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ENCODE: H3K4me1 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZNF350

Z-value: 0.75

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Transcription factors associated with ZNF350

Gene Symbol	Gene ID	Gene Info
ZNF350 Ensembl NCBI GeneCards UniProt	ENSG00000256683.2	ZNF350

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
ZNF350	chr19_52490280_52490507	284	0.854308	0.69	4.1e-02	Click!
ZNF350	chr19_52489445_52489599	401	0.770789	0.38	3.1e-01	Click!
ZNF350	chr19_52489788_52489939	60	0.957996	0.28	4.7e-01	Click!

Activity of the ZNF350 motif across conditions

Conditions sorted by the z-value of the ZNF350 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_79280672_79280844	0.30	RP11-16K12.1		9527	0.18
chr16_11089953_11090104	0.28	CLEC16A	C-type lectin domain family 16, member A	51590	0.09
chr6_41736234_41736385	0.22	FRS3	fibroblast growth factor receptor substrate 3	9610	0.1
chr9_137349078_137349350	0.21	RXRA	retinoid X receptor, alpha	50786	0.15
chr12_25433175_25433326	0.21	KRAS	Kirsten rat sarcoma viral oncogene homolog	29380	0.18
chr7_100182794_100183059	0.20	LRCH4	leucine-rich repeats and calponin homology (CH) domain containing 4	183	0.83
chr1_201719762_201719984	0.20	NAV1	neuron navigator 1	10877	0.12
chr21_32715120_32715271	0.20	TIAM1	T-cell lymphoma invasion and metastasis 1	1399	0.58
chr5_14146856_14147066	0.20	TRIO	trio Rho guanine nucleotide exchange factor	3132	0.4
chr17_80929713_80929864	0.20	RP11-1197K16.2		6613	0.21
chr1_113243152_113243493	0.19	RP11-426L16.3		4079	0.12
chr2_234608672_234608837	0.19	UGT1A6	UDP glucuronosyltransferase 1 family, polypeptide A6	6416	0.1
chr9_124498089_124498240	0.19	DAB2IP	DAB2 interacting protein	6900	0.28
chr11_12863782_12864036	0.18	RP11-47J17.1		6433	0.2
chr20_62686749_62686900	0.18	RP13-152O15.5		1332	0.22
chr11_69257205_69257356	0.18	MYEOV	myeloma overexpressed	195655	0.02
chr20_44978896_44979101	0.18	SLC35C2	solute carrier family 35 (GDP-fucose transporter), member C2	8147	0.2
chr2_220326118_220326333	0.18	SPEG	SPEG complex locus	118	0.93
chr2_20795415_20795848	0.17	HS1BP3-IT1	HS1BP3 intronic transcript 1 (non-protein coding)	3323	0.28
chr20_24929872_24930023	0.17	CST7	cystatin F (leukocystatin)	81	0.97
chr15_70669550_70669810	0.17	ENSG00000200216	.	184105	0.03
chr22_39548986_39549210	0.17	CBX7	chromobox homolog 7	443	0.8
chr11_63381470_63381652	0.16	PLA2G16	phospholipase A2, group XVI	280	0.86
chr12_124781019_124781262	0.16	FAM101A	family with sequence similarity 101, member A	1071	0.61
chr9_72659789_72660086	0.16	MAMDC2	MAM domain containing 2	1440	0.51
chr1_184005215_184005387	0.16	COLGALT2	collagen beta(1-O)galactosyltransferase 2	1310	0.52
chr2_217075636_217075933	0.16	AC012513.6		48534	0.14
chr7_73120336_73120487	0.16	ENSG00000265724	.	5236	0.11
chr3_156806581_156806732	0.16	ENSG00000201778	.	64681	0.09
chr1_182360343_182360566	0.16	GLUL	glutamate-ammonia ligase	85	0.97
chr20_60933838_60933989	0.16	RP11-157P1.5		5844	0.13
chr19_47407713_47407864	0.16	ARHGAP35	Rho GTPase activating protein 35	14145	0.17
chr2_160013505_160013656	0.16	WDSUB1	WD repeat, sterile alpha motif and U-box domain containing 1	129483	0.05
chr9_99482773_99482924	0.16	ZNF510	zinc finger protein 510	57480	0.13
chr10_131330632_131330830	0.15	AL355531.2	Uncharacterized protein	21206	0.22
chr10_43249103_43249301	0.15	BMS1	BMS1 ribosome biogenesis factor	29047	0.19
chr3_57199098_57199350	0.15	IL17RD	interleukin 17 receptor D	179	0.95
chr1_181014307_181014479	0.15	MR1	major histocompatibility complex, class I-related	11254	0.18
chr15_31494061_31494212	0.15	TRPM1	transient receptor potential cation channel, subfamily M, member 1	40660	0.18
chr1_113244311_113244462	0.15	RHOC	ras homolog family member C	3157	0.13
chr6_166874425_166874576	0.15	RPS6KA2-IT1	RPS6KA2 intronic transcript 1 (non-protein coding)	4371	0.23
chr13_113583857_113584008	0.15	MCF2L	MCF.2 cell line derived transforming sequence-like	27423	0.15
chr11_128774089_128774256	0.14	C11orf45	chromosome 11 open reading frame 45	1420	0.38
chr7_17234854_17235017	0.14	AC003075.4		85992	0.1
chr4_1037278_1037479	0.14	FGFRL1	fibroblast growth factor receptor-like 1	31139	0.11
chr5_673661_673812	0.14	CTD-2589H19.6		2205	0.24
chr14_74984739_74984890	0.14	LTBP2	latent transforming growth factor beta binding protein 2	8304	0.16
chr17_55131688_55131839	0.14	AKAP1	A kinase (PRKA) anchor protein 1	30690	0.13
chr14_93043446_93043626	0.14	RIN3	Ras and Rab interactor 3	63388	0.13
chr18_20772119_20772404	0.14	CABLES1	Cdk5 and Abl enzyme substrate 1	36472	0.16
chr9_131936536_131936750	0.14	RP11-247A12.8		1443	0.27
chr11_66650721_66650872	0.14	PC	pyruvate carboxylase	24576	0.11
chr15_70877190_70877341	0.14	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	117355	0.06
chr16_11348403_11348570	0.14	SOCS1	suppressor of cytokine signaling 1	1550	0.21
chr2_87901921_87902194	0.14	ENSG00000265507	.	27217	0.24
chr8_37552274_37552425	0.14	ZNF703	zinc finger protein 703	920	0.47
chr1_3620112_3620445	0.13	TP73	tumor protein p73	5656	0.13
chr11_66823005_66823323	0.13	RHOD	ras homolog family member D	1125	0.44
chr3_169939455_169939857	0.13	PRKCI	protein kinase C, iota	497	0.79
chr3_13323123_13323361	0.13	NUP210	nucleoporin 210kDa	138567	0.05
chr19_36359879_36360032	0.13	APLP1	amyloid beta (A4) precursor-like protein 1	420	0.67
chr3_14494260_14494411	0.13	SLC6A6	solute carrier family 6 (neurotransmitter transporter), member 6	19415	0.22
chr1_22236518_22236840	0.13	HSPG2	heparan sulfate proteoglycan 2	13876	0.16
chr10_115827772_115827923	0.13	ADRB1	adrenoceptor beta 1	24041	0.18
chr3_62573282_62573433	0.13	CADPS	Ca++-dependent secretion activator	2436	0.44
chr6_71666612_71666763	0.13	B3GAT2	beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)	54	0.99
chr1_54764314_54764483	0.13	RP5-997D24.3		13320	0.18
chr19_39423223_39423374	0.13	MRPS12	mitochondrial ribosomal protein S12	1659	0.17
chr6_135504457_135504736	0.13	MYB	v-myb avian myeloblastosis viral oncogene homolog	1944	0.33
chr1_154980745_154981008	0.13	ZBTB7B	zinc finger and BTB domain containing 7B	5581	0.08
chr17_7119350_7119780	0.13	ACADVL	acyl-CoA dehydrogenase, very long chain	879	0.26
chr3_56915864_56916077	0.13	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	34529	0.19
chr17_4693016_4693203	0.13	GLTPD2	glycolipid transfer protein domain containing 2	855	0.36
chr2_73151273_73151429	0.13	EMX1	empty spiracles homeobox 1	234	0.94
chr8_59571402_59571553	0.13	NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor	616	0.76
chr8_31497191_31497379	0.13	NRG1	neuregulin 1	14	0.99
chr4_75858432_75858583	0.13	PARM1	prostate androgen-regulated mucin-like protein 1	181	0.96
chr2_112105742_112105987	0.13	ENSG00000266139	.	27196	0.26
chr5_140887603_140887841	0.13	DIAPH1	diaphanous-related formin 1	17992	0.08
chr1_151483317_151483639	0.13	CGN	cingulin	66	0.95
chr15_91210216_91210381	0.13	RP11-387D10.3		6328	0.17
chr19_36398732_36398883	0.12	TYROBP	TYRO protein tyrosine kinase binding protein	342	0.75
chr15_59739965_59740116	0.12	FAM81A	family with sequence similarity 81, member A	2735	0.25
chr17_33570615_33570828	0.12	SLFN5	schlafen family member 5	613	0.47
chr2_95941109_95941447	0.12	PROM2	prominin 2	1033	0.58
chr16_73191000_73191151	0.12	C16orf47	chromosome 16 open reading frame 47	12729	0.28
chr4_186065139_186065290	0.12	SLC25A4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	819	0.63
chr9_139492984_139493135	0.12	ENSG00000252440	.	3908	0.13
chr11_69251734_69251885	0.12	MYEOV	myeloma overexpressed	190184	0.03
chr11_34267398_34267549	0.12	ENSG00000201867	.	56752	0.14
chr17_39940723_39940965	0.12	JUP	junction plakoglobin	563	0.6
chr4_140871909_140872439	0.12	MAML3	mastermind-like 3 (Drosophila)	60053	0.14
chr22_50707294_50707445	0.12	MAPK11	mitogen-activated protein kinase 11	1424	0.21
chr14_100003657_100003808	0.12	CCDC85C	coiled-coil domain containing 85C	1307	0.41
chr1_27917666_27917818	0.12	AHDC1	AT hook, DNA binding motif, containing 1	12360	0.15
chr5_139046723_139047090	0.12	CXXC5	CXXC finger protein 5	7766	0.22
chr17_38698835_38699076	0.12	CCR7	chemokine (C-C motif) receptor 7	18310	0.15
chr5_175970644_175970798	0.12	CDHR2	cadherin-related family member 2	1209	0.33
chr1_153517829_153518044	0.12	S100A4	S100 calcium binding protein A4	342	0.73
chr20_10551784_10551935	0.12	JAG1	jagged 1	91295	0.08
chr6_90836574_90836725	0.12	ENSG00000222078	.	125424	0.05
chr17_79065717_79065990	0.12	BAIAP2	BAI1-associated protein 2	5526	0.12
chr16_55535078_55535229	0.12	LPCAT2	lysophosphatidylcholine acyltransferase 2	7757	0.22
chr9_133641708_133641929	0.12	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	52451	0.13
chr14_63861661_63861812	0.12	ENSG00000264995	.	67988	0.1
chr15_74248873_74249108	0.12	LOXL1-AS1	LOXL1 antisense RNA 1	28401	0.11
chr21_36250882_36251033	0.11	RUNX1	runt-related transcription factor 1	8523	0.31
chr8_21313579_21313730	0.11	ENSG00000266713	.	37885	0.21
chr10_49816492_49816643	0.11	ARHGAP22	Rho GTPase activating protein 22	3429	0.27
chr1_20959712_20959863	0.11	PINK1	PTEN induced putative kinase 1	161	0.95
chr2_133195967_133196118	0.11	GPR39	G protein-coupled receptor 39	21895	0.19
chr17_56409271_56409708	0.11	MIR142	microRNA 142	380	0.74
chr3_193491368_193491519	0.11	ENSG00000243991	.	32933	0.21
chr9_90115986_90116137	0.11	DAPK1	death-associated protein kinase 1	2141	0.41
chr1_156553418_156553569	0.11	TTC24	tetratricopeptide repeat domain 24	2336	0.14
chr8_97506971_97507442	0.11	SDC2	syndecan 2	970	0.67
chr4_56501418_56501774	0.11	NMU	neuromedin U	830	0.65
chr1_95201035_95201215	0.11	ENSG00000263526	.	10331	0.26
chr16_31342390_31342554	0.11	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	771	0.53
chr19_1131499_1131650	0.11	SBNO2	strawberry notch homolog 2 (Drosophila)	646	0.58
chr9_132090472_132090833	0.11	ENSG00000242281	.	42088	0.14
chr8_125388828_125388979	0.11	TMEM65	transmembrane protein 65	3970	0.28
chr12_54426850_54427001	0.11	HOXC5	homeobox C5	288	0.68
chr5_138474799_138474993	0.11	SIL1	SIL1 nucleotide exchange factor	7449	0.22
chr19_48011511_48011767	0.11	NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	4384	0.15
chr12_56242031_56242182	0.11	MMP19	matrix metallopeptidase 19	5372	0.1
chr12_53342557_53342709	0.11	KRT18	keratin 18	22	0.94
chr9_131903199_131903823	0.11	PPP2R4	protein phosphatase 2A activator, regulatory subunit 4	414	0.76
chr12_122239357_122239755	0.11	RHOF	ras homolog family member F (in filopodia)	973	0.47
chr1_152022964_152023546	0.11	S100A11	S100 calcium binding protein A11	13744	0.14
chr20_25018363_25018514	0.11	ACSS1	acyl-CoA synthetase short-chain family member 1	5099	0.22
chr8_22779071_22779222	0.11	PEBP4	phosphatidylethanolamine-binding protein 4	6275	0.16
chr6_33806569_33806720	0.11	MLN	motilin	34856	0.15
chr9_127056098_127056249	0.11	NEK6	NIMA-related kinase 6	1474	0.4
chr5_109400140_109400292	0.11	AC011366.3	Uncharacterized protein	181333	0.03
chr11_67908129_67908418	0.11	CTD-2655K5.1		11008	0.15
chr20_58586927_58587156	0.11	CDH26	cadherin 26	15592	0.2
chr16_30007199_30007350	0.11	INO80E	INO80 complex subunit E	238	0.53
chr10_63546087_63546274	0.11	RP11-63A2.2		101034	0.07
chr9_127058687_127058838	0.11	NEK6	NIMA-related kinase 6	3502	0.23
chr11_133904571_133904867	0.11	JAM3	junctional adhesion molecule 3	34101	0.17
chr22_35874169_35874336	0.11	RASD2	RASD family, member 2	62663	0.11
chr21_38071422_38071589	0.11	SIM2	single-minded family bHLH transcription factor 2	71	0.97
chr15_41245906_41246096	0.11	CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	403	0.79
chr19_6239081_6239341	0.11	CTC-503J8.4		19957	0.13
chr5_176922042_176922394	0.11	RP11-1334A24.6		222	0.85
chr17_74488583_74488734	0.11	RHBDF2	rhomboid 5 homolog 2 (Drosophila)	578	0.6
chr7_23312941_23313332	0.10	MALSU1	mitochondrial assembly of ribosomal large subunit 1	25683	0.17
chr1_16861633_16861784	0.10	ENSG00000233421	.	989	0.41
chr14_103590026_103590426	0.10	TNFAIP2	tumor necrosis factor, alpha-induced protein 2	428	0.82
chr2_217529680_217529831	0.10	IGFBP2	insulin-like growth factor binding protein 2, 36kDa	4299	0.2
chr22_35937290_35937443	0.10	RASD2	RASD family, member 2	451	0.86
chr2_88901946_88902210	0.10	EIF2AK3	eukaryotic translation initiation factor 2-alpha kinase 3	6703	0.18
chr11_66428802_66428953	0.10	RP11-658F2.8		4630	0.11
chr9_14348782_14348933	0.10	RP11-120J1.1		1538	0.5
chr6_125420749_125420900	0.10	TPD52L1	tumor protein D52-like 1	19371	0.24
chr2_129493191_129493342	0.10	ENSG00000238379	.	290494	0.01
chr17_46020955_46021139	0.10	PNPO	pyridoxamine 5'-phosphate oxidase	2056	0.15
chr1_3511510_3511661	0.10	MEGF6	multiple EGF-like-domains 6	16474	0.13
chr14_105147633_105147901	0.10	ENSG00000265291	.	3681	0.16
chr12_97379822_97380067	0.10	ENSG00000202368	.	6537	0.31
chr5_139154506_139154831	0.10	PSD2	pleckstrin and Sec7 domain containing 2	20738	0.19
chr16_85989408_85989698	0.10	IRF8	interferon regulatory factor 8	41634	0.18
chr9_124398001_124398152	0.10	DAB2IP	DAB2 interacting protein	15797	0.23
chr3_58044055_58044466	0.10	FLNB	filamin B, beta	19796	0.24
chr22_25373670_25373970	0.10	KIAA1671	KIAA1671	25123	0.18
chr19_38517988_38518282	0.10	ENSG00000221258	.	26470	0.15
chr10_112261658_112261918	0.10	DUSP5	dual specificity phosphatase 5	4192	0.22
chr4_157996843_157997211	0.10	GLRB	glycine receptor, beta	182	0.96
chr2_242714597_242714748	0.10	GAL3ST2	galactose-3-O-sulfotransferase 2	1568	0.23
chr16_57418029_57418329	0.10	CX3CL1	chemokine (C-X3-C motif) ligand 1	7295	0.14
chr11_69453616_69453767	0.10	CCND1	cyclin D1	2164	0.35
chr2_227663253_227663404	0.10	IRS1	insulin receptor substrate 1	1147	0.51
chr14_103991038_103991189	0.10	CKB	creatine kinase, brain	1665	0.19
chr20_35990779_35990930	0.10	SRC	v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog	16297	0.23
chr12_53626909_53627429	0.10	RARG	retinoic acid receptor, gamma	405	0.74
chr1_25070262_25070509	0.10	CLIC4	chloride intracellular channel 4	1463	0.44
chr10_29702503_29702654	0.10	PTCHD3P1	patched domain containing 3 pseudogene 1	3406	0.33
chr1_25321403_25321690	0.10	ENSG00000264371	.	28448	0.16
chr9_140329267_140329418	0.10	ENTPD8	ectonucleoside triphosphate diphosphohydrolase 8	3356	0.14
chr20_4666254_4666846	0.10	PRNP	prion protein	332	0.91
chr3_42567586_42567737	0.10	VIPR1-AS1	VIPR1 antisense RNA 1	5893	0.16
chr1_42136653_42136804	0.10	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	29944	0.22
chr13_100073797_100073948	0.10	ENSG00000266207	.	31851	0.16
chr3_129368977_129369267	0.10	TMCC1	transmembrane and coiled-coil domain family 1	6447	0.21
chr1_236444541_236444706	0.10	ERO1LB	ERO1-like beta (S. cerevisiae)	278	0.91
chr17_80846919_80847070	0.10	TBCD	tubulin folding cofactor D	3034	0.26
chr13_100070069_100070311	0.10	ENSG00000266207	.	35533	0.15
chr10_49496390_49496541	0.10	FRMPD2	FERM and PDZ domain containing 2	13524	0.22
chr2_231741597_231741748	0.10	AC012507.3		9543	0.16
chr17_42163716_42163867	0.10	HDAC5	histone deacetylase 5	6764	0.1
chr1_153463963_153464114	0.10	ENSG00000263841	.	9202	0.1
chr14_102974651_102974824	0.10	ANKRD9	ankyrin repeat domain 9	417	0.82
chr9_116383050_116383201	0.10	RGS3	regulator of G-protein signaling 3	27359	0.19
chr3_135915447_135915650	0.10	MSL2	male-specific lethal 2 homolog (Drosophila)	117	0.98
chr8_95961948_95962152	0.10	RP11-347C18.3		215	0.69
chr15_81072143_81072333	0.10	KIAA1199	KIAA1199	526	0.82
chr11_2011512_2011663	0.10	MRPL23-AS1	MRPL23 antisense RNA 1	437	0.77
chr12_123546608_123546759	0.10	PITPNM2	phosphatidylinositol transfer protein, membrane-associated 2	13959	0.16
chr1_204126949_204127100	0.09	ETNK2	ethanolamine kinase 2	5717	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.2	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0003170	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.1	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.0	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.1	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.1	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.1	GO:0051552	flavone metabolic process(GO:0051552)
0.0	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.0	GO:0061037	negative regulation of cartilage development(GO:0061037)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0009732	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0060872	semicircular canal development(GO:0060872)
0.0	0.1	GO:0031000	response to caffeine(GO:0031000)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.0	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.0	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.2	GO:0009084	glutamine family amino acid biosynthetic process(GO:0009084)
0.0	0.0	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.0	GO:0033505	floor plate morphogenesis(GO:0033505)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.0	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.0	GO:0071436	sodium ion export(GO:0071436)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.0	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.0	GO:0060856	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009) establishment of blood-brain barrier(GO:0060856)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.0	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.1	GO:0035058	nonmotile primary cilium assembly(GO:0035058)
0.0	0.0	GO:0061213	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.0	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.0	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.0	GO:0003416	endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.0	GO:0071803	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0051532	NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.1	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0061028	establishment of endothelial barrier(GO:0061028)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	GO:0072487	MSL complex(GO:0072487)
0.1	GO:0005827	polar microtubule(GO:0005827)
0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	GO:0071437	invadopodium(GO:0071437)
0.0	GO:0031904	endosome lumen(GO:0031904)
0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	GO:0005614	interstitial matrix(GO:0005614)
0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.2	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.3	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.1	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.0	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling