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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for TGIF1

Z-value: 0.92

Motif logo

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Transcription factors associated with TGIF1

Gene Symbol Gene ID Gene Info
TGIF1
ENSG00000177426.16 TGIF1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
TGIF1chr18_3340712_3340863708190.0809680.627.6e-02Click!
TGIF1chr18_3459581_345973242440.247691-0.581.0e-01Click!
TGIF1chr18_3446975_34472434980.8192880.541.3e-01Click!
TGIF1chr18_3478848_3478999235110.181872-0.531.4e-01Click!
TGIF1chr18_3448954_34491053820.8774120.521.5e-01Click!

Activity of the TGIF1 motif across conditions

Conditions sorted by the z-value of the TGIF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_33208774_33208970 0.21 ITGB1
 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 11441
 0.29
chr22_36000465_36000757 0.21 MB
 myoglobin
 11149
 0.19
chr1_156196195_156196346 0.20 PMF1-BGLAP
 PMF1-BGLAP readthrough
 13470
 0.09
chr5_167532981_167533278 0.20 ENSG00000253065
 .
 72919
 0.1
chr21_34461417_34461568 0.19 AP000282.2
18082
 0.16
chr7_4166622_4166773 0.18 SDK1
 sidekick cell adhesion molecule 1
 176145
 0.03
chr1_156509588_156509739 0.18 ENSG00000238843
 .
 10541
 0.11
chr10_34004252_34004403 0.17 NRP1
 neuropilin 1
 379137
 0.01
chr4_48900915_48901066 0.17 OCIAD2
 OCIA domain containing 2
 7784
 0.2
chr21_41842867_41843018 0.17 ENSG00000207147
 .
 42129
 0.18
chr7_10018425_10018576 0.17 ENSG00000212422
 .
 243924
 0.02
chr9_90146510_90146661 0.17 DAPK1-IT1
 DAPK1 intronic transcript 1 (non-protein coding)
 21784
 0.22
chr8_19243061_19243460 0.16 SH2D4A
 SH2 domain containing 4A
 66159
 0.14
chr11_12194861_12195012 0.16 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 11233
 0.26
chr1_185135340_185135491 0.16 SWT1
 SWT1 RNA endoribonuclease homolog (S. cerevisiae)
 8801
 0.19
chr13_92002817_92003060 0.16 ENSG00000215417
 .
 59
 0.99
chr16_49534864_49535143 0.16 C16orf78
 chromosome 16 open reading frame 78
 127269
 0.05
chr2_45735351_45735502 0.16 SRBD1
 S1 RNA binding domain 1
 59728
 0.13
chr20_57601860_57602011 0.16 ATP5E
 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
 5412
 0.15
chr8_93693450_93693601 0.15 ENSG00000221172
 .
 45962
 0.18
chr2_207380556_207380707 0.15 ADAM23
 ADAM metallopeptidase domain 23
 72040
 0.1
chr5_56784424_56784602 0.15 ACTBL2
 actin, beta-like 2
 5877
 0.24
chr10_50390146_50390361 0.15 C10orf128
 chromosome 10 open reading frame 128
 6104
 0.2
chr16_68381624_68381775 0.15 ENSG00000222177
 .
 18267
 0.09
chr4_6013606_6013757 0.15 C4orf50
 chromosome 4 open reading frame 50
 22136
 0.24
chr3_168334920_168335071 0.15 ENSG00000207717
 .
 65353
 0.15
chr15_41925877_41926028 0.15 MGA
 MGA, MAX dimerization protein
 12218
 0.18
chr8_121016842_121017083 0.15 COL14A1
 collagen, type XIV, alpha 1
 100854
 0.07
chr7_40796116_40796267 0.15 AC005160.3
18966
 0.3
chr15_68634684_68634835 0.15 FEM1B
 fem-1 homolog b (C. elegans)
 52209
 0.13
chr9_113403073_113403248 0.15 MUSK
 muscle, skeletal, receptor tyrosine kinase
 27891
 0.21
chr11_44938433_44938696 0.15 TSPAN18
 tetraspanin 18
 10606
 0.25
chr3_16513920_16514071 0.14 RFTN1
 raftlin, lipid raft linker 1
 10377
 0.26
chr6_20564770_20564937 0.14 CDKAL1
 CDK5 regulatory subunit associated protein 1-like 1
 18281
 0.22
chr11_20029031_20029182 0.14 NAV2
 neuron navigator 2
 14996
 0.2
chr1_83171006_83171157 0.14 LPHN2
 latrophilin 2
 725508
 0.0
chr11_62321469_62322295 0.14 AHNAK
 AHNAK nucleoprotein
 1825
 0.17
chr6_109162296_109162639 0.14 ARMC2
 armadillo repeat containing 2
 7152
 0.28
chr1_145759757_145760123 0.14 PDZK1
 PDZ domain containing 1
 16677
 0.17
chr20_39561263_39561414 0.14 ENSG00000238908
 .
 78469
 0.1
chr13_21212008_21212159 0.14 ENSG00000222726
 .
 25783
 0.18
chr8_116661022_116661259 0.14 TRPS1
 trichorhinophalangeal syndrome I
 12765
 0.31
chr3_121590668_121590819 0.14 SLC15A2
 solute carrier family 15 (oligopeptide transporter), member 2
 22193
 0.15
chr6_161454710_161454940 0.14 MAP3K4
 mitogen-activated protein kinase kinase kinase 4
 11599
 0.25
chr6_82193288_82193439 0.14 RP1-300G12.2
51267
 0.16
chr11_95452659_95452810 0.14 FAM76B
 family with sequence similarity 76, member B
 67235
 0.12
chr1_157717360_157717511 0.14 FCRL2
 Fc receptor-like 2
 20129
 0.18
chr12_124230277_124230428 0.14 ATP6V0A2
 ATPase, H+ transporting, lysosomal V0 subunit a2
 4191
 0.2
chr9_12697396_12697547 0.14 TYRP1
 tyrosinase-related protein 1
 1751
 0.46
chr7_150360680_150361171 0.14 GIMAP2
 GTPase, IMAP family member 2
 21863
 0.15
chr13_103935436_103935587 0.14 SLC10A2
 solute carrier family 10 (sodium/bile acid cotransporter), member 2
 216315
 0.02
chr21_34426463_34426615 0.14 OLIG1
 oligodendrocyte transcription factor 1
 15911
 0.16
chr1_245084915_245085066 0.14 ENSG00000201758
 .
 22222
 0.14
chr15_82235742_82235893 0.14 ENSG00000222521
 .
 100818
 0.07
chr1_239701671_239701822 0.14 CHRM3
 cholinergic receptor, muscarinic 3
 90627
 0.1
chr21_26946893_26947044 0.14 ENSG00000234883
 .
 676
 0.69
chr4_159703546_159703697 0.14 ENSG00000206703
 .
 12227
 0.18
chr16_79449443_79449594 0.14 ENSG00000222244
 .
 151167
 0.04
chr14_70615527_70615823 0.14 SLC8A3
 solute carrier family 8 (sodium/calcium exchanger), member 3
 19526
 0.23
chr1_242012350_242012723 0.14 EXO1
 exonuclease 1
 283
 0.94
chr1_66556636_66556787 0.14 ENSG00000223152
 .
 3518
 0.3
chr1_168803043_168803442 0.14 ENSG00000221578
 .
 86122
 0.09
chr8_68632907_68633058 0.14 ENSG00000221660
 .
 9115
 0.21
chr2_176417653_176417879 0.14 ENSG00000221347
 .
 222665
 0.02
chr3_194838476_194838628 0.14 XXYLT1
 xyloside xylosyltransferase 1
 4369
 0.17
chr18_8455726_8455877 0.14 ENSG00000242985
 .
 16028
 0.18
chr17_27419224_27419375 0.14 TIAF1
 TGFB1-induced anti-apoptotic factor 1
 762
 0.58
chr19_16228666_16229162 0.13 RAB8A
 RAB8A, member RAS oncogene family
 6207
 0.14
chr9_80517904_80518204 0.13 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 80139
 0.11
chr6_6656190_6656366 0.13 LY86-AS1
 LY86 antisense RNA 1
 33274
 0.22
chr12_9921460_9921827 0.13 CD69
 CD69 molecule
 8146
 0.16
chr12_49213958_49214109 0.13 CACNB3
 calcium channel, voltage-dependent, beta 3 subunit
 1341
 0.26
chr4_116213074_116213225 0.13 NDST4
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
 178117
 0.03
chr2_165752418_165752569 0.13 ENSG00000223318
 .
 206
 0.94
chr16_23908795_23909009 0.13 PRKCB
 protein kinase C, beta
 60358
 0.13
chr6_13002773_13002924 0.13 PHACTR1
 phosphatase and actin regulator 1
 44634
 0.2
chr2_130569309_130569460 0.13 AC079776.2
113914
 0.06
chr12_68285414_68285565 0.13 IFNG-AS1
 IFNG antisense RNA 1
 97736
 0.09
chr15_38988151_38988528 0.13 C15orf53
 chromosome 15 open reading frame 53
 460
 0.89
chr18_53903146_53903297 0.13 ENSG00000201816
 .
 156396
 0.04
chr10_112478002_112478221 0.13 ENSG00000252036
 .
 38103
 0.13
chr17_49043165_49043316 0.13 SPAG9
 sperm associated antigen 9
 28058
 0.17
chr6_109660786_109660937 0.13 ENSG00000201023
 .
 34164
 0.12
chr6_45789023_45789174 0.13 ENSG00000252738
 .
 175257
 0.03
chr14_72595830_72595981 0.13 ENSG00000200298
 .
 106672
 0.07
chr7_101539600_101539793 0.13 CTB-181H17.1
63700
 0.11
chr11_42274588_42274739 0.13 LRRC4C
 leucine rich repeat containing 4C
 793340
 0.0
chr17_78845626_78846398 0.13 RPTOR
 regulatory associated protein of MTOR, complex 1
 50512
 0.1
chr14_49949021_49949172 0.13 ENSG00000252424
 .
 70255
 0.08
chr6_44796997_44797148 0.13 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
 126175
 0.06
chr17_1870594_1870879 0.13 CTD-2545H1.2
28172
 0.1
chr10_8374212_8374363 0.13 GATA3
 GATA binding protein 3
 277518
 0.01
chr3_138607537_138607828 0.13 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 53902
 0.11
chr3_179415944_179416095 0.13 USP13
 ubiquitin specific peptidase 13 (isopeptidase T-3)
 23333
 0.19
chr12_125045629_125045780 0.13 NCOR2
 nuclear receptor corepressor 2
 6306
 0.32
chr2_165650853_165651004 0.13 COBLL1
 cordon-bleu WH2 repeat protein-like 1
 20664
 0.19
chr18_10899035_10899186 0.13 RP11-513M1.1
5495
 0.29
chr2_153446163_153446314 0.12 FMNL2
 formin-like 2
 29854
 0.24
chr5_148153495_148153674 0.12 ADRB2
 adrenoceptor beta 2, surface
 52572
 0.15
chrX_77829230_77829561 0.12 ZCCHC5
 zinc finger, CCHC domain containing 5
 85430
 0.1
chr9_80520526_80520677 0.12 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 82686
 0.11
chr17_55510110_55510261 0.12 ENSG00000263902
 .
 20623
 0.23
chr5_88113170_88113321 0.12 MEF2C
 myocyte enhancer factor 2C
 6360
 0.28
chr12_4386840_4387020 0.12 CCND2-AS1
 CCND2 antisense RNA 1
 1580
 0.28
chr13_30147951_30148102 0.12 SLC7A1
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
 12903
 0.28
chr8_125648788_125648939 0.12 RP11-532M24.1
56991
 0.12
chr15_38945205_38945356 0.12 C15orf53
 chromosome 15 open reading frame 53
 43519
 0.17
chr8_103092530_103092681 0.12 NCALD
 neurocalcin delta
 43573
 0.16
chr1_192796399_192796550 0.12 RGS2
 regulator of G-protein signaling 2, 24kDa
 18303
 0.23
chrX_48657873_48658024 0.12 HDAC6
 histone deacetylase 6
 1836
 0.2
chrX_15769905_15770141 0.12 CA5B
 carbonic anhydrase VB, mitochondrial
 1930
 0.32
chr17_1087827_1087978 0.12 ABR
 active BCR-related
 2714
 0.24
chr2_135438010_135438325 0.12 TMEM163
 transmembrane protein 163
 38403
 0.21
chr4_146542708_146542859 0.12 MMAA
 methylmalonic aciduria (cobalamin deficiency) cblA type
 3368
 0.26
chr22_47067865_47068016 0.12 GRAMD4
 GRAM domain containing 4
 2565
 0.33
chr14_104321166_104321317 0.12 PPP1R13B
 protein phosphatase 1, regulatory subunit 13B
 7314
 0.17
chr3_32864793_32864944 0.12 TRIM71
 tripartite motif containing 71, E3 ubiquitin protein ligase
 5358
 0.28
chr11_129201902_129202053 0.12 BARX2
 BARX homeobox 2
 43858
 0.17
chr6_13529066_13529217 0.12 ENSG00000202351
 .
 18795
 0.14
chr1_92812169_92812320 0.12 GLMN
 glomulin, FKBP associated protein
 47700
 0.12
chr10_18937367_18937518 0.12 NSUN6
 NOP2/Sun domain family, member 6
 3109
 0.24
chr2_182062690_182062873 0.12 ENSG00000266705
 .
 107598
 0.07
chr13_59042867_59043018 0.12 ENSG00000222733
 .
 58943
 0.17
chr14_59423768_59423919 0.12 ENSG00000221427
 .
 185879
 0.03
chr13_91864910_91865061 0.12 ENSG00000215417
 .
 137874
 0.05
chr6_41301582_41301834 0.12 NCR2
 natural cytotoxicity triggering receptor 2
 1685
 0.32
chr7_136611451_136611602 0.12 hsa-mir-490
 hsa-mir-490
 12477
 0.21
chr1_15500617_15500768 0.12 C1orf195
 chromosome 1 open reading frame 195
 2879
 0.29
chr4_79703843_79703994 0.12 BMP2K
 BMP2 inducible kinase
 6386
 0.2
chr20_11229977_11230245 0.12 C20orf187
 chromosome 20 open reading frame 187
 221300
 0.02
chr2_65132087_65132267 0.12 ENSG00000244534
 .
 2095
 0.28
chr20_1008398_1008549 0.12 RSPO4
 R-spondin 4
 25566
 0.2
chr2_62222707_62222858 0.12 COMMD1
 copper metabolism (Murr1) domain containing 1
 5332
 0.29
chr19_33236480_33236702 0.12 TDRD12
 tudor domain containing 12
 25612
 0.14
chr3_193952906_193953057 0.12 ENSG00000242201
 .
 89518
 0.07
chr5_31931833_31931984 0.12 ENSG00000266243
 .
 4357
 0.25
chr1_110703215_110703366 0.12 RP5-1028L10.1
6515
 0.13
chr9_131832684_131832835 0.12 DOLPP1
 dolichyldiphosphatase 1
 10620
 0.11
chr7_50363677_50363924 0.12 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 3445
 0.35
chr17_55457411_55457562 0.11 ENSG00000263902
 .
 32076
 0.2
chr4_88966383_88966534 0.11 PKD2
 polycystic kidney disease 2 (autosomal dominant)
 2045
 0.35
chr3_58886323_58886474 0.11 C3orf67
 chromosome 3 open reading frame 67
 37090
 0.2
chr8_50160983_50161134 0.11 ENSG00000199640
 .
 81711
 0.11
chr7_105495026_105495183 0.11 ATXN7L1
 ataxin 7-like 1
 21819
 0.26
chr1_37195687_37195944 0.11 RP4-614N24.1
42926
 0.19
chr7_114615058_114615617 0.11 MDFIC
 MyoD family inhibitor domain containing
 41413
 0.22
chr3_68139067_68139395 0.11 FAM19A1
 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1
 83858
 0.11
chr12_98812168_98812319 0.11 ENSG00000201296
 .
 427
 0.88
chr5_56797760_56797911 0.11 ACTBL2
 actin, beta-like 2
 19199
 0.21
chr7_150542662_150542813 0.11 AOC1
 amine oxidase, copper containing 1
 6360
 0.19
chr5_10594062_10594213 0.11 ANKRD33B
 ankyrin repeat domain 33B
 29557
 0.17
chr1_204430993_204431895 0.11 PIK3C2B
 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
 5030
 0.21
chr5_58448897_58449048 0.11 RP11-266N13.2
113384
 0.07
chr5_78088517_78088668 0.11 LHFPL2
 lipoma HMGIC fusion partner-like 2
 143944
 0.05
chrX_135829438_135829709 0.11 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
 19929
 0.17
chr2_162815067_162815218 0.11 ENSG00000253046
 .
 39850
 0.19
chr2_192696442_192696593 0.11 AC098617.1
14748
 0.2
chr15_60359286_60359437 0.11 FOXB1
 forkhead box B1
 62940
 0.15
chr12_39267342_39267493 0.11 CPNE8
 copine VIII
 32016
 0.17
chr6_27235927_27236078 0.11 PRSS16
 protease, serine, 16 (thymus)
 19287
 0.18
chr4_22905571_22905722 0.11 GPR125
 G protein-coupled receptor 125
 387969
 0.01
chr9_113681977_113682128 0.11 ENSG00000207401
 .
 14634
 0.21
chr19_5119356_5119507 0.11 KDM4B
 lysine (K)-specific demethylase 4B
 36968
 0.16
chr7_142425935_142426150 0.11 PRSS1
 protease, serine, 1 (trypsin 1)
 31277
 0.16
chr10_71224348_71224499 0.11 TSPAN15
 tetraspanin 15
 13194
 0.21
chr20_37433246_37433545 0.11 PPP1R16B
 protein phosphatase 1, regulatory subunit 16B
 953
 0.57
chr17_16939284_16939435 0.11 MPRIP
 myosin phosphatase Rho interacting protein
 6500
 0.2
chr7_20278384_20278535 0.11 MACC1
 metastasis associated in colon cancer 1
 21432
 0.22
chr1_16024310_16024604 0.11 ENSG00000264048
 .
 13490
 0.1
chr7_139250491_139250642 0.11 CLEC2L
 C-type lectin domain family 2, member L
 41738
 0.17
chr15_38987903_38988075 0.11 C15orf53
 chromosome 15 open reading frame 53
 810
 0.76
chr9_139555674_139555825 0.11 RP11-251M1.1
876
 0.35
chr4_40154248_40154664 0.11 RP11-395I6.3
13839
 0.18
chr3_155364086_155364237 0.11 PLCH1
 phospholipase C, eta 1
 29667
 0.22
chr11_43399109_43399260 0.11 RP11-484D2.5
8037
 0.16
chr4_56753882_56754183 0.11 ENSG00000202358
 .
 2271
 0.3
chr5_61627825_61628088 0.11 KIF2A
 kinesin heavy chain member 2A
 20316
 0.22
chr11_117816071_117816391 0.11 TMPRSS13
 transmembrane protease, serine 13
 16057
 0.16
chr17_61505350_61505582 0.11 RP11-269G24.3
2984
 0.18
chr6_49630348_49630499 0.11 RHAG
 Rh-associated glycoprotein
 25871
 0.18
chr2_23726807_23726958 0.11 AC011239.1
 Uncharacterized protein
 20332
 0.27
chr2_60165263_60165480 0.11 ENSG00000252726
 .
 243474
 0.02
chr4_109280961_109281363 0.11 ENSG00000232021
 .
 183718
 0.03
chr12_27610504_27610655 0.11 SMCO2
 single-pass membrane protein with coiled-coil domains 2
 9164
 0.2
chr11_110341183_110341334 0.11 FDX1
 ferredoxin 1
 40651
 0.21
chr10_104373497_104373648 0.11 ENSG00000207029
 .
 22291
 0.14
chr9_90954471_90954622 0.11 ENSG00000252299
 .
 34638
 0.2
chr2_129394485_129394636 0.11 ENSG00000238379
 .
 191788
 0.03
chr9_126298972_126299123 0.11 RP11-230L22.4
44884
 0.15
chr15_78710532_78710683 0.11 IREB2
 iron-responsive element binding protein 2
 19166
 0.16
chr21_40351476_40351627 0.11 ENSG00000272015
 .
 84842
 0.09
chr13_27559343_27559515 0.11 USP12-AS1
 USP12 antisense RNA 1
 177563
 0.03
chr19_18140574_18140725 0.11 ARRDC2
 arrestin domain containing 2
 21672
 0.13
chr7_24931121_24931272 0.11 OSBPL3
 oxysterol binding protein-like 3
 998
 0.62
chr12_27171161_27171358 0.11 TM7SF3
 transmembrane 7 superfamily member 3
 3892
 0.18
chr8_20880900_20881051 0.11 ENSG00000215945
 .
 132667
 0.06
chr17_80436915_80437272 0.11 RP13-991F5.2
1293
 0.23
chr7_137683644_137683795 0.11 CREB3L2
 cAMP responsive element binding protein 3-like 2
 3074
 0.26
chrX_109389946_109390097 0.11 ENSG00000265584
 .
 64675
 0.11
chr3_111021000_111021297 0.11 CD96
 CD96 molecule
 9582
 0.3

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of TGIF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.0 GO:0043301 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.1 GO:0002420 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.1 GO:0001773 myeloid dendritic cell activation(GO:0001773)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.1 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.0 GO:1904063 negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.1 GO:0099738 cell cortex region(GO:0099738)
0.0 0.0 GO:0030904 retromer complex(GO:0030904)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.0 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.0 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis