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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for THRA_RXRB

Z-value: 1.35

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Transcription factors associated with THRA_RXRB

Gene Symbol Gene ID Gene Info
THRA
ENSG00000126351.8 thyroid hormone receptor alpha
RXRB
ENSG00000204231.6 retinoid X receptor beta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_38218268_38218459THRA830.9206850.713.3e-02Click!
chr17_38229780_38229931THRA15110.2740480.703.5e-02Click!
chr17_38218492_38218643THRA1210.9141710.608.7e-02Click!
chr17_38232565_38232716THRA42960.1368260.571.1e-01Click!
chr17_38223510_38223773THRA15150.2711840.511.6e-01Click!

Activity of the THRA_RXRB motif across conditions

Conditions sorted by the z-value of the THRA_RXRB motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_107819281_107819678 0.72 CD47
 CD47 molecule
 9607
 0.3
chr2_127422232_127422532 0.53 GYPC
 glycophorin C (Gerbich blood group)
 8622
 0.27
chr15_78336776_78336956 0.50 ENSG00000221476
 .
 5993
 0.15
chr7_150453228_150453688 0.47 GIMAP5
 GTPase, IMAP family member 5
 19022
 0.14
chr6_36647112_36647373 0.44 CDKN1A
 cyclin-dependent kinase inhibitor 1A (p21, Cip1)
 744
 0.58
chr3_13023386_13023537 0.44 IQSEC1
 IQ motif and Sec7 domain 1
 5075
 0.29
chr10_129678837_129678988 0.44 CLRN3
 clarin 3
 12299
 0.22
chr2_7050734_7050964 0.43 RNF144A
 ring finger protein 144A
 6674
 0.18
chr15_85264382_85264668 0.42 SEC11A
 SEC11 homolog A (S. cerevisiae)
 4578
 0.15
chr11_118099433_118099584 0.42 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 3699
 0.17
chrX_48543101_48543693 0.41 WAS
 Wiskott-Aldrich syndrome
 1229
 0.35
chr20_2722949_2723333 0.41 EBF4
 early B-cell factor 4
 36254
 0.09
chr17_66344922_66345112 0.41 ARSG
 arylsulfatase G
 57358
 0.1
chr1_200854769_200854937 0.39 C1orf106
 chromosome 1 open reading frame 106
 5323
 0.19
chr6_116785564_116786071 0.39 RP1-93H18.6
962
 0.41
chr17_8859556_8859835 0.39 PIK3R5
 phosphoinositide-3-kinase, regulatory subunit 5
 9329
 0.24
chr17_75913110_75913444 0.38 ENSG00000238898
 .
 2903
 0.3
chr5_126308801_126309244 0.38 MARCH3
 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
 55102
 0.15
chr12_124491346_124491497 0.38 ZNF664
 zinc finger protein 664
 33579
 0.08
chr12_93981713_93981864 0.38 SOCS2
 suppressor of cytokine signaling 2
 12954
 0.18
chr5_126312253_126312404 0.38 MARCH3
 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
 54172
 0.15
chr17_75840839_75841130 0.38 FLJ45079
37675
 0.18
chr21_44010697_44010940 0.38 AP001625.6
28774
 0.14
chr1_155916745_155916975 0.37 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
 4679
 0.1
chr2_174328085_174328236 0.37 CDCA7
 cell division cycle associated 7
 108560
 0.07
chr3_107791032_107791183 0.37 CD47
 CD47 molecule
 12728
 0.3
chr4_38916757_38916925 0.37 ENSG00000207944
 .
 47188
 0.11
chr6_159461814_159462217 0.37 TAGAP
 T-cell activation RhoGTPase activating protein
 4035
 0.22
chr8_144939517_144939748 0.36 EPPK1
 epiplakin 1
 13000
 0.09
chr16_84641040_84641383 0.36 COTL1
 coactosin-like 1 (Dictyostelium)
 10454
 0.17
chr15_70744544_70744849 0.36 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 249924
 0.02
chr2_10518114_10518365 0.36 HPCAL1
 hippocalcin-like 1
 41908
 0.14
chr16_30468718_30468869 0.36 ENSG00000202476
 .
 3375
 0.08
chr8_42000299_42000484 0.36 RP11-589C21.5
9890
 0.17
chr3_150888432_150888616 0.36 ENSG00000199994
 .
 17362
 0.16
chr5_176783043_176783194 0.36 RGS14
 regulator of G-protein signaling 14
 1720
 0.2
chrX_128921545_128921805 0.35 SASH3
 SAM and SH3 domain containing 3
 7715
 0.2
chr1_1830831_1831010 0.35 RP1-140A9.1
8010
 0.13
chr9_86908771_86909182 0.35 RP11-380F14.2
15842
 0.25
chr2_99087636_99087787 0.35 INPP4A
 inositol polyphosphate-4-phosphatase, type I, 107kDa
 26298
 0.2
chr2_198072900_198073187 0.34 ANKRD44
 ankyrin repeat domain 44
 10281
 0.21
chr16_29672717_29672868 0.34 SPN
 sialophorin
 1508
 0.26
chr14_90148740_90149294 0.34 ENSG00000200312
 .
 29838
 0.14
chr1_169574716_169574995 0.34 SELP
 selectin P (granule membrane protein 140kDa, antigen CD62)
 13602
 0.2
chr5_132483935_132484150 0.34 CTB-49A3.2
12088
 0.22
chr15_76222456_76222700 0.34 FBXO22
 F-box protein 22
 2563
 0.27
chr8_135324203_135324532 0.34 ZFAT
 zinc finger and AT hook domain containing
 198058
 0.03
chr13_100071950_100072184 0.33 ENSG00000266207
 .
 33656
 0.15
chr1_109188369_109188646 0.33 HENMT1
 HEN1 methyltransferase homolog 1 (Arabidopsis)
 15170
 0.19
chr7_138731189_138731354 0.33 ZC3HAV1L
 zinc finger CCCH-type, antiviral 1-like
 10496
 0.21
chr3_39300527_39300690 0.33 CX3CR1
 chemokine (C-X3-C motif) receptor 1
 20917
 0.18
chr7_150359146_150359387 0.33 GIMAP2
 GTPase, IMAP family member 2
 23522
 0.15
chr14_100546662_100546850 0.33 CTD-2376I20.1
5541
 0.16
chr14_104855874_104856139 0.33 ENSG00000222761
 .
 11379
 0.26
chr5_133467618_133467806 0.33 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 8403
 0.21
chr17_56247502_56247750 0.33 OR4D2
 olfactory receptor, family 4, subfamily D, member 2
 609
 0.66
chr1_9717399_9717821 0.33 C1orf200
 chromosome 1 open reading frame 200
 2966
 0.22
chr6_90793986_90794257 0.32 ENSG00000222078
 .
 82896
 0.09
chr1_236101876_236102050 0.32 ENSG00000206803
 .
 23248
 0.18
chr15_91372602_91372985 0.32 CTD-3094K11.1
10161
 0.13
chr9_135992327_135992532 0.32 RALGDS
 ral guanine nucleotide dissociation stimulator
 4134
 0.16
chr7_37393575_37393854 0.32 ELMO1
 engulfment and cell motility 1
 442
 0.83
chr11_67414919_67415070 0.32 ACY3
 aspartoacylase (aminocyclase) 3
 60
 0.95
chr11_63973377_63973615 0.32 FERMT3
 fermitin family member 3
 654
 0.44
chr15_64750062_64750402 0.32 ZNF609
 zinc finger protein 609
 2709
 0.18
chr2_135433313_135433464 0.31 TMEM163
 transmembrane protein 163
 43182
 0.2
chr6_34250869_34251020 0.31 C6orf1
 chromosome 6 open reading frame 1
 33697
 0.16
chr1_154464906_154465057 0.31 SHE
 Src homology 2 domain containing E
 3339
 0.16
chr5_39155242_39155486 0.31 FYB
 FYN binding protein
 47765
 0.15
chr3_50636542_50636693 0.31 CISH
 cytokine inducible SH2-containing protein
 12586
 0.14
chr16_67586263_67586449 0.31 FAM65A
 family with sequence similarity 65, member A
 8059
 0.09
chr5_10505521_10505706 0.31 RP11-1C1.5
 Uncharacterized protein
 3693
 0.21
chr10_104830143_104830341 0.31 NT5C2
 5'-nucleotidase, cytosolic II
 23883
 0.21
chr6_159454655_159454806 0.31 RP1-111C20.4
7752
 0.19
chr15_29228523_29228674 0.31 APBA2
 amyloid beta (A4) precursor protein-binding, family A, member 2
 14758
 0.23
chr2_27109662_27109955 0.31 DPYSL5
 dihydropyrimidinase-like 5
 38432
 0.13
chr16_57175250_57175426 0.31 CPNE2
 copine II
 22227
 0.12
chr4_124538385_124538719 0.31 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 217429
 0.02
chr9_117144402_117144633 0.31 AKNA
 AT-hook transcription factor
 4602
 0.23
chr7_50357344_50357742 0.31 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 9225
 0.29
chr18_60198457_60198694 0.31 ZCCHC2
 zinc finger, CCHC domain containing 2
 7723
 0.28
chr1_47654400_47654551 0.31 PDZK1IP1
 PDZK1 interacting protein 1
 1252
 0.4
chr2_8519563_8519714 0.31 AC011747.7
296258
 0.01
chr22_39296706_39296951 0.31 CBX6
 chromobox homolog 6
 28509
 0.12
chr3_46416206_46416357 0.30 CCR5
 chemokine (C-C motif) receptor 5 (gene/pseudogene)
 2120
 0.26
chr22_40798855_40799170 0.30 SGSM3
 small G protein signaling modulator 3
 5305
 0.17
chr1_167570221_167570504 0.30 RCSD1
 RCSD domain containing 1
 28968
 0.15
chr19_49838163_49838543 0.30 CD37
 CD37 molecule
 300
 0.78
chr19_7402225_7402456 0.30 CTB-133G6.1
11508
 0.16
chr11_44936863_44937276 0.30 TSPAN18
 tetraspanin 18
 9111
 0.25
chr6_37485958_37486109 0.30 CCDC167
 coiled-coil domain containing 167
 18335
 0.19
chr2_8716699_8716875 0.30 AC011747.7
99109
 0.08
chr2_158278417_158278728 0.30 CYTIP
 cytohesin 1 interacting protein
 17354
 0.21
chr13_110222272_110222771 0.29 LINC00676
 long intergenic non-protein coding RNA 676
 158108
 0.04
chr1_12233372_12233638 0.29 TNFRSF1B
 tumor necrosis factor receptor superfamily, member 1B
 6445
 0.17
chr14_93533102_93533332 0.29 ITPK1
 inositol-tetrakisphosphate 1-kinase
 514
 0.5
chr8_24134022_24134173 0.29 ADAM28
 ADAM metallopeptidase domain 28
 17456
 0.26
chr8_6584199_6584352 0.29 AGPAT5
 1-acylglycerol-3-phosphate O-acyltransferase 5
 18061
 0.17
chr5_53912958_53913109 0.29 SNX18
 sorting nexin 18
 99440
 0.08
chr1_198529109_198529554 0.29 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
 19256
 0.26
chr4_2837237_2837388 0.29 ADD1
 adducin 1 (alpha)
 8272
 0.19
chr2_16105641_16106067 0.29 ENSG00000243541
 .
 14751
 0.18
chr22_45028998_45029149 0.29 PRR5
 proline rich 5 (renal)
 35520
 0.18
chr3_178793021_178793370 0.29 ZMAT3
 zinc finger, matrin-type 3
 3128
 0.27
chr14_61911054_61911390 0.29 PRKCH
 protein kinase C, eta
 1946
 0.42
chr17_76779813_76780089 0.29 CYTH1
 cytohesin 1
 1572
 0.38
chr7_73630981_73631230 0.29 LAT2
 linker for activation of T cells family, member 2
 6752
 0.16
chr1_247336048_247336203 0.29 ZNF124
 zinc finger protein 124
 807
 0.56
chr10_73494821_73495244 0.29 C10orf105
 chromosome 10 open reading frame 105
 2549
 0.3
chr22_24058094_24058402 0.29 AP000347.2
1234
 0.32
chr2_43610834_43610985 0.29 ENSG00000252804
 .
 24537
 0.25
chr22_23134104_23134282 0.28 ENSG00000207833
 .
 784
 0.23
chr9_132658123_132658578 0.28 FNBP1
 formin binding protein 1
 23239
 0.15
chr20_39780023_39780174 0.28 RP1-1J6.2
13455
 0.19
chr11_3969138_3969471 0.28 STIM1
 stromal interaction molecule 1
 731
 0.66
chr5_75720501_75720652 0.28 IQGAP2
 IQ motif containing GTPase activating protein 2
 20327
 0.26
chr11_48039113_48039300 0.28 AC103828.1
1799
 0.39
chr5_171333279_171333614 0.28 FBXW11
 F-box and WD repeat domain containing 11
 71314
 0.11
chr1_227936240_227936391 0.28 SNAP47
 synaptosomal-associated protein, 47kDa
 551
 0.67
chr2_198167309_198167571 0.28 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 197
 0.93
chr14_93134593_93134845 0.28 RIN3
 Ras and Rab interactor 3
 15873
 0.24
chr14_28295050_28295241 0.28 ENSG00000223164
 .
 164066
 0.04
chr7_132118427_132118619 0.28 AC011625.1
81430
 0.1
chr17_74269143_74269364 0.28 QRICH2
 glutamine rich 2
 7185
 0.13
chr5_141282643_141282794 0.28 KIAA0141
 KIAA0141
 20655
 0.14
chr8_6287473_6287678 0.28 RP11-115C21.2
22912
 0.21
chr20_31111792_31112136 0.28 C20orf112
 chromosome 20 open reading frame 112
 3307
 0.23
chr14_21269173_21269324 0.28 RNASE1
 ribonuclease, RNase A family, 1 (pancreatic)
 1317
 0.31
chr10_7525377_7526075 0.28 ENSG00000207453
 .
 3045
 0.32
chr4_185683459_185683704 0.28 ACSL1
 acyl-CoA synthetase long-chain family member 1
 4275
 0.22
chr1_100877624_100878071 0.28 ENSG00000216067
 .
 33516
 0.16
chr8_134086193_134086434 0.28 SLA
 Src-like-adaptor
 13710
 0.23
chr6_53209989_53210148 0.27 ELOVL5
 ELOVL fatty acid elongase 5
 3519
 0.27
chr17_7454664_7454994 0.27 TNFSF12
 tumor necrosis factor (ligand) superfamily, member 12
 2358
 0.08
chr17_63022313_63022486 0.27 RP11-583F2.5
25628
 0.14
chr5_118619331_118619759 0.27 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
 15096
 0.18
chr3_43298637_43298793 0.27 SNRK
 SNF related kinase
 29289
 0.16
chr15_91228796_91228947 0.27 RP11-387D10.3
24901
 0.13
chr14_61827530_61827767 0.27 PRKCH
 protein kinase C, eta
 144
 0.97
chr1_9486742_9486893 0.27 ENSG00000252956
 .
 11020
 0.24
chr20_48969794_48969957 0.27 ENSG00000244376
 .
 76145
 0.1
chr14_91544790_91544971 0.27 ENSG00000252644
 .
 12541
 0.16
chr3_141989336_141989501 0.27 GK5
 glycerol kinase 5 (putative)
 44969
 0.16
chr13_114817282_114817433 0.27 RASA3
 RAS p21 protein activator 3
 26081
 0.22
chr16_3627581_3627750 0.27 NLRC3
 NLR family, CARD domain containing 3
 264
 0.89
chr16_30392632_30392982 0.27 SEPT1
 septin 1
 945
 0.31
chr12_132663008_132663169 0.27 GALNT9
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
 27249
 0.14
chr16_50196893_50197200 0.27 PAPD5
 PAP associated domain containing 5
 9267
 0.16
chr9_101900893_101901046 0.27 ENSG00000252942
 .
 7279
 0.19
chr9_2023792_2024048 0.27 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 1975
 0.41
chr19_8632582_8633028 0.27 MYO1F
 myosin IF
 9517
 0.11
chr7_37461432_37461682 0.27 ENSG00000200113
 .
 2326
 0.3
chr14_105750101_105750417 0.27 BRF1
 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
 16546
 0.15
chr19_17514773_17515020 0.27 BST2
 bone marrow stromal cell antigen 2
 1561
 0.17
chr22_23164320_23164502 0.26 IGLV2-8
 immunoglobulin lambda variable 2-8
 742
 0.25
chr6_158306516_158306953 0.26 RP3-403L10.3
7084
 0.18
chr7_7963215_7963560 0.26 ENSG00000201747
 .
 17237
 0.17
chr14_22964920_22965173 0.26 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 8875
 0.1
chr1_206733046_206733294 0.26 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 2677
 0.24
chr22_39920591_39920772 0.26 ATF4
 activating transcription factor 4
 4112
 0.17
chr1_55668824_55669013 0.26 USP24
 ubiquitin specific peptidase 24
 11844
 0.22
chr6_109770732_109770883 0.26 MICAL1
 microtubule associated monooxygenase, calponin and LIM domain containing 1
 179
 0.91
chr1_167452877_167453134 0.26 RP11-104L21.2
25107
 0.17
chr7_139468099_139468250 0.26 HIPK2
 homeodomain interacting protein kinase 2
 9343
 0.23
chr11_48065545_48066080 0.26 AC103828.1
28405
 0.17
chr17_72636963_72637310 0.26 CD300E
 CD300e molecule
 17239
 0.12
chr5_142178337_142178630 0.26 ARHGAP26
 Rho GTPase activating protein 26
 26201
 0.22
chr6_106324555_106324706 0.26 ENSG00000200198
 .
 27618
 0.26
chr3_34060384_34060651 0.26 PDCD6IP
 programmed cell death 6 interacting protein
 220402
 0.02
chr1_247367941_247368092 0.26 ENSG00000252516
 .
 53
 0.96
chr8_71053263_71053636 0.26 NCOA2
 nuclear receptor coactivator 2
 7172
 0.25
chr5_67527341_67527547 0.26 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 4982
 0.28
chr12_108714499_108714650 0.26 CMKLR1
 chemokine-like receptor 1
 135
 0.98
chr6_143865508_143865659 0.26 PHACTR2
 phosphatase and actin regulator 2
 7601
 0.17
chr18_3723612_3723763 0.25 RP11-874J12.3
47743
 0.13
chr18_43589850_43590001 0.25 ENSG00000222179
 .
 20014
 0.17
chr1_154987014_154987262 0.25 ZBTB7B
 zinc finger and BTB domain containing 7B
 214
 0.83
chr18_21549060_21549211 0.25 LAMA3
 laminin, alpha 3
 19278
 0.17
chr8_37553639_37554052 0.25 ZNF703
 zinc finger protein 703
 576
 0.66
chr6_157140981_157141263 0.25 RP11-230C9.3
39533
 0.16
chr16_31497874_31498025 0.25 AC026471.6
1864
 0.17
chr1_172694568_172694750 0.25 FASLG
 Fas ligand (TNF superfamily, member 6)
 66501
 0.13
chr19_12442067_12442220 0.25 ZNF563
 zinc finger protein 563
 2163
 0.24
chr22_43659141_43659490 0.25 SCUBE1
 signal peptide, CUB domain, EGF-like 1
 510
 0.76
chr1_86907105_86907371 0.25 CLCA2
 chloride channel accessory 2
 17469
 0.19
chr1_66773813_66773964 0.25 PDE4B
 phosphodiesterase 4B, cAMP-specific
 22523
 0.27
chr1_100830416_100830661 0.25 CDC14A
 cell division cycle 14A
 12033
 0.18
chr13_84712610_84712776 0.25 SLITRK1
 SLIT and NTRK-like family, member 1
 256165
 0.02
chr5_176859524_176860060 0.25 GRK6
 G protein-coupled receptor kinase 6
 5937
 0.1
chr15_31728916_31729103 0.25 KLF13
 Kruppel-like factor 13
 70652
 0.13
chr2_218884404_218884588 0.25 TNS1
 tensin 1
 16778
 0.16
chr20_55097345_55097496 0.25 FAM209A
 family with sequence similarity 209, member A
 2122
 0.22
chr17_26070911_26071062 0.25 ENSG00000263472
 .
 41048
 0.13
chr9_95822386_95822880 0.25 SUSD3
 sushi domain containing 3
 1572
 0.37
chr1_112887579_112887730 0.25 ENSG00000238761
 .
 25972
 0.2
chr1_1074452_1074741 0.25 C1orf159
 chromosome 1 open reading frame 159
 22855
 0.07
chr4_2789296_2789952 0.25 SH3BP2
 SH3-domain binding protein 2
 5126
 0.22
chr2_103511305_103511456 0.25 TMEM182
 transmembrane protein 182
 132908
 0.05
chr10_91498741_91498892 0.25 KIF20B
 kinesin family member 20B
 37380
 0.18
chr2_99090097_99090281 0.25 INPP4A
 inositol polyphosphate-4-phosphatase, type I, 107kDa
 28776
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of THRA_RXRB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.3 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:0045056 transcytosis(GO:0045056)
0.1 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.3 GO:0045588 regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588)
0.1 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:0033622 integrin activation(GO:0033622)
0.1 0.2 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.5 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.1 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.2 GO:0097576 vacuole fusion(GO:0097576)
0.1 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.0 0.2 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0002664 T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.0 0.4 GO:0015884 folic acid transport(GO:0015884)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.4 GO:0002418 immune response to tumor cell(GO:0002418)
0.0 0.1 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.1 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.6 GO:0002639 positive regulation of immunoglobulin production(GO:0002639)
0.0 0.2 GO:0001562 response to protozoan(GO:0001562)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.2 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.4 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.3 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.5 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0051132 NK T cell activation(GO:0051132)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.1 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.0 0.1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.2 GO:0032367 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.3 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.0 GO:0002227 innate immune response in mucosa(GO:0002227) mucosal immune response(GO:0002385)
0.0 0.4 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0031529 ruffle organization(GO:0031529)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.2 GO:0051647 nucleus localization(GO:0051647)
0.0 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.2 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0 0.2 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0 0.1 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.4 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.9 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0031442 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.0 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0070723 response to sterol(GO:0036314) response to cholesterol(GO:0070723)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.0 GO:0090286 nuclear matrix organization(GO:0043578) cytoskeletal anchoring at nuclear membrane(GO:0090286) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.0 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.0 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.1 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0002251 organ or tissue specific immune response(GO:0002251)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.0 GO:0032971 regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0 0.1 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.0 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.0 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0031063 regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.0 0.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.1 GO:0010288 response to lead ion(GO:0010288)
0.0 0.0 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.0 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.2 GO:0070192 synapsis(GO:0007129) chromosome organization involved in meiotic cell cycle(GO:0070192)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0060557 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.0 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.0 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.0 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:0007032 endosome organization(GO:0007032)
0.0 0.0 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.0 0.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.0 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.0 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.0 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.0 GO:0097384 cellular lipid biosynthetic process(GO:0097384)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.0 GO:0031058 positive regulation of histone modification(GO:0031058)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.0 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.0 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.0 GO:0051818 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.1 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:0031904 endosome lumen(GO:0031904)
0.1 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.2 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.0 GO:0038201 TOR complex(GO:0038201)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.0 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.0 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.1 0.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.8 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.3 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.5 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.0 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 1.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0001848 complement binding(GO:0001848)
0.0 0.3 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.0 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.0 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.0 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.2 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.2 PID EPO PATHWAY EPO signaling pathway
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.0 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.1 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.4 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression