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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.83

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Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41

Gene Symbol Gene ID Gene Info
TFEC
ENSG00000105967.11 transcription factor EC
MITF
ENSG00000187098.10 melanocyte inducing transcription factor
ARNTL
ENSG00000133794.13 aryl hydrocarbon receptor nuclear translocator like
BHLHE41
ENSG00000123095.5 basic helix-loop-helix family member e41

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_13230039_13230195ARNTL680820.1279700.863.1e-03Click!
chr11_13312870_13313021ARNTL135130.259982-0.835.8e-03Click!
chr11_13229796_13230015ARNTL682940.1275280.781.3e-02Click!
chr11_13282555_13282706ARNTL155690.2692930.752.1e-02Click!
chr11_13314702_13314853ARNTL153450.254012-0.732.5e-02Click!
chr12_26277295_26278057BHLHE413840.777876-0.665.3e-02Click!
chr12_26278311_26278658BHLHE414240.5399530.039.3e-01Click!
chr3_69789658_69789810MITF11120.6070080.801.0e-02Click!
chr3_69813958_69814283MITF11580.5580410.732.6e-02Click!
chr3_69813399_69813761MITF6180.7826250.703.4e-02Click!
chr3_69810828_69810979MITF9720.6339220.694.0e-02Click!
chr3_69788296_69788550MITF1630.969196-0.646.5e-02Click!
chr7_115556505_115556656TFEC517240.167210-0.637.2e-02Click!
chr7_115662328_115662479TFEC83920.309240-0.618.1e-02Click!
chr7_115803556_115803707TFEC36810.2982890.608.5e-02Click!
chr7_115808920_115809071TFEC90450.2413130.608.9e-02Click!
chr7_115785682_115785833TFEC141930.2494700.581.0e-01Click!

Activity of the TFEC_MITF_ARNTL_BHLHE41 motif across conditions

Conditions sorted by the z-value of the TFEC_MITF_ARNTL_BHLHE41 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_114280008_114280159 0.83 ATP4B
 ATPase, H+/K+ exchanging, beta polypeptide
 32418
 0.15
chr13_114280229_114280380 0.59 ATP4B
 ATPase, H+/K+ exchanging, beta polypeptide
 32197
 0.15
chr16_85549609_85549893 0.45 ENSG00000264203
 .
 74653
 0.09
chr13_44730147_44730391 0.43 SMIM2-IT1
 SMIM2 intronic transcript 1 (non-protein coding)
 2089
 0.32
chr6_16681395_16681795 0.41 RP1-151F17.1
79774
 0.1
chr3_125322024_125322175 0.41 OSBPL11
 oxysterol binding protein-like 11
 8165
 0.22
chr5_343224_343631 0.41 AHRR
 aryl-hydrocarbon receptor repressor
 216
 0.94
chr10_81160624_81160775 0.38 RP11-342M3.5
18615
 0.19
chr2_235866357_235866729 0.36 SH3BP4
 SH3-domain binding protein 4
 5823
 0.35
chr2_40266109_40266315 0.34 SLC8A1-AS1
 SLC8A1 antisense RNA 1
 3278
 0.4
chr5_14261499_14261650 0.34 TRIO
 trio Rho guanine nucleotide exchange factor
 29512
 0.26
chr1_210431394_210431545 0.34 SERTAD4-AS1
 SERTAD4 antisense RNA 1
 24077
 0.19
chr5_14174403_14174686 0.33 TRIO
 trio Rho guanine nucleotide exchange factor
 9363
 0.32
chr6_52376693_52376847 0.33 TRAM2
 translocation associated membrane protein 2
 64943
 0.11
chr18_52454307_52454540 0.32 RAB27B
 RAB27B, member RAS oncogene family
 41007
 0.2
chr1_27855366_27855678 0.32 RP1-159A19.4
3206
 0.23
chr14_36538512_36538663 0.31 ENSG00000212071
 .
 127187
 0.05
chr13_40105934_40106139 0.31 LHFP
 lipoma HMGIC fusion partner
 71272
 0.11
chr11_10696838_10697077 0.30 MRVI1
 murine retrovirus integration site 1 homolog
 18104
 0.17
chr17_40128851_40129002 0.29 DNAJC7
 DnaJ (Hsp40) homolog, subfamily C, member 7
 5413
 0.13
chr9_82104147_82104538 0.29 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 82346
 0.12
chr21_43953040_43953239 0.29 SLC37A1
 solute carrier family 37 (glucose-6-phosphate transporter), member 1
 18505
 0.13
chr16_80755255_80755539 0.29 CTD-2055G21.1
14860
 0.21
chr2_9375733_9375964 0.29 ASAP2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 28954
 0.23
chr17_74526963_74527181 0.29 CYGB
 cytoglobin
 1075
 0.29
chr17_3545041_3545192 0.29 CTNS
 cystinosin, lysosomal cystine transporter
 1675
 0.21
chr2_47313454_47313781 0.28 AC073283.7
18656
 0.18
chr9_93880537_93881196 0.28 AUH
 AU RNA binding protein/enoyl-CoA hydratase
 243311
 0.02
chr17_9160012_9160446 0.28 RP11-85B7.4
26262
 0.21
chr11_69263417_69264003 0.28 CCND1
 cyclin D1
 192145
 0.03
chr10_129706485_129706650 0.28 PTPRE
 protein tyrosine phosphatase, receptor type, E
 1151
 0.53
chr7_104614373_104614618 0.28 ENSG00000251911
 .
 2761
 0.25
chr6_89744917_89745362 0.27 ENSG00000223001
 .
 28270
 0.13
chr15_35598915_35599148 0.27 ENSG00000265102
 .
 65534
 0.14
chr9_137537253_137537404 0.27 COL5A1
 collagen, type V, alpha 1
 3708
 0.25
chr6_111886228_111886379 0.27 TRAF3IP2-AS1
 TRAF3IP2 antisense RNA 1
 151
 0.95
chr14_105216209_105216503 0.27 SIVA1
 SIVA1, apoptosis-inducing factor
 3081
 0.16
chr1_9952782_9953028 0.26 CTNNBIP1
 catenin, beta interacting protein 1
 390
 0.81
chr2_33516894_33517045 0.26 LTBP1
 latent transforming growth factor beta binding protein 1
 254
 0.93
chr1_41235374_41235525 0.26 ENSG00000207962
 .
 12493
 0.12
chr6_3139599_3139904 0.26 BPHL
 biphenyl hydrolase-like (serine hydrolase)
 908
 0.5
chr5_14445022_14445319 0.26 TRIO
 trio Rho guanine nucleotide exchange factor
 43387
 0.2
chrX_153770737_153771284 0.26 IKBKG
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
 532
 0.58
chr1_59602387_59602647 0.26 FGGY
 FGGY carbohydrate kinase domain containing
 159793
 0.04
chr3_185375823_185376288 0.25 SENP2
 SUMO1/sentrin/SMT3 specific peptidase 2
 44912
 0.15
chr7_73497247_73497589 0.25 LIMK1
 LIM domain kinase 1
 155
 0.96
chr1_61637743_61637894 0.25 RP4-802A10.1
47413
 0.17
chr17_26312086_26312243 0.25 ENSG00000251818
 .
 33632
 0.13
chr12_48147567_48147718 0.25 SLC48A1
 solute carrier family 48 (heme transporter), member 1
 57
 0.96
chr4_41062724_41062875 0.24 ENSG00000199790
 .
 23825
 0.18
chr12_15112233_15112384 0.24 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
 1892
 0.3
chr1_95328697_95328848 0.24 SLC44A3
 solute carrier family 44, member 3
 4115
 0.22
chr8_97594056_97594225 0.24 SDC2
 syndecan 2
 1563
 0.51
chr10_26845646_26845984 0.24 ENSG00000199733
 .
 47297
 0.17
chr2_64343006_64343324 0.24 AC074289.1
27208
 0.19
chr2_11343535_11343897 0.24 ENSG00000207267
 .
 30398
 0.15
chr16_29280883_29281034 0.24 RP11-231C14.6
42713
 0.13
chr2_232229722_232230070 0.24 ENSG00000263641
 .
 2477
 0.26
chr8_18953240_18953562 0.23 PSD3
 pleckstrin and Sec7 domain containing 3
 11161
 0.29
chr8_139855770_139855921 0.23 COL22A1
 collagen, type XXII, alpha 1
 64040
 0.16
chr16_73104328_73104761 0.23 ZFHX3
 zinc finger homeobox 3
 10947
 0.24
chr17_30822967_30823118 0.23 RP11-466A19.1
488
 0.69
chr17_62038673_62039025 0.23 SCN4A
 sodium channel, voltage-gated, type IV, alpha subunit
 11429
 0.12
chr1_32049799_32049950 0.23 TINAGL1
 tubulointerstitial nephritis antigen-like 1
 7735
 0.14
chr10_114021204_114021502 0.23 TECTB
 tectorin beta
 22140
 0.23
chr3_31212208_31212359 0.23 ENSG00000265376
 .
 9004
 0.28
chr12_52569964_52570127 0.23 KRT80
 keratin 80
 15739
 0.12
chr12_78450993_78451144 0.22 RP11-136F16.1
34449
 0.22
chr1_8740143_8740294 0.22 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 23060
 0.23
chr8_105378884_105379035 0.22 DCSTAMP
 dendrocyte expressed seven transmembrane protein
 18190
 0.18
chr22_38573907_38574208 0.22 PLA2G6
 phospholipase A2, group VI (cytosolic, calcium-independent)
 2354
 0.22
chr17_983655_983915 0.22 ABR
 active BCR-related
 1399
 0.45
chr9_127116150_127116301 0.22 ENSG00000264237
 .
 3415
 0.26
chr14_59721391_59721542 0.22 DAAM1
 dishevelled associated activator of morphogenesis 1
 8707
 0.3
chr10_50887461_50887643 0.22 C10orf53
 chromosome 10 open reading frame 53
 145
 0.97
chr19_6463883_6464309 0.22 CRB3
 crumbs homolog 3 (Drosophila)
 194
 0.84
chr3_168823031_168823291 0.21 MECOM
 MDS1 and EVI1 complex locus
 22661
 0.28
chr17_40998909_40999245 0.21 AOC2
 amine oxidase, copper containing 2 (retina-specific)
 2459
 0.12
chr6_43091623_43091783 0.21 PTK7
 protein tyrosine kinase 7
 6626
 0.13
chr2_174937001_174937255 0.21 SP3
 Sp3 transcription factor
 106698
 0.07
chr11_19702330_19702481 0.21 NAV2
 neuron navigator 2
 32476
 0.19
chr1_183250951_183251102 0.21 NMNAT2
 nicotinamide nucleotide adenylyltransferase 2
 22983
 0.23
chr2_238066163_238066314 0.21 COPS8
 COP9 signalosome subunit 8
 71652
 0.1
chr6_15897284_15897435 0.21 MYLIP
 myosin regulatory light chain interacting protein
 231997
 0.02
chr21_43460258_43460538 0.21 UMODL1
 uromodulin-like 1
 22670
 0.16
chr14_33698651_33698802 0.21 NPAS3
 neuronal PAS domain protein 3
 14208
 0.32
chr13_33000508_33000853 0.21 N4BP2L1
 NEDD4 binding protein 2-like 1
 1471
 0.43
chr13_111033798_111033949 0.20 ENSG00000238629
 .
 32679
 0.18
chr1_53601169_53601320 0.20 SLC1A7
 solute carrier family 1 (glutamate transporter), member 7
 7005
 0.14
chr2_102079958_102080109 0.20 RFX8
 RFX family member 8, lacking RFX DNA binding domain
 10704
 0.26
chr8_26485560_26485711 0.20 DPYSL2
 dihydropyrimidinase-like 2
 49714
 0.17
chr19_47239966_47240117 0.20 ENSG00000222614
 .
 472
 0.64
chr3_127454470_127454692 0.20 MGLL
 monoglyceride lipase
 619
 0.78
chr3_72378625_72378776 0.20 ENSG00000212070
 .
 67121
 0.13
chr4_56042024_56042324 0.20 ENSG00000239545
 .
 39905
 0.15
chr19_2188884_2189035 0.20 DOT1L
 DOT1-like histone H3K79 methyltransferase
 24630
 0.08
chrX_48350514_48350665 0.20 FTSJ1
 FtsJ RNA methyltransferase homolog 1 (E. coli)
 14209
 0.1
chr16_85597214_85597712 0.20 GSE1
 Gse1 coiled-coil protein
 47552
 0.14
chr2_120980604_120980755 0.20 TMEM185B
 transmembrane protein 185B
 305
 0.89
chr12_1579383_1579534 0.20 WNT5B
 wingless-type MMTV integration site family, member 5B
 59599
 0.11
chr12_112043846_112043997 0.20 ATXN2
 ataxin 2
 6441
 0.18
chr21_39850220_39850518 0.20 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
 19976
 0.28
chr11_62369886_62370188 0.20 MTA2
 metastasis associated 1 family, member 2
 725
 0.33
chr2_101507765_101507916 0.20 NPAS2
 neuronal PAS domain protein 2
 33768
 0.17
chr17_773553_773704 0.20 NXN
 nucleoredoxin
 6277
 0.16
chr6_157469967_157470240 0.19 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 58
 0.98
chr22_41050157_41050308 0.19 MKL1
 megakaryoblastic leukemia (translocation) 1
 17537
 0.19
chr1_44705174_44705804 0.19 ERI3-IT1
 ERI3 intronic transcript 1 (non-protein coding)
 4456
 0.21
chr2_40663401_40663552 0.19 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
 6032
 0.34
chr7_41187429_41187580 0.19 AC005160.3
372347
 0.01
chr9_136325577_136325728 0.19 CACFD1
 calcium channel flower domain containing 1
 497
 0.68
chr3_127484247_127484497 0.19 MGLL
 monoglyceride lipase
 18479
 0.22
chr17_39240048_39240199 0.19 KRTAP4-7
 keratin associated protein 4-7
 336
 0.68
chr12_69007841_69008681 0.19 RAP1B
 RAP1B, member of RAS oncogene family
 3456
 0.26
chr21_33846975_33847126 0.19 EVA1C
 eva-1 homolog C (C. elegans)
 46408
 0.11
chr15_68645681_68645891 0.19 FEM1B
 fem-1 homolog b (C. elegans)
 63236
 0.11
chr6_43958464_43958740 0.19 C6orf223
 chromosome 6 open reading frame 223
 9715
 0.17
chr16_85590754_85591408 0.19 GSE1
 Gse1 coiled-coil protein
 53934
 0.13
chr11_107799088_107799595 0.19 RAB39A
 RAB39A, member RAS oncogene family
 112
 0.77
chr15_73979466_73979617 0.19 CD276
 CD276 molecule
 2194
 0.36
chr6_26432216_26432367 0.19 BTN3A3
 butyrophilin, subfamily 3, member A3
 8409
 0.11
chr2_121528712_121528929 0.19 GLI2
 GLI family zinc finger 2
 21165
 0.27
chr7_5674087_5674709 0.19 FSCN1
 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
 40081
 0.12
chr13_111866660_111867080 0.19 ARHGEF7
 Rho guanine nucleotide exchange factor (GEF) 7
 9234
 0.25
chr17_40554278_40554429 0.19 ENSG00000221020
 .
 3326
 0.15
chr9_36158585_36158800 0.18 CCIN
 calicin
 10697
 0.17
chr13_30567918_30568069 0.18 LINC00572
 long intergenic non-protein coding RNA 572
 67205
 0.13
chr7_101524016_101524398 0.18 CTA-339C12.1
56198
 0.12
chr19_52270463_52270746 0.18 FPR2
 formyl peptide receptor 2
 1027
 0.41
chr8_145692200_145692386 0.18 KIFC2
 kinesin family member C2
 645
 0.36
chr2_121673188_121673339 0.18 GLI2
 GLI family zinc finger 2
 118342
 0.06
chr9_81760534_81760685 0.18 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 426079
 0.01
chr15_63322256_63322433 0.18 TPM1
 tropomyosin 1 (alpha)
 12487
 0.18
chr17_7837465_7837616 0.18 CNTROB
 centrobin, centrosomal BRCA2 interacting protein
 1142
 0.27
chr10_80997764_80997915 0.18 ZMIZ1
 zinc finger, MIZ-type containing 1
 68136
 0.12
chr10_105251971_105252122 0.18 NEURL1
 neuralized E3 ubiquitin protein ligase 1
 1690
 0.23
chr14_104018069_104018220 0.18 ENSG00000252469
 .
 1462
 0.17
chr21_46852549_46852700 0.18 COL18A1-AS1
 COL18A1 antisense RNA 1
 7639
 0.17
chr3_8499776_8500071 0.18 LMCD1-AS1
 LMCD1 antisense RNA 1 (head to head)
 43361
 0.15
chr10_81000941_81001092 0.18 ZMIZ1
 zinc finger, MIZ-type containing 1
 64959
 0.13
chr2_30454852_30455048 0.18 LBH
 limb bud and heart development
 69
 0.98
chr21_42484961_42485351 0.18 LINC00323
 long intergenic non-protein coding RNA 323
 34194
 0.15
chr1_108661134_108661345 0.18 SLC25A24
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
 74201
 0.09
chr11_61809719_61809884 0.18 AP003733.1
 Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
 74348
 0.07
chr20_2795832_2795989 0.18 C20orf141
 chromosome 20 open reading frame 141
 253
 0.52
chr12_124870235_124870636 0.18 NCOR2
 nuclear receptor corepressor 2
 2935
 0.37
chr13_25485405_25485556 0.18 CENPJ
 centromere protein J
 7348
 0.24
chr19_4391069_4391613 0.18 SH3GL1
 SH3-domain GRB2-like 1
 734
 0.43
chr1_87244168_87244361 0.18 SH3GLB1
 SH3-domain GRB2-like endophilin B1
 73686
 0.09
chr8_85095605_85095756 0.18 RALYL
 RALY RNA binding protein-like
 89
 0.99
chr17_81021007_81021158 0.18 B3GNTL1
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
 11396
 0.21
chr2_113470510_113470661 0.18 NT5DC4
 5'-nucleotidase domain containing 4
 8478
 0.2
chr2_207974591_207974747 0.18 ENSG00000253008
 .
 128
 0.96
chr22_38597727_38597878 0.18 MAFF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
 87
 0.95
chr6_37961556_37961707 0.18 ZFAND3
 zinc finger, AN1-type domain 3
 63896
 0.12
chr3_13549513_13549664 0.17 FBLN2
 fibulin 2
 24236
 0.16
chr7_92369983_92370216 0.17 ENSG00000206763
 .
 38971
 0.18
chr13_101999259_101999410 0.17 NALCN
 sodium leak channel, non-selective
 52171
 0.18
chr3_148184411_148184664 0.17 AGTR1
 angiotensin II receptor, type 1
 231034
 0.02
chr9_86784994_86785145 0.17 RP11-380F14.2
108065
 0.06
chr1_23710189_23710340 0.17 TCEA3
 transcription elongation factor A (SII), 3
 3648
 0.16
chr3_149865017_149865176 0.17 RP11-167H9.4
49277
 0.15
chr3_8890314_8890465 0.17 RAD18
 RAD18 homolog (S. cerevisiae)
 53693
 0.11
chr16_79204965_79205116 0.17 RP11-556H2.2
65186
 0.11
chrY_2709779_2709930 0.17 RPS4Y1
 ribosomal protein S4, Y-linked 1
 107
 0.98
chr17_39261210_39261361 0.17 KRTAP4-9
 keratin associated protein 4-9
 299
 0.71
chr10_135073858_135074032 0.17 MIR202HG
 MIR202 host gene (non-protein coding)
 12550
 0.1
chr14_62004306_62004579 0.17 RP11-47I22.1
7563
 0.2
chr18_494818_494969 0.17 COLEC12
 collectin sub-family member 12
 5829
 0.22
chr12_19699587_19699738 0.17 AEBP2
 AE binding protein 2
 46599
 0.18
chr8_41656318_41656469 0.17 ANK1
 ankyrin 1, erythrocytic
 1253
 0.45
chr2_46343393_46343544 0.17 AC017006.2
37501
 0.18
chr3_46543509_46543660 0.17 RTP3
 receptor (chemosensory) transporter protein 3
 4603
 0.17
chr1_20820718_20821010 0.17 CAMK2N1
 calcium/calmodulin-dependent protein kinase II inhibitor 1
 8151
 0.19
chr1_94127454_94127736 0.17 BCAR3
 breast cancer anti-estrogen resistance 3
 19331
 0.22
chr3_66083676_66083827 0.17 SLC25A26
 solute carrier family 25 (S-adenosylmethionine carrier), member 26
 35534
 0.18
chr3_126398342_126398493 0.17 TXNRD3
 thioredoxin reductase 3
 24419
 0.17
chr1_153508734_153509122 0.17 S100A6
 S100 calcium binding protein A6
 208
 0.85
chr12_92378267_92378418 0.17 C12orf79
 chromosome 12 open reading frame 79
 152455
 0.04
chr11_116966114_116966583 0.17 SIK3
 SIK family kinase 3
 2639
 0.22
chr9_127051927_127052078 0.17 NEK6
 NIMA-related kinase 6
 2248
 0.29
chr5_145564514_145564665 0.16 LARS
 leucyl-tRNA synthetase
 2366
 0.3
chr1_113265986_113266348 0.16 FAM19A3
 family with sequence similarity 19 (chemokine (C-C motif)-like), member A3
 2968
 0.15
chr20_62530297_62530448 0.16 DNAJC5
 DnaJ (Hsp40) homolog, subfamily C, member 5
 3837
 0.09
chr12_71439781_71440156 0.16 CTD-2021H9.2
58338
 0.13
chr4_164253447_164254003 0.16 NPY1R
 neuropeptide Y receptor Y1
 23
 0.98
chr2_201652506_201652946 0.16 ENSG00000201737
 .
 12419
 0.12
chr22_41418613_41418788 0.16 ENSG00000222698
 .
 22801
 0.13
chr5_41793545_41793696 0.16 OXCT1
 3-oxoacid CoA transferase 1
 862
 0.71
chr16_4428001_4428209 0.16 VASN
 vasorin
 6256
 0.13
chr3_25823149_25824090 0.16 NGLY1
 N-glycanase 1
 744
 0.48
chr6_109745594_109745745 0.16 ENSG00000239160
 .
 9774
 0.12
chr16_57095437_57095664 0.16 RP11-322D14.2
3141
 0.17
chr18_32288595_32288746 0.16 DTNA
 dystrobrevin, alpha
 1578
 0.51
chr3_111686013_111686245 0.16 ABHD10
 abhydrolase domain containing 10
 11728
 0.19
chr20_43332745_43332896 0.16 RP11-445H22.3
8083
 0.13
chr5_54179191_54179535 0.16 ENSG00000221073
 .
 30587
 0.19
chr19_15377356_15377507 0.16 BRD4
 bromodomain containing 4
 13831
 0.16
chr17_48718114_48718630 0.16 ABCC3
 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
 6154
 0.13
chr1_198849285_198849436 0.16 ENSG00000207759
 .
 21078
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.1 0.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.1 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.4 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0021508 floor plate formation(GO:0021508)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.2 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.1 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.0 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.2 GO:0061245 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 0.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.1 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.2 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.0 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.0 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.0 GO:1900121 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0014821 phasic smooth muscle contraction(GO:0014821)
0.0 0.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.1 GO:0001975 response to amphetamine(GO:0001975)
0.0 0.0 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0 0.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0048596 embryonic camera-type eye morphogenesis(GO:0048596)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.0 GO:0045079 negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.1 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.0 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.0 GO:0019240 citrulline biosynthetic process(GO:0019240)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.0 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.1 0.2 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.4 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.0 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.0 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.0 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.0 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0004312 fatty acid synthase activity(GO:0004312)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors