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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZNF263

Z-value: 1.17

Motif logo

Transcription factors associated with ZNF263

Gene Symbol	Gene ID	Gene Info
ZNF263 Ensembl NCBI GeneCards UniProt	ENSG00000006194.6	ZNF263

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ZNF263	chr16_3335112_3335263	1232	0.296227	0.76	1.7e-02	Click!
ZNF263	chr16_3313763_3313914	38	0.953104	0.73	2.5e-02	Click!
ZNF263	chr16_3313217_3313368	508	0.646727	0.71	3.1e-02	Click!
ZNF263	chr16_3317257_3317408	3532	0.128241	-0.59	9.4e-02	Click!
ZNF263	chr16_3332408_3332578	450	0.693266	0.58	9.9e-02	Click!

Activity of the ZNF263 motif across conditions

Conditions sorted by the z-value of the ZNF263 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr20_3797166_3797457	0.28	AP5S1	adaptor-related protein complex 5, sigma 1 subunit	3867	0.15
chr1_55266187_55266338	0.28	TTC22	tetratricopeptide repeat domain 22	609	0.65
chr17_72595359_72595719	0.26	CD300LD	CD300 molecule-like family member d	7117	0.13
chr2_127729248_127729399	0.26	ENSG00000238788	.	45674	0.17
chr9_138999867_139000258	0.26	C9orf69	chromosome 9 open reading frame 69	10058	0.19
chr16_89521002_89521377	0.24	ENSG00000252887	.	11463	0.12
chr8_49427524_49427700	0.23	RP11-770E5.1		36515	0.23
chr17_80259260_80259561	0.23	CD7	CD7 molecule	16018	0.1
chr22_25508368_25508519	0.23	CTA-221G9.11		216	0.95
chr11_68457544_68457869	0.22	GAL	galanin/GMAP prepropeptide	5763	0.21
chr22_23566366_23566517	0.22	BCR	breakpoint cluster region	29706	0.13
chr2_28600951_28601321	0.22	FOSL2	FOS-like antigen 2	14533	0.17
chr11_57136182_57136499	0.21	ENSG00000266018	.	9144	0.09
chr20_61407593_61408050	0.21	LINC00659	long intergenic non-protein coding RNA 659	1057	0.39
chr17_27950485_27950636	0.21	CORO6	coronin 6	638	0.44
chr16_30066961_30067112	0.21	ALDOA	aldolase A, fructose-bisphosphate	2581	0.11
chr20_62845919_62846070	0.21	PCMTD2	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2	41100	0.13
chr11_117882452_117882916	0.20	IL10RA	interleukin 10 receptor, alpha	25575	0.15
chr9_132164240_132164415	0.20	ENSG00000242281	.	31587	0.18
chr6_166874425_166874576	0.20	RPS6KA2-IT1	RPS6KA2 intronic transcript 1 (non-protein coding)	4371	0.23
chr17_20601486_20601637	0.20	AC126365.1		18235	0.23
chr17_65373943_65374094	0.19	PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1	94	0.96
chr17_47950241_47950535	0.18	TAC4	tachykinin 4 (hemokinin)	25009	0.14
chr2_235334574_235334725	0.18	ARL4C	ADP-ribosylation factor-like 4C	70595	0.14
chr12_113639204_113639355	0.18	RP11-545P7.4		9313	0.1
chr12_54348960_54349111	0.18	HOXC12	homeobox C12	417	0.63
chr11_62313084_62313252	0.18	AHNAK	AHNAK nucleoprotein	9	0.8
chr1_23853702_23853911	0.18	E2F2	E2F transcription factor 2	3906	0.21
chr3_9849767_9849918	0.18	TTLL3	tubulin tyrosine ligase-like family, member 3	72	0.94
chr3_193813473_193813706	0.18	RP11-135A1.2		35401	0.16
chr17_72375971_72376220	0.18	GPR142	G protein-coupled receptor 142	12498	0.11
chr4_2044269_2044420	0.17	C4orf48	chromosome 4 open reading frame 48	567	0.49
chr11_72341844_72341995	0.17	ENSG00000251919	.	9109	0.12
chr5_11903547_11903743	0.17	CTNND2	catenin (cadherin-associated protein), delta 2	148	0.98
chr8_68492957_68493108	0.17	ENSG00000221660	.	130835	0.05
chr22_38452518_38452669	0.17	PICK1	protein interacting with PRKCA 1	275	0.85
chr20_50110567_50110817	0.17	ENSG00000266761	.	41178	0.17
chr15_61112193_61112344	0.17	RP11-554D20.1		55329	0.15
chr3_42574397_42574567	0.17	VIPR1-AS1	VIPR1 antisense RNA 1	241	0.91
chr3_52260172_52260418	0.17	TLR9	toll-like receptor 9	116	0.93
chr3_184210381_184210566	0.17	EIF2B5-IT1	EIF2B5 intronic transcript 1 (non-protein coding)	12428	0.18
chr4_919824_920024	0.17	GAK	cyclin G associated kinase	6162	0.15
chr14_64340480_64340720	0.16	SYNE2	spectrin repeat containing, nuclear envelope 2	20868	0.2
chr2_11918313_11918555	0.16	LPIN1	lipin 1	1101	0.46
chr15_85264710_85265101	0.16	SEC11A	SEC11 homolog A (S. cerevisiae)	4958	0.15
chr14_98605237_98605600	0.16	C14orf64	chromosome 14 open reading frame 64	160957	0.04
chr3_9216538_9216718	0.16	SRGAP3-AS2	SRGAP3 antisense RNA 2	17549	0.2
chr9_92056249_92056678	0.16	SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	5065	0.28
chr8_90770527_90770756	0.16	RIPK2	receptor-interacting serine-threonine kinase 2	579	0.85
chr19_17866005_17866156	0.16	FCHO1	FCH domain only 1	173	0.92
chr10_135089230_135089517	0.16	ADAM8	ADAM metallopeptidase domain 8	981	0.37
chr12_53491063_53491363	0.16	IGFBP6	insulin-like growth factor binding protein 6	7	0.96
chr1_202807089_202807240	0.16	RP11-480I12.4	Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515	14779	0.11
chr1_185703151_185703455	0.16	HMCN1	hemicentin 1	380	0.92
chr16_85824204_85824355	0.16	RP11-568J23.6		1742	0.22
chr15_41139931_41140177	0.16	SPINT1	serine peptidase inhibitor, Kunitz type 1	3181	0.13
chr20_60815943_60816281	0.16	OSBPL2	oxysterol binding protein-like 2	2532	0.22
chr15_90589944_90590197	0.16	ZNF710	zinc finger protein 710	21176	0.13
chr22_46441880_46442031	0.16	RP6-109B7.5		7018	0.11
chr3_125076231_125076382	0.16	ZNF148	zinc finger protein 148	182	0.95
chr1_89148088_89148249	0.16	PKN2	protein kinase N2	1737	0.38
chr20_61590344_61590759	0.16	SLC17A9	solute carrier family 17 (vesicular nucleotide transporter), member 9	6153	0.16
chr8_145039399_145039762	0.16	PLEC	plectin	6613	0.1
chr10_133734968_133735119	0.16	PPP2R2D	protein phosphatase 2, regulatory subunit B, delta	12912	0.25
chr8_22962438_22962732	0.15	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	2151	0.23
chr4_57520075_57520276	0.15	HOPX	HOP homeobox	2295	0.37
chr16_2643052_2643206	0.15	CTD-3126B10.1		6590	0.08
chr19_51522550_51522762	0.15	KLK10	kallikrein-related peptidase 10	364	0.67
chr12_48167663_48168087	0.15	SLC48A1	solute carrier family 48 (heme transporter), member 1	884	0.48
chr14_23012176_23012454	0.15	AE000662.92	Uncharacterized protein	13219	0.1
chr8_69244650_69244960	0.15	RP11-664D7.4	HCG1787533; Uncharacterized protein	1079	0.45
chr22_17578526_17578936	0.15	IL17RA	interleukin 17 receptor A	12882	0.15
chr17_77765785_77765936	0.15	CBX8	chromobox homolog 8	5055	0.14
chr22_40588954_40589156	0.15	TNRC6B	trinucleotide repeat containing 6B	15109	0.25
chr22_42319272_42319423	0.15	ENSG00000263463	.	46	0.95
chr8_142292607_142292758	0.15	SLC45A4	solute carrier family 45, member 4	25722	0.11
chr14_61114056_61114513	0.15	SIX1	SIX homeobox 1	1896	0.38
chr19_10873173_10873454	0.15	ENSG00000265879	.	17617	0.11
chr4_38869527_38869678	0.15	ENSG00000207944	.	51	0.65
chr8_27220300_27220714	0.15	PTK2B	protein tyrosine kinase 2 beta	17661	0.21
chr4_57519801_57519998	0.15	HOPX	HOP homeobox	2571	0.35
chr2_102195024_102195175	0.15	RFX8	RFX family member 8, lacking RFX DNA binding domain	103934	0.07
chr14_24800620_24800771	0.15	ADCY4	adenylate cyclase 4	2021	0.13
chr18_77285273_77285750	0.15	AC018445.1	Uncharacterized protein	9454	0.28
chr17_73840969_73841154	0.15	UNC13D	unc-13 homolog D (C. elegans)	263	0.81
chr4_57842862_57843013	0.15	POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	951	0.46
chr4_55550779_55550930	0.15	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	26769	0.26
chr17_78997298_78997556	0.15	BAIAP2	BAI1-associated protein 2	11523	0.11
chr14_100549307_100549458	0.15	CTD-2376I20.1		8167	0.14
chr18_77444865_77445106	0.15	CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	4136	0.28
chr2_231523692_231523963	0.15	CAB39	calcium binding protein 39	53733	0.12
chr2_74640419_74640570	0.15	C2orf81	chromosome 2 open reading frame 81	3216	0.11
chr11_125364970_125365121	0.15	AP000708.1		65	0.89
chr1_206911037_206911373	0.15	ENSG00000199349	.	10232	0.16
chr17_16963870_16964021	0.15	MPRIP-AS1	MPRIP antisense RNA 1	17121	0.16
chr1_202613330_202613596	0.15	SYT2	synaptotagmin II	882	0.64
chr17_61505350_61505582	0.15	RP11-269G24.3		2984	0.18
chr22_44588585_44588736	0.15	PARVG	parvin, gamma	10919	0.27
chr17_47563928_47564144	0.15	NGFR	nerve growth factor receptor	8619	0.16
chr17_38078750_38078991	0.15	ORMDL3	ORM1-like 3 (S. cerevisiae)	1586	0.26
chr1_6647040_6647244	0.15	ZBTB48	zinc finger and BTB domain containing 48	6994	0.12
chr17_76169100_76169420	0.14	SYNGR2	synaptogyrin 2	4021	0.13
chr12_133070720_133070943	0.14	FBRSL1	fibrosin-like 1	3674	0.25
chr19_42382585_42382736	0.14	CD79A	CD79a molecule, immunoglobulin-associated alpha	1285	0.3
chr10_135089640_135089818	0.14	ADAM8	ADAM metallopeptidase domain 8	625	0.55
chr9_139984075_139984226	0.14	MAN1B1	mannosidase, alpha, class 1B, member 1	517	0.47
chr1_43202897_43203048	0.14	CLDN19	claudin 19	2839	0.19
chr16_68389761_68390217	0.14	SMPD3	sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)	14919	0.11
chr1_108639612_108639804	0.14	ENSG00000264753	.	78315	0.09
chr2_169326472_169326666	0.14	CERS6	ceramide synthase 6	13810	0.19
chr18_46363588_46363739	0.14	RP11-484L8.1		2522	0.38
chr17_75321389_75321609	0.14	SEPT9	septin 9	2807	0.3
chr2_191888300_191888451	0.14	ENSG00000231858	.	2123	0.26
chr10_126340129_126340372	0.14	FAM53B-AS1	FAM53B antisense RNA 1	51944	0.14
chr15_71184789_71184970	0.14	LRRC49	leucine rich repeat containing 49	86	0.56
chr9_130646557_130646708	0.14	AK1	adenylate kinase 1	6610	0.09
chr13_46424723_46424991	0.14	SIAH3	siah E3 ubiquitin protein ligase family member 3	1014	0.66
chr8_123807540_123807790	0.14	RP11-44N11.1		12320	0.2
chr14_35838842_35838993	0.14	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	34429	0.18
chr2_113934390_113934860	0.14	AC016683.5		1688	0.27
chr3_52252083_52252475	0.14	ALAS1	aminolevulinate, delta-, synthase 1	6811	0.1
chr5_133414981_133415351	0.14	TCF7	transcription factor 7 (T-cell specific, HMG-box)	35236	0.17
chr9_136207173_136207324	0.14	ENSG00000201451	.	2587	0.1
chr2_27071961_27072112	0.14	DPYSL5	dihydropyrimidinase-like 5	660	0.72
chr5_156340854_156341043	0.14	TIMD4	T-cell immunoglobulin and mucin domain containing 4	21739	0.23
chr8_130986225_130986492	0.14	FAM49B	family with sequence similarity 49, member B	3122	0.25
chr18_74331596_74331936	0.14	LINC00908	long intergenic non-protein coding RNA 908	90892	0.08
chr1_1727926_1728077	0.14	NADK	NAD kinase	16493	0.13
chr6_41610672_41610823	0.14	MDFI	MyoD family inhibitor	4482	0.18
chr5_40409577_40409881	0.14	ENSG00000265615	.	89309	0.09
chr1_204449452_204449603	0.14	PIK3C2B	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta	9919	0.19
chr2_239348111_239348262	0.14	AC016999.2		11816	0.17
chr22_47082243_47082590	0.14	GRAMD4	GRAM domain containing 4	11911	0.22
chr5_133438573_133438747	0.14	TCF7	transcription factor 7 (T-cell specific, HMG-box)	11742	0.22
chr10_82262907_82263118	0.14	RP11-137H2.4		32686	0.15
chr8_144949231_144949382	0.14	EPPK1	epiplakin 1	3326	0.13
chr17_71585145_71585420	0.14	RP11-277J6.2		51883	0.13
chr12_113529694_113529845	0.14	DTX1	deltex homolog 1 (Drosophila)	34274	0.11
chr7_44089524_44089675	0.14	DBNL	drebrin-like	244	0.84
chr1_19271396_19271573	0.14	IFFO2	intermediate filament family orphan 2	10708	0.19
chr3_149375939_149376119	0.14	WWTR1-AS1	WWTR1 antisense RNA 1	32	0.63
chr7_45013773_45014009	0.14	MYO1G	myosin IG	4806	0.15
chr18_13453029_13453180	0.14	ENSG00000266146	.	6842	0.11
chr16_75609997_75610148	0.14	GABARAPL2	GABA(A) receptor-associated protein-like 2	9576	0.12
chr16_23846475_23846805	0.14	PRKCB	protein kinase C, beta	682	0.76
chr14_105648942_105649093	0.14	NUDT14	nudix (nucleoside diphosphate linked moiety X)-type motif 14	1377	0.39
chr10_73092924_73093094	0.13	ENSG00000238918	.	7924	0.21
chr10_134233485_134233667	0.13	RP11-432J24.3		21412	0.15
chr20_32603638_32604045	0.13	RALY	RALY heterogeneous nuclear ribonucleoprotein	13826	0.19
chr5_56012766_56012917	0.13	MAP3K1	mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase	98560	0.07
chr16_88764542_88764951	0.13	RNF166	ring finger protein 166	1368	0.18
chr13_100622365_100622599	0.13	ZIC5	Zic family member 5	1681	0.37
chr10_119589917_119590068	0.13	RP11-354M20.3		187006	0.03
chr17_76247879_76248079	0.13	TMEM235	transmembrane protein 235	19857	0.13
chr5_149837059_149837232	0.13	RPS14	ribosomal protein S14	7826	0.18
chr2_232389343_232389501	0.13	NMUR1	neuromedin U receptor 1	5784	0.15
chr21_45574089_45574422	0.13	C21orf33	chromosome 21 open reading frame 33	18254	0.13
chr7_4225177_4225328	0.13	SDK1	sidekick cell adhesion molecule 1	234700	0.02
chr12_15116052_15116331	0.13	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	1529	0.36
chr20_31494199_31494350	0.13	EFCAB8	EF-hand calcium binding domain 8	5185	0.22
chr22_30087878_30088029	0.13	RP1-76B20.12		27750	0.11
chr2_97553546_97553697	0.13	FAM178B	family with sequence similarity 178, member B	10249	0.14
chr1_212768754_212768905	0.13	ATF3	activating transcription factor 3	13183	0.15
chr8_134560784_134561068	0.13	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	23166	0.26
chr6_34214917_34215068	0.13	C6orf1	chromosome 6 open reading frame 1	1774	0.38
chr19_2041628_2041930	0.13	MKNK2	MAP kinase interacting serine/threonine kinase 2	302	0.81
chr7_27280334_27280485	0.13	EVX1	even-skipped homeobox 1	1755	0.2
chr7_157664851_157665002	0.13	RP11-452C13.1		3696	0.29
chrX_55026096_55026340	0.13	APEX2	APEX nuclease (apurinic/apyrimidinic endonuclease) 2	572	0.63
chr9_108621156_108621441	0.13	TMEM38B	transmembrane protein 38B	137330	0.05
chr13_32605853_32606039	0.13	FRY-AS1	FRY antisense RNA 1	170	0.82
chr13_111176889_111177040	0.13	COL4A2-AS1	COL4A2 antisense RNA 1	16438	0.19
chr1_26453922_26454389	0.13	PDIK1L	PDLIM1 interacting kinase 1 like	15815	0.1
chr5_141095035_141095247	0.13	ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	33353	0.13
chr17_46656352_46656639	0.13	HOXB3	homeobox B3	224	0.71
chr8_17577421_17577572	0.13	MTUS1	microtubule associated tumor suppressor 1	2234	0.27
chr7_50425191_50425522	0.13	IKZF1	IKAROS family zinc finger 1 (Ikaros)	58111	0.13
chr9_130718207_130718501	0.13	FAM102A	family with sequence similarity 102, member A	5353	0.11
chr5_149837341_149837528	0.13	RPS14	ribosomal protein S14	8115	0.18
chr18_77162255_77162406	0.13	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	1938	0.41
chr2_37779307_37779458	0.13	AC006369.2		47897	0.16
chr3_69417510_69417887	0.13	FRMD4B	FERM domain containing 4B	14850	0.29
chr22_45100692_45100909	0.13	ARHGAP8	Rho GTPase activating protein 8	2418	0.24
chr7_150328231_150328412	0.13	GIMAP6	GTPase, IMAP family member 6	1113	0.51
chr20_21082919_21083126	0.13	ENSG00000199509	.	36693	0.19
chr14_102293009_102293176	0.13	CTD-2017C7.1		12776	0.15
chr5_55996802_55997055	0.13	AC022431.2	Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.	94869	0.07
chr19_38851998_38852149	0.13	AC005625.1		1051	0.28
chr2_85805310_85805461	0.13	VAMP8	vesicle-associated membrane protein 8	669	0.48
chr7_150429368_150429567	0.13	GIMAP5	GTPase, IMAP family member 5	4969	0.18
chr1_26634897_26635082	0.13	UBXN11	UBX domain protein 11	1509	0.27
chr22_47021452_47021710	0.13	GRAMD4	GRAM domain containing 4	1077	0.6
chr5_175956210_175956448	0.13	RNF44	ring finger protein 44	1317	0.33
chr18_74138582_74138815	0.13	ZNF516	zinc finger protein 516	47830	0.13
chr19_51054807_51054958	0.13	LRRC4B	leucine rich repeat containing 4B	583	0.63
chr4_2262785_2262953	0.13	MXD4	MAX dimerization protein 4	1152	0.37
chr1_182057775_182057926	0.13	ZNF648	zinc finger protein 648	27003	0.26
chr5_137358751_137358987	0.13	RP11-325L7.1		9594	0.14
chr20_31070142_31070366	0.13	C20orf112	chromosome 20 open reading frame 112	1020	0.54
chr19_1840869_1841314	0.12	REXO1	REX1, RNA exonuclease 1 homolog (S. cerevisiae)	7361	0.08

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF263

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.2	GO:0032621	interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1	0.3	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.1	0.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.2	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.6	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.2	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1	0.2	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.1	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.2	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.2	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1	0.2	GO:0014055	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1	0.2	GO:0046137	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) membrane raft localization(GO:0051665)
0.1	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.2	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.2	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.1	0.2	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.2	GO:0060430	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.1	0.3	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.1	0.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.2	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0002323	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.0	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.4	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.2	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.2	GO:0045625	regulation of T-helper 1 cell differentiation(GO:0045625)
0.0	0.0	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.2	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0	0.2	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0048799	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0010979	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.2	GO:0060346	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.1	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.2	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.2	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.1	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.1	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.3	GO:0051155	positive regulation of striated muscle cell differentiation(GO:0051155)
0.0	0.1	GO:0015809	arginine transport(GO:0015809)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.0	GO:0009912	auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.2	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.0	0.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0	0.1	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.2	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.0	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.0	0.2	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.2	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.1	GO:0001878	response to yeast(GO:0001878)
0.0	0.1	GO:1901538	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.2	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.2	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.1	GO:0045588	gamma-delta T cell differentiation(GO:0042492) regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588) regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.3	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0072162	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.1	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.1	GO:0060976	coronary vasculature development(GO:0060976)
0.0	0.1	GO:0048563	post-embryonic organ morphogenesis(GO:0048563)
0.0	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.0	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.4	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.1	GO:0051284	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0	0.1	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.1	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.0	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.1	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.0	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.0	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0010755	regulation of plasminogen activation(GO:0010755)
0.0	0.0	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
0.0	0.2	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.0	GO:0033004	negative regulation of mast cell activation(GO:0033004) regulation of action potential(GO:0098900)
0.0	0.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.0	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0046398	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0	0.0	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.1	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.2	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.2	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0017014	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.5	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.1	GO:0055025	positive regulation of cardiac muscle tissue growth(GO:0055023) positive regulation of cardiac muscle tissue development(GO:0055025) positive regulation of cardiac muscle cell proliferation(GO:0060045) positive regulation of heart growth(GO:0060421)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.0	GO:1902117	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803) positive regulation of organelle assembly(GO:1902117)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.0	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.3	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.1	GO:0042269	regulation of natural killer cell mediated immunity(GO:0002715) regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.0	GO:0071503	response to heparin(GO:0071503)
0.0	0.0	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.1	GO:0097154	GABAergic neuron differentiation(GO:0097154)
0.0	0.1	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.3	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.0	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:0048305	immunoglobulin secretion(GO:0048305) regulation of immunoglobulin secretion(GO:0051023)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.0	GO:2000321	T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0	0.1	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.5	GO:0050771	negative regulation of axonogenesis(GO:0050771)
0.0	0.0	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament organization(GO:0031033) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.2	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0003181	atrioventricular valve development(GO:0003171) atrioventricular valve morphogenesis(GO:0003181)
0.0	0.1	GO:0036473	intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) cell death in response to oxidative stress(GO:0036473)
0.0	0.1	GO:0002097	tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0072505	phosphate ion homeostasis(GO:0055062) divalent inorganic anion homeostasis(GO:0072505) trivalent inorganic anion homeostasis(GO:0072506)
0.0	0.0	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0	0.3	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.2	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.0	GO:0060057	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.2	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.3	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0021795	cerebral cortex cell migration(GO:0021795)
0.0	0.1	GO:0050798	activated T cell proliferation(GO:0050798)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.0	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.1	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.0	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.0	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.0	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:1901072	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.0	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.0	GO:0051775	response to redox state(GO:0051775)
0.0	0.1	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.0	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0050687	negative regulation of defense response to virus(GO:0050687)
0.0	0.0	GO:0003416	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.0	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.0	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.0	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.0	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0002691	regulation of cellular extravasation(GO:0002691)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
0.0	0.1	GO:0051926	negative regulation of calcium ion transport(GO:0051926)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.0	GO:1903429	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.0	GO:0090036	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.3	GO:0006305	DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0	0.0	GO:0003197	endocardial cushion development(GO:0003197)
0.0	0.1	GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein(GO:0042522)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.0	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.0	0.0	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0	0.1	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0030146	obsolete diuresis(GO:0030146)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.2	GO:0097581	lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0	0.0	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.0	0.0	GO:0090023	positive regulation of neutrophil chemotaxis(GO:0090023) positive regulation of neutrophil migration(GO:1902624)
0.0	0.0	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.0	GO:0060592	mammary gland formation(GO:0060592) mammary gland specification(GO:0060594)
0.0	0.2	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.0	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0051580	regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0	0.2	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.1	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0048668	collateral sprouting(GO:0048668)
0.0	0.1	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.7	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.0	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.0	GO:0033088	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.2	GO:0030901	midbrain development(GO:0030901)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0051000	positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.0	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.2	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.2	GO:0007398	ectoderm development(GO:0007398)
0.0	0.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.0	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.2	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0006984	ER-nucleus signaling pathway(GO:0006984)
0.0	0.1	GO:0015780	nucleotide-sugar transport(GO:0015780)
0.0	0.1	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.0	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0035089	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0	0.1	GO:0030201	heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0	0.5	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.1	GO:0000154	rRNA modification(GO:0000154)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.0	GO:0002329	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.0	0.0	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.0	GO:0031529	ruffle organization(GO:0031529)
0.0	0.0	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.0	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0019883	antigen processing and presentation of endogenous antigen(GO:0019883)
0.0	0.0	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.0	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.0	0.0	GO:0045606	positive regulation of epidermal cell differentiation(GO:0045606) positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.1	GO:0021884	forebrain neuron development(GO:0021884)
0.0	0.0	GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.0	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.0	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.0	GO:0031058	positive regulation of histone modification(GO:0031058)
0.0	0.1	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	0.1	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.0	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.2	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.0	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.3	GO:0043488	regulation of mRNA stability(GO:0043488)
0.0	0.5	GO:0006968	cellular defense response(GO:0006968)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.0	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.1	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0035094	response to nicotine(GO:0035094)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0090399	replicative senescence(GO:0090399)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.2	GO:0032272	negative regulation of protein polymerization(GO:0032272)
0.0	0.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0	0.0	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0003091	renal water homeostasis(GO:0003091)
0.0	0.0	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0042772	DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.0	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.0	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0031645	negative regulation of neurological system process(GO:0031645)
0.0	0.2	GO:0036260	7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.0	0.0	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0042226	interleukin-6 biosynthetic process(GO:0042226)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.1	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.0	GO:0071624	positive regulation of granulocyte chemotaxis(GO:0071624)
0.0	0.0	GO:1901796	regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516) regulation of signal transduction by p53 class mediator(GO:1901796)
0.0	0.0	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0070820	tertiary granule(GO:0070820)
0.1	0.2	GO:0043218	compact myelin(GO:0043218)
0.1	0.2	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.2	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.0	GO:0070938	contractile ring(GO:0070938)
0.0	0.3	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.0	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.5	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.3	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0098984	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.2	GO:0034362	low-density lipoprotein particle(GO:0034362)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.7	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.3	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0070603	SWI/SNF superfamily-type complex(GO:0070603)
0.0	0.3	GO:0032421	stereocilium bundle(GO:0032421)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.0	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.2	GO:0042588	zymogen granule(GO:0042588)
0.0	0.0	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.0	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0099738	cell cortex region(GO:0099738)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.0	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.0	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.2	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.2	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.3	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.2	GO:0005042	netrin receptor activity(GO:0005042)
0.1	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.1	0.2	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.2	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.2	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.1	GO:0015254	glycerol channel activity(GO:0015254)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.4	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.2	GO:0009922	fatty acid elongase activity(GO:0009922)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.3	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0	0.2	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.3	GO:0030553	cGMP binding(GO:0030553)
0.0	0.2	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.5	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	1.0	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.3	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.2	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.0	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0000400	four-way junction DNA binding(GO:0000400)
0.0	0.2	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.2	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.0	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.0	GO:0042806	fucose binding(GO:0042806)
0.0	0.1	GO:0008106	alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0008556	potassium-transporting ATPase activity(GO:0008556)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0017166	vinculin binding(GO:0017166)
0.0	0.0	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.0	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.0	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.1	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.3	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.6	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.0	GO:0001848	complement binding(GO:0001848)
0.0	0.3	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.0	GO:0005035	death receptor activity(GO:0005035)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.0	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.0	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.0	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0	0.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.0	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.2	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.0	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.0	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.0	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.0	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.6	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3	ST STAT3 PATHWAY	STAT3 Pathway
0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.4	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.6	PID TRAIL PATHWAY	TRAIL signaling pathway
1.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.4	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.3	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.3	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.1	PID EPO PATHWAY	EPO signaling pathway
0.3	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.3	PID BCR 5PATHWAY	BCR signaling pathway
0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.3	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.4	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.2	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	PID CDC42 PATHWAY	CDC42 signaling events
0.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.3	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	0.7	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.0	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.4	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.5	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.5	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.4	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.3	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.4	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.4	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.2	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.0	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.3	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.0	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.0	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.0	0.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.0	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.2	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.0	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.4	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.0	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.2	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.0	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.2	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.0	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.3	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.0	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events