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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZNF143

Z-value: 1.65

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Transcription factors associated with ZNF143

Gene Symbol	Gene ID	Gene Info
ZNF143 Ensembl NCBI GeneCards UniProt	ENSG00000166478.5	ZNF143

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ZNF143	chr11_9511208_9511359	22761	0.140938	0.79	1.1e-02	Click!
ZNF143	chr11_9481615_9481873	122	0.691450	-0.79	1.1e-02	Click!
ZNF143	chr11_9556875_9557026	22906	0.138514	0.77	1.4e-02	Click!
ZNF143	chr11_9510681_9510832	23288	0.139671	0.71	3.4e-02	Click!
ZNF143	chr11_9532170_9532321	1799	0.327001	-0.66	5.5e-02	Click!

Activity of the ZNF143 motif across conditions

Conditions sorted by the z-value of the ZNF143 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_41912974_41913725	1.46	MGA	MGA, MAX dimerization protein	385	0.85
chr1_150510557_150510858	1.43	ADAMTSL4	ADAMTS-like 4	11177	0.08
chr9_132236336_132236633	1.25	ENSG00000264298	.	4351	0.26
chr8_37556598_37557288	1.17	ZNF703	zinc finger protein 703	3674	0.16
chr8_49341467_49342503	1.03	ENSG00000252710	.	121395	0.06
chr16_85424724_85424875	1.02	RP11-680G10.1	Uncharacterized protein	33730	0.18
chr18_21464195_21464346	1.02	LAMA3	laminin, alpha 3	467	0.84
chr1_8272810_8272977	1.00	ENSG00000200975	.	6236	0.24
chr18_42179529_42179680	0.91	SETBP1	SET binding protein 1	80534	0.12
chr16_88366428_88366870	0.89	ZNF469	zinc finger protein 469	127230	0.05
chr10_104385999_104386279	0.88	TRIM8	tripartite motif containing 8	18114	0.15
chr16_56884007_56884388	0.86	ENSG00000207649	.	8233	0.14
chr21_17959428_17959579	0.85	ENSG00000207863	.	3054	0.31
chr2_238804572_238804786	0.85	ENSG00000263723	.	26132	0.17
chr2_43301822_43302026	0.83	ENSG00000207087	.	16708	0.28
chr2_19340414_19340714	0.83	ENSG00000266738	.	207626	0.03
chr1_203524952_203525250	0.83	OPTC	opticin	60003	0.11
chr17_14821652_14821803	0.82	ENSG00000238806	.	319473	0.01
chr17_36604180_36604649	0.80	ENSG00000260833	.	3518	0.2
chr11_35551231_35551382	0.77	PAMR1	peptidase domain containing associated with muscle regeneration 1	542	0.83
chr1_32038621_32038861	0.77	RP11-73M7.1		2433	0.21
chr11_72500407_72500904	0.76	STARD10	StAR-related lipid transfer (START) domain containing 10	3643	0.14
chr9_130817852_130818146	0.76	RP11-379C10.1		1642	0.22
chr9_37966595_37966746	0.75	ENSG00000251745	.	29905	0.19
chr1_17908500_17908722	0.73	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like	1563	0.51
chr3_138581340_138581807	0.73	PIK3CB	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta	27793	0.2
chr13_110161938_110162089	0.72	LINC00676	long intergenic non-protein coding RNA 676	218616	0.02
chr21_37583097_37583248	0.72	ENSG00000265882	.	2964	0.22
chr14_23316976_23317711	0.71	ENSG00000212335	.	4594	0.09
chr17_9331018_9331169	0.70	AC087501.1		24421	0.18
chr1_230379381_230379663	0.70	RP5-956O18.2		24707	0.21
chr15_48919832_48919983	0.70	FBN1	fibrillin 1	18011	0.26
chr17_17614010_17614161	0.68	RAI1	retinoic acid induced 1	28276	0.14
chr3_177234511_177234662	0.68	ENSG00000252028	.	13246	0.3
chr10_73019589_73019740	0.67	UNC5B-AS1	UNC5B antisense RNA 1	41679	0.12
chr3_52080953_52081104	0.66	DUSP7	dual specificity phosphatase 7	9153	0.12
chr5_168587659_168587810	0.66	ENSG00000207619	.	102964	0.07
chr11_61055093_61055244	0.65	VWCE	von Willebrand factor C and EGF domains	7728	0.13
chr11_57123702_57124132	0.64	ENSG00000266018	.	3279	0.12
chr17_55952277_55952762	0.64	CUEDC1	CUE domain containing 1	2488	0.26
chr11_65670447_65670677	0.63	FOSL1	FOS-like antigen 1	2518	0.12
chr16_56883616_56883799	0.61	ENSG00000207649	.	8723	0.14
chr8_38539787_38539938	0.61	TACC1	transforming, acidic coiled-coil containing protein 1	45842	0.14
chr10_111841442_111842330	0.61	ADD3	adducin 3 (gamma)	74164	0.09
chr19_48903661_48904050	0.61	GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	5723	0.11
chr1_117028094_117028245	0.61	ENSG00000200547	.	33011	0.13
chr20_36772405_36772603	0.60	TGM2	transglutaminase 2	21168	0.17
chr10_81200859_81201010	0.60	ZCCHC24	zinc finger, CCHC domain containing 24	3041	0.28
chr13_43819793_43820081	0.60	ENOX1	ecto-NOX disulfide-thiol exchanger 1	115276	0.07
chr22_46849624_46849775	0.60	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1	81492	0.08
chr7_48290426_48290608	0.60	ABCA13	ATP-binding cassette, sub-family A (ABC1), member 13	79460	0.11
chr8_99376791_99376994	0.60	KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	62358	0.11
chr1_17909315_17909466	0.59	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like	2342	0.4
chr3_182880353_182880504	0.59	LAMP3	lysosomal-associated membrane protein 3	242	0.94
chr3_8649116_8649267	0.59	LMCD1-AS1	LMCD1 antisense RNA 1 (head to head)	4395	0.22
chr17_74382503_74382654	0.58	SPHK1	sphingosine kinase 1	1205	0.31
chr6_14540959_14541110	0.58	ENSG00000206960	.	105732	0.08
chr11_10373135_10373286	0.58	AMPD3	adenosine monophosphate deaminase 3	33992	0.13
chr13_28902618_28902769	0.58	FLT1	fms-related tyrosine kinase 1	5923	0.29
chr17_17669783_17670067	0.58	RAI1-AS1	RAI1 antisense RNA 1	4210	0.15
chr19_46876400_46876551	0.58	AC007193.9		9951	0.12
chr6_128828631_128828782	0.57	RP1-86D1.4		2436	0.25
chr16_49734250_49734401	0.57	ENSG00000221134	.	21194	0.22
chr16_72961357_72961552	0.57	ENSG00000221799	.	57302	0.12
chr7_5452523_5452740	0.57	TNRC18	trinucleotide repeat containing 18	5606	0.15
chr15_80109103_80109367	0.56	ENSG00000252995	.	557	0.82
chr6_14743458_14743640	0.56	ENSG00000206960	.	96783	0.09
chr17_36667174_36667728	0.56	ARHGAP23	Rho GTPase activating protein 23	13416	0.16
chr1_43918298_43918577	0.56	HYI	hydroxypyruvate isomerase (putative)	686	0.48
chr10_72056262_72056676	0.56	NPFFR1	neuropeptide FF receptor 1	13037	0.21
chr7_93976913_93977064	0.55	COL1A2	collagen, type I, alpha 2	46885	0.18
chr2_218574918_218575069	0.55	DIRC3	disrupted in renal carcinoma 3	46285	0.18
chr2_239773492_239773709	0.55	TWIST2	twist family bHLH transcription factor 2	16927	0.24
chr14_75919638_75919789	0.55	JDP2	Jun dimerization protein 2	20876	0.17
chr21_44918501_44918652	0.55	SIK1	salt-inducible kinase 1	71568	0.11
chr15_67316146_67316685	0.54	SMAD3	SMAD family member 3	39686	0.2
chr7_90794057_90794258	0.54	FZD1	frizzled family receptor 1	99626	0.09
chr17_2310691_2310842	0.54	MNT	MAX network transcriptional repressor	6354	0.12
chr15_67457558_67457709	0.54	SMAD3	SMAD family member 3	724	0.72
chr17_25681100_25681558	0.54	WSB1	WD repeat and SOCS box containing 1	59957	0.11
chr1_201645041_201645675	0.54	RP11-25B7.1		2086	0.26
chr1_27057613_27057764	0.54	ARID1A	AT rich interactive domain 1A (SWI-like)	1817	0.28
chr6_46111105_46111256	0.53	ENPP4	ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)	13450	0.18
chr9_113309012_113309163	0.53	ENSG00000212254	.	7009	0.26
chr19_49004091_49004498	0.53	LMTK3	lemur tyrosine kinase 3	10767	0.1
chr16_70726438_70726684	0.53	VAC14	Vac14 homolog (S. cerevisiae)	2935	0.19
chr12_49663177_49663419	0.53	RP11-161H23.5		3791	0.13
chr20_5100313_5100464	0.52	PCNA	proliferating cell nuclear antigen	284	0.83
chr17_79393744_79394123	0.52	RP11-1055B8.7	BAH and coiled-coil domain-containing protein 1	11463	0.11
chr8_49676509_49676660	0.52	EFCAB1	EF-hand calcium binding domain 1	28714	0.25
chr19_52233260_52233541	0.52	HAS1	hyaluronan synthase 1	6153	0.11
chr1_68252004_68252155	0.52	ENSG00000238778	.	13743	0.21
chr12_76052830_76052981	0.51	ENSG00000251893	.	30179	0.2
chr14_75926083_75926288	0.51	JDP2	Jun dimerization protein 2	27348	0.16
chr21_47813743_47813894	0.51	PCNT	pericentrin	43136	0.11
chr15_58733197_58733348	0.51	LIPC	lipase, hepatic	9082	0.21
chr8_22598834_22598985	0.51	ENSG00000253125	.	6107	0.18
chr7_116331971_116332122	0.51	MET	met proto-oncogene	7093	0.26
chr2_95987573_95987724	0.50	KCNIP3	Kv channel interacting protein 3, calsenilin	11678	0.23
chr8_145734382_145734533	0.50	MFSD3	major facilitator superfamily domain containing 3	0	0.92
chr7_8149373_8149524	0.49	AC006042.6		4207	0.27
chr2_241861602_241861753	0.49	AC104809.3	Protein LOC728763	309	0.87
chr16_84844160_84844846	0.49	CRISPLD2	cysteine-rich secretory protein LCCL domain containing 2	9087	0.18
chr16_88366119_88366347	0.49	ZNF469	zinc finger protein 469	127646	0.05
chr1_201992311_201992462	0.49	RP11-510N19.5		11888	0.11
chr2_171381606_171381757	0.49	AC007277.3		118773	0.06
chr12_49580416_49580658	0.49	TUBA1A	tubulin, alpha 1a	110	0.95
chr5_14055268_14055419	0.49	TRIO	trio Rho guanine nucleotide exchange factor	88468	0.1
chr22_24870211_24870362	0.48	UPB1	ureidopropionase, beta	7080	0.16
chr16_57180947_57181162	0.48	FAM192A	family with sequence similarity 192, member A	26646	0.12
chr6_148271708_148271859	0.48	SASH1	SAM and SH3 domain containing 1	321657	0.01
chr3_54939961_54940112	0.48	CACNA2D3-AS1	CACNA2D3 antisense RNA 1	4754	0.29
chr7_18809339_18809490	0.48	ENSG00000222164	.	38488	0.21
chr17_54851727_54851878	0.47	C17orf67	chromosome 17 open reading frame 67	41448	0.14
chr11_73309592_73309967	0.47	FAM168A	family with sequence similarity 168, member A	545	0.79
chr1_231917552_231917705	0.47	ENSG00000222986	.	111247	0.06
chr11_133995520_133995672	0.47	NCAPD3	non-SMC condensin II complex, subunit D3	42771	0.13
chr12_112621415_112621566	0.47	HECTD4	HECT domain containing E3 ubiquitin protein ligase 4	6984	0.18
chr9_115940859_115941010	0.47	SLC31A2	solute carrier family 31 (copper transporter), member 2	27712	0.15
chr6_8180536_8180832	0.47	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	77873	0.11
chr1_17636370_17636667	0.46	PADI4	peptidyl arginine deiminase, type IV	1826	0.31
chr12_130646297_130646669	0.46	FZD10	frizzled family receptor 10	521	0.88
chr20_62089406_62089557	0.46	RP11-358D14.2		10077	0.12
chr4_186651858_186652115	0.46	SORBS2	sorbin and SH3 domain containing 2	9498	0.21
chr22_39688804_39689038	0.46	RP3-333H23.8		72	0.95
chr20_1783720_1783871	0.45	SIRPA	signal-regulatory protein alpha	91359	0.07
chr7_93539808_93539959	0.45	GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	3977	0.19
chr11_114248963_114249341	0.45	RP11-64D24.4		1615	0.32
chr8_97279888_97280058	0.45	PTDSS1	phosphatidylserine synthase 1	5832	0.17
chr3_42693962_42694141	0.45	ZBTB47	zinc finger and BTB domain containing 47	1125	0.31
chr5_102780433_102780701	0.45	NUDT12	nudix (nucleoside diphosphate linked moiety X)-type motif 12	117923	0.06
chr2_99528935_99529086	0.45	KIAA1211L	KIAA1211-like	4026	0.3
chr1_155223556_155224415	0.45	FAM189B	family with sequence similarity 189, member B	714	0.38
chr5_54280930_54281081	0.44	ESM1	endothelial cell-specific molecule 1	416	0.82
chr19_2529730_2529881	0.44	ENSG00000252962	.	26666	0.13
chr5_177963455_177963606	0.44	COL23A1	collagen, type XXIII, alpha 1	25709	0.2
chr7_101457741_101458764	0.44	CUX1	cut-like homeobox 1	707	0.73
chr12_125327332_125327720	0.44	SCARB1	scavenger receptor class B, member 1	2937	0.3
chr5_151054870_151055036	0.43	CTB-113P19.1		1553	0.32
chr2_217970592_217970881	0.43	ENSG00000251849	.	70485	0.12
chr4_16028808_16029222	0.43	ENSG00000251758	.	18605	0.2
chr1_17951607_17951758	0.43	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like	6833	0.29
chr15_45748380_45748570	0.43	RP11-519G16.3		2733	0.15
chr8_11373209_11373360	0.43	BLK	B lymphoid tyrosine kinase	21385	0.13
chr11_59524240_59524533	0.43	STX3	syntaxin 3	1461	0.29
chr16_70716878_70717029	0.43	MTSS1L	metastasis suppressor 1-like	3016	0.19
chr17_75417410_75417842	0.43	SEPT9	septin 9	1742	0.31
chr5_176914993_176915144	0.43	RP11-1334A24.6		6928	0.1
chrX_19621349_19621543	0.42	SH3KBP1	SH3-domain kinase binding protein 1	67034	0.13
chr12_93516624_93516849	0.42	RP11-511B23.2		16131	0.2
chr19_18571206_18571357	0.42	ELL	elongation factor RNA polymerase II	15462	0.09
chr17_2310928_2311079	0.42	MNT	MAX network transcriptional repressor	6591	0.12
chr22_36903062_36903213	0.42	FOXRED2	FAD-dependent oxidoreductase domain containing 2	11	0.97
chr5_1004113_1004264	0.42	ENSG00000221244	.	114	0.95
chr16_152002_152153	0.42	Z69720.2		11448	0.09
chr1_45279408_45279559	0.42	BTBD19	BTB (POZ) domain containing 19	5288	0.08
chr12_25959266_25959417	0.42	ENSG00000222950	.	26838	0.24
chr7_41926654_41927141	0.41	AC005027.3		181964	0.03
chr19_8017646_8018209	0.41	CTD-3193O13.14		6080	0.08
chr3_124826438_124826589	0.41	ENSG00000199327	.	11531	0.17
chr7_137621728_137621986	0.41	CREB3L2	cAMP responsive element binding protein 3-like 2	3221	0.27
chr2_28625085_28625236	0.41	RP11-373D23.2		5478	0.18
chr17_38643211_38643393	0.41	TNS4	tensin 4	8402	0.16
chr9_124650254_124650616	0.41	RP11-244O19.1		68704	0.12
chr19_6220741_6220892	0.41	RFX2	regulatory factor X, 2 (influences HLA class II expression)	21276	0.14
chr11_94523601_94523752	0.41	AMOTL1	angiomotin like 1	22139	0.21
chr9_96354377_96354528	0.41	PHF2	PHD finger protein 2	15543	0.19
chr20_2852821_2853294	0.41	PTPRA	protein tyrosine phosphatase, receptor type, A	1009	0.46
chr20_359199_359350	0.40	TRIB3	tribbles pseudokinase 3	1987	0.25
chr10_99332980_99333131	0.40	ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	519	0.68
chr3_194892357_194892562	0.40	XXYLT1	xyloside xylosyltransferase 1	3943	0.18
chr9_138749633_138749784	0.40	CAMSAP1	calmodulin regulated spectrin-associated protein 1	25035	0.18
chr19_9473586_9473877	0.39	ZNF177	zinc finger protein 177	24	0.97
chr12_49983022_49983173	0.39	ENSG00000199237	.	3790	0.15
chr22_36278822_36279066	0.39	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	42310	0.19
chr12_19728777_19728928	0.39	AEBP2	AE binding protein 2	75789	0.11
chr12_13025678_13025838	0.39	GPRC5A	G protein-coupled receptor, family C, group 5, member A	17958	0.14
chr10_73625407_73625558	0.39	PSAP	prosaposin	14356	0.19
chr1_112275365_112275766	0.39	FAM212B	family with sequence similarity 212, member B	6310	0.18
chr11_65075775_65076171	0.39	CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2	6316	0.13
chr12_15754427_15754578	0.39	PTPRO	protein tyrosine phosphatase, receptor type, O	20805	0.23
chr15_74277001_74277287	0.39	STOML1	stomatin (EPB72)-like 1	7031	0.16
chr18_33887353_33887504	0.39	FHOD3	formin homology 2 domain containing 3	9629	0.28
chr7_40611624_40611778	0.38	AC004988.1		25174	0.27
chr13_24782132_24782457	0.38	SPATA13	spermatogenesis associated 13	43538	0.13
chr14_76447358_76447593	0.38	TGFB3	transforming growth factor, beta 3	59	0.98
chr17_76993895_76994046	0.38	CANT1	calcium activated nucleotidase 1	11842	0.13
chr6_150246933_150247085	0.38	RAET1G	retinoic acid early transcript 1G	2752	0.18
chr20_60944733_60944974	0.38	LAMA5	laminin, alpha 5	2485	0.18
chr2_9777860_9778099	0.38	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta	6836	0.21
chr5_398631_398914	0.38	AHRR	aryl-hydrocarbon receptor repressor	22263	0.14
chrX_20085662_20085960	0.38	MAP7D2	MAP7 domain containing 2	10916	0.18
chr20_48450027_48450178	0.38	ENSG00000252123	.	5573	0.18
chr13_40105757_40105908	0.38	LHFP	lipoma HMGIC fusion partner	71476	0.11
chr22_30841104_30841316	0.37	MTFP1	mitochondrial fission process 1	19405	0.07
chr19_16177822_16178237	0.37	TPM4	tropomyosin 4	198	0.94
chr22_45933959_45934110	0.37	FBLN1	fibulin 1	19371	0.2
chr10_95226291_95226450	0.37	MYOF	myoferlin	15581	0.19
chr13_97959313_97959591	0.37	MBNL2	muscleblind-like splicing regulator 2	30994	0.21
chr19_46524126_46524277	0.37	ENSG00000211580	.	2011	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF143

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.4	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.4	GO:0019985	translesion synthesis(GO:0019985)
0.1	0.3	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	1.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.2	GO:0010193	response to ozone(GO:0010193)
0.1	0.3	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1	0.2	GO:0046084	adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1	0.2	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.1	0.2	GO:0018101	protein citrullination(GO:0018101)
0.1	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	0.2	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.2	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.2	GO:0071883	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1	0.3	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.1	0.2	GO:2000188	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.3	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.3	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.2	GO:0033604	negative regulation of catecholamine secretion(GO:0033604)
0.0	0.2	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0014832	urinary bladder smooth muscle contraction(GO:0014832)
0.0	0.1	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.1	GO:0033240	positive regulation of cellular amine metabolic process(GO:0033240)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.2	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.7	GO:0034333	adherens junction assembly(GO:0034333)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.4	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.1	GO:0035581	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.2	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.2	GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0	0.1	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.0	GO:0008615	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.2	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.1	GO:0060014	granulosa cell differentiation(GO:0060014)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.2	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.1	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.2	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0090505	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0	0.0	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.2	GO:1901072	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.2	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.1	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.6	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:2000846	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0010155	regulation of proton transport(GO:0010155)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0015858	nucleoside transport(GO:0015858)
0.0	0.1	GO:0060174	limb bud formation(GO:0060174)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0060058	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.4	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0	0.0	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.0	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0	0.1	GO:0034644	cellular response to UV(GO:0034644)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.0	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.3	GO:0019674	NAD metabolic process(GO:0019674)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0055012	ventricular cardiac muscle cell differentiation(GO:0055012)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.0	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.0	0.0	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:0070977	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0	0.0	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0044557	relaxation of smooth muscle(GO:0044557) negative regulation of smooth muscle contraction(GO:0045986) relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.2	GO:0007052	mitotic spindle organization(GO:0007052)
0.0	0.0	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.1	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.0	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.2	GO:0042462	photoreceptor cell development(GO:0042461) eye photoreceptor cell development(GO:0042462)
0.0	0.1	GO:0033598	mammary gland epithelial cell proliferation(GO:0033598)
0.0	0.0	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0006386	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.0	GO:0010659	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.0	GO:0045332	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.0	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0003161	cardiac conduction system development(GO:0003161)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.0	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.0	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.1	GO:0010718	positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0072194	kidney smooth muscle tissue development(GO:0072194)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.0	GO:1900121	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0	0.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.2	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.0	0.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.2	GO:0007030	Golgi organization(GO:0007030)
0.0	0.4	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.3	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.4	GO:0005663	DNA replication factor C complex(GO:0005663)
0.1	0.2	GO:0031262	Ndc80 complex(GO:0031262)
0.0	1.2	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0043256	laminin complex(GO:0043256)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.4	GO:0030315	T-tubule(GO:0030315)
0.0	0.2	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.4	GO:0071565	nBAF complex(GO:0071565)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.5	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.0	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.3	GO:0032982	myosin filament(GO:0032982)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.0	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.2	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.0	GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.0	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.0	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.1	0.5	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.3	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.4	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.1	0.2	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.2	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.2	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.1	0.2	GO:0045545	syndecan binding(GO:0045545)
0.1	0.2	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.2	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.2	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.2	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.4	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.3	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.5	GO:0043236	laminin binding(GO:0043236)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.0	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.2	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.5	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.0	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.2	GO:0022821	potassium ion antiporter activity(GO:0022821)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.9	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.2	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0016918	retinal binding(GO:0016918)
0.0	0.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.0	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.0	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.0	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.1	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.0	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.3	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.0	PID MYC PATHWAY	C-MYC pathway
0.0	0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.7	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.4	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.2	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.3	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.0	PID IFNG PATHWAY	IFN-gamma pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.5	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.5	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
1.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.4	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.2	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	REACTOME SIGNALING BY THE B CELL RECEPTOR BCR	Genes involved in Signaling by the B Cell Receptor (BCR)
0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1