73641
 0.09
chr20_48310267_48310418 0.25 B4GALT5
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
 20073
 0.18
chr2_201622113_201622264 0.25 ENSG00000201737
 .
 18119
 0.14
chr17_32698121_32698371 0.24 CCL1
 chemokine (C-C motif) ligand 1
 7996
 0.18
chr4_5637335_5637511 0.24 EVC2
 Ellis van Creveld syndrome 2
 72871
 0.1
chr5_81701965_81702116 0.24 ATP6AP1L
 ATPase, H+ transporting, lysosomal accessory protein 1-like
 100874
 0.08
chr2_145082101_145082252 0.24 GTDC1
 glycosyltransferase-like domain containing 1
 4739
 0.34
chr7_127661423_127661614 0.24 LRRC4
 leucine rich repeat containing 4
 9540
 0.25
chr8_37468333_37468484 0.24 ENSG00000223215
 .
 58008
 0.1
chr14_23316976_23317711 0.24 ENSG00000212335
 .
 4594
 0.09
chr1_184591672_184591823 0.24 ENSG00000252790
 .
 55321
 0.15
chr17_66449042_66449331 0.24 WIPI1
 WD repeat domain, phosphoinositide interacting 1
 4376
 0.23
chr13_33804052_33804203 0.23 STARD13
 StAR-related lipid transfer (START) domain containing 13
 23984
 0.2
chr20_30199424_30199575 0.23 ENSG00000264395
 .
 4510
 0.13
chrX_22153582_22153733 0.23 PHEX-AS1
 PHEX antisense RNA 1
 37443
 0.16
chr14_59219843_59220151 0.23 ENSG00000221427
 .
 17967
 0.27
chr15_74274351_74275014 0.23 STOML1
 stomatin (EPB72)-like 1
 9493
 0.15
chr13_32708450_32708601 0.23 FRY
 furry homolog (Drosophila)
 73524
 0.11
chr13_49671478_49671629 0.23 ENSG00000199788
 .
 2026
 0.36
chr2_28660054_28660205 0.23 PLB1
 phospholipase B1
 19883
 0.17
chr8_26498187_26498401 0.23 DPYSL2
 dihydropyrimidinase-like 2
 62373
 0.14
chr5_125808253_125808404 0.23 RP11-517I3.1
5005
 0.23
chr2_33352313_33352464 0.23 LTBP1
 latent transforming growth factor beta binding protein 1
 7085
 0.3
chr19_39853657_39853808 0.22 ENSG00000241983
 .
 6061
 0.09
chr22_35907056_35907207 0.22 RASD2
 RASD family, member 2
 29784
 0.19
chr18_21795564_21795715 0.22 ENSG00000206766
 .
 2625
 0.23
chr6_167142675_167142845 0.22 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
 28639
 0.23
chr4_139531486_139531637 0.22 ENSG00000238971
 .
 201359
 0.03
chr5_139721285_139721505 0.22 HBEGF
 heparin-binding EGF-like growth factor
 4793
 0.14
chr3_69439182_69439463 0.22 FRMD4B
 FERM domain containing 4B
 3892
 0.36
chr1_223308438_223308608 0.22 TLR5
 toll-like receptor 5
 425
 0.91
chr1_230850007_230850201 0.22 AGT
 angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
 61
 0.97
chr15_91285398_91285560 0.22 ENSG00000200677
 .
 13063
 0.14
chr5_139621230_139621381 0.22 CTB-131B5.2
41557
 0.1
chr14_72180385_72180536 0.22 SIPA1L1
 signal-induced proliferation-associated 1 like 1
 94987
 0.09
chr8_37376201_37376352 0.22 RP11-150O12.6
1737
 0.48
chr3_151893804_151894059 0.22 MBNL1
 muscleblind-like splicing regulator 1
 91898
 0.08
chr7_134893432_134893608 0.22 WDR91
 WD repeat domain 91
 2131
 0.24
chr1_144085227_144085501 0.22 NBPF8
 neuroblastoma breakpoint family, member 8
 61444
 0.14
chr6_140784427_140784578 0.22 ENSG00000221336
 .
 197348
 0.03
chr2_85933045_85933196 0.22 GNLY
 granulysin
 10629
 0.13
chr22_46498265_46498416 0.22 ENSG00000198986
 .
 10289
 0.1
chr3_15672619_15672770 0.22 BTD
 biotinidase
 29218
 0.14
chr1_1295387_1295783 0.22 MXRA8
 matrix-remodelling associated 8
 1572
 0.16
chr15_35330956_35331107 0.22 ZNF770
 zinc finger protein 770
 50543
 0.14
chr22_46485560_46485711 0.22 ENSG00000266533
 .
 1289
 0.27
chr14_63904786_63905352 0.22 ENSG00000264995
 .
 24655
 0.16
chr1_42641010_42641161 0.22 GUCA2A
 guanylate cyclase activator 2A (guanylin)
 10696
 0.19
chr13_80657315_80657466 0.22 SPRY2
 sprouty homolog 2 (Drosophila)
 256404
 0.02
chr5_142280838_142280989 0.22 ARHGAP26
 Rho GTPase activating protein 26
 5974
 0.27
chr2_241860537_241860698 0.21 AC104809.3
 Protein LOC728763
 1369
 0.36
chr10_95136688_95136839 0.21 MYOF
 myoferlin
 105188
 0.06
chr8_85095605_85095756 0.21 RALYL
 RALY RNA binding protein-like
 89
 0.99
chr22_46487788_46487939 0.21 ENSG00000266533
 .
 939
 0.38
chr2_19015414_19015565 0.21 NT5C1B
 5'-nucleotidase, cytosolic IB
 244651
 0.02
chr10_128777765_128777916 0.21 RP11-223P11.3
46846
 0.16
chr17_36433052_36433525 0.21 RP11-1407O15.2
 TBC1 domain family member 3
 11447
 0.15
chr3_138187920_138188071 0.21 CEP70
 centrosomal protein 70kDa
 31027
 0.18
chr1_215843470_215843621 0.21 ENSG00000202498
 .
 40086
 0.2
chr11_45067696_45067847 0.21 PRDM11
 PR domain containing 11
 47793
 0.17
chr9_133323468_133323619 0.21 ENSG00000238298
 .
 1698
 0.3
chr12_57611386_57611537 0.21 NXPH4
 neurexophilin 4
 883
 0.39
chrX_69394860_69395105 0.21 DGAT2L6
 diacylglycerol O-acyltransferase 2-like 6
 2351
 0.2
chr9_139492984_139493135 0.21 ENSG00000252440
 .
 3908
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP2E

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.2 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 0.2 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.1 0.2 GO:0052305 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1 0.2 GO:0071436 sodium ion export(GO:0071436)
0.1 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.1 GO:0046471 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.0 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.0 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.0 GO:0090103 cochlea morphogenesis(GO:0090103)
0.0 0.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0032353 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.1 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.1 GO:0032226 positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0 0.1 GO:0006991 response to sterol depletion(GO:0006991)
0.0 0.1 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.0 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:0015853 adenine transport(GO:0015853)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.0 0.0 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.0 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.0 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.0 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.0 GO:0048539 bone marrow development(GO:0048539)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0033646 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.0 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.0 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 1.0 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0032190 acrosin binding(GO:0032190)
0.1 0.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.0 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway