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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ZNF143

Z-value: 1.65

Motif logo

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Transcription factors associated with ZNF143

Gene Symbol Gene ID Gene Info
ZNF143
ENSG00000166478.5 zinc finger protein 143

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_9511208_9511359ZNF143227610.1409380.791.1e-02Click!
chr11_9481615_9481873ZNF1431220.691450-0.791.1e-02Click!
chr11_9556875_9557026ZNF143229060.1385140.771.4e-02Click!
chr11_9510681_9510832ZNF143232880.1396710.713.4e-02Click!
chr11_9532170_9532321ZNF14317990.327001-0.665.5e-02Click!

Activity of the ZNF143 motif across conditions

Conditions sorted by the z-value of the ZNF143 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr15_41912974_41913725 1.46 MGA
 MGA, MAX dimerization protein
 385
 0.85
chr1_150510557_150510858 1.43 ADAMTSL4
 ADAMTS-like 4
 11177
 0.08
chr9_132236336_132236633 1.25 ENSG00000264298
 .
 4351
 0.26
chr8_37556598_37557288 1.17 ZNF703
 zinc finger protein 703
 3674
 0.16
chr8_49341467_49342503 1.03 ENSG00000252710
 .
 121395
 0.06
chr16_85424724_85424875 1.02 RP11-680G10.1
 Uncharacterized protein
 33730
 0.18
chr18_21464195_21464346 1.02 LAMA3
 laminin, alpha 3
 467
 0.84
chr1_8272810_8272977 1.00 ENSG00000200975
 .
 6236
 0.24
chr18_42179529_42179680 0.91 SETBP1
 SET binding protein 1
 80534
 0.12
chr16_88366428_88366870 0.89 ZNF469
 zinc finger protein 469
 127230
 0.05
chr10_104385999_104386279 0.88 TRIM8
 tripartite motif containing 8
 18114
 0.15
chr16_56884007_56884388 0.86 ENSG00000207649
 .
 8233
 0.14
chr21_17959428_17959579 0.85 ENSG00000207863
 .
 3054
 0.31
chr2_238804572_238804786 0.85 ENSG00000263723
 .
 26132
 0.17
chr2_43301822_43302026 0.83 ENSG00000207087
 .
 16708
 0.28
chr2_19340414_19340714 0.83 ENSG00000266738
 .
 207626
 0.03
chr1_203524952_203525250 0.83 OPTC
 opticin
 60003
 0.11
chr17_14821652_14821803 0.82 ENSG00000238806
 .
 319473
 0.01
chr17_36604180_36604649 0.80 ENSG00000260833
 .
 3518
 0.2
chr11_35551231_35551382 0.77 PAMR1
 peptidase domain containing associated with muscle regeneration 1
 542
 0.83
chr1_32038621_32038861 0.77 RP11-73M7.1
2433
 0.21
chr11_72500407_72500904 0.76 STARD10
 StAR-related lipid transfer (START) domain containing 10
 3643
 0.14
chr9_130817852_130818146 0.76 RP11-379C10.1
1642
 0.22
chr9_37966595_37966746 0.75 ENSG00000251745
 .
 29905
 0.19
chr1_17908500_17908722 0.73 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
 1563
 0.51
chr3_138581340_138581807 0.73 PIK3CB
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
 27793
 0.2
chr13_110161938_110162089 0.72 LINC00676
 long intergenic non-protein coding RNA 676
 218616
 0.02
chr21_37583097_37583248 0.72 ENSG00000265882
 .
 2964
 0.22
chr14_23316976_23317711 0.71 ENSG00000212335
 .
 4594
 0.09
chr17_9331018_9331169 0.70 AC087501.1
24421
 0.18
chr1_230379381_230379663 0.70 RP5-956O18.2
24707
 0.21
chr15_48919832_48919983 0.70 FBN1
 fibrillin 1
 18011
 0.26
chr17_17614010_17614161 0.68 RAI1
 retinoic acid induced 1
 28276
 0.14
chr3_177234511_177234662 0.68 ENSG00000252028
 .
 13246
 0.3
chr10_73019589_73019740 0.67 UNC5B-AS1
 UNC5B antisense RNA 1
 41679
 0.12
chr3_52080953_52081104 0.66 DUSP7
 dual specificity phosphatase 7
 9153
 0.12
chr5_168587659_168587810 0.66 ENSG00000207619
 .
 102964
 0.07
chr11_61055093_61055244 0.65 VWCE
 von Willebrand factor C and EGF domains
 7728
 0.13
chr11_57123702_57124132 0.64 ENSG00000266018
 .
 3279
 0.12
chr17_55952277_55952762 0.64 CUEDC1
 CUE domain containing 1
 2488
 0.26
chr11_65670447_65670677 0.63 FOSL1
 FOS-like antigen 1
 2518
 0.12
chr16_56883616_56883799 0.61 ENSG00000207649
 .
 8723
 0.14
chr8_38539787_38539938 0.61 TACC1
 transforming, acidic coiled-coil containing protein 1
 45842
 0.14
chr10_111841442_111842330 0.61 ADD3
 adducin 3 (gamma)
 74164
 0.09
chr19_48903661_48904050 0.61 GRIN2D
 glutamate receptor, ionotropic, N-methyl D-aspartate 2D
 5723
 0.11
chr1_117028094_117028245 0.61 ENSG00000200547
 .
 33011
 0.13
chr20_36772405_36772603 0.60 TGM2
 transglutaminase 2
 21168
 0.17
chr10_81200859_81201010 0.60 ZCCHC24
 zinc finger, CCHC domain containing 24
 3041
 0.28
chr13_43819793_43820081 0.60 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
 115276
 0.07
chr22_46849624_46849775 0.60 CELSR1
 cadherin, EGF LAG seven-pass G-type receptor 1
 81492
 0.08
chr7_48290426_48290608 0.60 ABCA13
 ATP-binding cassette, sub-family A (ABC1), member 13
 79460
 0.11
chr8_99376791_99376994 0.60 KCNS2
 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
 62358
 0.11
chr1_17909315_17909466 0.59 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
 2342
 0.4
chr3_182880353_182880504 0.59 LAMP3
 lysosomal-associated membrane protein 3
 242
 0.94
chr3_8649116_8649267 0.59 LMCD1-AS1
 LMCD1 antisense RNA 1 (head to head)
 4395
 0.22
chr17_74382503_74382654 0.58 SPHK1
 sphingosine kinase 1
 1205
 0.31
chr6_14540959_14541110 0.58 ENSG00000206960
 .
 105732
 0.08
chr11_10373135_10373286 0.58 AMPD3
 adenosine monophosphate deaminase 3
 33992
 0.13
chr13_28902618_28902769 0.58 FLT1
 fms-related tyrosine kinase 1
 5923
 0.29
chr17_17669783_17670067 0.58 RAI1-AS1
 RAI1 antisense RNA 1
 4210
 0.15
chr19_46876400_46876551 0.58 AC007193.9
9951
 0.12
chr6_128828631_128828782 0.57 RP1-86D1.4
2436
 0.25
chr16_49734250_49734401 0.57 ENSG00000221134
 .
 21194
 0.22
chr16_72961357_72961552 0.57 ENSG00000221799
 .
 57302
 0.12
chr7_5452523_5452740 0.57 TNRC18
 trinucleotide repeat containing 18
 5606
 0.15
chr15_80109103_80109367 0.56 ENSG00000252995
 .
 557
 0.82
chr6_14743458_14743640 0.56 ENSG00000206960
 .
 96783
 0.09
chr17_36667174_36667728 0.56 ARHGAP23
 Rho GTPase activating protein 23
 13416
 0.16
chr1_43918298_43918577 0.56 HYI
 hydroxypyruvate isomerase (putative)
 686
 0.48
chr10_72056262_72056676 0.56 NPFFR1
 neuropeptide FF receptor 1
 13037
 0.21
chr7_93976913_93977064 0.55 COL1A2
 collagen, type I, alpha 2
 46885
 0.18
chr2_218574918_218575069 0.55 DIRC3
 disrupted in renal carcinoma 3
 46285
 0.18
chr2_239773492_239773709 0.55 TWIST2
 twist family bHLH transcription factor 2
 16927
 0.24
chr14_75919638_75919789 0.55 JDP2
 Jun dimerization protein 2
 20876
 0.17
chr21_44918501_44918652 0.55 SIK1
 salt-inducible kinase 1
 71568
 0.11
chr15_67316146_67316685 0.54 SMAD3
 SMAD family member 3
 39686
 0.2
chr7_90794057_90794258 0.54 FZD1
 frizzled family receptor 1
 99626
 0.09
chr17_2310691_2310842 0.54 MNT
 MAX network transcriptional repressor
 6354
 0.12
chr15_67457558_67457709 0.54 SMAD3
 SMAD family member 3
 724
 0.72
chr17_25681100_25681558 0.54 WSB1
 WD repeat and SOCS box containing 1
 59957
 0.11
chr1_201645041_201645675 0.54 RP11-25B7.1
2086
 0.26
chr1_27057613_27057764 0.54 ARID1A
 AT rich interactive domain 1A (SWI-like)
 1817
 0.28
chr6_46111105_46111256 0.53 ENPP4
 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
 13450
 0.18
chr9_113309012_113309163 0.53 ENSG00000212254
 .
 7009
 0.26
chr19_49004091_49004498 0.53 LMTK3
 lemur tyrosine kinase 3
 10767
 0.1
chr16_70726438_70726684 0.53 VAC14
 Vac14 homolog (S. cerevisiae)
 2935
 0.19
chr12_49663177_49663419 0.53 RP11-161H23.5
3791
 0.13
chr20_5100313_5100464 0.52 PCNA
 proliferating cell nuclear antigen
 284
 0.83
chr17_79393744_79394123 0.52 RP11-1055B8.7
 BAH and coiled-coil domain-containing protein 1
 11463
 0.11
chr8_49676509_49676660 0.52 EFCAB1
 EF-hand calcium binding domain 1
 28714
 0.25
chr19_52233260_52233541 0.52 HAS1
 hyaluronan synthase 1
 6153
 0.11
chr1_68252004_68252155 0.52 ENSG00000238778
 .
 13743
 0.21
chr12_76052830_76052981 0.51 ENSG00000251893
 .
 30179
 0.2
chr14_75926083_75926288 0.51 JDP2
 Jun dimerization protein 2
 27348
 0.16
chr21_47813743_47813894 0.51 PCNT
 pericentrin
 43136
 0.11
chr15_58733197_58733348 0.51 LIPC
 lipase, hepatic
 9082
 0.21
chr8_22598834_22598985 0.51 ENSG00000253125
 .
 6107
 0.18
chr7_116331971_116332122 0.51 MET
 met proto-oncogene
 7093
 0.26
chr2_95987573_95987724 0.50 KCNIP3
 Kv channel interacting protein 3, calsenilin
 11678
 0.23
chr8_145734382_145734533 0.50 MFSD3
 major facilitator superfamily domain containing 3
 0
 0.92
chr7_8149373_8149524 0.49 AC006042.6
4207
 0.27
chr2_241861602_241861753 0.49 AC104809.3
 Protein LOC728763
 309
 0.87
chr16_84844160_84844846 0.49 CRISPLD2
 cysteine-rich secretory protein LCCL domain containing 2
 9087
 0.18
chr16_88366119_88366347 0.49 ZNF469
 zinc finger protein 469
 127646
 0.05
chr1_201992311_201992462 0.49 RP11-510N19.5
11888
 0.11
chr2_171381606_171381757 0.49 AC007277.3
118773
 0.06
chr12_49580416_49580658 0.49 TUBA1A
 tubulin, alpha 1a
 110
 0.95
chr5_14055268_14055419 0.49 TRIO
 trio Rho guanine nucleotide exchange factor
 88468
 0.1
chr22_24870211_24870362 0.48 UPB1
 ureidopropionase, beta
 7080
 0.16
chr16_57180947_57181162 0.48 FAM192A
 family with sequence similarity 192, member A
 26646
 0.12
chr6_148271708_148271859 0.48 SASH1
 SAM and SH3 domain containing 1
 321657
 0.01
chr3_54939961_54940112 0.48 CACNA2D3-AS1
 CACNA2D3 antisense RNA 1
 4754
 0.29
chr7_18809339_18809490 0.48 ENSG00000222164
 .
 38488
 0.21
chr17_54851727_54851878 0.47 C17orf67
 chromosome 17 open reading frame 67
 41448
 0.14
chr11_73309592_73309967 0.47 FAM168A
 family with sequence similarity 168, member A
 545
 0.79
chr1_231917552_231917705 0.47 ENSG00000222986
 .
 111247
 0.06
chr11_133995520_133995672 0.47 NCAPD3
 non-SMC condensin II complex, subunit D3
 42771
 0.13
chr12_112621415_112621566 0.47 HECTD4
 HECT domain containing E3 ubiquitin protein ligase 4
 6984
 0.18
chr9_115940859_115941010 0.47 SLC31A2
 solute carrier family 31 (copper transporter), member 2
 27712
 0.15
chr6_8180536_8180832 0.47 EEF1E1
 eukaryotic translation elongation factor 1 epsilon 1
 77873
 0.11
chr1_17636370_17636667 0.46 PADI4
 peptidyl arginine deiminase, type IV
 1826
 0.31
chr12_130646297_130646669 0.46 FZD10
 frizzled family receptor 10
 521
 0.88
chr20_62089406_62089557 0.46 RP11-358D14.2
10077
 0.12
chr4_186651858_186652115 0.46 SORBS2
 sorbin and SH3 domain containing 2
 9498
 0.21
chr22_39688804_39689038 0.46 RP3-333H23.8
72
 0.95
chr20_1783720_1783871 0.45 SIRPA
 signal-regulatory protein alpha
 91359
 0.07
chr7_93539808_93539959 0.45 GNGT1
 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
 3977
 0.19
chr11_114248963_114249341 0.45 RP11-64D24.4
1615
 0.32
chr8_97279888_97280058 0.45 PTDSS1
 phosphatidylserine synthase 1
 5832
 0.17
chr3_42693962_42694141 0.45 ZBTB47
 zinc finger and BTB domain containing 47
 1125
 0.31
chr5_102780433_102780701 0.45 NUDT12
 nudix (nucleoside diphosphate linked moiety X)-type motif 12
 117923
 0.06
chr2_99528935_99529086 0.45 KIAA1211L
 KIAA1211-like
 4026
 0.3
chr1_155223556_155224415 0.45 FAM189B
 family with sequence similarity 189, member B
 714
 0.38
chr5_54280930_54281081 0.44 ESM1
 endothelial cell-specific molecule 1
 416
 0.82
chr19_2529730_2529881 0.44 ENSG00000252962
 .
 26666
 0.13
chr5_177963455_177963606 0.44 COL23A1
 collagen, type XXIII, alpha 1
 25709
 0.2
chr7_101457741_101458764 0.44 CUX1
 cut-like homeobox 1
 707
 0.73
chr12_125327332_125327720 0.44 SCARB1
 scavenger receptor class B, member 1
 2937
 0.3
chr5_151054870_151055036 0.43 CTB-113P19.1
1553
 0.32
chr2_217970592_217970881 0.43 ENSG00000251849
 .
 70485
 0.12
chr4_16028808_16029222 0.43 ENSG00000251758
 .
 18605
 0.2
chr1_17951607_17951758 0.43 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
 6833
 0.29
chr15_45748380_45748570 0.43 RP11-519G16.3
2733
 0.15
chr8_11373209_11373360 0.43 BLK
 B lymphoid tyrosine kinase
 21385
 0.13
chr11_59524240_59524533 0.43 STX3
 syntaxin 3
 1461
 0.29
chr16_70716878_70717029 0.43 MTSS1L
 metastasis suppressor 1-like
 3016
 0.19
chr17_75417410_75417842 0.43 SEPT9
 septin 9
 1742
 0.31
chr5_176914993_176915144 0.43 RP11-1334A24.6
6928
 0.1
chrX_19621349_19621543 0.42 SH3KBP1
 SH3-domain kinase binding protein 1
 67034
 0.13
chr12_93516624_93516849 0.42 RP11-511B23.2
16131
 0.2
chr19_18571206_18571357 0.42 ELL
 elongation factor RNA polymerase II
 15462
 0.09
chr17_2310928_2311079 0.42 MNT
 MAX network transcriptional repressor
 6591
 0.12
chr22_36903062_36903213 0.42 FOXRED2
 FAD-dependent oxidoreductase domain containing 2
 11
 0.97
chr5_1004113_1004264 0.42 ENSG00000221244
 .
 114
 0.95
chr16_152002_152153 0.42 Z69720.2
11448
 0.09
chr1_45279408_45279559 0.42 BTBD19
 BTB (POZ) domain containing 19
 5288
 0.08
chr12_25959266_25959417 0.42 ENSG00000222950
 .
 26838
 0.24
chr7_41926654_41927141 0.41 AC005027.3
181964
 0.03
chr19_8017646_8018209 0.41 CTD-3193O13.14
6080
 0.08
chr3_124826438_124826589 0.41 ENSG00000199327
 .
 11531
 0.17
chr7_137621728_137621986 0.41 CREB3L2
 cAMP responsive element binding protein 3-like 2
 3221
 0.27
chr2_28625085_28625236 0.41 RP11-373D23.2
5478
 0.18
chr17_38643211_38643393 0.41 TNS4
 tensin 4
 8402
 0.16
chr9_124650254_124650616 0.41 RP11-244O19.1
68704
 0.12
chr19_6220741_6220892 0.41 RFX2
 regulatory factor X, 2 (influences HLA class II expression)
 21276
 0.14
chr11_94523601_94523752 0.41 AMOTL1
 angiomotin like 1
 22139
 0.21
chr9_96354377_96354528 0.41 PHF2
 PHD finger protein 2
 15543
 0.19
chr20_2852821_2853294 0.41 PTPRA
 protein tyrosine phosphatase, receptor type, A
 1009
 0.46
chr20_359199_359350 0.40 TRIB3
 tribbles pseudokinase 3
 1987
 0.25
chr10_99332980_99333131 0.40 ANKRD2
 ankyrin repeat domain 2 (stretch responsive muscle)
 519
 0.68
chr3_194892357_194892562 0.40 XXYLT1
 xyloside xylosyltransferase 1
 3943
 0.18
chr9_138749633_138749784 0.40 CAMSAP1
 calmodulin regulated spectrin-associated protein 1
 25035
 0.18
chr19_9473586_9473877 0.39 ZNF177
 zinc finger protein 177
 24
 0.97
chr12_49983022_49983173 0.39 ENSG00000199237
 .
 3790
 0.15
chr22_36278822_36279066 0.39 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 42310
 0.19
chr12_19728777_19728928 0.39 AEBP2
 AE binding protein 2
 75789
 0.11
chr12_13025678_13025838 0.39 GPRC5A
 G protein-coupled receptor, family C, group 5, member A
 17958
 0.14
chr10_73625407_73625558 0.39 PSAP
 prosaposin
 14356
 0.19
chr1_112275365_112275766 0.39 FAM212B
 family with sequence similarity 212, member B
 6310
 0.18
chr11_65075775_65076171 0.39 CDC42EP2
 CDC42 effector protein (Rho GTPase binding) 2
 6316
 0.13
chr12_15754427_15754578 0.39 PTPRO
 protein tyrosine phosphatase, receptor type, O
 20805
 0.23
chr15_74277001_74277287 0.39 STOML1
 stomatin (EPB72)-like 1
 7031
 0.16
chr18_33887353_33887504 0.39 FHOD3
 formin homology 2 domain containing 3
 9629
 0.28
chr7_40611624_40611778 0.38 AC004988.1
25174
 0.27
chr13_24782132_24782457 0.38 SPATA13
 spermatogenesis associated 13
 43538
 0.13
chr14_76447358_76447593 0.38 TGFB3
 transforming growth factor, beta 3
 59
 0.98
chr17_76993895_76994046 0.38 CANT1
 calcium activated nucleotidase 1
 11842
 0.13
chr6_150246933_150247085 0.38 RAET1G
 retinoic acid early transcript 1G
 2752
 0.18
chr20_60944733_60944974 0.38 LAMA5
 laminin, alpha 5
 2485
 0.18
chr2_9777860_9778099 0.38 YWHAQ
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
 6836
 0.21
chr5_398631_398914 0.38 AHRR
 aryl-hydrocarbon receptor repressor
 22263
 0.14
chrX_20085662_20085960 0.38 MAP7D2
 MAP7 domain containing 2
 10916
 0.18
chr20_48450027_48450178 0.38 ENSG00000252123
 .
 5573
 0.18
chr13_40105757_40105908 0.38 LHFP
 lipoma HMGIC fusion partner
 71476
 0.11
chr22_30841104_30841316 0.37 MTFP1
 mitochondrial fission process 1
 19405
 0.07
chr19_16177822_16178237 0.37 TPM4
 tropomyosin 4
 198
 0.94
chr22_45933959_45934110 0.37 FBLN1
 fibulin 1
 19371
 0.2
chr10_95226291_95226450 0.37 MYOF
 myoferlin
 15581
 0.19
chr13_97959313_97959591 0.37 MBNL2
 muscleblind-like splicing regulator 2
 30994
 0.21
chr19_46524126_46524277 0.37 ENSG00000211580
 .
 2011
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF143

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.4 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.4 GO:0019985 translesion synthesis(GO:0019985)
0.1 0.3 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.1 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:0010193 response to ozone(GO:0010193)
0.1 0.3 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.2 GO:0046084 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.1 0.2 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.1 0.2 GO:0018101 protein citrullination(GO:0018101)
0.1 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.2 GO:0071883 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.3 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277)
0.1 0.2 GO:2000188 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.3 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.3 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.2 GO:0033604 negative regulation of catecholamine secretion(GO:0033604)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.0 0.1 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.1 GO:0033240 positive regulation of cellular amine metabolic process(GO:0033240)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.2 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.7 GO:0034333 adherens junction assembly(GO:0034333)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.4 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0060014 granulosa cell differentiation(GO:0060014)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0090505 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0 0.0 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.0 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.2 GO:1901072 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.6 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:2000846 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0010155 regulation of proton transport(GO:0010155)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0060058 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.4 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433) ERAD pathway(GO:0036503)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0003228 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.1 GO:0034644 cellular response to UV(GO:0034644)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.0 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.3 GO:0019674 NAD metabolic process(GO:0019674)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0070977 organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0 0.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0044557 relaxation of smooth muscle(GO:0044557) negative regulation of smooth muscle contraction(GO:0045986) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 0.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.0 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0042462 photoreceptor cell development(GO:0042461) eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0033598 mammary gland epithelial cell proliferation(GO:0033598)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.0 GO:0010659 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.0 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.0 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.0 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.0 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.0 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.0 GO:1900121 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.2 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
0.0 0.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.4 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 1.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.1 0.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.3 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.1 0.2 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.0 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0019959 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0016918 retinal binding(GO:0016918)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.0 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.0 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.0 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.0 GO:0002054 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.0 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.0 PID IFNG PATHWAY IFN-gamma pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.3 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME SIGNALING BY THE B CELL RECEPTOR BCR Genes involved in Signaling by the B Cell Receptor (BCR)
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.0 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1