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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZNF232

Z-value: 1.13

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Transcription factors associated with ZNF232

Gene Symbol	Gene ID	Gene Info
ZNF232 Ensembl NCBI GeneCards UniProt	ENSG00000167840.9	ZNF232

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ZNF232	chr17_5014893_5015044	168	0.531362	-0.84	4.3e-03	Click!
ZNF232	chr17_5025884_5026035	438	0.711549	-0.46	2.2e-01	Click!
ZNF232	chr17_5028739_5028890	2417	0.161305	-0.38	3.1e-01	Click!
ZNF232	chr17_5025598_5025749	724	0.508643	-0.38	3.2e-01	Click!
ZNF232	chr17_5026950_5027101	628	0.568930	-0.31	4.2e-01	Click!

Activity of the ZNF232 motif across conditions

Conditions sorted by the z-value of the ZNF232 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_108557025_108557176	0.76	TRAT1	T cell receptor associated transmembrane adaptor 1	15481	0.25
chr3_38071955_38072561	0.48	PLCD1	phospholipase C, delta 1	1005	0.45
chr10_33422454_33423119	0.46	ENSG00000263576	.	35222	0.17
chr13_94982893_94983044	0.44	ENSG00000212057	.	134676	0.05
chr12_124145145_124145296	0.39	TCTN2	tectonic family member 2	10440	0.13
chr10_31631628_31631809	0.39	RP11-192P3.5		21219	0.17
chr3_4864499_4864721	0.38	ENSG00000239126	.	55776	0.13
chr18_67557274_67557425	0.37	CD226	CD226 molecule	57306	0.16
chr6_128068941_128069092	0.37	THEMIS	thymocyte selection associated	153087	0.04
chr4_186133064_186133215	0.36	SNX25	sorting nexin 25	1906	0.3
chr6_139483644_139483926	0.36	HECA	headcase homolog (Drosophila)	27536	0.2
chr2_69815178_69815329	0.36	AAK1	AP2 associated kinase 1	55533	0.11
chr13_98113590_98113741	0.36	RAP2A	RAP2A, member of RAS oncogene family	27189	0.24
chr1_90077786_90078098	0.36	RP11-413E1.4		17342	0.16
chr1_121293995_121294146	0.35	FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)	358133	0.01
chr14_64340904_64341076	0.35	SYNE2	spectrin repeat containing, nuclear envelope 2	21258	0.2
chr5_66456559_66456909	0.35	MAST4	microtubule associated serine/threonine kinase family member 4	18472	0.24
chr3_150167839_150167990	0.34	TSC22D2	TSC22 domain family, member 2	39118	0.18
chr7_28164005_28164156	0.34	ENSG00000206623	.	6242	0.26
chr22_20909677_20910043	0.34	MED15	mediator complex subunit 15	4283	0.17
chr13_50830244_50830433	0.34	ENSG00000221198	.	107035	0.07
chr9_71991121_71991272	0.34	FAM189A2	family with sequence similarity 189, member A2	5014	0.31
chr8_37097408_37097594	0.33	RP11-150O12.6		277038	0.01
chr1_194022845_194023072	0.33	ENSG00000252241	.	321884	0.01
chr10_33225735_33225886	0.33	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	631	0.82
chr8_67443611_67443762	0.33	ENSG00000206949	.	30140	0.15
chr13_74899245_74899396	0.33	ENSG00000206617	.	35969	0.21
chr3_66330811_66331009	0.32	ENSG00000206759	.	12734	0.22
chr10_90763076_90763284	0.32	ACTA2	actin, alpha 2, smooth muscle, aorta	12033	0.14
chr2_219089063_219089333	0.31	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	7265	0.12
chr6_112121057_112121208	0.31	FYN	FYN oncogene related to SRC, FGR, YES	1506	0.54
chr2_106459836_106459987	0.31	NCK2	NCK adaptor protein 2	8293	0.24
chr12_20657108_20657259	0.31	RP11-284H19.1		133987	0.05
chr11_104786300_104786451	0.31	RP11-693N9.2		5733	0.21
chr10_33315822_33316332	0.31	ENSG00000265319	.	7775	0.23
chr2_26048696_26048925	0.31	ASXL2	additional sex combs like 2 (Drosophila)	45632	0.16
chr6_161498090_161498241	0.31	MAP3K4	mitogen-activated protein kinase kinase kinase 4	54939	0.14
chr22_23132033_23132342	0.30	ENSG00000207833	.	2790	0.07
chr1_78143107_78143258	0.30	ZZZ3	zinc finger, ZZ-type containing 3	5161	0.21
chr2_205736509_205736732	0.30	PARD3B	par-3 family cell polarity regulator beta	325897	0.01
chr2_106707234_106707385	0.30	C2orf40	chromosome 2 open reading frame 40	25053	0.21
chr3_43079553_43079704	0.29	FAM198A	family with sequence similarity 198, member A	58588	0.1
chr15_60684276_60684517	0.29	ANXA2	annexin A2	900	0.69
chr6_143203048_143203338	0.29	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	45009	0.18
chr17_47736485_47736636	0.29	SPOP	speckle-type POZ protein	12568	0.15
chr17_13971675_13971896	0.29	ENSG00000236088	.	990	0.42
chr18_43737463_43737614	0.29	C18orf25	chromosome 18 open reading frame 25	15981	0.17
chr5_141485413_141485564	0.29	NDFIP1	Nedd4 family interacting protein 1	2582	0.34
chr3_124722968_124723119	0.28	HEG1	heart development protein with EGF-like domains 1	2179	0.34
chr12_96598172_96598568	0.28	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	9978	0.2
chr12_47003400_47003570	0.28	SLC38A4	solute carrier family 38, member 4	159602	0.04
chr12_4401971_4402452	0.27	CCND2-AS1	CCND2 antisense RNA 1	16861	0.15
chr3_109619904_109620055	0.27	ENSG00000265956	.	298304	0.01
chr5_49698412_49698563	0.27	EMB	embigin	26074	0.28
chr6_158182790_158182947	0.27	SNX9	sorting nexin 9	61428	0.12
chr7_114597355_114597535	0.27	MDFIC	MyoD family inhibitor domain containing	23521	0.28
chr7_95130919_95131189	0.27	ASB4	ankyrin repeat and SOCS box containing 4	15841	0.18
chr2_55125265_55125416	0.27	ENSG00000252507	.	47914	0.15
chr7_6292541_6292692	0.27	CYTH3	cytohesin 3	19659	0.16
chr20_3137233_3137451	0.26	UBOX5	U-box domain containing 5	3180	0.15
chr4_109513219_109513370	0.26	ENSG00000266046	.	14998	0.2
chr3_45666862_45667013	0.26	LIMD1	LIM domains containing 1	30586	0.15
chr3_160159792_160159943	0.26	TRIM59	tripartite motif containing 59	6858	0.15
chrX_10076834_10077577	0.26	WWC3	WWC family member 3	45706	0.12
chr18_7963851_7964002	0.25	PTPRM	protein tyrosine phosphatase, receptor type, M	16974	0.22
chr1_40914947_40915118	0.25	ZFP69B	ZFP69 zinc finger protein B	747	0.56
chr6_16432796_16433123	0.25	ENSG00000265642	.	4205	0.35
chr8_125630679_125630830	0.25	RP11-532M24.1		38882	0.15
chr7_15502538_15502689	0.25	AGMO	alkylglycerol monooxygenase	96766	0.09
chr11_64640724_64641020	0.25	EHD1	EH-domain containing 1	2266	0.16
chr6_136200607_136200783	0.25	PDE7B	phosphodiesterase 7B	27861	0.2
chrX_46472704_46472855	0.24	CHST7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7	39560	0.17
chr3_55639839_55639990	0.24	WNT5A	wingless-type MMTV integration site family, member 5A	115941	0.07
chr2_12410968_12411119	0.24	ENSG00000264089	.	71787	0.13
chr11_96006440_96006591	0.24	ENSG00000266192	.	68087	0.11
chr1_222594825_222595030	0.24	ENSG00000222399	.	82150	0.1
chr10_27514870_27515021	0.24	ENSG00000251839	.	6300	0.14
chr5_80294021_80294254	0.24	CTC-459I6.1		37411	0.17
chr8_69645584_69645735	0.23	ENSG00000239184	.	37781	0.22
chr2_213996401_213996552	0.23	IKZF2	IKAROS family zinc finger 2 (Helios)	16877	0.28
chr2_239347338_239347489	0.23	AC016999.2		11043	0.17
chr10_15183836_15183987	0.23	NMT2	N-myristoyltransferase 2	18213	0.17
chr6_75657197_75657348	0.23	COL12A1	collagen, type XII, alpha 1	171502	0.03
chr4_80918707_80918911	0.23	ANTXR2	anthrax toxin receptor 2	74908	0.12
chr13_98573793_98573944	0.23	IPO5	importin 5	32044	0.2
chr9_4689321_4689472	0.23	CDC37L1	cell division cycle 37-like 1	9830	0.17
chr6_144880670_144880834	0.23	UTRN	utrophin	23594	0.28
chr15_93523585_93523736	0.23	CHD2	chromodomain helicase DNA binding protein 2	8547	0.26
chr6_112063218_112063369	0.23	FYN	FYN oncogene related to SRC, FGR, YES	17024	0.24
chr12_51702385_51702551	0.23	BIN2	bridging integrator 2	15431	0.14
chr14_99726600_99726784	0.23	AL109767.1		2593	0.31
chr6_169891020_169891171	0.23	WDR27	WD repeat domain 27	169693	0.03
chr15_78443266_78443417	0.23	IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	1608	0.31
chr4_38686540_38686749	0.23	RP11-617D20.1		20140	0.15
chr13_22025148_22025299	0.22	ZDHHC20	zinc finger, DHHC-type containing 20	8191	0.22
chr2_169290019_169290449	0.22	ENSG00000239230	.	7481	0.21
chr2_128120808_128120959	0.22	MAP3K2	mitogen-activated protein kinase kinase kinase 2	20078	0.16
chrY_2720348_2720499	0.22	RPS4Y1	ribosomal protein S4, Y-linked 1	10462	0.24
chr1_29272903_29273060	0.22	EPB41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	31890	0.15
chr7_114595751_114595902	0.22	MDFIC	MyoD family inhibitor domain containing	21902	0.28
chr10_131741460_131741611	0.22	EBF3	early B-cell factor 3	20570	0.27
chr15_52951493_52951915	0.22	FAM214A	family with sequence similarity 214, member A	7457	0.21
chr15_77749022_77749295	0.22	HMG20A	high mobility group 20A	1401	0.51
chr1_24021474_24021706	0.22	RPL11	ribosomal protein L11	2491	0.23
chr3_108323323_108323612	0.22	DZIP3	DAZ interacting zinc finger protein 3	1769	0.36
chr3_190099541_190099692	0.22	CLDN16	claudin 16	6045	0.26
chr1_117914498_117914649	0.22	MAN1A2	mannosidase, alpha, class 1A, member 2	4502	0.33
chr2_182089447_182089783	0.22	ENSG00000266705	.	80764	0.11
chr10_91393117_91393268	0.22	PANK1	pantothenate kinase 1	10439	0.18
chr9_74375290_74375441	0.22	TMEM2	transmembrane protein 2	7937	0.3
chr11_61311867_61312018	0.22	LRRC10B	leucine rich repeat containing 10B	35670	0.11
chr18_46464398_46464549	0.21	SMAD7	SMAD family member 7	10402	0.25
chr1_46281591_46281742	0.21	MAST2	microtubule associated serine/threonine kinase 2	12381	0.22
chr22_22121001_22121154	0.21	ENSG00000200985	.	25646	0.12
chr3_57547653_57547804	0.21	PDE12	phosphodiesterase 12	5724	0.12
chr3_71407403_71407554	0.21	FOXP1	forkhead box P1	53567	0.15
chr8_129588676_129588964	0.21	ENSG00000221351	.	243220	0.02
chr1_236697521_236697902	0.21	RP11-385F5.5		2293	0.24
chr2_203533655_203533879	0.21	FAM117B	family with sequence similarity 117, member B	33856	0.22
chr2_23509060_23509211	0.21	KLHL29	kelch-like family member 29	98953	0.09
chr2_12850330_12850505	0.21	TRIB2	tribbles pseudokinase 2	6598	0.28
chr20_55039592_55039752	0.21	RTFDC1	replication termination factor 2 domain containing 1	3975	0.15
chr1_180332594_180332745	0.21	ENSG00000265435	.	74856	0.09
chr10_31549661_31549812	0.21	ENSG00000252479	.	1208	0.55
chr12_111889383_111889585	0.21	ATXN2	ataxin 2	4432	0.21
chr8_22406945_22407789	0.20	SORBS3	sorbin and SH3 domain containing 3	1841	0.21
chr15_38965016_38965639	0.20	C15orf53	chromosome 15 open reading frame 53	23472	0.24
chr1_167480391_167480600	0.20	CD247	CD247 molecule	7280	0.21
chr12_107764032_107764308	0.20	ENSG00000200897	.	4354	0.29
chr13_113838414_113838565	0.20	RP11-98F14.11		18992	0.11
chr1_145432739_145432969	0.20	TXNIP	thioredoxin interacting protein	5615	0.13
chr3_11644429_11644663	0.20	VGLL4	vestigial like 4 (Drosophila)	1509	0.4
chrX_99902890_99903180	0.20	SRPX2	sushi-repeat containing protein, X-linked 2	3820	0.21
chr1_236579990_236580147	0.20	EDARADD	EDAR-associated death domain	21352	0.21
chr2_40325984_40326135	0.20	SLC8A1-AS1	SLC8A1 antisense RNA 1	5990	0.34
chr15_60715225_60715376	0.20	ANXA2	annexin A2	20218	0.21
chr16_84793876_84794027	0.20	USP10	ubiquitin specific peptidase 10	7920	0.22
chr2_213980870_213981021	0.20	IKZF2	IKAROS family zinc finger 2 (Helios)	32408	0.23
chr7_155440870_155441096	0.20	RBM33	RNA binding motif protein 33	3587	0.25
chr6_106541569_106541720	0.20	PRDM1	PR domain containing 1, with ZNF domain	4837	0.25
chr7_115302535_115302686	0.20	ENSG00000202377	.	81114	0.11
chr7_75111983_75112134	0.20	POM121C	POM121 transmembrane nucleoporin C	1547	0.29
chr3_158486550_158486701	0.20	RP11-379F4.8		13711	0.14
chr2_43793678_43793972	0.20	THADA	thyroid adenoma associated	3829	0.29
chr2_42526156_42526376	0.20	EML4	echinoderm microtubule associated protein like 4	2127	0.4
chrX_46308049_46308200	0.20	KRBOX4	KRAB box domain containing 4	456	0.88
chr22_40571602_40571800	0.20	TNRC6B	trinucleotide repeat containing 6B	2228	0.4
chr5_180243660_180244135	0.20	MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	1317	0.41
chr8_23619073_23619616	0.20	ENSG00000216123	.	6814	0.19
chr2_11480133_11480284	0.19	ROCK2	Rho-associated, coiled-coil containing protein kinase 2	4503	0.28
chr18_2967412_2967563	0.19	RP11-737O24.1		471	0.77
chr20_62894793_62894944	0.19	PCMTD2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2	1997	0.4
chr1_33122442_33122593	0.19	RBBP4	retinoblastoma binding protein 4	5429	0.15
chr2_169090927_169091234	0.19	STK39	serine threonine kinase 39	13571	0.29
chr16_28567039_28567190	0.19	CCDC101	coiled-coil domain containing 101	1867	0.24
chr12_66229210_66229361	0.19	HMGA2	high mobility group AT-hook 2	10382	0.2
chr2_239869911_239870176	0.19	ENSG00000211566	.	24663	0.17
chr5_56099308_56099459	0.19	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	12018	0.2
chr6_5520923_5521080	0.19	RP1-232P20.1		62693	0.14
chr15_36654222_36654373	0.19	C15orf41	chromosome 15 open reading frame 41	217515	0.02
chr19_12400747_12400928	0.19	ZNF44	zinc finger protein 44	4791	0.18
chrX_152849336_152849542	0.19	FAM58A	family with sequence similarity 58, member A	12025	0.13
chr13_74475259_74475410	0.19	KLF12	Kruppel-like factor 12	93852	0.1
chr10_121028118_121028299	0.19	ENSG00000242853	.	55839	0.09
chr15_52966509_52966798	0.19	FAM214A	family with sequence similarity 214, member A	3765	0.26
chr12_66700071_66700537	0.19	HELB	helicase (DNA) B	3979	0.2
chr2_102413944_102414095	0.19	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	293	0.94
chr17_37961333_37961484	0.19	IKZF3	IKAROS family zinc finger 3 (Aiolos)	26930	0.12
chr2_179971991_179972202	0.19	ENSG00000238339	.	18268	0.23
chr1_235418994_235419145	0.19	ARID4B	AT rich interactive domain 4B (RBP1-like)	41838	0.13
chr11_33290652_33290913	0.19	HIPK3	homeodomain interacting protein kinase 3	10905	0.22
chr3_20147969_20148120	0.19	ENSG00000266745	.	31013	0.16
chr8_69921640_69921791	0.18	ENSG00000238808	.	101094	0.09
chr10_70751231_70751471	0.18	KIAA1279	KIAA1279	2864	0.23
chr1_35652154_35652385	0.18	SFPQ	splicing factor proline/glutamine-rich	6480	0.19
chr5_55984183_55984556	0.18	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	82310	0.09
chr16_64230317_64230468	0.18	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	863189	0.0
chr11_73686038_73686668	0.18	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	1698	0.28
chr3_45963092_45963243	0.18	LZTFL1	leucine zipper transcription factor-like 1	5633	0.16
chr2_42404220_42404371	0.18	AC083949.1		6854	0.23
chr1_193152188_193152339	0.18	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	3521	0.25
chr3_48004374_48004525	0.18	ENSG00000199591	.	31045	0.16
chr7_130629524_130629906	0.18	LINC-PINT	long intergenic non-protein coding RNA, p53 induced transcript	39153	0.18
chr17_53847338_53847489	0.18	PCTP	phosphatidylcholine transfer protein	3684	0.32
chr13_40894745_40894896	0.18	ENSG00000252812	.	86757	0.09
chr1_31481065_31481216	0.18	PUM1	pumilio RNA-binding family member 1	13189	0.19
chr2_55757616_55757885	0.18	CCDC104	coiled-coil domain containing 104	10883	0.15
chr11_93468268_93468502	0.18	ENSG00000210825	.	17	0.89
chr3_114817466_114817617	0.18	ZBTB20	zinc finger and BTB domain containing 20	27319	0.27
chr14_72231747_72231898	0.18	SIPA1L1	signal-induced proliferation-associated 1 like 1	146349	0.04
chr3_118668683_118668834	0.18	IGSF11-AS1	IGSF11 antisense RNA 1	6838	0.28
chr3_176900690_176900841	0.18	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	13446	0.24
chr1_36003036_36003243	0.18	KIAA0319L	KIAA0319-like	17449	0.14
chr16_67323885_67324036	0.18	PLEKHG4	pleckstrin homology domain containing, family G (with RhoGef domain) member 4	2157	0.15
chr10_89298476_89298627	0.18	ENSG00000222192	.	24392	0.19
chr21_17656676_17656827	0.18	ENSG00000201025	.	338	0.94
chr3_66330359_66330510	0.18	ENSG00000206759	.	13210	0.22
chr5_77015099_77015250	0.18	TBCA	tubulin folding cofactor A	4032	0.32
chr4_186760718_186760869	0.18	SORBS2	sorbin and SH3 domain containing 2	26515	0.21
chr14_58759101_58759259	0.18	ENSG00000252782	.	74	0.95

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF232

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.4	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0060081	membrane hyperpolarization(GO:0060081)
0.0	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.4	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.0	GO:0002870	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.2	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.1	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.0	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.0	GO:0090266	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.0	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.0	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.0	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0002860	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.0	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	GO:0070552	BRISC complex(GO:0070552)
0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.4	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	GO:0072487	MSL complex(GO:0072487)
0.0	GO:0071942	XPC complex(GO:0071942)
0.1	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	GO:0042629	mast cell granule(GO:0042629)
0.1	GO:0016342	catenin complex(GO:0016342)
0.1	GO:0008091	spectrin(GO:0008091)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.0	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.0	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.0	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.0	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.0	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.0	GO:0045294	alpha-catenin binding(GO:0045294)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.8	PID REELIN PATHWAY	Reelin signaling pathway
0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.3	PID IFNG PATHWAY	IFN-gamma pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.0	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.0	0.2	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation