Project
ENCODE: H3K4me1 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for ZNF691

Z-value: 1.62

Motif logo

logo of

Transcription factors associated with ZNF691

Gene Symbol Gene ID Gene Info
ZNF691
ENSG00000164011.13 zinc finger protein 691

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_43312662_43313245ZNF6916450.467785-0.589.9e-02Click!
chr1_43313270_43313437ZNF69110450.342245-0.432.5e-01Click!
chr1_43313653_43313900ZNF69111860.3294680.353.6e-01Click!

Activity of the ZNF691 motif across conditions

Conditions sorted by the z-value of the ZNF691 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr15_78339069_78339553 0.67 ENSG00000221476
 .
 8438
 0.14
chr3_186237166_186237573 0.63 CRYGS
 crystallin, gamma S
 24871
 0.16
chrX_68051276_68051467 0.63 EFNB1
 ephrin-B1
 2531
 0.43
chr1_17386538_17387050 0.61 SDHB
 succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
 6129
 0.19
chr9_130788882_130789033 0.60 RP11-379C10.1
30684
 0.08
chr12_5996760_5996911 0.58 ANO2
 anoctamin 2
 58563
 0.15
chr1_167598142_167598391 0.58 RCSD1
 RCSD domain containing 1
 1064
 0.46
chr10_111975212_111975532 0.57 MXI1
 MAX interactor 1, dimerization protein
 5383
 0.23
chr10_73505279_73505456 0.57 C10orf105
 chromosome 10 open reading frame 105
 7786
 0.2
chr11_307203_307402 0.53 IFITM2
 interferon induced transmembrane protein 2
 329
 0.7
chr7_73634593_73634808 0.53 LAT2
 linker for activation of T cells family, member 2
 10347
 0.15
chr11_64976530_64976899 0.53 CAPN1
 calpain 1, (mu/I) large subunit
 25907
 0.08
chr12_105085856_105086193 0.52 ENSG00000264295
 .
 100613
 0.07
chr8_68881201_68881427 0.52 PREX2
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
 16961
 0.28
chr2_8618267_8618671 0.52 AC011747.7
197427
 0.03
chr15_70012041_70012192 0.51 ENSG00000238870
 .
 11045
 0.27
chr17_73309208_73309370 0.51 GRB2
 growth factor receptor-bound protein 2
 8545
 0.1
chr2_68998735_68999008 0.51 ARHGAP25
 Rho GTPase activating protein 25
 3062
 0.32
chr7_36817273_36817729 0.50 AOAH
 acyloxyacyl hydrolase (neutrophil)
 53347
 0.14
chr15_64101453_64101862 0.49 HERC1
 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
 24427
 0.21
chr12_26625611_26625802 0.49 ENSG00000212549
 .
 99040
 0.07
chr9_132708644_132709361 0.49 RP11-409K20.6
13187
 0.19
chr6_164087851_164088077 0.49 QKI
 QKI, KH domain containing, RNA binding
 131852
 0.06
chr7_114660359_114660758 0.49 MDFIC
 MyoD family inhibitor domain containing
 86634
 0.1
chr17_79421737_79422000 0.48 ENSG00000266189
 .
 3654
 0.13
chr6_170404847_170405519 0.47 RP11-302L19.1
72558
 0.11
chr17_10019598_10019977 0.47 GAS7
 growth arrest-specific 7
 1917
 0.36
chr14_22695045_22695275 0.46 ENSG00000238634
 .
 84273
 0.09
chr9_101872557_101872836 0.46 TGFBR1
 transforming growth factor, beta receptor 1
 5264
 0.24
chr2_103036334_103036659 0.46 IL18RAP
 interleukin 18 receptor accessory protein
 350
 0.84
chr6_137545479_137545658 0.45 IFNGR1
 interferon gamma receptor 1
 4982
 0.29
chr18_60607220_60607410 0.45 PHLPP1
 PH domain and leucine rich repeat protein phosphatase 1
 36932
 0.19
chr13_24826926_24827157 0.45 SPATA13
 spermatogenesis associated 13
 1185
 0.38
chr1_116707962_116708157 0.45 MAB21L3
 mab-21-like 3 (C. elegans)
 53683
 0.15
chr2_145139248_145139576 0.45 ZEB2
 zinc finger E-box binding homeobox 2
 48181
 0.16
chr6_159477497_159477912 0.45 TAGAP
 T-cell activation RhoGTPase activating protein
 11520
 0.2
chr2_198078183_198078504 0.44 ANKRD44
 ankyrin repeat domain 44
 15581
 0.19
chr1_235097341_235097798 0.44 ENSG00000239690
 .
 57636
 0.14
chr16_84631220_84631677 0.44 RP11-61F12.1
3449
 0.22
chr3_51602527_51602730 0.44 RAD54L2
 RAD54-like 2 (S. cerevisiae)
 27032
 0.16
chr11_326229_326864 0.44 IFITM3
 interferon induced transmembrane protein 3
 991
 0.28
chr2_231523692_231523963 0.44 CAB39
 calcium binding protein 39
 53733
 0.12
chr6_41048495_41048843 0.43 NFYA
 nuclear transcription factor Y, alpha
 7947
 0.13
chr2_16805738_16806019 0.43 FAM49A
 family with sequence similarity 49, member A
 1534
 0.56
chr17_1100373_1100524 0.43 ABR
 active BCR-related
 9832
 0.19
chr12_6569203_6569458 0.43 TAPBPL
 TAP binding protein-like
 8080
 0.09
chrX_37655630_37655781 0.42 CYBB
 cytochrome b-245, beta polypeptide
 16388
 0.22
chr2_46612633_46612855 0.42 ENSG00000241791
 .
 62906
 0.11
chr17_56381480_56381712 0.42 BZRAP1
 benzodiazepine receptor (peripheral) associated protein 1
 2122
 0.2
chr1_198628339_198628592 0.42 RP11-553K8.5
7725
 0.25
chr8_141061304_141061455 0.42 C8orf17
 chromosome 8 open reading frame 17
 117963
 0.06
chr3_187546263_187546452 0.41 BCL6
 B-cell CLL/lymphoma 6
 82842
 0.1
chr11_65321440_65321876 0.41 LTBP3
 latent transforming growth factor beta binding protein 3
 460
 0.63
chr2_231508120_231508337 0.41 ENSG00000199791
 .
 56392
 0.11
chr3_72356860_72357126 0.41 ENSG00000212070
 .
 45414
 0.19
chr17_4617996_4618234 0.41 ARRB2
 arrestin, beta 2
 769
 0.41
chr12_121212774_121212925 0.41 RP11-173P15.7
13454
 0.13
chr1_234977189_234977340 0.41 ENSG00000201638
 .
 3544
 0.33
chr2_223290050_223290739 0.41 SGPP2
 sphingosine-1-phosphate phosphatase 2
 1158
 0.52
chr18_2970175_2970373 0.41 RP11-737O24.1
3258
 0.2
chr12_4675360_4675724 0.40 DYRK4
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
 4172
 0.2
chr14_61817217_61817623 0.40 PRKCH
 protein kinase C, eta
 2811
 0.3
chr13_115027942_115028247 0.40 ENSG00000265450
 .
 11209
 0.15
chr20_30108617_30108801 0.40 HM13
 histocompatibility (minor) 13
 6385
 0.14
chr3_129672889_129673040 0.40 RP11-93K22.6
15173
 0.16
chr5_1477727_1478025 0.40 SLC6A3
 solute carrier family 6 (neurotransmitter transporter), member 3
 32331
 0.17
chr1_100976278_100976464 0.40 RP5-837M10.4
24818
 0.19
chr8_61829687_61829838 0.39 RP11-33I11.2
107597
 0.07
chr2_68950083_68950336 0.39 ARHGAP25
 Rho GTPase activating protein 25
 11704
 0.25
chr11_64821624_64821914 0.39 NAALADL1
 N-acetylated alpha-linked acidic dipeptidase-like 1
 4224
 0.08
chr2_60639825_60639976 0.39 ENSG00000266078
 .
 25320
 0.19
chr11_36472811_36473244 0.39 RP11-219O3.2
25355
 0.17
chr18_24303751_24303902 0.39 ENSG00000265369
 .
 34333
 0.18
chr19_52139861_52140012 0.38 SIGLEC5
 sialic acid binding Ig-like lectin 5
 6348
 0.11
chr14_90035572_90035859 0.38 FOXN3-AS2
 FOXN3 antisense RNA 2
 6845
 0.18
chr9_136567139_136567359 0.38 SARDH
 sarcosine dehydrogenase
 1574
 0.4
chr9_101899174_101899462 0.38 ENSG00000252942
 .
 8930
 0.19
chr15_43562949_43563145 0.38 TGM5
 transglutaminase 5
 3992
 0.15
chr17_76745970_76746190 0.38 CYTH1
 cytohesin 1
 13108
 0.19
chr10_87622590_87622741 0.38 GRID1
 glutamate receptor, ionotropic, delta 1
 71349
 0.13
chr22_23799086_23799320 0.38 ZDHHC8P1
 zinc finger, DHHC-type containing 8 pseudogene 1
 54859
 0.11
chrX_65207483_65207634 0.38 RP6-159A1.3
12035
 0.22
chrX_30657144_30657355 0.38 GK
 glycerol kinase
 14227
 0.19
chr16_3126499_3126886 0.37 ENSG00000252561
 .
 7168
 0.06
chr2_106393790_106393957 0.37 NCK2
 NCK adaptor protein 2
 31685
 0.22
chr19_49264086_49264354 0.37 FGF21
 fibroblast growth factor 21
 4876
 0.09
chr5_138404014_138404249 0.37 SIL1
 SIL1 nucleotide exchange factor
 25760
 0.17
chr17_71589775_71590041 0.37 RP11-277J6.2
47257
 0.14
chr3_5095854_5096064 0.37 ENSG00000207283
 .
 32005
 0.16
chr6_109642207_109642358 0.37 ENSG00000201023
 .
 15585
 0.17
chr2_30726596_30726829 0.37 LCLAT1
 lysocardiolipin acyltransferase 1
 56443
 0.15
chr3_187767704_187767957 0.37 LPP
 LIM domain containing preferred translocation partner in lipoma
 103242
 0.07
chr13_77388256_77388424 0.37 KCTD12
 potassium channel tetramerization domain containing 12
 72185
 0.11
chr1_161596720_161596871 0.37 FCGR3B
 Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
 4027
 0.14
chr5_157893434_157893585 0.36 ENSG00000222626
 .
 489545
 0.0
chr8_134143385_134143542 0.36 TG
 thyroglobulin
 17716
 0.2
chr7_142014232_142014383 0.36 PRSS3P3
 protease, serine, 3 pseudogene 3
 24698
 0.2
chr20_48505464_48505717 0.36 SPATA2
 spermatogenesis associated 2
 24686
 0.13
chr11_67779011_67779350 0.36 ALDH3B1
 aldehyde dehydrogenase 3 family, member B1
 1390
 0.28
chr6_159474723_159475009 0.36 TAGAP
 T-cell activation RhoGTPase activating protein
 8682
 0.2
chr5_80282965_80283116 0.36 CTC-459I6.1
26314
 0.2
chr4_37953488_37953689 0.36 PTTG2
 pituitary tumor-transforming 2
 8468
 0.25
chr5_77093628_77093984 0.36 TBCA
 tubulin folding cofactor A
 21621
 0.27
chr13_114270534_114270823 0.36 TFDP1
 transcription factor Dp-1
 30937
 0.15
chr8_109683273_109683424 0.36 TMEM74
 transmembrane protein 74
 116496
 0.07
chr11_36422136_36422312 0.36 PRR5L
 proline rich 5 like
 391
 0.86
chr3_148426073_148426436 0.36 AGTR1
 angiotensin II receptor, type 1
 10549
 0.28
chr8_101823524_101823815 0.35 ENSG00000222795
 .
 20419
 0.17
chr3_185313043_185313423 0.35 SENP2
 SUMO1/sentrin/SMT3 specific peptidase 2
 9150
 0.23
chr3_4576803_4576954 0.35 ITPR1
 inositol 1,4,5-trisphosphate receptor, type 1
 18702
 0.22
chr3_13022230_13022381 0.35 IQSEC1
 IQ motif and Sec7 domain 1
 6231
 0.28
chr19_51919928_51920449 0.35 SIGLEC10
 sialic acid binding Ig-like lectin 10
 647
 0.4
chr10_73467882_73468053 0.35 C10orf105
 chromosome 10 open reading frame 105
 11611
 0.22
chr2_102907622_102907872 0.35 IL1RL1
 interleukin 1 receptor-like 1
 20215
 0.18
chr12_77099684_77099835 0.35 ZDHHC17
 zinc finger, DHHC-type containing 17
 57609
 0.15
chr13_34304744_34304895 0.35 RFC3
 replication factor C (activator 1) 3, 38kDa
 87367
 0.09
chr10_90594188_90594339 0.35 ANKRD22
 ankyrin repeat domain 22
 17312
 0.16
chr5_94363992_94364271 0.35 MCTP1
 multiple C2 domains, transmembrane 1
 10940
 0.27
chr7_5517446_5517597 0.35 ENSG00000238394
 .
 7505
 0.13
chr19_50311562_50311736 0.35 FUZ
 fuzzy planar cell polarity protein
 247
 0.66
chr6_41247154_41247420 0.34 TREM1
 triggering receptor expressed on myeloid cells 1
 7116
 0.14
chr2_197114023_197114207 0.34 AC020571.3
10633
 0.19
chr15_55096406_55096557 0.34 UNC13C
 unc-13 homolog C (C. elegans)
 192808
 0.03
chr7_36761018_36761307 0.34 AOAH
 acyloxyacyl hydrolase (neutrophil)
 2892
 0.34
chr10_126416114_126416281 0.34 FAM53B
 family with sequence similarity 53, member B
 15342
 0.16
chrX_149619256_149619532 0.34 MAMLD1
 mastermind-like domain containing 1
 5674
 0.27
chr3_112192770_112193234 0.34 BTLA
 B and T lymphocyte associated
 25203
 0.21
chr3_36936222_36936373 0.34 TRANK1
 tetratricopeptide repeat and ankyrin repeat containing 1
 35923
 0.17
chr13_100072786_100073153 0.34 ENSG00000266207
 .
 32754
 0.16
chr17_14102455_14103001 0.34 AC005224.2
11077
 0.2
chr10_50397490_50397641 0.34 C10orf128
 chromosome 10 open reading frame 128
 1129
 0.52
chr10_99126345_99126553 0.34 RRP12
 ribosomal RNA processing 12 homolog (S. cerevisiae)
 24153
 0.09
chr6_157544607_157544758 0.34 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 74637
 0.11
chr16_85602814_85602967 0.34 GSE1
 Gse1 coiled-coil protein
 42125
 0.15
chr13_40527264_40527478 0.34 ENSG00000212553
 .
 96007
 0.09
chr2_98706356_98706507 0.34 VWA3B
 von Willebrand factor A domain containing 3B
 2732
 0.37
chr14_100681991_100682142 0.34 YY1
 YY1 transcription factor
 22569
 0.11
chr1_6066778_6067032 0.34 KCNAB2
 potassium voltage-gated channel, shaker-related subfamily, beta member 2
 14134
 0.17
chr12_9946895_9947085 0.34 KLRF1
 killer cell lectin-like receptor subfamily F, member 1
 33087
 0.11
chr6_157728804_157729008 0.34 TMEM242
 transmembrane protein 242
 15727
 0.21
chr2_169451192_169451376 0.34 ENSG00000199348
 .
 11722
 0.22
chr17_43305250_43305421 0.33 CTD-2020K17.1
5746
 0.1
chr7_107268887_107269038 0.33 ENSG00000238832
 .
 25154
 0.12
chr11_74170646_74170839 0.33 KCNE3
 potassium voltage-gated channel, Isk-related family, member 3
 2670
 0.19
chr2_234238429_234238580 0.33 SAG
 S-antigen; retina and pineal gland (arrestin)
 10310
 0.14
chr8_116675134_116675411 0.33 TRPS1
 trichorhinophalangeal syndrome I
 1367
 0.61
chr9_111528485_111528636 0.33 ACTL7B
 actin-like 7B
 90679
 0.08
chr3_142926768_142926919 0.33 ENSG00000211483
 .
 42353
 0.17
chr1_153409038_153409284 0.33 S100A7L2
 S100 calcium binding protein A7-like 2
 3264
 0.14
chr1_167682497_167682682 0.33 MPZL1
 myelin protein zero-like 1
 8598
 0.24
chr3_137855166_137855317 0.33 A4GNT
 alpha-1,4-N-acetylglucosaminyltransferase
 4012
 0.22
chr22_17580165_17580321 0.33 IL17RA
 interleukin 17 receptor A
 14394
 0.14
chrX_131168944_131169159 0.32 MST4
 Serine/threonine-protein kinase MST4
 11415
 0.22
chr7_101055237_101055388 0.32 COL26A1
 collagen, type XXVI, alpha 1
 49190
 0.12
chr11_75603352_75603503 0.32 UVRAG
 UV radiation resistance associated
 13979
 0.14
chr2_225758571_225758722 0.32 DOCK10
 dedicator of cytokinesis 10
 53136
 0.18
chr11_128606943_128607372 0.32 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
 27528
 0.17
chr1_111738933_111739395 0.32 DENND2D
 DENN/MADD domain containing 2D
 4147
 0.14
chr20_44688889_44689146 0.32 NCOA5
 nuclear receptor coactivator 5
 29574
 0.11
chr1_153745441_153745734 0.32 SLC27A3
 solute carrier family 27 (fatty acid transporter), member 3
 1243
 0.28
chr1_84901747_84901929 0.32 DNASE2B
 deoxyribonuclease II beta
 27925
 0.16
chr20_36933120_36933276 0.32 BPI
 bactericidal/permeability-increasing protein
 673
 0.65
chr5_34863800_34863951 0.32 CTD-2517O10.6
24492
 0.15
chr7_76982153_76982343 0.32 GSAP
 gamma-secretase activating protein
 22564
 0.22
chr9_80482015_80482166 0.32 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 44175
 0.2
chr7_100930424_100930627 0.32 RP11-132A1.3
12369
 0.11
chr16_50296689_50296840 0.32 ADCY7
 adenylate cyclase 7
 3663
 0.26
chr19_2695525_2695860 0.32 GNG7
 guanine nucleotide binding protein (G protein), gamma 7
 7015
 0.12
chr4_89659336_89659555 0.32 FAM13A-AS1
 FAM13A antisense RNA 1
 16579
 0.18
chr1_12187961_12188288 0.32 TNFRSF8
 tumor necrosis factor receptor superfamily, member 8
 2168
 0.27
chr12_132670911_132671119 0.32 GALNT9
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
 19322
 0.17
chr1_111753742_111753893 0.32 DENND2D
 DENN/MADD domain containing 2D
 6786
 0.13
chr1_221331366_221331595 0.32 HLX
 H2.0-like homeobox
 276896
 0.01
chr10_134149618_134149848 0.32 LRRC27
 leucine rich repeat containing 27
 535
 0.78
chr7_37433310_37433642 0.31 ENSG00000200113
 .
 25755
 0.17
chr4_90992615_90992766 0.31 CCSER1
 coiled-coil serine-rich protein 1
 56046
 0.17
chr8_125025652_125025803 0.31 RP11-959I15.4
26982
 0.16
chr5_67337750_67337901 0.31 ENSG00000223149
 .
 74552
 0.12
chr6_139866152_139866378 0.31 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 170508
 0.04
chr16_3123541_3123818 0.31 ENSG00000252561
 .
 4155
 0.07
chr5_111189844_111190137 0.31 NREP-AS1
 NREP antisense RNA 1
 58215
 0.14
chr15_26038374_26038525 0.31 ENSG00000199214
 .
 24681
 0.17
chr16_29753056_29753330 0.31 AC009133.17
3375
 0.12
chr18_74766337_74766717 0.31 MBP
 myelin basic protein
 36793
 0.2
chr12_65060389_65060574 0.31 RP11-338E21.3
11682
 0.14
chr1_150134243_150134472 0.31 PLEKHO1
 pleckstrin homology domain containing, family O member 1
 5234
 0.16
chr4_4945545_4945811 0.31 ENSG00000200761
 .
 22887
 0.22
chr9_71354597_71354803 0.31 PIP5K1B
 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
 50
 0.98
chr1_110428379_110428629 0.31 RP11-195M16.1
382
 0.85
chr2_99350910_99351516 0.31 MGAT4A
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
 3624
 0.28
chr3_63920805_63920980 0.31 ATXN7
 ataxin 7
 22617
 0.15
chr4_8729255_8729406 0.31 CPZ
 carboxypeptidase Z
 125633
 0.05
chr9_126440524_126440675 0.31 DENND1A
 DENN/MADD domain containing 1A
 26269
 0.21
chr9_86184374_86184547 0.31 ENSG00000199483
 .
 27039
 0.16
chr10_98432809_98433283 0.31 PIK3AP1
 phosphoinositide-3-kinase adaptor protein 1
 3678
 0.27
chr2_192539739_192540059 0.31 NABP1
 nucleic acid binding protein 1
 2963
 0.38
chr4_55574901_55575221 0.31 KIT
 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
 50976
 0.18
chr17_76410308_76410576 0.31 PGS1
 phosphatidylglycerophosphate synthase 1
 10397
 0.13
chr13_114817282_114817433 0.30 RASA3
 RAS p21 protein activator 3
 26081
 0.22
chr7_50325429_50325697 0.30 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 18761
 0.26

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF691

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 0.2 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.3 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.1 0.2 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1 0.4 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0043299 natural killer cell activation involved in immune response(GO:0002323) leukocyte degranulation(GO:0043299) natural killer cell degranulation(GO:0043320)
0.0 0.1 GO:0045341 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.3 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.1 GO:0022009 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0035930 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.2 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0048143 astrocyte activation(GO:0048143)
0.0 0.1 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.2 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.2 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.1 GO:0010613 positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.0 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.0 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.0 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0045217 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.0 GO:0051873 disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0010887 negative regulation of cholesterol storage(GO:0010887)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.0 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.3 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0046666 retinal cell programmed cell death(GO:0046666) regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.0 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.1 GO:0033151 V(D)J recombination(GO:0033151)
0.0 0.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.0 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0002604 dendritic cell antigen processing and presentation(GO:0002468) regulation of antigen processing and presentation(GO:0002577) positive regulation of antigen processing and presentation(GO:0002579) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.0 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0021780 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.3 GO:0032613 interleukin-10 production(GO:0032613)
0.0 0.2 GO:0042119 granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.0 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.1 GO:0009215 purine deoxyribonucleotide metabolic process(GO:0009151) purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0006911 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.2 GO:0090181 regulation of cholesterol metabolic process(GO:0090181)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.0 GO:0002448 mast cell mediated immunity(GO:0002448)
0.0 0.1 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.3 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:0051569 regulation of histone H3-K4 methylation(GO:0051569)
0.0 0.1 GO:0045176 apical protein localization(GO:0045176)
0.0 0.0 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.0 GO:0010535 regulation of activation of Janus kinase activity(GO:0010533) regulation of activation of JAK2 kinase activity(GO:0010534) positive regulation of activation of JAK2 kinase activity(GO:0010535) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0010165 response to X-ray(GO:0010165)
0.0 0.0 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.0 GO:2000757 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.0 GO:0045978 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.0 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:1903299 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.0 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.0 GO:0046877 regulation of saliva secretion(GO:0046877)
0.0 0.0 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0060192 negative regulation of lipase activity(GO:0060192)
0.0 0.0 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.2 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0060334 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.0 0.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:1901374 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.1 GO:0016556 mRNA modification(GO:0016556)
0.0 0.0 GO:0090177 establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0 0.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0009264 deoxyribonucleotide catabolic process(GO:0009264)
0.0 0.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0002092 positive regulation of receptor internalization(GO:0002092)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.0 GO:0006837 serotonin transport(GO:0006837)
0.0 0.0 GO:0042663 endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.2 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.0 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.7 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.0 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.2 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.2 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.4 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.5 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.2 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.1 0.2 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.5 GO:0019864 IgG binding(GO:0019864)
0.1 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.2 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0034594 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.4 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.2 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.4 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.0 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.0 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.3 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.0 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.0 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.0 GO:0005131 growth hormone receptor binding(GO:0005131)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 0.2 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.0 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.1 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.0 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.0 REACTOME G1 S TRANSITION Genes involved in G1/S Transition
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1