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ENCODE: H3K4me1 ChIP-Seq of primary human cells
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Results for ZSCAN4

Z-value: 2.20

Motif logo

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Transcription factors associated with ZSCAN4

Gene Symbol Gene ID Gene Info
ZSCAN4
ENSG00000180532.6 zinc finger and SCAN domain containing 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr19_58175635_58175905ZSCAN445330.104192-0.655.9e-02Click!
chr19_58162753_58162904ZSCAN4174750.081752-0.472.0e-01Click!
chr19_58175990_58176430ZSCAN440930.107979-0.176.7e-01Click!

Activity of the ZSCAN4 motif across conditions

Conditions sorted by the z-value of the ZSCAN4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_10529958_10530965 1.59 CDC37
 cell division cycle 37
 336
 0.7
chr16_88338584_88338864 1.54 ZNF469
 zinc finger protein 469
 155155
 0.03
chr3_196043643_196044552 1.45 TCTEX1D2
 Tctex1 domain containing 2
 1062
 0.29
chr19_33764735_33765354 1.08 CTD-2540B15.11
25796
 0.11
chr5_139049687_139050600 1.00 CXXC5
 CXXC finger protein 5
 4878
 0.24
chr10_77229212_77229699 0.97 RP11-399K21.10
38109
 0.16
chr12_57542255_57543089 0.95 RP11-545N8.3
1270
 0.29
chr17_79392708_79392859 0.94 RP11-1055B8.7
 BAH and coiled-coil domain-containing protein 1
 12613
 0.1
chr5_111077374_111077744 0.94 STARD4-AS1
 STARD4 antisense RNA 1
 11473
 0.19
chr3_185536101_185536453 0.93 IGF2BP2
 insulin-like growth factor 2 mRNA binding protein 2
 2572
 0.33
chr17_25886952_25887281 0.86 KSR1
 kinase suppressor of ras 1
 22831
 0.19
chr3_81789805_81790284 0.85 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 2736
 0.44
chr2_20290862_20291052 0.85 RP11-644K8.1
39062
 0.13
chr1_43672188_43672506 0.82 ENSG00000199240
 .
 10259
 0.15
chr11_46315072_46315223 0.82 CREB3L1
 cAMP responsive element binding protein 3-like 1
 1530
 0.37
chr3_100279906_100280202 0.81 GPR128
 G protein-coupled receptor 128
 48379
 0.14
chr4_41144342_41144612 0.81 ENSG00000207198
 .
 28518
 0.18
chr13_24230757_24231140 0.81 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 77429
 0.1
chr12_26150271_26150549 0.79 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
 2473
 0.34
chr7_101457741_101458764 0.79 CUX1
 cut-like homeobox 1
 707
 0.73
chr11_61772970_61773448 0.79 AP003733.1
 Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
 37756
 0.11
chr22_20776716_20777046 0.78 ENSG00000207343
 .
 5692
 0.12
chr15_31630334_31631466 0.78 KLF13
 Kruppel-like factor 13
 1236
 0.62
chr9_111149869_111150020 0.78 ENSG00000222512
 .
 28735
 0.26
chr11_79125207_79125358 0.77 ENSG00000266570
 .
 7988
 0.21
chr10_17028667_17028818 0.76 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 2548
 0.41
chr17_76312953_76313854 0.75 SOCS3
 suppressor of cytokine signaling 3
 42752
 0.1
chr21_44913772_44914270 0.74 SIK1
 salt-inducible kinase 1
 67013
 0.12
chr5_100760236_100760486 0.73 ENSG00000264318
 .
 157173
 0.04
chr1_85786366_85786652 0.73 ENSG00000264380
 .
 36216
 0.12
chr12_66273849_66274290 0.73 RP11-366L20.2
 Uncharacterized protein
 1289
 0.45
chr20_23128161_23128342 0.72 ENSG00000201527
 .
 13357
 0.21
chr17_41016311_41016609 0.72 AOC4P
 amine oxidase, copper containing 4, pseudogene
 2836
 0.12
chr3_177624604_177624755 0.72 ENSG00000199858
 .
 100888
 0.09
chrX_13269027_13269605 0.71 GS1-600G8.3
59455
 0.14
chr9_16986844_16987092 0.71 ENSG00000241152
 .
 66931
 0.13
chr18_51667381_51667645 0.71 ENSG00000221058
 .
 54487
 0.14
chr13_98742061_98742212 0.71 FARP1
 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
 52680
 0.14
chr8_67041458_67041609 0.70 TRIM55
 tripartite motif containing 55
 2255
 0.38
chr10_90317782_90317933 0.70 RNLS
 renalase, FAD-dependent amine oxidase
 25090
 0.16
chr1_29563306_29564087 0.70 PTPRU
 protein tyrosine phosphatase, receptor type, U
 545
 0.71
chr10_30092663_30093124 0.69 SVIL
 supervillin
 68160
 0.12
chr12_63186239_63186390 0.68 ENSG00000200296
 .
 58367
 0.13
chr16_21115040_21115521 0.68 CTC-508F8.1
16799
 0.18
chr15_64189215_64189478 0.67 ENSG00000199156
 .
 26128
 0.17
chr7_34088060_34088211 0.67 BMPER
 BMP binding endothelial regulator
 142990
 0.05
chr5_138474799_138474993 0.67 SIL1
 SIL1 nucleotide exchange factor
 7449
 0.22
chr12_96230513_96230749 0.67 RP11-536G4.2
21945
 0.13
chr6_82724453_82724882 0.67 ENSG00000223044
 .
 195490
 0.03
chr2_175461673_175462147 0.66 WIPF1
 WAS/WASL interacting protein family, member 1
 583
 0.74
chr2_161070939_161071127 0.66 ITGB6
 integrin, beta 6
 14218
 0.28
chr4_13921909_13922060 0.66 ENSG00000252092
 .
 261733
 0.02
chr6_34203766_34204339 0.66 HMGA1
 high mobility group AT-hook 1
 598
 0.76
chr11_122048490_122048641 0.66 ENSG00000207994
 .
 25549
 0.16
chr6_157470812_157471091 0.65 ARID1B
 AT rich interactive domain 1B (SWI1-like)
 906
 0.68
chr4_129491179_129491364 0.65 ENSG00000238802
 .
 185910
 0.03
chr11_132491663_132491814 0.65 ENSG00000252703
 .
 96035
 0.09
chr10_104576110_104576351 0.64 ENSG00000252994
 .
 12544
 0.12
chr2_36593988_36594139 0.64 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 10449
 0.3
chr9_91433481_91433632 0.64 ENSG00000265873
 .
 72736
 0.12
chr5_173009603_173009754 0.64 CTB-33O18.3
3026
 0.32
chr13_111162756_111163013 0.64 COL4A2-AS1
 COL4A2 antisense RNA 1
 2358
 0.32
chr2_8143997_8144330 0.63 ENSG00000221255
 .
 427191
 0.01
chr9_113564994_113565275 0.63 MUSK
 muscle, skeletal, receptor tyrosine kinase
 27507
 0.23
chr21_36800534_36801386 0.63 ENSG00000211590
 .
 292053
 0.01
chr6_90021967_90022444 0.63 GABRR2
 gamma-aminobutyric acid (GABA) A receptor, rho 2
 2762
 0.29
chr1_116610481_116610632 0.62 MAB21L3
 mab-21-like 3 (C. elegans)
 43820
 0.15
chr9_103192265_103192416 0.62 MSANTD3
 Myb/SANT-like DNA-binding domain containing 3
 2621
 0.24
chr5_55646128_55646279 0.62 ENSG00000210678
 .
 52687
 0.13
chr7_107580527_107580678 0.62 CTB-13F3.1
1959
 0.34
chr12_50581896_50582047 0.62 RP3-405J10.3
3175
 0.16
chr2_69361874_69362025 0.62 ENSG00000266649
 .
 31135
 0.15
chr15_50148578_50148980 0.61 ATP8B4
 ATPase, class I, type 8B, member 4
 20113
 0.21
chr2_121583155_121583306 0.61 GLI2
 GLI family zinc finger 2
 28309
 0.25
chr7_114583801_114583952 0.61 MDFIC
 MyoD family inhibitor domain containing
 9952
 0.32
chr17_76880562_76881090 0.61 TIMP2
 TIMP metallopeptidase inhibitor 2
 10594
 0.14
chr4_84540234_84540477 0.61 ENSG00000201633
 .
 17088
 0.25
chr6_116877582_116877733 0.60 FAM26D
 family with sequence similarity 26, member D
 2744
 0.19
chr10_60159885_60160036 0.60 TFAM
 transcription factor A, mitochondrial
 14596
 0.25
chr13_33685462_33685613 0.60 STARD13-IT1
 STARD13 intronic transcript 1 (non-protein coding)
 53009
 0.13
chr10_80732581_80733347 0.60 ZMIZ1-AS1
 ZMIZ1 antisense RNA 1
 10813
 0.3
chr14_52192816_52192967 0.60 ENSG00000207004
 .
 2070
 0.29
chr11_20052539_20052690 0.60 NAV2
 neuron navigator 2
 7978
 0.21
chr5_139058836_139059075 0.60 CXXC5
 CXXC finger protein 5
 313
 0.91
chrX_17518731_17518882 0.60 RP1-60N8.1
27752
 0.2
chr5_133842003_133842294 0.60 ENSG00000207222
 .
 6173
 0.17
chr3_150733701_150733898 0.60 CLRN1
 clarin 1
 43013
 0.13
chr20_49190043_49190194 0.60 RP4-530I15.9
4460
 0.15
chr2_223872304_223872455 0.60 KCNE4
 potassium voltage-gated channel, Isk-related family, member 4
 44153
 0.16
chr2_18481243_18481394 0.59 ENSG00000212455
 .
 259319
 0.02
chr5_111320399_111320550 0.59 NREP
 neuronal regeneration related protein
 7846
 0.24
chr3_11556641_11556792 0.59 VGLL4
 vestigial like 4 (Drosophila)
 53682
 0.15
chr12_2192011_2192162 0.59 CACNA1C
 calcium channel, voltage-dependent, L type, alpha 1C subunit
 29357
 0.15
chr1_12370157_12370308 0.59 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 33054
 0.18
chr3_100620980_100621131 0.59 ABI3BP
 ABI family, member 3 (NESH) binding protein
 12253
 0.26
chr10_120873283_120874145 0.58 FAM45A
 family with sequence similarity 45, member A
 10085
 0.14
chr6_11609999_11610289 0.58 TMEM170B
 transmembrane protein 170B
 71633
 0.11
chr8_25072026_25072201 0.58 DOCK5
 dedicator of cytokinesis 5
 29733
 0.2
chr16_73079012_73079217 0.58 ZFHX3
 zinc finger homeobox 3
 3160
 0.29
chr17_1902829_1903046 0.58 CTD-2545H1.2
4029
 0.12
chr9_116385560_116385711 0.58 RGS3
 regulator of G-protein signaling 3
 29869
 0.18
chr6_12491498_12491711 0.58 ENSG00000223321
 .
 84591
 0.11
chr14_100858592_100859044 0.58 WDR25
 WD repeat domain 25
 10481
 0.11
chr2_145765415_145765691 0.58 ENSG00000253036
 .
 327085
 0.01
chr2_33335733_33335884 0.58 LTBP1
 latent transforming growth factor beta binding protein 1
 23665
 0.25
chr14_23309465_23309695 0.58 MMP14
 matrix metallopeptidase 14 (membrane-inserted)
 3059
 0.11
chr5_72660072_72660394 0.57 FOXD1
 forkhead box D1
 84119
 0.08
chr4_38084488_38084755 0.57 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
 37129
 0.21
chr17_40070389_40070799 0.57 ACLY
 ATP citrate lyase
 4610
 0.14
chr6_157634572_157634748 0.57 ENSG00000252609
 .
 77771
 0.11
chr9_91566128_91566384 0.57 C9orf47
 chromosome 9 open reading frame 47
 39522
 0.17
chr19_13841374_13841557 0.57 CCDC130
 coiled-coil domain containing 130
 1109
 0.39
chr9_91770253_91770404 0.57 SHC3
 SHC (Src homology 2 domain containing) transforming protein 3
 23354
 0.21
chr10_16909413_16909564 0.57 RSU1
 Ras suppressor protein 1
 49961
 0.17
chr4_159835224_159835375 0.57 FNIP2
 folliculin interacting protein 2
 82067
 0.08
chr8_122653910_122654608 0.57 HAS2-AS1
 HAS2 antisense RNA 1
 583
 0.49
chr3_99795186_99795494 0.57 FILIP1L
 filamin A interacting protein 1-like
 38017
 0.15
chr2_204302778_204302929 0.56 ABI2
 abl-interactor 2
 47086
 0.15
chr9_131925764_131925959 0.56 RP11-247A12.8
12225
 0.11
chr10_127905326_127905477 0.56 ENSG00000222740
 .
 71250
 0.12
chr11_85885780_85885957 0.56 ENSG00000200877
 .
 21599
 0.2
chr8_57424165_57424316 0.56 RP11-17A4.2
22583
 0.24
chr12_127758735_127758886 0.56 ENSG00000253089
 .
 47090
 0.19
chr17_62051771_62052003 0.56 SCN4A
 sodium channel, voltage-gated, type IV, alpha subunit
 1609
 0.28
chr4_157415956_157416107 0.56 RP11-171N4.2
 Uncharacterized protein
 147428
 0.04
chr12_104400584_104400735 0.56 ENSG00000215976
 .
 21770
 0.12
chr4_3377977_3378128 0.56 RGS12
 regulator of G-protein signaling 12
 6446
 0.24
chr16_81659823_81659974 0.56 CMIP
 c-Maf inducing protein
 19065
 0.26
chr3_132262226_132262419 0.56 ACKR4
 atypical chemokine receptor 4
 53759
 0.14
chr3_42164747_42165041 0.56 TRAK1
 trafficking protein, kinesin binding 1
 25833
 0.22
chr15_48665560_48665810 0.56 DUT
 deoxyuridine triphosphatase
 41082
 0.14
chr13_38192314_38192465 0.56 POSTN
 periostin, osteoblast specific factor
 19408
 0.29
chr3_123475857_123476473 0.56 MYLK
 myosin light chain kinase
 36523
 0.15
chr1_230960513_230960664 0.55 ENSG00000202063
 .
 4592
 0.16
chr6_17417778_17417929 0.55 CAP2
 CAP, adenylate cyclase-associated protein, 2 (yeast)
 23910
 0.25
chr11_46302438_46302589 0.55 CREB3L1
 cAMP responsive element binding protein 3-like 1
 3285
 0.22
chr7_132075833_132075984 0.55 AC011625.1
38815
 0.21
chr3_98605745_98605896 0.55 DCBLD2
 discoidin, CUB and LCCL domain containing 2
 14195
 0.17
chrX_10724631_10724895 0.55 MID1
 midline 1 (Opitz/BBB syndrome)
 78984
 0.12
chr3_99296566_99296717 0.55 COL8A1
 collagen, type VIII, alpha 1
 60678
 0.15
chr3_52568281_52568866 0.55 NT5DC2
 5'-nucleotidase domain containing 2
 497
 0.65
chr1_178022073_178022224 0.55 RASAL2
 RAS protein activator like 2
 40716
 0.2
chr5_135329366_135329517 0.55 TGFBI
 transforming growth factor, beta-induced, 68kDa
 35143
 0.15
chr13_27557925_27558080 0.54 USP12-AS1
 USP12 antisense RNA 1
 178990
 0.03
chr1_110477243_110477394 0.54 CSF1
 colony stimulating factor 1 (macrophage)
 23710
 0.15
chr6_112651418_112651569 0.54 RFPL4B
 ret finger protein-like 4B
 17039
 0.19
chr10_127779169_127779320 0.54 ENSG00000222740
 .
 54907
 0.14
chr19_48167872_48168055 0.54 CTD-3001H11.1
38311
 0.1
chr7_101685192_101685568 0.54 CTA-357J21.1
9077
 0.25
chr6_80130765_80130973 0.54 LCA5
 Leber congenital amaurosis 5
 116256
 0.06
chr11_128635989_128636140 0.54 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
 1379
 0.49
chr7_94043117_94043268 0.54 COL1A2
 collagen, type I, alpha 2
 19319
 0.24
chr6_35185894_35186601 0.54 SCUBE3
 signal peptide, CUB domain, EGF-like 3
 4051
 0.24
chr10_99476322_99476473 0.54 MARVELD1
 MARVEL domain containing 1
 2916
 0.21
chr6_158463537_158463688 0.54 SYNJ2
 synaptojanin 2
 25115
 0.18
chr2_150598095_150598246 0.54 ENSG00000207270
 .
 130882
 0.05
chr1_183174832_183175122 0.53 LAMC2
 laminin, gamma 2
 19554
 0.22
chr7_11579949_11580217 0.53 AC004160.4
133501
 0.05
chr7_36343852_36344047 0.53 EEPD1
 endonuclease/exonuclease/phosphatase family domain containing 1
 7196
 0.18
chr10_15832078_15832229 0.53 FAM188A
 family with sequence similarity 188, member A
 27854
 0.22
chr1_234754493_234754778 0.53 IRF2BP2
 interferon regulatory factor 2 binding protein 2
 9364
 0.19
chr8_18710180_18710331 0.53 PSD3
 pleckstrin and Sec7 domain containing 3
 1629
 0.47
chr18_53664203_53664562 0.53 ENSG00000201816
 .
 82443
 0.11
chr1_64189357_64189508 0.53 ROR1
 receptor tyrosine kinase-like orphan receptor 1
 50261
 0.14
chr22_45846959_45847110 0.53 RP1-102D24.5
2410
 0.28
chr15_67797090_67797241 0.53 IQCH
 IQ motif containing H
 14812
 0.2
chr2_9404429_9404580 0.53 ASAP2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 57610
 0.15
chr17_40541111_40541280 0.53 STAT3
 signal transducer and activator of transcription 3 (acute-phase response factor)
 609
 0.62
chr3_34053419_34053570 0.53 PDCD6IP
 programmed cell death 6 interacting protein
 213379
 0.02
chr3_45969252_45969403 0.52 LZTFL1
 leucine zipper transcription factor-like 1
 11793
 0.14
chr6_44025617_44025876 0.52 RP5-1120P11.1
16643
 0.16
chr1_85164556_85164820 0.52 SSX2IP
 synovial sarcoma, X breakpoint 2 interacting protein
 8202
 0.24
chr8_12965677_12965828 0.52 DLC1
 deleted in liver cancer 1
 8001
 0.25
chr13_110979910_110980061 0.52 COL4A2
 collagen, type IV, alpha 2
 20371
 0.2
chr2_1740579_1740730 0.52 PXDN
 peroxidasin homolog (Drosophila)
 7560
 0.28
chr7_115910573_115910724 0.52 TES
 testis derived transcript (3 LIM domains)
 20159
 0.2
chr12_65700565_65700842 0.52 MSRB3
 methionine sulfoxide reductase B3
 19952
 0.21
chr1_154703230_154703438 0.52 ADAR
 adenosine deaminase, RNA-specific
 102860
 0.05
chr7_143716279_143716430 0.52 OR6B1
 olfactory receptor, family 6, subfamily B, member 1
 15332
 0.14
chr9_128507884_128508777 0.52 PBX3
 pre-B-cell leukemia homeobox 3
 1294
 0.56
chr12_65700883_65701407 0.52 MSRB3
 methionine sulfoxide reductase B3
 19510
 0.22
chr8_108512063_108512336 0.52 ANGPT1
 angiopoietin 1
 1916
 0.51
chr17_36620428_36620685 0.52 ARHGAP23
 Rho GTPase activating protein 23
 6912
 0.17
chr11_91712007_91712158 0.52 FAT3
 FAT atypical cadherin 3
 373180
 0.01
chr16_10652211_10652476 0.52 EMP2
 epithelial membrane protein 2
 668
 0.68
chr10_34816449_34816600 0.52 PARD3
 par-3 family cell polarity regulator
 100865
 0.08
chr16_10921575_10921749 0.52 TVP23A
 trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)
 9020
 0.18
chr1_201625847_201626084 0.51 NAV1
 neuron navigator 1
 8515
 0.15
chr11_19450352_19450503 0.51 ENSG00000200687
 .
 26899
 0.17
chr7_80413087_80413238 0.51 CD36
 CD36 molecule (thrombospondin receptor)
 110470
 0.07
chr3_134048924_134049075 0.51 AMOTL2
 angiomotin like 2
 41755
 0.16
chr5_72981992_72982143 0.51 ARHGEF28
 Rho guanine nucleotide exchange factor (GEF) 28
 1410
 0.51
chr11_1850163_1850314 0.51 SYT8
 synaptotagmin VIII
 465
 0.68
chr9_93889256_93889407 0.51 AUH
 AU RNA binding protein/enoyl-CoA hydratase
 234846
 0.02
chr1_114517819_114518204 0.51 OLFML3
 olfactomedin-like 3
 4052
 0.2
chr11_84610658_84610809 0.50 DLG2
 discs, large homolog 2 (Drosophila)
 23491
 0.23
chr9_135522417_135522761 0.50 DDX31
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
 16298
 0.19
chr12_88896800_88896951 0.50 ENSG00000199245
 .
 72656
 0.11
chrX_99903765_99903916 0.50 SRPX2
 sushi-repeat containing protein, X-linked 2
 4625
 0.2
chr8_99177472_99177908 0.50 ENSG00000252558
 .
 26851
 0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of ZSCAN4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.2 0.5 GO:0030091 protein repair(GO:0030091)
0.1 0.4 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.5 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.8 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.6 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.1 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.6 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.2 GO:1903301 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.1 0.5 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.3 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.4 GO:0016246 RNA interference(GO:0016246)
0.1 0.3 GO:0060992 response to fungicide(GO:0060992)
0.1 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.3 GO:0003179 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.1 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.2 GO:0032328 alanine transport(GO:0032328)
0.1 0.2 GO:0033023 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.2 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.2 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.3 GO:0002068 glandular epithelial cell development(GO:0002068)
0.1 0.1 GO:0072205 metanephric collecting duct development(GO:0072205)
0.1 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.1 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.1 0.2 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.2 GO:0090400 stress-induced premature senescence(GO:0090400)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.1 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.8 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.4 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0001553 luteinization(GO:0001553)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0014034 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.0 0.2 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.2 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.4 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.3 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0042663 endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.2 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0072177 nephric duct development(GO:0072176) mesonephric duct development(GO:0072177) nephric duct morphogenesis(GO:0072178) mesonephric duct morphogenesis(GO:0072180)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.3 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.0 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:1901978 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.4 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.0 GO:0014055 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:1901976 regulation of cell cycle checkpoint(GO:1901976)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.0 0.1 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.4 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.2 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0 0.1 GO:2000831 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0048143 astrocyte activation(GO:0048143)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.1 GO:0034445 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.2 GO:0034030 nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.0 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.0 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0061047 positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0014010 Schwann cell proliferation(GO:0014010)
0.0 0.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.1 GO:0016241 regulation of macroautophagy(GO:0016241)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.2 GO:0009219 pyrimidine deoxyribonucleotide metabolic process(GO:0009219)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.1 GO:0019511 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.4 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0060674 placenta blood vessel development(GO:0060674)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0050926 regulation of positive chemotaxis(GO:0050926)
0.0 0.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0045916 negative regulation of protein processing(GO:0010955) negative regulation of complement activation(GO:0045916) negative regulation of protein maturation(GO:1903318) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0001967 suckling behavior(GO:0001967)
0.0 0.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952) central nervous system neuron axonogenesis(GO:0021955)
0.0 0.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.0 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0090030 regulation of steroid hormone biosynthetic process(GO:0090030)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.0 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.1 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.1 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0071501 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.0 GO:0046083 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0071220 response to bacterial lipoprotein(GO:0032493) response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.0 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:1903428 positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.0 0.1 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
0.0 0.0 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.0 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0042819 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.0 GO:0018101 protein citrullination(GO:0018101)
0.0 0.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993)
0.0 0.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:2000379 positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.0 0.1 GO:0021772 olfactory bulb development(GO:0021772)
0.0 0.0 GO:0021554 optic nerve development(GO:0021554)
0.0 0.1 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.0 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.1 GO:0010092 specification of organ identity(GO:0010092)
0.0 0.0 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.0 GO:0060872 semicircular canal development(GO:0060872)
0.0 0.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.0 GO:0090037 regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0006837 serotonin transport(GO:0006837)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.3 GO:0016600 flotillin complex(GO:0016600)
0.1 0.4 GO:0031512 motile primary cilium(GO:0031512)
0.1 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.5 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0043205 fibril(GO:0043205)
0.0 0.2 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 1.1 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.7 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.0 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.0 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.0 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.0 GO:0001939 female pronucleus(GO:0001939)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.0 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.2 0.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.4 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.6 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.2 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.4 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0030332 cyclin binding(GO:0030332)
0.1 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0016595 glutamate binding(GO:0016595)
0.1 0.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0030553 cGMP binding(GO:0030553)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.3 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.3 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.0 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.1 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.0 GO:0070700 transmembrane receptor protein serine/threonine kinase binding(GO:0070696) BMP receptor binding(GO:0070700)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.0 PID MYC PATHWAY C-MYC pathway
0.0 2.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.0 PID IGF1 PATHWAY IGF1 pathway
0.0 0.0 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.1 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.6 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.0 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.0 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle