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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for VSX1

Z-value: 1.29

Motif logo

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Transcription factors associated with VSX1

Gene Symbol Gene ID Gene Info
VSX1
ENSG00000100987.10 visual system homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr20_25071203_25071354VSX182820.211093-0.826.9e-03Click!
chr20_25057715_25057866VSX149770.223332-0.791.1e-02Click!
chr20_25071716_25071887VSX188050.209608-0.742.1e-02Click!
chr20_25064708_25064859VSX117870.376087-0.684.5e-02Click!
chr20_25058000_25058151VSX146920.227015-0.646.5e-02Click!

Activity of the VSX1 motif across conditions

Conditions sorted by the z-value of the VSX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_33934050_33934291 0.77 LMO2
 LIM domain only 2 (rhombotin-like 1)
 20334
 0.2
chr12_89453867_89454269 0.67 ENSG00000238302
 .
 221994
 0.02
chr14_101308246_101309004 0.63 ENSG00000214548
 .
 7020
 0.04
chr4_140958813_140959347 0.55 RP11-392B6.1
90089
 0.09
chr20_30743365_30743658 0.54 ENSG00000265736
 .
 36957
 0.11
chr2_66735450_66735818 0.50 MEIS1
 Meis homeobox 1
 425
 0.88
chr8_27501056_27501559 0.49 SCARA3
 scavenger receptor class A, member 3
 9609
 0.16
chr3_70882578_70882827 0.49 ENSG00000206939
 .
 25201
 0.23
chr2_207972754_207973110 0.48 ENSG00000253008
 .
 1865
 0.35
chr8_108208326_108208625 0.46 ENSG00000211995
 .
 58251
 0.16
chr12_26811451_26811602 0.46 RP11-666F17.1
35224
 0.22
chr14_100240950_100241315 0.45 EML1
 echinoderm microtubule associated protein like 1
 1091
 0.59
chr12_109060942_109061130 0.44 ENSG00000238457
 .
 1188
 0.4
chr6_85293592_85293821 0.44 RP11-132M7.3
105437
 0.08
chr6_37669094_37669483 0.42 MDGA1
 MAM domain containing glycosylphosphatidylinositol anchor 1
 2206
 0.4
chr9_107630817_107631231 0.41 RP11-217B7.2
58810
 0.12
chr2_36720605_36720756 0.41 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 20153
 0.19
chr8_145562069_145562399 0.41 SCRT1
 scratch family zinc finger 1
 2291
 0.12
chr17_26498050_26498459 0.41 PYY2
 peptide YY, 2 (pseudogene)
 56078
 0.09
chr6_39787204_39787470 0.40 DAAM2
 dishevelled associated activator of morphogenesis 2
 26543
 0.21
chr7_41910301_41910559 0.40 AC005027.3
165497
 0.04
chr17_66379311_66379462 0.39 ENSG00000207561
 .
 41303
 0.14
chr8_116430587_116430872 0.39 TRPS1
 trichorhinophalangeal syndrome I
 73719
 0.12
chr4_7649546_7649747 0.39 SORCS2
 sortilin-related VPS10 domain containing receptor 2
 86361
 0.09
chr9_94154220_94154371 0.39 AUH
 AU RNA binding protein/enoyl-CoA hydratase
 30100
 0.21
chr3_188692042_188692831 0.38 TPRG1
 tumor protein p63 regulated 1
 27433
 0.27
chr17_13316675_13316828 0.38 ENSG00000266115
 .
 86894
 0.1
chr4_167261736_167261962 0.37 ENSG00000206711
 .
 27663
 0.26
chr1_32123952_32124158 0.37 RP11-73M7.6
1196
 0.35
chrX_39586002_39586188 0.36 ENSG00000264618
 .
 59982
 0.14
chr10_20884985_20885136 0.36 ENSG00000265372
 .
 44161
 0.21
chr1_118238359_118238510 0.36 ENSG00000212266
 .
 7070
 0.28
chr9_90131509_90131738 0.35 DAPK1
 death-associated protein kinase 1
 17703
 0.23
chr2_38054791_38055066 0.35 CDC42EP3
 CDC42 effector protein (Rho GTPase binding) 3
 89317
 0.09
chr3_171978629_171978920 0.35 ENSG00000243398
 .
 23658
 0.19
chr12_56917827_56917978 0.35 RBMS2
 RNA binding motif, single stranded interacting protein 2
 2119
 0.23
chr3_129311849_129312381 0.35 ENSG00000239437
 .
 1923
 0.28
chr2_80220201_80220486 0.34 AC016716.2
37334
 0.22
chr8_86971952_86972334 0.34 ATP6V0D2
 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
 27409
 0.23
chr14_77873001_77873391 0.34 FKSG61
9545
 0.11
chr13_108486642_108486793 0.34 FAM155A-IT1
 FAM155A intronic transcript 1 (non-protein coding)
 1082
 0.62
chr12_118770370_118770546 0.34 TAOK3
 TAO kinase 3
 26452
 0.21
chr11_118393531_118393828 0.34 TTC36
 tetratricopeptide repeat domain 36
 4508
 0.12
chr14_24837858_24838637 0.34 NFATC4
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
 41
 0.94
chr21_39659541_39659821 0.33 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 8798
 0.29
chr4_57597998_57598267 0.33 HOPX
 HOP homeobox
 50067
 0.12
chr7_75952019_75952170 0.33 HSPB1
 heat shock 27kDa protein 1
 19200
 0.14
chr13_27597624_27597775 0.33 USP12-AS1
 USP12 antisense RNA 1
 139293
 0.04
chr3_71030532_71030802 0.33 FOXP1
 forkhead box P1
 83410
 0.1
chr1_149743371_149743522 0.33 FCGR1A
 Fc fragment of IgG, high affinity Ia, receptor (CD64)
 10781
 0.09
chr7_130904360_130904511 0.33 MKLN1
 muskelin 1, intracellular mediator containing kelch motifs
 65386
 0.12
chr21_40856650_40856801 0.33 SH3BGR
 SH3 domain binding glutamic acid-rich protein
 15024
 0.18
chr13_101539869_101540020 0.33 NALCN-AS1
 NALCN antisense RNA 1
 179365
 0.03
chr15_85548703_85549030 0.33 PDE8A
 phosphodiesterase 8A
 23654
 0.18
chr10_94756810_94756961 0.32 EXOC6
 exocyst complex component 6
 346
 0.91
chr20_19478003_19478154 0.32 ENSG00000216017
 .
 92753
 0.08
chr2_200604102_200604338 0.32 FTCDNL1
 formiminotransferase cyclodeaminase N-terminal like
 111376
 0.07
chr10_79021361_79021706 0.31 RP11-328K22.1
52166
 0.15
chr8_11319032_11319411 0.31 FAM167A
 family with sequence similarity 167, member A
 5055
 0.17
chr3_12632091_12632446 0.31 RAF1
 v-raf-1 murine leukemia viral oncogene homolog 1
 18477
 0.14
chr10_17217462_17217735 0.31 TRDMT1
 tRNA aspartic acid methyltransferase 1
 939
 0.58
chr11_20111347_20111612 0.31 NAV2-AS1
 NAV2 antisense RNA 1
 30699
 0.17
chr8_20125798_20125949 0.31 LZTS1
 leucine zipper, putative tumor suppressor 1
 13070
 0.19
chr4_89647157_89647308 0.31 FAM13A-AS1
 FAM13A antisense RNA 1
 4366
 0.21
chr1_208250614_208250765 0.31 CD34
 CD34 molecule
 165942
 0.04
chr9_112955106_112955494 0.31 C9orf152
 chromosome 9 open reading frame 152
 15169
 0.23
chr5_15249746_15249921 0.31 ENSG00000202269
 .
 138804
 0.05
chr14_77238822_77239041 0.31 VASH1
 vasohibin 1
 5418
 0.19
chr10_30831887_30832121 0.31 ENSG00000239744
 .
 12829
 0.24
chr10_70089432_70089583 0.31 HNRNPH3
 heterogeneous nuclear ribonucleoprotein H3 (2H9)
 2325
 0.26
chr1_201706190_201706778 0.31 RP11-90L20.2
150
 0.93
chr15_57574971_57575503 0.31 TCF12
 transcription factor 12
 584
 0.78
chr18_32694549_32694734 0.30 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
 73027
 0.11
chr18_54126758_54127059 0.30 TXNL1
 thioredoxin-like 1
 154814
 0.04
chr4_122569979_122570130 0.30 ANXA5
 annexin A5
 48063
 0.16
chr3_105699405_105699556 0.30 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 111084
 0.08
chr9_81321983_81322311 0.30 PSAT1
 phosphoserine aminotransferase 1
 410088
 0.01
chr11_14562787_14563173 0.30 PSMA1
 proteasome (prosome, macropain) subunit, alpha type, 1
 20738
 0.2
chr11_126084700_126085013 0.30 ENSG00000222067
 .
 483
 0.66
chr7_80348902_80349053 0.30 CD36
 CD36 molecule (thrombospondin receptor)
 46285
 0.2
chr11_16377737_16377888 0.30 SOX6
 SRY (sex determining region Y)-box 6
 14997
 0.3
chr8_91795476_91795627 0.30 NECAB1
 N-terminal EF-hand calcium binding protein 1
 8227
 0.21
chr2_158326449_158327167 0.29 CYTIP
 cytohesin 1 interacting protein
 18533
 0.22
chr12_66270554_66270788 0.29 RP11-366L20.2
 Uncharacterized protein
 4687
 0.21
chr6_14638853_14639371 0.29 ENSG00000206960
 .
 7654
 0.34
chr9_125766060_125766211 0.29 RABGAP1
 RAB GTPase activating protein 1
 29653
 0.12
chr11_131479604_131479755 0.29 NTM
 neurotrimin
 27774
 0.2
chr1_100976278_100976464 0.29 RP5-837M10.4
24818
 0.19
chr7_16568149_16568300 0.29 LRRC72
 leucine rich repeat containing 72
 1703
 0.34
chr12_1727335_1727720 0.29 WNT5B
 wingless-type MMTV integration site family, member 5B
 1305
 0.46
chr3_72036989_72037274 0.29 ENSG00000239250
 .
 160803
 0.04
chr17_29925275_29925666 0.29 ENSG00000199187
 .
 23040
 0.11
chr12_71040223_71040434 0.29 PTPRB
 protein tyrosine phosphatase, receptor type, B
 9108
 0.29
chr5_123171717_123171868 0.29 CSNK1G3
 casein kinase 1, gamma 3
 247673
 0.02
chr4_187545719_187545870 0.29 FAT1
 FAT atypical cadherin 1
 26616
 0.2
chr6_22821870_22822021 0.29 HDGFL1
 hepatoma derived growth factor-like 1
 252150
 0.02
chr18_5516139_5516334 0.29 EPB41L3
 erythrocyte membrane protein band 4.1-like 3
 5186
 0.21
chr8_80226395_80226546 0.29 ENSG00000264969
 .
 216872
 0.02
chr7_92382094_92382391 0.28 ENSG00000206763
 .
 51114
 0.14
chr3_99672505_99672656 0.28 ENSG00000264897
 .
 10662
 0.27
chr5_17282736_17283060 0.28 ENSG00000252908
 .
 42178
 0.15
chr2_36680268_36680419 0.28 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 60490
 0.12
chr3_43827332_43827483 0.28 ABHD5
 abhydrolase domain containing 5
 74208
 0.11
chr1_221187846_221187997 0.28 HLX
 H2.0-like homeobox
 133337
 0.05
chr15_67006142_67006408 0.28 SMAD6
 SMAD family member 6
 2240
 0.39
chr19_5955434_5955585 0.28 RANBP3
 RAN binding protein 3
 22581
 0.09
chr12_24383050_24383201 0.28 ENSG00000216192
 .
 17770
 0.3
chr20_56050830_56050981 0.28 CTCFL
 CCCTC-binding factor (zinc finger protein)-like
 48408
 0.12
chr5_146917975_146918126 0.28 DPYSL3
 dihydropyrimidinase-like 3
 28431
 0.24
chr11_112036083_112036234 0.28 IL18
 interleukin 18 (interferon-gamma-inducing factor)
 1318
 0.25
chr1_200332138_200332309 0.28 ZNF281
 zinc finger protein 281
 46897
 0.19
chr2_98708440_98708797 0.28 VWA3B
 von Willebrand factor A domain containing 3B
 4919
 0.31
chr18_65188248_65188399 0.27 DSEL
 dermatan sulfate epimerase-like
 4106
 0.29
chr11_103924198_103924349 0.27 PDGFD
 platelet derived growth factor D
 16519
 0.22
chr17_30586530_30586681 0.27 RHBDL3
 rhomboid, veinlet-like 3 (Drosophila)
 6590
 0.16
chr2_98546607_98546758 0.27 ENSG00000238719
 .
 17102
 0.21
chr7_77130046_77130330 0.27 PTPN12
 protein tyrosine phosphatase, non-receptor type 12
 36404
 0.19
chr18_60117683_60118024 0.27 ZCCHC2
 zinc finger, CCHC domain containing 2
 72387
 0.1
chr12_26171601_26171752 0.27 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
 2697
 0.33
chr11_63278500_63278680 0.27 LGALS12
 lectin, galactoside-binding, soluble, 12
 3131
 0.21
chr20_43176865_43177016 0.27 PKIG
 protein kinase (cAMP-dependent, catalytic) inhibitor gamma
 16370
 0.14
chr10_6390281_6390901 0.27 DKFZP667F0711
1687
 0.47
chr15_50392799_50393114 0.27 ATP8B4
 ATPase, class I, type 8B, member 4
 13745
 0.23
chr9_5450626_5450802 0.27 CD274
 CD274 molecule
 189
 0.95
chr11_34338329_34338672 0.27 ABTB2
 ankyrin repeat and BTB (POZ) domain containing 2
 40302
 0.19
chr5_153350030_153350181 0.27 FAM114A2
 family with sequence similarity 114, member A2
 66765
 0.12
chr6_144126645_144127098 0.27 LTV1
 LTV1 homolog (S. cerevisiae)
 37610
 0.18
chr6_82477389_82477689 0.27 ENSG00000206886
 .
 3798
 0.25
chr7_91513061_91513319 0.27 MTERF
 mitochondrial transcription termination factor
 3156
 0.35
chr1_149358385_149358581 0.27 FCGR1C
 Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
 10811
 0.14
chr10_80893653_80893925 0.27 ZMIZ1
 zinc finger, MIZ-type containing 1
 64997
 0.13
chr2_145270130_145270606 0.27 ZEB2
 zinc finger E-box binding homeobox 2
 4747
 0.27
chr21_37360811_37360962 0.27 RUNX1
 runt-related transcription factor 1
 16079
 0.16
chr9_8718077_8718278 0.27 PTPRD
 protein tyrosine phosphatase, receptor type, D
 15717
 0.22
chr11_61467806_61468091 0.27 DAGLA
 diacylglycerol lipase, alpha
 20043
 0.15
chr3_16005968_16006176 0.27 ENSG00000207815
 .
 90794
 0.08
chr8_72770819_72770970 0.27 MSC
 musculin
 14191
 0.18
chr6_82476723_82477129 0.26 ENSG00000206886
 .
 3185
 0.27
chr8_105598551_105598718 0.26 LRP12
 low density lipoprotein receptor-related protein 12
 2600
 0.3
chr3_151122388_151122772 0.26 P2RY12
 purinergic receptor P2Y, G-protein coupled, 12
 19980
 0.18
chr3_71297288_71297645 0.26 FOXP1
 forkhead box P1
 3150
 0.35
chr6_70294956_70295144 0.26 ENSG00000265362
 .
 36215
 0.23
chr12_124474900_124475063 0.26 ZNF664
 zinc finger protein 664
 17139
 0.08
chr4_141058656_141058807 0.26 RP11-392B6.1
9562
 0.23
chr12_109003340_109003491 0.26 TMEM119
 transmembrane protein 119
 11319
 0.13
chr3_114951923_114952074 0.26 ZBTB20
 zinc finger and BTB domain containing 20
 85880
 0.11
chr8_41786362_41786614 0.26 KAT6A
 K(lysine) acetyltransferase 6A
 29393
 0.17
chr13_47317430_47317715 0.26 ESD
 esterase D
 38131
 0.19
chr1_222507571_222507774 0.26 ENSG00000222399
 .
 169405
 0.03
chr1_209465302_209465601 0.26 ENSG00000230937
 .
 140027
 0.05
chr4_120580539_120580789 0.26 PDE5A
 phosphodiesterase 5A, cGMP-specific
 30518
 0.22
chr12_19805873_19806024 0.26 ENSG00000200885
 .
 71421
 0.13
chr3_124869997_124870148 0.26 ENSG00000264986
 .
 324
 0.89
chr11_67886734_67886961 0.26 CHKA
 choline kinase alpha
 1448
 0.32
chr14_72179521_72179805 0.26 SIPA1L1
 signal-induced proliferation-associated 1 like 1
 94190
 0.09
chr3_72059056_72059299 0.26 ENSG00000239250
 .
 182849
 0.03
chr11_34438827_34438978 0.26 CAT
 catalase
 21570
 0.21
chr3_18585987_18586243 0.25 ENSG00000228956
 .
 17451
 0.28
chr10_115033205_115033385 0.25 ENSG00000238380
 .
 79889
 0.11
chr18_9704973_9705544 0.25 RAB31
 RAB31, member RAS oncogene family
 2904
 0.31
chr4_52798315_52798466 0.25 DCUN1D4
 DCN1, defective in cullin neddylation 1, domain containing 4
 40417
 0.19
chr1_178102702_178103151 0.25 RASAL2
 RAS protein activator like 2
 39650
 0.22
chr6_154808814_154808965 0.25 CNKSR3
 CNKSR family member 3
 9264
 0.31
chr14_75428743_75429108 0.25 PGF
 placental growth factor
 6438
 0.15
chr18_10269165_10269316 0.25 ENSG00000239031
 .
 120757
 0.06
chr16_85295971_85296292 0.25 ENSG00000266307
 .
 43800
 0.16
chr10_62109936_62110087 0.25 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 39477
 0.23
chr9_4927697_4927848 0.25 ENSG00000238362
 .
 40325
 0.13
chr12_57620818_57620969 0.25 ENSG00000202067
 .
 864
 0.38
chr2_58926103_58926452 0.25 FANCL
 Fanconi anemia, complementation group L
 457770
 0.01
chr1_64208231_64208526 0.25 ROR1
 receptor tyrosine kinase-like orphan receptor 1
 31315
 0.2
chr7_40803485_40803636 0.25 AC005160.3
11597
 0.32
chr20_43330295_43330446 0.25 RP11-445H22.3
5633
 0.14
chr5_176901771_176902224 0.25 DBN1
 drebrin 1
 595
 0.56
chr9_95298761_95298917 0.25 ECM2
 extracellular matrix protein 2, female organ and adipocyte specific
 98
 0.97
chr5_67829635_67829905 0.25 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 241374
 0.02
chr10_17064484_17064884 0.25 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 38490
 0.2
chr1_35309309_35309515 0.25 RP5-997D16.2
6883
 0.15
chr13_41639811_41639962 0.25 WBP4
 WW domain binding protein 4
 4190
 0.18
chr10_73000505_73000775 0.25 UNC5B-AS1
 UNC5B antisense RNA 1
 22655
 0.16
chr10_102813488_102813726 0.25 KAZALD1
 Kazal-type serine peptidase inhibitor domain 1
 7991
 0.12
chr6_148845405_148845556 0.24 ENSG00000223322
 .
 104
 0.98
chr7_141061897_141062048 0.24 RP5-842K16.2
69096
 0.12
chr6_135740137_135740472 0.24 AHI1
 Abelson helper integration site 1
 7658
 0.26
chr1_221096418_221096569 0.24 HLX
 H2.0-like homeobox
 41909
 0.16
chr4_169536059_169536210 0.24 PALLD
 palladin, cytoskeletal associated protein
 16632
 0.21
chr17_67925463_67925614 0.24 ENSG00000252100
 .
 19550
 0.24
chr3_155926514_155926665 0.24 KCNAB1-AS2
 KCNAB1 antisense RNA 2
 19083
 0.25
chr5_58473985_58474185 0.24 PDE4D
 phosphodiesterase 4D, cAMP-specific
 97860
 0.09
chr15_71824033_71824261 0.24 THSD4
 thrombospondin, type I, domain containing 4
 15428
 0.25
chr3_81913343_81913495 0.24 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 102107
 0.09
chr12_20000530_20000725 0.24 ENSG00000200885
 .
 123258
 0.06
chr13_77319833_77320172 0.24 KCTD12
 potassium channel tetramerization domain containing 12
 140523
 0.05
chr19_39157057_39157758 0.24 ACTN4
 actinin, alpha 4
 19029
 0.11
chr2_36780540_36780944 0.24 AC007401.2
 Uncharacterized protein
 1331
 0.45
chrX_124435894_124436045 0.24 ENSG00000263886
 .
 14344
 0.31
chr11_69264697_69264848 0.24 CCND1
 cyclin D1
 191083
 0.03
chr1_213499715_213500068 0.24 RPS6KC1
 ribosomal protein S6 kinase, 52kDa, polypeptide 1
 275287
 0.01
chr20_50419228_50419379 0.24 SALL4
 spalt-like transcription factor 4
 244
 0.94
chr5_124202510_124202693 0.24 ZNF608
 zinc finger protein 608
 118101
 0.05

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of VSX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.4 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.3 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0007132 meiotic metaphase I(GO:0007132)
0.1 0.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.2 GO:0071436 sodium ion export(GO:0071436)
0.1 0.2 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.2 GO:0060437 lung growth(GO:0060437)
0.1 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.1 GO:0010193 response to ozone(GO:0010193)
0.1 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.2 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.3 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.1 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.4 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0021508 floor plate formation(GO:0021508)
0.0 0.1 GO:0021825 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0043301 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.0 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.2 GO:0060760 positive regulation of response to cytokine stimulus(GO:0060760)
0.0 0.2 GO:1901532 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.3 GO:0009650 UV protection(GO:0009650)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.0 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0030540 female genitalia development(GO:0030540)
0.0 0.1 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) regulation of membrane lipid distribution(GO:0097035)
0.0 0.1 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.0 GO:0048342 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.0 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.0 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.1 GO:0055093 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0042663 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:2000647 negative regulation of stem cell proliferation(GO:2000647)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.0 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:0007320 insemination(GO:0007320)
0.0 0.1 GO:0010875 positive regulation of cholesterol efflux(GO:0010875)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0016241 regulation of macroautophagy(GO:0016241)
0.0 0.1 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0051788 response to misfolded protein(GO:0051788)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.0 GO:0034694 response to prostaglandin(GO:0034694)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.0 GO:0002246 wound healing involved in inflammatory response(GO:0002246) connective tissue replacement involved in inflammatory response wound healing(GO:0002248) inflammatory response to wounding(GO:0090594) connective tissue replacement(GO:0097709)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.0 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.0 0.1 GO:0031652 regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0010755 regulation of plasminogen activation(GO:0010755) negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.2 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.1 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.0 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.0 GO:0001660 fever generation(GO:0001660)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0046449 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.0 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0071025 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.0 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.0 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.0 GO:0051883 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.0 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.0 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.0 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.0 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.6 GO:0030016 myofibril(GO:0030016)
0.0 0.3 GO:0030018 Z disc(GO:0030018)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0042641 actomyosin(GO:0042641)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.0 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.0 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0030354 melanin-concentrating hormone activity(GO:0030354)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.0 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0015368 calcium:cation antiporter activity(GO:0015368)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.0 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.0 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.0 GO:0045569 TRAIL binding(GO:0045569)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.0 PID SHP2 PATHWAY SHP2 signaling
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM Genes involved in Cytokine Signaling in Immune system
0.1 0.1 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.0 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)