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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for TP53

Z-value: 2.64

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Transcription factors associated with TP53

Gene Symbol	Gene ID	Gene Info
TP53 Ensembl NCBI GeneCards UniProt	ENSG00000141510.11	tumor protein p53

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_7590385_7590536	TP53	285	0.425615	0.37	3.3e-01	Click!
chr17_7590962_7591207	TP53	228	0.554340	-0.33	3.8e-01	Click!
chr17_7590181_7590354	TP53	478	0.311331	-0.24	5.3e-01	Click!
chr17_7590639_7590790	TP53	31	0.490208	0.01	9.9e-01	Click!

Activity of the TP53 motif across conditions

Conditions sorted by the z-value of the TP53 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr21_36077113_36077512	1.53	CLIC6	chloride intracellular channel 6	35624	0.17
chr16_67213072_67213223	1.52	KIAA0895L	KIAA0895-like	818	0.33
chr10_105545774_105545925	1.51	SH3PXD2A	SH3 and PX domains 2A	15206	0.22
chr12_48157693_48157979	1.41	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3	4975	0.15
chr7_72439829_72440092	1.33	TRIM74	tripartite motif containing 74	37	0.95
chr11_57136881_57137176	1.25	ENSG00000266018	.	9832	0.09
chr4_1760251_1760414	1.22	TACC3	transforming, acidic coiled-coil containing protein 3	30201	0.12
chr21_44913772_44914270	1.22	SIK1	salt-inducible kinase 1	67013	0.12
chr9_80655707_80655858	1.15	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	9408	0.31
chr7_2019784_2019935	1.14	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	567	0.84
chr20_35436907_35437058	1.13	SOGA1	suppressor of glucose, autophagy associated 1	7702	0.17
chr16_70715866_70716017	1.12	MTSS1L	metastasis suppressor 1-like	2013	0.25
chr13_109833240_109833391	1.07	MYO16-AS1	MYO16 antisense RNA 1	20516	0.27
chr15_86006680_86006837	1.06	ENSG00000251891	.	73643	0.09
chr2_217343224_217343375	1.05	AC098820.4		8620	0.16
chr12_13325630_13325838	1.05	EMP1	epithelial membrane protein 1	23916	0.21
chr22_31479008_31479415	1.05	RP3-412A9.16		340	0.68
chr21_43182440_43182683	1.05	RIPK4	receptor-interacting serine-threonine kinase 4	3557	0.23
chr10_30676143_30676294	1.05	ENSG00000239625	.	20971	0.15
chr18_8757570_8757721	1.03	SOGA2	SOGA family member 2	32027	0.14
chr17_77023308_77023681	1.02	C1QTNF1-AS1	C1QTNF1 antisense RNA 1	189	0.91
chr9_130297629_130297780	1.01	FAM129B	family with sequence similarity 129, member B	33663	0.12
chr5_139727515_139728049	1.00	HBEGF	heparin-binding EGF-like growth factor	1566	0.26
chr21_32709213_32709364	0.99	TIAM1	T-cell lymphoma invasion and metastasis 1	7306	0.31
chr20_56888368_56888559	0.99	RAB22A	RAB22A, member RAS oncogene family	3711	0.23
chr3_58038520_58038686	0.97	FLNB	filamin B, beta	25453	0.22
chr8_144576644_144577036	0.96	ZC3H3	zinc finger CCCH-type containing 3	13170	0.1
chr1_205462396_205462547	0.95	CDK18	cyclin-dependent kinase 18	11252	0.17
chr10_105211829_105211980	0.94	CALHM2	calcium homeostasis modulator 2	171	0.82
chr16_75130170_75130321	0.94	ZNRF1	zinc and ring finger 1, E3 ubiquitin protein ligase	8437	0.16
chr12_680528_680679	0.94	RP5-1154L15.2		15049	0.13
chr11_13162605_13162756	0.94	ARNTL	aryl hydrocarbon receptor nuclear translocator-like	135519	0.05
chr19_30159682_30159919	0.93	PLEKHF1	pleckstrin homology domain containing, family F (with FYVE domain) member 1	2019	0.38
chr12_133069275_133069467	0.92	FBRSL1	fibrosin-like 1	2214	0.33
chr20_61196938_61197089	0.92	ENSG00000207764	.	34894	0.1
chr1_11799753_11799904	0.91	AGTRAP	angiotensin II receptor-associated protein	3596	0.15
chr2_1712344_1712495	0.91	PXDN	peroxidasin homolog (Drosophila)	16077	0.26
chr1_223905542_223905721	0.91	CAPN2	calpain 2, (m/II) large subunit	5597	0.23
chr8_124564532_124564683	0.90	FBXO32	F-box protein 32	11161	0.19
chr18_21078643_21078822	0.90	C18orf8	chromosome 18 open reading frame 8	4741	0.19
chr1_184923244_184923895	0.89	FAM129A	family with sequence similarity 129, member A	20113	0.22
chr22_20939877_20940028	0.89	MED15	mediator complex subunit 15	34375	0.11
chr17_73690836_73691014	0.89	SAP30BP	SAP30 binding protein	2299	0.16
chr12_26379598_26379817	0.88	SSPN	sarcospan	31101	0.17
chr13_114540098_114540530	0.87	GAS6	growth arrest-specific 6	1297	0.5
chr20_30149421_30149640	0.87	HM13-IT1	HM13 intronic transcript 1 (non-protein coding)	1439	0.29
chr1_155295266_155295417	0.87	RUSC1	RUN and SH3 domain containing 1	973	0.28
chr11_2405103_2405254	0.86	CD81	CD81 molecule	702	0.53
chr7_151385205_151385463	0.86	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	48015	0.15
chr12_53260991_53261144	0.86	KRT78	keratin 78	18191	0.12
chr15_69306681_69306832	0.85	NOX5	NADPH oxidase, EF-hand calcium binding domain 5	278	0.93
chr8_96237601_96237983	0.85	C8orf37	chromosome 8 open reading frame 37	43637	0.17
chr9_110011565_110011716	0.85	RAD23B	RAD23 homolog B (S. cerevisiae)	33778	0.23
chr15_94779023_94779174	0.85	MCTP2	multiple C2 domains, transmembrane 2	4331	0.37
chr6_1637910_1638061	0.84	FOXC1	forkhead box C1	27304	0.25
chr7_48676082_48676233	0.83	ABCA13	ATP-binding cassette, sub-family A (ABC1), member 13	128689	0.06
chr6_159273798_159273988	0.83	C6orf99	chromosome 6 open reading frame 99	17078	0.17
chr22_43523288_43523514	0.83	MCAT	malonyl CoA:ACP acyltransferase (mitochondrial)	15569	0.13
chr9_127336792_127336943	0.83	NR6A1	nuclear receptor subfamily 6, group A, member 1	21220	0.16
chr2_238774569_238774720	0.82	ENSG00000263723	.	3903	0.23
chr9_137258561_137258821	0.82	ENSG00000263897	.	12566	0.24
chr22_46446134_46446285	0.82	RP6-109B7.5		2764	0.14
chr22_47127444_47127688	0.82	CERK	ceramide kinase	6538	0.2
chr19_47134249_47134400	0.81	GNG8	guanine nucleotide binding protein (G protein), gamma 8	3618	0.11
chr3_157155017_157155291	0.81	PTX3	pentraxin 3, long	576	0.82
chr6_41734575_41734726	0.81	FRS3	fibroblast growth factor receptor substrate 3	11269	0.1
chr3_182880353_182880504	0.81	LAMP3	lysosomal-associated membrane protein 3	242	0.94
chr6_170541741_170541892	0.80	RP5-1086L22.1		29841	0.17
chr2_242843726_242843877	0.80	AC131097.4	Protein LOC285095	901	0.5
chr19_8017646_8018209	0.79	CTD-3193O13.14		6080	0.08
chr5_169371262_169371413	0.79	FAM196B	family with sequence similarity 196, member B	36407	0.2
chr11_44904177_44904328	0.79	TSPAN18	tetraspanin 18	23098	0.24
chr17_46103975_46104168	0.79	COPZ2	coatomer protein complex, subunit zeta 2	7167	0.09
chr15_41912974_41913725	0.78	MGA	MGA, MAX dimerization protein	385	0.85
chr10_103330594_103330745	0.78	DPCD	deleted in primary ciliary dyskinesia homolog (mouse)	263	0.91
chr21_42665164_42665315	0.78	FAM3B	family with sequence similarity 3, member B	23422	0.19
chr21_39875635_39875873	0.78	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog	5347	0.34
chr15_101712297_101712506	0.78	CHSY1	chondroitin sulfate synthase 1	79736	0.08
chr7_131750165_131750462	0.77	ENSG00000252849	.	149232	0.04
chr6_164171668_164171819	0.77	ENSG00000266128	.	89850	0.1
chr6_43760801_43760952	0.77	VEGFA	vascular endothelial growth factor A	18786	0.17
chr14_91125409_91125577	0.77	TTC7B	tetratricopeptide repeat domain 7B	14941	0.16
chr5_32018427_32018625	0.77	ENSG00000266243	.	82261	0.08
chr22_50194959_50195110	0.76	BRD1	bromodomain containing 1	21819	0.18
chr18_46375030_46375181	0.76	RP11-484L8.1		13964	0.26
chr9_137222033_137222297	0.76	RXRA	retinoid X receptor, alpha	3739	0.3
chr17_42426285_42426667	0.76	GRN	granulin	1431	0.24
chr17_27223921_27224072	0.75	FLOT2	flotillin 2	674	0.34
chr9_95895272_95895516	0.75	NINJ1	ninjurin 1	1176	0.46
chr9_129884317_129884468	0.75	ANGPTL2	angiopoietin-like 2	521	0.84
chr2_43332849_43333164	0.75	ENSG00000207087	.	14374	0.28
chr4_7043707_7043922	0.75	TADA2B	transcriptional adaptor 2B	188	0.85
chr5_164649107_164649258	0.75	CTC-340A15.2		248688	0.02
chr1_16007587_16007940	0.74	PLEKHM2	pleckstrin homology domain containing, family M (with RUN domain) member 2	3064	0.14
chr14_23316221_23316458	0.74	ENSG00000212335	.	5598	0.09
chr12_112196283_112196534	0.74	RP11-162P23.2		4714	0.2
chr3_11605975_11606126	0.74	VGLL4	vestigial like 4 (Drosophila)	4348	0.27
chr9_129263345_129263597	0.74	ENSG00000221768	.	29799	0.17
chr4_184276464_184276615	0.74	ENSG00000238596	.	26088	0.12
chr8_141112972_141113273	0.74	C8orf17	chromosome 8 open reading frame 17	169706	0.04
chr5_148532192_148532343	0.74	ABLIM3	actin binding LIM protein family, member 3	10657	0.19
chr20_1822229_1822380	0.73	SIRPA	signal-regulatory protein alpha	52850	0.14
chr1_39583247_39583398	0.73	ENSG00000206654	.	3393	0.22
chr17_45711384_45711535	0.73	RP11-580I16.2		2457	0.21
chr15_75965340_75965508	0.73	CTD-2026K11.1		3144	0.13
chr22_38290809_38291107	0.73	ENSG00000207227	.	3604	0.12
chr3_78968730_78968881	0.73	ENSG00000240964	.	18637	0.29
chr19_2041628_2041930	0.72	MKNK2	MAP kinase interacting serine/threonine kinase 2	302	0.81
chr6_150167412_150167563	0.72	RP11-350J20.12		6111	0.13
chr20_48598530_48598683	0.72	SNAI1	snail family zinc finger 1	930	0.51
chr17_73696089_73696240	0.72	SAP30BP	SAP30 binding protein	7538	0.1
chr6_11236951_11237401	0.72	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	4261	0.29
chr15_75092257_75092507	0.72	CSK	c-src tyrosine kinase	2127	0.19
chr1_8255073_8255224	0.72	ENSG00000200975	.	11509	0.23
chr4_1772588_1772739	0.71	FGFR3	fibroblast growth factor receptor 3	22371	0.14
chr19_35609616_35609767	0.71	FXYD3	FXYD domain containing ion transport regulator 3	257	0.83
chr2_73338202_73338410	0.71	RAB11FIP5	RAB11 family interacting protein 5 (class I)	1840	0.27
chr2_235334574_235334725	0.71	ARL4C	ADP-ribosylation factor-like 4C	70595	0.14
chr7_75024790_75024951	0.71	TRIM73	tripartite motif containing 73	33	0.81
chr3_49841571_49842107	0.71	FAM212A	family with sequence similarity 212, member A	1152	0.26
chr4_157692638_157692789	0.70	RP11-154F14.2		69798	0.11
chr1_230222948_230223099	0.70	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	20005	0.23
chr10_73759545_73759696	0.70	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	35497	0.18
chr3_171510455_171510606	0.70	PP13439		17184	0.19
chr19_4009920_4010213	0.70	PIAS4	protein inhibitor of activated STAT, 4	2422	0.17
chr3_128214441_128214592	0.70	GATA2	GATA binding protein 2	2488	0.24
chr12_707544_707762	0.69	RP5-1154L15.1		7854	0.14
chr9_126860561_126860712	0.69	RP11-85O21.5		65833	0.1
chr1_27152765_27152920	0.69	ZDHHC18	zinc finger, DHHC-type containing 18	359	0.79
chr6_34122364_34122705	0.69	GRM4	glutamate receptor, metabotropic 4	865	0.67
chr7_44224907_44225058	0.69	GCK	glucokinase (hexokinase 4)	3604	0.16
chr1_26198087_26198275	0.69	PAQR7	progestin and adipoQ receptor family member VII	437	0.67
chr2_43161154_43161373	0.69	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	141531	0.04
chr12_133010155_133010306	0.69	MUC8	mucin 8	40496	0.15
chr15_99240331_99240482	0.69	IGF1R	insulin-like growth factor 1 receptor	10654	0.25
chr6_44193791_44194154	0.69	SLC29A1	solute carrier family 29 (equilibrative nucleoside transporter), member 1	904	0.45
chr19_45943533_45943745	0.68	ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)	10344	0.11
chr8_101524438_101524589	0.68	KB-1615E4.3		19757	0.15
chr2_233186649_233186800	0.68	DIS3L2	DIS3 mitotic control homolog (S. cerevisiae)-like 2	11929	0.18
chr10_33603519_33603765	0.68	NRP1	neuropilin 1	19668	0.22
chr1_113246367_113246660	0.68	RHOC	ras homolog family member C	1030	0.35
chr17_38242408_38242559	0.68	THRA	thyroid hormone receptor, alpha	14139	0.11
chrX_17054594_17054895	0.68	ENSG00000201467	.	7890	0.26
chr8_27141267_27141435	0.68	TRIM35	tripartite motif containing 35	10301	0.19
chr9_135993294_135993494	0.67	RALGDS	ral guanine nucleotide dissociation stimulator	3169	0.18
chr1_21584722_21584899	0.67	RP3-329E20.2		7765	0.19
chr17_80393335_80393486	0.67	HEXDC	hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing	1195	0.27
chr12_52889840_52889991	0.67	KRT6A	keratin 6A	2874	0.15
chr4_184016212_184016363	0.67	WWC2	WW and C2 domain containing 2	4159	0.28
chr22_46408978_46409377	0.67	WNT7B	wingless-type MMTV integration site family, member 7B	36168	0.09
chr6_90699562_90699713	0.67	ENSG00000222078	.	11588	0.2
chr11_827569_827736	0.66	EFCAB4A	EF-hand calcium binding domain 4A	67	0.91
chr7_105699016_105699167	0.66	SYPL1	synaptophysin-like 1	39217	0.18
chr1_3470123_3470274	0.66	ENSG00000207776	.	7156	0.18
chr3_172394693_172395213	0.66	ENSG00000264711	.	5524	0.18
chr20_3075913_3076064	0.66	ENSG00000263905	.	1127	0.36
chr18_74776671_74776950	0.66	MBP	myelin basic protein	40407	0.19
chr2_43164380_43164569	0.66	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	144742	0.04
chr1_181002368_181002929	0.65	MR1	major histocompatibility complex, class I-related	419	0.83
chr22_19510729_19510972	0.65	CLDN5	claudin 5	2056	0.26
chr5_57757985_57758173	0.65	PLK2	polo-like kinase 2	1992	0.37
chr1_24689814_24689965	0.65	STPG1	sperm-tail PG-rich repeat containing 1	16424	0.16
chr19_39343355_39343519	0.65	HNRNPL	heterogeneous nuclear ribonucleoprotein L	459	0.6
chr5_127874936_127875155	0.65	FBN2	fibrillin 2	1129	0.44
chr15_78287465_78287616	0.64	RP11-114H24.6		1793	0.25
chr7_17573125_17573276	0.64	ENSG00000199473	.	160250	0.04
chr10_124251115_124251760	0.64	HTRA1	HtrA serine peptidase 1	14770	0.19
chr2_60114623_60115116	0.64	ENSG00000252726	.	192972	0.03
chr13_36991056_36991207	0.64	CCNA1	cyclin A1	14836	0.19
chr13_51163135_51163351	0.64	DLEU7-AS1	DLEU7 antisense RNA 1	218749	0.02
chr14_77466848_77467305	0.64	IRF2BPL	interferon regulatory factor 2 binding protein-like	27958	0.16
chr10_81029619_81029967	0.64	ZMIZ1	zinc finger, MIZ-type containing 1	36182	0.19
chr14_100906897_100907135	0.64	RP11-362L22.1		33774	0.1
chr15_90754517_90755171	0.63	SEMA4B	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	10076	0.12
chr13_114504859_114505144	0.63	GAS6-AS1	GAS6 antisense RNA 1	13602	0.2
chr5_32027583_32027753	0.63	ENSG00000266243	.	91403	0.07
chr2_62806762_62807072	0.63	TMEM17	transmembrane protein 17	73441	0.1
chr16_57798443_57798674	0.63	KIFC3	kinesin family member C3	257	0.89
chr1_33226657_33226808	0.63	KIAA1522	KIAA1522	4503	0.18
chr12_124993315_124993466	0.63	NCOR2	nuclear receptor corepressor 2	9450	0.31
chr9_130484503_130484654	0.63	PTRH1	peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)	2574	0.15
chr9_139000327_139000606	0.62	C9orf69	chromosome 9 open reading frame 69	9654	0.19
chr19_1181543_1181837	0.62	SBNO2	strawberry notch homolog 2 (Drosophila)	7408	0.12
chr16_75278877_75279029	0.62	BCAR1	breast cancer anti-estrogen resistance 1	2353	0.21
chr15_79048558_79048709	0.62	RP11-160C18.4		3177	0.23
chr11_75063180_75063331	0.62	ARRB1	arrestin, beta 1	382	0.81
chr6_35463588_35463761	0.62	TEAD3	TEA domain family member 3	1053	0.49
chr1_218338811_218338962	0.62	ENSG00000201493	.	35749	0.22
chr6_138059271_138059422	0.62	ENSG00000216097	.	21261	0.21
chr3_196705880_196706031	0.62	PIGZ	phosphatidylinositol glycan anchor biosynthesis, class Z	10213	0.14
chr2_134907045_134907307	0.61	ENSG00000263813	.	22480	0.21
chr5_172159959_172160110	0.61	RP11-779O18.1		25195	0.12
chr6_119417895_119418107	0.61	FAM184A	family with sequence similarity 184, member A	17657	0.19
chr8_143897122_143897273	0.61	GML	glycosylphosphatidylinositol anchored molecule like	18466	0.1
chr5_176795562_176795713	0.61	RGS14	regulator of G-protein signaling 14	1693	0.2
chr6_44035221_44035381	0.61	RP5-1120P11.1		7088	0.18
chr7_55132507_55132658	0.61	EGFR	epidermal growth factor receptor	44834	0.19
chr1_12678566_12678717	0.61	DHRS3	dehydrogenase/reductase (SDR family) member 3	904	0.57
chr19_42896339_42896490	0.61	CNFN	cornifelin	1975	0.2
chr2_109935113_109935264	0.61	ENSG00000265965	.	5107	0.34

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.1	GO:0018101	protein citrullination(GO:0018101)
0.2	1.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.2	0.7	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.2	0.8	GO:0000089	mitotic metaphase(GO:0000089)
0.2	0.5	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.2	0.5	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.4	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.1	0.4	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.4	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.4	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	0.7	GO:0001878	response to yeast(GO:0001878)
0.1	0.4	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.5	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.1	GO:0032261	purine nucleotide salvage(GO:0032261)
0.1	0.2	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.1	0.5	GO:0051541	elastin metabolic process(GO:0051541)
0.1	0.6	GO:0045217	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.1	0.4	GO:0090400	stress-induced premature senescence(GO:0090400)
0.1	0.5	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1	0.7	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.3	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.5	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.2	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.3	GO:0008215	spermine metabolic process(GO:0008215)
0.1	0.4	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	0.4	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.1	0.3	GO:0010159	specification of organ position(GO:0010159)
0.1	0.3	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1	0.2	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.3	GO:0003179	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.1	0.3	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1	0.3	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.3	GO:0034629	cellular protein complex localization(GO:0034629)
0.1	0.2	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.3	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.5	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1	0.2	GO:0046881	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1	0.2	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1	0.2	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.1	0.3	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.2	GO:0060433	bronchus development(GO:0060433)
0.1	0.2	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.2	GO:0042637	catagen(GO:0042637)
0.1	0.2	GO:0060510	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.1	0.5	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.1	0.2	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1	0.2	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.2	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.4	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.1	0.2	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.1	0.7	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.1	0.6	GO:0010155	regulation of proton transport(GO:0010155)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.2	GO:0019372	lipoxygenase pathway(GO:0019372)
0.1	0.3	GO:0016246	RNA interference(GO:0016246)
0.1	0.2	GO:0070977	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.1	0.5	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.1	0.1	GO:0090192	regulation of glomerulus development(GO:0090192)
0.1	0.1	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.1	0.2	GO:0021978	telencephalon regionalization(GO:0021978)
0.1	0.6	GO:0034453	microtubule anchoring(GO:0034453)
0.1	0.2	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.4	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.1	0.2	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.2	GO:0070295	renal water absorption(GO:0070295)
0.1	0.6	GO:0010822	positive regulation of mitochondrion organization(GO:0010822) positive regulation of release of cytochrome c from mitochondria(GO:0090200) positive regulation of apoptotic signaling pathway(GO:2001235)
0.1	0.6	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.1	0.1	GO:0071503	response to heparin(GO:0071503)
0.1	0.2	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.1	0.2	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.1	0.1	GO:0072109	glomerular mesangium development(GO:0072109)
0.1	0.1	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.1	0.2	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1	0.1	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
0.1	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.1	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.1	0.2	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.1	0.2	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	0.2	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.2	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.4	GO:0009629	response to gravity(GO:0009629)
0.1	0.3	GO:0051382	kinetochore assembly(GO:0051382)
0.1	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.1	0.2	GO:0009301	snRNA transcription(GO:0009301)
0.1	0.1	GO:0044321	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.1	0.2	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.1	0.1	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.1	0.2	GO:0046471	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.1	0.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.1	0.2	GO:0034650	cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.0	0.0	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.8	GO:0018200	peptidyl-glutamic acid modification(GO:0018200)
0.0	0.2	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.6	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.1	GO:0060346	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.4	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.3	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.8	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.2	GO:0014741	negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.0	0.0	GO:0003057	regulation of the force of heart contraction by chemical signal(GO:0003057)
0.0	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.2	GO:0070141	response to UV-A(GO:0070141)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.2	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.3	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.3	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.3	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.5	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	0.2	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.3	GO:0007143	female meiotic division(GO:0007143)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.5	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0042635	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.3	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.0	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.3	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.0	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.0	0.0	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0	0.2	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.5	GO:0060761	negative regulation of response to cytokine stimulus(GO:0060761)
0.0	0.1	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.2	GO:0090199	negative regulation of mitochondrion organization(GO:0010823) regulation of release of cytochrome c from mitochondria(GO:0090199) negative regulation of release of cytochrome c from mitochondria(GO:0090201) regulation of apoptotic signaling pathway(GO:2001233) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.3	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.3	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.1	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.6	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.6	GO:0006541	glutamine metabolic process(GO:0006541)
0.0	0.1	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:1901722	regulation of cell proliferation involved in kidney development(GO:1901722)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.3	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.1	GO:0019730	antimicrobial humoral response(GO:0019730)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.0	GO:0010821	regulation of mitochondrion organization(GO:0010821)
0.0	0.1	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.2	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.1	GO:0001743	optic placode formation(GO:0001743)
0.0	0.7	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.3	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.2	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0010611	regulation of cardiac muscle hypertrophy(GO:0010611) regulation of muscle hypertrophy(GO:0014743)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.2	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:0060767	epithelial cell proliferation involved in prostate gland development(GO:0060767)
0.0	0.2	GO:0070633	transepithelial transport(GO:0070633)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.2	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.2	GO:0009154	purine ribonucleotide catabolic process(GO:0009154)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.3	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0045605	negative regulation of epidermal cell differentiation(GO:0045605)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	1.1	GO:0006821	chloride transport(GO:0006821)
0.0	0.2	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.4	GO:0048246	macrophage chemotaxis(GO:0048246)
0.0	0.2	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.0	0.1	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.0	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.3	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.1	GO:0035247	peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.0	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.1	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.5	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.0	0.0	GO:0034113	heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.2	GO:0046051	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.1	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.0	0.2	GO:0060612	adipose tissue development(GO:0060612)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.2	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.4	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.0	0.2	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.3	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0048263	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0	0.0	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.1	GO:0071223	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.2	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.0	GO:1902019	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.2	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0071347	cellular response to interleukin-1(GO:0071347)
0.0	0.0	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0034243	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.2	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.6	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.1	GO:0070875	positive regulation of glycogen metabolic process(GO:0070875)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0036303	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	0.4	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.1	GO:0042554	superoxide anion generation(GO:0042554)
0.0	0.0	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.1	GO:0035094	response to nicotine(GO:0035094)
0.0	0.0	GO:0051797	regulation of hair follicle development(GO:0051797)
0.0	0.0	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.1	GO:0046697	decidualization(GO:0046697)
0.0	0.2	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.0	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0060996	dendritic spine development(GO:0060996)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.0	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.0	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.1	GO:1903428	positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.0	GO:0001865	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0014059	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.1	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.9	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0	0.0	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.3	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:1902221	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.2	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.1	GO:0006195	purine nucleotide catabolic process(GO:0006195)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.1	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0045616	regulation of keratinocyte differentiation(GO:0045616)
0.0	0.0	GO:0010889	regulation of sequestering of triglyceride(GO:0010889)
0.0	0.1	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.4	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.2	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.0	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.0	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.2	GO:0009595	detection of biotic stimulus(GO:0009595)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.4	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0045682	regulation of epidermis development(GO:0045682)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.2	GO:0000718	nucleotide-excision repair, DNA damage removal(GO:0000718) DNA excision(GO:0044349)
0.0	0.0	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.0	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.0	GO:0009648	photoperiodism(GO:0009648)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.1	GO:0033574	response to testosterone(GO:0033574)
0.0	0.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.0	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.0	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0072676	lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0	1.7	GO:0006184	obsolete GTP catabolic process(GO:0006184)
0.0	0.0	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.0	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.0	GO:0042982	amyloid precursor protein metabolic process(GO:0042982)
0.0	0.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0009267	cellular response to starvation(GO:0009267)
0.0	0.1	GO:0061647	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:0035338	long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.1	GO:0034130	toll-like receptor 1 signaling pathway(GO:0034130)
0.0	0.2	GO:0001938	positive regulation of endothelial cell proliferation(GO:0001938)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.2	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0015909	long-chain fatty acid transport(GO:0015909)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.0	GO:0031659	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.3	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0006560	proline metabolic process(GO:0006560)
0.0	0.0	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.0	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.0	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.2	GO:0042246	tissue regeneration(GO:0042246)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.0	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.0	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.0	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.4	GO:0031424	keratinization(GO:0031424)
0.0	0.1	GO:0050432	catecholamine secretion(GO:0050432)
0.0	0.0	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.0	GO:0045628	regulation of T-helper 2 cell differentiation(GO:0045628)
0.0	0.1	GO:0006929	substrate-dependent cell migration(GO:0006929)
0.0	0.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.0	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.0	0.4	GO:0007219	Notch signaling pathway(GO:0007219)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0034434	steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0	0.0	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0031498	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0042133	neurotransmitter metabolic process(GO:0042133)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.0	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.0	GO:0010002	cardioblast differentiation(GO:0010002)
0.0	0.3	GO:0090662	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0032449	CBM complex(GO:0032449)
0.1	0.5	GO:0005828	kinetochore microtubule(GO:0005828)
0.1	0.6	GO:0005915	zonula adherens(GO:0005915)
0.1	0.4	GO:0002080	acrosomal membrane(GO:0002080)
0.1	0.7	GO:0002102	podosome(GO:0002102)
0.1	1.0	GO:0030914	STAGA complex(GO:0030914)
0.1	0.6	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	0.3	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.1	0.3	GO:0016600	flotillin complex(GO:0016600)
0.1	0.5	GO:0031143	pseudopodium(GO:0031143)
0.1	0.3	GO:0070552	BRISC complex(GO:0070552)
0.1	0.3	GO:0030061	mitochondrial crista(GO:0030061)
0.1	0.3	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	1.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.1	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.5	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.6	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.6	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.5	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.7	GO:0031201	SNARE complex(GO:0031201)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.4	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	2.8	GO:0045095	keratin filament(GO:0045095)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.8	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0043230	extracellular organelle(GO:0043230)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.7	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	2.5	GO:0005925	focal adhesion(GO:0005925)
0.0	0.2	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	1.5	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.2	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.2	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0030288	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.2	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	1.6	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.4	GO:0005811	lipid particle(GO:0005811)
0.0	1.3	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.4	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0045281	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.0	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.3	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	1.2	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.0	GO:0097526	U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.0	GO:0070069	cytochrome complex(GO:0070069)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.2	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.0	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.0	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	1.5	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	0.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.8	GO:0005643	nuclear pore(GO:0005643)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.6	GO:0000922	spindle pole(GO:0000922)
0.0	0.1	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.4	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.1	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0030175	filopodium(GO:0030175)
0.0	0.4	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	1.3	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.5	GO:0031901	early endosome membrane(GO:0031901)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.0	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.3	1.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.2	1.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.2	0.6	GO:0043515	kinetochore binding(GO:0043515)
0.2	0.6	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.5	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.4	GO:0046848	hydroxyapatite binding(GO:0046848)
0.1	0.5	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.3	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.5	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.3	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.7	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.4	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.3	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.9	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.3	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.2	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1	0.2	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.1	0.3	GO:0032190	acrosin binding(GO:0032190)
0.1	0.2	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	0.5	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.5	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1	0.2	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	0.8	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.2	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.1	0.3	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	0.6	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.2	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1	0.4	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1	0.2	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.1	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.1	0.2	GO:0004104	cholinesterase activity(GO:0004104)
0.1	1.0	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.1	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.3	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.1	0.5	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.1	0.5	GO:0031701	angiotensin receptor binding(GO:0031701)
0.1	0.2	GO:0015254	glycerol channel activity(GO:0015254)
0.1	0.4	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.1	0.3	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.6	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.2	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	0.2	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.6	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.1	0.2	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.1	0.2	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.1	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.2	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1	0.2	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1	0.7	GO:0032393	MHC class I receptor activity(GO:0032393)
0.1	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.3	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.3	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.3	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.4	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.4	GO:0030332	cyclin binding(GO:0030332)
0.0	0.3	GO:0030547	receptor inhibitor activity(GO:0030547)
0.0	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.7	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.2	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.2	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.4	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.9	GO:0051117	ATPase binding(GO:0051117)
0.0	0.2	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.4	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.2	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.4	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.3	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	1.0	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.3	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.2	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.4	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.5	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.5	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0043139	5'-3' DNA helicase activity(GO:0043139)
0.0	0.0	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.4	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.4	GO:0030552	cAMP binding(GO:0030552)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.4	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.2	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.4	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.0	GO:0016019	peptidoglycan receptor activity(GO:0016019)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.3	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.3	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.2	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.3	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.2	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0	0.6	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.2	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0042806	fucose binding(GO:0042806)
0.0	0.0	GO:0015205	nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.2	GO:0003840	gamma-glutamyltransferase activity(GO:0003840)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.0	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.4	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.2	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.3	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.6	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.3	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.3	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.0	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.0	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.3	GO:0008066	glutamate receptor activity(GO:0008066)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.5	GO:0001104	transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.0	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0010853	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.0	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.0	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.7	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0071617	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.1	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.0	0.1	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.1	GO:0080032	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.2	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.0	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.3	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor(GO:0050664)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.0	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.1	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.1	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0001077	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.7	GO:0005496	steroid binding(GO:0005496)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.0	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.4	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.2	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.1	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.6	GO:0019838	growth factor binding(GO:0019838)
0.0	0.0	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0015114	phosphate ion transmembrane transporter activity(GO:0015114)
0.0	2.0	GO:0003924	GTPase activity(GO:0003924)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.0	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.3	GO:0002020	protease binding(GO:0002020)
0.0	0.2	GO:0004623	phospholipase A2 activity(GO:0004623)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.0	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.2	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	0.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	1.3	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.1	1.8	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	1.3	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.4	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.3	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.8	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.0	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.5	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	1.4	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	1.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.4	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.6	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.3	PID FOXO PATHWAY	FoxO family signaling
0.0	0.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	4.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.7	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.5	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.3	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.1	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.5	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.0	0.2	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.0	0.3	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.3	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.4	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.1	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.0	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.4	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.3	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.0	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.9	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	0.9	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	0.6	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	0.7	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	1.4	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.1	0.8	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.6	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.6	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.0	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.7	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.6	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.5	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.0	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	1.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.7	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.0	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.7	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.5	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.6	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.0	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.1	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.2	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.1	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.0	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	1.2	REACTOME MITOTIC G2 G2 M PHASES	Genes involved in Mitotic G2-G2/M phases
0.0	0.4	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.0	REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK	Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.0	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.1	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.0	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.3	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.1	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis

Results for TP53

Z-value: 2.64

Motif logo

Transcription factors associated with TP53

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the TP53 motif across conditions

Conditions sorted by the z-value of the TP53 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of TP53

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: