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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZBTB7A_ZBTB7C

Z-value: 2.09

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Transcription factors associated with ZBTB7A_ZBTB7C

Gene Symbol	Gene ID	Gene Info
ZBTB7A Ensembl NCBI GeneCards UniProt	ENSG00000178951.4	ZBTB7A
ZBTB7C Ensembl NCBI GeneCards UniProt	ENSG00000184828.5	ZBTB7C

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ZBTB7A	chr19_4064373_4064526	1281	0.277002	0.92	4.3e-04	Click!
ZBTB7A	chr19_4082277_4082468	15429	0.106401	0.92	5.4e-04	Click!
ZBTB7A	chr19_4066977_4067128	109	0.940558	0.85	4.0e-03	Click!
ZBTB7A	chr19_4078452_4078630	11598	0.110801	0.82	7.0e-03	Click!
ZBTB7A	chr19_4066237_4066388	582	0.614101	0.80	1.0e-02	Click!
ZBTB7C	chr18_45936153_45936382	474	0.838729	0.96	6.1e-05	Click!
ZBTB7C	chr18_45534337_45534541	33055	0.208461	0.93	2.8e-04	Click!
ZBTB7C	chr18_45688335_45688486	3292	0.286891	0.91	6.7e-04	Click!
ZBTB7C	chr18_45663037_45663235	596	0.806858	0.89	1.2e-03	Click!
ZBTB7C	chr18_45935563_45935714	25	0.981451	0.87	2.2e-03	Click!

Activity of the ZBTB7A_ZBTB7C motif across conditions

Conditions sorted by the z-value of the ZBTB7A_ZBTB7C motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_140772630_140772870	0.94	TMEM178B	transmembrane protein 178B	1282	0.5
chr15_33487170_33487350	0.93	FMN1	formin 1	363	0.92
chr16_57199787_57199938	0.87	FAM192A	family with sequence similarity 192, member A	7838	0.15
chr7_37960937_37961095	0.85	EPDR1	ependymin related 1	94	0.97
chr8_145731715_145731866	0.85	ENSG00000255182	.	963	0.24
chr8_144976835_144977223	0.82	PLEC	plectin	24150	0.09
chr22_50907441_50907726	0.80	SBF1	SET binding factor 1	5788	0.09
chr10_122216941_122217092	0.79	PPAPDC1A	phosphatidic acid phosphatase type 2 domain containing 1A	257	0.94
chr3_14482734_14482908	0.79	SLC6A6	solute carrier family 6 (neurotransmitter transporter), member 6	8643	0.24
chr1_180123457_180123608	0.76	QSOX1	quiescin Q6 sulfhydryl oxidase 1	437	0.87
chr22_19435389_19435540	0.73	AC000068.5		48	0.6
chrX_53118423_53118574	0.69	TSPYL2	TSPY-like 2	6935	0.19
chr13_41239473_41239624	0.67	FOXO1	forkhead box O1	1186	0.56
chr7_66147471_66147622	0.63	RP4-756H11.3		27973	0.16
chr6_87865528_87865679	0.62	ZNF292	zinc finger protein 292	264	0.76
chr4_56212156_56212324	0.59	SRD5A3	steroid 5 alpha-reductase 3	36	0.98
chr2_128990579_128990730	0.58	UGGT1	UDP-glucose glycoprotein glucosyltransferase 1	53294	0.14
chr6_28602727_28602878	0.58	ENSG00000272278	.	13240	0.2
chr1_10651223_10651374	0.57	ENSG00000243267	.	25595	0.16
chrX_55516093_55516244	0.57	USP51	ubiquitin specific peptidase 51	533	0.8
chr10_71390210_71390493	0.56	C10orf35	chromosome 10 open reading frame 35	51	0.98
chr17_77966270_77966521	0.55	CTD-2529O21.1		245	0.85
chr5_141348457_141348608	0.54	RNF14	ring finger protein 14	72	0.96
chr1_2210385_2210536	0.53	RP4-713A8.1		47672	0.08
chr17_78261654_78261965	0.53	RNF213	ring finger protein 213	27140	0.13
chr10_52834025_52834306	0.53	PRKG1	protein kinase, cGMP-dependent, type I	231	0.94
chr8_495904_496055	0.52	TDRP	testis development related protein	198	0.96
chr8_27471547_27471716	0.51	CLU	clusterin	129	0.96
chr22_17588430_17588590	0.51	CECR6	cat eye syndrome chromosome region, candidate 6	13633	0.14
chr1_205744099_205744250	0.51	RAB7L1	RAB7, member RAS oncogene family-like 1	187	0.93
chrX_68384913_68385097	0.51	PJA1	praja ring finger 1, E3 ubiquitin protein ligase	275	0.96
chr2_20646793_20647016	0.49	RHOB	ras homolog family member B	69	0.98
chr20_57225612_57225784	0.49	STX16	syntaxin 16	630	0.69
chr8_143718654_143718805	0.49	AC145123.2		1220	0.37
chr9_95727192_95727343	0.49	FGD3	FYVE, RhoGEF and PH domain containing 3	1024	0.59
chr15_66993916_66994323	0.49	SMAD6	SMAD family member 6	447	0.87
chr19_1259356_1259507	0.48	CIRBP	cold inducible RNA binding protein	47	0.94
chr17_45331535_45331807	0.48	ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	408	0.78
chr2_98262920_98263071	0.48	COX5B	cytochrome c oxidase subunit Vb	492	0.75
chr9_140111540_140111691	0.47	RNF208	ring finger protein 208	4160	0.06
chr7_2773813_2774169	0.46	GNA12	guanine nucleotide binding protein (G protein) alpha 12	28783	0.18
chr9_93955690_93955949	0.46	AUH	AU RNA binding protein/enoyl-CoA hydratase	168358	0.04
chr9_124044825_124044976	0.46	RP11-477J21.6		108	0.95
chr8_95908069_95908288	0.45	NDUFAF6	NADH dehydrogenase (ubiquinone) complex I, assembly factor 6	113	0.89
chr9_79792561_79792712	0.45	VPS13A	vacuolar protein sorting 13 homolog A (S. cerevisiae)	186	0.62
chr1_15480223_15480374	0.45	TMEM51	transmembrane protein 51	13	0.98
chr7_73704371_73704680	0.44	CLIP2	CAP-GLY domain containing linker protein 2	720	0.67
chr11_126152650_126152801	0.44	TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	257	0.79
chr10_134198535_134198861	0.44	PWWP2B	PWWP domain containing 2B	11974	0.18
chr17_10601767_10602333	0.44	ADPRM	ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent	1139	0.3
chr17_32964862_32965155	0.44	TMEM132E	transmembrane protein 132E	57240	0.13
chr4_177116305_177116485	0.43	SPATA4	spermatogenesis associated 4	367	0.89
chr11_44087770_44087921	0.43	ACCS	1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)	27	0.97
chr7_120970262_120970413	0.43	WNT16	wingless-type MMTV integration site family, member 16	1280	0.58
chr17_75084743_75084894	0.43	ENSG00000234912	.	13	0.5
chr12_56522379_56522613	0.42	RP11-603J24.5		142	0.74
chr8_125732542_125732693	0.42	MTSS1	metastasis suppressor 1	7240	0.27
chr5_107006410_107006592	0.42	EFNA5	ephrin-A5	95	0.98
chr16_3508836_3509130	0.42	NAA60	N(alpha)-acetyltransferase 60, NatF catalytic subunit	853	0.49
chr3_47515038_47515202	0.42	SCAP	SREBF chaperone	1967	0.25
chr1_110329831_110329982	0.42	EPS8L3	EPS8-like 3	23257	0.13
chr14_103273974_103274344	0.41	ENSG00000238853	.	18231	0.16
chr5_16616400_16616653	0.41	RP11-260E18.1		491	0.55
chr21_28216356_28216601	0.41	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	382	0.9
chr1_7130417_7130568	0.41	RP11-334N17.1		56153	0.15
chr17_42015906_42016109	0.40	RP11-527L4.2	Uncharacterized protein	276	0.82
chr4_126237676_126237917	0.40	FAT4	FAT atypical cadherin 4	242	0.96
chrX_25031009_25031225	0.40	ARX	aristaless related homeobox	2948	0.35
chr16_88729091_88729284	0.40	MVD	mevalonate (diphospho) decarboxylase	331	0.56
chr6_144163884_144164159	0.40	LTV1	LTV1 homolog (S. cerevisiae)	460	0.86
chr3_151178863_151179038	0.40	IGSF10	immunoglobulin superfamily, member 10	2453	0.35
chr1_44874319_44874616	0.39	RNF220	ring finger protein 220	3303	0.23
chr11_130029367_130029526	0.39	ST14	suppression of tumorigenicity 14 (colon carcinoma)	11	0.99
chr8_22932902_22933095	0.39	RP11-875O11.3		997	0.41
chr12_31743313_31743464	0.39	DENND5B	DENN/MADD domain containing 5B	12	0.91
chr1_9460248_9460447	0.39	ENSG00000252956	.	37490	0.16
chr19_53497116_53497310	0.38	ERVV-1	endogenous retrovirus group V, member 1	19961	0.13
chr3_195622267_195622418	0.38	TNK2	tyrosine kinase, non-receptor, 2	90	0.96
chr5_175970644_175970798	0.38	CDHR2	cadherin-related family member 2	1209	0.33
chr6_41122373_41122524	0.38	TREML1	triggering receptor expressed on myeloid cells-like 1	373	0.81
chr1_6119056_6119207	0.38	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2	12957	0.17
chr1_169074204_169074389	0.38	ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide	639	0.54
chr3_170746420_170746613	0.37	SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	1977	0.38
chr8_28557924_28558130	0.37	EXTL3-AS1	EXTL3 antisense RNA 1	20	0.95
chr1_85358976_85359195	0.37	LPAR3	lysophosphatidic acid receptor 3	189	0.96
chr8_10489103_10489325	0.37	RP1L1	retinitis pigmentosa 1-like 1	23398	0.14
chr22_38350147_38350321	0.37	POLR2F	polymerase (RNA) II (DNA directed) polypeptide F	500	0.43
chr5_146257531_146257771	0.37	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	554	0.83
chr4_1772588_1772739	0.37	FGFR3	fibroblast growth factor receptor 3	22371	0.14
chr10_104628976_104629267	0.37	AS3MT	arsenic (+3 oxidation state) methyltransferase	152	0.89
chr13_20735494_20735765	0.37	GJA3	gap junction protein, alpha 3, 46kDa	441	0.83
chr8_145017915_145018082	0.36	PLEC	plectin	128	0.92
chr2_148601579_148601730	0.36	ACVR2A	activin A receptor, type IIA	432	0.86
chr11_72046071_72046222	0.36	RP11-45F15.1		16245	0.12
chr22_32341585_32341776	0.36	C22orf24	chromosome 22 open reading frame 24	344	0.78
chr17_70588695_70588877	0.36	ENSG00000200783	.	71505	0.12
chr1_36929556_36929707	0.36	MRPS15	mitochondrial ribosomal protein S15	407	0.8
chr1_155055483_155055634	0.36	EFNA3	ephrin-A3	4173	0.09
chr13_110959774_110959957	0.36	COL4A2	collagen, type IV, alpha 2	251	0.63
chr16_21513999_21514183	0.36	CTD-2547E10.2		884	0.53
chr1_154378255_154378406	0.36	IL6R	interleukin 6 receptor	239	0.79
chr19_46907976_46908238	0.35	CCDC8	coiled-coil domain containing 8	8734	0.13
chr1_119544370_119544543	0.35	TBX15	T-box 15	12277	0.25
chr22_47056423_47056825	0.35	GRAMD4	GRAM domain containing 4	2380	0.36
chr11_118308788_118309046	0.35	KMT2A	lysine (K)-specific methyltransferase 2A	1440	0.24
chr19_49244576_49244787	0.35	RASIP1	Ras interacting protein 1	703	0.46
chr3_149530679_149530830	0.35	RNF13	ring finger protein 13	82	0.97
chr14_93650600_93650813	0.34	MOAP1	modulator of apoptosis 1	562	0.33
chr12_112205981_112206148	0.34	ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)	1338	0.43
chr19_6551842_6551998	0.34	TNFSF9	tumor necrosis factor (ligand) superfamily, member 9	20910	0.1
chr22_43581545_43581696	0.34	TTLL12	tubulin tyrosine ligase-like family, member 12	1519	0.32
chr17_42296660_42296811	0.34	UBTF	upstream binding transcription factor, RNA polymerase I	131	0.89
chr19_44123224_44123375	0.34	ZNF428	zinc finger protein 428	452	0.63
chr7_51207916_51208067	0.34	COBL	cordon-bleu WH2 repeat protein	50649	0.18
chr1_16562852_16563214	0.34	RSG1	REM2 and RAB-like small GTPase 1	121	0.93
chr1_16175539_16175976	0.34	RP11-169K16.9		1115	0.36
chr5_483257_483408	0.33	ENSG00000225138	.	5972	0.13
chr9_139025848_139026088	0.33	C9orf69	chromosome 9 open reading frame 69	15237	0.18
chr13_28366681_28366832	0.33	GSX1	GS homeobox 1	24	0.98
chr8_38645258_38645409	0.33	TACC1	transforming, acidic coiled-coil containing protein 1	291	0.9
chr12_124953913_124954064	0.33	NCOR2	nuclear receptor corepressor 2	14327	0.29
chrX_49056071_49056222	0.33	SYP	synaptophysin	489	0.46
chr5_175094513_175094666	0.32	HRH2	histamine receptor H2	9556	0.21
chr1_3374183_3374334	0.32	ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16	3268	0.27
chr8_119072711_119072926	0.32	EXT1	exostosin glycosyltransferase 1	49835	0.19
chr18_54318745_54318896	0.32	TXNL1	thioredoxin-like 1	4	0.57
chr7_2177925_2178076	0.32	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	28764	0.21
chr15_30395989_30396219	0.32	ULK4P3	ULK4 pseudogene 3	6401	0.11
chr16_638518_638677	0.32	RAB40C	RAB40C, member RAS oncogene family	760	0.38
chr1_1141562_1141846	0.32	TNFRSF18	tumor necrosis factor receptor superfamily, member 18	247	0.81
chr17_79213388_79213539	0.32	C17orf89	chromosome 17 open reading frame 89	52	0.89
chr11_729103_729312	0.32	AP006621.9		2160	0.14
chr5_49736477_49736628	0.32	EMB	embigin	632	0.85
chr19_2785743_2785894	0.32	THOP1	thimet oligopeptidase 1	272	0.84
chr12_6756054_6756504	0.31	ACRBP	acrosin binding protein	280	0.79
chr17_65714562_65715117	0.31	NOL11	nucleolar protein 11	778	0.67
chr7_5633108_5633259	0.31	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	296	0.88
chr20_52560620_52560782	0.31	AC005220.3		4002	0.31
chr1_2230164_2230315	0.31	RP4-713A8.1		27893	0.1
chr22_19872739_19872890	0.31	GNB1L	guanine nucleotide binding protein (G protein), beta polypeptide 1-like	30352	0.11
chr4_7045919_7046070	0.31	TADA2B	transcriptional adaptor 2B	732	0.43
chr19_38886737_38887045	0.30	SPRED3	sprouty-related, EVH1 domain containing 3	6051	0.09
chr1_234792136_234792287	0.30	IRF2BP2	interferon regulatory factor 2 binding protein 2	46940	0.14
chr1_111888969_111889259	0.30	PIFO	primary cilia formation	128	0.94
chr16_49890952_49891163	0.30	ZNF423	zinc finger protein 423	773	0.72
chr22_45706548_45706752	0.30	FAM118A	family with sequence similarity 118, member A	645	0.72
chr17_36903950_36904124	0.30	PCGF2	polycomb group ring finger 2	400	0.61
chr8_146078459_146078610	0.30	COMMD5	COMM domain containing 5	82	0.73
chr3_170075767_170075918	0.30	SKIL	SKI-like oncogene	320	0.92
chr19_1295547_1295773	0.30	EFNA2	ephrin-A2	9507	0.09
chr18_52275487_52275768	0.30	DYNAP	dynactin associated protein	17237	0.28
chr15_62684221_62684372	0.30	RP11-299H22.5		121417	0.05
chr9_38392998_38393154	0.30	ALDH1B1	aldehyde dehydrogenase 1 family, member B1	415	0.88
chr3_38496003_38496273	0.30	ACVR2B-AS1	ACVR2B antisense RNA 1	173	0.88
chr17_64962073_64962262	0.30	CACNG4	calcium channel, voltage-dependent, gamma subunit 4	1141	0.49
chr5_114937889_114938040	0.29	AC010226.4		23	0.73
chr2_175351124_175351275	0.29	GPR155	G protein-coupled receptor 155	566	0.77
chr2_232526773_232526924	0.29	ENSG00000239202	.	15864	0.16
chr9_117267085_117267319	0.29	DFNB31	deafness, autosomal recessive 31	48	0.98
chr3_52001900_52002051	0.29	PCBP4	poly(rC) binding protein 4	225	0.82
chr17_7210325_7210491	0.29	EIF5A	eukaryotic translation initiation factor 5A	90	0.9
chr20_44718738_44718889	0.29	NCOA5	nuclear receptor coactivator 5	222	0.93
chrX_153717889_153718196	0.29	SLC10A3	solute carrier family 10, member 3	911	0.29
chr1_7740606_7740775	0.29	CAMTA1	calmodulin binding transcription activator 1	55778	0.13
chr21_34576303_34576454	0.29	IFNAR2	interferon (alpha, beta and omega) receptor 2	25828	0.13
chr16_87978728_87979195	0.29	BANP	BTG3 associated nuclear protein	5081	0.21
chr4_77870187_77870438	0.29	SEPT11	septin 11	544	0.82
chr1_63789848_63790019	0.29	RP4-792G4.2		179	0.91
chr22_35654391_35654690	0.29	HMGXB4	HMG box domain containing 4	1049	0.5
chr2_242866226_242866494	0.29	AC131097.3		9627	0.16
chr9_128003261_128003412	0.29	HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	273	0.73
chr16_30786411_30786721	0.29	RP11-2C24.6		3204	0.12
chr9_123476185_123476336	0.29	MEGF9	multiple EGF-like-domains 9	352	0.91
chr17_62142935_62143086	0.29	ICAM2	intercellular adhesion molecule 2	45016	0.1
chr5_71403276_71403541	0.29	MAP1B	microtubule-associated protein 1B	95	0.98
chr22_17589135_17589286	0.29	CECR6	cat eye syndrome chromosome region, candidate 6	12933	0.14
chr17_78427623_78427774	0.29	NPTX1	neuronal pentraxin I	22706	0.14
chr10_7449875_7450112	0.29	SFMBT2	Scm-like with four mbt domains 2	714	0.79
chr11_507502_507804	0.29	RNH1	ribonuclease/angiogenin inhibitor 1	353	0.74
chr1_51702849_51703000	0.29	RNF11	ring finger protein 11	981	0.47
chr19_58873786_58873995	0.29	CTD-2619J13.3		61	0.68
chr7_108210711_108210891	0.28	THAP5	THAP domain containing 5	607	0.53
chr1_1564883_1565149	0.28	MIB2	mindbomb E3 ubiquitin protein ligase 2	1147	0.27
chr5_79641880_79642031	0.28	ENSG00000206774	.	19696	0.15
chr16_89189658_89189820	0.28	CTD-2555A7.3		8052	0.16
chr15_50474903_50475054	0.28	ATP8B4	ATPase, class I, type 8B, member 4	36	0.91
chr6_5724424_5724681	0.28	RP1-256G22.2		29047	0.25
chr7_98972066_98972217	0.28	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	157	0.93
chr4_38670228_38671220	0.28	RP11-617D20.1		4220	0.19
chr6_7109059_7109210	0.28	RREB1	ras responsive element binding protein 1	870	0.67
chr1_1564281_1564601	0.28	MIB2	mindbomb E3 ubiquitin protein ligase 2	572	0.55
chr17_36904132_36904330	0.28	PCGF2	polycomb group ring finger 2	206	0.8
chr10_98414108_98414318	0.28	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	15155	0.19
chr8_95654443_95654651	0.28	ESRP1	epithelial splicing regulatory protein 1	707	0.64
chr19_39187007_39187237	0.28	CTB-186G2.4		2876	0.16
chr15_90605469_90605716	0.28	ZNF710	zinc finger protein 710	5654	0.16
chr16_19895576_19895754	0.28	GPRC5B	G protein-coupled receptor, family C, group 5, member B	521	0.79
chr5_55891548_55891699	0.28	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	10436	0.24
chr16_1360625_1361180	0.27	UBE2I	ubiquitin-conjugating enzyme E2I	970	0.34
chr17_79985077_79985228	0.27	STRA13	stimulated by retinoic acid 13	3169	0.09

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB7A_ZBTB7C

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1	0.6	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.1	0.4	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.4	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.4	GO:0032060	bleb assembly(GO:0032060)
0.1	0.4	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.3	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1	0.3	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.5	GO:0051788	response to misfolded protein(GO:0051788)
0.1	0.3	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.4	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.3	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1	0.3	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1	0.2	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.2	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.4	GO:0042117	monocyte activation(GO:0042117)
0.1	0.2	GO:0002328	pro-B cell differentiation(GO:0002328)
0.1	0.3	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.1	0.2	GO:1903332	regulation of protein folding(GO:1903332)
0.1	0.4	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.2	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1	0.4	GO:0045683	negative regulation of epidermis development(GO:0045683)
0.1	0.2	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1	0.4	GO:0051290	protein heterotetramerization(GO:0051290)
0.1	0.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.2	GO:0006167	AMP biosynthetic process(GO:0006167)
0.1	0.1	GO:0061054	dermatome development(GO:0061054)
0.1	0.2	GO:0097576	vacuole fusion(GO:0097576)
0.1	0.2	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.1	GO:0034113	heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.1	0.3	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1	0.5	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.1	0.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	0.2	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.1	0.2	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.1	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.1	0.5	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.1	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.3	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.4	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.4	GO:0018065	protein-cofactor linkage(GO:0018065)
0.0	0.0	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.2	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.4	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.2	GO:0021894	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.2	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.2	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.2	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.2	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.3	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.1	GO:0072070	loop of Henle development(GO:0072070)
0.0	0.1	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
0.0	0.2	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.3	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0003339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003339)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0021548	pons development(GO:0021548)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0048318	axial mesoderm development(GO:0048318)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.1	GO:0090192	regulation of glomerulus development(GO:0090192)
0.0	0.1	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0051834	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.2	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.2	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.1	GO:0045634	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.1	GO:0002911	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.2	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0	0.1	GO:0045217	cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.0	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0	0.4	GO:0030901	midbrain development(GO:0030901)
0.0	0.1	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.3	GO:0009268	response to pH(GO:0009268)
0.0	0.0	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.0	GO:0061526	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0	0.4	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	1.3	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.3	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.0	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.1	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0097354	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.1	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.2	GO:1904377	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.1	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.0	GO:0014805	smooth muscle adaptation(GO:0014805)
0.0	0.2	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.5	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.2	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.1	GO:0060713	embryonic placenta morphogenesis(GO:0060669) labyrinthine layer morphogenesis(GO:0060713)
0.0	0.1	GO:0043266	regulation of potassium ion transport(GO:0043266)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0006152	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.3	GO:0001754	eye photoreceptor cell differentiation(GO:0001754)
0.0	0.1	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.3	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.0	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0046174	polyol catabolic process(GO:0046174)
0.0	0.1	GO:0035121	obsolete tail morphogenesis(GO:0035121)
0.0	0.8	GO:0016358	dendrite development(GO:0016358)
0.0	0.1	GO:0010626	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) regulation of glial cell proliferation(GO:0060251) negative regulation of glial cell proliferation(GO:0060253)
0.0	0.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.2	GO:0000050	urea cycle(GO:0000050)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.2	GO:0006386	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.2	GO:0097191	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.2	GO:0001706	endoderm formation(GO:0001706)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.0	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.2	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.2	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.2	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.0	0.1	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.1	GO:0031620	regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.3	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.3	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.2	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.0	0.0	GO:0021794	thalamus development(GO:0021794)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0001562	response to protozoan(GO:0001562)
0.0	0.1	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.0	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.1	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.0	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.1	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.2	GO:0060135	maternal process involved in female pregnancy(GO:0060135)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.1	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.3	GO:0016525	negative regulation of angiogenesis(GO:0016525) negative regulation of vasculature development(GO:1901343) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.2	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.2	GO:0010043	response to zinc ion(GO:0010043)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0045744	negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0	0.4	GO:1901799	negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0	0.0	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.0	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.2	GO:0001990	regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.0	0.0	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0045824	negative regulation of innate immune response(GO:0045824)
0.0	0.0	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:1902099	regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0	0.0	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.2	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.1	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.0	GO:0032700	negative regulation of interleukin-17 production(GO:0032700)
0.0	0.1	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.4	GO:0019722	calcium-mediated signaling(GO:0019722)
0.0	0.2	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.0	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.3	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.0	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.0	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0043501	skeletal muscle adaptation(GO:0043501)
0.0	0.1	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.0	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.0	GO:0042819	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:0035195	gene silencing by miRNA(GO:0035195)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.4	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	0.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.1	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1	0.4	GO:0001739	sex chromatin(GO:0001739)
0.1	0.4	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.1	0.5	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.1	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	0.3	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.6	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.2	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.4	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	1.1	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.3	GO:0031201	SNARE complex(GO:0031201)
0.0	0.5	GO:0043204	perikaryon(GO:0043204)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.4	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.0	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.5	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.7	GO:0019897	extrinsic component of plasma membrane(GO:0019897)
0.0	0.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.7	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.0	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.0	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.0	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	1.3	GO:0005912	adherens junction(GO:0005912)
0.0	0.1	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.0	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0016972	thiol oxidase activity(GO:0016972)
0.2	0.6	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.1	0.4	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.3	GO:0016362	activin receptor activity, type II(GO:0016362)
0.1	0.3	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.1	0.4	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.5	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.1	0.3	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	0.3	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	0.8	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.2	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.1	0.2	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.3	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.3	GO:0017070	U6 snRNA binding(GO:0017070)
0.1	0.5	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.3	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.6	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.5	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.1	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.0	GO:0015421	oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0	0.4	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.4	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0051380	norepinephrine binding(GO:0051380)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.4	GO:0005035	death receptor activity(GO:0005035)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.6	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.3	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.3	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.7	GO:0019003	GDP binding(GO:0019003)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.4	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.2	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.8	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.3	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.5	GO:0016675	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.3	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.2	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.4	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.4	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.3	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.2	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.3	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.3	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0001537	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.2	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	1.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.8	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0	0.1	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.3	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.5	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.0	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.0	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.0	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.3	GO:1990837	sequence-specific double-stranded DNA binding(GO:1990837)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.3	GO:0004180	carboxypeptidase activity(GO:0004180)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	1.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.3	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.6	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.0	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.7	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.6	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.4	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.7	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.4	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.3	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.2	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.4	PID BMP PATHWAY	BMP receptor signaling
0.0	0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.6	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.6	PID ATR PATHWAY	ATR signaling pathway
0.0	0.3	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.6	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.3	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.3	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	PID HNF3A PATHWAY	FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.7	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.5	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.5	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.4	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.4	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.5	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.5	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.0	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.2	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.2	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.3	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.0	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage