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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for XBP1

Z-value: 1.90

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Transcription factors associated with XBP1

Gene Symbol	Gene ID	Gene Info
XBP1 Ensembl NCBI GeneCards UniProt	ENSG00000100219.12	X-box binding protein 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr22_29195216_29195505	XBP1	761	0.481646	0.80	1.0e-02	Click!
chr22_29194942_29195160	XBP1	1070	0.370646	0.75	2.0e-02	Click!
chr22_29187614_29187797	XBP1	8416	0.134526	0.69	3.9e-02	Click!
chr22_29195515_29195759	XBP1	484	0.634708	0.63	6.9e-02	Click!
chr22_29191174_29191325	XBP1	4872	0.149292	0.49	1.8e-01	Click!

Activity of the XBP1 motif across conditions

Conditions sorted by the z-value of the XBP1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_73866536_73866921	0.77	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	17938	0.2
chr3_71491271_71491489	0.74	ENSG00000221264	.	99860	0.07
chr12_121665055_121665206	0.73	P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4	17162	0.17
chr22_19493250_19493427	0.68	CLDN5	claudin 5	19568	0.11
chr2_240253273_240253424	0.68	ENSG00000264292	.	20151	0.16
chr7_30188840_30189132	0.66	MTURN	maturin, neural progenitor differentiation regulator homolog (Xenopus)	3473	0.2
chr1_1164425_1164576	0.66	SDF4	stromal cell derived factor 4	524	0.55
chr7_135656597_135656786	0.64	MTPN	myotrophin	5373	0.18
chr6_90856941_90857269	0.64	ENSG00000222078	.	145880	0.04
chr5_121413529_121413763	0.63	LOX	lysyl oxidase	334	0.91
chr5_179494304_179494455	0.59	RNF130	ring finger protein 130	4342	0.24
chr8_109256097_109256248	0.58	EIF3E	eukaryotic translation initiation factor 3, subunit E	4725	0.28
chr2_33823948_33824099	0.58	FAM98A	family with sequence similarity 98, member A	321	0.92
chr19_8553065_8553234	0.58	HNRNPM	heterogeneous nuclear ribonucleoprotein M	2107	0.21
chr2_191274383_191274572	0.58	MFSD6	major facilitator superfamily domain containing 6	1396	0.45
chr14_103273974_103274344	0.58	ENSG00000238853	.	18231	0.16
chr2_74709149_74709337	0.58	CCDC142	coiled-coil domain containing 142	880	0.24
chr11_10562075_10562226	0.57	RNF141	ring finger protein 141	303	0.73
chr14_104337931_104338272	0.57	PPP1R13B	protein phosphatase 1, regulatory subunit 13B	24174	0.14
chr18_13425280_13425583	0.57	LDLRAD4-AS1	LDLRAD4 antisense RNA 1	2048	0.24
chr14_99647919_99648070	0.56	AL162151.4		23241	0.23
chr5_1268781_1268932	0.56	TERT	telomerase reverse transcriptase	26248	0.14
chr15_30472324_30472499	0.55	ENSG00000221785	.	35331	0.11
chr3_40892425_40892576	0.54	ZNF621	zinc finger protein 621	325593	0.01
chr1_16176295_16176533	0.54	RP11-169K16.9		1772	0.26
chr6_150184001_150184188	0.54	RP11-244K5.8		361	0.72
chr10_6542814_6542965	0.52	PRKCQ	protein kinase C, theta	79312	0.11
chr8_143385130_143385421	0.52	TSNARE1	t-SNARE domain containing 1	50849	0.13
chr1_25281062_25281213	0.51	RP11-84D1.1		6699	0.22
chr3_45152072_45152512	0.50	CDCP1	CUB domain containing protein 1	35622	0.16
chr9_92123694_92124049	0.50	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	10826	0.22
chr10_6515506_6515719	0.50	PRKCQ	protein kinase C, theta	106589	0.07
chr11_281660_281836	0.50	NLRP6	NLR family, pyrin domain containing 6	3178	0.1
chr3_28389894_28390045	0.49	AZI2	5-azacytidine induced 2	1	0.94
chr7_2751932_2752083	0.49	AMZ1	archaelysin family metallopeptidase 1	24171	0.18
chr1_26869946_26870282	0.49	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	511	0.72
chr1_206853825_206853976	0.49	ENSG00000252853	.	1408	0.34
chr1_204485874_204486061	0.48	MDM4	Mdm4 p53 binding protein homolog (mouse)	348	0.87
chr2_47205897_47206474	0.48	RP11-15I20.1		22158	0.15
chr2_60772484_60772807	0.48	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	7895	0.25
chr8_2049748_2049899	0.48	MYOM2	myomesin 2	56639	0.16
chr16_56966719_56966870	0.48	HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	302	0.83
chr5_14702616_14702781	0.47	FAM105B	family with sequence similarity 105, member B	21039	0.19
chr21_43510201_43510352	0.46	C21orf128	chromosome 21 open reading frame 128	18368	0.17
chr15_68502161_68502336	0.46	CALML4	calmodulin-like 4	3831	0.2
chr19_5322287_5322481	0.46	PTPRS	protein tyrosine phosphatase, receptor type, S	18430	0.23
chr19_39370042_39370193	0.46	RINL	Ras and Rab interactor-like	1198	0.24
chr7_21398317_21398636	0.46	ENSG00000195024	.	22505	0.21
chr12_4224775_4225225	0.46	CCND2	cyclin D2	157938	0.03
chr18_57025739_57025916	0.45	LMAN1	lectin, mannose-binding, 1	1367	0.48
chr12_53007493_53007644	0.45	KRT73	keratin 73	1548	0.23
chr19_13302093_13302244	0.45	CTC-250I14.6		37161	0.09
chr1_92350648_92350876	0.45	TGFBR3	transforming growth factor, beta receptor III	904	0.63
chr9_101984883_101985113	0.45	SEC61B	Sec61 beta subunit	415	0.66
chr16_89831132_89831287	0.44	FANCA	Fanconi anemia, complementation group A	19739	0.11
chr10_115440408_115440560	0.44	CASP7	caspase 7, apoptosis-related cysteine peptidase	785	0.64
chr1_204419360_204419573	0.44	PIK3C2B	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	17008	0.17
chr2_62514408_62514559	0.43	ENSG00000238809	.	22353	0.18
chr17_80222138_80222289	0.43	AC132872.2	CDNA FLJ27256 fis, clone SYN09689; Uncharacterized protein	8082	0.11
chr3_50611055_50611206	0.43	C3orf18	chromosome 3 open reading frame 18	2708	0.2
chr9_134487356_134487507	0.43	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	9794	0.22
chr14_61905607_61905881	0.43	PRKCH	protein kinase C, eta	3532	0.31
chr10_134184917_134185068	0.43	PWWP2B	PWWP domain containing 2B	25680	0.15
chr11_14599828_14600029	0.42	PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	57686	0.12
chr2_25482333_25482484	0.42	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	7228	0.23
chr12_49245553_49245704	0.42	DDX23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23	296	0.81
chr3_156271748_156272097	0.42	SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)	8	0.98
chr1_12680857_12681037	0.42	DHRS3	dehydrogenase/reductase (SDR family) member 3	3210	0.23
chr18_74099073_74099373	0.41	ZNF516	zinc finger protein 516	8355	0.22
chr1_151030936_151031087	0.41	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	777	0.35
chr21_45563429_45563580	0.41	C21orf33	chromosome 21 open reading frame 33	7503	0.15
chr3_32457185_32457532	0.41	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	23827	0.21
chr20_24823319_24823470	0.41	CST7	cystatin F (leukocystatin)	106472	0.07
chr17_18907669_18907835	0.41	FAM83G	family with sequence similarity 83, member G	201	0.91
chr3_71470931_71471210	0.40	FOXP1	forkhead box P1	117159	0.06
chr16_68404588_68404885	0.40	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	172	0.93
chr2_99097622_99097974	0.40	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa	36385	0.18
chr8_100025991_100026384	0.40	VPS13B	vacuolar protein sorting 13 homolog B (yeast)	685	0.69
chr14_106967042_106967318	0.40	IGHV1-46	immunoglobulin heavy variable 1-46	608	0.35
chr1_44730028_44730179	0.40	ERI3-IT1	ERI3 intronic transcript 1 (non-protein coding)	20158	0.16
chr6_138145788_138146005	0.40	RP11-356I2.4		1135	0.55
chr5_130868870_130869280	0.39	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	349	0.93
chr2_95872709_95872896	0.39	ZNF2	zinc finger protein 2	41240	0.13
chr5_121413787_121413938	0.39	LOX	lysyl oxidase	118	0.97
chr1_207669922_207670112	0.39	CR1	complement component (3b/4b) receptor 1 (Knops blood group)	331	0.89
chr9_133454524_133454675	0.39	FUBP3	far upstream element (FUSE) binding protein 3	394	0.89
chr16_2610384_2610566	0.39	RP11-20I23.13		4414	0.07
chr5_75743301_75743452	0.39	IQGAP2	IQ motif containing GTPase activating protein 2	43127	0.18
chr22_31348065_31348216	0.39	MORC2	MORC family CW-type zinc finger 2	16047	0.14
chr17_72375790_72375941	0.39	GPR142	G protein-coupled receptor 142	12268	0.11
chr17_78389416_78389765	0.39	ENDOV	endonuclease V	121	0.88
chr10_74040371_74040522	0.38	RP11-442H21.2		4708	0.18
chr20_31110520_31110671	0.38	C20orf112	chromosome 20 open reading frame 112	1938	0.32
chr13_100026653_100026804	0.38	ENSG00000207719	.	18343	0.2
chr17_75883728_75883949	0.38	FLJ45079		5179	0.25
chr6_170403305_170403456	0.38	RP11-302L19.1		74361	0.11
chr16_67581546_67581764	0.38	FAM65A	family with sequence similarity 65, member A	3358	0.11
chr11_63656801_63657461	0.37	MARK2	MAP/microtubule affinity-regulating kinase 2	963	0.45
chr13_41188423_41188902	0.37	FOXO1	forkhead box O1	52072	0.14
chr6_37141824_37141975	0.37	PIM1	pim-1 oncogene	3920	0.22
chr7_157644645_157644994	0.37	AC011899.9		2402	0.35
chr10_52382609_52382760	0.37	SGMS1	sphingomyelin synthase 1	1059	0.45
chr4_47707432_47707640	0.37	CORIN	corin, serine peptidase	84741	0.09
chr2_175199670_175199954	0.37	SP9	Sp9 transcription factor	138	0.95
chr16_70441933_70442106	0.37	ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	7478	0.13
chr3_69115410_69115561	0.36	TMF1	TATA element modulatory factor 1	14001	0.12
chr20_55204811_55205013	0.36	TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	378	0.84
chr3_176888184_176888459	0.36	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	25890	0.2
chr15_22482874_22483025	0.36	IGHV1OR15-4	immunoglobulin heavy variable 1/OR15-4 (pseudogene)	319	0.84
chr16_89002649_89002800	0.36	RP11-830F9.7		1440	0.29
chr16_85650575_85650806	0.36	GSE1	Gse1 coiled-coil protein	3732	0.25
chr6_130009100_130009346	0.36	ARHGAP18	Rho GTPase activating protein 18	22147	0.24
chr11_65648439_65648640	0.36	CTSW	cathepsin W	1210	0.23
chr7_30066018_30066290	0.36	FKBP14	FK506 binding protein 14, 22 kDa	146	0.94
chr3_46482772_46482982	0.36	LTF	lactotransferrin	22284	0.13
chr2_238612428_238612611	0.35	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	11537	0.23
chr1_85930252_85930569	0.35	DDAH1	dimethylarginine dimethylaminohydrolase 1	143	0.97
chr15_90774705_90774999	0.35	GDPGP1	GDP-D-glucose phosphorylase 1	2188	0.18
chr18_13273705_13274004	0.35	LDLRAD4	low density lipoprotein receptor class A domain containing 4	4248	0.23
chr9_29212913_29213411	0.35	ENSG00000215939	.	324209	0.01
chr17_81041562_81041843	0.35	METRNL	meteorin, glial cell differentiation regulator-like	247	0.94
chr19_40696633_40696945	0.35	MAP3K10	mitogen-activated protein kinase kinase kinase 10	862	0.48
chr10_70749019_70749469	0.35	KIAA1279	KIAA1279	757	0.62
chr10_6109522_6109819	0.35	IL2RA	interleukin 2 receptor, alpha	5382	0.17
chr2_149410962_149411356	0.35	EPC2	enhancer of polycomb homolog 2 (Drosophila)	8170	0.31
chr19_16491335_16491486	0.35	ENSG00000243745	.	18360	0.13
chr12_107349023_107349234	0.35	RP11-412D9.4		147	0.76
chr13_21100202_21100498	0.35	CRYL1	crystallin, lambda 1	354	0.9
chr9_80558186_80558364	0.35	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	87245	0.1
chr3_128291882_128292072	0.35	C3orf27	chromosome 3 open reading frame 27	2952	0.28
chr7_5741379_5741530	0.35	RNF216-IT1	RNF216 intronic transcript 1 (non-protein coding)	21362	0.18
chr9_139298507_139298796	0.35	SDCCAG3	serologically defined colon cancer antigen 3	2986	0.14
chr19_6464851_6465002	0.35	SLC25A23	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23	288	0.54
chr2_240154622_240154773	0.34	HDAC4	histone deacetylase 4	41945	0.13
chr6_159516213_159516422	0.34	TAGAP	T-cell activation RhoGTPase activating protein	50133	0.12
chr6_119669203_119669435	0.34	MAN1A1	mannosidase, alpha, class 1A, member 1	1582	0.48
chr19_54703476_54703677	0.34	AC012314.20		262	0.74
chr4_15768464_15768936	0.34	CD38	CD38 molecule	11201	0.22
chr5_141302626_141302924	0.34	KIAA0141	KIAA0141	598	0.68
chr14_105258900_105259051	0.34	AKT1	v-akt murine thymoma viral oncogene homolog 1	1062	0.42
chr16_397961_398310	0.34	AXIN1	axin 1	4314	0.12
chr19_10624773_10624938	0.34	S1PR5	sphingosine-1-phosphate receptor 5	3248	0.12
chr1_53102699_53102972	0.34	FAM159A	family with sequence similarity 159, member A	3819	0.21
chrX_129313027_129313307	0.33	RAB33A	RAB33A, member RAS oncogene family	7544	0.2
chr12_56428109_56428367	0.33	RP11-603J24.4		7352	0.08
chr9_79792561_79792712	0.33	VPS13A	vacuolar protein sorting 13 homolog A (S. cerevisiae)	186	0.62
chr1_228058861_228059039	0.33	PRSS38	protease, serine, 38	55556	0.1
chr8_81059494_81059645	0.33	TPD52	tumor protein D52	23866	0.17
chr19_57947006_57947211	0.33	ZNF749	zinc finger protein 749	397	0.7
chr5_137089220_137089470	0.33	HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	694	0.72
chr11_6340807_6341145	0.33	PRKCDBP	protein kinase C, delta binding protein	786	0.59
chr15_29744792_29744981	0.33	FAM189A1	family with sequence similarity 189, member A1	117	0.98
chr19_58459238_58459526	0.33	ZNF256	zinc finger protein 256	339	0.79
chr15_99193368_99193519	0.33	IGF1R	insulin-like growth factor 1 receptor	1170	0.51
chr1_158260908_158261068	0.33	CD1C	CD1c molecule	72	0.97
chr9_96215108_96215362	0.33	FAM120A	family with sequence similarity 120A	569	0.45
chr1_218337416_218337567	0.32	ENSG00000201493	.	34354	0.22
chr12_57828360_57828511	0.32	INHBC	inhibin, beta C	108	0.92
chr17_18292327_18292514	0.32	RP1-37N7.1		122	0.94
chr13_39611171_39611519	0.32	PROSER1	proline and serine rich 1	629	0.61
chr2_3583541_3583693	0.32	RP13-512J5.1	Uncharacterized protein	11930	0.12
chr10_74855175_74855736	0.32	P4HA1	prolyl 4-hydroxylase, alpha polypeptide I	1153	0.34
chr15_32656988_32657139	0.32	ENSG00000221444	.	28610	0.11
chr12_56123322_56123555	0.32	CD63	CD63 molecule	6	0.88
chr5_35905050_35905201	0.32	IL7R	interleukin 7 receptor	29609	0.14
chr18_18684587_18684740	0.32	ROCK1	Rho-associated, coiled-coil containing protein kinase 1	7149	0.22
chr3_187646954_187647105	0.32	BCL6	B-cell CLL/lymphoma 6	183514	0.03
chr15_86162048_86162199	0.32	RP11-815J21.3		8797	0.15
chr15_48253421_48253572	0.32	SLC24A5	solute carrier family 24 (sodium/potassium/calcium exchanger), member 5	159673	0.03
chr20_61050006_61050157	0.31	GATA5	GATA binding protein 5	945	0.53
chr11_66648724_66648875	0.31	LRFN4	leucine rich repeat and fibronectin type III domain containing 4	23826	0.11
chr20_61926906_61927057	0.31	COL20A1	collagen, type XX, alpha 1	589	0.6
chr2_231922115_231922266	0.31	PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	582	0.69
chr1_202601340_202601491	0.31	SYT2	synaptotagmin II	11166	0.2
chrX_135698145_135698296	0.31	ENSG00000233093	.	23482	0.13
chr8_2048608_2048759	0.31	MYOM2	myomesin 2	55499	0.16
chr9_95796248_95796411	0.31	FGD3	FYVE, RhoGEF and PH domain containing 3	18987	0.17
chr14_91252167_91252318	0.31	TTC7B	tetratricopeptide repeat domain 7B	339	0.92
chr8_128749459_128749814	0.31	MYC	v-myc avian myelocytomatosis viral oncogene homolog	1159	0.61
chr19_50031302_50031619	0.31	RCN3	reticulocalbin 3, EF-hand calcium binding domain	87	0.9
chr11_2580790_2581027	0.31	KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	97791	0.06
chr1_42139980_42140148	0.31	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	26608	0.23
chr1_9742854_9743135	0.31	RP11-558F24.4		4619	0.2
chr16_29612414_29612565	0.31	ENSG00000266758	.	1903	0.28
chr2_157179145_157179330	0.30	NR4A2	nuclear receptor subfamily 4, group A, member 2	7396	0.28
chr4_1210952_1211162	0.30	CTBP1	C-terminal binding protein 1	2807	0.19
chr11_72902349_72902500	0.30	RP11-800A3.2		24534	0.14
chr22_23519705_23519942	0.30	BCR	breakpoint cluster region	2574	0.21
chr8_56903572_56903811	0.30	ENSG00000240905	.	10595	0.16
chr1_143672947_143673098	0.30	ENSG00000238825	.	268	0.88
chr15_55700873_55701267	0.30	C15orf65	chromosome 15 open reading frame 65	324	0.51
chr21_33857337_33857488	0.30	ENSG00000252045	.	53197	0.09
chr6_144607266_144607540	0.30	UTRN	utrophin	566	0.83
chr19_7969209_7969360	0.30	MAP2K7	mitogen-activated protein kinase kinase 7	508	0.43
chr1_21909962_21910113	0.30	RP11-63N8.3		2928	0.22
chr21_46335607_46335822	0.30	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	1516	0.25
chr11_118269921_118270178	0.29	ATP5L	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G	1820	0.19
chr14_22985817_22985968	0.29	TRAJ15	T cell receptor alpha joining 15	12688	0.1
chr7_157461175_157461436	0.29	AC005481.5	Uncharacterized protein	54590	0.13
chr10_14769257_14769408	0.29	FAM107B	family with sequence similarity 107, member B	47564	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.4	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.1	0.4	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	0.4	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	0.3	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.2	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1	0.2	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	0.5	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.1	0.3	GO:0071699	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.2	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.2	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.1	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.1	0.3	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.1	0.2	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	0.1	GO:0046877	regulation of saliva secretion(GO:0046877)
0.1	0.2	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.1	0.3	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	0.2	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.2	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.3	GO:0034695	response to prostaglandin E(GO:0034695)
0.1	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.3	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.2	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.4	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.3	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.2	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.4	GO:0009650	UV protection(GO:0009650)
0.0	0.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.2	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.0	GO:0032816	positive regulation of natural killer cell activation(GO:0032816)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.1	GO:0045425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0	0.4	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.2	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.6	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.1	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.2	GO:0045116	protein neddylation(GO:0045116)
0.0	0.6	GO:0032648	regulation of interferon-beta production(GO:0032648)
0.0	0.3	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.0	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.3	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.2	GO:0014009	glial cell proliferation(GO:0014009)
0.0	0.1	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.2	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.3	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.0	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.2	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.1	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:2000351	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.2	GO:0075713	establishment of viral latency(GO:0019043) establishment of integrated proviral latency(GO:0075713)
0.0	0.0	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.2	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.2	GO:0006896	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.3	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.2	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.1	GO:0016233	telomere capping(GO:0016233) protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.0	GO:0071221	response to bacterial lipoprotein(GO:0032493) detection of bacterial lipoprotein(GO:0042494) response to bacterial lipopeptide(GO:0070339) detection of bacterial lipopeptide(GO:0070340) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0	0.0	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.4	GO:0046834	lipid phosphorylation(GO:0046834)
0.0	0.3	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.4	GO:0032729	positive regulation of interferon-gamma production(GO:0032729)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.0	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0031342	negative regulation of leukocyte mediated cytotoxicity(GO:0001911) negative regulation of cell killing(GO:0031342)
0.0	0.1	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.2	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0048541	Peyer's patch development(GO:0048541)
0.0	0.2	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.0	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.2	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.1	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.1	GO:0060406	positive regulation of penile erection(GO:0060406)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.0	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0060438	trachea development(GO:0060438)
0.0	0.2	GO:1902591	vesicle coating(GO:0006901) single-organism membrane budding(GO:1902591)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.4	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.0	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.4	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	0.0	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.3	GO:0044766	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.2	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.0	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.0	GO:0072179	nephric duct formation(GO:0072179)
0.0	0.1	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.1	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.0	0.1	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.3	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.2	GO:0006906	vesicle fusion(GO:0006906)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.1	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0098927	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.0	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.0	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.0	GO:0070972	protein targeting to ER(GO:0045047) protein localization to endoplasmic reticulum(GO:0070972) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.1	GO:0002090	regulation of receptor internalization(GO:0002090)
0.0	0.1	GO:0010155	regulation of proton transport(GO:0010155)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.0	GO:0021853	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.0	GO:0030540	female genitalia development(GO:0030540)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0051798	positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0	0.0	GO:0040034	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0	0.0	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.2	GO:1905037	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.0	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
0.0	0.1	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.0	GO:0002251	organ or tissue specific immune response(GO:0002251)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.0	GO:0060405	regulation of penile erection(GO:0060405)
0.0	0.0	GO:0051014	actin filament severing(GO:0051014)
0.0	0.8	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.0	GO:0061028	establishment of endothelial barrier(GO:0061028)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:1901503	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.0	GO:0001845	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.1	GO:0009744	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0	0.0	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.0	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.0	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.1	GO:0007032	endosome organization(GO:0007032)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.0	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.0	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.0	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.0	GO:0010829	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.0	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.0	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.0	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.3	GO:0009311	oligosaccharide metabolic process(GO:0009311)
0.0	0.0	GO:0001878	response to yeast(GO:0001878)
0.0	0.0	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.1	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.0	GO:0014044	Schwann cell development(GO:0014044)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.2	GO:0051899	membrane depolarization(GO:0051899)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0033504	floor plate development(GO:0033504)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.0	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.2	GO:0006306	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.0	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.2	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.5	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.0	0.0	GO:0032481	positive regulation of type I interferon production(GO:0032481)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.0	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.7	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.5	GO:0008360	regulation of cell shape(GO:0008360)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.1	0.4	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1	0.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.4	GO:0032059	bleb(GO:0032059)
0.1	0.4	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.2	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.4	GO:0005682	U5 snRNP(GO:0005682)
0.1	0.4	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.2	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0000791	euchromatin(GO:0000791)
0.0	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.4	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312) external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.2	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.3	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.0	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.3	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.3	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.5	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.9	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.1	GO:0031672	A band(GO:0031672)
0.0	0.0	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.2	GO:0032982	myosin filament(GO:0032982)
0.0	0.0	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.2	GO:0005776	autophagosome(GO:0005776)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.2	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.0	GO:0001939	female pronucleus(GO:0001939)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.4	GO:0004875	complement receptor activity(GO:0004875)
0.1	0.3	GO:0071723	lipopeptide binding(GO:0071723)
0.1	0.2	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1	0.2	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.2	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1	0.3	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	0.3	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.1	0.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.2	GO:0004340	glucokinase activity(GO:0004340)
0.1	0.4	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	0.2	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.3	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.5	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.2	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.8	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.1	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.4	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0	0.3	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.2	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0043047	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.5	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.2	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.2	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.2	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.3	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.0	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.4	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	0.2	GO:0005537	mannose binding(GO:0005537)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.0	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.0	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.0	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.0	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.0	GO:0070513	death domain binding(GO:0070513)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.0	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0030553	cGMP binding(GO:0030553)
0.0	0.0	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.0	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.0	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.4	GO:0001948	glycoprotein binding(GO:0001948)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.3	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.0	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.0	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.2	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.4	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.8	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.3	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.7	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.2	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.6	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1	PID TNF PATHWAY	TNF receptor signaling pathway
0.3	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.4	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.4	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	PID IL12 2PATHWAY	IL12-mediated signaling events
0.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.4	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	ST GAQ PATHWAY	G alpha q Pathway
0.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	PID IFNG PATHWAY	IFN-gamma pathway
0.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	PID EPO PATHWAY	EPO signaling pathway
0.5	PID NOTCH PATHWAY	Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.7	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.4	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.4	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.4	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.6	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.0	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.5	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.9	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.4	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.5	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.9	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.0	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events

Results for XBP1

Z-value: 1.90

Motif logo

Transcription factors associated with XBP1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the XBP1 motif across conditions

Conditions sorted by the z-value of the XBP1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of XBP1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: