Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for VAX2_RHOXF2

Z-value: 0.51

Motif logo

logo of logo of

Transcription factors associated with VAX2_RHOXF2

Gene Symbol Gene ID Gene Info
VAX2
ENSG00000116035.2 ventral anterior homeobox 2
RHOXF2
ENSG00000131721.4 Rhox homeobox family member 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chrX_119279296_119279447RHOXF2130960.1664200.723.0e-02Click!
chrX_119314962_119315113RHOXF2225700.171382-0.646.4e-02Click!
chrX_119314020_119314171RHOXF2216280.173157-0.636.8e-02Click!
chrX_119273447_119273598RHOXF2189450.150548-0.627.7e-02Click!
chrX_119290299_119290450RHOXF220930.309387-0.206.0e-01Click!
chr2_71114393_71114674VAX2131870.1241270.732.7e-02Click!
chr2_71124315_71124466VAX233300.1629540.617.9e-02Click!
chr2_71128195_71128714VAX27340.5482450.609.0e-02Click!
chr2_71115100_71115342VAX2124990.1247840.551.3e-01Click!
chr2_71116829_71116980VAX2108160.1264700.531.4e-01Click!

Activity of the VAX2_RHOXF2 motif across conditions

Conditions sorted by the z-value of the VAX2_RHOXF2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_126941263_126941691 0.38 ENSG00000206695
 .
 28282
 0.26
chr15_52802125_52802276 0.35 MYO5A
 myosin VA (heavy chain 12, myoxin)
 18838
 0.2
chr14_98641364_98641616 0.33 ENSG00000222066
 .
 156597
 0.04
chr17_47825562_47826034 0.32 FAM117A
 family with sequence similarity 117, member A
 15695
 0.14
chr14_61812224_61812375 0.30 PRKCH
 protein kinase C, eta
 1257
 0.5
chrX_11784442_11784722 0.29 MSL3
 male-specific lethal 3 homolog (Drosophila)
 6835
 0.32
chr5_140934914_140935065 0.29 CTD-2024I7.13
2889
 0.17
chr10_48508940_48509161 0.28 GDF10
 growth differentiation factor 10
 70074
 0.1
chr1_169571123_169571274 0.28 F5
 coagulation factor V (proaccelerin, labile factor)
 15372
 0.19
chr19_47948776_47948927 0.27 MEIS3
 Meis homeobox 3
 26071
 0.11
chr14_98605614_98605900 0.27 C14orf64
 chromosome 14 open reading frame 64
 161296
 0.04
chr4_153000457_153000739 0.27 ENSG00000253077
 .
 107833
 0.07
chr3_121990121_121990409 0.27 ENSG00000221474
 .
 10435
 0.16
chr11_9416407_9416558 0.27 IPO7
 importin 7
 10282
 0.16
chr10_22899839_22899998 0.26 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
 19276
 0.27
chr17_14101706_14102107 0.26 AC005224.2
11899
 0.2
chr15_60850340_60850622 0.26 CTD-2501E16.2
28309
 0.16
chr3_56963223_56963374 0.26 ARHGEF3-AS1
 ARHGEF3 antisense RNA 1
 10770
 0.22
chr2_43388712_43388910 0.26 ZFP36L2
 ZFP36 ring finger protein-like 2
 64937
 0.11
chr6_158677695_158677913 0.25 TULP4
 tubby like protein 4
 55888
 0.12
chr5_146138797_146138948 0.25 ENSG00000265875
 .
 24474
 0.23
chr1_175157741_175158025 0.25 KIAA0040
 KIAA0040
 4007
 0.31
chr2_122458404_122458555 0.24 ENSG00000238341
 .
 5154
 0.2
chr15_85302679_85303048 0.24 RP11-7M10.2
6510
 0.15
chr6_13686993_13687323 0.24 RANBP9
 RAN binding protein 9
 22
 0.98
chr16_68502814_68502979 0.24 ENSG00000199263
 .
 5671
 0.17
chr2_106545238_106545692 0.24 AC009505.2
71832
 0.11
chr17_71720142_71720293 0.24 SDK2
 sidekick cell adhesion molecule 2
 79989
 0.1
chr14_91858695_91858977 0.24 CCDC88C
 coiled-coil domain containing 88C
 24854
 0.2
chr15_89170331_89170558 0.23 AEN
 apoptosis enhancing nuclease
 5843
 0.16
chr11_30346022_30346188 0.23 ARL14EP
 ADP-ribosylation factor-like 14 effector protein
 1507
 0.54
chr17_14094666_14094817 0.23 ENSG00000252305
 .
 14293
 0.19
chr4_78749172_78749323 0.23 CNOT6L
 CCR4-NOT transcription complex, subunit 6-like
 8478
 0.26
chr2_148056205_148056470 0.23 ENSG00000238860
 .
 25202
 0.25
chr6_2893026_2893177 0.23 SERPINB9
 serpin peptidase inhibitor, clade B (ovalbumin), member 9
 10413
 0.18
chr15_61011663_61011814 0.23 ENSG00000212625
 .
 17230
 0.2
chr9_34662044_34662195 0.22 CCL27
 chemokine (C-C motif) ligand 27
 570
 0.53
chr13_21121097_21121248 0.22 IFT88
 intraflagellar transport 88 homolog (Chlamydomonas)
 19413
 0.18
chr11_117877070_117877221 0.22 IL10RA
 interleukin 10 receptor, alpha
 20036
 0.16
chr10_64515756_64515907 0.22 ADO
 2-aminoethanethiol (cysteamine) dioxygenase
 48685
 0.13
chr18_32701325_32701476 0.22 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
 79786
 0.1
chr5_75600048_75600202 0.22 RP11-466P24.6
7162
 0.3
chr8_29412378_29412770 0.22 RP4-676L2.1
201887
 0.02
chrX_118813796_118814051 0.21 SEPT6
 septin 6
 12869
 0.17
chr1_27156953_27157104 0.21 ZDHHC18
 zinc finger, DHHC-type containing 18
 1467
 0.28
chr14_99680375_99680629 0.21 AL109767.1
48783
 0.14
chr12_66712818_66712969 0.21 HELB
 helicase (DNA) B
 16568
 0.16
chr6_11357904_11358055 0.21 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 24553
 0.24
chr17_65449492_65449678 0.21 ENSG00000244610
 .
 3821
 0.17
chr11_65869578_65869729 0.21 PACS1
 phosphofurin acidic cluster sorting protein 1
 1419
 0.28
chr1_235439552_235439703 0.21 GGPS1
 geranylgeranyl diphosphate synthase 1
 51038
 0.11
chr5_156969848_156970007 0.21 AC106801.1
23045
 0.14
chr6_159338511_159338747 0.21 ENSG00000223191
 .
 8974
 0.2
chr3_3204987_3205138 0.21 RP11-97C16.1
10436
 0.17
chr3_112193935_112194086 0.21 BTLA
 B and T lymphocyte associated
 24195
 0.21
chr5_82767930_82768081 0.21 VCAN
 versican
 261
 0.95
chr9_71643128_71643290 0.21 FXN
 frataxin
 6966
 0.23
chr20_43628950_43629101 0.21 ENSG00000252021
 .
 3964
 0.19
chr5_56129477_56129628 0.21 MAP3K1
 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
 18151
 0.15
chr5_122851393_122851548 0.21 CSNK1G3
 casein kinase 1, gamma 3
 3516
 0.28
chr11_44752503_44752654 0.21 TSPAN18
 tetraspanin 18
 3854
 0.33
chr13_48886676_48886893 0.21 RB1
 retinoblastoma 1
 8873
 0.27
chr3_16356148_16356299 0.20 RP11-415F23.2
277
 0.9
chr6_108114469_108114620 0.20 SCML4
 sex comb on midleg-like 4 (Drosophila)
 21089
 0.25
chr8_21823445_21823677 0.20 XPO7
 exportin 7
 188
 0.94
chr7_21471999_21472183 0.20 SP4
 Sp4 transcription factor
 4430
 0.22
chr5_75688534_75688866 0.20 IQGAP2
 IQ motif containing GTPase activating protein 2
 10374
 0.28
chr16_74573386_74573537 0.20 GLG1
 golgi glycoprotein 1
 23762
 0.19
chr14_68808631_68808789 0.20 RAD51B
 RAD51 paralog B
 69517
 0.12
chr10_102996848_102997121 0.20 LBX1-AS1
 LBX1 antisense RNA 1 (head to head)
 711
 0.61
chr5_118654433_118654664 0.20 ENSG00000243333
 .
 12222
 0.19
chr1_167435126_167435452 0.20 RP11-104L21.2
7391
 0.22
chr3_184274253_184274404 0.20 EIF2B5-AS1
 EIF2B5 antisense RNA 1
 378
 0.86
chr19_36000408_36000843 0.20 DMKN
 dermokine
 488
 0.65
chr2_109603249_109603400 0.20 EDAR
 ectodysplasin A receptor
 2401
 0.41
chr5_130638723_130638874 0.20 CDC42SE2
 CDC42 small effector 2
 39005
 0.21
chr11_128167606_128167864 0.20 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 207554
 0.02
chr1_115041886_115042037 0.20 ENSG00000201114
 .
 8615
 0.22
chr1_66712472_66712670 0.19 PDE4B
 phosphodiesterase 4B, cAMP-specific
 10759
 0.3
chr4_78777778_78777929 0.19 MRPL1
 mitochondrial ribosomal protein L1
 5821
 0.28
chr2_205942725_205942950 0.19 PARD3B
 par-3 family cell polarity regulator beta
 532114
 0.0
chr7_128880488_128880639 0.19 AHCYL2
 adenosylhomocysteinase-like 2
 15672
 0.16
chr5_112359168_112359319 0.19 DCP2
 decapping mRNA 2
 46764
 0.15
chrX_20048047_20048247 0.19 ENSG00000264566
 .
 12842
 0.17
chr6_117804732_117805043 0.19 DCBLD1
 discoidin, CUB and LCCL domain containing 1
 1062
 0.49
chr4_123556022_123556173 0.19 IL21
 interleukin 21
 13873
 0.21
chr12_838464_838718 0.19 WNK1
 WNK lysine deficient protein kinase 1
 23168
 0.18
chr5_156636522_156636760 0.19 CTB-4E7.1
14749
 0.12
chr1_167615092_167615243 0.19 RP3-455J7.4
15256
 0.19
chr1_100844302_100844453 0.19 ENSG00000216067
 .
 46
 0.98
chr7_6522910_6523061 0.19 FLJ20306
 CDNA FLJ20306 fis, clone HEP06881; Putative uncharacterized protein FLJ20306; Uncharacterized protein
 63
 0.89
chr15_60865631_60865913 0.19 RORA
 RAR-related orphan receptor A
 18968
 0.19
chr3_108566035_108566186 0.19 TRAT1
 T cell receptor associated transmembrane adaptor 1
 24491
 0.23
chr16_74620197_74620348 0.19 GLG1
 golgi glycoprotein 1
 20720
 0.2
chr6_647016_647167 0.19 HUS1B
 HUS1 checkpoint homolog b (S. pombe)
 9872
 0.27
chr1_29490695_29490846 0.19 RP11-242O24.5
11769
 0.16
chrX_39170629_39170782 0.19 ENSG00000207122
 .
 230167
 0.02
chr3_112040032_112040183 0.19 CD200
 CD200 molecule
 11087
 0.23
chr7_12254768_12254919 0.19 TMEM106B
 transmembrane protein 106B
 3894
 0.37
chr12_10282940_10283100 0.19 CLEC7A
 C-type lectin domain family 7, member A
 164
 0.93
chr17_33863325_33863476 0.19 SLFN12L
 schlafen family member 12-like
 1480
 0.27
chr6_157109556_157109748 0.19 RP11-230C9.3
8063
 0.2
chr20_34234716_34234867 0.19 ENSG00000252549
 .
 561
 0.6
chr5_171611435_171611646 0.19 STK10
 serine/threonine kinase 10
 3850
 0.23
chr2_15318659_15318819 0.18 NBAS
 neuroblastoma amplified sequence
 11782
 0.32
chr2_166185054_166185205 0.18 SCN2A
 sodium channel, voltage-gated, type II, alpha subunit
 32846
 0.22
chr12_12775741_12775989 0.18 CREBL2
 cAMP responsive element binding protein-like 2
 11039
 0.2
chr16_4114751_4115046 0.18 RP11-462G12.4
32885
 0.16
chr9_92032244_92032395 0.18 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 1429
 0.51
chr10_4121743_4121894 0.18 KLF6
 Kruppel-like factor 6
 294345
 0.01
chr17_33348954_33349130 0.18 RFFL
 ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
 612
 0.63
chr6_156720023_156720174 0.18 ENSG00000212295
 .
 20214
 0.3
chr17_40700754_40700905 0.18 HSD17B1
 hydroxysteroid (17-beta) dehydrogenase 1
 403
 0.66
chr18_60873699_60873977 0.18 ENSG00000238988
 .
 11940
 0.23
chr3_184325833_184325984 0.18 EPHB3
 EPH receptor B3
 46336
 0.13
chr6_119226723_119226983 0.18 ASF1A
 anti-silencing function 1A histone chaperone
 11469
 0.19
chr14_52381180_52381331 0.18 GNG2
 guanine nucleotide binding protein (G protein), gamma 2
 1425
 0.37
chr6_122733810_122733961 0.18 HSF2
 heat shock transcription factor 2
 9416
 0.25
chr2_106522886_106523037 0.18 AC009505.2
49328
 0.16
chr6_112020418_112020739 0.18 FYN
 FYN oncogene related to SRC, FGR, YES
 20687
 0.21
chr6_135414750_135415028 0.18 HBS1L
 HBS1-like (S. cerevisiae)
 9305
 0.22
chr10_8130727_8131157 0.17 GATA3
 GATA binding protein 3
 34173
 0.24
chr14_53258584_53258855 0.17 GNPNAT1
 glucosamine-phosphate N-acetyltransferase 1
 333
 0.86
chr20_57722289_57722440 0.17 ZNF831
 zinc finger protein 831
 43711
 0.15
chr17_63031973_63032289 0.17 RP11-583F2.5
15896
 0.16
chr3_42258092_42258243 0.17 ENSG00000222872
 .
 5165
 0.23
chr14_92973076_92973375 0.17 RIN3
 Ras and Rab interactor 3
 6893
 0.29
chr4_20916404_20916555 0.17 KCNIP4
 Kv channel interacting protein 4
 69153
 0.13
chr3_32998308_32998459 0.17 CCR4
 chemokine (C-C motif) receptor 4
 5317
 0.28
chr16_11346729_11346935 0.17 SOCS1
 suppressor of cytokine signaling 1
 3204
 0.12
chr10_16877098_16877261 0.17 RSU1
 Ras suppressor protein 1
 17652
 0.26
chr2_30557961_30558163 0.17 ENSG00000221377
 .
 97252
 0.07
chr5_49991075_49991374 0.17 PARP8
 poly (ADP-ribose) polymerase family, member 8
 27833
 0.27
chrY_7194717_7195015 0.17 ENSG00000252633
 .
 2230
 0.31
chr7_25004547_25004698 0.17 OSBPL3
 oxysterol binding protein-like 3
 15138
 0.26
chr5_64919668_64919819 0.17 TRIM23
 tripartite motif containing 23
 380
 0.59
chr15_93372987_93373270 0.17 FAM174B
 family with sequence similarity 174, member B
 20100
 0.15
chr10_30991700_30991887 0.17 SVILP1
 supervillin pseudogene 1
 6943
 0.27
chr5_114715684_114715835 0.17 CCDC112
 coiled-coil domain containing 112
 83231
 0.09
chr4_109022417_109022568 0.17 LEF1
 lymphoid enhancer-binding factor 1
 64965
 0.11
chr2_158768231_158768382 0.17 ENSG00000251980
 .
 978
 0.56
chr11_65107055_65107206 0.17 DPF2
 D4, zinc and double PHD fingers family 2
 5792
 0.12
chr14_22535112_22535263 0.17 ENSG00000238634
 .
 75700
 0.11
chr3_14467854_14468179 0.17 SLC6A6
 solute carrier family 6 (neurotransmitter transporter), member 6
 6162
 0.25
chr13_42969980_42970150 0.17 AKAP11
 A kinase (PRKA) anchor protein 11
 123776
 0.06
chr2_235395214_235395372 0.17 ARL4C
 ADP-ribosylation factor-like 4C
 9951
 0.32
chr7_138768806_138768957 0.17 ZC3HAV1
 zinc finger CCCH-type, antiviral 1
 4868
 0.24
chr5_55443907_55444286 0.17 ENSG00000223003
 .
 1423
 0.42
chr8_121714189_121714356 0.17 RP11-713M15.1
59221
 0.14
chr21_43810236_43810387 0.17 TMPRSS3
 transmembrane protease, serine 3
 5741
 0.14
chr10_6087007_6087203 0.17 IL2RA
 interleukin 2 receptor, alpha
 17148
 0.13
chr22_27066729_27066953 0.17 CRYBA4
 crystallin, beta A4
 48913
 0.13
chr16_3865090_3865241 0.16 CREBBP
 CREB binding protein
 34297
 0.17
chr5_118678786_118679078 0.16 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
 10062
 0.21
chr8_81976580_81976731 0.16 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 47648
 0.18
chr22_40340974_40341233 0.16 GRAP2
 GRB2-related adaptor protein 2
 1718
 0.34
chr6_133057981_133058132 0.16 VNN3
 vanin 3
 2152
 0.22
chr2_63287841_63287992 0.16 OTX1
 orthodenticle homeobox 1
 9979
 0.23
chr10_102989164_102989315 0.16 LBX1-AS1
 LBX1 antisense RNA 1 (head to head)
 112
 0.75
chr17_8311463_8311614 0.16 NDEL1
 nudE neurodevelopment protein 1-like 1
 4911
 0.12
chr6_35649971_35650157 0.16 FKBP5
 FK506 binding protein 5
 6628
 0.14
chr1_155910079_155910230 0.16 RXFP4
 relaxin/insulin-like family peptide receptor 4
 1326
 0.24
chr11_35020496_35020647 0.16 PDHX
 pyruvate dehydrogenase complex, component X
 21240
 0.2
chr8_126930029_126930180 0.16 ENSG00000206695
 .
 16909
 0.3
chr3_53072608_53072759 0.16 SFMBT1
 Scm-like with four mbt domains 1
 6598
 0.19
chr12_58147924_58148156 0.16 MARCH9
 membrane-associated ring finger (C3HC4) 9
 841
 0.29
chr18_67554931_67555082 0.16 CD226
 CD226 molecule
 59649
 0.15
chr4_57687212_57687509 0.16 SPINK2
 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
 500
 0.74
chr8_27223358_27224128 0.16 PTK2B
 protein tyrosine kinase 2 beta
 14425
 0.22
chr17_73374792_73374943 0.16 RP11-16C1.2
5050
 0.11
chr6_149404447_149404642 0.16 RP11-162J8.3
50835
 0.15
chr19_12442701_12443014 0.16 ZNF563
 zinc finger protein 563
 1449
 0.33
chr6_44797257_44797514 0.16 SUPT3H
 suppressor of Ty 3 homolog (S. cerevisiae)
 125862
 0.06
chr8_127567681_127568033 0.16 RP11-103H7.5
1284
 0.38
chr13_41574006_41574157 0.16 ELF1
 E74-like factor 1 (ets domain transcription factor)
 17663
 0.19
chr9_86303237_86303482 0.16 RP11-522I20.3
19150
 0.17
chr1_226911013_226911201 0.16 ITPKB
 inositol-trisphosphate 3-kinase B
 14052
 0.21
chr18_19178052_19178356 0.16 ESCO1
 establishment of sister chromatid cohesion N-acetyltransferase 1
 2493
 0.23
chr12_111005224_111005381 0.16 PPTC7
 PTC7 protein phosphatase homolog (S. cerevisiae)
 15823
 0.14
chr1_235014905_235015056 0.16 ENSG00000239690
 .
 24953
 0.21
chr16_73092870_73093114 0.16 ZFHX3
 zinc finger homeobox 3
 605
 0.79
chr4_38518191_38518342 0.16 RP11-617D20.1
107930
 0.07
chr14_92322968_92323119 0.16 TC2N
 tandem C2 domains, nuclear
 10830
 0.2
chr3_101229742_101229893 0.16 SENP7
 SUMO1/sentrin specific peptidase 7
 2211
 0.26
chr2_106375349_106375537 0.16 NCK2
 NCK adaptor protein 2
 13255
 0.28
chr2_222385882_222386088 0.16 ENSG00000221432
 .
 1608
 0.44
chr9_31336901_31337115 0.16 ENSG00000211510
 .
 562782
 0.0
chr5_75626248_75626505 0.16 RP11-466P24.6
19089
 0.25
chrX_78338727_78338878 0.15 GPR174
 G protein-coupled receptor 174
 87667
 0.1
chr10_4178314_4178722 0.15 KLF6
 Kruppel-like factor 6
 351045
 0.01
chr5_141503692_141503877 0.15 NDFIP1
 Nedd4 family interacting protein 1
 15714
 0.23
chrX_20456293_20456479 0.15 ENSG00000252978
 .
 13840
 0.3
chr13_48760783_48760934 0.15 ITM2B
 integral membrane protein 2B
 46436
 0.16
chr5_56145818_56146186 0.15 ENSG00000238717
 .
 6973
 0.16
chr15_38959465_38959802 0.15 C15orf53
 chromosome 15 open reading frame 53
 29166
 0.22
chr6_35635066_35635406 0.15 ENSG00000265527
 .
 2670
 0.2
chr19_14461542_14461693 0.15 CD97
 CD97 molecule
 30351
 0.13
chr2_106402335_106402603 0.15 NCK2
 NCK adaptor protein 2
 30546
 0.22
chr5_61873952_61874158 0.15 LRRC70
 leucine rich repeat containing 70
 507
 0.52
chr17_4263545_4263821 0.15 ENSG00000263882
 .
 4065
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of VAX2_RHOXF2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0001878 response to yeast(GO:0001878)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.2 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.0 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.3 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0060510 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0050856 regulation of T cell receptor signaling pathway(GO:0050856)
0.0 0.0 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.0 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0 0.1 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.0 GO:0033088 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.0 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.2 GO:0008347 glial cell migration(GO:0008347)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:2001234 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:1904376 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.0 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.1 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.0 GO:0015825 L-serine transport(GO:0015825)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.0 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0043628 ncRNA 3'-end processing(GO:0043628)
0.0 0.1 GO:0032527 protein exit from endoplasmic reticulum(GO:0032527)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.3 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.0 GO:0015705 iodide transport(GO:0015705)
0.0 0.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.0 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0033081 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.0 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.0 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.0 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.0 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.0 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.0 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.0 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.3 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.2 GO:0001846 opsonin binding(GO:0001846)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0048156 tau protein binding(GO:0048156)
0.0 0.0 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.0 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.1 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.0 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.0 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.3 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.0 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.0 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling