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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZKSCAN3

Z-value: 1.44

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Transcription factors associated with ZKSCAN3

Gene Symbol	Gene ID	Gene Info
ZKSCAN3 Ensembl NCBI GeneCards UniProt	ENSG00000189298.9	ZKSCAN3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ZKSCAN3	chr6_28318404_28318713	831	0.531891	0.66	5.5e-02	Click!
ZKSCAN3	chr6_28318919_28319190	1327	0.348212	0.54	1.3e-01	Click!
ZKSCAN3	chr6_28318026_28318177	374	0.819170	0.44	2.3e-01	Click!
ZKSCAN3	chr6_28317244_28317413	363	0.828791	0.27	4.8e-01	Click!
ZKSCAN3	chr6_28317523_28317674	93	0.958716	0.05	8.9e-01	Click!

Activity of the ZKSCAN3 motif across conditions

Conditions sorted by the z-value of the ZKSCAN3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_14610353_14610666	2.07	FAM107B	family with sequence similarity 107, member B	3520	0.31
chr9_100866127_100866462	1.53	TRIM14	tripartite motif containing 14	11451	0.18
chr11_64013353_64013610	0.94	RP11-783K16.5		45	0.65
chr1_211509622_211509899	0.92	TRAF5	TNF receptor-associated factor 5	9581	0.25
chr1_26100660_26100867	0.85	SEPN1	selenoprotein N, 1	25904	0.11
chr14_50563249_50563678	0.81	C14orf183	chromosome 14 open reading frame 183	4102	0.18
chr8_37748769_37748986	0.79	RAB11FIP1	RAB11 family interacting protein 1 (class I)	8095	0.14
chr4_100766407_100766703	0.79	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	28552	0.18
chr14_93159663_93159814	0.78	LGMN	legumain	24066	0.21
chr1_92940802_92940965	0.78	GFI1	growth factor independent 1 transcription repressor	8628	0.26
chr2_227702908_227703080	0.70	RHBDD1	rhomboid domain containing 1	730	0.71
chr1_25361714_25361887	0.70	ENSG00000264371	.	11806	0.23
chr16_57056402_57056553	0.69	NLRC5	NLR family, CARD domain containing 5	1852	0.27
chr2_97167178_97167382	0.69	NEURL3	neuralized E3 ubiquitin protein ligase 3	619	0.73
chr20_4789979_4790248	0.68	RASSF2	Ras association (RalGDS/AF-6) domain family member 2	5656	0.22
chr20_56193901_56194158	0.67	ZBP1	Z-DNA binding protein 1	1421	0.48
chr1_211526157_211526486	0.67	TRAF5	TNF receptor-associated factor 5	6615	0.27
chr11_73680269_73680439	0.66	RP11-167N4.2		978	0.46
chr15_60688686_60688869	0.65	ANXA2	annexin A2	760	0.75
chr15_64720015_64720166	0.65	TRIP4	thyroid hormone receptor interactor 4	3776	0.14
chr9_135363597_135363846	0.64	ENSG00000252521	.	66693	0.1
chr22_40327971_40328220	0.63	GRAP2	GRB2-related adaptor protein 2	5454	0.19
chr17_71589495_71589717	0.62	RP11-277J6.2		47559	0.14
chr11_73684050_73684451	0.62	RP11-167N4.2		2918	0.19
chr12_14577482_14577735	0.62	ATF7IP	activating transcription factor 7 interacting protein	913	0.66
chr10_15009390_15009541	0.61	MEIG1	meiosis/spermiogenesis associated 1	1027	0.53
chr2_136891083_136891299	0.61	CXCR4	chemokine (C-X-C motif) receptor 4	15456	0.27
chr19_682192_682343	0.61	FSTL3	follistatin-like 3 (secreted glycoprotein)	4325	0.11
chr14_99678734_99678885	0.61	AL109767.1		50476	0.13
chr4_89517359_89517510	0.58	HERC3	HECT and RLD domain containing E3 ubiquitin protein ligase 3	2905	0.24
chr11_73095605_73095891	0.58	RELT	RELT tumor necrosis factor receptor	8035	0.15
chr5_118607191_118607349	0.58	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	2821	0.26
chr3_9821453_9821979	0.58	CAMK1	calcium/calmodulin-dependent protein kinase I	10040	0.09
chr1_101749629_101749820	0.57	RP4-575N6.5		41010	0.13
chr1_67727636_67727815	0.57	ENSG00000252116	.	5684	0.17
chr7_150178587_150178758	0.56	GIMAP8	GTPase, IMAP family member 8	30954	0.13
chr15_28382300_28382484	0.56	HERC2	HECT and RLD domain containing E3 ubiquitin protein ligase 2	37177	0.18
chr3_185313043_185313423	0.56	SENP2	SUMO1/sentrin/SMT3 specific peptidase 2	9150	0.23
chr1_26873022_26873700	0.56	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	1018	0.45
chr9_137039448_137039599	0.56	ENSG00000221676	.	9837	0.2
chr6_112133106_112133257	0.55	FYN	FYN oncogene related to SRC, FGR, YES	8100	0.29
chr13_30950886_30951061	0.55	KATNAL1	katanin p60 subunit A-like 1	69352	0.11
chr3_15503071_15503367	0.55	EAF1-AS1	EAF1 antisense RNA 1	10110	0.12
chr17_60872822_60872973	0.55	MARCH10	membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase	11104	0.24
chr7_37382804_37383115	0.55	ELMO1	engulfment and cell motility 1	176	0.96
chr9_139423606_139423897	0.54	ENSG00000263403	.	9673	0.09
chr19_7702843_7703102	0.53	STXBP2	syntaxin binding protein 2	959	0.26
chr15_55514367_55514559	0.53	RSL24D1	ribosomal L24 domain containing 1	25198	0.18
chr14_61831663_61831831	0.53	PRKCH	protein kinase C, eta	3955	0.27
chr15_31134475_31134626	0.53	ENSG00000221379	.	41041	0.12
chr14_56582946_56583243	0.52	PELI2	pellino E3 ubiquitin protein ligase family member 2	1438	0.49
chr14_35303784_35304022	0.52	ENSG00000251726	.	10663	0.17
chr2_241562052_241562405	0.52	GPR35	G protein-coupled receptor 35	2434	0.21
chr11_44631349_44631561	0.52	RP11-58K22.4		1804	0.34
chr9_20378989_20379416	0.51	MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	3265	0.26
chr20_8116239_8116390	0.51	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)	3012	0.36
chr15_64260424_64260713	0.51	RP11-111E14.1		40095	0.15
chr9_129159177_129159360	0.50	ENSG00000253079	.	11421	0.2
chr14_77234089_77234240	0.50	VASH1	vasohibin 1	5492	0.2
chr20_55059757_55060025	0.49	ENSG00000238294	.	9192	0.13
chr13_41576048_41576351	0.49	ELF1	E74-like factor 1 (ets domain transcription factor)	17251	0.19
chr19_6766080_6766650	0.49	SH2D3A	SH2 domain containing 3A	1081	0.38
chr3_170942262_170942413	0.49	TNIK	TRAF2 and NCK interacting kinase	1163	0.63
chrX_53740602_53740909	0.49	HUWE1	HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase	27082	0.23
chr19_39728024_39728175	0.48	IFNL3	interferon, lambda 3	7547	0.12
chr3_183259605_183259756	0.48	KLHL6-AS1	KLHL6 antisense RNA 1	6843	0.17
chr12_57865222_57865373	0.48	ARHGAP9	Rho GTPase activating protein 9	3420	0.1
chr14_34512264_34512415	0.48	EGLN3-AS1	EGLN3 antisense RNA 1	3036	0.35
chr17_7779861_7780054	0.47	CHD3	chromodomain helicase DNA binding protein 3	8167	0.09
chr14_89977838_89978024	0.47	FOXN3	forkhead box N3	17402	0.19
chr4_6916161_6916458	0.46	TBC1D14	TBC1 domain family, member 14	4334	0.22
chr7_4748966_4749117	0.46	ENSG00000238781	.	19930	0.18
chr17_42326114_42326265	0.46	AC003102.1		1047	0.29
chr2_39472617_39472990	0.46	CDKL4	cyclin-dependent kinase-like 4	16130	0.19
chr2_118771117_118771268	0.46	CCDC93	coiled-coil domain containing 93	517	0.7
chr8_818924_819075	0.46	ERICH1-AS1	ERICH1 antisense RNA 1	14199	0.29
chr5_14587040_14587260	0.45	FAM105A	family with sequence similarity 105, member A	5266	0.28
chr21_47335720_47335871	0.45	PRED62	Uncharacterized protein	16682	0.18
chr20_1677648_1677799	0.45	ENSG00000242348	.	30717	0.14
chr3_122512892_122513151	0.45	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1	350	0.67
chr17_17209430_17209581	0.45	NT5M	5',3'-nucleotidase, mitochondrial	2856	0.24
chr3_52267134_52267345	0.45	TLR9	TLR9	2033	0.17
chr11_35073040_35073191	0.45	PDHX	pyruvate dehydrogenase complex, component X	73784	0.08
chr14_22886920_22887071	0.44	ENSG00000251002	.	14724	0.12
chr21_47971487_47971638	0.44	ENSG00000272283	.	15853	0.17
chr7_138777169_138777799	0.44	ZC3HAV1	zinc finger CCCH-type, antiviral 1	13471	0.2
chr1_1148836_1149071	0.44	TNFRSF4	tumor necrosis factor receptor superfamily, member 4	559	0.53
chr18_13313200_13313369	0.44	LDLRAD4	low density lipoprotein receptor class A domain containing 4	35182	0.14
chr9_34122816_34123204	0.44	DCAF12	DDB1 and CUL4 associated factor 12	2715	0.22
chr18_21601039_21601542	0.43	TTC39C	tetratricopeptide repeat domain 39C	4692	0.2
chr1_65408943_65409111	0.43	JAK1	Janus kinase 1	23160	0.22
chr1_160654931_160655551	0.43	RP11-404F10.2		11929	0.15
chr21_34561335_34561486	0.43	C21orf54	chromosome 21 open reading frame 54	18869	0.14
chr4_2837699_2838048	0.43	ADD1	adducin 1 (alpha)	7711	0.2
chr15_60883775_60883968	0.43	RORA	RAR-related orphan receptor A	869	0.66
chr12_62998741_62998934	0.43	ENSG00000199179	.	1371	0.28
chr1_205884511_205884662	0.43	RP4-681L3.2		19670	0.17
chr1_67426336_67426573	0.43	MIER1	mesoderm induction early response 1, transcriptional regulator	30528	0.16
chr21_36391287_36391723	0.43	RUNX1	runt-related transcription factor 1	29957	0.26
chr5_56025506_56025889	0.42	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	85704	0.08
chr19_19630373_19630524	0.42	NDUFA13	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	3409	0.12
chr1_89667140_89667505	0.42	GBP4	guanylate binding protein 4	2707	0.26
chr4_6918676_6918943	0.42	TBC1D14	TBC1 domain family, member 14	6834	0.19
chr1_98380116_98380267	0.41	DPYD	dihydropyrimidine dehydrogenase	6362	0.32
chr5_11234617_11234797	0.41	ENSG00000207312	.	207395	0.03
chr7_134852339_134852490	0.41	RP11-134L10.1		741	0.55
chr16_25077360_25077511	0.41	LCMT1	leucine carboxyl methyltransferase 1	45615	0.14
chr17_2236873_2237024	0.41	TSR1	TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)	2803	0.13
chr22_21960363_21960532	0.41	YDJC	YdjC homolog (bacterial)	23878	0.08
chr15_66065362_66065523	0.40	RP11-16E23.3		5706	0.18
chr13_42895024_42895175	0.40	AKAP11	A kinase (PRKA) anchor protein 11	48810	0.18
chr1_231171258_231171409	0.40	FAM89A	family with sequence similarity 89, member A	4659	0.18
chr1_12242763_12243127	0.40	ENSG00000263676	.	8825	0.16
chr12_7063873_7064421	0.40	PTPN6	protein tyrosine phosphatase, non-receptor type 6	3609	0.07
chr20_58515754_58515905	0.40	FAM217B	family with sequence similarity 217, member B	335	0.59
chr13_99952051_99952321	0.40	GPR183	G protein-coupled receptor 183	7473	0.21
chr1_206809391_206809612	0.40	DYRK3	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3	327	0.63
chr17_58041513_58041664	0.40	RNFT1	ring finger protein, transmembrane 1	492	0.75
chr9_97429931_97430112	0.40	FBP1	fructose-1,6-bisphosphatase 1	27490	0.19
chr3_43236741_43236892	0.39	ENSG00000222331	.	15547	0.22
chr1_175166883_175167095	0.39	KIAA0040	KIAA0040	4910	0.3
chr9_114426841_114427100	0.39	GNG10	guanine nucleotide binding protein (G protein), gamma 10	3355	0.21
chr17_44218651_44218858	0.39	ENSG00000252698	.	13992	0.17
chr2_205834532_205835011	0.38	PARD3B	par-3 family cell polarity regulator beta	424048	0.01
chr9_126763063_126763261	0.38	LHX2	LIM homeobox 2	787	0.6
chr11_117198965_117199116	0.38	CEP164	centrosomal protein 164kDa	221	0.57
chrX_153231291_153231484	0.38	HCFC1-AS1	HCFC1 antisense RNA 1	3389	0.11
chr15_42181166_42181317	0.38	RP11-23P13.6		3750	0.13
chr15_60828599_60828948	0.38	CTD-2501E16.2		6601	0.21
chr17_56361902_56362063	0.38	MPO	myeloperoxidase	3686	0.16
chr15_30456809_30456986	0.38	ENSG00000221785	.	19817	0.12
chr11_32610462_32610653	0.38	EIF3M	eukaryotic translation initiation factor 3, subunit M	575	0.82
chr11_1606465_1606821	0.37	KRTAP5-1	keratin associated protein 5-1	130	0.93
chr1_47181224_47181375	0.37	EFCAB14	EF-hand calcium binding domain 14	3437	0.21
chr7_96651846_96652002	0.37	DLX5	distal-less homeobox 5	2338	0.25
chr1_35897155_35897306	0.37	ENSG00000202129	.	3736	0.22
chr8_53851916_53852182	0.37	NPBWR1	neuropeptides B/W receptor 1	1058	0.63
chr5_171061383_171061534	0.37	ENSG00000264303	.	136076	0.04
chr6_35653753_35653924	0.37	FKBP5	FK506 binding protein 5	2854	0.19
chr4_16124268_16124434	0.36	PROM1	prominin 1	38350	0.16
chr3_59995792_59996170	0.36	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	38398	0.24
chr15_32665699_32665938	0.36	ENSG00000221444	.	19855	0.11
chr19_4638499_4638663	0.36	TNFAIP8L1	tumor necrosis factor, alpha-induced protein 8-like 1	949	0.43
chr6_24918083_24918272	0.36	FAM65B	family with sequence similarity 65, member B	6982	0.24
chr3_9440127_9440389	0.36	SETD5-AS1	SETD5 antisense RNA 1	5	0.93
chr3_9885266_9885439	0.36	RPUSD3	RNA pseudouridylate synthase domain containing 3	274	0.82
chr20_35573807_35573970	0.36	SAMHD1	SAM domain and HD domain 1	6223	0.23
chr20_30607376_30607540	0.35	CCM2L	cerebral cavernous malformation 2-like	437	0.74
chr2_65295203_65295373	0.35	CEP68	centrosomal protein 68kDa	11689	0.17
chr15_30472324_30472499	0.35	ENSG00000221785	.	35331	0.11
chr1_90206501_90206652	0.35	ENSG00000239176	.	27301	0.18
chr10_32216291_32216562	0.35	ARHGAP12	Rho GTPase activating protein 12	1302	0.55
chr7_142500079_142500230	0.35	PRSS3P2	protease, serine, 3 pseudogene 2	19023	0.16
chr2_106394710_106394861	0.34	NCK2	NCK adaptor protein 2	32597	0.22
chr2_161945197_161945348	0.34	TANK	TRAF family member-associated NFKB activator	48147	0.16
chr17_56394632_56394843	0.34	BZRAP1	benzodiazepine receptor (peripheral) associated protein 1	6636	0.12
chr6_149794191_149794357	0.34	ZC3H12D	zinc finger CCCH-type containing 12D	9995	0.17
chr21_43948338_43948579	0.34	SLC37A1	solute carrier family 37 (glucose-6-phosphate transporter), member 1	13824	0.13
chr11_114030278_114030531	0.34	ENSG00000221112	.	72753	0.1
chr11_125461625_125461796	0.33	STT3A	STT3A, subunit of the oligosaccharyltransferase complex (catalytic)	103	0.9
chr18_8602838_8602989	0.33	RAB12	RAB12, member RAS oncogene family	6530	0.22
chr9_34981335_34981528	0.33	DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	8207	0.15
chr6_15399373_15399540	0.33	JARID2	jumonji, AT rich interactive domain 2	1633	0.48
chr2_240673435_240673899	0.33	AC093802.1	Uncharacterized protein	10887	0.29
chr2_61243941_61244148	0.33	PUS10	pseudouridylate synthase 10	284	0.51
chr19_21646642_21646886	0.33	ZNF429	zinc finger protein 429	41602	0.16
chr1_27686480_27686799	0.33	MAP3K6	mitogen-activated protein kinase kinase kinase 6	3677	0.14
chrX_43295883_43296068	0.33	MAOA	monoamine oxidase A	219492	0.02
chr12_53024160_53024311	0.33	KRT73	keratin 73	11892	0.11
chr2_103036026_103036177	0.33	IL18RAP	interleukin 18 receptor accessory protein	45	0.97
chr1_26635107_26635385	0.33	UBXN11	UBX domain protein 11	1766	0.23
chr16_75123794_75123945	0.33	ZNRF1	zinc and ring finger 1, E3 ubiquitin protein ligase	14813	0.15
chr4_78079689_78079921	0.33	CCNG2	cyclin G2	226	0.94
chr12_12028552_12028703	0.33	ETV6	ets variant 6	10244	0.3
chr3_5047856_5048016	0.33	BHLHE40-AS1	BHLHE40 antisense RNA 1	26290	0.17
chr18_2884812_2884995	0.33	RP11-737O24.5		36061	0.12
chr7_110650904_110651055	0.32	LRRN3	leucine rich repeat neuronal 3	80083	0.1
chr19_2701835_2702122	0.32	GNG7	guanine nucleotide binding protein (G protein), gamma 7	729	0.53
chr9_36666940_36667091	0.32	MELK	maternal embryonic leucine zipper kinase	94107	0.08
chr20_47365648_47365892	0.32	ENSG00000251876	.	9785	0.28
chr2_234150632_234150905	0.32	ATG16L1	autophagy related 16-like 1 (S. cerevisiae)	9449	0.15
chr2_43382252_43382437	0.32	ENSG00000207087	.	63712	0.12
chr8_144075541_144075692	0.32	LY6E	lymphocyte antigen 6 complex, locus E	23783	0.15
chr16_23464322_23464473	0.32	COG7	component of oligomeric golgi complex 7	104	0.95
chrX_147701487_147701638	0.32	AFF2-IT1	AFF2 intronic transcript 1 (non-protein coding)	73163	0.11
chr19_12936277_12936463	0.32	CTD-2265O21.3		155	0.86
chr1_161097729_161097968	0.32	DEDD	death effector domain containing	2779	0.1
chr20_19918143_19918294	0.32	RIN2	Ras and Rab interactor 2	48008	0.15
chr3_52331644_52331795	0.32	ENSG00000242797	.	1211	0.27
chr2_111610296_111610719	0.31	ACOXL	acyl-CoA oxidase-like	47611	0.18
chr6_157304957_157305108	0.31	ARID1B	AT rich interactive domain 1B (SWI1-like)	82525	0.11
chr14_89925929_89926200	0.31	FOXN3	forkhead box N3	34331	0.15
chr19_30557968_30558119	0.31	URI1	URI1, prefoldin-like chaperone	54713	0.17
chr12_117534939_117535195	0.31	TESC	tescalcin	2184	0.41
chr16_3554613_3554882	0.31	CLUAP1	clusterin associated protein 1	2703	0.18
chr7_143005618_143005769	0.31	CLCN1	chloride channel, voltage-sensitive 1	7526	0.1
chr14_107198967_107199211	0.31	IGHV3-72	immunoglobulin heavy variable 3-72	382	0.58
chr14_23018397_23018864	0.31	AE000662.92	Uncharacterized protein	6904	0.11
chr2_98347856_98348007	0.31	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	2938	0.25
chr6_167508030_167508365	0.31	CCR6	chemokine (C-C motif) receptor 6	17098	0.18

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.4	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.2	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.2	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.2	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.3	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.1	0.2	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.1	0.2	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.1	0.2	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.2	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.3	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.5	GO:0010324	phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0	0.5	GO:0000303	response to superoxide(GO:0000303)
0.0	0.1	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.2	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.2	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.4	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.1	GO:0021780	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.4	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:2000328	T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.2	GO:0031000	response to caffeine(GO:0031000)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0060433	bronchus development(GO:0060433)
0.0	0.2	GO:0016446	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.2	GO:0051597	response to methylmercury(GO:0051597)
0.0	0.2	GO:0015012	heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0	0.1	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.1	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.1	GO:0043324	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.0	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.2	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.1	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0	0.1	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0031065	regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.0	0.2	GO:0050860	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.0	GO:1904019	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.0	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.0	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.1	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.1	GO:0051299	centrosome separation(GO:0051299)
0.0	0.0	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0032402	melanosome transport(GO:0032402)
0.0	0.1	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.0	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.0	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.2	GO:0044409	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0030851	granulocyte differentiation(GO:0030851)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.0	GO:0060685	regulation of prostatic bud formation(GO:0060685)
0.0	0.1	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.2	GO:0050853	B cell receptor signaling pathway(GO:0050853)
0.0	0.1	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.0	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0032367	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0051461	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.4	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.1	GO:0045446	endothelial cell differentiation(GO:0045446)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.6	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.2	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	0.1	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.1	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.0	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.1	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.4	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0000800	lateral element(GO:0000800)
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.2	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.2	GO:0070820	tertiary granule(GO:0070820)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.5	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.3	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.2	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.0	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.0	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.0	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.2	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.8	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.2	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.2	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.0	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.1	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.3	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.0	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.0	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.0	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.0	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.4	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.1	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.3	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.5	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.1	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.0	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.8	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.3	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.5	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.5	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.3	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.3	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.4	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.3	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.5	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.7	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.4	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.2	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.0	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.2	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage