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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Alx4

Z-value: 3.70

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Transcription factors associated with Alx4

Gene Symbol	Gene ID	Gene Info
Alx4 Ensembl NCBI MGI UniProt	ENSMUSG00000040310.6	aristaless-like homeobox 4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_93642502_93642662	Alx4	194	0.959910	0.37	5.7e-03	Click!
chr2_93662426_93662770	Alx4	20210	0.205469	-0.36	7.1e-03	Click!
chr2_93642067_93642218	Alx4	242	0.946989	0.35	7.9e-03	Click!
chr2_93666598_93666749	Alx4	24285	0.192597	0.25	6.9e-02	Click!
chr2_93625118_93625505	Alx4	17073	0.230005	-0.16	2.5e-01	Click!

Activity of the Alx4 motif across conditions

Conditions sorted by the z-value of the Alx4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_11927079_11927230	29.32	Prkn	parkin RBR E3 ubiquitin protein ligase	81944	0.1
chr12_51002047_51002408	29.00	Gm40421	predicted gene, 40421	2646	0.28
chr13_99444397_99444879	28.16	Map1b	microtubule-associated protein 1B	171	0.95
chr2_106512677_106513062	27.92	Gm14015	predicted gene 14015	10234	0.26
chr11_112501711_112502406	26.67	BC006965	cDNA sequence BC006965	167340	0.04
chr12_4220043_4220458	26.36	Gm48210	predicted gene, 48210	1852	0.19
chr4_24429061_24429567	25.64	Gm27243	predicted gene 27243	1576	0.43
chr13_83750227_83750397	25.08	C130071C03Rik	RIKEN cDNA C130071C03 gene	11449	0.12
chrX_166344291_166344543	24.62	Gpm6b	glycoprotein m6b	275	0.93
chr6_54552680_54553127	24.15	Scrn1	secernin 1	1543	0.37
chr1_96346717_96347057	23.06	Gm37076	predicted gene, 37076	33645	0.18
chrX_169838405_169838582	22.73	Mid1	midline 1	10334	0.25
chr11_43270024_43270232	22.00	Gm12146	predicted gene 12146	10344	0.19
chr9_66933818_66934187	21.63	Rps27l	ribosomal protein S27-like	12084	0.15
chr2_56257440_56257969	21.58	Gm13518	predicted gene 13518	217851	0.02
chr16_52387159_52387325	21.36	Alcam	activated leukocyte cell adhesion molecule	65223	0.14
chr13_83739197_83739995	21.31	C130071C03Rik	RIKEN cDNA C130071C03 gene	733	0.33
chr8_26677560_26678005	21.13	Gm32098	predicted gene, 32098	9476	0.18
chr5_20056465_20056826	21.12	Gm23570	predicted gene, 23570	35970	0.2
chr13_83749857_83750036	20.98	C130071C03Rik	RIKEN cDNA C130071C03 gene	11083	0.12
chr1_20428787_20428938	20.96	Gm15795	predicted gene 15795	15948	0.17
chr16_63806441_63806811	20.87	Epha3	Eph receptor A3	56787	0.15
chr4_21095762_21096024	20.66	Gm11871	predicted gene 11871	84953	0.1
chr16_63747767_63748162	20.47	Gm22769	predicted gene, 22769	430	0.91
chr10_70484969_70485278	20.45	Gm29783	predicted gene, 29783	20125	0.19
chr3_66102086_66102567	20.03	Gm36973	predicted gene, 36973	2521	0.19
chr10_19318275_19318532	19.99	Gm33056	predicted gene, 33056	27414	0.17
chr15_18190039_18190239	19.67	Gm8318	predicted gene 8318	26258	0.22
chr12_29789878_29790063	19.65	Myt1l	myelin transcription factor 1-like	50240	0.17
chr3_78792451_78792970	19.62	Gm18952	predicted gene, 18952	34091	0.19
chr3_5326430_5327011	18.97	Zfhx4	zinc finger homeodomain 4	85048	0.09
chr1_67366568_67366878	18.92	Gm26342	predicted gene, 26342	109499	0.06
chr13_84783651_84783837	18.91	Gm26913	predicted gene, 26913	92803	0.09
chr2_132427639_132427949	18.84	4921508D12Rik	RIKEN cDNA 4921508D12 gene	3053	0.25
chr13_58964694_58965094	18.77	Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	93159	0.06
chr2_70127967_70128143	18.54	Myo3b	myosin IIIB	31757	0.19
chr6_55484275_55484600	18.52	Adcyap1r1	adenylate cyclase activating polypeptide 1 receptor 1	24201	0.19
chr13_84751597_84751791	18.46	Gm26913	predicted gene, 26913	60753	0.15
chr8_12126295_12126640	18.23	A230072I06Rik	RIKEN cDNA A230072I06 gene	152352	0.03
chr16_67610911_67611282	18.20	Cadm2	cell adhesion molecule 2	9397	0.25
chr7_74687903_74688273	18.18	Gm7726	predicted gene 7726	11768	0.26
chr8_31895464_31895660	18.17	Nrg1	neuregulin 1	8976	0.25
chr12_56458764_56459233	18.11	Sfta3-ps	surfactant associated 3, pseudogene	34326	0.12
chr11_47069891_47070050	17.98	Gm12175	predicted gene 12175	195557	0.03
chr13_52457883_52458068	17.96	Diras2	DIRAS family, GTP-binding RAS-like 2	73304	0.12
chr13_78324889_78325040	17.81	Gm3963	predicted gene 3963	37880	0.11
chr1_176099027_176099243	17.79	Gm38081	predicted gene, 38081	66412	0.1
chrX_61393166_61393371	17.73	Gm14665	predicted gene 14665	4241	0.3
chr2_41498351_41498548	17.66	Lrp1b	low density lipoprotein-related protein 1B	290629	0.01
chr5_107497898_107498054	17.62	Btbd8	BTB (POZ) domain containing 8	197	0.9
chr7_96865260_96865776	17.60	Gm25712	predicted gene, 25712	2139	0.28
chr1_81594178_81594459	17.50	Gm6198	predicted gene 6198	36835	0.2
chr17_56472537_56473329	17.37	Ptprs	protein tyrosine phosphatase, receptor type, S	1694	0.3
chr12_33225655_33225815	17.29	Atxn7l1os1	ataxin 7-like 1, opposite strand 1	3119	0.29
chr8_86961518_86961711	17.18	Gm24781	predicted gene, 24781	4005	0.19
chr8_47642536_47642697	17.17	Gm8623	predicted gene 8623	9852	0.12
chr2_50971381_50971555	17.16	Gm13498	predicted gene 13498	61784	0.14
chr19_30160000_30160313	16.97	Rpl31-ps20	ribosomal protein L31, pseudogene 20	464	0.82
chr9_61102454_61102622	16.96	4933433G08Rik	RIKEN cDNA 4933433G08 gene	2847	0.2
chr6_61066614_61066949	16.90	Gm43893	predicted gene, 43893	2474	0.28
chr3_40673604_40673797	16.88	Intu	inturned planar cell polarity protein	1079	0.49
chr17_66869624_66870037	16.85	Gm49940	predicted gene, 49940	7590	0.18
chr13_78580917_78581111	16.83	Gm48402	predicted gene, 48402	57003	0.14
chr12_50120116_50120285	16.81	Gm40418	predicted gene, 40418	109	0.98
chr3_18454033_18454237	16.75	Gm30667	predicted gene, 30667	7119	0.22
chr10_29143863_29144732	16.68	Gm9996	predicted gene 9996	103	0.69
chr12_90131976_90132183	16.67	Gm48700	predicted gene, 48700	63980	0.15
chr12_47163286_47163464	16.66	Gm36971	predicted gene, 36971	1667	0.48
chr10_70458638_70458831	16.58	Fam13c	family with sequence similarity 13, member C	17808	0.19
chr12_47164101_47164307	16.53	Gm36971	predicted gene, 36971	838	0.72
chr1_46829988_46830169	16.48	Slc39a10	solute carrier family 39 (zinc transporter), member 10	5821	0.22
chr8_90576969_90577137	16.47	Gm45639	predicted gene 45639	97905	0.07
chr11_28697993_28698421	16.45	2810471M01Rik	RIKEN cDNA 2810471M01 gene	16643	0.16
chr18_40059274_40059425	16.45	Gm50395	predicted gene, 50395	50384	0.16
chr16_91140532_91140860	16.25	Gm49612	predicted gene, 49612	5220	0.12
chr3_50014297_50014449	16.16	Gm37854	predicted gene, 37854	12401	0.22
chr13_71507941_71508418	16.13	1700112M02Rik	RIKEN cDNA 1700112M02 gene	20572	0.26
chr12_58670274_58670654	16.00	Gm18873	predicted gene, 18873	93442	0.08
chr16_43502947_43503194	15.91	Zbtb20	zinc finger and BTB domain containing 20	544	0.83
chr5_116895407_116895611	15.85	Gm43122	predicted gene 43122	64955	0.1
chr11_41532495_41533004	15.80	Hspd1-ps3	heat shock protein 1 (chaperonin), pseudogene 3	34012	0.2
chr5_84153090_84153587	15.77	Hmgn2-ps1	high mobility group nucleosomal binding domain 2, pseudogene 1	30025	0.25
chr1_168328003_168328211	15.74	Gm37524	predicted gene, 37524	9564	0.24
chr10_92097138_92097289	15.73	Rmst	rhabdomyosarcoma 2 associated transcript (non-coding RNA)	6576	0.22
chr19_59006658_59006882	15.70	Shtn1	shootin 1	31515	0.15
chr6_51767665_51767816	15.68	Gm38811	predicted gene, 38811	56659	0.13
chr18_27956389_27956743	15.60	Gm33674	predicted gene, 33674	146834	0.05
chr2_54265163_54265368	15.59	Gm14035	predicted gene 14035	18850	0.21
chrX_71700854_71701085	15.53	Gm14723	predicted gene 14723	26688	0.18
chr18_45014470_45014883	15.37	Gm31706	predicted gene, 31706	30186	0.16
chr8_87064278_87064454	15.30	Gm18602	predicted gene, 18602	12119	0.15
chr4_111004709_111005071	15.30	Agbl4	ATP/GTP binding protein-like 4	113951	0.07
chr1_159015364_159015547	15.28	Pappa2	pappalysin 2	34965	0.17
chr17_51536754_51537055	15.28	Gm31143	predicted gene, 31143	2046	0.39
chr10_46718838_46719012	15.26	Gm19994	predicted gene, 19994	48781	0.16
chr13_52562127_52562509	15.24	Syk	spleen tyrosine kinase	20855	0.22
chr4_71933713_71933873	15.21	Gm11234	predicted gene 11234	46684	0.17
chr2_63669900_63670081	15.17	Gm23503	predicted gene, 23503	237796	0.02
chr7_64884497_64884825	15.15	Nsmce3	NSE3 homolog, SMC5-SMC6 complex component	11664	0.22
chr7_117472401_117472742	15.11	Xylt1	xylosyltransferase 1	2921	0.39
chr1_42703489_42704501	15.11	Pantr2	POU domain, class 3, transcription factor 3 adjacent noncoding transcript 2	4057	0.16
chr13_83714747_83715651	15.08	C130071C03Rik	RIKEN cDNA C130071C03 gene	6182	0.14
chr13_95995367_95995681	15.05	Sv2c	synaptic vesicle glycoprotein 2c	5298	0.24
chr9_9263661_9263812	15.05	Gm16833	predicted gene, 16833	3053	0.29
chr7_79591873_79592800	14.99	Gm45169	predicted gene 45169	277	0.82
chr6_16316362_16316531	14.96	Gm3148	predicted gene 3148	78819	0.1
chr12_44839950_44840386	14.92	Gm15901	predicted gene 15901	83012	0.1
chr2_41093986_41094158	14.90	Gm13460	predicted gene 13460	95215	0.09
chr1_4970686_4970886	14.87	Gm16041	predicted gene 16041	71	0.97
chr18_81831298_81831489	14.86	Gm30454	predicted gene, 30454	18623	0.19
chr14_35112923_35113111	14.85	Gm49034	predicted gene, 49034	106421	0.07
chr1_157969609_157969781	14.85	Gm38256	predicted gene, 38256	29310	0.25
chr2_141955236_141955408	14.82	Fau-ps1	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived), pseudogene 1	116533	0.07
chr8_30924151_30924556	14.80	Gm45252	predicted gene 45252	79555	0.1
chr1_41605488_41605642	14.78	Gm28634	predicted gene 28634	76022	0.12
chr8_34326259_34326892	14.77	Gm4889	predicted gene 4889	1335	0.32
chr4_32325733_32325955	14.73	Bach2it1	BTB and CNC homology 2, intronic transcript 1	74083	0.1
chr8_41054736_41055125	14.73	Mtus1	mitochondrial tumor suppressor 1	136	0.94
chr10_33624726_33624916	14.72	Clvs2	clavesin 2	52	0.9
chr6_12117902_12118084	14.68	Gm6578	predicted gene 6578	8410	0.23
chr18_78455374_78455574	14.67	4931439C15Rik	RIKEN cDNA 4931439C15 gene	21404	0.24
chr12_12684520_12684723	14.67	Gm27952	predicted gene, 27952	2003	0.29
chr12_33035439_33035619	14.65	Cdhr3	cadherin-related family member 3	17457	0.14
chr3_47668909_47669138	14.61	Gm2229	predicted gene 2229	208685	0.03
chr14_85508520_85508926	14.55	Gm9264	predicted gene 9264	29697	0.26
chr2_181766899_181767258	14.55	Myt1	myelin transcription factor 1	36	0.97
chr8_49243134_49243285	14.53	Gm45832	predicted gene 45832	11240	0.28
chr17_84749518_84749672	14.52	Lrpprc	leucine-rich PPR-motif containing	1667	0.35
chr4_20401022_20401283	14.50	Gm11873	predicted gene 11873	10056	0.28
chr15_85463386_85463550	14.49	7530416G11Rik	RIKEN cDNA 7530416G11 gene	39759	0.14
chr4_71230174_71230407	14.44	Gm11229	predicted gene 11229	55652	0.15
chr6_15397521_15397861	14.44	Gm25470	predicted gene, 25470	7290	0.26
chr17_8368820_8369004	14.44	T2	brachyury 2	3484	0.15
chr5_36174716_36175143	14.42	Psapl1	prosaposin-like 1	29092	0.21
chr5_4812167_4812377	14.42	Gm44483	predicted gene, 44483	9815	0.12
chr4_21665942_21666298	14.40	Gm11876	predicted gene 11876	4920	0.2
chr11_11014435_11014603	14.35	Vwc2	von Willebrand factor C domain containing 2	99704	0.08
chr2_41471881_41472032	14.29	Lrp1b	low density lipoprotein-related protein 1B	317122	0.01
chrX_47124254_47124450	14.27	Gm14609	predicted gene 14609	256982	0.02
chr15_37787189_37787357	14.25	Ncald	neurocalcin delta	4727	0.2
chr12_37978926_37979077	14.24	Dgkb	diacylglycerol kinase, beta	38713	0.17
chr1_138500251_138500631	14.24	Gm28501	predicted gene 28501	15174	0.2
chr9_23378360_23378672	14.24	Bmper	BMP-binding endothelial regulator	4584	0.36
chr2_93957909_93958083	14.24	Gm13889	predicted gene 13889	795	0.55
chrX_60545622_60545821	14.22	Gm715	predicted gene 715	2298	0.23
chr5_81359614_81359973	14.21	Adgrl3	adhesion G protein-coupled receptor L3	49768	0.18
chr2_21270050_21270364	14.20	Gm13378	predicted gene 13378	26102	0.17
chr18_23036938_23037296	14.17	Nol4	nucleolar protein 4	1539	0.55
chr16_67175484_67175665	14.17	Gm49640	predicted gene, 49640	62776	0.16
chr13_63985759_63985962	14.11	Gm7695	predicted gene 7695	39339	0.14
chrX_42343522_42343895	14.11	Gm14619	predicted gene 14619	3804	0.34
chr13_20609106_20609281	14.10	Gm47721	predicted gene, 47721	36564	0.17
chr9_37114956_37115270	14.07	Gm48716	predicted gene, 48716	3543	0.18
chr14_77406295_77406469	14.06	Enox1	ecto-NOX disulfide-thiol exchanger 1	25736	0.17
chr16_59854456_59854822	14.05	Epha6	Eph receptor A6	151082	0.04
chr18_25548818_25548982	13.97	Celf4	CUGBP, Elav-like family member 4	47661	0.16
chr1_179106714_179107112	13.92	Smyd3	SET and MYND domain containing 3	117568	0.06
chr13_76810564_76810975	13.89	Mctp1	multiple C2 domains, transmembrane 1	14438	0.26
chr1_74103754_74104304	13.89	Tns1	tensin 1	5353	0.18
chr10_66546751_66546933	13.87	Gm22594	predicted gene, 22594	63289	0.12
chr13_78181182_78181614	13.81	Gm38604	predicted gene, 38604	1761	0.26
chr11_32019966_32020621	13.79	Nsg2	neuron specific gene family member 2	19791	0.19
chr5_133821082_133821288	13.79	Gm7902	predicted gene 7902	21334	0.25
chr3_26145444_26145600	13.79	Nlgn1	neuroligin 1	7785	0.32
chr4_148327377_148327851	13.75	Gm13206	predicted gene 13206	20761	0.14
chr7_76789063_76789214	13.74	Gm45210	predicted gene 45210	89421	0.1
chr4_70811006_70811333	13.73	Gm11227	predicted gene 11227	261504	0.02
chr2_101979368_101979730	13.72	Gm13919	predicted gene 13919	60080	0.11
chr15_74194149_74194481	13.72	Gm15387	predicted gene 15387	99982	0.07
chr11_26437833_26438032	13.67	Gm12713	predicted gene 12713	28725	0.18
chr13_26657396_26657590	13.61	Gm47883	predicted gene, 47883	23200	0.23
chr17_88764144_88764434	13.57	Lhcgr	luteinizing hormone/choriogonadotropin receptor	9767	0.24
chr9_41378019_41378386	13.55	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	1641	0.36
chr19_21781727_21782179	13.55	Cemip2	cell migration inducing hyaluronidase 2	3565	0.26
chr2_142362908_142363300	13.54	Macrod2	mono-ADP ribosylhydrolase 2	186497	0.03
chr10_43106136_43106524	13.54	Gm29245	predicted gene 29245	47886	0.11
chr5_9339805_9340127	13.53	Gm15733	predicted gene 15733	13793	0.19
chr10_87501180_87501623	13.51	Gm48120	predicted gene, 48120	6461	0.19
chr2_57523169_57523407	13.50	Gm13531	predicted gene 13531	97579	0.07
chr3_30153909_30154137	13.49	Gm38066	predicted gene, 38066	7863	0.21
chr3_83985537_83985711	13.48	Tmem131l	transmembrane 131 like	17396	0.24
chr5_106577659_106577832	13.47	Gm29464	predicted gene 29464	2870	0.18
chr17_63807674_63808197	13.46	Fer	fer (fms/fps related) protein kinase	55127	0.13
chr12_77991634_77991958	13.43	Gm8219	predicted gene 8219	172214	0.03
chr4_111686063_111686242	13.41	Spata6	spermatogenesis associated 6	33832	0.2
chrX_130820134_130820324	13.36	Gm26209	predicted gene, 26209	67549	0.13
chr6_111844651_111844869	13.30	Gm22093	predicted gene, 22093	241508	0.02
chr4_54329031_54329272	13.29	Gm12469	predicted gene 12469	93275	0.09
chr14_75236389_75236560	13.28	Cpb2	carboxypeptidase B2 (plasma)	5813	0.15
chr1_52079807_52079978	13.27	Gm28177	predicted gene 28177	2631	0.2
chr11_88240584_88240997	13.27	Gm38534	predicted gene, 38534	12578	0.16
chr7_96595597_96595770	13.23	Gm15414	predicted gene 15414	33386	0.19
chr3_127652402_127652663	13.16	Neurog2	neurogenin 2	19397	0.11
chr14_22679666_22680655	13.14	Lrmda	leucine rich melanocyte differentiation associated	83647	0.09
chr6_137699415_137699798	13.13	Strap	serine/threonine kinase receptor associated protein	35472	0.16
chr15_84531439_84531771	13.12	Rtl6	retrotransposon Gag like 6	26218	0.18
chr5_45008044_45008269	13.12	Gm10205	predicted gene 10205	23914	0.2
chr5_103335878_103336033	13.12	Gm42619	predicted gene 42619	8017	0.16
chr1_3094927_3095127	13.12	Gm26206	predicted gene, 26206	6989	0.25
chr2_72426764_72427187	13.04	Cdca7	cell division cycle associated 7	49184	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Alx4

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.0	23.9	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
6.8	27.3	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
6.6	19.9	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
5.0	15.0	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
4.8	4.8	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
4.6	18.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
4.0	12.1	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
3.6	25.2	GO:0016198	axon choice point recognition(GO:0016198)
3.3	9.9	GO:0072235	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
3.1	3.1	GO:0048880	sensory system development(GO:0048880)
3.0	33.4	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
3.0	18.1	GO:0098598	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
2.9	8.8	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
2.8	8.5	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
2.8	8.3	GO:0032289	central nervous system myelin formation(GO:0032289)
2.7	8.2	GO:0060178	regulation of exocyst localization(GO:0060178)
2.7	8.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
2.6	23.3	GO:0050957	equilibrioception(GO:0050957)
2.6	7.8	GO:0007412	axon target recognition(GO:0007412)
2.4	21.7	GO:0021796	cerebral cortex regionalization(GO:0021796)
2.4	7.2	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
2.3	16.0	GO:0042118	endothelial cell activation(GO:0042118)
2.3	4.5	GO:0003358	noradrenergic neuron development(GO:0003358)
2.2	8.8	GO:0060279	positive regulation of ovulation(GO:0060279)
2.1	6.2	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
2.1	10.4	GO:0061669	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
2.1	6.2	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
2.0	6.0	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
2.0	7.8	GO:0046959	habituation(GO:0046959)
2.0	7.8	GO:0030091	protein repair(GO:0030091)
1.9	7.8	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
1.9	9.6	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636)
1.9	5.7	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
1.9	3.8	GO:2000974	negative regulation of pro-B cell differentiation(GO:2000974)
1.9	3.8	GO:0008090	retrograde axonal transport(GO:0008090)
1.9	15.2	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
1.9	1.9	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
1.9	5.6	GO:0046684	response to pyrethroid(GO:0046684)
1.8	5.5	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
1.8	5.5	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
1.8	7.3	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
1.8	5.4	GO:0089700	protein kinase D signaling(GO:0089700)
1.8	7.1	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
1.7	10.4	GO:0048681	negative regulation of axon regeneration(GO:0048681)
1.7	6.8	GO:1902669	positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
1.7	3.3	GO:0031223	auditory behavior(GO:0031223)
1.7	5.0	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
1.6	6.5	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
1.6	1.6	GO:2000981	negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
1.6	8.0	GO:0016576	histone dephosphorylation(GO:0016576)
1.6	4.7	GO:0045423	granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423)
1.6	6.2	GO:0006537	glutamate biosynthetic process(GO:0006537)
1.6	7.8	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
1.5	21.4	GO:0003334	keratinocyte development(GO:0003334)
1.5	6.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
1.5	7.5	GO:2000481	positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
1.5	1.5	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
1.5	4.4	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
1.5	7.4	GO:0021631	optic nerve morphogenesis(GO:0021631)
1.5	5.8	GO:0097476	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
1.5	7.3	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
1.4	26.1	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
1.4	24.2	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
1.4	6.9	GO:1903887	motile primary cilium assembly(GO:1903887)
1.4	4.1	GO:0001661	conditioned taste aversion(GO:0001661)
1.3	4.0	GO:0060235	lens induction in camera-type eye(GO:0060235)
1.3	2.6	GO:0060825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.3	2.6	GO:0051964	negative regulation of synapse assembly(GO:0051964)
1.3	2.6	GO:0002121	inter-male aggressive behavior(GO:0002121)
1.3	2.5	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.3	3.8	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
1.3	3.8	GO:2000821	regulation of grooming behavior(GO:2000821)
1.2	3.7	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
1.2	8.5	GO:2001224	positive regulation of neuron migration(GO:2001224)
1.2	15.8	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
1.2	1.2	GO:0061642	chemoattraction of axon(GO:0061642)
1.2	3.5	GO:0006562	proline catabolic process(GO:0006562)
1.2	5.9	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
1.2	3.5	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
1.2	5.9	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
1.1	3.4	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
1.1	5.7	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
1.1	6.8	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
1.1	3.4	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
1.1	3.3	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.1	5.6	GO:0048852	diencephalon morphogenesis(GO:0048852)
1.1	3.3	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
1.1	4.4	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
1.1	3.3	GO:1990123	L-glutamate(1-) import into cell(GO:1903802) L-glutamate import into cell(GO:1990123)
1.1	3.2	GO:0002767	immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
1.1	3.2	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
1.0	2.1	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.0	3.1	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
1.0	11.2	GO:0021871	forebrain regionalization(GO:0021871)
1.0	2.0	GO:0060618	nipple development(GO:0060618)
1.0	6.1	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
1.0	5.0	GO:0007256	activation of JNKK activity(GO:0007256)
1.0	4.0	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
1.0	4.0	GO:0023041	neuronal signal transduction(GO:0023041)
1.0	2.9	GO:0097105	presynaptic membrane assembly(GO:0097105)
1.0	2.9	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.0	1.9	GO:1903818	positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.9	1.9	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.9	4.7	GO:0014028	notochord formation(GO:0014028)
0.9	3.7	GO:0021979	hypothalamus cell differentiation(GO:0021979)
0.9	4.6	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.9	2.8	GO:0021554	optic nerve development(GO:0021554)
0.9	1.8	GO:0035262	gonad morphogenesis(GO:0035262)
0.9	6.4	GO:0060179	male mating behavior(GO:0060179)
0.9	4.5	GO:0035881	amacrine cell differentiation(GO:0035881)
0.9	2.7	GO:0042126	nitrate metabolic process(GO:0042126)
0.9	2.7	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.9	7.1	GO:0060539	diaphragm development(GO:0060539)
0.9	2.7	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.9	3.5	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.9	6.2	GO:0071625	vocalization behavior(GO:0071625)
0.9	2.6	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.9	6.9	GO:0046069	cGMP catabolic process(GO:0046069)
0.8	2.5	GO:0008355	olfactory learning(GO:0008355)
0.8	10.1	GO:0010842	retina layer formation(GO:0010842)
0.8	2.5	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.8	2.5	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.8	2.4	GO:0072051	juxtaglomerular apparatus development(GO:0072051)
0.8	5.7	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.8	0.8	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.8	3.2	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.8	2.4	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.8	1.6	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.8	4.7	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.8	8.6	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.8	1.6	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.8	2.3	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.8	0.8	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.8	2.3	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.8	3.1	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.8	2.3	GO:0071288	cellular response to mercury ion(GO:0071288)
0.8	3.0	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.7	3.0	GO:0072257	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.7	6.7	GO:0060736	prostate gland growth(GO:0060736)
0.7	5.2	GO:0071732	cellular response to nitric oxide(GO:0071732)
0.7	2.2	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.7	1.5	GO:0060005	vestibular reflex(GO:0060005)
0.7	3.7	GO:0071371	cellular response to gonadotropin stimulus(GO:0071371)
0.7	2.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.7	2.2	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.7	6.5	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.7	2.2	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.7	3.6	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.7	1.4	GO:1903367	regulation of fear response(GO:1903365) positive regulation of fear response(GO:1903367) regulation of behavioral fear response(GO:2000822) positive regulation of behavioral fear response(GO:2000987)
0.7	1.4	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.7	12.1	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.7	2.8	GO:0035627	ceramide transport(GO:0035627)
0.7	3.5	GO:0036289	peptidyl-serine autophosphorylation(GO:0036289)
0.7	1.4	GO:0000101	sulfur amino acid transport(GO:0000101)
0.7	3.5	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.7	1.4	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.7	2.1	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.7	5.5	GO:0070253	somatostatin secretion(GO:0070253)
0.7	2.0	GO:0090135	actin filament branching(GO:0090135)
0.7	4.7	GO:0006108	malate metabolic process(GO:0006108)
0.7	2.0	GO:0030070	insulin processing(GO:0030070)
0.7	2.7	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.7	5.3	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.7	2.7	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.7	2.7	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.7	2.6	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.7	2.6	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.6	1.9	GO:0097195	pilomotor reflex(GO:0097195)
0.6	1.9	GO:0015888	thiamine transport(GO:0015888)
0.6	1.9	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.6	5.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.6	3.2	GO:0050861	positive regulation of B cell receptor signaling pathway(GO:0050861)
0.6	1.3	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.6	6.3	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.6	1.9	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.6	3.1	GO:0090037	positive regulation of protein kinase C signaling(GO:0090037)
0.6	2.5	GO:0061743	motor learning(GO:0061743)
0.6	1.2	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.6	1.2	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.6	0.6	GO:0097466	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.6	1.8	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.6	1.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.6	1.2	GO:0042322	negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322)
0.6	1.8	GO:0001927	exocyst assembly(GO:0001927)
0.6	1.8	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.6	1.2	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.6	4.7	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.6	4.6	GO:0086036	regulation of cardiac muscle cell membrane potential(GO:0086036)
0.6	2.9	GO:0019532	oxalate transport(GO:0019532)
0.6	2.3	GO:0022038	corpus callosum development(GO:0022038)
0.6	7.5	GO:0042670	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.6	2.9	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.6	11.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.6	3.4	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.6	1.1	GO:0014029	neural crest formation(GO:0014029)
0.6	1.7	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.6	7.3	GO:0016082	synaptic vesicle priming(GO:0016082)
0.6	5.0	GO:0097120	receptor localization to synapse(GO:0097120)
0.6	0.6	GO:0006524	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.6	1.1	GO:0031296	B cell costimulation(GO:0031296)
0.6	1.1	GO:0033693	neurofilament bundle assembly(GO:0033693)
0.6	0.6	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.5	3.8	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.5	1.1	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.5	1.1	GO:0090427	activation of meiosis(GO:0090427)
0.5	3.2	GO:0060581	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.5	40.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.5	4.8	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.5	0.5	GO:0021524	visceral motor neuron differentiation(GO:0021524)
0.5	5.8	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.5	7.9	GO:2001222	regulation of neuron migration(GO:2001222)
0.5	1.0	GO:0003357	noradrenergic neuron differentiation(GO:0003357)
0.5	1.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.5	0.5	GO:1902996	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.5	1.5	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5	1.0	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.5	5.5	GO:0003407	neural retina development(GO:0003407)
0.5	2.0	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.5	8.3	GO:0060997	dendritic spine morphogenesis(GO:0060997)
0.5	1.0	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.5	4.2	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.5	1.9	GO:0070126	mitochondrial translational termination(GO:0070126)
0.5	1.9	GO:0035912	dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.5	2.8	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.5	1.8	GO:0090148	membrane fission(GO:0090148)
0.5	1.4	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.5	5.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.5	0.5	GO:2001027	negative regulation of endothelial cell chemotaxis(GO:2001027)
0.5	0.5	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.5	0.9	GO:0010963	regulation of L-arginine import(GO:0010963)
0.5	0.5	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.5	1.4	GO:0046077	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.4	1.3	GO:2000617	positive regulation of histone H3-K9 acetylation(GO:2000617)
0.4	2.7	GO:0060134	prepulse inhibition(GO:0060134)
0.4	0.9	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.4	1.3	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.4	1.8	GO:0018343	protein farnesylation(GO:0018343)
0.4	2.6	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.4	1.8	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.4	1.3	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.4	1.7	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.4	1.3	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.4	1.3	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.4	1.7	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.4	3.8	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.4	1.2	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.4	2.9	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.4	0.8	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.4	1.2	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.4	0.4	GO:0097090	presynaptic membrane organization(GO:0097090)
0.4	0.8	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.4	2.0	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.4	1.2	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.4	0.4	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.4	1.2	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4	3.9	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.4	1.6	GO:0006642	triglyceride mobilization(GO:0006642)
0.4	0.8	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.4	17.8	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.4	4.2	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.4	1.5	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.4	1.5	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.4	1.5	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.4	2.2	GO:1901077	regulation of relaxation of muscle(GO:1901077)
0.4	1.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.4	1.5	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.4	1.1	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.4	2.2	GO:0099515	actin filament-based transport(GO:0099515)
0.4	1.5	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.4	7.6	GO:0006376	mRNA splice site selection(GO:0006376)
0.4	1.1	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.4	1.1	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.4	1.8	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.4	0.4	GO:0048069	eye pigmentation(GO:0048069)
0.4	0.7	GO:0051036	regulation of endosome size(GO:0051036)
0.4	1.1	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.4	1.8	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.4	1.1	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.3	1.4	GO:0070365	hepatocyte differentiation(GO:0070365)
0.3	3.1	GO:0001964	startle response(GO:0001964)
0.3	1.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.3	4.4	GO:0030318	melanocyte differentiation(GO:0030318)
0.3	0.3	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3	2.0	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.3	1.3	GO:0097343	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.3	0.7	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.3	1.0	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.3	1.7	GO:0001504	neurotransmitter uptake(GO:0001504)
0.3	1.0	GO:0072092	ureteric bud invasion(GO:0072092)
0.3	1.3	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.3	0.7	GO:0042723	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.3	1.6	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.3	0.7	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.3	2.0	GO:0097062	dendritic spine maintenance(GO:0097062)
0.3	2.3	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.3	0.3	GO:0071374	cellular response to parathyroid hormone stimulus(GO:0071374)
0.3	0.6	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.3	0.3	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459)
0.3	0.3	GO:0035983	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.3	1.6	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.3	0.6	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.3	3.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.3	0.9	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.3	0.9	GO:0009233	menaquinone metabolic process(GO:0009233)
0.3	0.6	GO:1905005	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005)
0.3	0.6	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.3	0.6	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.3	1.2	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.3	0.9	GO:0030432	peristalsis(GO:0030432)
0.3	0.9	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.3	0.6	GO:0014724	regulation of twitch skeletal muscle contraction(GO:0014724)
0.3	0.9	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661)
0.3	0.6	GO:0034091	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.3	0.9	GO:0002568	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.3	1.2	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3	0.9	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.3	1.2	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.3	0.9	GO:0071675	regulation of mononuclear cell migration(GO:0071675)
0.3	0.6	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.3	1.4	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406)
0.3	0.6	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.3	0.6	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.3	6.9	GO:0051931	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.3	0.5	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.3	0.8	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.3	4.3	GO:0008053	mitochondrial fusion(GO:0008053)
0.3	1.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.3	1.9	GO:0031643	positive regulation of myelination(GO:0031643)
0.3	4.3	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.3	2.4	GO:0071435	potassium ion export(GO:0071435)
0.3	0.3	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209)
0.3	0.3	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.3	3.9	GO:0008045	motor neuron axon guidance(GO:0008045)
0.3	0.5	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.3	1.5	GO:0035641	locomotory exploration behavior(GO:0035641)
0.3	0.8	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.3	0.5	GO:0072173	metanephric tubule morphogenesis(GO:0072173)
0.3	1.0	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627) mitochondrial protein processing(GO:0034982)
0.3	0.5	GO:0071873	response to norepinephrine(GO:0071873)
0.2	0.7	GO:1902570	protein localization to nucleolus(GO:1902570) regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.2	1.7	GO:0090036	regulation of protein kinase C signaling(GO:0090036)
0.2	2.0	GO:1904871	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.2	1.5	GO:0001780	neutrophil homeostasis(GO:0001780)
0.2	2.0	GO:0050908	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.2	2.4	GO:0017121	phospholipid scrambling(GO:0017121)
0.2	0.2	GO:0070571	negative regulation of neuron projection regeneration(GO:0070571)
0.2	0.2	GO:0010749	regulation of nitric oxide mediated signal transduction(GO:0010749)
0.2	1.9	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.2	1.2	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.2	0.2	GO:0034238	macrophage fusion(GO:0034238)
0.2	1.7	GO:0006450	regulation of translational fidelity(GO:0006450)
0.2	2.1	GO:0090161	Golgi ribbon formation(GO:0090161)
0.2	1.8	GO:0034650	cortisol metabolic process(GO:0034650)
0.2	0.7	GO:0051665	membrane raft localization(GO:0051665)
0.2	0.7	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2	0.7	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.2	0.4	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	1.6	GO:0042989	sequestering of actin monomers(GO:0042989)
0.2	0.7	GO:0006177	GMP biosynthetic process(GO:0006177)
0.2	1.1	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.2	1.3	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.2	0.2	GO:0021586	pons maturation(GO:0021586)
0.2	0.6	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.2	0.4	GO:0086103	G-protein coupled receptor signaling pathway involved in heart process(GO:0086103)
0.2	0.6	GO:0002930	trabecular meshwork development(GO:0002930)
0.2	0.4	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.2	0.8	GO:0018202	peptidyl-histidine modification(GO:0018202)
0.2	2.8	GO:0045879	negative regulation of smoothened signaling pathway(GO:0045879)
0.2	0.6	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.2	0.6	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.2	2.1	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.2	0.6	GO:0043615	astrocyte cell migration(GO:0043615)
0.2	0.4	GO:1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.2	1.4	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2	1.0	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2	0.4	GO:0070431	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.2	3.8	GO:0006270	DNA replication initiation(GO:0006270)
0.2	2.4	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.2	3.6	GO:0001754	eye photoreceptor cell differentiation(GO:0001754) eye photoreceptor cell development(GO:0042462)
0.2	0.6	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.2	0.6	GO:0021854	hypothalamus development(GO:0021854)
0.2	0.2	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.2	1.4	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.2	0.4	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.2	1.4	GO:1902260	negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.2	2.5	GO:0034587	piRNA metabolic process(GO:0034587)
0.2	0.6	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.2	0.8	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.2	0.4	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.2	0.9	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.2	0.2	GO:0046098	guanine metabolic process(GO:0046098)
0.2	1.3	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.2	0.9	GO:0098787	mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2	0.2	GO:0070070	proton-transporting V-type ATPase complex assembly(GO:0070070)
0.2	0.6	GO:0032304	negative regulation of icosanoid secretion(GO:0032304)
0.2	0.2	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2	0.7	GO:0071225	cellular response to muramyl dipeptide(GO:0071225)
0.2	0.7	GO:0071763	nuclear membrane organization(GO:0071763)
0.2	0.5	GO:0090343	positive regulation of cell aging(GO:0090343)
0.2	2.0	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.2	0.9	GO:0001302	replicative cell aging(GO:0001302)
0.2	0.2	GO:0006543	glutamine catabolic process(GO:0006543)
0.2	0.2	GO:0046083	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.2	0.3	GO:0097119	postsynaptic density protein 95 clustering(GO:0097119)
0.2	0.2	GO:0060278	regulation of ovulation(GO:0060278)
0.2	1.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.2	0.2	GO:1901859	negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.2	0.9	GO:0048496	maintenance of organ identity(GO:0048496)
0.2	0.5	GO:0039530	MDA-5 signaling pathway(GO:0039530)
0.2	0.7	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.2	0.5	GO:0003348	cardiac endothelial cell differentiation(GO:0003348)
0.2	1.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	1.0	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.2	1.4	GO:0046697	decidualization(GO:0046697)
0.2	1.2	GO:2000254	regulation of male germ cell proliferation(GO:2000254)
0.2	0.5	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.2	1.2	GO:0002329	pre-B cell differentiation(GO:0002329)
0.2	0.7	GO:0030578	PML body organization(GO:0030578)
0.2	0.7	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.2	0.5	GO:0007525	somatic muscle development(GO:0007525)
0.2	0.5	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.2	0.5	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.2	1.1	GO:1990118	sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2	0.5	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2	0.3	GO:0043576	regulation of respiratory gaseous exchange(GO:0043576)
0.2	0.2	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.2	1.1	GO:0014820	tonic smooth muscle contraction(GO:0014820)
0.2	6.5	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.2	0.9	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.2	0.5	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.2	0.9	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.2	0.3	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1	0.3	GO:0045472	response to ether(GO:0045472)
0.1	0.4	GO:2000118	regulation of sodium-dependent phosphate transport(GO:2000118)
0.1	1.0	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.1	0.3	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.3	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.1	0.3	GO:0015755	fructose transport(GO:0015755)
0.1	0.6	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.1	0.6	GO:0006517	protein deglycosylation(GO:0006517)
0.1	0.4	GO:0071492	cellular response to UV-A(GO:0071492)
0.1	0.3	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.1	0.1	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.1	1.6	GO:0002093	auditory receptor cell morphogenesis(GO:0002093)
0.1	0.3	GO:2000508	regulation of dendritic cell chemotaxis(GO:2000508)
0.1	0.4	GO:0006553	lysine metabolic process(GO:0006553)
0.1	0.4	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	0.3	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.1	0.4	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.1	0.3	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	1.0	GO:0030643	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1	3.7	GO:0031424	keratinization(GO:0031424)
0.1	0.1	GO:0043366	beta selection(GO:0043366)
0.1	0.3	GO:0072318	clathrin coat disassembly(GO:0072318)
0.1	0.1	GO:0010996	response to auditory stimulus(GO:0010996)
0.1	0.4	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.1	2.9	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.1	0.1	GO:0009826	unidimensional cell growth(GO:0009826)
0.1	3.6	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	0.1	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.1	0.3	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1	0.6	GO:0046110	xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.1	0.4	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1	2.0	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1	0.5	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.1	0.3	GO:0051582	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1	0.4	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1	0.1	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.1	1.0	GO:0042448	progesterone metabolic process(GO:0042448)
0.1	0.5	GO:0071034	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1	0.8	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.1	0.8	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.1	0.1	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.1	0.1	GO:1903795	regulation of inorganic anion transmembrane transport(GO:1903795)
0.1	0.2	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.1	0.1	GO:1904833	regulation of superoxide dismutase activity(GO:1901668) positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.1	0.2	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1	0.4	GO:0043313	regulation of neutrophil degranulation(GO:0043313)
0.1	1.0	GO:0035428	hexose transmembrane transport(GO:0035428)
0.1	0.3	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.1	0.3	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1	0.3	GO:1902915	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1	0.9	GO:0045779	negative regulation of bone resorption(GO:0045779)
0.1	0.3	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.1	0.4	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.1	0.1	GO:0006971	hypotonic response(GO:0006971)
0.1	0.7	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.1	0.2	GO:0070340	detection of bacterial lipopeptide(GO:0070340)
0.1	0.3	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	1.1	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.1	1.3	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.1	0.2	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1	0.1	GO:0006533	aspartate catabolic process(GO:0006533)
0.1	1.2	GO:0003016	respiratory system process(GO:0003016)
0.1	0.4	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.1	0.8	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	0.2	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1	1.0	GO:0009404	toxin metabolic process(GO:0009404)
0.1	0.3	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1	0.1	GO:1902065	response to L-glutamate(GO:1902065)
0.1	0.2	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.1	0.5	GO:0071420	cellular response to histamine(GO:0071420)
0.1	0.2	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.1	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	1.0	GO:0016486	peptide hormone processing(GO:0016486)
0.1	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1	0.3	GO:0035247	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.1	0.8	GO:0070570	regulation of neuron projection regeneration(GO:0070570)
0.1	1.3	GO:0007616	long-term memory(GO:0007616)
0.1	0.2	GO:0090383	phagosome acidification(GO:0090383)
0.1	0.3	GO:0032512	regulation of protein phosphatase type 2B activity(GO:0032512)
0.1	0.6	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.1	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.2	GO:0050705	regulation of interleukin-1 alpha secretion(GO:0050705)
0.1	0.2	GO:0042505	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.1	1.5	GO:0021954	central nervous system neuron development(GO:0021954)
0.1	0.3	GO:0002254	kinin cascade(GO:0002254)
0.1	0.2	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1	1.2	GO:0030497	fatty acid elongation(GO:0030497)
0.1	0.3	GO:0072530	purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.1	0.3	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.1	0.1	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.1	0.3	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1	0.3	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.1	1.2	GO:0035855	megakaryocyte development(GO:0035855)
0.1	0.2	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.1	0.1	GO:0032762	mast cell cytokine production(GO:0032762) regulation of mast cell cytokine production(GO:0032763)
0.1	0.2	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.1	0.4	GO:2000811	negative regulation of anoikis(GO:2000811)
0.1	0.1	GO:2001023	regulation of response to drug(GO:2001023)
0.1	0.4	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.2	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.1	0.3	GO:0032570	response to progesterone(GO:0032570)
0.1	0.1	GO:0071692	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.1	0.2	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.3	GO:0032048	cardiolipin metabolic process(GO:0032048)
0.1	3.0	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.1	0.7	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1	0.1	GO:0035483	gastric emptying(GO:0035483)
0.1	0.1	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.1	1.1	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1	0.1	GO:0035826	rubidium ion transport(GO:0035826)
0.1	0.3	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.1	0.3	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.1	0.9	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	0.1	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.1	0.5	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.1	0.1	GO:0042891	antibiotic transport(GO:0042891)
0.1	0.2	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
0.1	0.2	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1	0.1	GO:1903334	positive regulation of protein folding(GO:1903334)
0.1	0.2	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.5	GO:2000291	regulation of myoblast proliferation(GO:2000291)
0.1	0.4	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.1	0.1	GO:0060467	negative regulation of fertilization(GO:0060467)
0.1	0.1	GO:0010579	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.1	0.3	GO:0042078	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	0.5	GO:2000269	regulation of fibroblast apoptotic process(GO:2000269)
0.1	0.2	GO:0035640	exploration behavior(GO:0035640)
0.1	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.1	0.6	GO:0001963	synaptic transmission, dopaminergic(GO:0001963)
0.1	0.3	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.1	0.1	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655) phosphatidylglycerol metabolic process(GO:0046471)
0.1	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.1	0.2	GO:0046469	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.1	0.1	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.1	0.1	GO:1901529	positive regulation of anion channel activity(GO:1901529)
0.1	0.5	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1	0.1	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.1	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.1	0.4	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.1	0.8	GO:0036465	synaptic vesicle recycling(GO:0036465)
0.1	0.1	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.1	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.1	1.2	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.2	GO:1903333	regulation of protein folding(GO:1903332) negative regulation of protein folding(GO:1903333)
0.1	0.1	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1	0.2	GO:0000054	ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.1	0.3	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.1	0.2	GO:0014901	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.1	0.1	GO:0002666	positive regulation of T cell tolerance induction(GO:0002666)
0.1	0.1	GO:2000484	positive regulation of interleukin-8 secretion(GO:2000484)
0.0	0.2	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.1	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.0	GO:0061156	pulmonary artery morphogenesis(GO:0061156)
0.0	0.1	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.0	0.2	GO:0015780	nucleotide-sugar transport(GO:0015780) pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.2	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.0	GO:0003099	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.0	GO:2000619	regulation of histone H4-K16 acetylation(GO:2000618) negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.2	GO:0019732	antifungal humoral response(GO:0019732)
0.0	0.4	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.3	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	1.1	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.0	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.0	GO:0031133	regulation of axon diameter(GO:0031133)
0.0	0.1	GO:0003181	atrioventricular valve morphogenesis(GO:0003181)
0.0	0.0	GO:0021559	trigeminal nerve development(GO:0021559)
0.0	0.1	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.0	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.0	0.1	GO:0035469	determination of pancreatic left/right asymmetry(GO:0035469)
0.0	0.2	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0	0.0	GO:0070162	adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.0	0.1	GO:0060729	intestinal epithelial structure maintenance(GO:0060729)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.2	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.2	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.0	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.0	0.3	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.2	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.0	GO:0035743	CD4-positive, alpha-beta T cell cytokine production(GO:0035743)
0.0	0.1	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.2	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.1	GO:0045113	regulation of integrin biosynthetic process(GO:0045113)
0.0	0.1	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.1	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	1.8	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.0	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.0	0.0	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.2	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.0	0.1	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.1	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.1	GO:0071397	cellular response to cholesterol(GO:0071397)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.0	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.0	0.0	GO:0042473	outer ear morphogenesis(GO:0042473)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.3	GO:0048265	response to pain(GO:0048265)
0.0	0.0	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0	0.0	GO:0060018	astrocyte fate commitment(GO:0060018)
0.0	0.0	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.0	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.0	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.0	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.3	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.2	GO:0051532	regulation of NFAT protein import into nucleus(GO:0051532)
0.0	0.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.0	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.0	GO:0043382	positive regulation of memory T cell differentiation(GO:0043382)
0.0	0.1	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.0	0.1	GO:0015867	ATP transport(GO:0015867)
0.0	0.3	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.0	GO:0032621	interleukin-18 production(GO:0032621)
0.0	0.2	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.0	0.5	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.0	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.1	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.0	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.6	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.0	GO:0016095	polyprenol catabolic process(GO:0016095)
0.0	0.0	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.0	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0	0.3	GO:1901379	regulation of potassium ion transmembrane transport(GO:1901379)
0.0	0.0	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.0	0.1	GO:0000270	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
0.0	0.0	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.0	GO:0002051	osteoblast fate commitment(GO:0002051)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.9	11.7	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
2.3	11.3	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
2.0	7.9	GO:0044300	cerebellar mossy fiber(GO:0044300)
1.9	18.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
1.8	5.4	GO:0072534	perineuronal net(GO:0072534)
1.8	27.2	GO:0043196	varicosity(GO:0043196)
1.8	10.7	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
1.6	47.5	GO:0048786	presynaptic active zone(GO:0048786)
1.6	8.0	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
1.4	5.6	GO:0033010	paranodal junction(GO:0033010)
1.2	33.3	GO:0044295	axonal growth cone(GO:0044295)
1.1	4.4	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.0	3.0	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
1.0	11.8	GO:0032426	stereocilium tip(GO:0032426)
1.0	2.9	GO:1990812	growth cone filopodium(GO:1990812)
1.0	5.7	GO:0016012	sarcoglycan complex(GO:0016012)
1.0	25.7	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.9	5.6	GO:0032584	growth cone membrane(GO:0032584)
0.9	3.7	GO:0019815	B cell receptor complex(GO:0019815)
0.9	0.9	GO:0035838	growing cell tip(GO:0035838)
0.9	0.9	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.9	1.7	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.8	2.3	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.8	1.5	GO:0097441	basilar dendrite(GO:0097441)
0.8	6.1	GO:0042788	polysomal ribosome(GO:0042788)
0.8	9.2	GO:0043656	host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656)
0.7	8.8	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.7	23.4	GO:0042734	presynaptic membrane(GO:0042734)
0.7	2.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.6	6.4	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.6	0.6	GO:0097418	neurofibrillary tangle(GO:0097418)
0.6	5.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.6	2.5	GO:0043083	synaptic cleft(GO:0043083)
0.6	2.3	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.5	5.5	GO:0043194	axon initial segment(GO:0043194)
0.5	6.4	GO:0031045	dense core granule(GO:0031045)
0.5	2.1	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.5	4.1	GO:0035253	ciliary rootlet(GO:0035253)
0.5	31.4	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5	2.0	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.5	1.5	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.5	2.4	GO:0005683	U7 snRNP(GO:0005683)
0.5	7.2	GO:0031527	filopodium membrane(GO:0031527)
0.5	1.4	GO:0032280	symmetric synapse(GO:0032280)
0.5	10.7	GO:0043198	dendritic shaft(GO:0043198)
0.5	5.0	GO:0030061	mitochondrial crista(GO:0030061)
0.5	4.1	GO:0036156	inner dynein arm(GO:0036156)
0.5	1.8	GO:0051286	cell tip(GO:0051286)
0.5	3.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.4	2.2	GO:0089701	U2AF(GO:0089701)
0.4	6.9	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.4	6.7	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.4	1.2	GO:0097149	centralspindlin complex(GO:0097149)
0.4	3.3	GO:0030991	intraciliary transport particle A(GO:0030991)
0.4	1.6	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.4	1.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4	1.2	GO:0048179	activin receptor complex(GO:0048179)
0.4	3.4	GO:0060077	inhibitory synapse(GO:0060077)
0.4	0.7	GO:0033263	CORVET complex(GO:0033263)
0.4	4.4	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.3	54.5	GO:0060076	excitatory synapse(GO:0060076)
0.3	1.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.3	3.4	GO:0030673	axolemma(GO:0030673)
0.3	1.3	GO:1990716	axonemal central apparatus(GO:1990716)
0.3	1.2	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3	0.9	GO:0005594	collagen type IX trimer(GO:0005594)
0.3	0.6	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.3	7.3	GO:0032420	stereocilium(GO:0032420)
0.3	1.4	GO:0097433	dense body(GO:0097433)
0.3	1.6	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3	2.9	GO:0000346	transcription export complex(GO:0000346)
0.3	1.6	GO:0071437	invadopodium(GO:0071437)
0.3	6.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.3	1.0	GO:0097524	sperm plasma membrane(GO:0097524)
0.3	22.5	GO:0045211	postsynaptic membrane(GO:0045211)
0.3	1.0	GO:0071546	pi-body(GO:0071546)
0.2	1.2	GO:0071547	piP-body(GO:0071547)
0.2	2.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.2	3.7	GO:0042101	T cell receptor complex(GO:0042101)
0.2	0.9	GO:0070876	SOSS complex(GO:0070876)
0.2	3.1	GO:0070382	exocytic vesicle(GO:0070382)
0.2	0.2	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.2	0.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2	1.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.2	12.6	GO:0043195	terminal bouton(GO:0043195)
0.2	0.6	GO:0032437	cuticular plate(GO:0032437)
0.2	0.6	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.2	1.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.2	0.6	GO:0042585	germinal vesicle(GO:0042585)
0.2	0.6	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2	1.4	GO:0005577	fibrinogen complex(GO:0005577)
0.2	10.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.2	0.8	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.2	0.2	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.2	0.9	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.2	0.4	GO:1990909	Wnt signalosome(GO:1990909)
0.2	1.7	GO:0097542	ciliary tip(GO:0097542)
0.2	2.6	GO:0032809	neuronal cell body membrane(GO:0032809)
0.2	1.9	GO:0042555	MCM complex(GO:0042555)
0.2	0.2	GO:0044393	microspike(GO:0044393)
0.2	0.2	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.4	GO:0071797	LUBAC complex(GO:0071797)
0.1	0.1	GO:0031523	Myb complex(GO:0031523)
0.1	19.0	GO:0031225	anchored component of membrane(GO:0031225)
0.1	0.5	GO:0005883	neurofilament(GO:0005883)
0.1	0.3	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.1	0.5	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.1	0.7	GO:0070847	core mediator complex(GO:0070847)
0.1	0.6	GO:0000796	condensin complex(GO:0000796)
0.1	1.9	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.1	0.3	GO:0097543	ciliary inversin compartment(GO:0097543)
0.1	0.4	GO:0032009	early phagosome(GO:0032009)
0.1	0.4	GO:0005642	annulate lamellae(GO:0005642)
0.1	2.7	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	0.3	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.4	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.1	1.6	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.3	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.1	0.2	GO:1990923	PET complex(GO:1990923)
0.1	0.6	GO:0098642	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	4.6	GO:0001533	cornified envelope(GO:0001533)
0.1	0.4	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.5	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.1	0.3	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.1	3.3	GO:0005871	kinesin complex(GO:0005871)
0.1	0.3	GO:0000235	astral microtubule(GO:0000235)
0.1	0.3	GO:0001674	female germ cell nucleus(GO:0001674)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.2	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	0.2	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.1	0.7	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	0.2	GO:0000802	transverse filament(GO:0000802)
0.1	0.8	GO:0005652	nuclear lamina(GO:0005652)
0.1	0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	1.5	GO:0034451	centriolar satellite(GO:0034451)
0.1	0.8	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.1	GO:0017071	intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1	0.2	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1	0.5	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.6	GO:0044447	axoneme part(GO:0044447)
0.1	0.1	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.4	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.2	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.5	GO:0072546	ER membrane protein complex(GO:0072546)
0.0	0.3	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.5	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.0	GO:0018995	host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0	0.3	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.3	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	5.4	GO:0045202	synapse(GO:0045202)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.2	GO:0045277	respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.3	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.2	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.0	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.0	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.0	GO:0097209	epidermal lamellar body(GO:0097209)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.4	43.1	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
6.6	19.9	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
6.0	30.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
5.3	10.6	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
4.3	12.8	GO:0097109	neuroligin family protein binding(GO:0097109)
3.3	9.8	GO:0030158	protein xylosyltransferase activity(GO:0030158)
3.2	12.7	GO:0035727	lysophosphatidic acid binding(GO:0035727)
3.2	12.6	GO:0005030	neurotrophin receptor activity(GO:0005030)
2.9	8.7	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
2.6	7.7	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
1.9	5.8	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
1.9	5.6	GO:0008184	glycogen phosphorylase activity(GO:0008184)
1.9	13.0	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
1.8	5.5	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
1.8	7.3	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
1.8	5.4	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
1.7	8.3	GO:0005095	GTPase inhibitor activity(GO:0005095)
1.7	5.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
1.5	7.4	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.5	4.4	GO:0097108	hedgehog family protein binding(GO:0097108)
1.4	4.3	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
1.4	9.6	GO:0046790	virion binding(GO:0046790)
1.3	5.3	GO:0008502	melatonin receptor activity(GO:0008502)
1.3	5.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
1.2	3.7	GO:0050816	phosphothreonine binding(GO:0050816)
1.2	7.4	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
1.2	4.8	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.1	5.6	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
1.1	3.3	GO:0045503	dynein light chain binding(GO:0045503)
1.1	6.5	GO:0004385	guanylate kinase activity(GO:0004385)
1.0	23.9	GO:0071837	HMG box domain binding(GO:0071837)
1.0	3.1	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
1.0	8.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
1.0	5.0	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
1.0	7.8	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
1.0	12.6	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.0	2.9	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.9	2.8	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.9	3.7	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.9	3.6	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.9	0.9	GO:0004488	methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.9	16.9	GO:0030215	semaphorin receptor binding(GO:0030215)
0.9	8.0	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.9	2.6	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.9	3.5	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.9	1.7	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.9	2.6	GO:0071209	U7 snRNA binding(GO:0071209)
0.8	1.7	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.8	4.1	GO:0070728	leucine binding(GO:0070728)
0.8	5.8	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.8	2.5	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.8	0.8	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.8	2.5	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.8	4.9	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.8	12.0	GO:0016805	dipeptidase activity(GO:0016805)
0.8	2.4	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.8	1.6	GO:0097016	L27 domain binding(GO:0097016)
0.7	2.9	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.7	3.6	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.7	14.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.7	2.8	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.7	2.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.7	2.7	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.7	3.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.7	8.0	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.7	2.0	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.7	2.0	GO:0016015	morphogen activity(GO:0016015)
0.7	2.6	GO:0032051	clathrin light chain binding(GO:0032051)
0.7	3.9	GO:0045499	chemorepellent activity(GO:0045499)
0.6	7.1	GO:0030553	cGMP binding(GO:0030553)
0.6	12.3	GO:0017075	syntaxin-1 binding(GO:0017075)
0.6	3.1	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.6	2.4	GO:0097001	ceramide binding(GO:0097001)
0.6	1.8	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.6	3.6	GO:0008046	axon guidance receptor activity(GO:0008046)
0.6	1.8	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.6	7.7	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.6	5.2	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.6	1.7	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.6	1.7	GO:0051425	PTB domain binding(GO:0051425)
0.6	1.7	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.6	1.7	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.6	3.9	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.5	4.9	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.5	3.3	GO:0016421	CoA carboxylase activity(GO:0016421)
0.5	2.7	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.5	1.6	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5	3.2	GO:0008179	adenylate cyclase binding(GO:0008179)
0.5	2.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.5	2.6	GO:0048495	Roundabout binding(GO:0048495)
0.5	4.6	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.5	2.0	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.5	2.5	GO:0000182	rDNA binding(GO:0000182)
0.5	11.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.5	9.7	GO:0003785	actin monomer binding(GO:0003785)
0.5	10.5	GO:0052713	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.5	1.4	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.4	1.8	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.4	5.8	GO:0050811	GABA receptor binding(GO:0050811)
0.4	0.4	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.4	0.9	GO:0009374	biotin binding(GO:0009374)
0.4	2.6	GO:0032027	myosin light chain binding(GO:0032027)
0.4	4.7	GO:0005522	profilin binding(GO:0005522)
0.4	1.3	GO:0046428	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.4	1.2	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.4	2.0	GO:0042609	CD4 receptor binding(GO:0042609)
0.4	2.0	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.4	0.4	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4	5.2	GO:0017160	Ral GTPase binding(GO:0017160)
0.4	2.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.4	2.8	GO:0043495	protein anchor(GO:0043495)
0.4	4.8	GO:0004000	adenosine deaminase activity(GO:0004000)
0.4	0.8	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.4	2.4	GO:0050733	RS domain binding(GO:0050733)
0.4	7.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.4	1.9	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.4	1.5	GO:0070878	primary miRNA binding(GO:0070878)
0.4	3.8	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.4	1.1	GO:0030911	TPR domain binding(GO:0030911)
0.4	1.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.4	1.8	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.4	1.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.4	1.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.4	1.4	GO:0005042	netrin receptor activity(GO:0005042)
0.3	1.4	GO:0051434	BH3 domain binding(GO:0051434)
0.3	1.0	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.3	4.3	GO:0016917	GABA receptor activity(GO:0016917)
0.3	0.7	GO:0000405	bubble DNA binding(GO:0000405)
0.3	2.9	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.3	1.0	GO:0005502	11-cis retinal binding(GO:0005502)
0.3	0.3	GO:0008556	potassium-transporting ATPase activity(GO:0008556)
0.3	3.5	GO:0000146	microfilament motor activity(GO:0000146)
0.3	0.9	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.3	0.3	GO:0043426	MRF binding(GO:0043426)
0.3	1.5	GO:0001515	opioid peptide activity(GO:0001515)
0.3	6.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.3	0.6	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.3	0.9	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.3	1.5	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3	0.9	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.3	2.9	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.3	5.5	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.3	0.9	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.3	0.9	GO:0019961	interferon binding(GO:0019961)
0.3	2.8	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.3	0.8	GO:2001070	starch binding(GO:2001070)
0.3	0.6	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.3	0.8	GO:0004359	glutaminase activity(GO:0004359)
0.3	1.1	GO:0034235	GPI anchor binding(GO:0034235)
0.3	1.9	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.3	1.4	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.3	0.5	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.3	5.1	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3	1.9	GO:0004952	dopamine neurotransmitter receptor activity(GO:0004952)
0.3	1.3	GO:0004565	beta-galactosidase activity(GO:0004565)
0.3	6.3	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.3	3.1	GO:0035198	miRNA binding(GO:0035198)
0.3	1.0	GO:0033142	progesterone receptor binding(GO:0033142)
0.3	0.8	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.2	5.2	GO:0005537	mannose binding(GO:0005537)
0.2	0.7	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.2	1.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.2	3.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.2	1.2	GO:0071723	lipopeptide binding(GO:0071723)
0.2	1.0	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.2	14.7	GO:0051219	phosphoprotein binding(GO:0051219)
0.2	0.9	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.2	0.7	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.2	1.2	GO:0004985	opioid receptor activity(GO:0004985)
0.2	2.5	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	3.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2	2.2	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2	0.2	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2	0.6	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.2	5.6	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.2	0.6	GO:0019959	interleukin-8 binding(GO:0019959)
0.2	3.0	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2	0.6	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2	0.4	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.2	3.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.2	2.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.2	2.1	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.2	0.6	GO:0043823	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.2	2.7	GO:0070402	NADPH binding(GO:0070402)
0.2	0.4	GO:0034191	apolipoprotein A-I receptor binding(GO:0034191)
0.2	2.7	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.2	0.6	GO:0000403	Y-form DNA binding(GO:0000403)
0.2	2.6	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	1.6	GO:0001671	ATPase activator activity(GO:0001671)
0.2	0.6	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.2	1.4	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.2	1.9	GO:0017065	single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.2	0.4	GO:0001069	regulatory region RNA binding(GO:0001069)
0.2	0.8	GO:0043237	laminin-1 binding(GO:0043237)
0.2	0.6	GO:0032564	dATP binding(GO:0032564)
0.2	0.9	GO:0016623	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.2	0.6	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.2	3.4	GO:0031489	myosin V binding(GO:0031489)
0.2	0.4	GO:0098988	G-protein coupled glutamate receptor activity(GO:0098988)
0.2	0.7	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.2	0.7	GO:0004969	histamine receptor activity(GO:0004969)
0.2	1.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.2	0.7	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.2	0.5	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.2	1.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.2	0.7	GO:0005346	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.2	0.5	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.2	0.2	GO:0043733	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.2	4.4	GO:0070888	E-box binding(GO:0070888)
0.2	2.2	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.2	0.9	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2	1.2	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.2	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2	1.5	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.2	0.9	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.1	3.9	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.1	0.1	GO:0009041	uridylate kinase activity(GO:0009041)
0.1	0.4	GO:0035939	microsatellite binding(GO:0035939)
0.1	0.7	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.6	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.4	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.5	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.4	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1	3.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.1	0.5	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.5	GO:0034584	piRNA binding(GO:0034584)
0.1	0.4	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1	1.0	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.1	0.6	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.1	0.2	GO:0038191	neuropilin binding(GO:0038191)
0.1	0.7	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1	0.4	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.1	1.0	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1	0.4	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1	1.9	GO:0005112	Notch binding(GO:0005112)
0.1	1.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.1	0.3	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.1	0.3	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	0.3	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1	0.2	GO:0042895	antibiotic transporter activity(GO:0042895)
0.1	0.4	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.1	0.3	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	0.7	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.1	2.9	GO:0004364	glutathione transferase activity(GO:0004364)
0.1	0.7	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.1	3.7	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.1	0.3	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.1	0.2	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1	1.0	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.9	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.2	GO:0004127	cytidylate kinase activity(GO:0004127)
0.1	1.1	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.1	0.9	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	2.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1	1.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.1	0.3	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1	0.8	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1	1.1	GO:0015026	coreceptor activity(GO:0015026)
0.1	0.3	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.7	GO:0001972	retinoic acid binding(GO:0001972)
0.1	0.6	GO:0042301	phosphate ion binding(GO:0042301)
0.1	0.9	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	0.8	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.1	0.9	GO:0001054	RNA polymerase I activity(GO:0001054)
0.1	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.1	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1	0.3	GO:0005047	signal recognition particle binding(GO:0005047)
0.1	1.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	0.1	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.1	0.5	GO:0033691	sialic acid binding(GO:0033691)
0.1	0.4	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	0.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	1.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.1	0.5	GO:0039706	co-receptor binding(GO:0039706)
0.1	0.3	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.1	0.6	GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1	0.2	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1	0.2	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1	0.2	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1	0.2	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.1	0.1	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0	0.2	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.2	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.0	0.1	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.0	0.9	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	4.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.3	GO:0031386	protein tag(GO:0031386)
0.0	0.2	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.0	0.8	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.2	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.6	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.4	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.4	GO:0052736	dextrin alpha-glucosidase activity(GO:0044653) starch alpha-glucosidase activity(GO:0044654) beta-glucanase activity(GO:0052736) beta-6-sulfate-N-acetylglucosaminidase activity(GO:0052769) glucan endo-1,4-beta-glucosidase activity(GO:0052859)
0.0	0.2	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0043199	sulfate binding(GO:0043199)
0.0	0.0	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.1	GO:0036310	annealing helicase activity(GO:0036310)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.3	GO:0005186	pheromone activity(GO:0005186)
0.0	0.1	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.0	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0	0.1	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.0	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	2.6	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
1.3	40.0	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.8	15.0	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.6	1.8	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.5	2.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.5	1.0	PID S1P S1P3 PATHWAY	S1P3 pathway
0.4	5.7	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.4	0.7	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.4	3.9	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.3	6.9	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.3	6.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.3	7.7	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.3	4.6	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.2	8.4	PID FGF PATHWAY	FGF signaling pathway
0.2	1.6	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	0.5	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.2	5.4	ST ADRENERGIC	Adrenergic Pathway
0.2	3.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.2	6.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.2	0.5	PID IL3 PATHWAY	IL3-mediated signaling events
0.2	5.1	PID CDC42 PATHWAY	CDC42 signaling events
0.1	0.7	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	3.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	0.8	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	2.9	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	1.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	0.6	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.1	2.7	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	0.3	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	2.4	PID SHP2 PATHWAY	SHP2 signaling
0.1	1.4	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	1.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	0.7	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	0.6	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	1.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	3.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.0	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	2.9	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
1.4	1.4	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
1.2	9.5	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
1.1	11.9	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
1.1	27.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
1.0	14.7	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.9	6.5	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.9	0.9	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.8	16.5	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.8	7.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.8	19.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.7	11.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.6	10.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.6	7.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.6	9.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.6	11.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.5	10.1	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.4	8.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.4	7.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.4	16.2	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.4	2.6	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	3.9	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.3	2.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.3	3.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	5.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.3	0.9	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.3	1.3	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.3	12.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.3	4.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.3	7.0	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.3	1.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.3	2.7	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.3	1.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.3	2.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	2.0	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.2	4.5	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.2	2.7	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.2	1.9	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.2	1.3	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.2	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	1.2	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.2	2.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.2	2.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.2	2.3	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.2	5.3	REACTOME RNA POL III TRANSCRIPTION	Genes involved in RNA Polymerase III Transcription
0.2	1.3	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.2	2.0	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.2	0.8	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.2	1.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	6.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	2.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1	1.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	2.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.1	0.8	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	1.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	1.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	0.1	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.1	0.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	3.0	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	0.8	REACTOME OPSINS	Genes involved in Opsins
0.1	1.8	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	1.2	REACTOME POL SWITCHING	Genes involved in Polymerase switching
0.1	0.9	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	0.9	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	1.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	0.1	REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS	Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1	2.3	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.1	1.1	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.1	0.6	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	0.3	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1	1.0	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.1	0.2	REACTOME TRANSCRIPTION COUPLED NER TC NER	Genes involved in Transcription-coupled NER (TC-NER)
0.1	0.9	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.1	0.1	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	1.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.9	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1	0.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	0.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.1	0.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.4	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.9	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	1.2	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	1.3	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.4	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.1	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.5	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.2	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.7	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.5	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors

Results for Alx4

Z-value: 3.70

Motif logo

Transcription factors associated with Alx4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Alx4 motif across conditions

Conditions sorted by the z-value of the Alx4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Alx4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: