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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZIC1

Z-value: 1.58

Motif logo

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Transcription factors associated with ZIC1

Gene Symbol Gene ID Gene Info
ZIC1
ENSG00000152977.5 ZIC1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ZIC1chr3_147130089_14713024029930.245780-0.684.3e-02Click!
ZIC1chr3_147136818_14713696997220.1917520.646.3e-02Click!
ZIC1chr3_147130587_14713073834910.230377-0.551.2e-01Click!
ZIC1chr3_147110427_14711057811800.4534210.521.5e-01Click!
ZIC1chr3_147111345_1471114962620.9095930.511.7e-01Click!

Activity of the ZIC1 motif across conditions

Conditions sorted by the z-value of the ZIC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr18_21441508_21442003 0.46 LAMA3
 laminin, alpha 3
 11049
 0.22
chr5_1494557_1494933 0.45 LPCAT1
 lysophosphatidylcholine acyltransferase 1
 29347
 0.18
chr1_109934550_109935130 0.44 SORT1
 sortilin 1
 1139
 0.45
chr12_43709758_43710210 0.41 ENSG00000215993
 .
 24601
 0.27
chr14_75735835_75736333 0.39 RP11-293M10.1
 Uncharacterized protein
 98
 0.95
chr4_124399950_124400344 0.37 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 79024
 0.12
chr7_48009158_48009388 0.37 HUS1
 HUS1 checkpoint homolog (S. pombe)
 9828
 0.19
chr16_53127962_53128318 0.36 CHD9
 chromodomain helicase DNA binding protein 9
 4932
 0.27
chr5_73536989_73537227 0.35 ENSG00000222551
 .
 30482
 0.23
chr15_70440007_70440428 0.34 ENSG00000200216
 .
 45358
 0.16
chr4_37666460_37666702 0.32 RELL1
 RELT-like 1
 422
 0.87
chr1_150136184_150136335 0.32 PLEKHO1
 pleckstrin homology domain containing, family O member 1
 7136
 0.15
chr20_23132592_23133523 0.32 ENSG00000201527
 .
 8551
 0.22
chr19_41926852_41927085 0.32 BCKDHA
 branched chain keto acid dehydrogenase E1, alpha polypeptide
 2046
 0.16
chr14_61568522_61568874 0.32 SLC38A6
 solute carrier family 38, member 6
 58830
 0.13
chr11_65259042_65259542 0.32 SCYL1
 SCY1-like 1 (S. cerevisiae)
 33256
 0.08
chr7_117468416_117468567 0.31 CTTNBP2
 cortactin binding protein 2
 36657
 0.22
chr12_66289441_66289878 0.31 RP11-366L20.2
 Uncharacterized protein
 13712
 0.17
chr9_71173939_71174218 0.31 TMEM252
 transmembrane protein 252
 18295
 0.25
chr11_12129395_12129640 0.30 MICAL2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 2621
 0.38
chr6_16773666_16773859 0.30 RP1-151F17.1
11619
 0.24
chr12_81102661_81102850 0.30 MYF6
 myogenic factor 6 (herculin)
 1478
 0.44
chr7_41046808_41047238 0.29 AC005160.3
231866
 0.02
chr11_115801802_115801953 0.29 ENSG00000239153
 .
 303974
 0.01
chr19_935300_935451 0.29 ARID3A
 AT rich interactive domain 3A (BRIGHT-like)
 2866
 0.12
chr18_19904044_19904557 0.29 ENSG00000238907
 .
 63761
 0.11
chr19_50284218_50285014 0.29 AP2A1
 adaptor-related protein complex 2, alpha 1 subunit
 14225
 0.07
chr2_172380569_172381265 0.29 CYBRD1
 cytochrome b reductase 1
 1328
 0.53
chr16_67168849_67169000 0.28 C16orf70
 chromosome 16 open reading frame 70
 11263
 0.08
chr8_38874641_38875005 0.28 ENSG00000207199
 .
 1379
 0.37
chr8_141129055_141129276 0.28 C8orf17
 chromosome 8 open reading frame 17
 185749
 0.03
chr10_110225723_110225990 0.28 ENSG00000222436
 .
 475212
 0.01
chr1_212106101_212106282 0.28 ENSG00000212187
 .
 92712
 0.06
chr18_61498762_61499118 0.27 SERPINB2
 serpin peptidase inhibitor, clade B (ovalbumin), member 2
 39986
 0.14
chr15_68992418_68992757 0.27 CORO2B
 coronin, actin binding protein, 2B
 68260
 0.12
chr1_45296298_45296558 0.27 PTCH2
 patched 2
 7496
 0.09
chr2_20795415_20795848 0.27 HS1BP3-IT1
 HS1BP3 intronic transcript 1 (non-protein coding)
 3323
 0.28
chr1_229161136_229161564 0.26 RP5-1061H20.5
201959
 0.02
chr11_10620459_10620776 0.26 MRVI1-AS1
 MRVI1 antisense RNA 1
 5873
 0.19
chr3_52904617_52904846 0.26 TMEM110
 transmembrane protein 110
 18016
 0.12
chr1_245215838_245216124 0.26 ENSG00000251754
 .
 8751
 0.17
chr6_6728512_6728665 0.26 LY86-AS1
 LY86 antisense RNA 1
 105584
 0.07
chr5_14203788_14204073 0.26 TRIO
 trio Rho guanine nucleotide exchange factor
 20023
 0.29
chr5_149976234_149976439 0.26 SYNPO
 synaptopodin
 4306
 0.19
chr22_38137524_38137675 0.26 TRIOBP
 TRIO and F-actin binding protein
 4636
 0.14
chr2_173145900_173146235 0.26 ENSG00000238572
 .
 125219
 0.05
chr12_94657868_94658081 0.26 PLXNC1
 plexin C1
 1677
 0.34
chr2_25208112_25208263 0.26 DNAJC27-AS1
 DNAJC27 antisense RNA 1
 13135
 0.13
chr3_53191576_53191739 0.26 PRKCD
 protein kinase C, delta
 1632
 0.35
chr6_16682943_16683094 0.26 RP1-151F17.1
78351
 0.11
chr3_66449033_66449184 0.26 ENSG00000241587
 .
 74829
 0.11
chr5_1386620_1386888 0.26 SLC6A3
 solute carrier family 6 (neurotransmitter transporter), member 3
 14668
 0.2
chr12_110310303_110310470 0.25 ENSG00000241413
 .
 6072
 0.15
chr4_97502612_97502891 0.25 ENSG00000201640
 .
 232562
 0.02
chr1_87615183_87615459 0.25 ENSG00000221222
 .
 1660
 0.51
chr17_54701720_54701923 0.25 NOG
 noggin
 30761
 0.23
chr14_92730704_92730855 0.25 ENSG00000201097
 .
 1267
 0.55
chr1_17559878_17560367 0.25 PADI1
 peptidyl arginine deiminase, type I
 272
 0.9
chr20_30156414_30156800 0.25 HM13-AS1
 HM13 antisense RNA 1
 4459
 0.13
chr2_237880972_237881333 0.25 ENSG00000202341
 .
 42796
 0.17
chr8_61862675_61863209 0.25 CLVS1
 clavesin 1
 106775
 0.07
chr6_38123150_38123303 0.25 ENSG00000200706
 .
 51824
 0.17
chr2_28182385_28182785 0.25 ENSG00000265321
 .
 36649
 0.16
chr1_230262720_230263119 0.25 GALNT2
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
 59901
 0.13
chr14_75406536_75406708 0.25 PGF
 placental growth factor
 15323
 0.13
chr1_17388211_17388464 0.24 SDHB
 succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
 7672
 0.18
chr19_10416474_10416677 0.24 ZGLP1
 zinc finger, GATA-like protein 1
 3884
 0.09
chr13_108520309_108520631 0.24 FAM155A
 family with sequence similarity 155, member A
 1387
 0.54
chr1_110776636_110776787 0.24 KCNC4
 potassium voltage-gated channel, Shaw-related subfamily, member 4
 22589
 0.12
chrX_13506892_13507043 0.24 EGFL6
 EGF-like-domain, multiple 6
 80757
 0.09
chr6_43806228_43806543 0.24 VEGFA
 vascular endothelial growth factor A
 64295
 0.1
chr17_10030593_10030821 0.24 GAS7
 growth arrest-specific 7
 12837
 0.2
chr2_60610274_60610606 0.24 ENSG00000200807
 .
 1300
 0.5
chr11_1845805_1845956 0.24 SYT8
 synaptotagmin VIII
 2829
 0.14
chr8_35719083_35719234 0.24 AC012215.1
 Uncharacterized protein
 69793
 0.14
chr6_134342442_134342593 0.24 SLC2A12
 solute carrier family 2 (facilitated glucose transporter), member 12
 31257
 0.19
chr6_151362493_151362728 0.24 ENSG00000221469
 .
 1503
 0.38
chr9_22170998_22171149 0.24 CDKN2B-AS1
 CDKN2B antisense RNA 1
 57396
 0.15
chr3_123337794_123338198 0.24 MYLK
 myosin light chain kinase
 1365
 0.44
chr5_138363011_138363258 0.24 CTB-46B19.2
14795
 0.16
chr12_48001731_48001929 0.23 RPAP3
 RNA polymerase II associated protein 3
 97939
 0.07
chr14_77249034_77249359 0.23 RP11-488C13.6
1335
 0.4
chr1_45292295_45292814 0.23 PTCH2
 patched 2
 3622
 0.11
chr4_141003180_141003333 0.23 RP11-392B6.1
45913
 0.17
chr13_61146576_61146871 0.23 ENSG00000223076
 .
 41019
 0.2
chr10_10563093_10563244 0.23 ENSG00000200849
 .
 288594
 0.01
chr21_16624814_16624965 0.23 NRIP1
 nuclear receptor interacting protein 1
 187568
 0.03
chr8_145078675_145078826 0.23 SPATC1
 spermatogenesis and centriole associated 1
 7832
 0.09
chr2_105941174_105941337 0.23 TGFBRAP1
 transforming growth factor, beta receptor associated protein 1
 5236
 0.18
chr10_31023932_31024083 0.23 SVILP1
 supervillin pseudogene 1
 39157
 0.18
chr2_178147224_178147445 0.23 NFE2L2
 nuclear factor, erythroid 2-like 2
 5171
 0.12
chr11_47963257_47963527 0.23 PTPRJ
 protein tyrosine phosphatase, receptor type, J
 38721
 0.15
chr2_65084933_65085167 0.23 ENSG00000199964
 .
 23759
 0.15
chr10_3793162_3793446 0.23 RP11-184A2.3
45
 0.98
chrX_13376029_13376315 0.23 ATXN3L
 ataxin 3-like
 37654
 0.19
chr2_16817031_16817182 0.23 FAM49A
 family with sequence similarity 49, member A
 12762
 0.3
chr1_66955749_66956137 0.23 SGIP1
 SH3-domain GRB2-like (endophilin) interacting protein 1
 43123
 0.18
chr21_44994556_44994959 0.23 HSF2BP
 heat shock transcription factor 2 binding protein
 83268
 0.08
chr10_31986594_31986822 0.23 ENSG00000222412
 .
 58356
 0.16
chr21_38856192_38856343 0.23 DYRK1A
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
 4820
 0.27
chr6_116878944_116879095 0.23 FAM26D
 family with sequence similarity 26, member D
 4106
 0.16
chr17_42619385_42619639 0.23 FZD2
 frizzled family receptor 2
 15413
 0.17
chr5_138414055_138414601 0.23 SIL1
 SIL1 nucleotide exchange factor
 35957
 0.15
chr11_119454813_119455176 0.23 RP11-196E1.3
24141
 0.19
chr17_1987997_1988266 0.23 RP11-667K14.5
4844
 0.12
chr14_35854447_35854675 0.23 NFKBIA
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
 18785
 0.23
chr18_61778130_61778281 0.22 SERPINB8
 serpin peptidase inhibitor, clade B (ovalbumin), member 8
 131163
 0.05
chr18_74211607_74211861 0.22 RP11-17M16.1
 uncharacterized protein LOC400658
 4257
 0.19
chr3_48597793_48598316 0.22 PFKFB4
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
 508
 0.63
chr2_123731892_123732043 0.22 ENSG00000221689
 .
 707824
 0.0
chr10_73627738_73628072 0.22 PSAP
 prosaposin
 16779
 0.19
chr4_185819150_185819410 0.22 ENSG00000263458
 .
 40314
 0.14
chr10_75827961_75828112 0.22 VCL
 vinculin
 15198
 0.2
chr2_235732945_235733096 0.22 SH3BP4
 SH3-domain binding protein 4
 127597
 0.06
chr15_99366117_99366417 0.22 ENSG00000264480
 .
 38612
 0.17
chr15_67316146_67316685 0.22 SMAD3
 SMAD family member 3
 39686
 0.2
chr17_36604180_36604649 0.22 ENSG00000260833
 .
 3518
 0.2
chr2_86033426_86033673 0.22 AC105053.3
8704
 0.16
chr6_34302944_34303141 0.22 NUDT3
 nudix (nucleoside diphosphate linked moiety X)-type motif 3
 57409
 0.11
chr2_160817652_160817857 0.22 LY75-CD302
 LY75-CD302 readthrough
 56533
 0.13
chr2_226982606_226982904 0.22 ENSG00000263363
 .
 540754
 0.0
chr11_68209017_68209227 0.22 LRP5
 low density lipoprotein receptor-related protein 5
 1781
 0.36
chr17_58648261_58648412 0.22 RP11-15E18.4
 Uncharacterized protein
 6428
 0.18
chr16_88989864_88990015 0.22 RP11-830F9.7
14225
 0.11
chr20_34761813_34761964 0.22 EPB41L1
 erythrocyte membrane protein band 4.1-like 1
 197
 0.93
chr6_18330462_18330649 0.22 ENSG00000200681
 .
 23245
 0.17
chr2_240171631_240171851 0.22 ENSG00000265215
 .
 55416
 0.1
chr12_20647309_20647460 0.21 RP11-284H19.1
124188
 0.06
chr20_58627325_58627485 0.21 C20orf197
 chromosome 20 open reading frame 197
 3575
 0.3
chr8_145017107_145017820 0.21 PLEC
 plectin
 663
 0.52
chr16_85363617_85363768 0.21 ENSG00000266307
 .
 23761
 0.19
chr11_114163796_114163947 0.21 NNMT
 nicotinamide N-methyltransferase
 2676
 0.32
chr10_81060018_81060169 0.21 ZMIZ1
 zinc finger, MIZ-type containing 1
 5882
 0.26
chr15_101690726_101690920 0.21 RP11-505E24.2
64552
 0.11
chr14_75922531_75922716 0.21 JDP2
 Jun dimerization protein 2
 23786
 0.17
chr5_73729978_73730173 0.21 ENSG00000244326
 .
 116264
 0.06
chr5_136899227_136899378 0.21 ENSG00000221612
 .
 30159
 0.2
chr11_117959166_117959354 0.21 TMPRSS4-AS1
 TMPRSS4 antisense RNA 1
 1752
 0.3
chr17_32563089_32563474 0.21 CCL2
 chemokine (C-C motif) ligand 2
 19023
 0.12
chr2_25805338_25805608 0.21 DTNB
 dystrobrevin, beta
 67620
 0.12
chr6_22025591_22025742 0.21 ENSG00000222515
 .
 60107
 0.16
chr2_27302580_27302731 0.21 EMILIN1
 elastin microfibril interfacer 1
 1220
 0.22
chr10_47659322_47659473 0.21 ANTXRL
 anthrax toxin receptor-like
 1148
 0.52
chr14_100882789_100883046 0.21 RP11-362L22.1
9675
 0.13
chr9_92750154_92750359 0.21 ENSG00000263967
 .
 35561
 0.25
chr15_38116485_38116636 0.21 TMCO5A
 transmembrane and coiled-coil domains 5A
 97580
 0.09
chr16_85796000_85796186 0.21 C16orf74
 chromosome 16 open reading frame 74
 11358
 0.1
chr2_74803113_74803707 0.21 LOXL3
 lysyl oxidase-like 3
 20593
 0.09
chr18_11893414_11893565 0.20 MPPE1
 metallophosphoesterase 1
 3554
 0.17
chr17_79396946_79397153 0.20 RP11-1055B8.7
 BAH and coiled-coil domain-containing protein 1
 8347
 0.11
chr1_235093577_235093777 0.20 ENSG00000239690
 .
 53744
 0.15
chr17_77999485_77999773 0.20 CTD-2529O21.2
1899
 0.27
chr2_85128601_85128752 0.20 TMSB10
 thymosin beta 10
 4073
 0.21
chrX_13269027_13269605 0.20 GS1-600G8.3
59455
 0.14
chr22_25797043_25797363 0.20 LRP5L
 low density lipoprotein receptor-related protein 5-like
 4141
 0.23
chr5_73092141_73092406 0.20 CTC-575I10.1
9957
 0.2
chr11_73100197_73100477 0.20 RP11-809N8.2
7144
 0.15
chr11_11438455_11438655 0.20 CSNK2A3
 casein kinase 2, alpha 3 polypeptide
 63651
 0.12
chr10_111650492_111650643 0.20 XPNPEP1
 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
 17010
 0.2
chr5_66000661_66000812 0.20 MAST4-IT1
 MAST4 intronic transcript 1 (non-protein coding)
 42577
 0.19
chr17_40063221_40063372 0.20 ACLY
 ATP citrate lyase
 11908
 0.12
chr3_24283691_24283842 0.20 THRB
 thyroid hormone receptor, beta
 76680
 0.12
chr11_123175979_123176130 0.20 ENSG00000200496
 .
 3956
 0.28
chr20_33159345_33159531 0.20 MAP1LC3A
 microtubule-associated protein 1 light chain 3 alpha
 12916
 0.17
chr3_47051591_47051826 0.20 NBEAL2
 neurobeachin-like 2
 4937
 0.21
chr1_16500642_16500847 0.20 RP11-276H7.3
14983
 0.1
chr1_230281309_230281781 0.20 GALNT2
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
 78527
 0.1
chr21_30688780_30689338 0.20 BACH1
 BTB and CNC homology 1, basic leucine zipper transcription factor 1
 10391
 0.18
chr11_67124730_67125439 0.20 POLD4
 polymerase (DNA-directed), delta 4, accessory subunit
 4067
 0.1
chr1_178027486_178027784 0.20 RASAL2
 RAS protein activator like 2
 35229
 0.22
chr20_49306472_49306623 0.20 FAM65C
 family with sequence similarity 65, member C
 1369
 0.41
chr10_104389775_104390433 0.20 TRIM8
 tripartite motif containing 8
 14149
 0.16
chr8_97872343_97872494 0.20 CPQ
 carboxypeptidase Q
 98950
 0.09
chr3_99129524_99129675 0.20 ENSG00000266030
 .
 43866
 0.2
chr18_42828323_42828591 0.20 SLC14A2
 solute carrier family 14 (urea transporter), member 2
 35497
 0.2
chr9_128289880_128290161 0.20 ENSG00000243845
 .
 14534
 0.21
chr2_36603812_36603963 0.20 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 20273
 0.27
chr8_102388155_102388449 0.19 ENSG00000239211
 .
 21859
 0.22
chr6_11324269_11324660 0.19 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 58068
 0.14
chr13_72406066_72406303 0.19 DACH1
 dachshund homolog 1 (Drosophila)
 34723
 0.24
chr2_65581059_65581210 0.19 SPRED2
 sprouty-related, EVH1 domain containing 2
 9214
 0.23
chr14_101131713_101131864 0.19 DLK1
 delta-like 1 homolog (Drosophila)
 60254
 0.06
chr17_56386632_56386867 0.19 BZRAP1
 benzodiazepine receptor (peripheral) associated protein 1
 825
 0.48
chr3_11243097_11243459 0.19 HRH1
 histamine receptor H1
 24439
 0.24
chr13_114822172_114822499 0.19 RASA3
 RAS p21 protein activator 3
 21103
 0.23
chr13_80934002_80934271 0.19 ENSG00000202398
 .
 9533
 0.26
chr22_18042634_18042900 0.19 SLC25A18
 solute carrier family 25 (glutamate carrier), member 18
 372
 0.87
chr1_192800189_192800340 0.19 RGS2
 regulator of G-protein signaling 2, 24kDa
 22093
 0.22
chr8_142156822_142157077 0.19 DENND3
 DENN/MADD domain containing 3
 5647
 0.21
chr11_11990885_11991036 0.19 DKK3
 dickkopf WNT signaling pathway inhibitor 3
 39170
 0.2
chr17_56584843_56584994 0.19 MTMR4
 myotubularin related protein 4
 6479
 0.13
chr18_9838569_9838743 0.19 ENSG00000252680
 .
 6187
 0.19
chr17_57863390_57863857 0.19 RP11-619I22.1
1449
 0.37
chr16_11373189_11373514 0.19 PRM1
 protamine 1
 1856
 0.15
chr5_157295124_157295340 0.19 CLINT1
 clathrin interactor 1
 9049
 0.23
chr10_104953660_104953838 0.19 NT5C2
 5'-nucleotidase, cytosolic II
 693
 0.72
chr16_55542103_55542255 0.19 LPCAT2
 lysophosphatidylcholine acyltransferase 2
 731
 0.71
chr9_132096828_132097338 0.19 ENSG00000242281
 .
 35657
 0.16
chr1_73100855_73101006 0.19 ENSG00000212366
 .
 82522
 0.12
chr11_36488512_36488753 0.19 RP11-219O3.2
40960
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ZIC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0018101 protein citrullination(GO:0018101)
0.1 0.2 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.2 GO:0007028 cytoplasm organization(GO:0007028)
0.1 0.2 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.2 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0060087 relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.2 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.1 GO:0032351 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.1 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0051852 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.2 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.0 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0014052 gamma-aminobutyric acid secretion(GO:0014051) regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0045978 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0003309 type B pancreatic cell differentiation(GO:0003309)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.0 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0003351 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.0 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.0 GO:0034776 response to histamine(GO:0034776)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.2 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.0 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0071071 regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.1 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0071320 cellular response to cAMP(GO:0071320)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.2 GO:0010894 negative regulation of steroid biosynthetic process(GO:0010894)
0.0 0.1 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.1 GO:0021781 glial cell fate commitment(GO:0021781)
0.0 0.0 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0071295 cellular response to vitamin(GO:0071295)
0.0 0.0 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 0.1 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.0 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0031269 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.0 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.0 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.0 GO:0046881 positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.0 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0001865 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.0 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.0 GO:0009191 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0032329 serine transport(GO:0032329)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0090398 cellular senescence(GO:0090398)
0.0 0.0 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0010039 response to iron ion(GO:0010039)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.0 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.0 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.1 GO:0042116 macrophage activation(GO:0042116)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.0 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.0 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 0.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0031430 M band(GO:0031430)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.0 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.0 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.0 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0000036 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0015368 calcium:cation antiporter activity(GO:0015368)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.0 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0030552 cAMP binding(GO:0030552)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.0 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.0 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway