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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for TGIF1

Z-value: 0.92

Motif logo

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Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
TGIF1
ENSG00000177426.16 TGFB induced factor homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr18_3340712_3340863TGIF1708190.0809680.627.6e-02Click!
chr18_3459581_3459732TGIF142440.247691-0.581.0e-01Click!
chr18_3446975_3447243TGIF14980.8192880.541.3e-01Click!
chr18_3478848_3478999TGIF1235110.181872-0.531.4e-01Click!
chr18_3448954_3449105TGIF13820.8774120.521.5e-01Click!

Activity of the TGIF1 motif across conditions

Conditions sorted by the z-value of the TGIF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_33208774_33208970 0.21 ITGB1
 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 11441
 0.29
chr22_36000465_36000757 0.21 MB
 myoglobin
 11149
 0.19
chr1_156196195_156196346 0.20 PMF1-BGLAP
 PMF1-BGLAP readthrough
 13470
 0.09
chr5_167532981_167533278 0.20 ENSG00000253065
 .
 72919
 0.1
chr21_34461417_34461568 0.19 AP000282.2
18082
 0.16
chr7_4166622_4166773 0.18 SDK1
 sidekick cell adhesion molecule 1
 176145
 0.03
chr1_156509588_156509739 0.18 ENSG00000238843
 .
 10541
 0.11
chr10_34004252_34004403 0.17 NRP1
 neuropilin 1
 379137
 0.01
chr4_48900915_48901066 0.17 OCIAD2
 OCIA domain containing 2
 7784
 0.2
chr21_41842867_41843018 0.17 ENSG00000207147
 .
 42129
 0.18
chr7_10018425_10018576 0.17 ENSG00000212422
 .
 243924
 0.02
chr9_90146510_90146661 0.17 DAPK1-IT1
 DAPK1 intronic transcript 1 (non-protein coding)
 21784
 0.22
chr8_19243061_19243460 0.16 SH2D4A
 SH2 domain containing 4A
 66159
 0.14
chr11_12194861_12195012 0.16 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 11233
 0.26
chr1_185135340_185135491 0.16 SWT1
 SWT1 RNA endoribonuclease homolog (S. cerevisiae)
 8801
 0.19
chr13_92002817_92003060 0.16 ENSG00000215417
 .
 59
 0.99
chr16_49534864_49535143 0.16 C16orf78
 chromosome 16 open reading frame 78
 127269
 0.05
chr2_45735351_45735502 0.16 SRBD1
 S1 RNA binding domain 1
 59728
 0.13
chr20_57601860_57602011 0.16 ATP5E
 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
 5412
 0.15
chr8_93693450_93693601 0.15 ENSG00000221172
 .
 45962
 0.18
chr2_207380556_207380707 0.15 ADAM23
 ADAM metallopeptidase domain 23
 72040
 0.1
chr5_56784424_56784602 0.15 ACTBL2
 actin, beta-like 2
 5877
 0.24
chr10_50390146_50390361 0.15 C10orf128
 chromosome 10 open reading frame 128
 6104
 0.2
chr16_68381624_68381775 0.15 ENSG00000222177
 .
 18267
 0.09
chr4_6013606_6013757 0.15 C4orf50
 chromosome 4 open reading frame 50
 22136
 0.24
chr3_168334920_168335071 0.15 ENSG00000207717
 .
 65353
 0.15
chr15_41925877_41926028 0.15 MGA
 MGA, MAX dimerization protein
 12218
 0.18
chr8_121016842_121017083 0.15 COL14A1
 collagen, type XIV, alpha 1
 100854
 0.07
chr7_40796116_40796267 0.15 AC005160.3
18966
 0.3
chr15_68634684_68634835 0.15 FEM1B
 fem-1 homolog b (C. elegans)
 52209
 0.13
chr9_113403073_113403248 0.15 MUSK
 muscle, skeletal, receptor tyrosine kinase
 27891
 0.21
chr11_44938433_44938696 0.15 TSPAN18
 tetraspanin 18
 10606
 0.25
chr3_16513920_16514071 0.14 RFTN1
 raftlin, lipid raft linker 1
 10377
 0.26
chr6_20564770_20564937 0.14 CDKAL1
 CDK5 regulatory subunit associated protein 1-like 1
 18281
 0.22
chr11_20029031_20029182 0.14 NAV2
 neuron navigator 2
 14996
 0.2
chr1_83171006_83171157 0.14 LPHN2
 latrophilin 2
 725508
 0.0
chr11_62321469_62322295 0.14 AHNAK
 AHNAK nucleoprotein
 1825
 0.17
chr6_109162296_109162639 0.14 ARMC2
 armadillo repeat containing 2
 7152
 0.28
chr1_145759757_145760123 0.14 PDZK1
 PDZ domain containing 1
 16677
 0.17
chr20_39561263_39561414 0.14 ENSG00000238908
 .
 78469
 0.1
chr13_21212008_21212159 0.14 ENSG00000222726
 .
 25783
 0.18
chr8_116661022_116661259 0.14 TRPS1
 trichorhinophalangeal syndrome I
 12765
 0.31
chr3_121590668_121590819 0.14 SLC15A2
 solute carrier family 15 (oligopeptide transporter), member 2
 22193
 0.15
chr6_161454710_161454940 0.14 MAP3K4
 mitogen-activated protein kinase kinase kinase 4
 11599
 0.25
chr6_82193288_82193439 0.14 RP1-300G12.2
51267
 0.16
chr11_95452659_95452810 0.14 FAM76B
 family with sequence similarity 76, member B
 67235
 0.12
chr1_157717360_157717511 0.14 FCRL2
 Fc receptor-like 2
 20129
 0.18
chr12_124230277_124230428 0.14 ATP6V0A2
 ATPase, H+ transporting, lysosomal V0 subunit a2
 4191
 0.2
chr9_12697396_12697547 0.14 TYRP1
 tyrosinase-related protein 1
 1751
 0.46
chr7_150360680_150361171 0.14 GIMAP2
 GTPase, IMAP family member 2
 21863
 0.15
chr13_103935436_103935587 0.14 SLC10A2
 solute carrier family 10 (sodium/bile acid cotransporter), member 2
 216315
 0.02
chr21_34426463_34426615 0.14 OLIG1
 oligodendrocyte transcription factor 1
 15911
 0.16
chr1_245084915_245085066 0.14 ENSG00000201758
 .
 22222
 0.14
chr15_82235742_82235893 0.14 ENSG00000222521
 .
 100818
 0.07
chr1_239701671_239701822 0.14 CHRM3
 cholinergic receptor, muscarinic 3
 90627
 0.1
chr21_26946893_26947044 0.14 ENSG00000234883
 .
 676
 0.69
chr4_159703546_159703697 0.14 ENSG00000206703
 .
 12227
 0.18
chr16_79449443_79449594 0.14 ENSG00000222244
 .
 151167
 0.04
chr14_70615527_70615823 0.14 SLC8A3
 solute carrier family 8 (sodium/calcium exchanger), member 3
 19526
 0.23
chr1_242012350_242012723 0.14 EXO1
 exonuclease 1
 283
 0.94
chr1_66556636_66556787 0.14 ENSG00000223152
 .
 3518
 0.3
chr1_168803043_168803442 0.14 ENSG00000221578
 .
 86122
 0.09
chr8_68632907_68633058 0.14 ENSG00000221660
 .
 9115
 0.21
chr2_176417653_176417879 0.14 ENSG00000221347
 .
 222665
 0.02
chr3_194838476_194838628 0.14 XXYLT1
 xyloside xylosyltransferase 1
 4369
 0.17
chr18_8455726_8455877 0.14 ENSG00000242985
 .
 16028
 0.18
chr17_27419224_27419375 0.14 TIAF1
 TGFB1-induced anti-apoptotic factor 1
 762
 0.58
chr19_16228666_16229162 0.13 RAB8A
 RAB8A, member RAS oncogene family
 6207
 0.14
chr9_80517904_80518204 0.13 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 80139
 0.11
chr6_6656190_6656366 0.13 LY86-AS1
 LY86 antisense RNA 1
 33274
 0.22
chr12_9921460_9921827 0.13 CD69
 CD69 molecule
 8146
 0.16
chr12_49213958_49214109 0.13 CACNB3
 calcium channel, voltage-dependent, beta 3 subunit
 1341
 0.26
chr4_116213074_116213225 0.13 NDST4
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
 178117
 0.03
chr2_165752418_165752569 0.13 ENSG00000223318
 .
 206
 0.94
chr16_23908795_23909009 0.13 PRKCB
 protein kinase C, beta
 60358
 0.13
chr6_13002773_13002924 0.13 PHACTR1
 phosphatase and actin regulator 1
 44634
 0.2
chr2_130569309_130569460 0.13 AC079776.2
113914
 0.06
chr12_68285414_68285565 0.13 IFNG-AS1
 IFNG antisense RNA 1
 97736
 0.09
chr15_38988151_38988528 0.13 C15orf53
 chromosome 15 open reading frame 53
 460
 0.89
chr18_53903146_53903297 0.13 ENSG00000201816
 .
 156396
 0.04
chr10_112478002_112478221 0.13 ENSG00000252036
 .
 38103
 0.13
chr17_49043165_49043316 0.13 SPAG9
 sperm associated antigen 9
 28058
 0.17
chr6_109660786_109660937 0.13 ENSG00000201023
 .
 34164
 0.12
chr6_45789023_45789174 0.13 ENSG00000252738
 .
 175257
 0.03
chr14_72595830_72595981 0.13 ENSG00000200298
 .
 106672
 0.07
chr7_101539600_101539793 0.13 CTB-181H17.1
63700
 0.11
chr11_42274588_42274739 0.13 LRRC4C
 leucine rich repeat containing 4C
 793340
 0.0
chr17_78845626_78846398 0.13 RPTOR
 regulatory associated protein of MTOR, complex 1
 50512
 0.1
chr14_49949021_49949172 0.13 ENSG00000252424
 .
 70255
 0.08
chr6_44796997_44797148 0.13 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
 126175
 0.06
chr17_1870594_1870879 0.13 CTD-2545H1.2
28172
 0.1
chr10_8374212_8374363 0.13 GATA3
 GATA binding protein 3
 277518
 0.01
chr3_138607537_138607828 0.13 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 53902
 0.11
chr3_179415944_179416095 0.13 USP13
 ubiquitin specific peptidase 13 (isopeptidase T-3)
 23333
 0.19
chr12_125045629_125045780 0.13 NCOR2
 nuclear receptor corepressor 2
 6306
 0.32
chr2_165650853_165651004 0.13 COBLL1
 cordon-bleu WH2 repeat protein-like 1
 20664
 0.19
chr18_10899035_10899186 0.13 RP11-513M1.1
5495
 0.29
chr2_153446163_153446314 0.12 FMNL2
 formin-like 2
 29854
 0.24
chr5_148153495_148153674 0.12 ADRB2
 adrenoceptor beta 2, surface
 52572
 0.15
chrX_77829230_77829561 0.12 ZCCHC5
 zinc finger, CCHC domain containing 5
 85430
 0.1
chr9_80520526_80520677 0.12 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 82686
 0.11
chr17_55510110_55510261 0.12 ENSG00000263902
 .
 20623
 0.23
chr5_88113170_88113321 0.12 MEF2C
 myocyte enhancer factor 2C
 6360
 0.28
chr12_4386840_4387020 0.12 CCND2-AS1
 CCND2 antisense RNA 1
 1580
 0.28
chr13_30147951_30148102 0.12 SLC7A1
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
 12903
 0.28
chr8_125648788_125648939 0.12 RP11-532M24.1
56991
 0.12
chr15_38945205_38945356 0.12 C15orf53
 chromosome 15 open reading frame 53
 43519
 0.17
chr8_103092530_103092681 0.12 NCALD
 neurocalcin delta
 43573
 0.16
chr1_192796399_192796550 0.12 RGS2
 regulator of G-protein signaling 2, 24kDa
 18303
 0.23
chrX_48657873_48658024 0.12 HDAC6
 histone deacetylase 6
 1836
 0.2
chrX_15769905_15770141 0.12 CA5B
 carbonic anhydrase VB, mitochondrial
 1930
 0.32
chr17_1087827_1087978 0.12 ABR
 active BCR-related
 2714
 0.24
chr2_135438010_135438325 0.12 TMEM163
 transmembrane protein 163
 38403
 0.21
chr4_146542708_146542859 0.12 MMAA
 methylmalonic aciduria (cobalamin deficiency) cblA type
 3368
 0.26
chr22_47067865_47068016 0.12 GRAMD4
 GRAM domain containing 4
 2565
 0.33
chr14_104321166_104321317 0.12 PPP1R13B
 protein phosphatase 1, regulatory subunit 13B
 7314
 0.17
chr3_32864793_32864944 0.12 TRIM71
 tripartite motif containing 71, E3 ubiquitin protein ligase
 5358
 0.28
chr11_129201902_129202053 0.12 BARX2
 BARX homeobox 2
 43858
 0.17
chr6_13529066_13529217 0.12 ENSG00000202351
 .
 18795
 0.14
chr1_92812169_92812320 0.12 GLMN
 glomulin, FKBP associated protein
 47700
 0.12
chr10_18937367_18937518 0.12 NSUN6
 NOP2/Sun domain family, member 6
 3109
 0.24
chr2_182062690_182062873 0.12 ENSG00000266705
 .
 107598
 0.07
chr13_59042867_59043018 0.12 ENSG00000222733
 .
 58943
 0.17
chr14_59423768_59423919 0.12 ENSG00000221427
 .
 185879
 0.03
chr13_91864910_91865061 0.12 ENSG00000215417
 .
 137874
 0.05
chr6_41301582_41301834 0.12 NCR2
 natural cytotoxicity triggering receptor 2
 1685
 0.32
chr7_136611451_136611602 0.12 hsa-mir-490
 hsa-mir-490
 12477
 0.21
chr1_15500617_15500768 0.12 C1orf195
 chromosome 1 open reading frame 195
 2879
 0.29
chr4_79703843_79703994 0.12 BMP2K
 BMP2 inducible kinase
 6386
 0.2
chr20_11229977_11230245 0.12 C20orf187
 chromosome 20 open reading frame 187
 221300
 0.02
chr2_65132087_65132267 0.12 ENSG00000244534
 .
 2095
 0.28
chr20_1008398_1008549 0.12 RSPO4
 R-spondin 4
 25566
 0.2
chr2_62222707_62222858 0.12 COMMD1
 copper metabolism (Murr1) domain containing 1
 5332
 0.29
chr19_33236480_33236702 0.12 TDRD12
 tudor domain containing 12
 25612
 0.14
chr3_193952906_193953057 0.12 ENSG00000242201
 .
 89518
 0.07
chr5_31931833_31931984 0.12 ENSG00000266243
 .
 4357
 0.25
chr1_110703215_110703366 0.12 RP5-1028L10.1
6515
 0.13
chr9_131832684_131832835 0.12 DOLPP1
 dolichyldiphosphatase 1
 10620
 0.11
chr7_50363677_50363924 0.12 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 3445
 0.35
chr17_55457411_55457562 0.11 ENSG00000263902
 .
 32076
 0.2
chr4_88966383_88966534 0.11 PKD2
 polycystic kidney disease 2 (autosomal dominant)
 2045
 0.35
chr3_58886323_58886474 0.11 C3orf67
 chromosome 3 open reading frame 67
 37090
 0.2
chr8_50160983_50161134 0.11 ENSG00000199640
 .
 81711
 0.11
chr7_105495026_105495183 0.11 ATXN7L1
 ataxin 7-like 1
 21819
 0.26
chr1_37195687_37195944 0.11 RP4-614N24.1
42926
 0.19
chr7_114615058_114615617 0.11 MDFIC
 MyoD family inhibitor domain containing
 41413
 0.22
chr3_68139067_68139395 0.11 FAM19A1
 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
 83858
 0.11
chr12_98812168_98812319 0.11 ENSG00000201296
 .
 427
 0.88
chr5_56797760_56797911 0.11 ACTBL2
 actin, beta-like 2
 19199
 0.21
chr7_150542662_150542813 0.11 AOC1
 amine oxidase, copper containing 1
 6360
 0.19
chr5_10594062_10594213 0.11 ANKRD33B
 ankyrin repeat domain 33B
 29557
 0.17
chr1_204430993_204431895 0.11 PIK3C2B
 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
 5030
 0.21
chr5_58448897_58449048 0.11 RP11-266N13.2
113384
 0.07
chr5_78088517_78088668 0.11 LHFPL2
 lipoma HMGIC fusion partner-like 2
 143944
 0.05
chrX_135829438_135829709 0.11 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
 19929
 0.17
chr2_162815067_162815218 0.11 ENSG00000253046
 .
 39850
 0.19
chr2_192696442_192696593 0.11 AC098617.1
14748
 0.2
chr15_60359286_60359437 0.11 FOXB1
 forkhead box B1
 62940
 0.15
chr12_39267342_39267493 0.11 CPNE8
 copine VIII
 32016
 0.17
chr6_27235927_27236078 0.11 PRSS16
 protease, serine, 16 (thymus)
 19287
 0.18
chr4_22905571_22905722 0.11 GPR125
 G protein-coupled receptor 125
 387969
 0.01
chr9_113681977_113682128 0.11 ENSG00000207401
 .
 14634
 0.21
chr19_5119356_5119507 0.11 KDM4B
 lysine (K)-specific demethylase 4B
 36968
 0.16
chr7_142425935_142426150 0.11 PRSS1
 protease, serine, 1 (trypsin 1)
 31277
 0.16
chr10_71224348_71224499 0.11 TSPAN15
 tetraspanin 15
 13194
 0.21
chr20_37433246_37433545 0.11 PPP1R16B
 protein phosphatase 1, regulatory subunit 16B
 953
 0.57
chr17_16939284_16939435 0.11 MPRIP
 myosin phosphatase Rho interacting protein
 6500
 0.2
chr7_20278384_20278535 0.11 MACC1
 metastasis associated in colon cancer 1
 21432
 0.22
chr1_16024310_16024604 0.11 ENSG00000264048
 .
 13490
 0.1
chr7_139250491_139250642 0.11 CLEC2L
 C-type lectin domain family 2, member L
 41738
 0.17
chr15_38987903_38988075 0.11 C15orf53
 chromosome 15 open reading frame 53
 810
 0.76
chr9_139555674_139555825 0.11 RP11-251M1.1
876
 0.35
chr4_40154248_40154664 0.11 RP11-395I6.3
13839
 0.18
chr3_155364086_155364237 0.11 PLCH1
 phospholipase C, eta 1
 29667
 0.22
chr11_43399109_43399260 0.11 RP11-484D2.5
8037
 0.16
chr4_56753882_56754183 0.11 ENSG00000202358
 .
 2271
 0.3
chr5_61627825_61628088 0.11 KIF2A
 kinesin heavy chain member 2A
 20316
 0.22
chr11_117816071_117816391 0.11 TMPRSS13
 transmembrane protease, serine 13
 16057
 0.16
chr17_61505350_61505582 0.11 RP11-269G24.3
2984
 0.18
chr6_49630348_49630499 0.11 RHAG
 Rh-associated glycoprotein
 25871
 0.18
chr2_23726807_23726958 0.11 AC011239.1
 Uncharacterized protein
 20332
 0.27
chr2_60165263_60165480 0.11 ENSG00000252726
 .
 243474
 0.02
chr4_109280961_109281363 0.11 ENSG00000232021
 .
 183718
 0.03
chr12_27610504_27610655 0.11 SMCO2
 single-pass membrane protein with coiled-coil domains 2
 9164
 0.2
chr11_110341183_110341334 0.11 FDX1
 ferredoxin 1
 40651
 0.21
chr10_104373497_104373648 0.11 ENSG00000207029
 .
 22291
 0.14
chr9_90954471_90954622 0.11 ENSG00000252299
 .
 34638
 0.2
chr2_129394485_129394636 0.11 ENSG00000238379
 .
 191788
 0.03
chr9_126298972_126299123 0.11 RP11-230L22.4
44884
 0.15
chr15_78710532_78710683 0.11 IREB2
 iron-responsive element binding protein 2
 19166
 0.16
chr21_40351476_40351627 0.11 ENSG00000272015
 .
 84842
 0.09
chr13_27559343_27559515 0.11 USP12-AS1
 USP12 antisense RNA 1
 177563
 0.03
chr19_18140574_18140725 0.11 ARRDC2
 arrestin domain containing 2
 21672
 0.13
chr7_24931121_24931272 0.11 OSBPL3
 oxysterol binding protein-like 3
 998
 0.62
chr12_27171161_27171358 0.11 TM7SF3
 transmembrane 7 superfamily member 3
 3892
 0.18
chr8_20880900_20881051 0.11 ENSG00000215945
 .
 132667
 0.06
chr17_80436915_80437272 0.11 RP13-991F5.2
1293
 0.23
chr7_137683644_137683795 0.11 CREB3L2
 cAMP responsive element binding protein 3-like 2
 3074
 0.26
chrX_109389946_109390097 0.11 ENSG00000265584
 .
 64675
 0.11
chr3_111021000_111021297 0.11 CD96
 CD96 molecule
 9582
 0.3

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of TGIF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.0 GO:0043301 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.1 GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.1 GO:0001773 myeloid dendritic cell activation(GO:0001773)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.0 GO:1904063 negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.1 GO:0099738 cell cortex region(GO:0099738)
0.0 0.0 GO:0030904 retromer complex(GO:0030904)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.0 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis