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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ZNF350

Z-value: 0.75

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Transcription factors associated with ZNF350

Gene Symbol Gene ID Gene Info
ZNF350
ENSG00000256683.2 zinc finger protein 350

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr19_52490280_52490507ZNF3502840.8543080.694.1e-02Click!
chr19_52489445_52489599ZNF3504010.7707890.383.1e-01Click!
chr19_52489788_52489939ZNF350600.9579960.284.7e-01Click!

Activity of the ZNF350 motif across conditions

Conditions sorted by the z-value of the ZNF350 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr15_79280672_79280844 0.30 RP11-16K12.1
9527
 0.18
chr16_11089953_11090104 0.28 CLEC16A
 C-type lectin domain family 16, member A
 51590
 0.09
chr6_41736234_41736385 0.22 FRS3
 fibroblast growth factor receptor substrate 3
 9610
 0.1
chr9_137349078_137349350 0.21 RXRA
 retinoid X receptor, alpha
 50786
 0.15
chr12_25433175_25433326 0.21 KRAS
 Kirsten rat sarcoma viral oncogene homolog
 29380
 0.18
chr7_100182794_100183059 0.20 LRCH4
 leucine-rich repeats and calponin homology (CH) domain containing 4
 183
 0.83
chr1_201719762_201719984 0.20 NAV1
 neuron navigator 1
 10877
 0.12
chr21_32715120_32715271 0.20 TIAM1
 T-cell lymphoma invasion and metastasis 1
 1399
 0.58
chr5_14146856_14147066 0.20 TRIO
 trio Rho guanine nucleotide exchange factor
 3132
 0.4
chr17_80929713_80929864 0.20 RP11-1197K16.2
6613
 0.21
chr1_113243152_113243493 0.19 RP11-426L16.3
4079
 0.12
chr2_234608672_234608837 0.19 UGT1A6
 UDP glucuronosyltransferase 1 family, polypeptide A6
 6416
 0.1
chr9_124498089_124498240 0.19 DAB2IP
 DAB2 interacting protein
 6900
 0.28
chr11_12863782_12864036 0.18 RP11-47J17.1
6433
 0.2
chr20_62686749_62686900 0.18 RP13-152O15.5
1332
 0.22
chr11_69257205_69257356 0.18 MYEOV
 myeloma overexpressed
 195655
 0.02
chr20_44978896_44979101 0.18 SLC35C2
 solute carrier family 35 (GDP-fucose transporter), member C2
 8147
 0.2
chr2_220326118_220326333 0.18 SPEG
 SPEG complex locus
 118
 0.93
chr2_20795415_20795848 0.17 HS1BP3-IT1
 HS1BP3 intronic transcript 1 (non-protein coding)
 3323
 0.28
chr20_24929872_24930023 0.17 CST7
 cystatin F (leukocystatin)
 81
 0.97
chr15_70669550_70669810 0.17 ENSG00000200216
 .
 184105
 0.03
chr22_39548986_39549210 0.17 CBX7
 chromobox homolog 7
 443
 0.8
chr11_63381470_63381652 0.16 PLA2G16
 phospholipase A2, group XVI
 280
 0.86
chr12_124781019_124781262 0.16 FAM101A
 family with sequence similarity 101, member A
 1071
 0.61
chr9_72659789_72660086 0.16 MAMDC2
 MAM domain containing 2
 1440
 0.51
chr1_184005215_184005387 0.16 COLGALT2
 collagen beta(1-O)galactosyltransferase 2
 1310
 0.52
chr2_217075636_217075933 0.16 AC012513.6
48534
 0.14
chr7_73120336_73120487 0.16 ENSG00000265724
 .
 5236
 0.11
chr3_156806581_156806732 0.16 ENSG00000201778
 .
 64681
 0.09
chr1_182360343_182360566 0.16 GLUL
 glutamate-ammonia ligase
 85
 0.97
chr20_60933838_60933989 0.16 RP11-157P1.5
5844
 0.13
chr19_47407713_47407864 0.16 ARHGAP35
 Rho GTPase activating protein 35
 14145
 0.17
chr2_160013505_160013656 0.16 WDSUB1
 WD repeat, sterile alpha motif and U-box domain containing 1
 129483
 0.05
chr9_99482773_99482924 0.16 ZNF510
 zinc finger protein 510
 57480
 0.13
chr10_131330632_131330830 0.15 AL355531.2
 Uncharacterized protein
 21206
 0.22
chr10_43249103_43249301 0.15 BMS1
 BMS1 ribosome biogenesis factor
 29047
 0.19
chr3_57199098_57199350 0.15 IL17RD
 interleukin 17 receptor D
 179
 0.95
chr1_181014307_181014479 0.15 MR1
 major histocompatibility complex, class I-related
 11254
 0.18
chr15_31494061_31494212 0.15 TRPM1
 transient receptor potential cation channel, subfamily M, member 1
 40660
 0.18
chr1_113244311_113244462 0.15 RHOC
 ras homolog family member C
 3157
 0.13
chr6_166874425_166874576 0.15 RPS6KA2-IT1
 RPS6KA2 intronic transcript 1 (non-protein coding)
 4371
 0.23
chr13_113583857_113584008 0.15 MCF2L
 MCF.2 cell line derived transforming sequence-like
 27423
 0.15
chr11_128774089_128774256 0.14 C11orf45
 chromosome 11 open reading frame 45
 1420
 0.38
chr7_17234854_17235017 0.14 AC003075.4
85992
 0.1
chr4_1037278_1037479 0.14 FGFRL1
 fibroblast growth factor receptor-like 1
 31139
 0.11
chr5_673661_673812 0.14 CTD-2589H19.6
2205
 0.24
chr14_74984739_74984890 0.14 LTBP2
 latent transforming growth factor beta binding protein 2
 8304
 0.16
chr17_55131688_55131839 0.14 AKAP1
 A kinase (PRKA) anchor protein 1
 30690
 0.13
chr14_93043446_93043626 0.14 RIN3
 Ras and Rab interactor 3
 63388
 0.13
chr18_20772119_20772404 0.14 CABLES1
 Cdk5 and Abl enzyme substrate 1
 36472
 0.16
chr9_131936536_131936750 0.14 RP11-247A12.8
1443
 0.27
chr11_66650721_66650872 0.14 PC
 pyruvate carboxylase
 24576
 0.11
chr15_70877190_70877341 0.14 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 117355
 0.06
chr16_11348403_11348570 0.14 SOCS1
 suppressor of cytokine signaling 1
 1550
 0.21
chr2_87901921_87902194 0.14 ENSG00000265507
 .
 27217
 0.24
chr8_37552274_37552425 0.14 ZNF703
 zinc finger protein 703
 920
 0.47
chr1_3620112_3620445 0.13 TP73
 tumor protein p73
 5656
 0.13
chr11_66823005_66823323 0.13 RHOD
 ras homolog family member D
 1125
 0.44
chr3_169939455_169939857 0.13 PRKCI
 protein kinase C, iota
 497
 0.79
chr3_13323123_13323361 0.13 NUP210
 nucleoporin 210kDa
 138567
 0.05
chr19_36359879_36360032 0.13 APLP1
 amyloid beta (A4) precursor-like protein 1
 420
 0.67
chr3_14494260_14494411 0.13 SLC6A6
 solute carrier family 6 (neurotransmitter transporter), member 6
 19415
 0.22
chr1_22236518_22236840 0.13 HSPG2
 heparan sulfate proteoglycan 2
 13876
 0.16
chr10_115827772_115827923 0.13 ADRB1
 adrenoceptor beta 1
 24041
 0.18
chr3_62573282_62573433 0.13 CADPS
 Ca++-dependent secretion activator
 2436
 0.44
chr6_71666612_71666763 0.13 B3GAT2
 beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
 54
 0.99
chr1_54764314_54764483 0.13 RP5-997D24.3
13320
 0.18
chr19_39423223_39423374 0.13 MRPS12
 mitochondrial ribosomal protein S12
 1659
 0.17
chr6_135504457_135504736 0.13 MYB
 v-myb avian myeloblastosis viral oncogene homolog
 1944
 0.33
chr1_154980745_154981008 0.13 ZBTB7B
 zinc finger and BTB domain containing 7B
 5581
 0.08
chr17_7119350_7119780 0.13 ACADVL
 acyl-CoA dehydrogenase, very long chain
 879
 0.26
chr3_56915864_56916077 0.13 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 34529
 0.19
chr17_4693016_4693203 0.13 GLTPD2
 glycolipid transfer protein domain containing 2
 855
 0.36
chr2_73151273_73151429 0.13 EMX1
 empty spiracles homeobox 1
 234
 0.94
chr8_59571402_59571553 0.13 NSMAF
 neutral sphingomyelinase (N-SMase) activation associated factor
 616
 0.76
chr8_31497191_31497379 0.13 NRG1
 neuregulin 1
 14
 0.99
chr4_75858432_75858583 0.13 PARM1
 prostate androgen-regulated mucin-like protein 1
 181
 0.96
chr2_112105742_112105987 0.13 ENSG00000266139
 .
 27196
 0.26
chr5_140887603_140887841 0.13 DIAPH1
 diaphanous-related formin 1
 17992
 0.08
chr1_151483317_151483639 0.13 CGN
 cingulin
 66
 0.95
chr15_91210216_91210381 0.13 RP11-387D10.3
6328
 0.17
chr19_36398732_36398883 0.12 TYROBP
 TYRO protein tyrosine kinase binding protein
 342
 0.75
chr15_59739965_59740116 0.12 FAM81A
 family with sequence similarity 81, member A
 2735
 0.25
chr17_33570615_33570828 0.12 SLFN5
 schlafen family member 5
 613
 0.47
chr2_95941109_95941447 0.12 PROM2
 prominin 2
 1033
 0.58
chr16_73191000_73191151 0.12 C16orf47
 chromosome 16 open reading frame 47
 12729
 0.28
chr4_186065139_186065290 0.12 SLC25A4
 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
 819
 0.63
chr9_139492984_139493135 0.12 ENSG00000252440
 .
 3908
 0.13
chr11_69251734_69251885 0.12 MYEOV
 myeloma overexpressed
 190184
 0.03
chr11_34267398_34267549 0.12 ENSG00000201867
 .
 56752
 0.14
chr17_39940723_39940965 0.12 JUP
 junction plakoglobin
 563
 0.6
chr4_140871909_140872439 0.12 MAML3
 mastermind-like 3 (Drosophila)
 60053
 0.14
chr22_50707294_50707445 0.12 MAPK11
 mitogen-activated protein kinase 11
 1424
 0.21
chr14_100003657_100003808 0.12 CCDC85C
 coiled-coil domain containing 85C
 1307
 0.41
chr1_27917666_27917818 0.12 AHDC1
 AT hook, DNA binding motif, containing 1
 12360
 0.15
chr5_139046723_139047090 0.12 CXXC5
 CXXC finger protein 5
 7766
 0.22
chr17_38698835_38699076 0.12 CCR7
 chemokine (C-C motif) receptor 7
 18310
 0.15
chr5_175970644_175970798 0.12 CDHR2
 cadherin-related family member 2
 1209
 0.33
chr1_153517829_153518044 0.12 S100A4
 S100 calcium binding protein A4
 342
 0.73
chr20_10551784_10551935 0.12 JAG1
 jagged 1
 91295
 0.08
chr6_90836574_90836725 0.12 ENSG00000222078
 .
 125424
 0.05
chr17_79065717_79065990 0.12 BAIAP2
 BAI1-associated protein 2
 5526
 0.12
chr16_55535078_55535229 0.12 LPCAT2
 lysophosphatidylcholine acyltransferase 2
 7757
 0.22
chr9_133641708_133641929 0.12 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 52451
 0.13
chr14_63861661_63861812 0.12 ENSG00000264995
 .
 67988
 0.1
chr15_74248873_74249108 0.12 LOXL1-AS1
 LOXL1 antisense RNA 1
 28401
 0.11
chr21_36250882_36251033 0.11 RUNX1
 runt-related transcription factor 1
 8523
 0.31
chr8_21313579_21313730 0.11 ENSG00000266713
 .
 37885
 0.21
chr10_49816492_49816643 0.11 ARHGAP22
 Rho GTPase activating protein 22
 3429
 0.27
chr1_20959712_20959863 0.11 PINK1
 PTEN induced putative kinase 1
 161
 0.95
chr2_133195967_133196118 0.11 GPR39
 G protein-coupled receptor 39
 21895
 0.19
chr17_56409271_56409708 0.11 MIR142
 microRNA 142
 380
 0.74
chr3_193491368_193491519 0.11 ENSG00000243991
 .
 32933
 0.21
chr9_90115986_90116137 0.11 DAPK1
 death-associated protein kinase 1
 2141
 0.41
chr1_156553418_156553569 0.11 TTC24
 tetratricopeptide repeat domain 24
 2336
 0.14
chr8_97506971_97507442 0.11 SDC2
 syndecan 2
 970
 0.67
chr4_56501418_56501774 0.11 NMU
 neuromedin U
 830
 0.65
chr1_95201035_95201215 0.11 ENSG00000263526
 .
 10331
 0.26
chr16_31342390_31342554 0.11 ITGAM
 integrin, alpha M (complement component 3 receptor 3 subunit)
 771
 0.53
chr19_1131499_1131650 0.11 SBNO2
 strawberry notch homolog 2 (Drosophila)
 646
 0.58
chr9_132090472_132090833 0.11 ENSG00000242281
 .
 42088
 0.14
chr8_125388828_125388979 0.11 TMEM65
 transmembrane protein 65
 3970
 0.28
chr12_54426850_54427001 0.11 HOXC5
 homeobox C5
 288
 0.68
chr5_138474799_138474993 0.11 SIL1
 SIL1 nucleotide exchange factor
 7449
 0.22
chr19_48011511_48011767 0.11 NAPA
 N-ethylmaleimide-sensitive factor attachment protein, alpha
 4384
 0.15
chr12_56242031_56242182 0.11 MMP19
 matrix metallopeptidase 19
 5372
 0.1
chr12_53342557_53342709 0.11 KRT18
 keratin 18
 22
 0.94
chr9_131903199_131903823 0.11 PPP2R4
 protein phosphatase 2A activator, regulatory subunit 4
 414
 0.76
chr12_122239357_122239755 0.11 RHOF
 ras homolog family member F (in filopodia)
 973
 0.47
chr1_152022964_152023546 0.11 S100A11
 S100 calcium binding protein A11
 13744
 0.14
chr20_25018363_25018514 0.11 ACSS1
 acyl-CoA synthetase short-chain family member 1
 5099
 0.22
chr8_22779071_22779222 0.11 PEBP4
 phosphatidylethanolamine-binding protein 4
 6275
 0.16
chr6_33806569_33806720 0.11 MLN
 motilin
 34856
 0.15
chr9_127056098_127056249 0.11 NEK6
 NIMA-related kinase 6
 1474
 0.4
chr5_109400140_109400292 0.11 AC011366.3
 Uncharacterized protein
 181333
 0.03
chr11_67908129_67908418 0.11 CTD-2655K5.1
11008
 0.15
chr20_58586927_58587156 0.11 CDH26
 cadherin 26
 15592
 0.2
chr16_30007199_30007350 0.11 INO80E
 INO80 complex subunit E
 238
 0.53
chr10_63546087_63546274 0.11 RP11-63A2.2
101034
 0.07
chr9_127058687_127058838 0.11 NEK6
 NIMA-related kinase 6
 3502
 0.23
chr11_133904571_133904867 0.11 JAM3
 junctional adhesion molecule 3
 34101
 0.17
chr22_35874169_35874336 0.11 RASD2
 RASD family, member 2
 62663
 0.11
chr21_38071422_38071589 0.11 SIM2
 single-minded family bHLH transcription factor 2
 71
 0.97
chr15_41245906_41246096 0.11 CHAC1
 ChaC, cation transport regulator homolog 1 (E. coli)
 403
 0.79
chr19_6239081_6239341 0.11 CTC-503J8.4
19957
 0.13
chr5_176922042_176922394 0.11 RP11-1334A24.6
222
 0.85
chr17_74488583_74488734 0.11 RHBDF2
 rhomboid 5 homolog 2 (Drosophila)
 578
 0.6
chr7_23312941_23313332 0.10 MALSU1
 mitochondrial assembly of ribosomal large subunit 1
 25683
 0.17
chr1_16861633_16861784 0.10 ENSG00000233421
 .
 989
 0.41
chr14_103590026_103590426 0.10 TNFAIP2
 tumor necrosis factor, alpha-induced protein 2
 428
 0.82
chr2_217529680_217529831 0.10 IGFBP2
 insulin-like growth factor binding protein 2, 36kDa
 4299
 0.2
chr22_35937290_35937443 0.10 RASD2
 RASD family, member 2
 451
 0.86
chr2_88901946_88902210 0.10 EIF2AK3
 eukaryotic translation initiation factor 2-alpha kinase 3
 6703
 0.18
chr11_66428802_66428953 0.10 RP11-658F2.8
4630
 0.11
chr9_14348782_14348933 0.10 RP11-120J1.1
1538
 0.5
chr6_125420749_125420900 0.10 TPD52L1
 tumor protein D52-like 1
 19371
 0.24
chr2_129493191_129493342 0.10 ENSG00000238379
 .
 290494
 0.01
chr17_46020955_46021139 0.10 PNPO
 pyridoxamine 5'-phosphate oxidase
 2056
 0.15
chr1_3511510_3511661 0.10 MEGF6
 multiple EGF-like-domains 6
 16474
 0.13
chr14_105147633_105147901 0.10 ENSG00000265291
 .
 3681
 0.16
chr12_97379822_97380067 0.10 ENSG00000202368
 .
 6537
 0.31
chr5_139154506_139154831 0.10 PSD2
 pleckstrin and Sec7 domain containing 2
 20738
 0.19
chr16_85989408_85989698 0.10 IRF8
 interferon regulatory factor 8
 41634
 0.18
chr9_124398001_124398152 0.10 DAB2IP
 DAB2 interacting protein
 15797
 0.23
chr3_58044055_58044466 0.10 FLNB
 filamin B, beta
 19796
 0.24
chr22_25373670_25373970 0.10 KIAA1671
 KIAA1671
 25123
 0.18
chr19_38517988_38518282 0.10 ENSG00000221258
 .
 26470
 0.15
chr10_112261658_112261918 0.10 DUSP5
 dual specificity phosphatase 5
 4192
 0.22
chr4_157996843_157997211 0.10 GLRB
 glycine receptor, beta
 182
 0.96
chr2_242714597_242714748 0.10 GAL3ST2
 galactose-3-O-sulfotransferase 2
 1568
 0.23
chr16_57418029_57418329 0.10 CX3CL1
 chemokine (C-X3-C motif) ligand 1
 7295
 0.14
chr11_69453616_69453767 0.10 CCND1
 cyclin D1
 2164
 0.35
chr2_227663253_227663404 0.10 IRS1
 insulin receptor substrate 1
 1147
 0.51
chr14_103991038_103991189 0.10 CKB
 creatine kinase, brain
 1665
 0.19
chr20_35990779_35990930 0.10 SRC
 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
 16297
 0.23
chr12_53626909_53627429 0.10 RARG
 retinoic acid receptor, gamma
 405
 0.74
chr1_25070262_25070509 0.10 CLIC4
 chloride intracellular channel 4
 1463
 0.44
chr10_29702503_29702654 0.10 PTCHD3P1
 patched domain containing 3 pseudogene 1
 3406
 0.33
chr1_25321403_25321690 0.10 ENSG00000264371
 .
 28448
 0.16
chr9_140329267_140329418 0.10 ENTPD8
 ectonucleoside triphosphate diphosphohydrolase 8
 3356
 0.14
chr20_4666254_4666846 0.10 PRNP
 prion protein
 332
 0.91
chr3_42567586_42567737 0.10 VIPR1-AS1
 VIPR1 antisense RNA 1
 5893
 0.16
chr1_42136653_42136804 0.10 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 29944
 0.22
chr13_100073797_100073948 0.10 ENSG00000266207
 .
 31851
 0.16
chr3_129368977_129369267 0.10 TMCC1
 transmembrane and coiled-coil domain family 1
 6447
 0.21
chr1_236444541_236444706 0.10 ERO1LB
 ERO1-like beta (S. cerevisiae)
 278
 0.91
chr17_80846919_80847070 0.10 TBCD
 tubulin folding cofactor D
 3034
 0.26
chr13_100070069_100070311 0.10 ENSG00000266207
 .
 35533
 0.15
chr10_49496390_49496541 0.10 FRMPD2
 FERM and PDZ domain containing 2
 13524
 0.22
chr2_231741597_231741748 0.10 AC012507.3
9543
 0.16
chr17_42163716_42163867 0.10 HDAC5
 histone deacetylase 5
 6764
 0.1
chr1_153463963_153464114 0.10 ENSG00000263841
 .
 9202
 0.1
chr14_102974651_102974824 0.10 ANKRD9
 ankyrin repeat domain 9
 417
 0.82
chr9_116383050_116383201 0.10 RGS3
 regulator of G-protein signaling 3
 27359
 0.19
chr3_135915447_135915650 0.10 MSL2
 male-specific lethal 2 homolog (Drosophila)
 117
 0.98
chr8_95961948_95962152 0.10 RP11-347C18.3
215
 0.69
chr15_81072143_81072333 0.10 KIAA1199
 KIAA1199
 526
 0.82
chr11_2011512_2011663 0.10 MRPL23-AS1
 MRPL23 antisense RNA 1
 437
 0.77
chr12_123546608_123546759 0.10 PITPNM2
 phosphatidylinositol transfer protein, membrane-associated 2
 13959
 0.16
chr1_204126949_204127100 0.09 ETNK2
 ethanolamine kinase 2
 5717
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF350

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.2 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.0 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0003170 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.1 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0010225 response to UV-C(GO:0010225)
0.0 0.0 GO:0061037 negative regulation of cartilage development(GO:0061037)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0060872 semicircular canal development(GO:0060872)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.0 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.2 GO:0009084 glutamine family amino acid biosynthetic process(GO:0009084)
0.0 0.0 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.0 GO:0033505 floor plate morphogenesis(GO:0033505)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.0 GO:0060068 vagina development(GO:0060068)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0060856 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009) establishment of blood-brain barrier(GO:0060856)
0.0 0.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.1 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.0 GO:0061213 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.0 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.0 GO:0003416 endochondral bone growth(GO:0003416) growth plate cartilage development(GO:0003417) bone growth(GO:0098868)
0.0 0.0 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.0 GO:0071803 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0051532 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0061028 establishment of endothelial barrier(GO:0061028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.2 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.0 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.0 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling