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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ZFHX3

Z-value: 1.53

Motif logo

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Transcription factors associated with ZFHX3

Gene Symbol Gene ID Gene Info
ZFHX3
ENSG00000140836.10 zinc finger homeobox 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr16_73128008_73128159ZFHX3344860.179269-0.972.0e-05Click!
chr16_73080724_73080969ZFHX314280.472491-0.872.5e-03Click!
chr16_73080996_73081147ZFHX312030.533635-0.862.6e-03Click!
chr16_73102131_73102454ZFHX386950.241874-0.845.0e-03Click!
chr16_73101800_73101951ZFHX382780.243204-0.836.2e-03Click!

Activity of the ZFHX3 motif across conditions

Conditions sorted by the z-value of the ZFHX3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_14599434_14599610 0.89 FAM107B
 family with sequence similarity 107, member B
 1343
 0.53
chr6_130537041_130537253 0.82 SAMD3
 sterile alpha motif domain containing 3
 68
 0.98
chr6_20336837_20336988 0.78 E2F3
 E2F transcription factor 3
 65486
 0.1
chr1_198663697_198663875 0.72 RP11-553K8.5
27596
 0.22
chr3_186743797_186744281 0.69 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 768
 0.72
chr1_160576647_160576798 0.66 CD84
 CD84 molecule
 27416
 0.12
chr15_22452071_22452222 0.65 IGHV1OR15-1
 immunoglobulin heavy variable 1/OR15-1 (non-functional)
 3327
 0.16
chr12_104860037_104860188 0.64 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 9333
 0.28
chr12_94599007_94599198 0.63 RP11-74K11.2
19282
 0.19
chr3_59997046_59997753 0.63 NPCDR1
 nasopharyngeal carcinoma, down-regulated 1
 39816
 0.23
chr16_50720309_50720716 0.63 SNX20
 sorting nexin 20
 5248
 0.13
chr7_37055765_37056093 0.62 ELMO1-AS1
 ELMO1 antisense RNA 1
 18528
 0.2
chr6_111008371_111008642 0.61 ENSG00000200522
 .
 35045
 0.17
chr13_99930486_99930694 0.61 GPR18
 G protein-coupled receptor 18
 16592
 0.18
chr15_62148914_62149135 0.60 RP11-16B9.1
22073
 0.23
chr7_1085249_1085400 0.58 GPR146
 G protein-coupled receptor 146
 1112
 0.32
chr8_82015786_82015967 0.58 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 8427
 0.3
chr1_109188916_109189073 0.58 HENMT1
 HEN1 methyltransferase homolog 1 (Arabidopsis)
 14683
 0.19
chr13_41543655_41543806 0.57 ELF1
 E74-like factor 1 (ets domain transcription factor)
 12688
 0.19
chr2_213980870_213981021 0.57 IKZF2
 IKAROS family zinc finger 2 (Helios)
 32408
 0.23
chrX_146996931_146997212 0.57 FMR1
 fragile X mental retardation 1
 3373
 0.19
chr1_198639351_198639502 0.57 RP11-553K8.5
3236
 0.32
chr9_37302020_37302197 0.57 ENSG00000216070
 .
 6007
 0.22
chr4_78075898_78076211 0.56 CCNG2
 cyclin G2
 2250
 0.33
chr17_74250036_74250213 0.56 UBALD2
 UBA-like domain containing 2
 11159
 0.13
chrX_70754467_70754618 0.55 OGT
 O-linked N-acetylglucosamine (GlcNAc) transferase
 391
 0.86
chr12_106856803_106856954 0.55 POLR3B
 polymerase (RNA) III (DNA directed) polypeptide B
 81128
 0.09
chrX_65207483_65207634 0.55 RP6-159A1.3
12035
 0.22
chr7_134837346_134837497 0.53 AC083862.1
 Uncharacterized protein
 4505
 0.16
chr21_36397619_36398181 0.52 RUNX1
 runt-related transcription factor 1
 23562
 0.28
chrX_24516682_24516850 0.52 ENSG00000265506
 .
 18691
 0.19
chr11_48041048_48041486 0.52 AC103828.1
3860
 0.26
chr8_19553650_19553834 0.52 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
 13470
 0.29
chr12_62665356_62665507 0.52 USP15
 ubiquitin specific peptidase 15
 6978
 0.22
chr1_114322751_114323179 0.52 PHTF1
 putative homeodomain transcription factor 1
 20867
 0.15
chr8_121714189_121714356 0.51 RP11-713M15.1
59221
 0.14
chr12_93834610_93834761 0.50 UBE2N
 ubiquitin-conjugating enzyme E2N
 347
 0.85
chr9_130792035_130792335 0.49 RP11-379C10.1
27456
 0.09
chr3_18470958_18471238 0.49 SATB1
 SATB homeobox 1
 4237
 0.24
chr7_13950741_13951075 0.49 ETV1
 ets variant 1
 75158
 0.12
chr13_41540748_41540928 0.49 ELF1
 E74-like factor 1 (ets domain transcription factor)
 15580
 0.18
chr5_80053748_80053899 0.48 DHFR
 dihydrofolate reductase
 103021
 0.06
chr3_107811334_107811485 0.48 CD47
 CD47 molecule
 1537
 0.55
chr1_226918876_226919104 0.48 ITPKB
 inositol-trisphosphate 3-kinase B
 6169
 0.25
chr2_196421409_196421560 0.47 SLC39A10
 solute carrier family 39 (zinc transporter), member 10
 19217
 0.24
chr7_152037629_152037780 0.46 ENSG00000253088
 .
 62161
 0.12
chr22_40738137_40738293 0.45 ADSL
 adenylosuccinate lyase
 4292
 0.22
chr11_3999951_4000538 0.45 STIM1
 stromal interaction molecule 1
 31671
 0.15
chr10_3709420_3709846 0.45 RP11-184A2.3
83626
 0.1
chr5_95150906_95151226 0.44 GLRX
 glutaredoxin (thioltransferase)
 7349
 0.16
chr19_33677663_33677957 0.44 LRP3
 low density lipoprotein receptor-related protein 3
 7680
 0.13
chr4_110571544_110571753 0.43 AC004067.5
41512
 0.14
chrX_19779868_19780019 0.43 SH3KBP1
 SH3-domain kinase binding protein 1
 14122
 0.29
chr15_64133458_64133609 0.43 HERC1
 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
 7392
 0.23
chr1_8489766_8489917 0.43 RP5-1115A15.1
4143
 0.22
chr9_132707070_132707482 0.42 RP11-409K20.6
11461
 0.19
chr9_33841783_33842038 0.42 ENSG00000200834
 .
 10934
 0.12
chr5_39185202_39185385 0.42 FYB
 FYN binding protein
 17836
 0.25
chr8_60240556_60240759 0.42 ENSG00000201763
 .
 127787
 0.06
chr1_100910954_100911247 0.42 RP5-837M10.4
40453
 0.15
chr7_8013996_8014418 0.42 AC006042.7
4673
 0.2
chr12_104868829_104868993 0.41 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 18132
 0.25
chr6_143189511_143189662 0.41 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 31402
 0.22
chrX_11784442_11784722 0.41 MSL3
 male-specific lethal 3 homolog (Drosophila)
 6835
 0.32
chr2_231508120_231508337 0.41 ENSG00000199791
 .
 56392
 0.11
chr9_33297269_33297449 0.41 NFX1
 nuclear transcription factor, X-box binding 1
 6816
 0.16
chr8_129551445_129551700 0.41 ENSG00000221351
 .
 280468
 0.01
chr11_47787493_47787651 0.41 FNBP4
 formin binding protein 4
 1281
 0.36
chr17_46189481_46189632 0.40 SNX11
 sorting nexin 11
 245
 0.86
chrX_41767743_41767943 0.40 ENSG00000251807
 .
 10759
 0.23
chr22_40307678_40307829 0.40 GRAP2
 GRB2-related adaptor protein 2
 10640
 0.17
chr1_185646518_185646683 0.40 ENSG00000201596
 .
 43286
 0.15
chr1_160611737_160611992 0.40 SLAMF1
 signaling lymphocytic activation molecule family member 1
 4947
 0.18
chr5_174911911_174912232 0.40 SFXN1
 sideroflexin 1
 6476
 0.23
chr18_74294702_74294853 0.40 LINC00908
 long intergenic non-protein coding RNA 908
 53903
 0.13
chr14_22548983_22549134 0.40 ENSG00000238634
 .
 61829
 0.14
chr1_40526792_40526943 0.39 CAP1
 CAP, adenylate cyclase-associated protein 1 (yeast)
 20313
 0.16
chr1_198589922_198590135 0.39 PTPRC
 protein tyrosine phosphatase, receptor type, C
 17773
 0.23
chr5_52020219_52020370 0.39 ITGA1
 integrin, alpha 1
 63436
 0.12
chr10_115625916_115626067 0.38 NHLRC2
 NHL repeat containing 2
 11571
 0.17
chr17_40609828_40609979 0.38 ATP6V0A1
 ATPase, H+ transporting, lysosomal V0 subunit a1
 959
 0.38
chr6_20406623_20406774 0.38 E2F3
 E2F transcription factor 3
 2664
 0.22
chr8_109486447_109486598 0.38 EMC2
 ER membrane protein complex subunit 2
 23862
 0.27
chr13_48820347_48820675 0.38 ITM2B
 integral membrane protein 2B
 13172
 0.25
chr2_197005876_197006039 0.38 RP11-347P5.1
10030
 0.2
chr15_92401400_92401706 0.37 SLCO3A1
 solute carrier organic anion transporter family, member 3A1
 4202
 0.3
chr8_87360864_87361033 0.37 WWP1
 WW domain containing E3 ubiquitin protein ligase 1
 5981
 0.29
chr7_114612569_114612720 0.37 MDFIC
 MyoD family inhibitor domain containing
 38720
 0.23
chr2_208483981_208484229 0.37 METTL21A
 methyltransferase like 21A
 4999
 0.21
chr4_78727930_78728100 0.37 CNOT6L
 CCR4-NOT transcription complex, subunit 6-like
 12202
 0.26
chr7_43909566_43909799 0.37 MRPS24
 mitochondrial ribosomal protein S24
 526
 0.74
chr20_50145944_50146095 0.36 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 13239
 0.27
chr1_111204078_111204246 0.36 ENSG00000221538
 .
 8509
 0.18
chr17_35960751_35960902 0.36 SYNRG
 synergin, gamma
 8603
 0.17
chr13_48793580_48793731 0.36 ITM2B
 integral membrane protein 2B
 13639
 0.25
chr8_81051643_81051794 0.36 RP11-92K15.1
16631
 0.2
chr4_87920133_87920357 0.36 AFF1
 AF4/FMR2 family, member 1
 7895
 0.28
chr12_14444158_14444309 0.36 ENSG00000265119
 .
 20044
 0.2
chr10_48461977_48462183 0.36 GDF10
 growth differentiation factor 10
 23104
 0.17
chr6_45420208_45420439 0.36 RUNX2
 runt-related transcription factor 2
 30101
 0.19
chr11_124495044_124495195 0.35 TBRG1
 transforming growth factor beta regulator 1
 2326
 0.2
chr6_15397672_15397823 0.35 JARID2
 jumonji, AT rich interactive domain 2
 3342
 0.33
chr6_159519338_159519692 0.35 TAGAP
 T-cell activation RhoGTPase activating protein
 53331
 0.11
chr16_53493564_53493875 0.35 RBL2
 retinoblastoma-like 2 (p130)
 9731
 0.16
chr7_6298731_6299016 0.35 CYTH3
 cytohesin 3
 13402
 0.18
chr4_90410089_90410240 0.35 RP11-115D19.1
62343
 0.15
chr9_37341093_37341244 0.35 ENSG00000206784
 .
 18912
 0.19
chr17_33372588_33372757 0.35 RFFL
 ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
 3302
 0.15
chr17_76006574_76006749 0.35 TNRC6C
 trinucleotide repeat containing 6C
 5524
 0.22
chrX_32217344_32217495 0.35 DMD
 dystrophin
 43833
 0.2
chr15_45001766_45002275 0.35 B2M
 beta-2-microglobulin
 1655
 0.29
chr8_19284492_19284750 0.35 SH2D4A
 SH2 domain containing 4A
 107520
 0.08
chr4_71961249_71961400 0.34 SLC4A4
 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
 91679
 0.08
chr9_21983229_21983380 0.34 CDKN2A
 cyclin-dependent kinase inhibitor 2A
 8207
 0.14
chr1_168412623_168412774 0.34 ENSG00000207974
 .
 67936
 0.11
chr5_96294843_96295052 0.34 LNPEP
 leucyl/cystinyl aminopeptidase
 792
 0.61
chr7_98975533_98975728 0.34 ARPC1B
 actin related protein 2/3 complex, subunit 1B, 41kDa
 3277
 0.16
chr16_57502364_57502515 0.34 POLR2C
 polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
 6140
 0.13
chr10_21788608_21788824 0.34 CASC10
 cancer susceptibility candidate 10
 2525
 0.18
chr11_118753719_118753870 0.34 CXCR5
 chemokine (C-X-C motif) receptor 5
 681
 0.52
chr8_95955710_95956126 0.34 TP53INP1
 tumor protein p53 inducible nuclear protein 1
 2717
 0.19
chrX_37655630_37655781 0.34 CYBB
 cytochrome b-245, beta polypeptide
 16388
 0.22
chr14_91879240_91879633 0.34 CCDC88C
 coiled-coil domain containing 88C
 4254
 0.28
chr3_101797096_101797247 0.34 ZPLD1
 zona pellucida-like domain containing 1
 20917
 0.26
chr1_220414900_220415051 0.33 RAB3GAP2
 RAB3 GTPase activating protein subunit 2 (non-catalytic)
 30256
 0.17
chr12_12672929_12673156 0.33 DUSP16
 dual specificity phosphatase 16
 1017
 0.63
chr2_204583285_204583561 0.33 CD28
 CD28 molecule
 12007
 0.23
chr3_17379285_17379436 0.33 TBC1D5
 TBC1 domain family, member 5
 68852
 0.14
chr15_59069056_59069207 0.33 FAM63B
 family with sequence similarity 63, member B
 5570
 0.16
chr1_160607664_160607901 0.33 SLAMF1
 signaling lymphocytic activation molecule family member 1
 9029
 0.16
chr18_2579117_2579268 0.33 NDC80
 NDC80 kinetochore complex component
 1344
 0.35
chr6_109357060_109357211 0.33 ENSG00000199944
 .
 23682
 0.16
chr7_130765782_130766079 0.33 LINC-PINT
 long intergenic non-protein coding RNA, p53 induced transcript
 7303
 0.22
chr6_37878002_37878153 0.33 ENSG00000200597
 .
 5272
 0.24
chr14_68758527_68759049 0.33 ENSG00000243546
 .
 55532
 0.15
chr2_225851954_225852161 0.33 ENSG00000263828
 .
 23200
 0.24
chrX_13106601_13106839 0.33 FAM9C
 family with sequence similarity 9, member C
 43919
 0.18
chr12_123844374_123844525 0.32 SBNO1
 strawberry notch homolog 1 (Drosophila)
 4926
 0.16
chrX_135769178_135769446 0.32 CD40LG
 CD40 ligand
 38926
 0.13
chr12_80249075_80249226 0.32 PPP1R12A
 protein phosphatase 1, regulatory subunit 12A
 17502
 0.16
chr4_54277446_54277597 0.32 FIP1L1
 factor interacting with PAPOLA and CPSF1
 16712
 0.22
chr15_45029426_45029577 0.32 TRIM69
 tripartite motif containing 69
 737
 0.62
chr2_234317301_234317452 0.32 DGKD
 diacylglycerol kinase, delta 130kDa
 20576
 0.16
chr17_48948425_48948576 0.32 TOB1
 transducer of ERBB2, 1
 3161
 0.2
chr2_149413727_149414080 0.32 EPC2
 enhancer of polycomb homolog 2 (Drosophila)
 10914
 0.3
chr5_110086965_110087116 0.32 SLC25A46
 solute carrier family 25, member 46
 3780
 0.27
chrX_78200075_78200274 0.32 P2RY10
 purinergic receptor P2Y, G-protein coupled, 10
 655
 0.83
chr8_119322107_119322258 0.32 AC023590.1
 Uncharacterized protein
 27701
 0.27
chr3_43390090_43390241 0.32 RP11-188P20.3
1030
 0.5
chr4_78736039_78736190 0.32 CNOT6L
 CCR4-NOT transcription complex, subunit 6-like
 4103
 0.31
chr18_68325321_68325472 0.32 GTSCR1
 Gilles de la Tourette syndrome chromosome region, candidate 1
 7416
 0.33
chr10_22894712_22894863 0.32 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
 14145
 0.29
chr5_169718242_169718475 0.32 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 6873
 0.23
chr17_73365257_73365429 0.32 RP11-16C1.2
4474
 0.12
chr4_149352672_149352823 0.31 NR3C2
 nuclear receptor subfamily 3, group C, member 2
 5265
 0.34
chr13_37030668_37030819 0.31 CCNA1
 cyclin A1
 24248
 0.21
chr17_42323284_42323440 0.31 AC003102.1
3874
 0.1
chr1_241840160_241840311 0.31 WDR64
 WD repeat domain 64
 6647
 0.23
chr1_100918680_100918971 0.31 RP5-837M10.4
32728
 0.17
chr4_140001799_140001950 0.31 ELF2
 E74-like factor 2 (ets domain transcription factor)
 3470
 0.19
chr13_52107424_52107667 0.31 INTS6-AS1
 INTS6 antisense RNA 1
 8149
 0.14
chr6_36005080_36005248 0.31 MAPK14
 mitogen-activated protein kinase 14
 8298
 0.19
chr14_61883865_61884124 0.31 PRKCH
 protein kinase C, eta
 25282
 0.21
chr22_44850826_44850977 0.31 LDOC1L
 leucine zipper, down-regulated in cancer 1-like
 43277
 0.18
chr12_67920194_67920345 0.30 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
 121849
 0.06
chr17_25784455_25784823 0.30 KSR1
 kinase suppressor of ras 1
 899
 0.6
chr5_130613996_130614147 0.30 CDC42SE2
 CDC42 small effector 2
 14278
 0.28
chr6_99938862_99939169 0.30 USP45
 ubiquitin specific peptidase 45
 8274
 0.18
chr5_130587781_130588081 0.30 CDC42SE2
 CDC42 small effector 2
 11771
 0.27
chr6_24957255_24957453 0.30 FAM65B
 family with sequence similarity 65, member B
 21166
 0.2
chr1_65475101_65475369 0.30 ENSG00000212257
 .
 13522
 0.19
chr14_61814414_61814719 0.30 PRKCH
 protein kinase C, eta
 43
 0.98
chr15_49999697_49999848 0.30 RP11-353B9.1
55436
 0.13
chr2_103016581_103016795 0.30 IL18RAP
 interleukin 18 receptor accessory protein
 18461
 0.14
chr1_198661100_198661367 0.30 RP11-553K8.5
25043
 0.23
chrX_30593744_30593895 0.30 CXorf21
 chromosome X open reading frame 21
 2142
 0.39
chr2_48557371_48557557 0.30 ENSG00000251889
 .
 10501
 0.22
chr2_145276991_145277142 0.30 ZEB2-AS1
 ZEB2 antisense RNA 1
 115
 0.87
chr2_169961679_169961830 0.30 AC007556.3
4501
 0.26
chr3_33086671_33086822 0.30 GLB1
 galactosidase, beta 1
 51538
 0.11
chr5_171368623_171368774 0.30 FBXW11
 F-box and WD repeat domain containing 11
 36062
 0.19
chr3_71410535_71410686 0.30 FOXP1
 forkhead box P1
 56699
 0.15
chr16_71914316_71914975 0.30 ZNF821
 zinc finger protein 821
 677
 0.52
chr5_100234402_100234890 0.29 ST8SIA4
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
 4272
 0.34
chr5_169718890_169719042 0.29 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 6265
 0.24
chr20_1639703_1639854 0.29 SIRPG
 signal-regulatory protein gamma
 1353
 0.36
chr6_88467574_88467725 0.29 ENSG00000238628
 .
 37016
 0.15
chr1_172670656_172670827 0.29 FASLG
 Fas ligand (TNF superfamily, member 6)
 42583
 0.18
chr12_52745258_52745409 0.29 KRT85
 keratin 85
 13073
 0.09
chrX_119740205_119740356 0.29 MCTS1
 malignant T cell amplified sequence 1
 2104
 0.31
chr6_12071674_12071825 0.29 HIVEP1
 human immunodeficiency virus type I enhancer binding protein 1
 54230
 0.16
chr22_41503197_41503348 0.29 ENSG00000221160
 .
 14755
 0.12
chr10_63150600_63150931 0.29 TMEM26
 transmembrane protein 26
 40325
 0.19
chr14_61844385_61844536 0.29 PRKCH
 protein kinase C, eta
 12952
 0.23
chr12_11919657_11920091 0.29 ETV6
 ets variant 6
 14439
 0.28
chr6_143165210_143165407 0.29 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 7124
 0.3
chr5_78556716_78556867 0.29 JMY
 junction mediating and regulatory protein, p53 cofactor
 24779
 0.17
chr1_203282441_203282646 0.29 ENSG00000202300
 .
 5684
 0.18
chr12_94545765_94545930 0.29 PLXNC1
 plexin C1
 3348
 0.28
chr10_124759466_124759617 0.29 IKZF5
 IKAROS family zinc finger 5 (Pegasus)
 8792
 0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZFHX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.2 0.6 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.5 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.1 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.6 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 0.4 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.2 GO:0090266 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.2 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1 0.2 GO:0007100 mitotic centrosome separation(GO:0007100)
0.1 0.3 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.2 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0042663 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.2 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.2 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.2 GO:0071636 positive regulation of transforming growth factor beta production(GO:0071636)
0.0 0.2 GO:0032695 negative regulation of interleukin-12 production(GO:0032695)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.0 GO:0002507 tolerance induction(GO:0002507)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.3 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0002888 positive regulation of myeloid leukocyte mediated immunity(GO:0002888)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.0 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.1 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0072124 glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0051532 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.2 GO:0048535 lymph node development(GO:0048535)
0.0 0.0 GO:0051497 negative regulation of actin filament bundle assembly(GO:0032232) negative regulation of stress fiber assembly(GO:0051497)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.0 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0045423 regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.6 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.5 GO:0045576 mast cell activation(GO:0045576)
0.0 0.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.0 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.0 GO:0002707 negative regulation of lymphocyte mediated immunity(GO:0002707)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.0 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.2 GO:0044409 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.1 GO:2000330 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.1 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.3 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:2001234 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.1 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:1904251 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.0 GO:1903306 negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.0 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0010988 regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0 0.0 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.0 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.0 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0048070 regulation of developmental pigmentation(GO:0048070)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.0 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.0 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.0 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070)
0.0 0.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.0 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.0 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.0 GO:0033079 immature T cell proliferation(GO:0033079)
0.0 0.0 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0006534 cysteine metabolic process(GO:0006534)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 1.0 GO:0006959 humoral immune response(GO:0006959)
0.0 0.2 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0060123 regulation of growth hormone secretion(GO:0060123)
0.0 0.2 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0051447 negative regulation of meiotic cell cycle(GO:0051447)
0.0 0.0 GO:0090224 regulation of spindle organization(GO:0090224)
0.0 0.1 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.5 GO:0070646 protein modification by small protein removal(GO:0070646)
0.0 0.0 GO:2000351 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.0 GO:0032261 purine nucleotide salvage(GO:0032261)
0.0 0.0 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.0 GO:0046950 cellular ketone body metabolic process(GO:0046950)
0.0 0.2 GO:0030317 sperm motility(GO:0030317)
0.0 0.0 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.1 GO:0006241 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.5 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.0 GO:0046132 pyrimidine ribonucleoside biosynthetic process(GO:0046132)
0.0 0.0 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.0 GO:0032328 alanine transport(GO:0032328)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0072512 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.0 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.2 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.6 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.0 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0042891 tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0 0.1 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0015669 gas transport(GO:0015669)
0.0 0.0 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.0 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.5 GO:0070688 MLL5-L complex(GO:0070688)
0.1 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0030175 filopodium(GO:0030175)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.0 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.3 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.8 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.8 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0060229 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0035240 dopamine binding(GO:0035240)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0099528 dopamine neurotransmitter receptor activity(GO:0004952) G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0070061 fructose binding(GO:0070061)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.2 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.2 GO:0043621 protein self-association(GO:0043621)
0.0 0.0 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.4 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.0 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.0 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.0 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.0 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.2 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.0 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.1 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.0 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters