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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ZNF740_ZNF219

Z-value: 0.97

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Transcription factors associated with ZNF740_ZNF219

Gene Symbol Gene ID Gene Info
ZNF740
ENSG00000139651.9 ZNF740
ZNF219
ENSG00000165804.11 ZNF219

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
ZNF219chr14_21567463_215677994580.454825-0.713.1e-02Click!
ZNF219chr14_21560976_215611439280.3714170.684.3e-02Click!
ZNF219chr14_21557704_2155785542080.1069340.665.4e-02Click!
ZNF219chr14_21556036_2155654456970.0969190.521.5e-01Click!
ZNF219chr14_21552997_2155314889150.0876300.432.4e-01Click!

Activity of the ZNF740_ZNF219 motif across conditions

Conditions sorted by the z-value of the ZNF740_ZNF219 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_11203608_11204588 0.46 CELF2
 CUGBP, Elav-like family member 2
 2895
 0.29
chr5_175916247_175916556 0.36 ENSG00000221373
 .
 37638
 0.09
chr5_75680037_75680677 0.36 IQGAP2
 IQ motif containing GTPase activating protein 2
 18717
 0.25
chr15_31657045_31657355 0.35 KLF13
 Kruppel-like factor 13
 1157
 0.65
chrX_102940963_102941114 0.34 MORF4L2
 mortality factor 4 like 2
 111
 0.93
chr1_27929391_27929542 0.33 AHDC1
 AT hook, DNA binding motif, containing 1
 636
 0.66
chr10_126849591_126849742 0.33 CTBP2
 C-terminal binding protein 2
 36
 0.99
chr2_134884979_134885130 0.32 ENSG00000263813
 .
 358
 0.9
chr17_76122728_76122959 0.31 TMC6
 transmembrane channel-like 6
 258
 0.86
chr11_66046306_66046457 0.31 CNIH2
 cornichon family AMPA receptor auxiliary protein 2
 711
 0.33
chr2_99377617_99378126 0.30 ENSG00000201070
 .
 21002
 0.19
chr18_22931267_22931732 0.30 ZNF521
 zinc finger protein 521
 80
 0.98
chr2_106459235_106459386 0.29 NCK2
 NCK adaptor protein 2
 8894
 0.24
chr15_77305575_77305811 0.28 PSTPIP1
 proline-serine-threonine phosphatase interacting protein 1
 2459
 0.29
chr11_68295708_68295914 0.27 PPP6R3
 protein phosphatase 6, regulatory subunit 3
 7068
 0.19
chr18_77280687_77280838 0.27 AC018445.1
 Uncharacterized protein
 4705
 0.31
chr21_44204010_44204161 0.26 AP001627.1
42217
 0.15
chr3_13026960_13027112 0.26 IQSEC1
 IQ motif and Sec7 domain 1
 1500
 0.52
chr8_144717528_144717700 0.25 ZNF623
 zinc finger protein 623
 569
 0.48
chr10_14641210_14641531 0.25 FAM107B
 family with sequence similarity 107, member B
 5018
 0.26
chr2_136885184_136885335 0.25 CXCR4
 chemokine (C-X-C motif) receptor 4
 9524
 0.29
chr3_178787798_178787973 0.24 ZMAT3
 zinc finger, matrin-type 3
 1469
 0.45
chr17_72743484_72743750 0.24 ENSG00000264624
 .
 1135
 0.23
chr3_17774733_17775005 0.24 TBC1D5
 TBC1 domain family, member 5
 7530
 0.31
chr7_19155701_19156072 0.24 TWIST1
 twist family bHLH transcription factor 1
 1409
 0.34
chr14_99730566_99730874 0.24 AL109767.1
1435
 0.45
chr19_13025260_13025411 0.24 SYCE2
 synaptonemal complex central element protein 2
 4755
 0.07
chr12_72055858_72056376 0.24 THAP2
 THAP domain containing, apoptosis associated protein 2
 672
 0.58
chr2_113402705_113402940 0.23 SLC20A1
 solute carrier family 20 (phosphate transporter), member 1
 612
 0.75
chr18_77282001_77282189 0.23 AC018445.1
 Uncharacterized protein
 6038
 0.3
chr9_92092219_92092635 0.23 SEMA4D
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
 2378
 0.35
chr1_156629969_156630120 0.22 RP11-284F21.7
1172
 0.28
chr19_2303224_2303375 0.22 LINGO3
 leucine rich repeat and Ig domain containing 3
 4857
 0.1
chr9_97022637_97022801 0.22 ZNF169
 zinc finger protein 169
 1109
 0.46
chr8_27198953_27199192 0.22 PTK2B
 protein tyrosine kinase 2 beta
 14732
 0.2
chr18_77280955_77281122 0.22 AC018445.1
 Uncharacterized protein
 4981
 0.31
chr1_79111221_79111724 0.22 IFI44
 interferon-induced protein 44
 4044
 0.25
chr1_154985178_154985329 0.21 ZBTB7B
 zinc finger and BTB domain containing 7B
 1671
 0.16
chr13_31313160_31313326 0.21 ALOX5AP
 arachidonate 5-lipoxygenase-activating protein
 3598
 0.34
chr1_167415328_167415582 0.21 RP11-104L21.2
12443
 0.21
chr16_50700983_50701245 0.21 RP11-401P9.5
992
 0.45
chr16_81815354_81815505 0.21 PLCG2
 phospholipase C, gamma 2 (phosphatidylinositol-specific)
 2566
 0.4
chr1_154465561_154465817 0.21 SHE
 Src homology 2 domain containing E
 4047
 0.14
chr10_61659889_61660066 0.21 CCDC6
 coiled-coil domain containing 6
 6437
 0.28
chr2_8444024_8444411 0.21 AC011747.7
371679
 0.01
chr19_33769711_33769869 0.21 CTD-2540B15.11
21050
 0.11
chr1_84326924_84327075 0.21 ENSG00000223231
 .
 67439
 0.13
chr14_21082227_21082378 0.20 RNASE11
 ribonuclease, RNase A family, 11 (non-active)
 4259
 0.13
chr3_52930379_52930530 0.20 TMEM110-MUSTN1
 TMEM110-MUSTN1 readthrough
 1124
 0.33
chr22_19752877_19753143 0.20 TBX1
 T-box 1
 8784
 0.18
chr5_137429102_137429305 0.20 WNT8A
 wingless-type MMTV integration site family, member 8A
 9429
 0.11
chr7_77564423_77564574 0.20 ENSG00000222432
 .
 39301
 0.17
chr4_146542708_146542859 0.20 MMAA
 methylmalonic aciduria (cobalamin deficiency) cblA type
 3368
 0.26
chr1_200987046_200987749 0.20 KIF21B
 kinesin family member 21B
 5139
 0.21
chr10_131769782_131769953 0.20 EBF3
 early B-cell factor 3
 7762
 0.31
chr17_29820821_29821086 0.20 RAB11FIP4
 RAB11 family interacting protein 4 (class II)
 5827
 0.15
chr22_36801197_36801348 0.20 MYH9
 myosin, heavy chain 9, non-muscle
 17209
 0.15
chr19_7744064_7744215 0.20 CTD-3214H19.16
752
 0.37
chr2_109241859_109242070 0.20 LIMS1
 LIM and senescent cell antigen-like domains 1
 4242
 0.27
chr4_78722788_78722939 0.20 CNOT6L
 CCR4-NOT transcription complex, subunit 6-like
 17354
 0.25
chr9_96229432_96229584 0.20 FAM120AOS
 family with sequence similarity 120A opposite strand
 13634
 0.14
chr10_14919889_14920040 0.20 SUV39H2
 suppressor of variegation 3-9 homolog 2 (Drosophila)
 883
 0.58
chr9_102855874_102856025 0.19 ERP44
 endoplasmic reticulum protein 44
 5373
 0.2
chr9_126030120_126030336 0.19 STRBP
 spermatid perinuclear RNA binding protein
 615
 0.81
chr1_151802545_151802942 0.19 RORC
 RAR-related orphan receptor C
 1483
 0.2
chr22_20784316_20784467 0.19 SCARF2
 scavenger receptor class F, member 2
 7721
 0.11
chr3_191047673_191047824 0.19 UTS2B
 urotensin 2B
 514
 0.64
chrX_100664537_100664740 0.19 HNRNPH2
 heterogeneous nuclear ribonucleoprotein H2 (H')
 1355
 0.25
chr17_74269143_74269364 0.19 QRICH2
 glutamine rich 2
 7185
 0.13
chrX_44768647_44768798 0.19 ENSG00000252113
 .
 23971
 0.2
chr10_8094760_8094911 0.19 GATA3
 GATA binding protein 3
 1821
 0.52
chr1_234349337_234349623 0.19 SLC35F3
 solute carrier family 35, member F3
 537
 0.68
chr9_139482691_139482911 0.19 ENSG00000252440
 .
 14166
 0.1
chr8_27181557_27182090 0.19 PTK2B
 protein tyrosine kinase 2 beta
 1039
 0.56
chr1_155036684_155036860 0.19 EFNA4
 ephrin-A4
 535
 0.37
chr22_30582834_30583084 0.19 RP3-438O4.4
20139
 0.13
chrX_128908006_128908241 0.19 SASH3
 SAM and SH3 domain containing 3
 5837
 0.21
chr14_91859539_91859984 0.18 CCDC88C
 coiled-coil domain containing 88C
 23929
 0.2
chr17_7789286_7789521 0.18 LSMD1
 LSM domain containing 1
 876
 0.33
chr8_38324368_38324696 0.18 FGFR1
 fibroblast growth factor receptor 1
 319
 0.88
chr11_2326434_2326626 0.18 TSPAN32
 tetraspanin 32
 2432
 0.18
chr14_91873415_91873761 0.18 CCDC88C
 coiled-coil domain containing 88C
 10102
 0.24
chr2_27615435_27615612 0.18 ZNF513
 zinc finger protein 513
 11866
 0.08
chr17_79420586_79420890 0.18 ENSG00000266189
 .
 2524
 0.16
chr17_29819355_29819635 0.18 RAB11FIP4
 RAB11 family interacting protein 4 (class II)
 4369
 0.16
chr1_167408168_167408319 0.18 RP11-104L21.2
19655
 0.19
chr8_128746908_128747308 0.17 MYC
 v-myc avian myelocytomatosis viral oncogene homolog
 572
 0.84
chr12_133055280_133055431 0.17 MUC8
 mucin 8
 4629
 0.23
chr6_90868295_90868522 0.17 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 138053
 0.04
chr11_64012927_64013269 0.17 PPP1R14B
 protein phosphatase 1, regulatory (inhibitor) subunit 14B
 190
 0.61
chr2_145275512_145275663 0.17 ZEB2-AS1
 ZEB2 antisense RNA 1
 77
 0.56
chr14_100525569_100526087 0.17 EVL
 Enah/Vasp-like
 5787
 0.17
chr1_26612161_26612476 0.17 SH3BGRL3
 SH3 domain binding glutamic acid-rich protein like 3
 5705
 0.12
chr17_66251665_66252057 0.17 ARSG
 arylsulfatase G
 3462
 0.19
chr15_78330161_78330463 0.17 ENSG00000221476
 .
 561
 0.69
chr17_66203318_66203469 0.17 AMZ2
 archaelysin family metallopeptidase 2
 40322
 0.12
chr17_39941615_39941766 0.17 JUP
 junction plakoglobin
 283
 0.83
chr1_198490580_198490731 0.17 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
 19149
 0.27
chr7_2739159_2739434 0.16 AMZ1
 archaelysin family metallopeptidase 1
 11460
 0.21
chr8_22299308_22299495 0.16 PPP3CC
 protein phosphatase 3, catalytic subunit, gamma isozyme
 523
 0.74
chr15_69075380_69075658 0.16 ENSG00000265195
 .
 18745
 0.22
chr14_64966305_64966456 0.16 ZBTB1
 zinc finger and BTB domain containing 1
 4063
 0.14
chr16_49892506_49892687 0.16 ZNF423
 zinc finger protein 423
 766
 0.73
chr22_36557619_36557770 0.16 APOL3
 apolipoprotein L, 3
 717
 0.72
chr4_154417485_154417761 0.16 KIAA0922
 KIAA0922
 30122
 0.21
chr7_949490_949865 0.16 ADAP1
 ArfGAP with dual PH domains 1
 4963
 0.16
chr19_16475924_16476075 0.16 EPS15L1
 epidermal growth factor receptor pathway substrate 15-like 1
 3235
 0.2
chr11_128600956_128601302 0.16 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
 33556
 0.15
chr3_183980771_183980922 0.16 CAMK2N2
 calcium/calmodulin-dependent protein kinase II inhibitor 2
 1595
 0.22
chr6_17601986_17602159 0.16 FAM8A1
 family with sequence similarity 8, member A1
 1486
 0.44
chr1_243622637_243622945 0.16 RP11-269F20.1
86043
 0.09
chr3_71287500_71287651 0.16 FOXP1
 forkhead box P1
 6741
 0.29
chr1_902652_902803 0.15 PLEKHN1
 pleckstrin homology domain containing, family N member 1
 845
 0.39
chr18_57025739_57025916 0.15 LMAN1
 lectin, mannose-binding, 1
 1367
 0.48
chr17_15495904_15496128 0.15 CDRT1
 CMT1A duplicated region transcript 1
 706
 0.58
chr13_99993452_99993845 0.15 ENSG00000207719
 .
 14737
 0.19
chr5_176514554_176514864 0.15 FGFR4
 fibroblast growth factor receptor 4
 289
 0.9
chr5_170815911_170816235 0.15 NPM1
 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
 1188
 0.38
chr17_39930444_39930595 0.15 JUP
 junction plakoglobin
 1998
 0.19
chr7_3152682_3152883 0.15 AC091801.1
 LOC392621; Uncharacterized protein
 45106
 0.16
chr5_159932695_159932967 0.15 ENSG00000253522
 .
 20472
 0.17
chr11_68530734_68530885 0.15 MTL5
 metallothionein-like 5, testis-specific (tesmin)
 11777
 0.2
chr17_79005380_79005531 0.15 BAIAP2
 BAI1-associated protein 2
 3495
 0.16
chr16_30935176_30935327 0.15 FBXL19
 F-box and leucine-rich repeat protein 19
 167
 0.8
chr14_65878762_65878997 0.15 FUT8
 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
 225
 0.95
chr19_45738680_45738986 0.15 EXOC3L2
 exocyst complex component 3-like 2
 1364
 0.32
chr22_39487886_39488384 0.15 RP4-742C19.12
544
 0.68
chr2_227663405_227663664 0.15 IRS1
 insulin receptor substrate 1
 941
 0.59
chr1_109816776_109816927 0.15 PSRC1
 proline/serine-rich coiled-coil 1
 7450
 0.15
chr3_46244229_46244380 0.15 CCR1
 chemokine (C-C motif) receptor 1
 5583
 0.25
chr13_41139475_41139713 0.15 AL133318.1
 Uncharacterized protein
 28271
 0.22
chr5_133437895_133438046 0.15 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 12432
 0.22
chr3_38039585_38039999 0.15 VILL
 villin-like
 4148
 0.16
chr1_33282419_33282585 0.15 S100PBP
 S100P binding protein
 134
 0.93
chr17_40937018_40937222 0.14 WNK4
 WNK lysine deficient protein kinase 4
 4424
 0.09
chr5_180338131_180338282 0.14 ENSG00000222852
 .
 1368
 0.33
chr19_1609011_1609503 0.14 UQCR11
 ubiquinol-cytochrome c reductase, complex III subunit XI
 3777
 0.11
chr17_55681912_55682272 0.14 RP11-118E18.4
3681
 0.24
chr17_44229938_44230089 0.14 KANSL1
 KAT8 regulatory NSL complex subunit 1
 19530
 0.15
chr16_81554932_81555083 0.14 CMIP
 c-Maf inducing protein
 26053
 0.24
chr3_139107166_139107509 0.14 ENSG00000252245
 .
 218
 0.84
chr2_239323617_239323768 0.14 ENSG00000202099
 .
 2409
 0.26
chr18_13612636_13612881 0.14 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
 140
 0.93
chrX_30589733_30589884 0.14 CXorf21
 chromosome X open reading frame 21
 6153
 0.27
chr17_79318286_79318703 0.14 TMEM105
 transmembrane protein 105
 14020
 0.13
chr16_53421654_53421805 0.14 RP11-44F14.1
14734
 0.16
chr11_119545202_119545353 0.14 ENSG00000199217
 .
 18256
 0.18
chr1_205243235_205243736 0.14 TMCC2
 transmembrane and coiled-coil domain family 2
 18156
 0.15
chr2_64835263_64835414 0.14 ENSG00000252414
 .
 29312
 0.17
chrX_78337599_78337998 0.14 GPR174
 G protein-coupled receptor 174
 88671
 0.1
chr8_11313733_11313920 0.14 FAM167A
 family with sequence similarity 167, member A
 10450
 0.15
chr14_99950613_99950764 0.14 CCNK
 cyclin K
 2926
 0.2
chr1_23856240_23856391 0.14 E2F2
 E2F transcription factor 2
 1397
 0.41
chr10_21805327_21805676 0.14 SKIDA1
 SKI/DACH domain containing 1
 1347
 0.33
chr19_17637669_17637829 0.14 FAM129C
 family with sequence similarity 129, member C
 298
 0.81
chr20_61558751_61558930 0.14 DIDO1
 death inducer-obliterator 1
 985
 0.48
chr2_85166364_85166744 0.14 KCMF1
 potassium channel modulatory factor 1
 31662
 0.15
chrX_30848915_30849066 0.14 TAB3-AS1
 TAB3 antisense RNA 1
 3750
 0.23
chr1_10753317_10753525 0.14 CASZ1
 castor zinc finger 1
 48288
 0.13
chr16_28156476_28156809 0.14 XPO6
 exportin 6
 24580
 0.16
chr10_102982257_102982408 0.14 LBX1-AS1
 LBX1 antisense RNA 1 (head to head)
 7019
 0.15
chr14_93798178_93798526 0.14 BTBD7
 BTB (POZ) domain containing 7
 340
 0.8
chr14_24046924_24047247 0.14 JPH4
 junctophilin 4
 909
 0.42
chr1_247693623_247693886 0.14 OR2C3
 olfactory receptor, family 2, subfamily C, member 3
 3387
 0.15
chr1_236051628_236051779 0.14 LYST
 lysosomal trafficking regulator
 4831
 0.19
chr2_95719306_95719457 0.13 AC103563.9
460
 0.79
chr15_79383402_79383553 0.13 RASGRF1
 Ras protein-specific guanine nucleotide-releasing factor 1
 362
 0.89
chrX_48648064_48648437 0.13 GATA1
 GATA binding protein 1 (globin transcription factor 1)
 3269
 0.13
chr6_36169985_36170141 0.13 BRPF3
 bromodomain and PHD finger containing, 3
 1989
 0.28
chr9_129326429_129326580 0.13 ENSG00000221173
 .
 12405
 0.18
chr7_151215555_151215799 0.13 RHEB
 Ras homolog enriched in brain
 522
 0.78
chr5_180632651_180632802 0.13 CTC-338M12.1
394
 0.43
chr19_54378263_54378435 0.13 AC008440.5
954
 0.29
chr2_242802197_242802348 0.13 PDCD1
 programmed cell death 1
 1212
 0.32
chr3_114865147_114865298 0.13 ZBTB20
 zinc finger and BTB domain containing 20
 896
 0.76
chr9_95857394_95857545 0.13 RP11-274J16.5
342
 0.77
chr5_176924121_176924335 0.13 PDLIM7
 PDZ and LIM domain 7 (enigma)
 334
 0.76
chr17_79140382_79140553 0.13 AATK
 apoptosis-associated tyrosine kinase
 650
 0.45
chr1_24645534_24645796 0.13 GRHL3
 grainyhead-like 3 (Drosophila)
 147
 0.95
chr12_6714982_6715407 0.13 CHD4
 chromodomain helicase DNA binding protein 4
 652
 0.48
chr3_55521660_55522023 0.13 WNT5A-AS1
 WNT5A antisense RNA 1
 114
 0.87
chr9_126108320_126108471 0.13 CRB2
 crumbs homolog 2 (Drosophila)
 10054
 0.24
chr11_30346022_30346188 0.13 ARL14EP
 ADP-ribosylation factor-like 14 effector protein
 1507
 0.54
chr22_30683089_30683240 0.13 GATSL3
 GATS protein-like 3
 2432
 0.15
chr9_33817398_33817619 0.13 UBE2R2
 ubiquitin-conjugating enzyme E2R 2
 57
 0.94
chrX_39920814_39920965 0.13 BCOR
 BCL6 corepressor
 1301
 0.62
chr19_40973350_40973501 0.13 SPTBN4
 spectrin, beta, non-erythrocytic 4
 299
 0.81
chr5_55982532_55982749 0.13 AC022431.2
 Homo sapiens uncharacterized LOC101928448 (LOC101928448), mRNA.
 80581
 0.09
chr4_2965787_2965938 0.13 GRK4
 G protein-coupled receptor kinase 4
 274
 0.77
chr2_143871194_143871345 0.13 ARHGAP15
 Rho GTPase activating protein 15
 15614
 0.25
chr2_96811667_96811891 0.13 DUSP2
 dual specificity phosphatase 2
 600
 0.68
chr8_81070516_81070667 0.13 TPD52
 tumor protein D52
 12844
 0.2
chr12_124762466_124762617 0.13 FAM101A
 family with sequence similarity 101, member A
 11169
 0.25
chr1_26697390_26697759 0.13 ZNF683
 zinc finger protein 683
 333
 0.82
chr4_8231324_8231505 0.13 SH3TC1
 SH3 domain and tetratricopeptide repeats 1
 11157
 0.22
chr2_172105282_172105509 0.13 TLK1
 tousled-like kinase 1
 17571
 0.25
chr20_50016749_50017039 0.13 ENSG00000263645
 .
 23036
 0.23
chr1_77748623_77748894 0.13 AK5
 adenylate kinase 5
 6
 0.98
chr10_134266352_134266533 0.13 C10orf91
 chromosome 10 open reading frame 91
 7749
 0.19
chr18_43761205_43761356 0.13 C18orf25
 chromosome 18 open reading frame 25
 7280
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ZNF740_ZNF219

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.2 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.1 0.2 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.1 0.2 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.3 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.3 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.0 0.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.0 GO:0072160 nephron tubule epithelial cell differentiation(GO:0072160) regulation of nephron tubule epithelial cell differentiation(GO:0072182) regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.1 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.0 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537)
0.0 0.1 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.0 GO:0072217 negative regulation of metanephros development(GO:0072217)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.1 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.0 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:0060992 response to fungicide(GO:0060992)
0.0 0.0 GO:2000351 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:1903313 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.0 GO:0002885 positive regulation of hypersensitivity(GO:0002885)
0.0 0.1 GO:0051798 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.0 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.0 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:1901534 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.0 GO:0043173 nucleotide salvage(GO:0043173)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.0 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.0 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.0 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.0 GO:0003179 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.0 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.0 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.0 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.0 GO:0071071 regulation of phosphatidylinositol biosynthetic process(GO:0010511) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.0 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.0 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0032462 regulation of protein homooligomerization(GO:0032462)
0.0 0.0 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.0 GO:0072189 ureter development(GO:0072189) kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.0 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0030260 entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.0 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0042756 drinking behavior(GO:0042756)
0.0 0.0 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.0 GO:0051096 positive regulation of helicase activity(GO:0051096)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0043209 myelin sheath(GO:0043209)
0.0 0.0 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.0 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.0 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0034739 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.0 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.0 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.0 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors