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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ZNF423

Z-value: 1.27

Motif logo

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Transcription factors associated with ZNF423

Gene Symbol Gene ID Gene Info
ZNF423
ENSG00000102935.7 zinc finger protein 423

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr16_49890174_49890551ZNF4233160.9230610.863.0e-03Click!
chr16_49891743_49892055ZNF423690.9814760.752.0e-02Click!
chr16_49892831_49893014ZNF42310920.6010790.732.4e-02Click!
chr16_49683940_49684091ZNF42392520.251366-0.732.5e-02Click!
chr16_49892506_49892687ZNF4237660.7284540.713.1e-02Click!

Activity of the ZNF423 motif across conditions

Conditions sorted by the z-value of the ZNF423 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_25886127_25886448 0.73 LDLRAP1
 low density lipoprotein receptor adaptor protein 1
 16216
 0.19
chr16_68109101_68109477 0.70 NFATC3
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
 9958
 0.1
chr16_89521002_89521377 0.65 ENSG00000252887
 .
 11463
 0.12
chr19_19737216_19737375 0.60 LPAR2
 lysophosphatidic acid receptor 2
 1314
 0.3
chr16_85481767_85482285 0.59 ENSG00000264203
 .
 6928
 0.27
chr1_117303582_117303773 0.55 CD2
 CD2 molecule
 6588
 0.23
chr5_133440168_133440408 0.55 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 10114
 0.23
chr17_45277609_45277834 0.52 MYL4
 myosin, light chain 4, alkali; atrial, embryonic
 8680
 0.12
chr16_31477943_31478110 0.51 TGFB1I1
 transforming growth factor beta 1 induced transcript 1
 4880
 0.1
chr9_130473685_130473878 0.50 C9orf117
 chromosome 9 open reading frame 117
 388
 0.73
chr15_44969737_44969888 0.50 PATL2
 protein associated with topoisomerase II homolog 2 (yeast)
 726
 0.6
chr14_99673860_99674011 0.49 AL162151.4
49182
 0.14
chr6_20206050_20206262 0.49 RP11-239H6.2
6162
 0.24
chr11_75220135_75220483 0.47 RP11-939C17.4
873
 0.54
chr2_28647839_28647990 0.46 RP11-373D23.2
28232
 0.14
chr14_94422859_94423119 0.46 ASB2
 ankyrin repeat and SOCS box containing 2
 778
 0.58
chr2_173090506_173090657 0.46 ENSG00000238572
 .
 69733
 0.11
chr4_153033286_153033437 0.46 ENSG00000266244
 .
 116259
 0.06
chr17_75842366_75842622 0.46 FLJ45079
36165
 0.19
chr20_61639034_61639185 0.46 BHLHE23
 basic helix-loop-helix family, member e23
 722
 0.67
chr22_19585555_19585986 0.44 CLDN5
 claudin 5
 70702
 0.08
chr1_9776346_9776497 0.44 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 1706
 0.34
chr1_25345075_25345361 0.44 ENSG00000264371
 .
 4776
 0.25
chr21_43579719_43579870 0.44 ABCG1
 ATP-binding cassette, sub-family G (WHITE), member 1
 40005
 0.13
chr16_89762519_89762771 0.42 SPATA2L
 spermatogenesis associated 2-like
 5403
 0.1
chr3_51718621_51718776 0.42 ENSG00000201595
 .
 9900
 0.15
chr22_46769711_46769909 0.42 TRMU
 tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
 37991
 0.15
chr2_235333773_235334004 0.41 ARL4C
 ADP-ribosylation factor-like 4C
 71356
 0.13
chr14_91832903_91833121 0.41 ENSG00000265856
 .
 32955
 0.17
chr14_105662119_105662372 0.40 NUDT14
 nudix (nucleoside diphosphate linked moiety X)-type motif 14
 14605
 0.15
chr19_54609905_54610056 0.40 NDUFA3
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
 708
 0.42
chr3_169583062_169583383 0.40 LRRC31
 leucine rich repeat containing 31
 4399
 0.16
chr17_37832739_37832926 0.40 PNMT
 phenylethanolamine N-methyltransferase
 8116
 0.1
chr22_31289621_31289772 0.39 OSBP2
 oxysterol binding protein 2
 468
 0.8
chr5_9544937_9545108 0.39 SEMA5A
 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
 1165
 0.47
chr4_2792015_2792228 0.39 SH3BP2
 SH3-domain binding protein 2
 2629
 0.29
chr5_67579614_67579808 0.39 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 3576
 0.36
chr1_777188_777339 0.39 RP11-206L10.8
31722
 0.11
chr1_200856866_200857017 0.39 C1orf106
 chromosome 1 open reading frame 106
 3235
 0.23
chr19_54378263_54378435 0.39 AC008440.5
954
 0.29
chr4_2836679_2837097 0.39 ADD1
 adducin 1 (alpha)
 8696
 0.19
chr11_68597072_68597223 0.39 CPT1A
 carnitine palmitoyltransferase 1A (liver)
 10005
 0.2
chr15_69101431_69101582 0.38 ENSG00000265195
 .
 7242
 0.23
chr1_117453586_117453737 0.38 PTGFRN
 prostaglandin F2 receptor inhibitor
 982
 0.54
chr2_70336914_70337228 0.38 PCBP1-AS1
 PCBP1 antisense RNA 1
 21093
 0.14
chr12_108963200_108963590 0.38 ISCU
 iron-sulfur cluster assembly enzyme
 7009
 0.15
chr9_134127671_134127998 0.37 FAM78A
 family with sequence similarity 78, member A
 18046
 0.15
chr19_30160205_30160356 0.37 PLEKHF1
 pleckstrin homology domain containing, family F (with FYVE domain) member 1
 2499
 0.33
chr1_92931900_92932072 0.37 GFI1
 growth factor independent 1 transcription repressor
 17525
 0.23
chr1_203291434_203291646 0.37 ENSG00000202300
 .
 3313
 0.22
chr8_134508972_134509123 0.37 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 2557
 0.42
chr6_167505175_167505326 0.37 CCR6
 chemokine (C-C motif) receptor 6
 20045
 0.18
chr10_30985837_30986131 0.37 SVILP1
 supervillin pseudogene 1
 1134
 0.61
chr2_46118370_46118521 0.37 PRKCE
 protein kinase C, epsilon
 109596
 0.07
chr11_62408838_62409025 0.37 GANAB
 glucosidase, alpha; neutral AB
 5150
 0.06
chr6_15318009_15318227 0.37 ENSG00000201367
 .
 2967
 0.27
chr1_42271688_42271993 0.36 ENSG00000264896
 .
 47028
 0.18
chr20_62475435_62475724 0.36 AL158091.1
 Protein LOC100509861
 306
 0.78
chr12_123571415_123571566 0.36 PITPNM2
 phosphatidylinositol transfer protein, membrane-associated 2
 5610
 0.2
chr2_127976471_127976630 0.35 CYP27C1
 cytochrome P450, family 27, subfamily C, polypeptide 1
 1104
 0.58
chr21_46900861_46901012 0.35 COL18A1
 collagen, type XVIII, alpha 1
 9253
 0.2
chr10_12589202_12589377 0.35 ENSG00000263584
 .
 31463
 0.2
chr1_1105743_1105894 0.35 ENSG00000198976
 .
 1433
 0.19
chr17_45780207_45780358 0.34 TBKBP1
 TBK1 binding protein 1
 7652
 0.14
chr1_234306113_234306370 0.34 SLC35F3
 solute carrier family 35, member F3
 43776
 0.14
chrX_128902828_128903127 0.34 SASH3
 SAM and SH3 domain containing 3
 10983
 0.19
chr9_92445291_92445531 0.34 GADD45G
 growth arrest and DNA-damage-inducible, gamma
 225458
 0.02
chr1_42106059_42106288 0.34 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 60499
 0.13
chr9_92111235_92111454 0.34 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 1003
 0.5
chr1_167656783_167656934 0.34 MPZL1
 myelin protein zero-like 1
 34329
 0.16
chr4_1617642_1617793 0.33 FAM53A
 family with sequence similarity 53, member A
 39418
 0.14
chr5_169687872_169688139 0.33 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 6295
 0.24
chr16_88770397_88770548 0.33 RNF166
 ring finger protein 166
 447
 0.59
chr7_20370436_20370587 0.33 ITGB8
 integrin, beta 8
 186
 0.88
chr1_54844897_54845115 0.33 SSBP3
 single stranded DNA binding protein 3
 26171
 0.19
chr9_107877201_107877485 0.33 ENSG00000201583
 .
 18306
 0.27
chr11_65385759_65385910 0.33 PCNXL3
 pecanex-like 3 (Drosophila)
 2590
 0.11
chr1_112020736_112021030 0.33 C1orf162
 chromosome 1 open reading frame 162
 4392
 0.12
chr9_134458873_134459024 0.33 RAPGEF1
 Rap guanine nucleotide exchange factor (GEF) 1
 38277
 0.13
chr21_45334011_45334235 0.33 AGPAT3
 1-acylglycerol-3-phosphate O-acyltransferase 3
 2030
 0.3
chr17_72459036_72459537 0.33 CD300A
 CD300a molecule
 3269
 0.19
chr11_117821389_117821783 0.33 TMPRSS13
 transmembrane protease, serine 13
 21412
 0.15
chr6_158993933_158994198 0.33 TMEM181
 transmembrane protein 181
 36597
 0.15
chr7_138777169_138777799 0.32 ZC3HAV1
 zinc finger CCCH-type, antiviral 1
 13471
 0.2
chr9_95825508_95825700 0.32 SUSD3
 sushi domain containing 3
 4543
 0.2
chr11_1606465_1606821 0.32 KRTAP5-1
 keratin associated protein 5-1
 130
 0.93
chr3_187767301_187767602 0.32 LPP
 LIM domain containing preferred translocation partner in lipoma
 103621
 0.07
chr10_29776432_29776729 0.32 SVIL
 supervillin
 8867
 0.24
chr22_30693041_30693254 0.32 RP1-130H16.18
 Uncharacterized protein
 2324
 0.16
chr14_98459359_98459510 0.32 C14orf64
 chromosome 14 open reading frame 64
 14973
 0.31
chr15_70825685_70825836 0.32 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 168860
 0.04
chr1_167570557_167570959 0.32 RCSD1
 RCSD domain containing 1
 28572
 0.15
chr8_128994096_128994247 0.32 ENSG00000207110
 .
 17206
 0.16
chr20_1677648_1677799 0.32 ENSG00000242348
 .
 30717
 0.14
chr6_125666901_125667052 0.32 RP11-735G4.1
28494
 0.21
chr7_102072492_102072712 0.32 ORAI2
 ORAI calcium release-activated calcium modulator 2
 951
 0.34
chr2_99077021_99077380 0.32 INPP4A
 inositol polyphosphate-4-phosphatase, type I, 107kDa
 15787
 0.23
chr5_154193336_154193487 0.31 LARP1
 La ribonucleoprotein domain family, member 1
 9630
 0.16
chr21_19152626_19152837 0.31 AL109761.5
13074
 0.23
chr8_97165985_97166258 0.31 GDF6
 growth differentiation factor 6
 6899
 0.26
chr17_73234704_73234855 0.31 GGA3
 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
 287
 0.81
chr9_36143975_36144155 0.31 GLIPR2
 GLI pathogenesis-related 2
 7323
 0.19
chr1_2426510_2426661 0.31 RP3-395M20.3
667
 0.51
chr6_24866477_24866656 0.31 FAM65B
 family with sequence similarity 65, member B
 10975
 0.19
chr1_204450638_204450997 0.31 PIK3C2B
 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
 8629
 0.19
chr20_39774881_39775244 0.31 RP1-1J6.2
8419
 0.2
chr17_76115212_76115363 0.30 TMC6
 transmembrane channel-like 6
 3542
 0.15
chr22_29215628_29215779 0.30 CTA-292E10.6
1384
 0.35
chr1_118195260_118195411 0.30 ENSG00000212266
 .
 36029
 0.17
chr1_183440737_183440894 0.30 SMG7
 SMG7 nonsense mediated mRNA decay factor
 691
 0.73
chr20_47239118_47239269 0.30 ENSG00000238452
 .
 116638
 0.06
chr7_4792903_4793054 0.30 FOXK1
 forkhead box K1
 12488
 0.16
chr19_42398087_42398358 0.30 ARHGEF1
 Rho guanine nucleotide exchange factor (GEF) 1
 143
 0.93
chr15_29382386_29382685 0.30 APBA2
 amyloid beta (A4) precursor protein-binding, family A, member 2
 46008
 0.17
chr10_135076415_135076765 0.30 ADAM8
 ADAM metallopeptidase domain 8
 13764
 0.09
chr20_55975873_55976024 0.30 RP4-800J21.3
7830
 0.16
chr17_45782038_45782291 0.30 TBKBP1
 TBK1 binding protein 1
 9534
 0.13
chr18_21200887_21201038 0.30 ANKRD29
 ankyrin repeat domain 29
 28524
 0.15
chr14_101109543_101109694 0.30 CTD-2644I21.1
53955
 0.07
chr9_127120006_127120171 0.30 ENSG00000264237
 .
 7278
 0.21
chr7_1104722_1104898 0.29 RP11-449P15.1
5913
 0.1
chr7_49814485_49814636 0.29 VWC2
 von Willebrand factor C domain containing 2
 1303
 0.63
chr16_67795135_67795286 0.29 RP11-167P11.2
21385
 0.1
chr21_46333137_46333552 0.29 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 854
 0.44
chr5_176802584_176802735 0.29 SLC34A1
 solute carrier family 34 (type II sodium/phosphate contransporter), member 1
 3577
 0.12
chr14_91849387_91849607 0.29 CCDC88C
 coiled-coil domain containing 88C
 34193
 0.17
chr6_139494692_139494843 0.29 HECA
 headcase homolog (Drosophila)
 38518
 0.17
chr15_81588541_81588692 0.28 IL16
 interleukin 16
 638
 0.74
chr22_37812190_37812341 0.28 RP1-63G5.5
11215
 0.14
chr5_169706251_169706453 0.28 LCP2
 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
 12021
 0.22
chr11_63305751_63305902 0.28 RARRES3
 retinoic acid receptor responder (tazarotene induced) 3
 42
 0.97
chr6_33663289_33663440 0.28 SBP1
 SBP1; Uncharacterized protein
 110
 0.95
chr20_50143060_50143387 0.28 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 16035
 0.26
chr1_12245359_12245510 0.28 ENSG00000263676
 .
 6336
 0.17
chr19_50923202_50923353 0.28 SPIB
 Spi-B transcription factor (Spi-1/PU.1 related)
 1062
 0.3
chr11_6742431_6742729 0.28 GVINP1
 GTPase, very large interferon inducible pseudogene 1
 531
 0.69
chr14_100850226_100850465 0.28 WDR25
 WD repeat domain 25
 2008
 0.19
chr7_142045834_142045985 0.28 PRSS3P3
 protease, serine, 3 pseudogene 3
 56300
 0.13
chr11_74983514_74983728 0.27 ARRB1
 arrestin, beta 1
 6122
 0.14
chr4_1797283_1797487 0.27 FGFR3
 fibroblast growth factor receptor 3
 1762
 0.33
chr20_62104787_62104938 0.27 KCNQ2
 potassium voltage-gated channel, KQT-like subfamily, member 2
 869
 0.46
chr20_37435383_37435534 0.27 PPP1R16B
 protein phosphatase 1, regulatory subunit 16B
 1091
 0.52
chr2_95716411_95716700 0.27 AC103563.9
2366
 0.25
chr20_62488359_62488510 0.27 ABHD16B
 abhydrolase domain containing 16B
 4132
 0.09
chr17_1199306_1199457 0.27 TUSC5
 tumor suppressor candidate 5
 16424
 0.17
chr2_99449405_99449556 0.27 ENSG00000238830
 .
 7719
 0.22
chr15_70545445_70545596 0.27 ENSG00000200216
 .
 59945
 0.15
chr11_67177814_67178291 0.27 CARNS1
 carnosine synthase 1
 5097
 0.07
chr3_18684786_18684937 0.27 ENSG00000228956
 .
 50518
 0.19
chr2_238813522_238813924 0.27 ENSG00000263723
 .
 35176
 0.15
chr1_154932014_154932227 0.27 PYGO2
 pygopus family PHD finger 2
 2104
 0.12
chr4_2838265_2838548 0.27 ADD1
 adducin 1 (alpha)
 7178
 0.2
chr11_67201895_67202105 0.27 AP003419.16
870
 0.3
chr17_77904427_77904652 0.26 TBC1D16
 TBC1 domain family, member 16
 20088
 0.18
chr13_53277825_53277976 0.26 LECT1
 leukocyte cell derived chemotaxin 1
 35587
 0.16
chr17_72474398_72474597 0.26 CD300A
 CD300a molecule
 11496
 0.14
chr2_74228872_74229028 0.26 TET3
 tet methylcytosine dioxygenase 3
 890
 0.55
chr13_111948297_111948901 0.26 TEX29
 testis expressed 29
 24416
 0.22
chr3_15319690_15320104 0.26 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 2345
 0.23
chr11_441488_441639 0.26 ANO9
 anoctamin 9
 448
 0.56
chr22_42592642_42592793 0.26 TCF20
 transcription factor 20 (AR1)
 13497
 0.16
chr1_207095862_207096179 0.26 FAIM3
 Fas apoptotic inhibitory molecule 3
 521
 0.73
chr19_3024526_3024677 0.26 TLE2
 transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
 424
 0.77
chr16_88535878_88536112 0.26 ENSG00000263456
 .
 669
 0.68
chr17_43310695_43311082 0.26 FMNL1
 formin-like 1
 7554
 0.1
chr19_4088417_4088592 0.26 MAP2K2
 mitogen-activated protein kinase kinase 2
 12541
 0.11
chr17_73150023_73150174 0.25 HN1
 hematological and neurological expressed 1
 137
 0.91
chr10_82339230_82339422 0.25 SH2D4B
 SH2 domain containing 4B
 38751
 0.17
chr2_106429372_106429523 0.25 NCK2
 NCK adaptor protein 2
 3568
 0.32
chr19_50064241_50064618 0.25 NOSIP
 nitric oxide synthase interacting protein
 481
 0.57
chr9_92063731_92064015 0.25 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 6995
 0.26
chr11_128555736_128555887 0.25 RP11-744N12.3
512
 0.52
chr9_136351101_136351399 0.25 SLC2A6
 solute carrier family 2 (facilitated glucose transporter), member 6
 6991
 0.12
chr12_12418765_12419238 0.25 LRP6
 low density lipoprotein receptor-related protein 6
 702
 0.68
chr22_44890267_44890418 0.25 LDOC1L
 leucine zipper, down-regulated in cancer 1-like
 3836
 0.34
chr4_54959914_54960069 0.25 GSX2
 GS homeobox 2
 6207
 0.17
chr11_2860656_2860807 0.25 KCNQ1-AS1
 KCNQ1 antisense RNA 1
 22067
 0.13
chr19_4064720_4064871 0.25 ZBTB7A
 zinc finger and BTB domain containing 7A
 935
 0.4
chr12_133100245_133100396 0.25 FBRSL1
 fibrosin-like 1
 33163
 0.16
chr13_99176253_99176430 0.25 STK24
 serine/threonine kinase 24
 2089
 0.37
chr3_13057227_13057378 0.25 IQSEC1
 IQ motif and Sec7 domain 1
 28766
 0.23
chr2_27530014_27530299 0.25 UCN
 urocortin
 1157
 0.27
chr7_75367789_75368030 0.25 HIP1
 huntingtin interacting protein 1
 350
 0.89
chr1_214460978_214461129 0.25 SMYD2
 SET and MYND domain containing 2
 6477
 0.3
chr22_50754075_50754226 0.25 XX-C283C717.1
1090
 0.31
chr19_12550187_12550350 0.24 CTD-3105H18.16
 Uncharacterized protein
 1628
 0.22
chrX_46488224_46488448 0.24 CHST7
 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
 55117
 0.14
chr17_8533635_8533853 0.24 MYH10
 myosin, heavy chain 10, non-muscle
 291
 0.92
chr12_104350569_104350720 0.24 C12orf73
 chromosome 12 open reading frame 73
 281
 0.87
chr17_48988068_48988440 0.24 TOB1
 transducer of ERBB2, 1
 42915
 0.11
chr1_9776061_9776212 0.24 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 1991
 0.31
chr21_46741518_46741669 0.24 ENSG00000215447
 .
 33626
 0.13
chr3_13277082_13277233 0.24 IQSEC1
 IQ motif and Sec7 domain 1
 162540
 0.04
chr20_61424831_61424989 0.24 MRGBP
 MRG/MORF4L binding protein
 2895
 0.16
chr1_151793784_151793935 0.24 RORC
 RAR-related orphan receptor C
 4708
 0.09
chr22_27067872_27068143 0.24 CRYBA4
 crystallin, beta A4
 50079
 0.13
chr19_7741444_7741683 0.24 C19orf59
 chromosome 19 open reading frame 59
 49
 0.93
chr7_151078058_151078311 0.24 NUB1
 negative regulator of ubiquitin-like proteins 1
 12268
 0.13
chr13_114875590_114875798 0.24 RASA3-IT1
 RASA3 intronic transcript 1 (non-protein coding)
 1399
 0.48
chr2_242800699_242800986 0.24 PDCD1
 programmed cell death 1
 218
 0.89

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF423

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.1 0.2 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.1 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.1 GO:0009191 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.2 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.2 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.2 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.3 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.2 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.2 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.3 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0014808 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0 0.2 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) positive regulation of cell cycle G1/S phase transition(GO:1902808)
0.0 0.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.0 GO:0070266 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0032769 negative regulation of monooxygenase activity(GO:0032769)
0.0 0.8 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.1 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.1 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.2 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.2 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.1 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0061054 dermatome development(GO:0061054)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.0 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.1 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.0 GO:0002724 regulation of T cell cytokine production(GO:0002724)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.4 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.0 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0010039 response to iron ion(GO:0010039)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.1 GO:0034626 fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.0 GO:0032610 interleukin-1 alpha production(GO:0032610) regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.0 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.0 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0001967 suckling behavior(GO:0001967)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.0 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.0 GO:0031558 obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.0 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.0 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.0 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.7 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.3 GO:0035303 regulation of dephosphorylation(GO:0035303)
0.0 0.1 GO:0032967 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.0 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 0.1 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.1 GO:0016556 mRNA modification(GO:0016556)
0.0 0.1 GO:0002209 behavioral defense response(GO:0002209)
0.0 0.1 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.0 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.1 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.0 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.0 GO:0090185 negative regulation of kidney development(GO:0090185)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.0 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.0 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0001961 positive regulation of cytokine-mediated signaling pathway(GO:0001961)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.0 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.2 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.1 GO:0042640 anagen(GO:0042640)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.1 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0000791 euchromatin(GO:0000791)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288) cell envelope(GO:0030313) periplasmic space(GO:0042597)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.2 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.0 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)