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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ZBTB7A_ZBTB7C

Z-value: 2.09

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Transcription factors associated with ZBTB7A_ZBTB7C

Gene Symbol Gene ID Gene Info
ZBTB7A
ENSG00000178951.4 zinc finger and BTB domain containing 7A
ZBTB7C
ENSG00000184828.5 zinc finger and BTB domain containing 7C

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr19_4064373_4064526ZBTB7A12810.2770020.924.3e-04Click!
chr19_4082277_4082468ZBTB7A154290.1064010.925.4e-04Click!
chr19_4066977_4067128ZBTB7A1090.9405580.854.0e-03Click!
chr19_4078452_4078630ZBTB7A115980.1108010.827.0e-03Click!
chr19_4066237_4066388ZBTB7A5820.6141010.801.0e-02Click!
chr18_45936153_45936382ZBTB7C4740.8387290.966.1e-05Click!
chr18_45534337_45534541ZBTB7C330550.2084610.932.8e-04Click!
chr18_45688335_45688486ZBTB7C32920.2868910.916.7e-04Click!
chr18_45663037_45663235ZBTB7C5960.8068580.891.2e-03Click!
chr18_45935563_45935714ZBTB7C250.9814510.872.2e-03Click!

Activity of the ZBTB7A_ZBTB7C motif across conditions

Conditions sorted by the z-value of the ZBTB7A_ZBTB7C motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_140772630_140772870 0.94 TMEM178B
 transmembrane protein 178B
 1282
 0.5
chr15_33487170_33487350 0.93 FMN1
 formin 1
 363
 0.92
chr16_57199787_57199938 0.87 FAM192A
 family with sequence similarity 192, member A
 7838
 0.15
chr7_37960937_37961095 0.85 EPDR1
 ependymin related 1
 94
 0.97
chr8_145731715_145731866 0.85 ENSG00000255182
 .
 963
 0.24
chr8_144976835_144977223 0.82 PLEC
 plectin
 24150
 0.09
chr22_50907441_50907726 0.80 SBF1
 SET binding factor 1
 5788
 0.09
chr10_122216941_122217092 0.79 PPAPDC1A
 phosphatidic acid phosphatase type 2 domain containing 1A
 257
 0.94
chr3_14482734_14482908 0.79 SLC6A6
 solute carrier family 6 (neurotransmitter transporter), member 6
 8643
 0.24
chr1_180123457_180123608 0.76 QSOX1
 quiescin Q6 sulfhydryl oxidase 1
 437
 0.87
chr22_19435389_19435540 0.73 AC000068.5
48
 0.6
chrX_53118423_53118574 0.69 TSPYL2
 TSPY-like 2
 6935
 0.19
chr13_41239473_41239624 0.67 FOXO1
 forkhead box O1
 1186
 0.56
chr7_66147471_66147622 0.63 RP4-756H11.3
27973
 0.16
chr6_87865528_87865679 0.62 ZNF292
 zinc finger protein 292
 264
 0.76
chr4_56212156_56212324 0.59 SRD5A3
 steroid 5 alpha-reductase 3
 36
 0.98
chr2_128990579_128990730 0.58 UGGT1
 UDP-glucose glycoprotein glucosyltransferase 1
 53294
 0.14
chr6_28602727_28602878 0.58 ENSG00000272278
 .
 13240
 0.2
chr1_10651223_10651374 0.57 ENSG00000243267
 .
 25595
 0.16
chrX_55516093_55516244 0.57 USP51
 ubiquitin specific peptidase 51
 533
 0.8
chr10_71390210_71390493 0.56 C10orf35
 chromosome 10 open reading frame 35
 51
 0.98
chr17_77966270_77966521 0.55 CTD-2529O21.1
245
 0.85
chr5_141348457_141348608 0.54 RNF14
 ring finger protein 14
 72
 0.96
chr1_2210385_2210536 0.53 RP4-713A8.1
47672
 0.08
chr17_78261654_78261965 0.53 RNF213
 ring finger protein 213
 27140
 0.13
chr10_52834025_52834306 0.53 PRKG1
 protein kinase, cGMP-dependent, type I
 231
 0.94
chr8_495904_496055 0.52 TDRP
 testis development related protein
 198
 0.96
chr8_27471547_27471716 0.51 CLU
 clusterin
 129
 0.96
chr22_17588430_17588590 0.51 CECR6
 cat eye syndrome chromosome region, candidate 6
 13633
 0.14
chr1_205744099_205744250 0.51 RAB7L1
 RAB7, member RAS oncogene family-like 1
 187
 0.93
chrX_68384913_68385097 0.51 PJA1
 praja ring finger 1, E3 ubiquitin protein ligase
 275
 0.96
chr2_20646793_20647016 0.49 RHOB
 ras homolog family member B
 69
 0.98
chr20_57225612_57225784 0.49 STX16
 syntaxin 16
 630
 0.69
chr8_143718654_143718805 0.49 AC145123.2
1220
 0.37
chr9_95727192_95727343 0.49 FGD3
 FYVE, RhoGEF and PH domain containing 3
 1024
 0.59
chr15_66993916_66994323 0.49 SMAD6
 SMAD family member 6
 447
 0.87
chr19_1259356_1259507 0.48 CIRBP
 cold inducible RNA binding protein
 47
 0.94
chr17_45331535_45331807 0.48 ITGB3
 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
 408
 0.78
chr2_98262920_98263071 0.48 COX5B
 cytochrome c oxidase subunit Vb
 492
 0.75
chr9_140111540_140111691 0.47 RNF208
 ring finger protein 208
 4160
 0.06
chr7_2773813_2774169 0.46 GNA12
 guanine nucleotide binding protein (G protein) alpha 12
 28783
 0.18
chr9_93955690_93955949 0.46 AUH
 AU RNA binding protein/enoyl-CoA hydratase
 168358
 0.04
chr9_124044825_124044976 0.46 RP11-477J21.6
108
 0.95
chr8_95908069_95908288 0.45 NDUFAF6
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
 113
 0.89
chr9_79792561_79792712 0.45 VPS13A
 vacuolar protein sorting 13 homolog A (S. cerevisiae)
 186
 0.62
chr1_15480223_15480374 0.45 TMEM51
 transmembrane protein 51
 13
 0.98
chr7_73704371_73704680 0.44 CLIP2
 CAP-GLY domain containing linker protein 2
 720
 0.67
chr11_126152650_126152801 0.44 TIRAP
 toll-interleukin 1 receptor (TIR) domain containing adaptor protein
 257
 0.79
chr10_134198535_134198861 0.44 PWWP2B
 PWWP domain containing 2B
 11974
 0.18
chr17_10601767_10602333 0.44 ADPRM
 ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
 1139
 0.3
chr17_32964862_32965155 0.44 TMEM132E
 transmembrane protein 132E
 57240
 0.13
chr4_177116305_177116485 0.43 SPATA4
 spermatogenesis associated 4
 367
 0.89
chr11_44087770_44087921 0.43 ACCS
 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
 27
 0.97
chr7_120970262_120970413 0.43 WNT16
 wingless-type MMTV integration site family, member 16
 1280
 0.58
chr17_75084743_75084894 0.43 ENSG00000234912
 .
 13
 0.5
chr12_56522379_56522613 0.42 RP11-603J24.5
142
 0.74
chr8_125732542_125732693 0.42 MTSS1
 metastasis suppressor 1
 7240
 0.27
chr5_107006410_107006592 0.42 EFNA5
 ephrin-A5
 95
 0.98
chr16_3508836_3509130 0.42 NAA60
 N(alpha)-acetyltransferase 60, NatF catalytic subunit
 853
 0.49
chr3_47515038_47515202 0.42 SCAP
 SREBF chaperone
 1967
 0.25
chr1_110329831_110329982 0.42 EPS8L3
 EPS8-like 3
 23257
 0.13
chr14_103273974_103274344 0.41 ENSG00000238853
 .
 18231
 0.16
chr5_16616400_16616653 0.41 RP11-260E18.1
491
 0.55
chr21_28216356_28216601 0.41 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
 382
 0.9
chr1_7130417_7130568 0.41 RP11-334N17.1
56153
 0.15
chr17_42015906_42016109 0.40 RP11-527L4.2
 Uncharacterized protein
 276
 0.82
chr4_126237676_126237917 0.40 FAT4
 FAT atypical cadherin 4
 242
 0.96
chrX_25031009_25031225 0.40 ARX
 aristaless related homeobox
 2948
 0.35
chr16_88729091_88729284 0.40 MVD
 mevalonate (diphospho) decarboxylase
 331
 0.56
chr6_144163884_144164159 0.40 LTV1
 LTV1 homolog (S. cerevisiae)
 460
 0.86
chr3_151178863_151179038 0.40 IGSF10
 immunoglobulin superfamily, member 10
 2453
 0.35
chr1_44874319_44874616 0.39 RNF220
 ring finger protein 220
 3303
 0.23
chr11_130029367_130029526 0.39 ST14
 suppression of tumorigenicity 14 (colon carcinoma)
 11
 0.99
chr8_22932902_22933095 0.39 RP11-875O11.3
997
 0.41
chr12_31743313_31743464 0.39 DENND5B
 DENN/MADD domain containing 5B
 12
 0.91
chr1_9460248_9460447 0.39 ENSG00000252956
 .
 37490
 0.16
chr19_53497116_53497310 0.38 ERVV-1
 endogenous retrovirus group V, member 1
 19961
 0.13
chr3_195622267_195622418 0.38 TNK2
 tyrosine kinase, non-receptor, 2
 90
 0.96
chr5_175970644_175970798 0.38 CDHR2
 cadherin-related family member 2
 1209
 0.33
chr6_41122373_41122524 0.38 TREML1
 triggering receptor expressed on myeloid cells-like 1
 373
 0.81
chr1_6119056_6119207 0.38 KCNAB2
 potassium voltage-gated channel, shaker-related subfamily, beta member 2
 12957
 0.17
chr1_169074204_169074389 0.38 ATP1B1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
 639
 0.54
chr3_170746420_170746613 0.37 SLC2A2
 solute carrier family 2 (facilitated glucose transporter), member 2
 1977
 0.38
chr8_28557924_28558130 0.37 EXTL3-AS1
 EXTL3 antisense RNA 1
 20
 0.95
chr1_85358976_85359195 0.37 LPAR3
 lysophosphatidic acid receptor 3
 189
 0.96
chr8_10489103_10489325 0.37 RP1L1
 retinitis pigmentosa 1-like 1
 23398
 0.14
chr22_38350147_38350321 0.37 POLR2F
 polymerase (RNA) II (DNA directed) polypeptide F
 500
 0.43
chr5_146257531_146257771 0.37 PPP2R2B
 protein phosphatase 2, regulatory subunit B, beta
 554
 0.83
chr4_1772588_1772739 0.37 FGFR3
 fibroblast growth factor receptor 3
 22371
 0.14
chr10_104628976_104629267 0.37 AS3MT
 arsenic (+3 oxidation state) methyltransferase
 152
 0.89
chr13_20735494_20735765 0.37 GJA3
 gap junction protein, alpha 3, 46kDa
 441
 0.83
chr8_145017915_145018082 0.36 PLEC
 plectin
 128
 0.92
chr2_148601579_148601730 0.36 ACVR2A
 activin A receptor, type IIA
 432
 0.86
chr11_72046071_72046222 0.36 RP11-45F15.1
16245
 0.12
chr22_32341585_32341776 0.36 C22orf24
 chromosome 22 open reading frame 24
 344
 0.78
chr17_70588695_70588877 0.36 ENSG00000200783
 .
 71505
 0.12
chr1_36929556_36929707 0.36 MRPS15
 mitochondrial ribosomal protein S15
 407
 0.8
chr1_155055483_155055634 0.36 EFNA3
 ephrin-A3
 4173
 0.09
chr13_110959774_110959957 0.36 COL4A2
 collagen, type IV, alpha 2
 251
 0.63
chr16_21513999_21514183 0.36 CTD-2547E10.2
884
 0.53
chr1_154378255_154378406 0.36 IL6R
 interleukin 6 receptor
 239
 0.79
chr19_46907976_46908238 0.35 CCDC8
 coiled-coil domain containing 8
 8734
 0.13
chr1_119544370_119544543 0.35 TBX15
 T-box 15
 12277
 0.25
chr22_47056423_47056825 0.35 GRAMD4
 GRAM domain containing 4
 2380
 0.36
chr11_118308788_118309046 0.35 KMT2A
 lysine (K)-specific methyltransferase 2A
 1440
 0.24
chr19_49244576_49244787 0.35 RASIP1
 Ras interacting protein 1
 703
 0.46
chr3_149530679_149530830 0.35 RNF13
 ring finger protein 13
 82
 0.97
chr14_93650600_93650813 0.34 MOAP1
 modulator of apoptosis 1
 562
 0.33
chr12_112205981_112206148 0.34 ALDH2
 aldehyde dehydrogenase 2 family (mitochondrial)
 1338
 0.43
chr19_6551842_6551998 0.34 TNFSF9
 tumor necrosis factor (ligand) superfamily, member 9
 20910
 0.1
chr22_43581545_43581696 0.34 TTLL12
 tubulin tyrosine ligase-like family, member 12
 1519
 0.32
chr17_42296660_42296811 0.34 UBTF
 upstream binding transcription factor, RNA polymerase I
 131
 0.89
chr19_44123224_44123375 0.34 ZNF428
 zinc finger protein 428
 452
 0.63
chr7_51207916_51208067 0.34 COBL
 cordon-bleu WH2 repeat protein
 50649
 0.18
chr1_16562852_16563214 0.34 RSG1
 REM2 and RAB-like small GTPase 1
 121
 0.93
chr1_16175539_16175976 0.34 RP11-169K16.9
1115
 0.36
chr5_483257_483408 0.33 ENSG00000225138
 .
 5972
 0.13
chr9_139025848_139026088 0.33 C9orf69
 chromosome 9 open reading frame 69
 15237
 0.18
chr13_28366681_28366832 0.33 GSX1
 GS homeobox 1
 24
 0.98
chr8_38645258_38645409 0.33 TACC1
 transforming, acidic coiled-coil containing protein 1
 291
 0.9
chr12_124953913_124954064 0.33 NCOR2
 nuclear receptor corepressor 2
 14327
 0.29
chrX_49056071_49056222 0.33 SYP
 synaptophysin
 489
 0.46
chr5_175094513_175094666 0.32 HRH2
 histamine receptor H2
 9556
 0.21
chr1_3374183_3374334 0.32 ARHGEF16
 Rho guanine nucleotide exchange factor (GEF) 16
 3268
 0.27
chr8_119072711_119072926 0.32 EXT1
 exostosin glycosyltransferase 1
 49835
 0.19
chr18_54318745_54318896 0.32 TXNL1
 thioredoxin-like 1
 4
 0.57
chr7_2177925_2178076 0.32 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 28764
 0.21
chr15_30395989_30396219 0.32 ULK4P3
 ULK4 pseudogene 3
 6401
 0.11
chr16_638518_638677 0.32 RAB40C
 RAB40C, member RAS oncogene family
 760
 0.38
chr1_1141562_1141846 0.32 TNFRSF18
 tumor necrosis factor receptor superfamily, member 18
 247
 0.81
chr17_79213388_79213539 0.32 C17orf89
 chromosome 17 open reading frame 89
 52
 0.89
chr11_729103_729312 0.32 AP006621.9
2160
 0.14
chr5_49736477_49736628 0.32 EMB
 embigin
 632
 0.85
chr19_2785743_2785894 0.32 THOP1
 thimet oligopeptidase 1
 272
 0.84
chr12_6756054_6756504 0.31 ACRBP
 acrosin binding protein
 280
 0.79
chr17_65714562_65715117 0.31 NOL11
 nucleolar protein 11
 778
 0.67
chr7_5633108_5633259 0.31 FSCN1
 fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
 296
 0.88
chr20_52560620_52560782 0.31 AC005220.3
4002
 0.31
chr1_2230164_2230315 0.31 RP4-713A8.1
27893
 0.1
chr22_19872739_19872890 0.31 GNB1L
 guanine nucleotide binding protein (G protein), beta polypeptide 1-like
 30352
 0.11
chr4_7045919_7046070 0.31 TADA2B
 transcriptional adaptor 2B
 732
 0.43
chr19_38886737_38887045 0.30 SPRED3
 sprouty-related, EVH1 domain containing 3
 6051
 0.09
chr1_234792136_234792287 0.30 IRF2BP2
 interferon regulatory factor 2 binding protein 2
 46940
 0.14
chr1_111888969_111889259 0.30 PIFO
 primary cilia formation
 128
 0.94
chr16_49890952_49891163 0.30 ZNF423
 zinc finger protein 423
 773
 0.72
chr22_45706548_45706752 0.30 FAM118A
 family with sequence similarity 118, member A
 645
 0.72
chr17_36903950_36904124 0.30 PCGF2
 polycomb group ring finger 2
 400
 0.61
chr8_146078459_146078610 0.30 COMMD5
 COMM domain containing 5
 82
 0.73
chr3_170075767_170075918 0.30 SKIL
 SKI-like oncogene
 320
 0.92
chr19_1295547_1295773 0.30 EFNA2
 ephrin-A2
 9507
 0.09
chr18_52275487_52275768 0.30 DYNAP
 dynactin associated protein
 17237
 0.28
chr15_62684221_62684372 0.30 RP11-299H22.5
121417
 0.05
chr9_38392998_38393154 0.30 ALDH1B1
 aldehyde dehydrogenase 1 family, member B1
 415
 0.88
chr3_38496003_38496273 0.30 ACVR2B-AS1
 ACVR2B antisense RNA 1
 173
 0.88
chr17_64962073_64962262 0.30 CACNG4
 calcium channel, voltage-dependent, gamma subunit 4
 1141
 0.49
chr5_114937889_114938040 0.29 AC010226.4
23
 0.73
chr2_175351124_175351275 0.29 GPR155
 G protein-coupled receptor 155
 566
 0.77
chr2_232526773_232526924 0.29 ENSG00000239202
 .
 15864
 0.16
chr9_117267085_117267319 0.29 DFNB31
 deafness, autosomal recessive 31
 48
 0.98
chr3_52001900_52002051 0.29 PCBP4
 poly(rC) binding protein 4
 225
 0.82
chr17_7210325_7210491 0.29 EIF5A
 eukaryotic translation initiation factor 5A
 90
 0.9
chr20_44718738_44718889 0.29 NCOA5
 nuclear receptor coactivator 5
 222
 0.93
chrX_153717889_153718196 0.29 SLC10A3
 solute carrier family 10, member 3
 911
 0.29
chr1_7740606_7740775 0.29 CAMTA1
 calmodulin binding transcription activator 1
 55778
 0.13
chr21_34576303_34576454 0.29 IFNAR2
 interferon (alpha, beta and omega) receptor 2
 25828
 0.13
chr16_87978728_87979195 0.29 BANP
 BTG3 associated nuclear protein
 5081
 0.21
chr4_77870187_77870438 0.29 SEPT11
 septin 11
 544
 0.82
chr1_63789848_63790019 0.29 RP4-792G4.2
179
 0.91
chr22_35654391_35654690 0.29 HMGXB4
 HMG box domain containing 4
 1049
 0.5
chr2_242866226_242866494 0.29 AC131097.3
9627
 0.16
chr9_128003261_128003412 0.29 HSPA5
 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
 273
 0.73
chr16_30786411_30786721 0.29 RP11-2C24.6
3204
 0.12
chr9_123476185_123476336 0.29 MEGF9
 multiple EGF-like-domains 9
 352
 0.91
chr17_62142935_62143086 0.29 ICAM2
 intercellular adhesion molecule 2
 45016
 0.1
chr5_71403276_71403541 0.29 MAP1B
 microtubule-associated protein 1B
 95
 0.98
chr22_17589135_17589286 0.29 CECR6
 cat eye syndrome chromosome region, candidate 6
 12933
 0.14
chr17_78427623_78427774 0.29 NPTX1
 neuronal pentraxin I
 22706
 0.14
chr10_7449875_7450112 0.29 SFMBT2
 Scm-like with four mbt domains 2
 714
 0.79
chr11_507502_507804 0.29 RNH1
 ribonuclease/angiogenin inhibitor 1
 353
 0.74
chr1_51702849_51703000 0.29 RNF11
 ring finger protein 11
 981
 0.47
chr19_58873786_58873995 0.29 CTD-2619J13.3
61
 0.68
chr7_108210711_108210891 0.28 THAP5
 THAP domain containing 5
 607
 0.53
chr1_1564883_1565149 0.28 MIB2
 mindbomb E3 ubiquitin protein ligase 2
 1147
 0.27
chr5_79641880_79642031 0.28 ENSG00000206774
 .
 19696
 0.15
chr16_89189658_89189820 0.28 CTD-2555A7.3
8052
 0.16
chr15_50474903_50475054 0.28 ATP8B4
 ATPase, class I, type 8B, member 4
 36
 0.91
chr6_5724424_5724681 0.28 RP1-256G22.2
29047
 0.25
chr7_98972066_98972217 0.28 ARPC1B
 actin related protein 2/3 complex, subunit 1B, 41kDa
 157
 0.93
chr4_38670228_38671220 0.28 RP11-617D20.1
4220
 0.19
chr6_7109059_7109210 0.28 RREB1
 ras responsive element binding protein 1
 870
 0.67
chr1_1564281_1564601 0.28 MIB2
 mindbomb E3 ubiquitin protein ligase 2
 572
 0.55
chr17_36904132_36904330 0.28 PCGF2
 polycomb group ring finger 2
 206
 0.8
chr10_98414108_98414318 0.28 PIK3AP1
 phosphoinositide-3-kinase adaptor protein 1
 15155
 0.19
chr8_95654443_95654651 0.28 ESRP1
 epithelial splicing regulatory protein 1
 707
 0.64
chr19_39187007_39187237 0.28 CTB-186G2.4
2876
 0.16
chr15_90605469_90605716 0.28 ZNF710
 zinc finger protein 710
 5654
 0.16
chr16_19895576_19895754 0.28 GPRC5B
 G protein-coupled receptor, family C, group 5, member B
 521
 0.79
chr5_55891548_55891699 0.28 AC022431.2
 Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
 10436
 0.24
chr16_1360625_1361180 0.27 UBE2I
 ubiquitin-conjugating enzyme E2I
 970
 0.34
chr17_79985077_79985228 0.27 STRA13
 stimulated by retinoic acid 13
 3169
 0.09

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB7A_ZBTB7C

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1 0.6 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.1 0.4 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.4 GO:0032060 bleb assembly(GO:0032060)
0.1 0.4 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.3 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.5 GO:0051788 response to misfolded protein(GO:0051788)
0.1 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 0.2 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.4 GO:0042117 monocyte activation(GO:0042117)
0.1 0.2 GO:0002328 pro-B cell differentiation(GO:0002328)
0.1 0.3 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 0.2 GO:1903332 regulation of protein folding(GO:1903332)
0.1 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.4 GO:0045683 negative regulation of epidermis development(GO:0045683)
0.1 0.2 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1 0.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.2 GO:0006167 AMP biosynthetic process(GO:0006167)
0.1 0.1 GO:0061054 dermatome development(GO:0061054)
0.1 0.2 GO:0097576 vacuole fusion(GO:0097576)
0.1 0.2 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.1 GO:0034113 heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.1 0.3 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1 0.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.2 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.1 0.2 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.1 GO:0045714 regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.1 0.5 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.3 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.4 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.4 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.0 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.4 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.2 GO:0021894 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.2 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.2 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:0036296 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.3 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003339)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0021548 pons development(GO:0021548)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.0 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0090192 regulation of glomerulus development(GO:0090192)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:2000192 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.2 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.2 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0002911 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0052033 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0045217 cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.4 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.3 GO:0009268 response to pH(GO:0009268)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0033145 positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0 0.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 1.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.0 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:1904377 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.1 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.0 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.2 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.5 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0060713 embryonic placenta morphogenesis(GO:0060669) labyrinthine layer morphogenesis(GO:0060713)
0.0 0.1 GO:0043266 regulation of potassium ion transport(GO:0043266)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.3 GO:0001754 eye photoreceptor cell differentiation(GO:0001754)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0046174 polyol catabolic process(GO:0046174)
0.0 0.1 GO:0035121 obsolete tail morphogenesis(GO:0035121)
0.0 0.8 GO:0016358 dendrite development(GO:0016358)
0.0 0.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) regulation of glial cell proliferation(GO:0060251) negative regulation of glial cell proliferation(GO:0060253)
0.0 0.2 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.2 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.2 GO:0097191 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.0 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.0 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.2 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.2 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.0 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0031620 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.3 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.3 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.2 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.0 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0001562 response to protozoan(GO:0001562)
0.0 0.1 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.0 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.0 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.0 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.1 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.1 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.3 GO:0016525 negative regulation of angiogenesis(GO:0016525) negative regulation of vasculature development(GO:1901343) negative regulation of blood vessel morphogenesis(GO:2000181)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.2 GO:0010043 response to zinc ion(GO:0010043)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.4 GO:1901799 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799)
0.0 0.0 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.2 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.0 0.0 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.0 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:1902099 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.1 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.0 GO:0032700 negative regulation of interleukin-17 production(GO:0032700)
0.0 0.1 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.0 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.0 GO:0003197 endocardial cushion development(GO:0003197)
0.0 0.0 GO:0003283 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.0 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.0 0.1 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.0 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0035195 gene silencing by miRNA(GO:0035195)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.1 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.1 0.4 GO:0001739 sex chromatin(GO:0001739)
0.1 0.4 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.5 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.3 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.0 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.7 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 0.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.7 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 1.3 GO:0005912 adherens junction(GO:0005912)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.0 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.0 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016972 thiol oxidase activity(GO:0016972)
0.2 0.6 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.1 0.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 0.3 GO:0016362 activin receptor activity, type II(GO:0016362)
0.1 0.3 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.1 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.5 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.1 0.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.8 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.3 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.5 GO:0030371 translation repressor activity(GO:0030371)
0.1 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.5 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.0 GO:0015421 oligopeptide-transporting ATPase activity(GO:0015421) peptide-transporting ATPase activity(GO:0015440)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0005035 death receptor activity(GO:0005035)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.2 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.5 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 1.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.8 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.0 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.0 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:1990837 sequence-specific double-stranded DNA binding(GO:1990837)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0004180 carboxypeptidase activity(GO:0004180)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 1.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.6 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 1.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.6 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.1 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.9 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.1 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage