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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ZNF282

Z-value: 1.24

Motif logo

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Transcription factors associated with ZNF282

Gene Symbol Gene ID Gene Info
ZNF282
ENSG00000170265.7 zinc finger protein 282

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_148893289_148893440ZNF2827220.6276420.909.7e-04Click!
chr7_148893510_148893675ZNF2829500.5160320.872.5e-03Click!
chr7_148878722_148878873ZNF282137800.144296-0.742.1e-02Click!
chr7_148888859_148889047ZNF28236240.1951900.693.9e-02Click!
chr7_148877933_148878084ZNF282145690.142631-0.674.9e-02Click!

Activity of the ZNF282 motif across conditions

Conditions sorted by the z-value of the ZNF282 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_46572017_46572193 0.70 SLC38A1
 solute carrier family 38, member 1
 89379
 0.1
chr2_96830073_96830240 0.65 DUSP2
 dual specificity phosphatase 2
 18977
 0.13
chr7_142502062_142502213 0.55 PRSS3P2
 protease, serine, 3 pseudogene 2
 21006
 0.16
chr10_82288993_82289258 0.48 RP11-137H2.4
6573
 0.22
chr1_109188369_109188646 0.47 HENMT1
 HEN1 methyltransferase homolog 1 (Arabidopsis)
 15170
 0.19
chr12_6573393_6573619 0.47 VAMP1
 vesicle-associated membrane protein 1 (synaptobrevin 1)
 6305
 0.09
chr20_13619077_13619233 0.46 TASP1
 taspase, threonine aspartase, 1
 395
 0.92
chr6_36067796_36067952 0.45 MAPK13
 mitogen-activated protein kinase 13
 30224
 0.14
chr7_3020531_3020974 0.44 ENSG00000201794
 .
 17976
 0.2
chr2_55757616_55757885 0.42 CCDC104
 coiled-coil domain containing 104
 10883
 0.15
chr11_14292192_14292493 0.42 RP11-21L19.1
2895
 0.33
chr2_234308315_234308480 0.41 DGKD
 diacylglycerol kinase, delta 130kDa
 11597
 0.17
chr14_91302849_91303150 0.41 TTC7B
 tetratricopeptide repeat domain 7B
 20176
 0.25
chr13_30944650_30944977 0.41 KATNAL1
 katanin p60 subunit A-like 1
 63192
 0.13
chr2_7018212_7018651 0.40 RSAD2
 radical S-adenosyl methionine domain containing 2
 494
 0.78
chr8_82044607_82044805 0.40 PAG1
 phosphoprotein associated with glycosphingolipid microdomains 1
 20403
 0.26
chr15_91143512_91143728 0.40 CTD-3065B20.2
3941
 0.18
chr10_7237970_7238148 0.40 SFMBT2
 Scm-like with four mbt domains 2
 212648
 0.02
chr1_117310626_117310883 0.39 CD2
 CD2 molecule
 13665
 0.21
chrX_9286819_9287136 0.39 TBL1X
 transducin (beta)-like 1X-linked
 144358
 0.05
chr18_60880123_60880495 0.39 ENSG00000238988
 .
 18411
 0.21
chr19_47948776_47948927 0.39 MEIS3
 Meis homeobox 3
 26071
 0.11
chr14_89817017_89817302 0.38 RP11-356K23.1
513
 0.77
chr1_111433483_111434153 0.37 CD53
 CD53 molecule
 18042
 0.16
chrX_103367091_103367582 0.37 ZCCHC18
 zinc finger, CCHC domain containing 18
 10134
 0.18
chr20_50097371_50097649 0.37 ENSG00000266761
 .
 27996
 0.21
chr7_150200817_150201275 0.37 GIMAP7
 GTPase, IMAP family member 7
 10872
 0.18
chr17_37252182_37252943 0.37 PLXDC1
 plexin domain containing 1
 11178
 0.15
chr7_142378873_142379024 0.37 MTRNR2L6
 MT-RNR2-like 6
 4844
 0.28
chr8_129672236_129672673 0.37 ENSG00000221351
 .
 159586
 0.04
chr1_101745654_101745926 0.37 RP4-575N6.5
37076
 0.14
chr1_117903396_117903547 0.37 MAN1A2
 mannosidase, alpha, class 1A, member 2
 6600
 0.31
chr9_20373431_20373643 0.36 MLLT3
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
 8930
 0.21
chr16_84119947_84120139 0.36 MBTPS1
 membrane-bound transcription factor peptidase, site 1
 30357
 0.1
chr12_65672789_65672940 0.36 MSRB3
 methionine sulfoxide reductase B3
 97
 0.97
chr3_50611684_50611927 0.36 HEMK1
 HemK methyltransferase family member 1
 2750
 0.2
chr17_37911699_37911850 0.36 GRB7
 growth factor receptor-bound protein 7
 13269
 0.11
chr4_2787896_2788215 0.35 SH3BP2
 SH3-domain binding protein 2
 6695
 0.21
chr18_2636269_2636739 0.35 ENSG00000200875
 .
 13362
 0.14
chr3_32411752_32412018 0.35 CMTM7
 CKLF-like MARVEL transmembrane domain containing 7
 21278
 0.22
chr5_156630874_156631025 0.35 CTB-4E7.1
20441
 0.11
chr4_108984413_108984564 0.35 HADH
 hydroxyacyl-CoA dehydrogenase
 58697
 0.12
chr6_37141344_37141568 0.35 PIM1
 pim-1 oncogene
 3477
 0.23
chrX_135839770_135839921 0.34 ARHGEF6
 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
 9657
 0.18
chr5_158239944_158240095 0.34 CTD-2363C16.1
169995
 0.04
chr15_38982599_38982925 0.34 C15orf53
 chromosome 15 open reading frame 53
 6037
 0.31
chr17_17660810_17661016 0.34 RAI1-AS1
 RAI1 antisense RNA 1
 13222
 0.13
chr6_36005080_36005248 0.34 MAPK14
 mitogen-activated protein kinase 14
 8298
 0.19
chr18_29606522_29606811 0.34 RNF125
 ring finger protein 125, E3 ubiquitin protein ligase
 8331
 0.16
chr5_67577719_67577949 0.34 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 1699
 0.51
chr9_116288167_116288318 0.33 RGS3
 regulator of G-protein signaling 3
 8692
 0.23
chr1_245020022_245020173 0.33 HNRNPU-AS1
 HNRNPU antisense RNA 1
 1298
 0.41
chr3_13462874_13463150 0.33 NUP210
 nucleoporin 210kDa
 1203
 0.55
chr3_4334985_4335136 0.33 SETMAR
 SET domain and mariner transposase fusion gene
 9928
 0.31
chr14_103368353_103368504 0.33 AMN
 amnion associated transmembrane protein
 20565
 0.12
chr3_13048597_13048870 0.33 IQSEC1
 IQ motif and Sec7 domain 1
 20197
 0.25
chr3_38005322_38005473 0.32 CTDSPL
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
 673
 0.64
chr16_80598344_80598524 0.32 RP11-525K10.3
1402
 0.4
chr1_235291589_235291740 0.32 ENSG00000207181
 .
 412
 0.58
chr1_54946775_54946928 0.32 ENSG00000265404
 .
 23490
 0.17
chr12_123592299_123592450 0.32 PITPNM2
 phosphatidylinositol transfer protein, membrane-associated 2
 2601
 0.28
chr5_14794238_14794389 0.32 ENSG00000264792
 .
 31808
 0.19
chr15_52046369_52046544 0.32 CTD-2308G16.1
1774
 0.24
chr3_15308861_15309012 0.32 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 8480
 0.14
chrY_2874457_2874608 0.32 ZFY-AS1
 ZFY antisense RNA 1
 3865
 0.34
chr5_169704104_169704255 0.32 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 9848
 0.22
chr3_186678062_186678218 0.32 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 14605
 0.21
chr1_27944687_27944855 0.32 FGR
 feline Gardner-Rasheed sarcoma viral oncogene homolog
 5802
 0.15
chr22_22603206_22603357 0.31 VPREB1
 pre-B lymphocyte 1
 4089
 0.1
chr5_14701641_14701810 0.31 FAM105B
 family with sequence similarity 105, member B
 20066
 0.2
chr2_95688672_95688933 0.31 MAL
 mal, T-cell differentiation protein
 2627
 0.21
chr17_35447597_35447771 0.31 ACACA
 acetyl-CoA carboxylase alpha
 1766
 0.34
chr14_105532821_105533069 0.31 GPR132
 G protein-coupled receptor 132
 1163
 0.49
chr11_124813257_124813486 0.31 HEPACAM
 hepatic and glial cell adhesion molecule
 7063
 0.13
chr5_39175704_39176163 0.31 FYB
 FYN binding protein
 27196
 0.22
chr17_14221651_14221911 0.31 HS3ST3B1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
 17381
 0.25
chr11_118182213_118182479 0.31 CD3E
 CD3e molecule, epsilon (CD3-TCR complex)
 6732
 0.13
chr13_42070374_42070546 0.31 RGCC
 regulator of cell cycle
 38765
 0.13
chr3_43343792_43343998 0.31 ENSG00000241939
 .
 12548
 0.17
chr18_13465523_13465878 0.31 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
 686
 0.52
chr21_36409118_36409316 0.31 RUNX1
 runt-related transcription factor 1
 12245
 0.31
chr19_6775713_6775940 0.30 VAV1
 vav 1 guanine nucleotide exchange factor
 2857
 0.17
chr2_169290019_169290449 0.30 ENSG00000239230
 .
 7481
 0.21
chr13_22032610_22032761 0.30 ZDHHC20
 zinc finger, DHHC-type containing 20
 729
 0.72
chr12_11697430_11697755 0.30 ENSG00000251747
 .
 1821
 0.33
chr10_98516773_98516924 0.30 ENSG00000207287
 .
 13924
 0.19
chr7_105525970_105526305 0.30 ATXN7L1
 ataxin 7-like 1
 9087
 0.29
chr8_21772448_21772871 0.30 DOK2
 docking protein 2, 56kDa
 1288
 0.44
chr21_43658442_43658806 0.30 ENSG00000223262
 .
 17341
 0.16
chr3_18412272_18412602 0.30 RP11-158G18.1
38690
 0.18
chr4_40230061_40230375 0.30 RHOH
 ras homolog family member H
 28254
 0.18
chr2_241342781_241342932 0.30 GPC1
 glypican 1
 32232
 0.15
chr15_64128117_64128268 0.30 HERC1
 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
 2051
 0.37
chr2_8596031_8596222 0.30 AC011747.7
219770
 0.02
chr1_12405618_12405821 0.30 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 64205
 0.11
chr19_55764964_55765151 0.30 PPP6R1
 protein phosphatase 6, regulatory subunit 1
 2080
 0.15
chr1_121347938_121348091 0.30 FCGR1B
 Fc fragment of IgG, high affinity Ib, receptor (CD64)
 412077
 0.01
chr20_25676704_25676934 0.29 ZNF337
 zinc finger protein 337
 658
 0.71
chr2_198075189_198075340 0.29 ANKRD44
 ankyrin repeat domain 44
 12502
 0.2
chr7_138728882_138729132 0.29 ZC3HAV1L
 zinc finger CCCH-type, antiviral 1-like
 8232
 0.21
chr12_104912220_104912483 0.29 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 61572
 0.13
chr6_41976653_41976895 0.29 ENSG00000206875
 .
 9478
 0.16
chr19_19051022_19051173 0.29 HOMER3
 homer homolog 3 (Drosophila)
 16
 0.5
chr5_130852523_130852701 0.29 RAPGEF6
 Rap guanine nucleotide exchange factor (GEF) 6
 8762
 0.3
chr18_21059346_21059497 0.29 RIOK3
 RIO kinase 3
 2269
 0.26
chr11_121416006_121416228 0.29 SORL1
 sortilin-related receptor, L(DLR class) A repeats containing
 21317
 0.27
chr10_11364003_11364154 0.29 CELF2-AS1
 CELF2 antisense RNA 1
 2231
 0.44
chr9_134145646_134145833 0.29 FAM78A
 family with sequence similarity 78, member A
 141
 0.96
chr9_37075041_37075192 0.29 RP11-220I1.2
40371
 0.13
chr10_112603695_112603846 0.29 PDCD4
 programmed cell death 4 (neoplastic transformation inhibitor)
 27795
 0.13
chr6_37469689_37469840 0.28 CCDC167
 coiled-coil domain containing 167
 2066
 0.34
chr2_143975242_143975418 0.28 RP11-190J23.1
45589
 0.18
chr17_78721062_78721213 0.28 RP11-28G8.1
58295
 0.13
chr13_52394867_52395060 0.28 RP11-327P2.5
16530
 0.18
chr8_91640248_91640450 0.28 TMEM64
 transmembrane protein 64
 17391
 0.21
chr12_54675160_54675465 0.28 HNRNPA1
 heterogeneous nuclear ribonucleoprotein A1
 342
 0.7
chr2_225895814_225896091 0.28 DOCK10
 dedicator of cytokinesis 10
 11207
 0.25
chr2_106380015_106380293 0.28 NCK2
 NCK adaptor protein 2
 17966
 0.27
chr18_46586685_46586836 0.28 ENSG00000263849
 .
 10622
 0.19
chr5_54398513_54398753 0.28 GZMA
 granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
 157
 0.94
chr4_84028872_84029038 0.28 PLAC8
 placenta-specific 8
 2041
 0.38
chr1_208004097_208004248 0.28 ENSG00000203709
 .
 28304
 0.2
chr12_7344185_7344336 0.28 PEX5
 peroxisomal biogenesis factor 5
 852
 0.49
chr8_61812488_61812744 0.28 RP11-33I11.2
90451
 0.09
chr20_31000245_31000406 0.28 ASXL1
 additional sex combs like 1 (Drosophila)
 18340
 0.18
chr9_77767149_77767402 0.28 ENSG00000200041
 .
 29262
 0.16
chr6_166832217_166832454 0.28 RP1-168L15.5
35658
 0.13
chr10_11236479_11236664 0.28 RP3-323N1.2
23232
 0.2
chr5_133466460_133466611 0.28 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 7226
 0.22
chrX_20264408_20264559 0.28 RPS6KA3
 ribosomal protein S6 kinase, 90kDa, polypeptide 3
 4677
 0.28
chr1_246984990_246985280 0.27 ENSG00000252011
 .
 11696
 0.16
chr1_160832817_160833049 0.27 CD244
 CD244 molecule, natural killer cell receptor 2B4
 241
 0.91
chr2_74248551_74248821 0.27 TET3
 tet methylcytosine dioxygenase 3
 18846
 0.16
chr9_96930007_96930263 0.27 ENSG00000199165
 .
 8099
 0.16
chr15_45879124_45879275 0.27 BLOC1S6
 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
 122
 0.76
chr11_14269963_14270251 0.27 RP11-21L19.1
25130
 0.22
chr14_99672150_99672346 0.27 AL162151.4
47495
 0.14
chr12_102101528_102101679 0.27 CHPT1
 choline phosphotransferase 1
 10153
 0.13
chr22_40571822_40572044 0.27 TNRC6B
 trinucleotide repeat containing 6B
 1996
 0.43
chr6_47276688_47276935 0.27 TNFRSF21
 tumor necrosis factor receptor superfamily, member 21
 830
 0.75
chr21_46271927_46272078 0.27 PTTG1IP
 pituitary tumor-transforming 1 interacting protein
 9846
 0.13
chr21_45509719_45509870 0.27 PWP2
 PWP2 periodic tryptophan protein homolog (yeast)
 17377
 0.16
chr5_175079178_175079630 0.27 HRH2
 histamine receptor H2
 5629
 0.23
chr5_133426970_133427238 0.26 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 23298
 0.2
chr10_30783764_30783915 0.26 MAP3K8
 mitogen-activated protein kinase kinase kinase 8
 56088
 0.12
chr11_64560688_64561099 0.26 MAP4K2
 mitogen-activated protein kinase kinase kinase kinase 2
 9754
 0.11
chr17_38760477_38760676 0.26 SMARCE1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
 27966
 0.12
chr1_162468126_162468277 0.26 UHMK1
 U2AF homology motif (UHM) kinase 1
 568
 0.76
chr15_60864333_60864586 0.26 RORA
 RAR-related orphan receptor A
 20281
 0.19
chr1_27118119_27118479 0.26 PIGV
 phosphatidylinositol glycan anchor biosynthesis, class V
 2880
 0.17
chr11_67368212_67368440 0.26 RP11-655M14.12
4666
 0.1
chr17_26940722_26940873 0.26 SGK494
 uncharacterized serine/threonine-protein kinase SgK494
 382
 0.39
chr12_7252075_7252330 0.26 C1RL
 complement component 1, r subcomponent-like
 2479
 0.15
chr2_12433970_12434170 0.26 ENSG00000264089
 .
 94814
 0.09
chr4_154448725_154449000 0.26 KIAA0922
 KIAA0922
 28186
 0.22
chr13_41054978_41055129 0.26 AL133318.1
 Uncharacterized protein
 56270
 0.14
chr7_114566431_114566590 0.26 MDFIC
 MyoD family inhibitor domain containing
 3379
 0.39
chr20_57828040_57828198 0.26 EDN3
 endothelin 3
 47363
 0.15
chr7_797729_797880 0.26 HEATR2
 HEAT repeat containing 2
 10308
 0.19
chr20_57699560_57699711 0.26 ZNF831
 zinc finger protein 831
 66440
 0.1
chr3_31219913_31220076 0.26 ENSG00000265376
 .
 16715
 0.26
chr16_79229427_79229578 0.26 ENSG00000222244
 .
 68849
 0.11
chr15_60828599_60828948 0.26 CTD-2501E16.2
6601
 0.21
chr12_9905866_9906017 0.26 CD69
 CD69 molecule
 7556
 0.16
chr2_31360077_31360277 0.26 GALNT14
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
 710
 0.75
chr3_49907414_49907654 0.25 CAMKV
 CaM kinase-like vesicle-associated
 121
 0.92
chr12_11694203_11694354 0.25 ENSG00000221128
 .
 701
 0.69
chr4_109061717_109062040 0.25 LEF1
 lymphoid enhancer-binding factor 1
 25579
 0.2
chr10_111846556_111846769 0.25 ADD3
 adducin 3 (gamma)
 78940
 0.09
chr1_172612946_172613385 0.25 FASLG
 Fas ligand (TNF superfamily, member 6)
 14989
 0.23
chr8_128751309_128751460 0.25 MYC
 v-myc avian myelocytomatosis viral oncogene homolog
 2907
 0.36
chr17_4936150_4936301 0.25 SLC52A1
 solute carrier family 52 (riboflavin transporter), member 1
 2496
 0.13
chr1_25947708_25947859 0.25 MAN1C1
 mannosidase, alpha, class 1C, member 1
 3442
 0.25
chr10_134358490_134358742 0.25 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 6973
 0.23
chr12_4257130_4257281 0.25 CCND2
 cyclin D2
 125733
 0.05
chr11_128591622_128591949 0.25 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 25867
 0.16
chr17_38720137_38720288 0.25 CCR7
 chemokine (C-C motif) receptor 7
 1499
 0.37
chr17_75964850_75965001 0.25 TNRC6C
 trinucleotide repeat containing 6C
 35324
 0.15
chr1_172673559_172674098 0.25 FASLG
 Fas ligand (TNF superfamily, member 6)
 45670
 0.18
chr17_32291882_32292036 0.25 RP11-17M24.2
11591
 0.2
chr2_198108993_198109144 0.25 ANKRD44
 ankyrin repeat domain 44
 46306
 0.12
chr5_6485628_6485779 0.25 UBE2QL1
 ubiquitin-conjugating enzyme E2Q family-like 1
 36967
 0.21
chr2_42533183_42533346 0.25 EML4
 echinoderm microtubule associated protein like 4
 4871
 0.28
chr20_18269547_18269794 0.25 ZNF133
 zinc finger protein 133
 492
 0.7
chr9_92070239_92070498 0.25 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 500
 0.85
chr13_100024268_100024596 0.25 ENSG00000207719
 .
 16047
 0.2
chr6_41990355_41990549 0.25 ENSG00000206875
 .
 4200
 0.19
chr14_71788192_71788343 0.25 SIPA1L1
 signal-induced proliferation-associated 1 like 1
 159
 0.64
chr10_73834893_73835167 0.25 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 13056
 0.23
chr17_214026_214483 0.24 RP11-1260E13.3
9726
 0.13
chr22_40333359_40333568 0.24 GRAP2
 GRB2-related adaptor protein 2
 9358
 0.17
chr3_100113716_100113867 0.24 LNP1
 leukemia NUP98 fusion partner 1
 6246
 0.2
chr11_118753286_118753582 0.24 CXCR5
 chemokine (C-X-C motif) receptor 5
 1041
 0.35
chr18_67616654_67616805 0.24 CD226
 CD226 molecule
 1640
 0.51
chr18_21445460_21445673 0.24 LAMA3
 laminin, alpha 3
 7238
 0.23
chr6_41993033_41993209 0.24 ENSG00000206875
 .
 6869
 0.17
chr6_34300867_34301037 0.24 NUDT3
 nudix (nucleoside diphosphate linked moiety X)-type motif 3
 59499
 0.1
chr8_38133631_38133782 0.24 RP11-513D5.5
300
 0.85
chr20_31263204_31263355 0.24 COMMD7
 COMM domain containing 7
 67933
 0.08
chr22_36555180_36555331 0.24 APOL3
 apolipoprotein L, 3
 1576
 0.43

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF282

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.4 GO:0030091 protein repair(GO:0030091)
0.1 0.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.3 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.1 0.2 GO:0045425 positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.1 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.2 GO:0060437 lung growth(GO:0060437)
0.1 0.2 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0002890 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.3 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.2 GO:0002860 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0002837 regulation of response to tumor cell(GO:0002834) positive regulation of response to tumor cell(GO:0002836) regulation of immune response to tumor cell(GO:0002837) positive regulation of immune response to tumor cell(GO:0002839)
0.0 0.1 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0021860 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.1 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.3 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0042663 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:1904936 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.0 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.1 GO:2000258 negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0048143 astrocyte activation(GO:0048143)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.0 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.0 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.8 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.0 GO:0072177 mesonephric duct development(GO:0072177) mesonephric duct morphogenesis(GO:0072180)
0.0 0.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0048194 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.0 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0006356 regulation of transcription from RNA polymerase I promoter(GO:0006356)
0.0 0.0 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.6 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0030146 obsolete diuresis(GO:0030146)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.0 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.0 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.0 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.0 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.0 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.0 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.2 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.2 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.0 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.1 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.0 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.3 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.4 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.0 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.4 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.0 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:0036126 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.2 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.0 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.2 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.3 GO:0061630 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.4 GO:0034979 NAD-dependent protein deacetylase activity(GO:0034979)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0004938 alpha-adrenergic receptor activity(GO:0004936) alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.0 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307) 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.0 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0 0.2 GO:0005035 death receptor activity(GO:0005035)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.0 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.0 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.1 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.1 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.0 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling