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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for ZBTB14

Z-value: 2.29

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Transcription factors associated with ZBTB14

Gene Symbol	Gene ID	Gene Info
ZBTB14 Ensembl NCBI GeneCards UniProt	ENSG00000198081.6	zinc finger and BTB domain containing 14

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr18_5296007_5296158	ZBTB14	43	0.985748	0.95	8.9e-05	Click!
chr18_5295798_5295949	ZBTB14	166	0.971298	0.94	1.9e-04	Click!
chr18_5296626_5296854	ZBTB14	312	0.934832	0.82	6.9e-03	Click!
chr18_5294570_5294721	ZBTB14	178	0.969051	0.45	2.2e-01	Click!
chr18_5288553_5288704	ZBTB14	6195	0.292336	-0.37	3.2e-01	Click!

Activity of the ZBTB14 motif across conditions

Conditions sorted by the z-value of the ZBTB14 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_73344221_73344400	1.41	NEO1	neogenin 1	259	0.96
chr8_21966484_21966635	0.97	NUDT18	nudix (nucleoside diphosphate linked moiety X)-type motif 18	351	0.79
chr7_155088808_155089052	0.89	INSIG1	insulin induced gene 1	556	0.8
chr11_66384282_66384433	0.79	RBM14	RNA binding motif protein 14	171	0.41
chr14_23426380_23426575	0.77	HAUS4	HAUS augmin-like complex, subunit 4	107	0.66
chr19_49339202_49339632	0.74	HSD17B14	hydroxysteroid (17-beta) dehydrogenase 14	337	0.76
chr4_24474546_24474697	0.73	ENSG00000265001	.	43166	0.14
chr22_41681891_41682042	0.72	RANGAP1	Ran GTPase activating protein 1	3	0.96
chr5_180616538_180616689	0.71	CTC-338M12.5		2311	0.14
chr7_45960569_45960720	0.70	IGFBP3	insulin-like growth factor binding protein 3	206	0.94
chr8_19675079_19675230	0.70	INTS10	integrator complex subunit 10	503	0.86
chr6_33588468_33588675	0.69	ITPR3	inositol 1,4,5-trisphosphate receptor, type 3	429	0.78
chr1_111888969_111889259	0.68	PIFO	primary cilia formation	128	0.94
chr13_74708852_74709026	0.68	KLF12	Kruppel-like factor 12	545	0.87
chr15_34658913_34659064	0.68	LPCAT4	lysophosphatidylcholine acyltransferase 4	491	0.68
chr2_145273344_145273561	0.67	ZEB2	zinc finger E-box binding homeobox 2	1663	0.39
chr13_75149843_75149994	0.65	LINC00381	long intergenic non-protein coding RNA 381	156608	0.04
chr2_241075882_241076184	0.63	MYEOV2	myeloma overexpressed 2	191	0.93
chr11_67981924_67982093	0.63	SUV420H1	suppressor of variegation 4-20 homolog 1 (Drosophila)	713	0.7
chr1_167408539_167408792	0.63	RP11-104L21.2		19233	0.19
chr13_61988871_61989070	0.62	PCDH20	protocadherin 20	685	0.83
chr5_1111654_1111805	0.62	SLC12A7	solute carrier family 12 (potassium/chloride transporter), member 7	421	0.84
chr15_37393541_37393790	0.62	MEIS2	Meis homeobox 2	161	0.95
chr3_44063461_44063612	0.61	ENSG00000252980	.	49043	0.17
chr19_1455205_1455403	0.60	APC2	adenomatosis polyposis coli 2	3107	0.09
chr1_212458972_212459123	0.59	PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	168	0.95
chr9_78506666_78506817	0.58	PCSK5	proprotein convertase subtilisin/kexin type 5	1120	0.6
chr14_90422513_90422664	0.58	TDP1	tyrosyl-DNA phosphodiesterase 1	207	0.93
chr20_3827146_3827376	0.58	MAVS	mitochondrial antiviral signaling protein	226	0.9
chr1_15479357_15479508	0.57	TMEM51	transmembrane protein 51	359	0.89
chr2_8822939_8823123	0.57	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	845	0.49
chr8_133687798_133687949	0.56	LRRC6	leucine rich repeat containing 6	35	0.98
chr21_36398843_36398994	0.56	RUNX1	runt-related transcription factor 1	22544	0.28
chr22_19419614_19419913	0.56	MRPL40	mitochondrial ribosomal protein L40	338	0.57
chr18_22930641_22930889	0.56	ZNF521	zinc finger protein 521	392	0.91
chr1_100817300_100817579	0.56	CDC14A	cell division cycle 14A	149	0.96
chr19_10490874_10491025	0.55	TYK2	tyrosine kinase 2	237	0.86
chr5_127872829_127872980	0.55	FBN2	fibrillin 2	610	0.55
chr19_18314394_18314545	0.54	RAB3A	RAB3A, member RAS oncogene family	353	0.7
chr1_236305241_236305392	0.54	GPR137B	G protein-coupled receptor 137B	516	0.83
chr17_46675290_46675535	0.53	HOXB-AS3	HOXB cluster antisense RNA 3	1611	0.15
chr10_70586855_70587153	0.53	STOX1	storkhead box 1	294	0.88
chr12_22487742_22488002	0.53	ST8SIA1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	224	0.96
chr14_99712424_99712575	0.53	AL109767.1		16786	0.21
chr19_41111618_41111808	0.53	ENSG00000266164	.	1242	0.36
chr10_135191922_135192261	0.53	PAOX	polyamine oxidase (exo-N4-amino)	604	0.42
chrX_40014894_40015175	0.53	BCOR	BCL6 corepressor	9152	0.31
chr2_242743291_242743442	0.53	AC114730.5		2044	0.18
chr9_35814685_35814836	0.53	HINT2	histidine triad nucleotide binding protein 2	258	0.51
chr22_42196331_42196482	0.53	CCDC134	coiled-coil domain containing 134	277	0.86
chr1_151032362_151032626	0.52	CDC42SE1	CDC42 small effector 1	369	0.7
chr10_126850115_126850433	0.52	CTBP2	C-terminal binding protein 2	644	0.82
chr17_78010209_78010360	0.52	CCDC40	coiled-coil domain containing 40	151	0.86
chrX_45046544_45046746	0.52	RP11-342D14.1		4149	0.28
chr16_66914734_66914885	0.51	PDP2	pyruvate dehyrogenase phosphatase catalytic subunit 2	299	0.82
chr8_69243396_69243620	0.51	C8orf34	chromosome 8 open reading frame 34	48	0.73
chr11_17374505_17374976	0.51	NCR3LG1	natural killer cell cytotoxicity receptor 3 ligand 1	1467	0.37
chr12_102270610_102270783	0.51	DRAM1	DNA-damage regulated autophagy modulator 1	433	0.77
chr2_71356997_71357205	0.51	MCEE	methylmalonyl CoA epimerase	243	0.59
chr10_30681635_30681836	0.50	ENSG00000239625	.	26488	0.14
chr2_95825629_95825822	0.50	ZNF514	zinc finger protein 514	373	0.86
chr11_19734879_19735127	0.50	NAV2	neuron navigator 2	91	0.98
chr4_145567196_145567347	0.49	HHIP	hedgehog interacting protein	53	0.61
chr10_79470908_79471170	0.49	ENSG00000199664	.	65774	0.1
chr17_36903950_36904124	0.49	PCGF2	polycomb group ring finger 2	400	0.61
chr18_9474647_9474843	0.49	RALBP1	ralA binding protein 1	262	0.91
chr7_75268777_75268930	0.49	HIP1	huntingtin interacting protein 1	27692	0.17
chr19_3360665_3360877	0.49	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	1090	0.51
chr5_140855989_140856199	0.49	PCDHGC3	protocadherin gamma subfamily C, 3	514	0.58
chr4_110223862_110224013	0.49	COL25A1	collagen, type XXV, alpha 1	124	0.98
chr8_86090105_86090256	0.49	RP11-219B4.3		205	0.73
chr1_120254761_120254925	0.49	PHGDH	phosphoglycerate dehydrogenase	333	0.9
chr13_44361106_44361257	0.49	ENOX1	ecto-NOX disulfide-thiol exchanger 1	137	0.98
chr2_72370399_72370550	0.49	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1	261	0.96
chr5_122372371_122372688	0.48	PPIC	peptidylprolyl isomerase C (cyclophilin C)	93	0.88
chr4_72053181_72053414	0.48	SLC4A4	solute carrier family 4 (sodium bicarbonate cotransporter), member 4	253	0.96
chr3_42623615_42623766	0.48	SEC22C	SEC22 vesicle trafficking protein homolog C (S. cerevisiae)	129	0.76
chr9_140063092_140063284	0.48	ENSG00000263697	.	534	0.44
chr17_46604448_46604599	0.48	HOXB1	homeobox B1	3749	0.11
chr17_80195806_80195957	0.48	SLC16A3	solute carrier family 16 (monocarboxylate transporter), member 3	835	0.45
chr14_105953591_105953742	0.47	CRIP1	cysteine-rich protein 1 (intestinal)	412	0.72
chr12_124246600_124246751	0.47	DNAH10	dynein, axonemal, heavy chain 10	367	0.86
chr10_43724469_43724712	0.47	RASGEF1A	RasGEF domain family, member 1A	597	0.81
chr6_111136775_111136926	0.47	CDK19	cyclin-dependent kinase 19	10	0.98
chr2_232790866_232791017	0.46	NPPC	natriuretic peptide C	97	0.97
chr3_30706089_30706316	0.46	RP11-1024P17.1		32951	0.22
chr5_785429_785580	0.46	ZDHHC11B	zinc finger, DHHC-type containing 11B	18437	0.18
chr9_4985569_4985720	0.46	JAK2	Janus kinase 2	399	0.87
chr8_145911731_145911959	0.46	ARHGAP39	Rho GTPase activating protein 39	651	0.64
chr15_89921948_89922099	0.45	ENSG00000207819	.	10775	0.19
chr4_78740268_78740419	0.45	CNOT6L	CCR4-NOT transcription complex, subunit 6-like	126	0.98
chr19_49575697_49575848	0.45	KCNA7	potassium voltage-gated channel, shaker-related subfamily, member 7	426	0.58
chr2_71693925_71694106	0.45	DYSF	dysferlin	183	0.96
chr22_21738795_21738946	0.45	RIMBP3B	RIMS binding protein 3B	1207	0.32
chr3_184279586_184279889	0.45	EPHB3	EPH receptor B3	165	0.95
chr8_125739177_125739345	0.45	MTSS1	metastasis suppressor 1	596	0.82
chr5_149110542_149110693	0.45	PPARGC1B	peroxisome proliferator-activated receptor gamma, coactivator 1 beta	743	0.55
chr19_7566190_7566368	0.45	C19orf45	chromosome 19 open reading frame 45	1751	0.19
chr20_20693715_20693889	0.45	RALGAPA2	Ral GTPase activating protein, alpha subunit 2 (catalytic)	671	0.78
chr9_137217343_137217691	0.44	RXRA	retinoid X receptor, alpha	909	0.68
chr13_100622875_100623026	0.44	ZIC5	Zic family member 5	1213	0.47
chr2_119604930_119605296	0.44	EN1	engrailed homeobox 1	141	0.98
chr12_96609154_96609428	0.44	RP11-394J1.2		8460	0.21
chr9_4741544_4741806	0.44	AK3	adenylate kinase 3	357	0.88
chr19_19650873_19651024	0.44	CILP2	cartilage intermediate layer protein 2	1874	0.22
chr14_24550508_24550659	0.44	NRL	neural retina leucine zipper	554	0.55
chr20_1306287_1306438	0.44	SDCBP2	syndecan binding protein (syntenin) 2	11	0.81
chr4_81187718_81187869	0.44	FGF5	fibroblast growth factor 5	0	0.98
chr1_51435046_51435197	0.44	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	495	0.82
chr16_88753084_88753235	0.44	SNAI3	snail family zinc finger 3	258	0.78
chr5_56205129_56205386	0.43	SETD9	SET domain containing 9	170	0.9
chr22_46367167_46367318	0.43	WNT7B	wingless-type MMTV integration site family, member 7B	1353	0.39
chr1_10755074_10755274	0.43	CASZ1	castor zinc finger 1	50041	0.13
chr9_140311679_140311830	0.43	ENSG00000272272	.	3842	0.13
chr16_11723487_11723878	0.43	LITAF	lipopolysaccharide-induced TNF factor	616	0.74
chr1_247274829_247274980	0.43	C1orf229	chromosome 1 open reading frame 229	815	0.57
chr13_24153555_24153706	0.43	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	111	0.98
chr5_111755059_111755337	0.43	EPB41L4A-AS2	EPB41L4A antisense RNA 2 (head to head)	82	0.65
chrX_129305590_129305741	0.42	RAB33A	RAB33A, member RAS oncogene family	42	0.98
chr17_79374508_79374888	0.42	ENSG00000266392	.	120	0.91
chr2_202507916_202508067	0.42	TMEM237	transmembrane protein 237	249	0.9
chr13_103451962_103452202	0.42	BIVM	basic, immunoglobulin-like variable motif containing	521	0.5
chr4_126237676_126237917	0.42	FAT4	FAT atypical cadherin 4	242	0.96
chr4_109089309_109089460	0.42	LEF1	lymphoid enhancer-binding factor 1	194	0.86
chr14_74079365_74079641	0.42	ACOT6	acyl-CoA thioesterase 6	1854	0.22
chr3_8543429_8543580	0.42	LMCD1	LIM and cysteine-rich domains 1	5	0.68
chr4_96470570_96470868	0.41	UNC5C	unc-5 homolog C (C. elegans)	362	0.56
chr9_137533869_137534020	0.41	COL5A1	collagen, type V, alpha 1	324	0.9
chr4_156681067_156681218	0.41	GUCY1B3	guanylate cyclase 1, soluble, beta 3	531	0.82
chr11_17035623_17035774	0.41	PLEKHA7	pleckstrin homology domain containing, family A member 7	261	0.88
chr9_87283140_87283301	0.41	NTRK2	neurotrophic tyrosine kinase, receptor, type 2	246	0.96
chr20_31071702_31071877	0.40	C20orf112	chromosome 20 open reading frame 112	404	0.85
chr22_20229992_20230143	0.40	RTN4R	reticulon 4 receptor	1140	0.39
chr15_101459055_101459206	0.40	RP11-66B24.4		84	0.77
chr16_66983063_66983214	0.40	CES2	carboxylesterase 2	8083	0.1
chr2_159825965_159826116	0.40	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	857	0.65
chr17_41909606_41909769	0.40	MPP3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	77	0.95
chr19_4279719_4279870	0.40	SHD	Src homology 2 domain containing transforming protein D	501	0.64
chr6_117586925_117587101	0.39	VGLL2	vestigial like 2 (Drosophila)	276	0.92
chr1_1141562_1141846	0.39	TNFRSF18	tumor necrosis factor receptor superfamily, member 18	247	0.81
chr1_208416915_208417066	0.39	PLXNA2	plexin A2	675	0.83
chr3_31573269_31573420	0.39	STT3B	STT3B, subunit of the oligosaccharyltransferase complex (catalytic)	938	0.72
chr6_158937367_158937518	0.39	TMEM181	transmembrane protein 181	20026	0.21
chr2_68870926_68871154	0.39	PROKR1	prokineticin receptor 1	319	0.93
chr19_38810568_38810719	0.39	KCNK6	potassium channel, subfamily K, member 6	159	0.88
chr8_134308968_134309186	0.39	NDRG1	N-myc downstream regulated 1	258	0.95
chr11_44748743_44748894	0.39	TSPAN18	tetraspanin 18	94	0.98
chr2_183732037_183732193	0.39	FRZB	frizzled-related protein	225	0.94
chr11_85565582_85565753	0.39	AP000974.1	CDNA FLJ26432 fis, clone KDN01418; Uncharacterized protein	319	0.62
chr3_194407613_194407910	0.39	FAM43A	family with sequence similarity 43, member A	1139	0.42
chr22_19710642_19710976	0.39	GP1BB	glycoprotein Ib (platelet), beta polypeptide	341	0.86
chr16_727350_727692	0.38	RHBDL1	rhomboid, veinlet-like 1 (Drosophila)	1446	0.13
chr19_17346359_17346510	0.38	OCEL1	occludin/ELL domain containing 1	7369	0.08
chr17_4091398_4091549	0.38	ANKFY1	ankyrin repeat and FYVE domain containing 1	1069	0.36
chr2_1748595_1748841	0.38	PXDN	peroxidasin homolog (Drosophila)	440	0.89
chr15_72476609_72476869	0.38	GRAMD2	GRAM domain containing 2	13387	0.15
chr7_128530946_128531125	0.38	ENSG00000221401	.	15790	0.13
chr12_113507079_113507253	0.38	DTX1	deltex homolog 1 (Drosophila)	11671	0.16
chr12_51664020_51664171	0.38	SMAGP	small cell adhesion glycoprotein	27	0.97
chr2_42720318_42720469	0.38	KCNG3	potassium voltage-gated channel, subfamily G, member 3	724	0.58
chr5_102594916_102595067	0.38	C5orf30	chromosome 5 open reading frame 30	134	0.97
chr13_76055318_76055596	0.38	TBC1D4	TBC1 domain family, member 4	793	0.7
chr10_128076116_128076382	0.37	ADAM12	ADAM metallopeptidase domain 12	775	0.76
chr4_1769705_1769945	0.37	FGFR3	fibroblast growth factor receptor 3	25209	0.13
chr9_90341033_90341185	0.37	CTSL	cathepsin L	54	0.98
chr7_112090183_112090334	0.37	IFRD1	interferon-related developmental regulator 1	77	0.98
chr7_89841108_89841324	0.37	STEAP2	STEAP family member 2, metalloreductase	16	0.79
chr12_52702079_52702230	0.37	RP11-845M18.6		1	0.95
chr19_9968157_9968686	0.37	OLFM2	olfactomedin 2	423	0.71
chr3_26663426_26663700	0.37	LRRC3B	leucine rich repeat containing 3B	734	0.8
chr4_468151_468360	0.37	ZNF721	zinc finger protein 721	299	0.88
chr16_89883289_89883451	0.37	FANCA	Fanconi anemia, complementation group A	305	0.86
chr7_74508090_74508259	0.37	GTF2IRD2B	GTF2I repeat domain containing 2B	208	0.95
chr19_59025558_59025709	0.37	SLC27A5	solute carrier family 27 (fatty acid transporter), member 5	2201	0.13
chr4_41748277_41748428	0.37	PHOX2B	paired-like homeobox 2b	1372	0.37
chr21_46438389_46438560	0.37	AP001579.1	Uncharacterized protein	54453	0.08
chr11_43963611_43963776	0.36	C11orf96	chromosome 11 open reading frame 96	362	0.85
chr17_60730352_60730503	0.36	ENSG00000207382	.	8659	0.17
chr7_148788116_148788334	0.36	ZNF786	zinc finger protein 786	351	0.84
chr7_8481771_8482008	0.36	NXPH1	neurexophilin 1	7064	0.32
chr2_232478652_232478803	0.36	C2orf57	chromosome 2 open reading frame 57	21152	0.15
chr7_74267960_74268143	0.36	GTF2IRD2	GTF2I repeat domain containing 2	204	0.94
chr3_46933845_46934001	0.36	AC109583.1	Uncharacterized protein	3752	0.17
chr7_91763215_91763366	0.36	CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1	554	0.47
chr12_59314085_59314358	0.36	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	82	0.67
chr11_43965052_43965302	0.36	C11orf96	chromosome 11 open reading frame 96	1122	0.46
chr7_100807319_100807470	0.36	VGF	VGF nerve growth factor inducible	1001	0.35
chr20_31350708_31350965	0.36	DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	388	0.86
chr12_133287769_133288024	0.36	PGAM5	phosphoglycerate mutase family member 5	228	0.89
chr1_35659017_35659485	0.35	SFPQ	splicing factor proline/glutamine-rich	502	0.75
chr17_75243284_75243621	0.35	SEPT9	septin 9	33199	0.16
chr6_20402900_20403051	0.35	E2F3	E2F transcription factor 3	577	0.71
chr9_133539441_133539614	0.35	PRDM12	PR domain containing 12	454	0.84
chr4_109089804_109089955	0.35	LEF1	lymphoid enhancer-binding factor 1	233	0.9
chr14_103987904_103988055	0.35	CKB	creatine kinase, brain	300	0.79
chr17_68165063_68165344	0.35	KCNJ2-AS1	KCNJ2 antisense RNA 1 (head to head)	340	0.53
chr9_98075609_98075760	0.35	FANCC	Fanconi anemia, complementation group C	3492	0.33
chr14_75745664_75745919	0.35	FOS	FBJ murine osteosarcoma viral oncogene homolog	111	0.96
chr13_100621996_100622147	0.35	ZIC5	Zic family member 5	2092	0.31
chr19_10397670_10397821	0.35	ICAM4	intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)	65	0.91

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB14

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.2	0.7	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.2	0.5	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.4	GO:0003161	cardiac conduction system development(GO:0003161)
0.2	0.5	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2	0.6	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.1	0.7	GO:0071501	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	1.6	GO:0007520	myoblast fusion(GO:0007520)
0.1	0.7	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.1	0.4	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.1	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	0.5	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.5	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	0.4	GO:0034653	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.4	GO:0045112	integrin biosynthetic process(GO:0045112)
0.1	0.4	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.1	0.4	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.6	GO:1904376	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.1	0.3	GO:0001661	conditioned taste aversion(GO:0001661)
0.1	0.2	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.4	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.2	GO:0000212	meiotic spindle organization(GO:0000212)
0.1	0.3	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.6	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.1	0.6	GO:0000012	single strand break repair(GO:0000012)
0.1	0.8	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.1	0.4	GO:0046881	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1	0.4	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.3	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.1	0.4	GO:0003417	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.1	0.3	GO:0071800	podosome assembly(GO:0071800)
0.1	0.2	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.3	GO:0009648	photoperiodism(GO:0009648)
0.1	0.3	GO:0046548	retinal rod cell development(GO:0046548)
0.1	0.2	GO:0060424	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1	0.1	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.2	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.1	0.2	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.2	GO:0060242	contact inhibition(GO:0060242)
0.1	0.3	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.1	0.3	GO:0010823	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.1	0.2	GO:0071436	sodium ion export(GO:0071436)
0.1	0.2	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.3	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.1	0.2	GO:0042732	D-xylose metabolic process(GO:0042732)
0.1	0.3	GO:0034214	protein hexamerization(GO:0034214)
0.1	0.1	GO:0032825	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1	0.1	GO:0001714	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	0.8	GO:0016180	snRNA processing(GO:0016180)
0.1	0.6	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.2	GO:0006565	L-serine catabolic process(GO:0006565)
0.1	0.5	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	0.3	GO:0010159	specification of organ position(GO:0010159)
0.1	0.3	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.3	GO:0001553	luteinization(GO:0001553)
0.1	0.2	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.1	0.4	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.1	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.2	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.1	GO:0014044	Schwann cell development(GO:0014044) myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.2	GO:0061043	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.1	0.2	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.1	GO:0048541	Peyer's patch development(GO:0048541)
0.1	0.3	GO:0051642	centrosome localization(GO:0051642)
0.1	0.3	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.1	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.1	0.3	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.1	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	0.5	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.1	0.2	GO:0031297	replication fork processing(GO:0031297)
0.1	0.1	GO:0090286	nuclear matrix organization(GO:0043578) cytoskeletal anchoring at nuclear membrane(GO:0090286) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.2	GO:0022009	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.1	0.3	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.1	0.3	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.1	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.4	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.0	0.2	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.2	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.3	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.5	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.0	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.5	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.2	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.6	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.2	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.1	GO:0060911	cardiac cell fate commitment(GO:0060911)
0.0	0.1	GO:0010996	response to auditory stimulus(GO:0010996)
0.0	0.1	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.7	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.2	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.4	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0071883	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.4	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.4	GO:0050812	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.5	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0090036	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.1	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.7	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.2	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.3	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0050820	positive regulation of coagulation(GO:0050820)
0.0	0.1	GO:0022030	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0046668	retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.3	GO:0051602	response to electrical stimulus(GO:0051602)
0.0	0.1	GO:0045006	DNA deamination(GO:0045006)
0.0	0.1	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.1	GO:0048266	behavioral response to pain(GO:0048266)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.6	GO:0006706	steroid catabolic process(GO:0006706)
0.0	0.1	GO:0072070	loop of Henle development(GO:0072070)
0.0	0.5	GO:0090278	negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.1	GO:0042762	regulation of sulfur metabolic process(GO:0042762)
0.0	0.3	GO:0098876	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0040034	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.4	GO:0090630	activation of GTPase activity(GO:0090630)
0.0	0.2	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.2	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.5	GO:0007140	male meiosis(GO:0007140)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.5	GO:0051225	spindle assembly(GO:0051225)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0014002	astrocyte development(GO:0014002)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.2	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.2	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0051797	regulation of hair follicle development(GO:0051797)
0.0	0.6	GO:0034968	histone lysine methylation(GO:0034968)
0.0	0.2	GO:2000273	positive regulation of receptor activity(GO:2000273)
0.0	0.1	GO:0032306	regulation of icosanoid secretion(GO:0032303) positive regulation of icosanoid secretion(GO:0032305) regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) prostaglandin secretion(GO:0032310)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.5	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.4	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.0	GO:0090030	regulation of steroid hormone biosynthetic process(GO:0090030)
0.0	0.2	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.0	GO:0033866	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.4	GO:0090303	positive regulation of wound healing(GO:0090303)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.3	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.2	GO:0032924	activin receptor signaling pathway(GO:0032924)
0.0	0.3	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.1	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.2	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0090102	cochlea development(GO:0090102)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.0	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.0	GO:0021612	cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612)
0.0	0.1	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.0	GO:0046958	nonassociative learning(GO:0046958)
0.0	0.0	GO:0048016	inositol phosphate-mediated signaling(GO:0048016)
0.0	0.1	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.2	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.0	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.3	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.0	GO:0042940	D-amino acid transport(GO:0042940) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.3	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.4	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.0	GO:0071732	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0	0.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.1	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.0	GO:0014010	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.1	GO:0003300	cardiac muscle hypertrophy(GO:0003300) striated muscle hypertrophy(GO:0014897)
0.0	0.1	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.0	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.0	0.0	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.0	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.0	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.0	GO:0010939	regulation of necrotic cell death(GO:0010939)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.1	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.2	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.0	0.1	GO:1901216	positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0	0.0	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.8	GO:0015718	monocarboxylic acid transport(GO:0015718)
0.0	0.0	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.1	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.0	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.0	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.2	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.2	GO:0032368	regulation of lipid transport(GO:0032368)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.0	0.0	GO:0031659	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:2001233	positive regulation of mitochondrion organization(GO:0010822) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200) regulation of apoptotic signaling pathway(GO:2001233) positive regulation of apoptotic signaling pathway(GO:2001235)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.0	GO:0021546	rhombomere development(GO:0021546)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.0	GO:0042069	regulation of catecholamine metabolic process(GO:0042069)
0.0	0.1	GO:0045823	positive regulation of heart contraction(GO:0045823)
0.0	0.1	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.0	GO:0072033	renal vesicle formation(GO:0072033)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:0044253	positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0	0.0	GO:0051938	L-glutamate import(GO:0051938)
0.0	0.0	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.0	GO:0070391	response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0	0.2	GO:0006691	leukotriene metabolic process(GO:0006691)
0.0	0.2	GO:0006298	mismatch repair(GO:0006298)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.2	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.0	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.1	GO:0043260	laminin-11 complex(GO:0043260)
0.1	0.4	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.3	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.3	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.6	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.2	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1	0.2	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	0.2	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	0.8	GO:0032039	integrator complex(GO:0032039)
0.1	0.3	GO:0001739	sex chromatin(GO:0001739)
0.1	0.2	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	0.5	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.1	0.4	GO:0001527	microfibril(GO:0001527)
0.1	0.5	GO:0070652	HAUS complex(GO:0070652)
0.1	0.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.3	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.3	GO:0042382	paraspeckles(GO:0042382)
0.0	0.4	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.3	GO:0005915	zonula adherens(GO:0005915)
0.0	0.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.2	GO:0032059	bleb(GO:0032059)
0.0	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.4	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.8	GO:0016592	mediator complex(GO:0016592)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.2	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.6	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.3	GO:0042588	zymogen granule(GO:0042588)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.3	GO:0030914	STAGA complex(GO:0030914)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.3	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.4	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.3	GO:0032421	stereocilium bundle(GO:0032421)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.4	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.2	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	2.0	GO:0031965	nuclear membrane(GO:0031965)
0.0	1.5	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.4	GO:0031526	brush border membrane(GO:0031526)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.5	GO:0042383	sarcolemma(GO:0042383)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0005771	multivesicular body(GO:0005771)
0.0	0.0	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.0	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.0	GO:0030056	hemidesmosome(GO:0030056)
0.0	1.0	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.3	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.4	GO:0030286	dynein complex(GO:0030286)
0.0	0.2	GO:0016460	myosin II complex(GO:0016460)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0032982	myosin filament(GO:0032982)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	1.0	GO:0098852	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	0.1	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2	0.8	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.2	0.6	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.2	0.8	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.6	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.4	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	0.4	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	0.5	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.5	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.5	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	0.5	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.3	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.3	GO:0016362	activin receptor activity, type II(GO:0016362)
0.1	0.3	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.3	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.3	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	0.3	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.4	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.5	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.3	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.4	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	1.4	GO:0045296	cadherin binding(GO:0045296)
0.1	0.6	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.1	0.2	GO:0005042	netrin receptor activity(GO:0005042)
0.1	0.5	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	0.4	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.5	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.3	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.2	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1	0.3	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	0.5	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.1	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.2	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	0.7	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.4	GO:0051400	BH domain binding(GO:0051400)
0.1	0.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	0.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.5	GO:0001671	ATPase activator activity(GO:0001671)
0.1	0.5	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.3	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1	0.7	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.2	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	0.2	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.3	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.2	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.3	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.2	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.4	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.7	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.3	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.5	GO:0030553	cGMP binding(GO:0030553)
0.0	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.2	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.3	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.2	GO:0050543	icosatetraenoic acid binding(GO:0050543)
0.0	0.3	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.7	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.4	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	1.0	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.0	0.3	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.2	GO:0015368	calcium, potassium:sodium antiporter activity(GO:0008273) calcium:cation antiporter activity(GO:0015368)
0.0	0.5	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	0.2	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	1.3	GO:0051287	NAD binding(GO:0051287)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.2	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.3	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.2	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.5	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0070061	fructose binding(GO:0070061)
0.0	0.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.5	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	1.2	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.3	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.3	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.3	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	0.1	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.0	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.3	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.6	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.5	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	2.4	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.5	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.2	GO:0004675	transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0004936	alpha-adrenergic receptor activity(GO:0004936)
0.0	0.1	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.5	GO:0019208	phosphatase regulator activity(GO:0019208)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.6	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.3	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.3	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.1	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	0.0	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.0	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.0	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.2	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0032451	demethylase activity(GO:0032451)
0.0	0.1	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.0	GO:0005035	death receptor activity(GO:0005035)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.8	GO:0004527	exonuclease activity(GO:0004527)
0.0	0.0	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.5	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.0	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.0	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.2	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.2	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.9	GO:0050839	cell adhesion molecule binding(GO:0050839)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.0	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0080032	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.2	GO:0003727	single-stranded RNA binding(GO:0003727)
0.0	0.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.0	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.0	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0019201	nucleotide kinase activity(GO:0019201)
0.0	0.1	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.5	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.0	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.3	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.3	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.1	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	0.3	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.1	0.7	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	2.3	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.9	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.7	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID FOXO PATHWAY	FoxO family signaling
0.0	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	1.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.7	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.7	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	1.6	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.7	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.4	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.5	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.6	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.4	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.6	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.9	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.3	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.5	PID BMP PATHWAY	BMP receptor signaling
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.5	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.1	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.4	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.6	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.1	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.3	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.3	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	0.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.3	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.1	0.7	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.1	2.0	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.6	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.7	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	1.1	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.3	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.7	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.5	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.7	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.5	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.7	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.6	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.5	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.3	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.0	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.3	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	1.5	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.0	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.5	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.4	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	1.1	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.3	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.8	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.5	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.0	0.1	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.0	REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES	Genes involved in Transmembrane transport of small molecules
0.0	0.3	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation

Results for ZBTB14

Z-value: 2.29

Motif logo

Transcription factors associated with ZBTB14

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ZBTB14 motif across conditions

Conditions sorted by the z-value of the ZBTB14 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB14

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: