Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for YY1_YY2

Z-value: 3.09

Motif logo

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Transcription factors associated with YY1_YY2

Gene Symbol Gene ID Gene Info
ENSG00000100811.6 YY1
ENSG00000230797.2 YY2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
YY1chr14_100679445_100679678250740.1023770.924.4e-04Click!
YY1chr14_100690963_100691215135460.1127580.908.9e-04Click!
YY1chr14_100681152_100681494233120.1042760.862.7e-03Click!
YY1chr14_100703913_1007040976300.4608410.862.7e-03Click!
YY1chr14_100703452_10070381910000.3303720.862.8e-03Click!

Activity of the YY1_YY2 motif across conditions

Conditions sorted by the z-value of the YY1_YY2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_151131154_151131481 1.55 SCNM1
sodium channel modifier 1
2177
0.13
chr17_72736547_72736875 1.42 RAB37
RAB37, member RAS oncogene family
3340
0.13
chr7_38392883_38393137 1.06 AMPH
amphiphysin
109703
0.07
chr3_186502213_186502364 1.05 EIF4A2
eukaryotic translation initiation factor 4A2
296
0.31
chr3_47031300_47031468 1.02 NBEAL2
neurobeachin-like 2
5427
0.19
chr2_10518114_10518365 0.94 HPCAL1
hippocalcin-like 1
41908
0.14
chr1_31223610_31223819 0.91 LAPTM5
lysosomal protein transmembrane 5
6953
0.17
chr8_61912101_61912451 0.89 CLVS1
clavesin 1
57441
0.16
chr1_40529943_40530230 0.89 PPT1
palmitoyl-protein thioesterase 1
17907
0.17
chr1_169014315_169014663 0.89 ENSG00000252987
.
22013
0.19
chr17_76706821_76706987 0.88 CYTH1
cytohesin 1
6203
0.21
chr12_68024056_68024581 0.87 DYRK2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
17800
0.25
chr1_112012627_112013001 0.87 C1orf162
chromosome 1 open reading frame 162
3600
0.12
chr2_106416064_106416453 0.83 NCK2
NCK adaptor protein 2
16757
0.26
chr4_122744076_122744227 0.83 CCNA2
cyclin A2
936
0.53
chr6_144679009_144679160 0.82 UTRN
utrophin
13847
0.24
chr16_29612175_29612326 0.79 ENSG00000266758
.
1664
0.31
chr1_175157259_175157701 0.78 KIAA0040
KIAA0040
4410
0.3
chr19_16677261_16677463 0.78 CTD-3222D19.10

1000
0.33
chr1_117283826_117284150 0.77 CD2
CD2 molecule
13019
0.2
chr12_66553365_66553640 0.77 TMBIM4
transmembrane BAX inhibitor motif containing 4
9789
0.16
chr22_24835789_24836171 0.77 ADORA2A
adenosine A2a receptor
7172
0.18
chr17_61774575_61774907 0.77 LIMD2
LIM domain containing 2
1781
0.29
chr3_196351016_196351281 0.76 LINC01063
long intergenic non-protein coding RNA 1063
8310
0.13
chr10_103594369_103594974 0.75 KCNIP2
Kv channel interacting protein 2
4476
0.17
chr19_51875219_51875428 0.75 NKG7
natural killer cell group 7 sequence
334
0.7
chr10_81009151_81009302 0.74 ZMIZ1
zinc finger, MIZ-type containing 1
56749
0.14
chr18_48698507_48698802 0.74 MEX3C
mex-3 RNA binding family member C
24475
0.22
chr3_186743031_186743182 0.74 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
161
0.97
chr7_2551576_2551773 0.73 LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
489
0.77
chr7_144508892_144509461 0.72 TPK1
thiamin pyrophosphokinase 1
23970
0.23
chr20_47334657_47334897 0.71 ENSG00000251876
.
21208
0.26
chr16_17164092_17164271 0.71 CTD-2576D5.4

64180
0.15
chr11_67178315_67178466 0.71 CARNS1
carnosine synthase 1
4759
0.07
chr16_57074470_57074640 0.71 NLRC5
NLR family, CARD domain containing 5
13764
0.13
chr20_61435133_61435481 0.70 OGFR
opioid growth factor receptor
880
0.4
chr2_69004064_69004400 0.69 ARHGAP25
Rho GTPase activating protein 25
2160
0.38
chrX_48792186_48792645 0.68 PIM2
pim-2 oncogene
16114
0.08
chr18_29622386_29622822 0.68 ENSG00000265063
.
18348
0.13
chr15_72658157_72658434 0.68 HEXA
hexosaminidase A (alpha polypeptide)
9890
0.15
chr11_67414492_67414700 0.68 ACY3
aspartoacylase (aminocyclase) 3
458
0.69
chr10_22611140_22611362 0.67 BMI1
BMI1 polycomb ring finger oncogene
216
0.91
chr22_19103707_19103876 0.67 AC004471.9

5251
0.12
chr7_50416211_50416637 0.67 IKZF1
IKAROS family zinc finger 1 (Ikaros)
49179
0.16
chr9_134851506_134851657 0.67 MED27
mediator complex subunit 27
103672
0.07
chr1_90460180_90460445 0.66 ZNF326
zinc finger protein 326
362
0.9
chr7_76869055_76869341 0.66 AC073635.5

18242
0.2
chr3_127842145_127842409 0.65 RUVBL1
RuvB-like AAA ATPase 1
366
0.84
chr3_170897594_170897781 0.65 TNIK
TRAF2 and NCK interacting kinase
45813
0.17
chr1_207080791_207081015 0.65 IL24
interleukin 24
9725
0.14
chr2_85767177_85767896 0.64 MAT2A
methionine adenosyltransferase II, alpha
771
0.45
chr3_194025518_194025714 0.64 CPN2
carboxypeptidase N, polypeptide 2
46431
0.14
chr2_106701408_106701559 0.63 C2orf40
chromosome 2 open reading frame 40
19227
0.23
chr17_37049047_37049226 0.63 RP1-56K13.2

11717
0.1
chr14_90188252_90188490 0.63 ENSG00000200312
.
9516
0.23
chr21_36401379_36401530 0.63 RUNX1
runt-related transcription factor 1
20008
0.29
chrX_131119863_131120181 0.63 ENSG00000265686
.
10851
0.22
chr5_169704297_169704473 0.63 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
10054
0.22
chr10_126368794_126368955 0.62 FAM53B-AS1
FAM53B antisense RNA 1
23320
0.19
chr12_56040396_56040725 0.62 OR10P1
olfactory receptor, family 10, subfamily P, member 1
9916
0.1
chr14_68162102_68162376 0.61 RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
208
0.88
chr18_14132121_14132353 0.61 ZNF519
zinc finger protein 519
190
0.93
chr2_233943754_233943945 0.61 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
18660
0.18
chr10_11224652_11224918 0.61 RP3-323N1.2

11446
0.22
chr16_28995183_28995334 0.61 LAT
linker for activation of T cells
889
0.35
chr10_11287980_11288168 0.61 CELF2-AS1
CELF2 antisense RNA 1
73773
0.1
chr6_41991434_41991643 0.60 ENSG00000206875
.
5286
0.18
chr17_76411281_76411451 0.60 AC061992.1
Uncharacterized protein
11043
0.13
chr19_36100517_36101264 0.60 HAUS5
HAUS augmin-like complex, subunit 5
2782
0.13
chr3_47029046_47029197 0.60 CCDC12
coiled-coil domain containing 12
5649
0.19
chr6_33775484_33775750 0.60 MLN
motilin
3829
0.22
chrX_102470754_102470990 0.59 BEX4
brain expressed, X-linked 4
820
0.61
chr5_171611435_171611646 0.59 STK10
serine/threonine kinase 10
3850
0.23
chr2_158296763_158296940 0.59 CYTIP
cytohesin 1 interacting protein
925
0.48
chrX_48796338_48796526 0.59 OTUD5
OTU domain containing 5
18019
0.08
chr10_103893451_103893602 0.58 PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
729
0.58
chr4_53525238_53525389 0.58 USP46
ubiquitin specific peptidase 46
144
0.96
chr1_160606881_160607032 0.58 SLAMF1
signaling lymphocytic activation molecule family member 1
9855
0.16
chr10_11270548_11270811 0.57 RP3-323N1.2

57340
0.13
chr21_42735504_42736074 0.57 MX2
myxovirus (influenza virus) resistance 2 (mouse)
1855
0.36
chr11_3846573_3846831 0.56 RHOG
ras homolog family member G
5179
0.11
chr20_39787532_39787703 0.56 RP1-1J6.2

20974
0.18
chr1_65357847_65358013 0.56 JAK1
Janus kinase 1
74257
0.11
chr17_7236874_7237266 0.56 ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
2778
0.09
chrX_135230186_135230374 0.56 FHL1
four and a half LIM domains 1
10
0.98
chr3_196361781_196362314 0.56 LINC01063
long intergenic non-protein coding RNA 1063
2589
0.19
chr3_127348995_127349623 0.56 PODXL2
podocalyxin-like 2
1285
0.41
chr18_48722213_48722555 0.55 MEX3C
mex-3 RNA binding family member C
745
0.76
chr7_38328753_38328904 0.55 STARD3NL
STARD3 N-terminal like
110831
0.07
chr1_47692342_47692583 0.55 RP1-18D14.7

993
0.47
chr7_38401901_38402261 0.54 AMPH
amphiphysin
100632
0.08
chr6_3003368_3003519 0.54 NQO2
NAD(P)H dehydrogenase, quinone 2
958
0.46
chr7_127669033_127669184 0.54 LRRC4
leucine rich repeat containing 4
1950
0.41
chr11_121328693_121328910 0.54 RP11-730K11.1

5079
0.26
chr12_48136274_48136430 0.54 SLC48A1
solute carrier family 48 (heme transporter), member 1
11347
0.14
chr11_128574625_128574821 0.54 SENCR
smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
8805
0.19
chr19_2628984_2629135 0.54 CTC-265F19.3

2893
0.19
chr9_139424741_139425003 0.54 ENSG00000263403
.
10794
0.09
chr16_28172609_28172760 0.54 XPO6
exportin 6
8538
0.18
chr12_7060138_7060323 0.54 PTPN6
protein tyrosine phosphatase, non-receptor type 6
195
0.81
chr3_17045733_17045884 0.53 PLCL2
phospholipase C-like 2
6178
0.26
chr5_79032970_79033121 0.53 CMYA5
cardiomyopathy associated 5
47345
0.16
chr15_59397716_59397952 0.53 CCNB2
cyclin B2
478
0.74
chrX_128913033_128913442 0.53 SASH3
SAM and SH3 domain containing 3
723
0.69
chr10_74927104_74927421 0.53 ECD
ecdysoneless homolog (Drosophila)
555
0.45
chr18_74811464_74812005 0.53 MBP
myelin basic protein
5483
0.32
chr4_100815074_100815278 0.53 LAMTOR3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
357
0.89
chr3_187718435_187718739 0.53 LPP
LIM domain containing preferred translocation partner in lipoma
152485
0.04
chr1_22383731_22383923 0.53 CDC42-IT1
CDC42 intronic transcript 1 (non-protein coding)
1863
0.24
chr9_71611720_71611963 0.53 PRKACG
protein kinase, cAMP-dependent, catalytic, gamma
17198
0.21
chr5_169727089_169727317 0.53 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
1972
0.37
chr2_65658480_65658678 0.53 SPRED2
sprouty-related, EVH1 domain containing 2
732
0.75
chr19_44280688_44280980 0.53 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
4575
0.15
chr5_98105054_98105343 0.53 RGMB
repulsive guidance molecule family member b
199
0.95
chr22_30565603_30565778 0.52 RP3-438O4.4

37408
0.11
chr17_72457353_72457898 0.52 CD300A
CD300a molecule
4930
0.16
chr17_62031586_62031902 0.52 SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
18534
0.1
chr22_40698854_40699005 0.52 TNRC6B
trinucleotide repeat containing 6B
37922
0.14
chr11_95988623_95988872 0.52 ENSG00000266192
.
85855
0.09
chr1_26646643_26646990 0.52 UBXN11
UBX domain protein 11
1962
0.19
chr1_206740944_206741168 0.52 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
10563
0.16
chr7_1551615_1551787 0.52 AC102953.6

2638
0.2
chr22_50050308_50050574 0.51 C22orf34
chromosome 22 open reading frame 34
637
0.74
chr11_73724919_73725168 0.51 UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
4563
0.18
chr7_143107156_143107361 0.51 EPHA1
EPH receptor A1
1273
0.3
chr19_16188882_16189115 0.51 TPM4
tropomyosin 4
1167
0.45
chr16_67836925_67837076 0.51 RANBP10
RAN binding protein 10
3460
0.13
chr5_80052245_80052416 0.51 DHFR
dihydrofolate reductase
101528
0.06
chr11_128421120_128421411 0.51 RP11-1007G5.2

25228
0.2
chr3_30685597_30685782 0.51 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
37596
0.2
chr8_27187954_27188105 0.51 PTK2B
protein tyrosine kinase 2 beta
3689
0.25
chr8_61798114_61798398 0.51 RP11-33I11.2

76091
0.12
chr7_73630981_73631230 0.51 LAT2
linker for activation of T cells family, member 2
6752
0.16
chr4_775014_775218 0.51 RP11-440L14.1

502
0.7
chr11_57440583_57440734 0.50 ZDHHC5
zinc finger, DHHC-type containing 5
42
0.95
chr6_25127946_25128097 0.50 ENSG00000222373
.
64620
0.09
chr12_12618425_12618997 0.50 DUSP16
dual specificity phosphatase 16
55348
0.13
chr16_68109101_68109477 0.50 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
9958
0.1
chr1_1809985_1810136 0.50 GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
11780
0.13
chr3_4887253_4887670 0.50 ENSG00000239126
.
32925
0.17
chr21_43656564_43656905 0.50 ENSG00000223262
.
15451
0.16
chr16_67280838_67280991 0.50 SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
96
0.86
chrX_13106186_13106576 0.50 FAM9C
family with sequence similarity 9, member C
43580
0.18
chr5_156695794_156695989 0.50 CYFIP2
cytoplasmic FMR1 interacting protein 2
471
0.73
chr5_32211061_32211425 0.49 ENSG00000199731
.
23738
0.17
chr1_65341561_65341911 0.49 JAK1
Janus kinase 1
90451
0.08
chr21_34757403_34757693 0.49 IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
17654
0.17
chr5_170814436_170814587 0.49 NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
141
0.89
chr1_244614751_244614902 0.49 ADSS
adenylosuccinate synthase
610
0.75
chr5_142178965_142179116 0.49 ARHGAP26
Rho GTPase activating protein 26
26758
0.22
chr16_30915705_30915976 0.48 CTF1
cardiotrophin 1
7881
0.08
chr17_56456680_56457108 0.48 RNF43
ring finger protein 43
23188
0.11
chr19_16475924_16476075 0.48 EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
3235
0.2
chr14_102187835_102187986 0.48 RP11-796G6.2
Uncharacterized protein
8864
0.2
chr12_32108406_32108639 0.48 KIAA1551
KIAA1551
3820
0.28
chr15_22541633_22541784 0.48 ENSG00000221641
.
28428
0.14
chr20_44632330_44632481 0.48 MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
5142
0.14
chr19_14227765_14227948 0.48 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
688
0.47
chr9_117214736_117215110 0.48 DFNB31
deafness, autosomal recessive 31
26572
0.19
chr2_73180819_73181067 0.48 EMX1
empty spiracles homeobox 1
29826
0.19
chr18_13455865_13456016 0.47 ENSG00000266146
.
4006
0.13
chr2_198056440_198057324 0.47 ANKRD44
ankyrin repeat domain 44
5049
0.23
chr5_171710215_171710366 0.47 UBTD2
ubiquitin domain containing 2
785
0.61
chr12_32044487_32044661 0.47 ENSG00000252584
.
24067
0.19
chr11_118110321_118110509 0.47 MPZL3
myelin protein zero-like 3
12647
0.13
chr9_126078171_126078322 0.47 CRB2
crumbs homolog 2 (Drosophila)
40203
0.16
chr10_126396441_126396724 0.47 FAM53B-AS1
FAM53B antisense RNA 1
3829
0.24
chr9_117133277_117133577 0.47 AKNA
AT-hook transcription factor
5817
0.21
chr2_65258054_65258356 0.47 AC007386.4

6426
0.18
chr16_23879975_23880302 0.47 PRKCB
protein kinase C, beta
31594
0.2
chr1_167481938_167482089 0.47 CD247
CD247 molecule
5762
0.22
chr5_130673905_130674056 0.47 CDC42SE2
CDC42 small effector 2
47319
0.19
chr3_172229552_172229796 0.46 TNFSF10
tumor necrosis factor (ligand) superfamily, member 10
11591
0.24
chr5_148928879_148929268 0.46 CSNK1A1
casein kinase 1, alpha 1
789
0.57
chr1_40861758_40861909 0.46 SMAP2
small ArfGAP2
674
0.68
chr8_96225080_96225231 0.46 C8orf37
chromosome 8 open reading frame 37
56274
0.13
chr11_117870973_117871190 0.46 IL10RA
interleukin 10 receptor, alpha
13972
0.18
chr2_70270796_70271043 0.46 PCBP1-AS1
PCBP1 antisense RNA 1
9998
0.17
chrX_2526583_2526783 0.46 CD99P1
CD99 molecule pseudogene 1
773
0.73
chr15_70007265_70007861 0.46 ENSG00000238870
.
15598
0.26
chr3_13111271_13111777 0.46 IQSEC1
IQ motif and Sec7 domain 1
3093
0.38
chr19_7416022_7416191 0.46 CTB-133G6.1

2258
0.25
chr17_40424448_40424646 0.46 AC003104.1

154
0.92
chr13_99931097_99931381 0.46 GPR18
G protein-coupled receptor 18
17241
0.18
chr2_101734457_101734660 0.46 ENSG00000265860
.
24527
0.18
chrX_70922556_70922717 0.46 ENSG00000221684
.
56669
0.12
chr19_41812316_41812501 0.45 CCDC97
coiled-coil domain containing 97
3686
0.14
chr16_378752_379023 0.45 AXIN1
axin 1
23562
0.09
chr22_30660984_30661135 0.45 OSM
oncostatin M
748
0.48
chr11_72864714_72865145 0.45 FCHSD2
FCH and double SH3 domains 2
11623
0.2
chr7_132338688_132338846 0.45 AC009365.3

5214
0.24
chr8_19553038_19553384 0.45 CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
12939
0.29
chr3_9821453_9821979 0.45 CAMK1
calcium/calmodulin-dependent protein kinase I
10040
0.09
chr1_27959576_27959857 0.45 FGR
feline Gardner-Rasheed sarcoma viral oncogene homolog
2011
0.24
chr17_8858889_8859261 0.45 PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
9949
0.24
chr10_103348067_103348273 0.45 DPCD
deleted in primary ciliary dyskinesia homolog (mouse)
81
0.59
chr7_150148117_150148329 0.45 GIMAP8
GTPase, IMAP family member 8
505
0.77
chr17_55638467_55638714 0.45 RP11-118E18.2

37632
0.15
chr1_203290311_203290744 0.45 ENSG00000202300
.
2300
0.27
chr14_71123170_71123492 0.45 TTC9
tetratricopeptide repeat domain 9
14827
0.21

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of YY1_YY2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.3 0.8 GO:0030223 neutrophil differentiation(GO:0030223)
0.2 1.7 GO:0007172 signal complex assembly(GO:0007172)
0.2 0.8 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.2 1.0 GO:0007386 compartment pattern specification(GO:0007386)
0.2 0.5 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 0.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.3 GO:0019042 viral latency(GO:0019042)
0.2 0.8 GO:0045059 positive thymic T cell selection(GO:0045059)
0.2 0.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 0.6 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.2 0.5 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.7 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 0.6 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.1 0.4 GO:0014056 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1 0.9 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.5 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 0.3 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.4 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.5 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.2 GO:0006154 adenosine catabolic process(GO:0006154)
0.1 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.1 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.1 0.4 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.3 GO:0060242 contact inhibition(GO:0060242)
0.1 0.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.5 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.6 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.1 GO:0002448 mast cell mediated immunity(GO:0002448)
0.1 0.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.3 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.5 GO:0046645 regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.1 0.1 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.1 0.3 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.3 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.1 0.3 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 1.7 GO:0046834 lipid phosphorylation(GO:0046834)
0.1 0.3 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.2 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 2.2 GO:0045576 mast cell activation(GO:0045576)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.2 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.7 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.1 0.1 GO:0002507 tolerance induction(GO:0002507)
0.1 0.2 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.1 0.5 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772)
0.1 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.2 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.6 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.1 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.1 0.3 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.1 0.2 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.7 GO:0040023 establishment of nucleus localization(GO:0040023)
0.1 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.0 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.3 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.4 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.2 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.1 0.2 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.6 GO:0002063 chondrocyte development(GO:0002063)
0.1 0.2 GO:0007035 vacuolar acidification(GO:0007035)
0.1 0.1 GO:0034143 regulation of toll-like receptor 3 signaling pathway(GO:0034139) regulation of toll-like receptor 4 signaling pathway(GO:0034143) positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.3 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.5 GO:0006547 histidine metabolic process(GO:0006547)
0.1 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.3 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.2 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.1 GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
0.1 0.3 GO:0090224 regulation of spindle organization(GO:0090224)
0.1 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.1 0.2 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.1 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.1 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1 0.1 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.8 GO:0000303 response to superoxide(GO:0000303)
0.1 0.1 GO:0043300 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) regulation of leukocyte degranulation(GO:0043300) negative regulation of leukocyte degranulation(GO:0043301)
0.1 0.5 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.1 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1 1.8 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.1 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 1.2 GO:0045730 respiratory burst(GO:0045730)
0.1 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 0.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 0.1 GO:0034122 negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.1 1.3 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.1 0.3 GO:0051642 centrosome localization(GO:0051642)
0.1 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.1 GO:0009414 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1 0.6 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.1 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.1 GO:0002645 regulation of tolerance induction(GO:0002643) positive regulation of tolerance induction(GO:0002645)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.1 GO:0016445 somatic diversification of immunoglobulins(GO:0016445)
0.1 0.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0045056 transcytosis(GO:0045056)
0.1 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.1 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.4 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.1 GO:0043049 otic placode formation(GO:0043049)
0.1 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.1 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.1 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.1 0.2 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.2 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.1 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.1 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.1 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.0 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.2 GO:0003093 regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.1 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1 0.1 GO:0015809 arginine transport(GO:0015809)
0.1 0.3 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.1 0.3 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.1 GO:0060992 response to fungicide(GO:0060992)
0.1 0.2 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.1 0.3 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.1 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.2 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.1 0.1 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.1 0.2 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.2 GO:0000966 RNA 5'-end processing(GO:0000966)
0.1 0.4 GO:0006105 succinate metabolic process(GO:0006105)
0.1 0.2 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.1 0.4 GO:0050957 equilibrioception(GO:0050957)
0.1 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.8 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.2 GO:0031065 regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.1 0.3 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.1 0.2 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.1 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.2 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.1 0.2 GO:0033197 response to vitamin E(GO:0033197)
0.1 0.1 GO:2001259 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.1 0.4 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.5 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.1 0.1 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.1 GO:0006007 glucose catabolic process(GO:0006007)
0.1 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.2 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.2 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.3 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.0 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.2 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:0042754 negative regulation of circadian sleep/wake cycle, sleep(GO:0042321) negative regulation of circadian rhythm(GO:0042754) negative regulation of behavior(GO:0048521)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0010536 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.0 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0046794 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.8 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:2001021 negative regulation of response to DNA damage stimulus(GO:2001021)
0.0 0.2 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0032747 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.4 GO:0072599 protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0 0.6 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.2 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0032715 negative regulation of interleukin-6 production(GO:0032715)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.2 GO:1903313 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.5 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0002320 lymphoid progenitor cell differentiation(GO:0002320)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0032735 positive regulation of interleukin-12 production(GO:0032735)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0015904 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.2 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.2 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.3 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.0 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.3 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.3 GO:0001881 receptor recycling(GO:0001881)
0.0 0.2 GO:0031017 exocrine pancreas development(GO:0031017)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.0 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0 0.1 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.0 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0 2.7 GO:0050851 antigen receptor-mediated signaling pathway(GO:0050851)
0.0 0.1 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0048302 regulation of isotype switching to IgG isotypes(GO:0048302)
0.0 0.3 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 1.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.1 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.2 GO:0045980 negative regulation of nucleotide metabolic process(GO:0045980)
0.0 0.1 GO:0033158 regulation of protein import into nucleus, translocation(GO:0033158)
0.0 0.2 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.2 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.2 GO:0036465 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.3 GO:0001510 RNA methylation(GO:0001510)
0.0 0.0 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0048799 organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0 0.6 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.4 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.4 GO:0031648 protein destabilization(GO:0031648)
0.0 0.2 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:1901160 serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.2 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.7 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.3 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.4 GO:0007129 synapsis(GO:0007129) chromosome organization involved in meiotic cell cycle(GO:0070192)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.2 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.8 GO:1901185 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.2 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.1 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.0 GO:0090075 relaxation of muscle(GO:0090075)
0.0 0.2 GO:0016556 mRNA modification(GO:0016556)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.4 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.1 GO:0090192 regulation of glomerulus development(GO:0090192)
0.0 0.1 GO:0045123 cellular extravasation(GO:0045123)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.2 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.3 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.3 GO:0090174 organelle membrane fusion(GO:0090174)
0.0 0.2 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.9 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0042435 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) indole-containing compound biosynthetic process(GO:0042435)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.1 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.4 GO:1901661 quinone metabolic process(GO:1901661)
0.0 0.0 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0071674 mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0 0.4 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.7 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.1 GO:0045916 negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:0006266 DNA ligation(GO:0006266)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.1 GO:0044266 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0 0.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:0010288 response to lead ion(GO:0010288)
0.0 0.0 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.2 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.0 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.2 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.0 0.1 GO:0033087 regulation of immature T cell proliferation(GO:0033083) regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088) negative regulation of thymocyte aggregation(GO:2000399)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.0 GO:0071503 response to heparin(GO:0071503)
0.0 0.0 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.2 GO:0010039 response to iron ion(GO:0010039)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.0 GO:0051590 positive regulation of neurotransmitter transport(GO:0051590)
0.0 0.4 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.0 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0016045 detection of bacterium(GO:0016045)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0046006 regulation of activated T cell proliferation(GO:0046006)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.1 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.0 0.1 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:1903077 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.1 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.2 GO:1903578 regulation of glycolytic process(GO:0006110) regulation of nucleoside metabolic process(GO:0009118) regulation of ATP metabolic process(GO:1903578)
0.0 0.1 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.2 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.1 GO:0006534 cysteine metabolic process(GO:0006534)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.2 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.0 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.0 0.1 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.1 GO:0009804 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.0 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0 0.0 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.1 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.1 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 1.5 GO:0006959 humoral immune response(GO:0006959)
0.0 0.1 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0032459 regulation of protein oligomerization(GO:0032459)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0051647 nucleus localization(GO:0051647)
0.0 0.3 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0006997 nucleus organization(GO:0006997)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0007033 vacuole organization(GO:0007033)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.1 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.4 GO:0050832 defense response to fungus(GO:0050832)
0.0 1.2 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.2 GO:0046386 deoxyribose phosphate catabolic process(GO:0046386)
0.0 0.1 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0033363 secretory granule organization(GO:0033363)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0048536 spleen development(GO:0048536)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.2 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 1.5 GO:0006413 translational initiation(GO:0006413)
0.0 0.1 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.7 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.5 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.1 GO:0002286 T cell activation involved in immune response(GO:0002286)
0.0 0.3 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.1 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.1 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.2 GO:1903076 regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.0 GO:0071462 cellular response to water stimulus(GO:0071462)
0.0 0.2 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.4 GO:0051318 G1 phase(GO:0051318)
0.0 0.1 GO:1902743 regulation of lamellipodium organization(GO:1902743)
0.0 0.2 GO:0019724 B cell mediated immunity(GO:0019724)
0.0 0.0 GO:0031644 regulation of neurological system process(GO:0031644)
0.0 0.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.2 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.3 GO:0051607 defense response to virus(GO:0051607)
0.0 0.5 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 0.2 GO:0072595 maintenance of protein localization in organelle(GO:0072595)
0.0 0.0 GO:0042088 T-helper 1 type immune response(GO:0042088)
0.0 0.0 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.5 GO:0033572 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.2 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0 0.1 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.4 GO:0006885 regulation of pH(GO:0006885)
0.0 0.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.0 GO:0090266 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0006385 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.0 GO:0045006 DNA deamination(GO:0045006)
0.0 0.0 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.0 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.1 GO:0030851 granulocyte differentiation(GO:0030851)
0.0 0.1 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 1.2 GO:0008033 tRNA processing(GO:0008033)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0051882 mitochondrial depolarization(GO:0051882)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0044743 intracellular protein transmembrane import(GO:0044743) intracellular protein transmembrane transport(GO:0065002) protein transmembrane transport(GO:0071806)
0.0 0.4 GO:0043507 positive regulation of JUN kinase activity(GO:0043507)
0.0 0.1 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.0 GO:1902115 regulation of organelle assembly(GO:1902115) positive regulation of organelle assembly(GO:1902117)
0.0 0.4 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.0 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0014002 astrocyte development(GO:0014002)
0.0 0.2 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.0 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 4.3 GO:0006397 mRNA processing(GO:0006397)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0043586 tongue development(GO:0043586)
0.0 0.3 GO:0043486 histone exchange(GO:0043486)
0.0 0.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.0 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.2 GO:0001906 cell killing(GO:0001906)
0.0 0.0 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0006301 postreplication repair(GO:0006301)
0.0 0.1 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.4 GO:0006953 acute-phase response(GO:0006953)
0.0 0.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0051983 regulation of chromosome segregation(GO:0051983)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0045921 positive regulation of exocytosis(GO:0045921) positive regulation of calcium ion-dependent exocytosis(GO:0045956) positive regulation of regulated secretory pathway(GO:1903307)
0.0 0.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.0 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.0 GO:0051608 histamine transport(GO:0051608)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0042267 natural killer cell mediated immunity(GO:0002228) natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.0 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.5 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0045342 MHC class II biosynthetic process(GO:0045342)
0.0 0.2 GO:0044036 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.3 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439) positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.0 GO:0051972 regulation of telomerase activity(GO:0051972)
0.0 0.7 GO:0007498 mesoderm development(GO:0007498)
0.0 0.2 GO:0006595 polyamine metabolic process(GO:0006595)
0.0 0.0 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.0 GO:0002449 lymphocyte mediated immunity(GO:0002449)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0001662 behavioral fear response(GO:0001662)
0.0 0.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.7 GO:0072413 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in mitotic cell cycle checkpoint(GO:0072413) signal transduction involved in DNA damage checkpoint(GO:0072422) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) signal transduction involved in mitotic DNA damage checkpoint(GO:1902402) signal transduction involved in mitotic DNA integrity checkpoint(GO:1902403)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:1901224 activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0 0.0 GO:1903363 negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051) negative regulation of cellular protein catabolic process(GO:1903363)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0046039 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) GTP metabolic process(GO:0046039) UTP metabolic process(GO:0046051)
0.0 0.0 GO:0030147 obsolete natriuresis(GO:0030147)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.0 GO:0048247 lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0 0.0 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.0 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.0 0.0 GO:0071548 response to dexamethasone(GO:0071548)
0.0 0.0 GO:0034442 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.0 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.2 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.0 GO:0000239 pachytene(GO:0000239)
0.0 0.0 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.0 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.0 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.2 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.0 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.0 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.2 GO:0045930 negative regulation of mitotic cell cycle(GO:0045930)
0.0 0.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.0 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0000018 regulation of DNA recombination(GO:0000018)
0.0 0.0 GO:0044320 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.2 GO:0009988 binding of sperm to zona pellucida(GO:0007339) cell-cell recognition(GO:0009988) sperm-egg recognition(GO:0035036)
0.0 0.0 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.0 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0002329 immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0 0.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571) G1 DNA damage checkpoint(GO:0044783) mitotic G1/S transition checkpoint(GO:0044819) negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0031334 positive regulation of protein complex assembly(GO:0031334)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.0 GO:0032392 DNA geometric change(GO:0032392)
0.0 0.0 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0 0.0 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.0 GO:0015851 purine nucleobase transport(GO:0006863) nucleobase transport(GO:0015851) adenine transport(GO:0015853)
0.0 0.0 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0000216 obsolete M/G1 transition of mitotic cell cycle(GO:0000216)
0.0 0.0 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.2 GO:0019400 alditol metabolic process(GO:0019400)
0.0 0.3 GO:0006914 autophagy(GO:0006914)
0.0 0.0 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 1.0 GO:0050900 leukocyte migration(GO:0050900)
0.0 0.0 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.0 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.0 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.2 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.0 GO:0051769 nitric-oxide synthase biosynthetic process(GO:0051767) regulation of nitric-oxide synthase biosynthetic process(GO:0051769)
0.0 0.0 GO:0032908 transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908)
0.0 0.0 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.0 GO:0009309 amine biosynthetic process(GO:0009309)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0072162 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.4 GO:0007088 regulation of mitotic nuclear division(GO:0007088)
0.0 0.3 GO:0061025 membrane fusion(GO:0061025)
0.0 0.0 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.0 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:0010669 epithelial structure maintenance(GO:0010669) maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.0 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.3 GO:0007051 spindle organization(GO:0007051)
0.0 0.0 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.1 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0008380 RNA splicing(GO:0008380)
0.0 0.8 GO:0006364 rRNA processing(GO:0006364)
0.0 0.0 GO:0032770 positive regulation of monooxygenase activity(GO:0032770)
0.0 0.0 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.0 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.0 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.0 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418) amino acid activation(GO:0043038) tRNA aminoacylation(GO:0043039)
0.0 0.1 GO:0042113 B cell activation(GO:0042113)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.4 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.0 GO:0072193 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0043487 regulation of RNA stability(GO:0043487)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.0 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.0 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.0 1.1 GO:0030168 platelet activation(GO:0030168)
0.0 0.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.6 GO:0034248 regulation of translation(GO:0006417) regulation of cellular amide metabolic process(GO:0034248)
0.0 0.0 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.1 GO:0006069 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.0 GO:1903792 negative regulation of anion transport(GO:1903792)
0.0 0.0 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.2 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.6 GO:0071986 Ragulator complex(GO:0071986)
0.2 0.3 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0072487 MSL complex(GO:0072487)
0.1 0.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.5 GO:0005667 transcription factor complex(GO:0005667)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 0.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.3 GO:0001772 immunological synapse(GO:0001772)
0.1 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.7 GO:0000791 euchromatin(GO:0000791)
0.1 0.3 GO:0001940 male pronucleus(GO:0001940)
0.1 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.7 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.1 0.9 GO:0042101 T cell receptor complex(GO:0042101)
0.1 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.4 GO:0043218 compact myelin(GO:0043218)
0.1 0.6 GO:0005655 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1 0.1 GO:0030897 HOPS complex(GO:0030897)
0.1 0.2 GO:0000785 chromatin(GO:0000785)
0.1 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.6 GO:0070688 MLL5-L complex(GO:0070688)
0.1 0.3 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 1.5 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.5 GO:0031264 death-inducing signaling complex(GO:0031264)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.3 GO:0000800 lateral element(GO:0000800)
0.1 0.3 GO:0070552 BRISC complex(GO:0070552)
0.1 0.2 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0044462 external encapsulating structure part(GO:0044462)
0.1 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 2.0 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.1 0.2 GO:0001740 Barr body(GO:0001740)
0.1 0.6 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 2.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 0.2 GO:0042629 mast cell granule(GO:0042629)
0.1 1.1 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.4 GO:1904949 ATP-binding cassette (ABC) transporter complex(GO:0043190) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 0.1 GO:0042827 platelet dense granule(GO:0042827)
0.1 0.4 GO:0031094 platelet dense tubular network(GO:0031094)
0.1 0.2 GO:0070820 tertiary granule(GO:0070820)
0.1 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.6 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.4 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.8 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.4 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.7 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.4 GO:0034708 methyltransferase complex(GO:0034708) histone methyltransferase complex(GO:0035097)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0031082 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 1.2 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.5 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0031105 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.0 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 1.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 2.8 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.8 GO:0016604 nuclear body(GO:0016604)
0.0 0.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.5 GO:0005922 connexon complex(GO:0005922)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.0 GO:0005839 proteasome core complex(GO:0005839)
0.0 1.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.0 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510) clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 2.8 GO:0005819 spindle(GO:0005819)
0.0 0.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.6 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.0 GO:0045240 dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0 0.3 GO:0030139 endocytic vesicle(GO:0030139)
0.0 0.7 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.5 GO:0030175 filopodium(GO:0030175)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.0 GO:0033646 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.2 GO:0005694 chromosome(GO:0005694)
0.0 0.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.8 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0045179 apical cortex(GO:0045179)
0.0 1.4 GO:0005769 early endosome(GO:0005769)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 1.6 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0032155 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.0 GO:0042555 MCM complex(GO:0042555)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.8 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 1.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.2 GO:0045259 proton-transporting ATP synthase complex(GO:0045259)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.0 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0005775 vacuolar lumen(GO:0005775)
0.0 0.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0015935 small ribosomal subunit(GO:0015935)
0.0 0.4 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 10.0 GO:0005730 nucleolus(GO:0005730)
0.0 0.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.0 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.0 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 36.5 GO:0005634 nucleus(GO:0005634)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.0 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.0 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.0 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.3 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 0.9 GO:0042608 T cell receptor binding(GO:0042608)
0.2 0.7 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.2 0.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.2 1.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 0.6 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.2 1.0 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.2 0.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 0.5 GO:0031628 opioid receptor binding(GO:0031628)
0.2 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.7 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.7 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 1.6 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.1 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.1 0.4 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1 0.3 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 1.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.5 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.3 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.4 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.4 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.3 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.5 GO:0004568 chitinase activity(GO:0004568)
0.1 0.2 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.1 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.9 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.6 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.1 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.4 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.2 GO:0035197 siRNA binding(GO:0035197)
0.1 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.3 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 2.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.3 GO:0050733 RS domain binding(GO:0050733)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.5 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.2 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.1 0.4 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 2.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.5 GO:0030276 clathrin binding(GO:0030276)
0.1 0.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.1 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 0.1 GO:0042806 fucose binding(GO:0042806)
0.1 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.1 GO:0046790 virion binding(GO:0046790)
0.1 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.4 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 1.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.2 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.2 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
0.0 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.7 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0015205 nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.3 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.5 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.5 GO:0032451 demethylase activity(GO:0032451)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.9 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.9 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.6 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.2 GO:0022821 calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.5 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.3 GO:0060590 ATPase regulator activity(GO:0060590)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0015278 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.4 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.4 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.2 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.9 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.2 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.6 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.0 GO:0032182 ubiquitin-like protein binding(GO:0032182)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.8 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.0 GO:0016208 AMP binding(GO:0016208)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 1.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.5 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.0 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.9 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.0 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.0 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.7 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.0 0.1 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.3 GO:0000049 tRNA binding(GO:0000049)
0.0 0.7 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 9.9 GO:0003723 RNA binding(GO:0003723)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.7 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.0 GO:0019956 chemokine binding(GO:0019956)
0.0 0.3 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.3 GO:0004519 endonuclease activity(GO:0004519)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.2 GO:0051087 chaperone binding(GO:0051087)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0008066 glutamate receptor activity(GO:0008066)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.0 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.4 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.3 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 1.0 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.0 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0 0.0 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.3 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.0 0.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.0 GO:0015421 oligopeptide-transporting ATPase activity(GO:0015421)
0.0 0.0 GO:0016715 dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.0 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.0 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.2 GO:0008483 transaminase activity(GO:0008483)
0.0 0.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0004835 tubulin-tyrosine ligase activity(GO:0004835)
0.0 0.1 GO:0051117 ATPase binding(GO:0051117)
0.0 0.0 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 18.0 GO:0003677 DNA binding(GO:0003677)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 1.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.0 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.0 GO:0030955 potassium ion binding(GO:0030955)
0.0 1.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 8.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 1.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 2.9 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.1 2.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 0.5 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 1.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.0 PID ARF 3PATHWAY Arf1 pathway
0.1 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.3 PID BCR 5PATHWAY BCR signaling pathway
0.1 2.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 0.8 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 0.4 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.0 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.8 PID E2F PATHWAY E2F transcription factor network
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.3 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.6 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.0 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.4 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 2.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.2 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 0.7 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 4.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 3.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.1 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 1.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.1 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.8 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 0.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.0 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.0 REACTOME M G1 TRANSITION Genes involved in M/G1 Transition
0.0 0.0 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 3.8 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0 0.7 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.4 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.3 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.8 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.2 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.0 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.8 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.0 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.0 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.9 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.0 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.3 REACTOME MEIOSIS Genes involved in Meiosis
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 4.6 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.7 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism