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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ZBTB18

Z-value: 2.07

Motif logo

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Transcription factors associated with ZBTB18

Gene Symbol Gene ID Gene Info
ZBTB18
ENSG00000179456.9 zinc finger and BTB domain containing 18

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_244217966_244218117ZBTB1834560.265015-0.809.7e-03Click!
chr1_244210618_244210958ZBTB1837970.264146-0.761.7e-02Click!
chr1_244165402_244165576ZBTB18490960.149266-0.684.4e-02Click!
chr1_244214937_244215088ZBTB184270.859900-0.618.1e-02Click!
chr1_244215609_244215953ZBTB1811960.521680-0.608.9e-02Click!

Activity of the ZBTB18 motif across conditions

Conditions sorted by the z-value of the ZBTB18 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_40100780_40100931 0.90 RP1-144F13.3
1767
 0.23
chr2_238131211_238131483 0.87 AC112715.2
 Uncharacterized protein
 34387
 0.2
chr17_48343728_48343879 0.71 TMEM92
 transmembrane protein 92
 4964
 0.14
chr17_71039617_71039918 0.70 SLC39A11
 solute carrier family 39, member 11
 46136
 0.17
chr12_28721330_28721481 0.67 CCDC91
 coiled-coil domain containing 91
 19408
 0.26
chr5_56833824_56833975 0.66 ACTBL2
 actin, beta-like 2
 55263
 0.14
chr19_48674183_48675124 0.65 C19orf68
 chromosome 19 open reading frame 68
 704
 0.32
chr10_100108984_100109336 0.63 ENSG00000221419
 .
 45904
 0.13
chr11_15178522_15178673 0.62 INSC
 inscuteable homolog (Drosophila)
 7943
 0.3
chr20_56622785_56622936 0.60 ENSG00000221385
 .
 19652
 0.22
chr3_98625022_98625173 0.59 ENSG00000207331
 .
 2206
 0.27
chr2_238215371_238215540 0.58 AC112715.2
 Uncharacterized protein
 49721
 0.15
chr11_130608199_130608484 0.56 C11orf44
 chromosome 11 open reading frame 44
 65490
 0.14
chr21_29827131_29827282 0.56 ENSG00000251894
 .
 288324
 0.01
chr20_3667221_3667372 0.55 ADAM33
 ADAM metallopeptidase domain 33
 4403
 0.16
chr14_75072847_75072998 0.55 LTBP2
 latent transforming growth factor beta binding protein 2
 5853
 0.22
chr18_10059619_10060204 0.54 ENSG00000263630
 .
 54717
 0.15
chr11_7912101_7912252 0.54 ENSG00000252769
 .
 1350
 0.35
chr8_119499700_119499851 0.54 SAMD12
 sterile alpha motif domain containing 12
 93346
 0.1
chr6_129507673_129507824 0.53 ENSG00000252554
 .
 250377
 0.02
chr11_74561444_74561595 0.53 ENSG00000242999
 .
 4564
 0.19
chr8_99021155_99021306 0.52 MATN2
 matrilin 2
 7542
 0.15
chr1_246150406_246150557 0.52 RP11-83A16.1
46372
 0.18
chr2_235934802_235934953 0.52 SH3BP4
 SH3-domain binding protein 4
 31393
 0.26
chr3_73835223_73835374 0.52 PDZRN3
 PDZ domain containing ring finger 3
 161207
 0.04
chr2_36657128_36657279 0.51 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 73589
 0.11
chr20_23148002_23148153 0.51 ENSG00000201527
 .
 6469
 0.24
chr14_68943525_68944196 0.51 RAD51B
 RAD51 paralog B
 65633
 0.13
chr11_14432940_14433091 0.50 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
 46963
 0.15
chr13_114872368_114872623 0.50 RASA3-IT1
 RASA3 intronic transcript 1 (non-protein coding)
 1800
 0.41
chr11_71698874_71699025 0.49 IL18BP
 interleukin 18 binding protein
 10638
 0.11
chr15_49015763_49015914 0.49 RP11-485O10.2
59549
 0.11
chr6_100716336_100716487 0.49 RP1-121G13.2
158583
 0.04
chr17_17780568_17780719 0.48 TOM1L2
 target of myb1-like 2 (chicken)
 5265
 0.19
chr9_101791785_101791940 0.47 TGFBR1
 transforming growth factor, beta receptor 1
 74458
 0.09
chr11_118492770_118493048 0.47 AP002954.3
14429
 0.11
chr1_44705174_44705804 0.47 ERI3-IT1
 ERI3 intronic transcript 1 (non-protein coding)
 4456
 0.21
chr8_141908612_141908763 0.47 PTK2
 protein tyrosine kinase 2
 7820
 0.26
chr2_232056745_232056896 0.47 ARMC9
 armadillo repeat containing 9
 6440
 0.22
chr1_170656810_170656961 0.46 PRRX1
 paired related homeobox 1
 23807
 0.25
chr2_19740386_19740537 0.46 OSR1
 odd-skipped related transciption factor 1
 182047
 0.03
chr1_21588856_21589397 0.46 RP3-329E20.2
3449
 0.23
chr2_151332991_151333142 0.46 RND3
 Rho family GTPase 3
 8830
 0.33
chr8_26519218_26519369 0.46 DPYSL2
 dihydropyrimidinase-like 2
 83372
 0.1
chr17_12630832_12630983 0.45 AC005358.1
4708
 0.2
chr10_69802673_69802824 0.45 HERC4
 HECT and RLD domain containing E3 ubiquitin protein ligase 4
 3024
 0.27
chr17_1683782_1683933 0.45 SERPINF1
 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
 8844
 0.12
chr9_117508350_117508501 0.45 TNFSF15
 tumor necrosis factor (ligand) superfamily, member 15
 45963
 0.14
chr13_98905870_98906021 0.45 RP11-573N10.1
20041
 0.17
chr15_99881623_99881774 0.45 AC022819.2
 Uncharacterized protein
 21870
 0.18
chr9_82379139_82379290 0.45 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 57533
 0.18
chr12_105812666_105812817 0.44 C12orf75
 chromosome 12 open reading frame 75
 88095
 0.08
chr10_80916996_80917718 0.44 ZMIZ1
 zinc finger, MIZ-type containing 1
 88565
 0.09
chr12_53474857_53475008 0.44 SPRYD3
 SPRY domain containing 3
 1728
 0.22
chr15_70668335_70668710 0.44 ENSG00000200216
 .
 182947
 0.03
chr7_151297671_151297822 0.44 PRKAG2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 31693
 0.18
chr3_134183959_134184110 0.44 CEP63
 centrosomal protein 63kDa
 20551
 0.16
chr11_44058607_44058758 0.43 ACCSL
 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like
 10849
 0.17
chr9_22040392_22040543 0.43 CDKN2B-AS1
 CDKN2B antisense RNA 1
 6283
 0.2
chr3_88856750_88856901 0.43 EPHA3
 EPH receptor A3
 299849
 0.01
chr22_27118545_27118696 0.43 CRYBA4
 crystallin, beta A4
 100692
 0.07
chrY_27544696_27544847 0.43 ENSG00000272042
 .
 60283
 0.14
chr6_144614901_144615052 0.43 UTRN
 utrophin
 2011
 0.42
chr19_42785461_42786111 0.43 CIC
 capicua transcriptional repressor
 2386
 0.14
chr4_89664108_89664259 0.43 FAM13A-AS1
 FAM13A antisense RNA 1
 21317
 0.18
chr8_95299657_95299808 0.43 GEM
 GTP binding protein overexpressed in skeletal muscle
 25154
 0.22
chrY_26417595_26417746 0.43 ENSG00000242425
 .
 60288
 0.14
chr15_78182901_78183238 0.42 CSPG4P13
 chondroitin sulfate proteoglycan 4 pseudogene 13
 3957
 0.18
chr12_6658690_6659153 0.42 IFFO1
 intermediate filament family orphan 1
 2145
 0.13
chr5_65072338_65072489 0.42 NLN
 neurolysin (metallopeptidase M3 family)
 4830
 0.27
chr14_52491686_52491966 0.42 NID2
 nidogen 2 (osteonidogen)
 13844
 0.16
chr21_28778719_28778870 0.42 ADAMTS5
 ADAM metallopeptidase with thrombospondin type 1 motif, 5
 439962
 0.01
chr8_95253991_95254142 0.42 GEM
 GTP binding protein overexpressed in skeletal muscle
 18932
 0.21
chr7_130012625_130012776 0.42 CPA1
 carboxypeptidase A1 (pancreatic)
 7480
 0.14
chr1_16343988_16344139 0.42 HSPB7
 heat shock 27kDa protein family, member 7 (cardiovascular)
 257
 0.86
chr9_130502702_130502853 0.42 TOR2A
 torsin family 2, member A
 5173
 0.1
chr9_89724167_89724318 0.42 C9orf170
 chromosome 9 open reading frame 170
 39317
 0.21
chr18_56247162_56247463 0.42 ENSG00000252284
 .
 20551
 0.14
chr6_136256944_136257095 0.41 ENSG00000238921
 .
 21126
 0.21
chr9_136271156_136271307 0.41 REXO4
 REX4, RNA exonuclease 4 homolog (S. cerevisiae)
 9789
 0.08
chr17_30662996_30663147 0.41 C17orf75
 chromosome 17 open reading frame 75
 690
 0.62
chr9_114706444_114706595 0.41 ENSG00000266315
 .
 12139
 0.2
chr17_48718114_48718630 0.41 ABCC3
 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
 6154
 0.13
chr14_58312690_58312841 0.41 ENSG00000252837
 .
 8387
 0.24
chr14_88937631_88937782 0.41 PTPN21
 protein tyrosine phosphatase, non-receptor type 21
 1746
 0.34
chr14_55057316_55057467 0.41 SAMD4A
 sterile alpha motif domain containing 4A
 22754
 0.22
chr1_27730071_27730579 0.40 GPR3
 G protein-coupled receptor 3
 11177
 0.13
chr1_157992444_157992595 0.39 KIRREL-IT1
 KIRREL intronic transcript 1 (non-protein coding)
 2821
 0.3
chr11_10345196_10345347 0.39 AMPD3
 adenosine monophosphate deaminase 3
 6053
 0.17
chr8_126582644_126582795 0.39 ENSG00000266452
 .
 125912
 0.06
chr17_66592514_66592665 0.39 FAM20A
 family with sequence similarity 20, member A
 4941
 0.26
chr1_214744112_214744263 0.39 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 19621
 0.24
chr15_85888485_85888636 0.39 AKAP13
 A kinase (PRKA) anchor protein 13
 35258
 0.15
chr1_120507427_120507715 0.39 RP5-1042I8.7
54335
 0.13
chr6_140364192_140364343 0.39 ENSG00000252107
 .
 115564
 0.07
chr10_33403329_33403717 0.39 ENSG00000263576
 .
 15959
 0.23
chr3_37154604_37154755 0.39 ENSG00000206645
 .
 19954
 0.15
chr2_73333310_73333461 0.39 RAB11FIP5
 RAB11 family interacting protein 5 (class I)
 6761
 0.18
chr15_74493564_74493715 0.39 STRA6
 stimulated by retinoic acid 6
 1152
 0.31
chr22_43709368_43709519 0.38 SCUBE1
 signal peptide, CUB domain, EGF-like 1
 29886
 0.16
chr12_50696750_50697016 0.38 AC140061.12
 Uncharacterized protein
 6394
 0.16
chr19_13127164_13127315 0.38 CTC-239J10.1
1914
 0.18
chr15_48845807_48845958 0.38 FBN1
 fibrillin 1
 92036
 0.08
chr12_93139497_93139648 0.38 PLEKHG7
 pleckstrin homology domain containing, family G (with RhoGef domain) member 7
 9261
 0.24
chr15_78598378_78598529 0.38 WDR61
 WD repeat domain 61
 6317
 0.13
chr16_53700893_53701044 0.38 RPGRIP1L
 RPGRIP1-like
 36754
 0.17
chr2_12191853_12192027 0.38 ENSG00000238503
 .
 21442
 0.26
chr16_70788132_70788283 0.38 VAC14-AS1
 VAC14 antisense RNA 1
 794
 0.57
chr7_81254412_81254563 0.38 HGF
 hepatocyte growth factor (hepapoietin A; scatter factor)
 137825
 0.05
chr17_70131143_70131294 0.38 SOX9
 SRY (sex determining region Y)-box 9
 14057
 0.3
chr5_53843408_53843569 0.37 SNX18
 sorting nexin 18
 29895
 0.23
chr15_59461408_59461559 0.37 ENSG00000253030
 .
 1978
 0.21
chr4_3709443_3709594 0.37 ADRA2C
 adrenoceptor alpha 2C
 58557
 0.14
chr7_55097499_55097650 0.37 EGFR
 epidermal growth factor receptor
 10763
 0.3
chr7_134483017_134483168 0.37 CALD1
 caldesmon 1
 18663
 0.27
chr19_41106420_41106924 0.37 LTBP4
 latent transforming growth factor beta binding protein 4
 605
 0.65
chr11_118475244_118475483 0.37 PHLDB1
 pleckstrin homology-like domain, family B, member 1
 1792
 0.23
chr7_107612741_107612892 0.37 ENSG00000238297
 .
 27611
 0.14
chr1_95484423_95484574 0.37 RP11-313A24.1
42654
 0.12
chr12_96040256_96040407 0.37 ENSG00000212448
 .
 28866
 0.2
chr6_158838381_158838532 0.37 RP11-732M18.2
18863
 0.2
chr6_107039846_107039997 0.37 ENSG00000200295
 .
 15670
 0.17
chr6_143444127_143444389 0.37 AIG1
 androgen-induced 1
 3129
 0.29
chr22_44453501_44453802 0.37 PARVB
 parvin, beta
 11290
 0.25
chr2_232675645_232675796 0.37 RP11-690I21.2
1164
 0.45
chr4_141177038_141177320 0.37 SCOC
 short coiled-coil protein
 1261
 0.51
chr12_102821294_102821445 0.37 IGF1
 insulin-like growth factor 1 (somatomedin C)
 51060
 0.17
chr2_46111015_46111315 0.36 PRKCE
 protein kinase C, epsilon
 116876
 0.06
chr16_70672907_70673058 0.36 IL34
 interleukin 34
 7486
 0.16
chr7_28076131_28076580 0.36 JAZF1
 JAZF zinc finger 1
 15937
 0.26
chr11_123074983_123075134 0.36 CLMP
 CXADR-like membrane protein
 9069
 0.2
chr13_50897665_50897816 0.36 ENSG00000221198
 .
 39633
 0.21
chr15_93571206_93571357 0.36 CHD2
 chromodomain helicase DNA binding protein 2
 19185
 0.22
chr6_133823044_133823328 0.36 RP3-323P13.2
9680
 0.25
chr8_123101555_123101706 0.36 HAS2-AS1
 HAS2 antisense RNA 1
 447954
 0.01
chr5_149539504_149539655 0.36 PDGFRB
 platelet-derived growth factor receptor, beta polypeptide
 4156
 0.17
chr18_42169234_42169525 0.36 SETBP1
 SET binding protein 1
 90759
 0.1
chr15_50152532_50152683 0.36 ATP8B4
 ATPase, class I, type 8B, member 4
 16285
 0.21
chr11_123060970_123061121 0.36 CTD-2216M2.1
1535
 0.4
chr2_28884288_28884439 0.36 AC074011.2
3043
 0.24
chr1_218549970_218550121 0.36 TGFB2
 transforming growth factor, beta 2
 30468
 0.19
chr11_19983976_19984127 0.36 NAV2-AS3
 NAV2 antisense RNA 3
 18832
 0.23
chr1_246024185_246024336 0.35 RP11-83A16.1
172593
 0.03
chr2_189980501_189980652 0.35 ENSG00000264725
 .
 17261
 0.2
chr10_79266628_79266779 0.35 ENSG00000199592
 .
 80104
 0.1
chr22_27908632_27908783 0.35 RP11-375H17.1
203761
 0.03
chr15_41335174_41335443 0.35 RP11-540O11.4
18611
 0.14
chr9_91610255_91610406 0.35 S1PR3
 sphingosine-1-phosphate receptor 3
 1091
 0.53
chr15_75993395_75993608 0.35 CSPG4
 chondroitin sulfate proteoglycan 4
 11688
 0.09
chr17_79534584_79534839 0.35 NPLOC4
 nuclear protein localization 4 homolog (S. cerevisiae)
 1050
 0.34
chr2_62376728_62376879 0.35 AC018462.2
2787
 0.26
chr1_212655450_212655601 0.35 NENF
 neudesin neurotrophic factor
 49296
 0.12
chr9_94533727_94534271 0.35 ENSG00000266855
 .
 135466
 0.05
chr11_28364524_28364785 0.35 ENSG00000222385
 .
 81588
 0.11
chr1_159891458_159892260 0.35 TAGLN2
 transgelin 2
 1648
 0.22
chr1_241645845_241645996 0.35 FH
 fumarate hydratase
 37141
 0.18
chr10_33418933_33419614 0.34 ENSG00000263576
 .
 31709
 0.18
chr6_5989927_5990321 0.34 NRN1
 neuritin 1
 17076
 0.23
chr6_44041464_44042348 0.34 RP5-1120P11.1
483
 0.79
chr20_17790847_17791092 0.34 ENSG00000221220
 .
 32258
 0.18
chr7_78912243_78912394 0.34 ENSG00000212482
 .
 60370
 0.15
chr6_75853034_75853185 0.34 COL12A1
 collagen, type XII, alpha 1
 8796
 0.28
chr14_55120501_55120684 0.34 SAMD4A
 sterile alpha motif domain containing 4A
 85955
 0.09
chr3_190812380_190812531 0.34 OSTN
 osteocrin
 104575
 0.07
chr2_226989431_226989582 0.34 ENSG00000263363
 .
 534003
 0.0
chr1_25132670_25132821 0.34 ENSG00000238482
 .
 28275
 0.19
chr6_46214251_46214402 0.34 ENPP5
 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
 75618
 0.1
chr7_91655297_91655448 0.34 AKAP9
 A kinase (PRKA) anchor protein 9
 44080
 0.16
chr5_140887145_140887296 0.34 PCDHGC5
 protocadherin gamma subfamily C, 5
 18412
 0.08
chr12_89842845_89842996 0.34 POC1B
 POC1 centriolar protein B
 48114
 0.13
chr9_132379434_132379585 0.34 C9orf50
 chromosome 9 open reading frame 50
 3546
 0.15
chr5_172225899_172226104 0.34 ENSG00000206741
 .
 18904
 0.13
chr14_31559795_31560006 0.34 AP4S1
 adaptor-related protein complex 4, sigma 1 subunit
 24398
 0.15
chr2_12957737_12958037 0.33 ENSG00000264370
 .
 80394
 0.11
chr2_196978823_196978974 0.33 RP11-347P5.1
37089
 0.15
chr7_116617261_116617412 0.33 AC106873.4
 Uncharacterized protein
 9810
 0.14
chr6_8084010_8084161 0.33 EEF1E1
 eukaryotic translation elongation factor 1 epsilon 1
 13459
 0.22
chr15_42444184_42444335 0.33 PLA2G4F
 phospholipase A2, group IVF
 4575
 0.18
chr7_25887678_25887829 0.33 ENSG00000199085
 .
 101853
 0.08
chr12_92594357_92594508 0.33 ENSG00000199895
 .
 30203
 0.17
chr1_157969918_157970069 0.33 KIRREL
 kin of IRRE like (Drosophila)
 6558
 0.23
chr5_168862994_168863145 0.33 ENSG00000206614
 .
 116384
 0.06
chr9_118090029_118090180 0.33 DEC1
 deleted in esophageal cancer 1
 186007
 0.03
chr10_79804314_79804465 0.33 RPS24
 ribosomal protein S24
 10748
 0.22
chr6_39521887_39522038 0.33 KIF6
 kinesin family member 6
 42074
 0.18
chr2_43497360_43497511 0.33 AC010883.5
40723
 0.17
chr1_119544917_119545068 0.33 TBX15
 T-box 15
 12813
 0.25
chr15_66212983_66213134 0.33 MEGF11
 multiple EGF-like-domains 11
 50500
 0.12
chr2_182813224_182813375 0.32 SSFA2
 sperm specific antigen 2
 27966
 0.17
chr22_39828056_39828207 0.32 MGAT3
 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
 25218
 0.12
chr11_10351462_10351613 0.32 AMPD3
 adenosine monophosphate deaminase 3
 12319
 0.16
chr16_20963780_20963931 0.32 LYRM1
 LYR motif containing 1
 51429
 0.11
chr8_97603049_97603490 0.32 SDC2
 syndecan 2
 4654
 0.31
chr10_101756595_101756746 0.32 DNMBP
 dynamin binding protein
 13006
 0.18
chr12_63077564_63077715 0.32 ENSG00000238475
 .
 32684
 0.17
chr19_13957559_13958184 0.32 ENSG00000207980
 .
 10398
 0.08
chr9_15999494_15999645 0.32 C9orf92
 chromosome 9 open reading frame 92
 216328
 0.02
chr1_18201641_18201961 0.32 ACTL8
 actin-like 8
 119993
 0.06
chr5_169143698_169143935 0.32 DOCK2
 dedicator of cytokinesis 2
 12863
 0.26
chr20_4044965_4045249 0.32 RP11-352D3.2
 Uncharacterized protein
 10705
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.1 0.2 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.4 GO:0060037 pharyngeal system development(GO:0060037)
0.1 0.2 GO:0030091 protein repair(GO:0030091)
0.1 0.2 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0031657 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.0 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.0 0.1 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.2 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0021508 floor plate formation(GO:0021508)
0.0 0.1 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0010713 negative regulation of collagen metabolic process(GO:0010713) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.0 GO:0009261 ribonucleotide catabolic process(GO:0009261)
0.0 0.5 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:2001279 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0035625 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.2 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.1 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0051593 response to folic acid(GO:0051593)
0.0 0.0 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.0 GO:0032610 interleukin-1 alpha production(GO:0032610)
0.0 0.2 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.0 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.0 GO:0010891 negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.2 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.0 GO:0072160 nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0017014 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.0 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.0 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.0 0.0 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0019883 antigen processing and presentation of endogenous antigen(GO:0019883)
0.0 0.1 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.0 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0032770 positive regulation of monooxygenase activity(GO:0032770)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.0 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.0 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0010225 response to UV-C(GO:0010225)
0.0 0.0 GO:0003181 atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.0 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0006385 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.1 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.0 GO:0071223 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0 0.0 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.0 GO:1904181 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.0 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.0 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.0 GO:0002178 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.0 GO:0060229 lipase activator activity(GO:0060229)
0.0 0.0 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.0 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.0 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation