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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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Results for ZBTB4

Z-value: 1.86

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Transcription factors associated with ZBTB4

Gene Symbol	Gene ID	Gene Info
ZBTB4 Ensembl NCBI GeneCards UniProt	ENSG00000174282.7	zinc finger and BTB domain containing 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_7386211_7386754	ZBTB4	1100	0.189315	0.82	7.0e-03	Click!
chr17_7383216_7383690	ZBTB4	609	0.401338	0.80	9.0e-03	Click!
chr17_7381423_7381951	ZBTB4	1157	0.209751	0.76	1.7e-02	Click!
chr17_7374867_7375018	ZBTB4	7902	0.061575	0.70	3.6e-02	Click!
chr17_7381091_7381327	ZBTB4	1635	0.142243	0.63	7.0e-02	Click!

Activity of the ZBTB4 motif across conditions

Conditions sorted by the z-value of the ZBTB4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr22_45065075_45065405	0.71	PRR5	proline rich 5 (renal)	647	0.75
chr11_60738679_60738857	0.66	CD6	CD6 molecule	347	0.79
chr1_207135548_207135879	0.58	FCAMR	Fc receptor, IgA, IgM, high affinity	7781	0.15
chr3_178867174_178867325	0.58	PIK3CA	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha	66	0.97
chr17_79201614_79201765	0.57	AC027601.1		818	0.43
chr16_50719380_50719617	0.56	SNX20	sorting nexin 20	4234	0.14
chr2_217039738_217039889	0.55	XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	65739	0.1
chr19_12892440_12892622	0.51	HOOK2	hook microtubule-tethering protein 2	3260	0.09
chr7_1052092_1052243	0.51	ENSG00000199023	.	10495	0.1
chr1_161041129_161041437	0.51	ARHGAP30	Rho GTPase activating protein 30	1523	0.18
chr2_143899228_143899449	0.51	ARHGAP15	Rho GTPase activating protein 15	12455	0.25
chr13_50017891_50018071	0.49	CAB39L	calcium binding protein 39-like	208	0.73
chr17_36877819_36877970	0.49	CTB-58E17.9		1369	0.17
chr22_50689372_50689523	0.49	HDAC10	histone deacetylase 10	14	0.94
chr19_1861829_1861998	0.48	KLF16	Kruppel-like factor 16	1654	0.17
chr19_16478953_16479699	0.47	EPS15L1	epidermal growth factor receptor pathway substrate 15-like 1	6562	0.16
chr1_169075983_169076134	0.47	ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide	497	0.77
chr16_50700983_50701245	0.47	RP11-401P9.5		992	0.45
chr11_67416249_67416400	0.46	ACY3	aspartoacylase (aminocyclase) 3	1270	0.29
chr10_82243155_82243396	0.46	TSPAN14	tetraspanin 14	24217	0.18
chr2_84881803_84881954	0.45	DNAH6	dynein, axonemal, heavy chain 6	3553	0.35
chr1_155046223_155046558	0.45	EFNA3	ephrin-A3	4958	0.08
chr1_89662683_89662979	0.45	GBP4	guanylate binding protein 4	1784	0.34
chrX_48335199_48335384	0.45	FTSJ1	FtsJ RNA methyltransferase homolog 1 (E. coli)	706	0.54
chr9_92074190_92074519	0.45	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	3486	0.3
chr11_60793831_60793982	0.44	CD6	CD6 molecule	17900	0.14
chr14_93125473_93125733	0.44	RIN3	Ras and Rab interactor 3	6757	0.28
chr7_91763622_91763773	0.42	CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1	147	0.6
chr22_38239565_38239763	0.42	ANKRD54	ankyrin repeat domain 54	225	0.76
chr11_961322_961473	0.42	ENSG00000264671	.	10033	0.12
chr17_80187474_80187768	0.41	SLC16A3	solute carrier family 16 (monocarboxylate transporter), member 3	652	0.55
chr3_157823305_157823481	0.41	RSRC1	arginine/serine-rich coiled-coil 1	251	0.57
chr6_45462270_45462479	0.41	RUNX2	runt-related transcription factor 2	72152	0.11
chr7_2550731_2550882	0.41	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	1357	0.38
chr12_68768030_68768260	0.40	MDM1	Mdm1 nuclear protein homolog (mouse)	41984	0.19
chr1_200857986_200858333	0.40	C1orf106	chromosome 1 open reading frame 106	2017	0.3
chr2_25558574_25558742	0.40	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	6096	0.22
chr16_1696942_1697215	0.40	CRAMP1L	Crm, cramped-like (Drosophila)	8835	0.1
chr3_52238534_52238685	0.40	ALAS1	aminolevulinate, delta-, synthase 1	2039	0.2
chr1_48693883_48694034	0.40	RP5-1024N4.4		1275	0.5
chr1_200988982_200989289	0.40	KIF21B	kinesin family member 21B	3401	0.24
chr11_117694194_117694498	0.39	FXYD2	FXYD domain containing ion transport regulator 2	1113	0.39
chr5_177642302_177642563	0.39	HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B	10860	0.18
chr9_135037005_135037156	0.39	NTNG2	netrin G2	254	0.94
chr2_144694755_144694906	0.38	AC016910.1		190	0.96
chr15_91126847_91126998	0.38	CRTC3	CREB regulated transcription coactivator 3	10023	0.16
chr3_43339392_43339567	0.38	SNRK	SNF related kinase	11401	0.18
chr5_171586076_171586262	0.38	STK10	serine/threonine kinase 10	29221	0.16
chr1_221909737_221909888	0.38	DUSP10	dual specificity phosphatase 10	990	0.71
chr1_154976091_154976266	0.38	ZBTB7B	zinc finger and BTB domain containing 7B	883	0.32
chr9_92110162_92110545	0.38	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	1994	0.34
chr4_99849491_99849642	0.38	RP11-571L19.7		482	0.52
chr6_160109062_160109319	0.37	SOD2	superoxide dismutase 2, mitochondrial	5070	0.19
chr1_25322027_25322178	0.37	ENSG00000264371	.	27892	0.16
chr4_154438949_154439100	0.37	KIAA0922	KIAA0922	38024	0.19
chr12_57940094_57940304	0.37	DCTN2	dynactin 2 (p50)	705	0.42
chr8_66861197_66861965	0.37	DNAJC5B	DnaJ (Hsp40) homolog, subfamily C, member 5 beta	72214	0.11
chr22_40857221_40857372	0.37	MKL1	megakaryoblastic leukemia (translocation) 1	2126	0.3
chr3_12943997_12944148	0.36	AC034198.7		51914	0.1
chr9_92094224_92094387	0.36	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	500	0.84
chr13_112037455_112037671	0.36	TEX29	testis expressed 29	64548	0.14
chr17_80839258_80839409	0.36	TBCD	tubulin folding cofactor D	2695	0.26
chr15_91446650_91446801	0.36	MAN2A2	mannosidase, alpha, class 2A, member 2	249	0.84
chr14_69446329_69446480	0.36	ACTN1-AS1	ACTN1 antisense RNA 1	5	0.78
chr9_86321400_86321693	0.36	RP11-522I20.3		963	0.39
chr17_39836456_39836610	0.36	EIF1	eukaryotic translation initiation factor 1	8606	0.11
chr2_231741597_231741748	0.36	AC012507.3		9543	0.16
chr21_19156734_19157011	0.36	AL109761.5		8933	0.24
chr3_22511575_22511726	0.35	ENSG00000221384	.	640420	0.0
chr19_48112417_48112568	0.35	GLTSCR1	glioma tumor suppressor candidate region gene 1	112	0.95
chr5_133303783_133303941	0.35	C5orf15	chromosome 5 open reading frame 15	616	0.79
chr12_120445548_120445820	0.35	CCDC64	coiled-coil domain containing 64	18011	0.19
chr11_114271994_114272294	0.35	RBM7	RNA binding motif protein 7	748	0.46
chr17_20601642_20602055	0.35	AC126365.1		17948	0.23
chr22_27043526_27043866	0.35	CRYBA4	crystallin, beta A4	25768	0.16
chr1_100862289_100862440	0.35	ENSG00000216067	.	18033	0.19
chr13_99930195_99930450	0.35	GPR18	G protein-coupled receptor 18	16324	0.18
chr20_24371098_24371253	0.35	SYNDIG1	synapse differentiation inducing 1	78660	0.11
chr11_6494712_6494947	0.35	TRIM3	tripartite motif containing 3	261	0.86
chr13_103425200_103425393	0.35	TEX30	testis expressed 30	809	0.5
chr3_47404358_47404541	0.34	RP11-708J19.1		18040	0.15
chr5_157038541_157038692	0.34	ENSG00000252068	.	32111	0.11
chr11_64567406_64567557	0.34	MAP4K2	mitogen-activated protein kinase kinase kinase kinase 2	3166	0.15
chr2_26990880_26991100	0.34	SLC35F6	solute carrier family 35, member F6	3833	0.21
chr8_65492231_65492382	0.34	BHLHE22	basic helix-loop-helix family, member e22	508	0.8
chr3_56923038_56923523	0.34	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	27219	0.21
chr11_128390493_128390655	0.34	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	1522	0.45
chr18_13135857_13136037	0.34	RP11-794M8.1		80377	0.08
chr15_91400154_91400352	0.34	ENSG00000241869	.	816	0.47
chr1_2516385_2516615	0.34	FAM213B	family with sequence similarity 213, member B	1714	0.21
chr19_40336344_40336545	0.33	FBL	fibrillarin	525	0.75
chr2_241497025_241497176	0.33	ANKMY1	ankyrin repeat and MYND domain containing 1	279	0.85
chr13_99861573_99861726	0.33	ENSG00000201793	.	3687	0.23
chr3_128353247_128353398	0.33	RPN1	ribophorin I	16370	0.19
chr10_128076889_128077040	0.33	ADAM12	ADAM metallopeptidase domain 12	60	0.99
chr12_7061247_7061398	0.33	PTPN6	protein tyrosine phosphatase, non-receptor type 6	784	0.32
chr16_68404284_68404435	0.33	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	549	0.68
chr14_75713523_75713674	0.33	RP11-293M10.2		12516	0.15
chr5_176865644_176865800	0.33	PRR7-AS1	PRR7 antisense RNA 1	5756	0.1
chr6_24719020_24719350	0.33	C6orf62	chromosome 6 open reading frame 62	1041	0.43
chr3_9773831_9773982	0.33	BRPF1	bromodomain and PHD finger containing, 1	258	0.86
chr1_9008541_9008747	0.33	CA6	carbonic anhydrase VI	2698	0.23
chr19_6552264_6552452	0.32	ENSG00000199223	.	20710	0.1
chr18_2570804_2570955	0.32	METTL4	methyltransferase like 4	353	0.65
chr7_105315027_105315339	0.32	ATXN7L1	ataxin 7-like 1	4426	0.3
chrX_128906184_128906456	0.32	SASH3	SAM and SH3 domain containing 3	7640	0.2
chr1_161160490_161160641	0.32	ADAMTS4	ADAM metallopeptidase with thrombospondin type 1 motif, 4	8278	0.06
chr3_60013094_60013245	0.32	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	55586	0.18
chr13_114923595_114923825	0.32	RASA3	RAS p21 protein activator 3	25624	0.18
chr2_235396870_235397178	0.32	ARL4C	ADP-ribosylation factor-like 4C	8220	0.33
chr2_68944719_68944882	0.32	ARHGAP25	Rho GTPase activating protein 25	7166	0.26
chr9_95726154_95726351	0.32	FGD3	FYVE, RhoGEF and PH domain containing 3	9	0.98
chr11_43965052_43965302	0.31	C11orf96	chromosome 11 open reading frame 96	1122	0.46
chr1_160602079_160602495	0.31	SLAMF1	signaling lymphocytic activation molecule family member 1	14524	0.15
chr19_6836515_6836666	0.31	EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	50987	0.08
chr11_128494791_128495096	0.31	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	37490	0.15
chr4_90230994_90231213	0.31	GPRIN3	GPRIN family member 3	1942	0.49
chr15_70005461_70005680	0.31	ENSG00000238870	.	17591	0.25
chr14_22962932_22963083	0.31	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	6836	0.11
chr12_8086752_8086984	0.31	SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	1914	0.28
chr10_35416607_35416758	0.31	CREM	cAMP responsive element modulator	277	0.76
chr22_28414851_28415002	0.31	ENSG00000235954	.	21361	0.17
chr16_23970694_23970937	0.31	PRKCB	protein kinase C, beta	122271	0.05
chr9_36457997_36458148	0.31	RNF38	ring finger protein 38	56877	0.14
chr10_75492270_75492421	0.31	GLUD1P3	glutamate dehydrogenase 1 pseudogene 3	1411	0.22
chr16_27358317_27358543	0.31	IL4R	interleukin 4 receptor	2201	0.34
chr6_18504116_18504412	0.31	ENSG00000207775	.	67751	0.12
chr5_171542288_171542655	0.31	ENSG00000266671	.	34491	0.16
chr8_56831288_56831439	0.31	ENSG00000216204	.	9843	0.14
chr1_25970325_25970699	0.30	RP1-187B23.1		15090	0.18
chr10_43828284_43828565	0.30	ENSG00000221468	.	8810	0.19
chr20_31560402_31560699	0.30	EFCAB8	EF-hand calcium binding domain 8	12899	0.15
chr17_38508527_38508765	0.30	RARA	retinoic acid receptor, alpha	7153	0.1
chr6_41165913_41166064	0.30	TREML2	triggering receptor expressed on myeloid cells-like 2	2944	0.17
chr3_195854450_195854849	0.30	TFRC	transferrin receptor	45589	0.11
chr6_168106937_168107158	0.30	AL009178.1	Uncharacterized protein; cDNA FLJ43200 fis, clone FEBRA2007793	89163	0.09
chr16_85970689_85970881	0.30	IRF8	interferon regulatory factor 8	22866	0.22
chr17_43312253_43312446	0.30	FMNL1	formin-like 1	6093	0.1
chr7_150445905_150446107	0.30	GIMAP5	GTPase, IMAP family member 5	11570	0.15
chr8_27262021_27262365	0.30	PTK2B	protein tyrosine kinase 2 beta	7224	0.24
chr14_92588920_92589227	0.30	CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	757	0.42
chr2_223520560_223520711	0.30	FARSB	phenylalanyl-tRNA synthetase, beta subunit	135	0.96
chr3_55520600_55520901	0.30	WNT5A	wingless-type MMTV integration site family, member 5A	581	0.64
chr1_167640654_167640873	0.30	RP3-455J7.4		40852	0.14
chr5_134210758_134211123	0.30	TXNDC15	thioredoxin domain containing 15	92	0.96
chr3_196668934_196669213	0.30	NCBP2	nuclear cap binding protein subunit 2, 20kDa	175	0.91
chr16_66886913_66887064	0.30	RP11-61A14.1		363	0.79
chr5_92915769_92915920	0.29	ENSG00000237187	.	869	0.61
chr1_9778118_9778444	0.29	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	154	0.95
chr7_100815057_100815252	0.29	VGF	VGF nerve growth factor inducible	6280	0.1
chr1_3513905_3514101	0.29	MEGF6	multiple EGF-like-domains 6	14056	0.13
chr3_185903313_185903553	0.29	ETV5	ets variant 5	75326	0.1
chr12_54700699_54700954	0.29	COPZ1	coatomer protein complex, subunit zeta 1	5840	0.08
chr4_11484224_11484375	0.29	HS3ST1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	52910	0.16
chr1_155025661_155025992	0.29	ADAM15	ADAM metallopeptidase domain 15	1998	0.14
chr11_62623043_62623194	0.29	ENSG00000255717	.	16	0.84
chr17_19411306_19411486	0.29	SLC47A1	solute carrier family 47 (multidrug and toxin extrusion), member 1	25379	0.13
chr22_24833138_24833289	0.29	ADORA2A	adenosine A2a receptor	4405	0.21
chr22_30671598_30671900	0.29	OSM	oncostatin M	8920	0.1
chr20_43149949_43150100	0.29	SERINC3	serine incorporator 3	627	0.65
chr3_130573085_130573236	0.29	ATP2C1	ATPase, Ca++ transporting, type 2C, member 1	3547	0.26
chr17_20180363_20180514	0.29	ENSG00000252971	.	13132	0.17
chr3_108012757_108013257	0.29	HHLA2	HERV-H LTR-associating 2	2369	0.35
chr1_36629241_36629392	0.29	MAP7D1	MAP7 domain containing 1	6500	0.15
chr12_4548204_4548355	0.29	FGF6	fibroblast growth factor 6	5106	0.24
chr6_106925994_106926145	0.29	ENSG00000200314	.	23366	0.15
chr10_119303450_119303630	0.29	EMX2	empty spiracles homeobox 2	1031	0.41
chr9_20424911_20425071	0.29	ENSG00000222202	.	6672	0.2
chr3_31273885_31274070	0.29	ENSG00000222983	.	3770	0.34
chr9_134148721_134148919	0.29	FAM78A	family with sequence similarity 78, member A	2910	0.24
chr7_117854704_117854855	0.28	ANKRD7	ankyrin repeat domain 7	9933	0.26
chr1_167421985_167422136	0.28	RP11-104L21.2		5838	0.24
chr4_77930193_77930344	0.28	SEPT11	septin 11	11417	0.23
chr2_235348946_235349177	0.28	ARL4C	ADP-ribosylation factor-like 4C	56183	0.17
chr10_126347590_126347883	0.28	FAM53B-AS1	FAM53B antisense RNA 1	44458	0.15
chr2_131798429_131798580	0.28	ARHGEF4	Rho guanine nucleotide exchange factor (GEF) 4	346	0.9
chr3_129295607_129295852	0.28	PLXND1	plexin D1	12641	0.15
chr7_106668406_106668557	0.28	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	16613	0.23
chr19_17488996_17489147	0.28	PLVAP	plasmalemma vesicle associated protein	912	0.35
chr11_35068566_35068760	0.28	PDHX	pyruvate dehydrogenase complex, component X	69332	0.09
chr13_111833278_111833429	0.28	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	3932	0.25
chr8_142386929_142387080	0.28	GPR20	G protein-coupled receptor 20	9637	0.12
chr8_66210348_66210499	0.28	ENSG00000200714	.	294543	0.01
chr4_25238539_25238850	0.28	PI4K2B	phosphatidylinositol 4-kinase type 2 beta	3097	0.32
chr7_30198730_30198946	0.28	AC007036.5		1691	0.34
chr12_6929592_6929743	0.28	GPR162	G protein-coupled receptor 162	1044	0.27
chr10_129100878_129101155	0.28	FAM196A	family with sequence similarity 196, member A	106594	0.08
chr5_61883696_61884006	0.28	LRRC70	leucine rich repeat containing 70	9149	0.22
chr1_41894473_41894635	0.27	ENSG00000252563	.	38145	0.15
chr16_1979596_1979747	0.27	HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	11230	0.06
chr17_64485644_64485795	0.27	RP11-4F22.2		72747	0.1
chr19_1026975_1027253	0.27	CNN2	calponin 2	424	0.64
chr15_70040588_70040739	0.27	ENSG00000238870	.	17502	0.23
chr16_23990918_23991069	0.27	PRKCB	protein kinase C, beta	142449	0.04
chr22_45809669_45809983	0.27	RIBC2	RIB43A domain with coiled-coils 2	252	0.57
chr17_78711898_78712101	0.27	RP11-28G8.1		67433	0.11
chr7_107642984_107643179	0.27	LAMB1	laminin, beta 1	524	0.74
chr8_26435918_26436069	0.27	DPYSL2	dihydropyrimidinase-like 2	72	0.98
chr8_144655938_144656162	0.27	RP11-661A12.9		390	0.57
chrX_54835704_54835922	0.27	MAGED2	melanoma antigen family D, 2	320	0.88

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.1	GO:0072110	glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124)
0.1	0.3	GO:0001714	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.3	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.4	GO:0090281	negative regulation of calcium ion import(GO:0090281)
0.1	0.5	GO:0072203	cell proliferation involved in metanephros development(GO:0072203)
0.1	0.3	GO:0031167	rRNA methylation(GO:0031167)
0.1	0.4	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.3	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.1	0.2	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.1	1.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.1	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1	0.3	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.3	GO:0032661	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1	0.2	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.1	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.3	GO:0060080	inhibitory postsynaptic potential(GO:0060080)
0.1	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.1	0.2	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.3	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.1	0.4	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.1	0.2	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.3	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.3	GO:0016265	obsolete death(GO:0016265)
0.1	0.2	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.1	0.4	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.1	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.0	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.0	GO:0000154	rRNA modification(GO:0000154)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.2	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.2	GO:0015705	iodide transport(GO:0015705)
0.0	0.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.2	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.2	GO:0046666	retinal cell programmed cell death(GO:0046666)
0.0	0.2	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.3	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:1903727	positive regulation of phospholipid metabolic process(GO:1903727)
0.0	0.0	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.2	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.2	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.3	GO:0051957	positive regulation of amino acid transport(GO:0051957)
0.0	0.1	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.2	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.2	GO:0046645	regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.2	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.2	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.3	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.3	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0010985	negative regulation of lipoprotein particle clearance(GO:0010985)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.2	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.0	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.1	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.0	GO:0090185	negative regulation of kidney development(GO:0090185)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.0	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.2	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.3	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.2	GO:0051299	centrosome separation(GO:0051299)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0032682	negative regulation of chemokine production(GO:0032682)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0051665	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.0	0.5	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.3	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.1	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.2	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.0	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0072283	mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003337) metanephric renal vesicle morphogenesis(GO:0072283)
0.0	0.1	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.0	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.0	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.2	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.2	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.0	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.1	GO:0001562	response to protozoan(GO:0001562) defense response to protozoan(GO:0042832)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.2	GO:0006911	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.2	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0098900	regulation of action potential(GO:0098900)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0032026	response to magnesium ion(GO:0032026)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.5	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.7	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.3	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.0	GO:0048680	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.1	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.2	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0045354	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0	0.0	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.0	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.0	0.0	GO:0046471	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.2	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.2	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.0	GO:0071698	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.4	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.0	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.1	GO:0042761	very long-chain fatty acid biosynthetic process(GO:0042761)
0.0	0.0	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.0	GO:0090224	regulation of spindle organization(GO:0090224)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.2	GO:0010039	response to iron ion(GO:0010039)
0.0	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.2	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.5	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0070977	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0	0.1	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.4	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0034145	regulation of toll-like receptor 3 signaling pathway(GO:0034139) positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.2	GO:0010458	exit from mitosis(GO:0010458)
0.0	0.0	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.1	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.0	0.1	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.0	GO:0010755	regulation of plasminogen activation(GO:0010755)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0048710	regulation of astrocyte differentiation(GO:0048710)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.0	0.1	GO:0001706	endoderm formation(GO:0001706)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0034311	diol metabolic process(GO:0034311)
0.0	0.1	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:1904590	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.0	0.1	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.0	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.0	GO:0006684	sphingomyelin metabolic process(GO:0006684)
0.0	0.0	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0000270	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0051531	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.5	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.0	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	0.2	GO:0034453	microtubule anchoring(GO:0034453)
0.0	0.0	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.2	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336) long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0	0.1	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.0	0.1	GO:0045911	positive regulation of isotype switching(GO:0045830) positive regulation of DNA recombination(GO:0045911)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.0	GO:0043620	regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0009820	alkaloid metabolic process(GO:0009820)
0.0	0.0	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.0	GO:0031060	regulation of histone methylation(GO:0031060)
0.0	0.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:1904181	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.0	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.4	GO:0030183	B cell differentiation(GO:0030183)
0.0	0.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.2	GO:0045730	respiratory burst(GO:0045730)
0.0	0.0	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.1	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.3	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.0	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.1	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0032411	positive regulation of transporter activity(GO:0032411)
0.0	0.0	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0043525	positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:0043536	positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0	0.1	GO:0072148	epithelial cell fate commitment(GO:0072148)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0034433	steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0	0.7	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0010923	negative regulation of phosphatase activity(GO:0010923) negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.0	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.4	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.0	GO:0046881	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.0	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.0	GO:0034143	regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.0	0.1	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.0	GO:0003351	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.4	GO:0051318	G1 phase(GO:0051318)
0.0	0.0	GO:0045840	positive regulation of mitotic nuclear division(GO:0045840) positive regulation of nuclear division(GO:0051785)
0.0	0.0	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.0	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.1	GO:0031670	cellular response to nutrient(GO:0031670)
0.0	0.4	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.1	GO:0032105	negative regulation of response to extracellular stimulus(GO:0032105) negative regulation of response to nutrient levels(GO:0032108)
0.0	0.1	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0042596	fear response(GO:0042596)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.0	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.0	GO:0030540	female genitalia development(GO:0030540)
0.0	0.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.0	GO:0001510	RNA methylation(GO:0001510)
0.0	0.0	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.6	GO:0071166	ribonucleoprotein complex localization(GO:0071166)
0.0	0.1	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching(GO:0060678)
0.0	0.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.1	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.3	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.0	GO:0010759	positive regulation of macrophage chemotaxis(GO:0010759) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0045075	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0060561	apoptotic process involved in morphogenesis(GO:0060561)
0.0	0.0	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.0	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.0	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.1	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.0	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.0	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.0	GO:0002524	hypersensitivity(GO:0002524) regulation of acute inflammatory response to antigenic stimulus(GO:0002864) regulation of hypersensitivity(GO:0002883)
0.0	0.0	GO:1902743	regulation of lamellipodium organization(GO:1902743)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0051852	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0	0.1	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.0	0.2	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0051608	histamine transport(GO:0051608)
0.0	0.0	GO:0051881	regulation of mitochondrial membrane potential(GO:0051881)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.2	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.0	GO:0045988	negative regulation of striated muscle contraction(GO:0045988)
0.0	0.0	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.2	GO:0001836	release of cytochrome c from mitochondria(GO:0001836)
0.0	0.0	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.0	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.0	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.2	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.3	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0042094	interleukin-2 biosynthetic process(GO:0042094)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.3	GO:0050680	negative regulation of epithelial cell proliferation(GO:0050680)
0.0	0.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.0	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.0	GO:1904936	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.1	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.0	GO:0032817	regulation of natural killer cell proliferation(GO:0032817)
0.0	0.0	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.0	GO:0001774	microglial cell activation(GO:0001774)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.0	0.0	GO:0042482	positive regulation of odontogenesis(GO:0042482) positive regulation of tooth mineralization(GO:0070172)
0.0	0.4	GO:1902653	secondary alcohol biosynthetic process(GO:1902653)
0.0	0.1	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.1	GO:0050927	positive regulation of positive chemotaxis(GO:0050927)
0.0	0.0	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.3	GO:0000724	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0	0.0	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911) negative regulation of cell killing(GO:0031342)
0.0	0.1	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.1	GO:0060716	labyrinthine layer blood vessel development(GO:0060716)
0.0	0.0	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.0	GO:0036230	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0	0.0	GO:0016048	detection of temperature stimulus(GO:0016048)
0.0	0.0	GO:0046949	fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0	0.7	GO:0007173	epidermal growth factor receptor signaling pathway(GO:0007173) ERBB signaling pathway(GO:0038127)
0.0	0.0	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0045683	negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of keratinocyte differentiation(GO:0045617) negative regulation of epidermis development(GO:0045683)
0.0	0.0	GO:0051452	intracellular pH reduction(GO:0051452)
0.0	0.0	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0051225	spindle assembly(GO:0051225)
0.0	0.0	GO:0032461	regulation of protein oligomerization(GO:0032459) positive regulation of protein oligomerization(GO:0032461)
0.0	0.6	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.0	GO:0061647	histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0	0.7	GO:0008033	tRNA processing(GO:0008033)
0.0	0.1	GO:0042355	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.0	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.2	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0015893	drug transport(GO:0015893)
0.0	0.0	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.1	GO:0048008	platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0	0.0	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.0	GO:0050951	sensory perception of temperature stimulus(GO:0050951)
0.0	0.1	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0000076	DNA replication checkpoint(GO:0000076)
0.0	0.0	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.0	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.0	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.0	GO:0001820	serotonin secretion(GO:0001820)
0.0	0.0	GO:0015865	purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.0	0.1	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.0	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0060900	optic cup morphogenesis involved in camera-type eye development(GO:0002072) embryonic camera-type eye formation(GO:0060900)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.0	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.1	GO:0001964	startle response(GO:0001964)
0.0	0.0	GO:0072273	metanephric nephron morphogenesis(GO:0072273)
0.0	0.0	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.0	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.4	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.1	0.4	GO:0070938	contractile ring(GO:0070938)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0032133	chromosome passenger complex(GO:0032133)
0.1	0.3	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	0.3	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.6	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1	0.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.2	GO:0001940	male pronucleus(GO:0001940)
0.1	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.1	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.4	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.8	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.3	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.2	GO:0000346	transcription export complex(GO:0000346)
0.0	0.2	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.9	GO:0030175	filopodium(GO:0030175)
0.0	0.2	GO:0001741	XY body(GO:0001741)
0.0	0.2	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.3	GO:0042581	specific granule(GO:0042581)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.3	GO:0030313	cell envelope(GO:0030313)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.0	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.0	GO:0038201	TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.0	0.0	GO:0001939	female pronucleus(GO:0001939)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.4	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.3	GO:0005844	polysome(GO:0005844)
0.0	0.5	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.4	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.2	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.0	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.3	GO:0043195	terminal bouton(GO:0043195)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.3	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.0	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.0	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0099738	cell cortex region(GO:0099738)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.0	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.2	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.0	0.3	GO:0042641	actomyosin(GO:0042641)
0.0	0.0	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.0	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.0	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.0	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	1.3	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.3	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.4	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.7	GO:0098562	cytoplasmic side of membrane(GO:0098562)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.0	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.4	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.3	GO:0005758	mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.2	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.1	0.2	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1	0.2	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.5	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	0.2	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.2	GO:0005113	patched binding(GO:0005113)
0.1	0.3	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	0.3	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.2	GO:0016748	succinyltransferase activity(GO:0016748)
0.1	0.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.1	0.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.2	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.1	0.2	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	0.5	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.6	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.2	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.2	GO:0052743	inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.3	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.4	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.4	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.4	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0052745	inositol phosphate phosphatase activity(GO:0052745)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.5	GO:0032451	demethylase activity(GO:0032451)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.5	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.3	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.2	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.3	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0004950	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.2	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.0	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.0	GO:0017136	NAD-dependent histone deacetylase activity(GO:0017136)
0.0	0.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.2	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.0	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	1.3	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.3	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0016208	AMP binding(GO:0016208)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.3	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.8	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.2	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.0	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0005351	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0	0.3	GO:0001104	transcription factor activity, RNA polymerase II transcription factor binding(GO:0001076) RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.3	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.5	GO:0019903	protein phosphatase binding(GO:0019903)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.2	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.0	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.5	GO:0004896	cytokine receptor activity(GO:0004896)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.4	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.2	GO:0051117	ATPase binding(GO:0051117)
0.0	0.1	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.3	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.2	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.1	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114) 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	1.0	GO:0017124	SH3 domain binding(GO:0017124)
0.0	0.0	GO:0001848	complement binding(GO:0001848)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.0	GO:0031432	titin binding(GO:0031432)
0.0	0.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.2	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.0	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.0	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0010851	cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.0	0.0	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.8	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.0	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.0	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.5	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.9	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	1.8	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.8	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.3	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.4	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.7	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.2	PID EPO PATHWAY	EPO signaling pathway
0.0	0.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.8	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.3	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.1	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.8	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.5	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.0	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.1	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.3	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.3	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.4	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.5	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.0	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.4	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.1	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.1	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.2	PID TELOMERASE PATHWAY	Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.1	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	0.6	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.7	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.7	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.5	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.6	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.3	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	1.3	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.0	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.0	0.4	REACTOME IL 2 SIGNALING	Genes involved in Interleukin-2 signaling
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.3	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.0	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.2	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.1	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.4	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.7	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.6	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	1.0	REACTOME TOLL RECEPTOR CASCADES	Genes involved in Toll Receptor Cascades
0.0	0.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.7	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.0	0.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.3	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.2	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.2	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.3	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.0	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.5	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.2	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.1	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)

Results for ZBTB4

Z-value: 1.86

Motif logo

Transcription factors associated with ZBTB4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ZBTB4 motif across conditions

Conditions sorted by the z-value of the ZBTB4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: