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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZBTB14

Z-value: 2.29

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Transcription factors associated with ZBTB14

Gene Symbol Gene ID Gene Info
ENSG00000198081.6 ZBTB14

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ZBTB14chr18_5296007_5296158430.9857480.958.9e-05Click!
ZBTB14chr18_5295798_52959491660.9712980.941.9e-04Click!
ZBTB14chr18_5296626_52968543120.9348320.826.9e-03Click!
ZBTB14chr18_5294570_52947211780.9690510.452.2e-01Click!
ZBTB14chr18_5288553_528870461950.292336-0.373.2e-01Click!

Activity of the ZBTB14 motif across conditions

Conditions sorted by the z-value of the ZBTB14 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr15_73344221_73344400 1.41 NEO1
neogenin 1
259
0.96
chr8_21966484_21966635 0.97 NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
351
0.79
chr7_155088808_155089052 0.89 INSIG1
insulin induced gene 1
556
0.8
chr11_66384282_66384433 0.79 RBM14
RNA binding motif protein 14
171
0.41
chr14_23426380_23426575 0.77 HAUS4
HAUS augmin-like complex, subunit 4
107
0.66
chr19_49339202_49339632 0.74 HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
337
0.76
chr4_24474546_24474697 0.73 ENSG00000265001
.
43166
0.14
chr22_41681891_41682042 0.72 RANGAP1
Ran GTPase activating protein 1
3
0.96
chr5_180616538_180616689 0.71 CTC-338M12.5

2311
0.14
chr7_45960569_45960720 0.70 IGFBP3
insulin-like growth factor binding protein 3
206
0.94
chr8_19675079_19675230 0.70 INTS10
integrator complex subunit 10
503
0.86
chr6_33588468_33588675 0.69 ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
429
0.78
chr1_111888969_111889259 0.68 PIFO
primary cilia formation
128
0.94
chr13_74708852_74709026 0.68 KLF12
Kruppel-like factor 12
545
0.87
chr15_34658913_34659064 0.68 LPCAT4
lysophosphatidylcholine acyltransferase 4
491
0.68
chr2_145273344_145273561 0.67 ZEB2
zinc finger E-box binding homeobox 2
1663
0.39
chr13_75149843_75149994 0.65 LINC00381
long intergenic non-protein coding RNA 381
156608
0.04
chr2_241075882_241076184 0.63 MYEOV2
myeloma overexpressed 2
191
0.93
chr11_67981924_67982093 0.63 SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
713
0.7
chr1_167408539_167408792 0.63 RP11-104L21.2

19233
0.19
chr13_61988871_61989070 0.62 PCDH20
protocadherin 20
685
0.83
chr5_1111654_1111805 0.62 SLC12A7
solute carrier family 12 (potassium/chloride transporter), member 7
421
0.84
chr15_37393541_37393790 0.62 MEIS2
Meis homeobox 2
161
0.95
chr3_44063461_44063612 0.61 ENSG00000252980
.
49043
0.17
chr19_1455205_1455403 0.60 APC2
adenomatosis polyposis coli 2
3107
0.09
chr1_212458972_212459123 0.59 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
168
0.95
chr9_78506666_78506817 0.58 PCSK5
proprotein convertase subtilisin/kexin type 5
1120
0.6
chr14_90422513_90422664 0.58 TDP1
tyrosyl-DNA phosphodiesterase 1
207
0.93
chr20_3827146_3827376 0.58 MAVS
mitochondrial antiviral signaling protein
226
0.9
chr1_15479357_15479508 0.57 TMEM51
transmembrane protein 51
359
0.89
chr2_8822939_8823123 0.57 ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
845
0.49
chr8_133687798_133687949 0.56 LRRC6
leucine rich repeat containing 6
35
0.98
chr21_36398843_36398994 0.56 RUNX1
runt-related transcription factor 1
22544
0.28
chr22_19419614_19419913 0.56 MRPL40
mitochondrial ribosomal protein L40
338
0.57
chr18_22930641_22930889 0.56 ZNF521
zinc finger protein 521
392
0.91
chr1_100817300_100817579 0.56 CDC14A
cell division cycle 14A
149
0.96
chr19_10490874_10491025 0.55 TYK2
tyrosine kinase 2
237
0.86
chr5_127872829_127872980 0.55 FBN2
fibrillin 2
610
0.55
chr19_18314394_18314545 0.54 RAB3A
RAB3A, member RAS oncogene family
353
0.7
chr1_236305241_236305392 0.54 GPR137B
G protein-coupled receptor 137B
516
0.83
chr17_46675290_46675535 0.53 HOXB-AS3
HOXB cluster antisense RNA 3
1611
0.15
chr10_70586855_70587153 0.53 STOX1
storkhead box 1
294
0.88
chr12_22487742_22488002 0.53 ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
224
0.96
chr14_99712424_99712575 0.53 AL109767.1

16786
0.21
chr19_41111618_41111808 0.53 ENSG00000266164
.
1242
0.36
chr10_135191922_135192261 0.53 PAOX
polyamine oxidase (exo-N4-amino)
604
0.42
chrX_40014894_40015175 0.53 BCOR
BCL6 corepressor
9152
0.31
chr2_242743291_242743442 0.53 AC114730.5

2044
0.18
chr9_35814685_35814836 0.53 HINT2
histidine triad nucleotide binding protein 2
258
0.51
chr22_42196331_42196482 0.53 CCDC134
coiled-coil domain containing 134
277
0.86
chr1_151032362_151032626 0.52 CDC42SE1
CDC42 small effector 1
369
0.7
chr10_126850115_126850433 0.52 CTBP2
C-terminal binding protein 2
644
0.82
chr17_78010209_78010360 0.52 CCDC40
coiled-coil domain containing 40
151
0.86
chrX_45046544_45046746 0.52 RP11-342D14.1

4149
0.28
chr16_66914734_66914885 0.51 PDP2
pyruvate dehyrogenase phosphatase catalytic subunit 2
299
0.82
chr8_69243396_69243620 0.51 C8orf34
chromosome 8 open reading frame 34
48
0.73
chr11_17374505_17374976 0.51 NCR3LG1
natural killer cell cytotoxicity receptor 3 ligand 1
1467
0.37
chr12_102270610_102270783 0.51 DRAM1
DNA-damage regulated autophagy modulator 1
433
0.77
chr2_71356997_71357205 0.51 MCEE
methylmalonyl CoA epimerase
243
0.59
chr10_30681635_30681836 0.50 ENSG00000239625
.
26488
0.14
chr2_95825629_95825822 0.50 ZNF514
zinc finger protein 514
373
0.86
chr11_19734879_19735127 0.50 NAV2
neuron navigator 2
91
0.98
chr4_145567196_145567347 0.49 HHIP
hedgehog interacting protein
53
0.61
chr10_79470908_79471170 0.49 ENSG00000199664
.
65774
0.1
chr17_36903950_36904124 0.49 PCGF2
polycomb group ring finger 2
400
0.61
chr18_9474647_9474843 0.49 RALBP1
ralA binding protein 1
262
0.91
chr7_75268777_75268930 0.49 HIP1
huntingtin interacting protein 1
27692
0.17
chr19_3360665_3360877 0.49 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
1090
0.51
chr5_140855989_140856199 0.49 PCDHGC3
protocadherin gamma subfamily C, 3
514
0.58
chr4_110223862_110224013 0.49 COL25A1
collagen, type XXV, alpha 1
124
0.98
chr8_86090105_86090256 0.49 RP11-219B4.3

205
0.73
chr1_120254761_120254925 0.49 PHGDH
phosphoglycerate dehydrogenase
333
0.9
chr13_44361106_44361257 0.49 ENOX1
ecto-NOX disulfide-thiol exchanger 1
137
0.98
chr2_72370399_72370550 0.49 CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
261
0.96
chr5_122372371_122372688 0.48 PPIC
peptidylprolyl isomerase C (cyclophilin C)
93
0.88
chr4_72053181_72053414 0.48 SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
253
0.96
chr3_42623615_42623766 0.48 SEC22C
SEC22 vesicle trafficking protein homolog C (S. cerevisiae)
129
0.76
chr9_140063092_140063284 0.48 ENSG00000263697
.
534
0.44
chr17_46604448_46604599 0.48 HOXB1
homeobox B1
3749
0.11
chr17_80195806_80195957 0.48 SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
835
0.45
chr14_105953591_105953742 0.47 CRIP1
cysteine-rich protein 1 (intestinal)
412
0.72
chr12_124246600_124246751 0.47 DNAH10
dynein, axonemal, heavy chain 10
367
0.86
chr10_43724469_43724712 0.47 RASGEF1A
RasGEF domain family, member 1A
597
0.81
chr6_111136775_111136926 0.47 CDK19
cyclin-dependent kinase 19
10
0.98
chr2_232790866_232791017 0.46 NPPC
natriuretic peptide C
97
0.97
chr3_30706089_30706316 0.46 RP11-1024P17.1

32951
0.22
chr5_785429_785580 0.46 ZDHHC11B
zinc finger, DHHC-type containing 11B
18437
0.18
chr9_4985569_4985720 0.46 JAK2
Janus kinase 2
399
0.87
chr8_145911731_145911959 0.46 ARHGAP39
Rho GTPase activating protein 39
651
0.64
chr15_89921948_89922099 0.45 ENSG00000207819
.
10775
0.19
chr4_78740268_78740419 0.45 CNOT6L
CCR4-NOT transcription complex, subunit 6-like
126
0.98
chr19_49575697_49575848 0.45 KCNA7
potassium voltage-gated channel, shaker-related subfamily, member 7
426
0.58
chr2_71693925_71694106 0.45 DYSF
dysferlin
183
0.96
chr22_21738795_21738946 0.45 RIMBP3B
RIMS binding protein 3B
1207
0.32
chr3_184279586_184279889 0.45 EPHB3
EPH receptor B3
165
0.95
chr8_125739177_125739345 0.45 MTSS1
metastasis suppressor 1
596
0.82
chr5_149110542_149110693 0.45 PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
743
0.55
chr19_7566190_7566368 0.45 C19orf45
chromosome 19 open reading frame 45
1751
0.19
chr20_20693715_20693889 0.45 RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
671
0.78
chr9_137217343_137217691 0.44 RXRA
retinoid X receptor, alpha
909
0.68
chr13_100622875_100623026 0.44 ZIC5
Zic family member 5
1213
0.47
chr2_119604930_119605296 0.44 EN1
engrailed homeobox 1
141
0.98
chr12_96609154_96609428 0.44 RP11-394J1.2

8460
0.21
chr9_4741544_4741806 0.44 AK3
adenylate kinase 3
357
0.88
chr19_19650873_19651024 0.44 CILP2
cartilage intermediate layer protein 2
1874
0.22
chr14_24550508_24550659 0.44 NRL
neural retina leucine zipper
554
0.55
chr20_1306287_1306438 0.44 SDCBP2
syndecan binding protein (syntenin) 2
11
0.81
chr4_81187718_81187869 0.44 FGF5
fibroblast growth factor 5
0
0.98
chr1_51435046_51435197 0.44 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
495
0.82
chr16_88753084_88753235 0.44 SNAI3
snail family zinc finger 3
258
0.78
chr5_56205129_56205386 0.43 SETD9
SET domain containing 9
170
0.9
chr22_46367167_46367318 0.43 WNT7B
wingless-type MMTV integration site family, member 7B
1353
0.39
chr1_10755074_10755274 0.43 CASZ1
castor zinc finger 1
50041
0.13
chr9_140311679_140311830 0.43 ENSG00000272272
.
3842
0.13
chr16_11723487_11723878 0.43 LITAF
lipopolysaccharide-induced TNF factor
616
0.74
chr1_247274829_247274980 0.43 C1orf229
chromosome 1 open reading frame 229
815
0.57
chr13_24153555_24153706 0.43 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
111
0.98
chr5_111755059_111755337 0.43 EPB41L4A-AS2
EPB41L4A antisense RNA 2 (head to head)
82
0.65
chrX_129305590_129305741 0.42 RAB33A
RAB33A, member RAS oncogene family
42
0.98
chr17_79374508_79374888 0.42 ENSG00000266392
.
120
0.91
chr2_202507916_202508067 0.42 TMEM237
transmembrane protein 237
249
0.9
chr13_103451962_103452202 0.42 BIVM
basic, immunoglobulin-like variable motif containing
521
0.5
chr4_126237676_126237917 0.42 FAT4
FAT atypical cadherin 4
242
0.96
chr4_109089309_109089460 0.42 LEF1
lymphoid enhancer-binding factor 1
194
0.86
chr14_74079365_74079641 0.42 ACOT6
acyl-CoA thioesterase 6
1854
0.22
chr3_8543429_8543580 0.42 LMCD1
LIM and cysteine-rich domains 1
5
0.68
chr4_96470570_96470868 0.41 UNC5C
unc-5 homolog C (C. elegans)
362
0.56
chr9_137533869_137534020 0.41 COL5A1
collagen, type V, alpha 1
324
0.9
chr4_156681067_156681218 0.41 GUCY1B3
guanylate cyclase 1, soluble, beta 3
531
0.82
chr11_17035623_17035774 0.41 PLEKHA7
pleckstrin homology domain containing, family A member 7
261
0.88
chr9_87283140_87283301 0.41 NTRK2
neurotrophic tyrosine kinase, receptor, type 2
246
0.96
chr20_31071702_31071877 0.40 C20orf112
chromosome 20 open reading frame 112
404
0.85
chr22_20229992_20230143 0.40 RTN4R
reticulon 4 receptor
1140
0.39
chr15_101459055_101459206 0.40 RP11-66B24.4

84
0.77
chr16_66983063_66983214 0.40 CES2
carboxylesterase 2
8083
0.1
chr2_159825965_159826116 0.40 TANC1
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
857
0.65
chr17_41909606_41909769 0.40 MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
77
0.95
chr19_4279719_4279870 0.40 SHD
Src homology 2 domain containing transforming protein D
501
0.64
chr6_117586925_117587101 0.39 VGLL2
vestigial like 2 (Drosophila)
276
0.92
chr1_1141562_1141846 0.39 TNFRSF18
tumor necrosis factor receptor superfamily, member 18
247
0.81
chr1_208416915_208417066 0.39 PLXNA2
plexin A2
675
0.83
chr3_31573269_31573420 0.39 STT3B
STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
938
0.72
chr6_158937367_158937518 0.39 TMEM181
transmembrane protein 181
20026
0.21
chr2_68870926_68871154 0.39 PROKR1
prokineticin receptor 1
319
0.93
chr19_38810568_38810719 0.39 KCNK6
potassium channel, subfamily K, member 6
159
0.88
chr8_134308968_134309186 0.39 NDRG1
N-myc downstream regulated 1
258
0.95
chr11_44748743_44748894 0.39 TSPAN18
tetraspanin 18
94
0.98
chr2_183732037_183732193 0.39 FRZB
frizzled-related protein
225
0.94
chr11_85565582_85565753 0.39 AP000974.1
CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein
319
0.62
chr3_194407613_194407910 0.39 FAM43A
family with sequence similarity 43, member A
1139
0.42
chr22_19710642_19710976 0.39 GP1BB
glycoprotein Ib (platelet), beta polypeptide
341
0.86
chr16_727350_727692 0.38 RHBDL1
rhomboid, veinlet-like 1 (Drosophila)
1446
0.13
chr19_17346359_17346510 0.38 OCEL1
occludin/ELL domain containing 1
7369
0.08
chr17_4091398_4091549 0.38 ANKFY1
ankyrin repeat and FYVE domain containing 1
1069
0.36
chr2_1748595_1748841 0.38 PXDN
peroxidasin homolog (Drosophila)
440
0.89
chr15_72476609_72476869 0.38 GRAMD2
GRAM domain containing 2
13387
0.15
chr7_128530946_128531125 0.38 ENSG00000221401
.
15790
0.13
chr12_113507079_113507253 0.38 DTX1
deltex homolog 1 (Drosophila)
11671
0.16
chr12_51664020_51664171 0.38 SMAGP
small cell adhesion glycoprotein
27
0.97
chr2_42720318_42720469 0.38 KCNG3
potassium voltage-gated channel, subfamily G, member 3
724
0.58
chr5_102594916_102595067 0.38 C5orf30
chromosome 5 open reading frame 30
134
0.97
chr13_76055318_76055596 0.38 TBC1D4
TBC1 domain family, member 4
793
0.7
chr10_128076116_128076382 0.37 ADAM12
ADAM metallopeptidase domain 12
775
0.76
chr4_1769705_1769945 0.37 FGFR3
fibroblast growth factor receptor 3
25209
0.13
chr9_90341033_90341185 0.37 CTSL
cathepsin L
54
0.98
chr7_112090183_112090334 0.37 IFRD1
interferon-related developmental regulator 1
77
0.98
chr7_89841108_89841324 0.37 STEAP2
STEAP family member 2, metalloreductase
16
0.79
chr12_52702079_52702230 0.37 RP11-845M18.6

1
0.95
chr19_9968157_9968686 0.37 OLFM2
olfactomedin 2
423
0.71
chr3_26663426_26663700 0.37 LRRC3B
leucine rich repeat containing 3B
734
0.8
chr4_468151_468360 0.37 ZNF721
zinc finger protein 721
299
0.88
chr16_89883289_89883451 0.37 FANCA
Fanconi anemia, complementation group A
305
0.86
chr7_74508090_74508259 0.37 GTF2IRD2B
GTF2I repeat domain containing 2B
208
0.95
chr19_59025558_59025709 0.37 SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
2201
0.13
chr4_41748277_41748428 0.37 PHOX2B
paired-like homeobox 2b
1372
0.37
chr21_46438389_46438560 0.37 AP001579.1
Uncharacterized protein
54453
0.08
chr11_43963611_43963776 0.36 C11orf96
chromosome 11 open reading frame 96
362
0.85
chr17_60730352_60730503 0.36 ENSG00000207382
.
8659
0.17
chr7_148788116_148788334 0.36 ZNF786
zinc finger protein 786
351
0.84
chr7_8481771_8482008 0.36 NXPH1
neurexophilin 1
7064
0.32
chr2_232478652_232478803 0.36 C2orf57
chromosome 2 open reading frame 57
21152
0.15
chr7_74267960_74268143 0.36 GTF2IRD2
GTF2I repeat domain containing 2
204
0.94
chr3_46933845_46934001 0.36 AC109583.1
Uncharacterized protein
3752
0.17
chr7_91763215_91763366 0.36 CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
554
0.47
chr12_59314085_59314358 0.36 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
82
0.67
chr11_43965052_43965302 0.36 C11orf96
chromosome 11 open reading frame 96
1122
0.46
chr7_100807319_100807470 0.36 VGF
VGF nerve growth factor inducible
1001
0.35
chr20_31350708_31350965 0.36 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
388
0.86
chr12_133287769_133288024 0.36 PGAM5
phosphoglycerate mutase family member 5
228
0.89
chr1_35659017_35659485 0.35 SFPQ
splicing factor proline/glutamine-rich
502
0.75
chr17_75243284_75243621 0.35 SEPT9
septin 9
33199
0.16
chr6_20402900_20403051 0.35 E2F3
E2F transcription factor 3
577
0.71
chr9_133539441_133539614 0.35 PRDM12
PR domain containing 12
454
0.84
chr4_109089804_109089955 0.35 LEF1
lymphoid enhancer-binding factor 1
233
0.9
chr14_103987904_103988055 0.35 CKB
creatine kinase, brain
300
0.79
chr17_68165063_68165344 0.35 KCNJ2-AS1
KCNJ2 antisense RNA 1 (head to head)
340
0.53
chr9_98075609_98075760 0.35 FANCC
Fanconi anemia, complementation group C
3492
0.33
chr14_75745664_75745919 0.35 FOS
FBJ murine osteosarcoma viral oncogene homolog
111
0.96
chr13_100621996_100622147 0.35 ZIC5
Zic family member 5
2092
0.31
chr19_10397670_10397821 0.35 ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
65
0.91

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ZBTB14

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.2 0.7 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.2 0.5 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 0.4 GO:0003161 cardiac conduction system development(GO:0003161)
0.2 0.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 0.6 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.7 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 1.6 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.7 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.4 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.5 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.4 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.4 GO:0045112 integrin biosynthetic process(GO:0045112)
0.1 0.4 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.1 0.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.6 GO:1904376 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1 0.3 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.4 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.6 GO:0000012 single strand break repair(GO:0000012)
0.1 0.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.4 GO:0046881 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1 0.4 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 0.4 GO:0003417 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.1 0.3 GO:0071800 podosome assembly(GO:0071800)
0.1 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.3 GO:0009648 photoperiodism(GO:0009648)
0.1 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.2 GO:0060424 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.1 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 0.2 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1 0.2 GO:0060242 contact inhibition(GO:0060242)
0.1 0.3 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1 0.3 GO:0010823 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.1 0.2 GO:0071436 sodium ion export(GO:0071436)
0.1 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 0.2 GO:0042732 D-xylose metabolic process(GO:0042732)
0.1 0.3 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.1 GO:0032825 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1 0.1 GO:0001714 endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.1 0.8 GO:0016180 snRNA processing(GO:0016180)
0.1 0.6 GO:0050872 white fat cell differentiation(GO:0050872)
0.1 0.2 GO:0006565 L-serine catabolic process(GO:0006565)
0.1 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.3 GO:0010159 specification of organ position(GO:0010159)
0.1 0.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.3 GO:0001553 luteinization(GO:0001553)
0.1 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1 0.2 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.1 GO:0014044 Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0061043 vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.1 0.2 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.1 GO:0048541 Peyer's patch development(GO:0048541)
0.1 0.3 GO:0051642 centrosome localization(GO:0051642)
0.1 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.1 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.3 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.1 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.5 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.1 0.2 GO:0031297 replication fork processing(GO:0031297)
0.1 0.1 GO:0090286 nuclear matrix organization(GO:0043578) cytoskeletal anchoring at nuclear membrane(GO:0090286) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.2 GO:0022009 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.1 0.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.3 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.2 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.0 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.2 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.3 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.5 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.5 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0060911 cardiac cell fate commitment(GO:0060911)
0.0 0.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.4 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0071883 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.4 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.4 GO:0050812 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0090036 regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.1 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0050820 positive regulation of coagulation(GO:0050820)
0.0 0.1 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0046668 retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.3 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.1 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.6 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.5 GO:0090278 negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.1 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.0 0.3 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0040034 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 0.5 GO:0007140 male meiosis(GO:0007140)
0.0 0.2 GO:0031648 protein destabilization(GO:0031648)
0.0 0.5 GO:0051225 spindle assembly(GO:0051225)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0014002 astrocyte development(GO:0014002)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.2 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0051797 regulation of hair follicle development(GO:0051797)
0.0 0.6 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.2 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:0032306 regulation of icosanoid secretion(GO:0032303) positive regulation of icosanoid secretion(GO:0032305) regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) prostaglandin secretion(GO:0032310)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.5 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.4 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.0 GO:0090030 regulation of steroid hormone biosynthetic process(GO:0090030)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.0 GO:0033866 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.4 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.1 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.3 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.2 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.0 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0090102 cochlea development(GO:0090102)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0021612 cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.0 GO:0046958 nonassociative learning(GO:0046958)
0.0 0.0 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.1 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.2 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.0 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.0 GO:0042940 D-amino acid transport(GO:0042940) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.3 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0006388 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0071732 cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0 0.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.0 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.0 GO:0014010 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0 0.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:0003300 cardiac muscle hypertrophy(GO:0003300) striated muscle hypertrophy(GO:0014897)
0.0 0.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.0 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.1 GO:0015780 nucleotide-sugar transport(GO:0015780)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.0 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0010939 regulation of necrotic cell death(GO:0010939)
0.0 0.1 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.1 GO:1901216 positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0 0.0 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.8 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.0 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.1 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.2 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0032368 regulation of lipid transport(GO:0032368)
0.0 0.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0046184 aldehyde biosynthetic process(GO:0046184)
0.0 0.0 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:2001233 positive regulation of mitochondrion organization(GO:0010822) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200) regulation of apoptotic signaling pathway(GO:2001233) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0009414 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.0 GO:0021546 rhombomere development(GO:0021546)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.0 GO:0042069 regulation of catecholamine metabolic process(GO:0042069)
0.0 0.1 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0000966 RNA 5'-end processing(GO:0000966)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.0 GO:0051938 L-glutamate import(GO:0051938)
0.0 0.0 GO:0033261 obsolete regulation of S phase(GO:0033261)
0.0 0.0 GO:0070391 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0 0.2 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.2 GO:0006298 mismatch repair(GO:0006298)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0018208 peptidyl-proline modification(GO:0018208)
0.0 0.0 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.6 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.2 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.2 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.8 GO:0032039 integrator complex(GO:0032039)
0.1 0.3 GO:0001739 sex chromatin(GO:0001739)
0.1 0.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.5 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.1 0.4 GO:0001527 microfibril(GO:0001527)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.6 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.3 GO:0032421 stereocilium bundle(GO:0032421)
0.0 0.2 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 1.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.5 GO:0042383 sarcolemma(GO:0042383)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.0 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0030286 dynein complex(GO:0030286)
0.0 0.2 GO:0016460 myosin II complex(GO:0016460)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 1.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.1 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2 0.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.6 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2 0.8 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.5 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.5 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.5 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.3 GO:0016362 activin receptor activity, type II(GO:0016362)
0.1 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.4 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.3 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.5 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.3 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 1.4 GO:0045296 cadherin binding(GO:0045296)
0.1 0.6 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 0.2 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.4 GO:0051400 BH domain binding(GO:0051400)
0.1 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.2 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.2 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.5 GO:0030553 cGMP binding(GO:0030553)
0.0 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.3 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0050543 icosatetraenoic acid binding(GO:0050543)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0015368 calcium, potassium:sodium antiporter activity(GO:0008273) calcium:cation antiporter activity(GO:0015368)
0.0 0.5 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.0 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.3 GO:0051287 NAD binding(GO:0051287)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.3 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.2 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0070061 fructose binding(GO:0070061)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.5 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 1.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 2.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.5 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.1 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.0 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0032451 demethylase activity(GO:0032451)
0.0 0.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.0 GO:0005035 death receptor activity(GO:0005035)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.8 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.0 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.0 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.5 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.0 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.0 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.9 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0080032 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.0 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.0 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0019201 nucleotide kinase activity(GO:0019201)
0.0 0.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.0 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 0.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.0 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.7 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.3 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 0.7 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 2.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.7 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.7 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.0 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.0 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 1.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.0 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.8 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.0 REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES Genes involved in Transmembrane transport of small molecules
0.0 0.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation