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ENCODE: ATAC-seq of different tissues during embryonic development
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Results for Arnt2

Z-value: 0.41

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Transcription factors associated with Arnt2

Gene Symbol Gene ID Gene Info
Arnt2
ENSMUSG00000015709.8 aryl hydrocarbon receptor nuclear translocator 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_84372464_84372615Arnt280.976165-0.402.8e-03Click!
chr7_84275389_84275540Arnt24070.8316380.341.1e-02Click!
chr7_84285970_84286121Arnt236510.209795-0.331.5e-02Click!
chr7_84403485_84403681Arnt263000.181922-0.302.4e-02Click!
chr7_84307654_84307850Arnt232260.213132-0.302.8e-02Click!

Activity of the Arnt2 motif across conditions

Conditions sorted by the z-value of the Arnt2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr16_15253127_15253318 1.36 Gm5404
 predicted gene 5404
 34378
 0.16
chr2_170130477_170131578 0.90 Zfp217
 zinc finger protein 217
 193
 0.97
chr12_69437182_69437482 0.81 5830428M24Rik
 RIKEN cDNA 5830428M24 gene
 30060
 0.12
chr1_85251281_85252082 0.77 C130026I21Rik
 RIKEN cDNA C130026I21 gene
 2867
 0.17
chr14_115040506_115042372 0.75 Mir17hg
 Mir17 host gene (non-protein coding)
 1440
 0.19
chr15_97042032_97042236 0.73 Slc38a4
 solute carrier family 38, member 4
 7953
 0.28
chr2_152636359_152637068 0.67 Rem1
 rad and gem related GTP binding protein 1
 3746
 0.1
chr19_23758061_23759360 0.65 Apba1
 amyloid beta (A4) precursor protein binding, family A, member 1
 177
 0.94
chr1_69106914_69108095 0.64 Erbb4
 erb-b2 receptor tyrosine kinase 4
 252
 0.82
chr1_85166981_85167344 0.57 Gm6264
 predicted gene 6264
 6299
 0.11
chr7_71960732_71961203 0.55 1700011C11Rik
 RIKEN cDNA 1700011C11 gene
 206
 0.9
chr11_36873121_36873272 0.55 Tenm2
 teneurin transmembrane protein 2
 70970
 0.14
chr11_96414118_96414269 0.54 Gm11531
 predicted gene 11531
 22081
 0.1
chr13_72419489_72419940 0.52 Rpl9-ps4
 ribosomal protein L9, pseudogene 4
 35626
 0.14
chr13_73263734_73263998 0.50 Irx4
 Iroquois homeobox 4
 3369
 0.2
chr7_44553417_44554082 0.49 Nr1h2
 nuclear receptor subfamily 1, group H, member 2
 41
 0.92
chr1_85092888_85093459 0.48 Gm10553
 predicted gene 10553
 6339
 0.1
chr14_19131787_19131938 0.47 Gm8582
 predicted gene 8582
 4062
 0.15
chr8_122511564_122511947 0.47 Gm26497
 predicted gene, 26497
 8919
 0.09
chr7_118491741_118492257 0.47 Itpripl2
 inositol 1,4,5-triphosphate receptor interacting protein-like 2
 24
 0.97
chr2_101752020_101752171 0.46 Prr5l
 proline rich 5 like
 45555
 0.14
chr11_85832197_85833021 0.45 Tbx2
 T-box 2
 58
 0.84
chr9_18473066_18474201 0.42 Zfp558
 zinc finger protein 558
 74
 0.95
chr19_43957421_43957601 0.42 Cpn1
 carboxypeptidase N, polypeptide 1
 11182
 0.13
chr19_5094164_5095202 0.42 Cnih2
 cornichon family AMPA receptor auxiliary protein 2
 3699
 0.08
chr19_38026271_38026463 0.41 Myof
 myoferlin
 16984
 0.15
chr8_121786646_121786834 0.41 Klhdc4
 kelch domain containing 4
 10688
 0.12
chr10_80948620_80948940 0.41 Gm3828
 predicted gene 3828
 5930
 0.1
chr17_25433917_25434633 0.40 Cacna1h
 calcium channel, voltage-dependent, T type, alpha 1H subunit
 492
 0.69
chr2_127415922_127416073 0.39 Gpat2
 glycerol-3-phosphate acyltransferase 2, mitochondrial
 9202
 0.15
chr1_191184878_191185214 0.38 Atf3
 activating transcription factor 3
 1706
 0.28
chr1_85617918_85618139 0.38 Gm10552
 predicted gene 10552
 6132
 0.1
chr7_63816080_63816231 0.38 Gm7482
 predicted gene 7482
 4825
 0.18
chr12_84408114_84409175 0.37 Entpd5
 ectonucleoside triphosphate diphosphohydrolase 5
 340
 0.53
chr12_86882228_86883612 0.37 Irf2bpl
 interferon regulatory factor 2 binding protein-like
 1878
 0.33
chr15_8279549_8279700 0.37 Cplane1
 ciliogenesis and planar polarity effector 1
 32521
 0.18
chr11_74896307_74898160 0.36 Sgsm2
 small G protein signaling modulator 2
 173
 0.84
chr2_26604241_26604792 0.35 Agpat2
 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
 99
 0.92
chr7_142561215_142561756 0.35 Nctc1
 non-coding transcript 1
 2889
 0.14
chr17_75014632_75015003 0.35 Ltbp1
 latent transforming growth factor beta binding protein 1
 8523
 0.24
chr16_38362984_38363227 0.35 Popdc2
 popeye domain containing 2
 860
 0.48
chr2_26503184_26504033 0.35 Notch1
 notch 1
 214
 0.89
chr2_138256185_138257474 0.34 Btbd3
 BTB (POZ) domain containing 3
 159
 0.98
chr3_96451263_96451652 0.34 BC107364
 cDNA sequence BC107364
 849
 0.24
chr2_74732641_74732796 0.34 Hoxd3
 homeobox D3
 195
 0.81
chr7_99351180_99351446 0.34 Serpinh1
 serine (or cysteine) peptidase inhibitor, clade H, member 1
 1684
 0.3
chr10_86300212_86300618 0.34 Timp3
 tissue inhibitor of metalloproteinase 3
 43
 0.98
chr3_8717321_8717847 0.34 C230057A21Rik
 RIKEN cDNA C230057A21 gene
 18616
 0.14
chr14_27114666_27114961 0.34 Arhgef3
 Rho guanine nucleotide exchange factor (GEF) 3
 86
 0.98
chr11_81612309_81613487 0.33 Gm11418
 predicted gene 11418
 25537
 0.22
chr9_32901255_32901639 0.33 Gm27162
 predicted gene 27162
 27519
 0.18
chr1_39721483_39721634 0.33 Rfx8
 regulatory factor X 8
 561
 0.78
chr10_103001022_103001290 0.33 Alx1
 ALX homeobox 1
 21418
 0.19
chr5_128598799_128598977 0.33 Gm42498
 predicted gene 42498
 932
 0.43
chr7_100911356_100911541 0.32 Arhgef17
 Rho guanine nucleotide exchange factor (GEF) 17
 16758
 0.13
chr15_66961775_66961932 0.32 Ndrg1
 N-myc downstream regulated gene 1
 6072
 0.18
chr10_121475538_121476618 0.32 Rassf3
 Ras association (RalGDS/AF-6) domain family member 3
 269
 0.86
chr5_125264626_125264993 0.32 Gm32585
 predicted gene, 32585
 8006
 0.18
chr5_107195880_107196420 0.32 Tgfbr3
 transforming growth factor, beta receptor III
 3783
 0.2
chr7_110982411_110982739 0.32 Mrvi1
 MRV integration site 1
 114
 0.97
chr8_11476357_11476528 0.31 E230013L22Rik
 RIKEN cDNA E230013L22 gene
 1487
 0.25
chr2_72614373_72614524 0.31 Pex13-ps
 peroxisomal biogenesis factor 13, pseudogene
 17822
 0.16
chr1_88213749_88214214 0.31 Ugt1a1
 UDP glucuronosyltransferase 1 family, polypeptide A1
 2022
 0.13
chr14_27823142_27823309 0.31 Erc2
 ELKS/RAB6-interacting/CAST family member 2
 24667
 0.22
chr8_15027100_15028701 0.31 Gm37844
 predicted gene, 37844
 522
 0.44
chr9_50752051_50752676 0.30 Hspb2
 heat shock protein 2
 9
 0.88
chr5_43232754_43234178 0.30 Cpeb2
 cytoplasmic polyadenylation element binding protein 2
 296
 0.85
chr1_132346162_132346444 0.30 F730311O21Rik
 RIKEN cDNA F730311O21 gene
 4280
 0.14
chr13_35740610_35741587 0.30 Cdyl
 chromodomain protein, Y chromosome-like
 215
 0.94
chr4_135876235_135877013 0.30 Pnrc2
 proline-rich nuclear receptor coactivator 2
 2774
 0.15
chr13_41605449_41606727 0.29 Tmem170b
 transmembrane protein 170B
 128
 0.96
chr17_26414662_26415402 0.29 Neurl1b
 neuralized E3 ubiquitin protein ligase 1B
 67
 0.97
chr4_149954471_149955779 0.29 Spsb1
 splA/ryanodine receptor domain and SOCS box containing 1
 82
 0.97
chr6_63257322_63257806 0.29 9330118I20Rik
 RIKEN cDNA 9330118I20 gene
 61
 0.93
chr8_69995796_69997172 0.27 Gatad2a
 GATA zinc finger domain containing 2A
 100
 0.95
chr7_45588766_45589660 0.27 Bcat2
 branched chain aminotransferase 2, mitochondrial
 3792
 0.07
chr5_140606846_140607467 0.27 Lfng
 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
 164
 0.83
chr15_81585272_81586453 0.27 Gm23880
 predicted gene, 23880
 271
 0.52
chr5_53998183_53999428 0.27 Stim2
 stromal interaction molecule 2
 240
 0.95
chr1_89538633_89538887 0.27 Gm25180
 predicted gene, 25180
 24600
 0.16
chr5_147758193_147758351 0.27 Gm43156
 predicted gene 43156
 12756
 0.19
chr1_72945188_72945345 0.27 1700027A15Rik
 RIKEN cDNA 1700027A15 gene
 39578
 0.16
chr2_26595840_26596165 0.27 Egfl7
 EGF-like domain 7
 3855
 0.1
chr13_56588245_56589118 0.26 2010203P06Rik
 RIKEN cDNA 2010203P06 gene
 6856
 0.18
chr14_57057660_57057892 0.26 Gja3
 gap junction protein, alpha 3
 53
 0.97
chr9_56994536_56995264 0.26 Ptpn9
 protein tyrosine phosphatase, non-receptor type 9
 23
 0.97
chr14_34560304_34560455 0.26 Ldb3
 LIM domain binding 3
 16615
 0.11
chr16_29977900_29978051 0.26 Gm1968
 predicted gene 1968
 1209
 0.44
chr2_32884809_32884960 0.26 Fam129b
 family with sequence similarity 129, member B
 8770
 0.11
chr11_62789333_62789872 0.26 Zfp286
 zinc finger protein 286
 140
 0.92
chr10_127516477_127517046 0.25 Ndufa4l2
 Ndufa4, mitochondrial complex associated like 2
 1794
 0.18
chr9_108480057_108480354 0.25 Lamb2
 laminin, beta 2
 324
 0.71
chr19_10304418_10305190 0.25 Dagla
 diacylglycerol lipase, alpha
 53
 0.97
chr8_69654078_69655164 0.25 Zfp964
 zinc finger protein 964
 129
 0.95
chr1_189615380_189615531 0.25 Gm38122
 predicted gene, 38122
 24779
 0.18
chr3_105018285_105018436 0.25 Gm40117
 predicted gene, 40117
 24328
 0.13
chr15_76206813_76207932 0.25 Plec
 plectin
 881
 0.36
chr8_122546722_122547355 0.24 Piezo1
 piezo-type mechanosensitive ion channel component 1
 4291
 0.11
chr16_92345192_92345711 0.24 Kcne1
 potassium voltage-gated channel, Isk-related subfamily, member 1
 13423
 0.11
chr8_71381974_71382671 0.24 Nr2f6
 nuclear receptor subfamily 2, group F, member 6
 362
 0.74
chr7_136406485_136406636 0.24 Gm36849
 predicted gene, 36849
 53196
 0.14
chr4_117985332_117985486 0.23 9530034E10Rik
 RIKEN cDNA 9530034E10 gene
 10373
 0.15
chr5_134742453_134742604 0.23 Gm30003
 predicted gene, 30003
 4514
 0.16
chr11_70608772_70609053 0.23 Mink1
 misshapen-like kinase 1 (zebrafish)
 826
 0.32
chr11_59364469_59364771 0.23 Gm15755
 predicted gene 15755
 10841
 0.12
chr8_24438713_24439074 0.23 Tcim
 transcriptional and immune response regulator
 91
 0.96
chr15_6386264_6386948 0.23 Dab2
 disabled 2, mitogen-responsive phosphoprotein
 8
 0.98
chr17_56672739_56673924 0.23 Ranbp3
 RAN binding protein 3
 27
 0.96
chr7_49527689_49528213 0.22 Nav2
 neuron navigator 2
 20241
 0.23
chr1_60652807_60652958 0.22 Gm23762
 predicted gene, 23762
 39079
 0.1
chr15_83724974_83725683 0.22 Scube1
 signal peptide, CUB domain, EGF-like 1
 307
 0.92
chr17_66448520_66450314 0.22 Mtcl1
 microtubule crosslinking factor 1
 333
 0.57
chr11_30648868_30649937 0.22 Acyp2
 acylphosphatase 2, muscle type
 185
 0.95
chr1_93754379_93755416 0.22 Atg4b
 autophagy related 4B, cysteine peptidase
 8
 0.5
chr6_65670118_65670269 0.22 Ndnf
 neuron-derived neurotrophic factor
 1397
 0.49
chr9_44734596_44735576 0.22 Phldb1
 pleckstrin homology like domain, family B, member 1
 112
 0.91
chr14_47921837_47922130 0.21 4930447J18Rik
 RIKEN cDNA 4930447J18 gene
 23074
 0.15
chr9_60837244_60837770 0.21 Gm9869
 predicted gene 9869
 692
 0.7
chr7_143777485_143777636 0.21 Gm44998
 predicted gene 44998
 2447
 0.15
chr9_35331987_35332138 0.21 Gm33838
 predicted gene, 33838
 24463
 0.11
chr13_43864441_43864954 0.21 Gm33195
 predicted gene, 33195
 28
 0.97
chr4_129928556_129928707 0.21 Spocd1
 SPOC domain containing 1
 618
 0.62
chr10_25359547_25360523 0.21 Epb41l2
 erythrocyte membrane protein band 4.1 like 2
 179
 0.95
chr6_141249885_141250621 0.20 Gm28523
 predicted gene 28523
 244
 0.55
chr11_53904266_53904446 0.20 Gm12218
 predicted gene 12218
 1201
 0.29
chr2_145787427_145787839 0.20 Rin2
 Ras and Rab interactor 2
 1471
 0.48
chr9_41889978_41890642 0.20 Gm40513
 predicted gene, 40513
 294
 0.89
chr2_27212365_27212516 0.20 Sardh
 sarcosine dehydrogenase
 2503
 0.21
chr12_32378513_32379490 0.20 Ccdc71l
 coiled-coil domain containing 71 like
 297
 0.93
chr3_146117348_146117511 0.20 Mcoln3
 mucolipin 3
 21
 0.96
chr3_99183530_99183681 0.20 Gm18982
 predicted gene, 18982
 2324
 0.2
chr2_26491019_26491170 0.19 Notch1
 notch 1
 12728
 0.1
chr8_94377668_94378018 0.19 Gm15889
 predicted gene 15889
 29
 0.95
chr7_99626901_99627081 0.19 Tpbgl
 trophoblast glycoprotein-like
 112
 0.9
chr10_13473756_13474638 0.19 Phactr2
 phosphatase and actin regulator 2
 215
 0.94
chr5_112166735_112167033 0.19 1700016B01Rik
 RIKEN cDNA 1700016B01 gene
 10647
 0.17
chr1_88701358_88702305 0.19 Arl4c
 ADP-ribosylation factor-like 4C
 45
 0.97
chr9_70243232_70243383 0.19 Myo1e
 myosin IE
 35939
 0.17
chr4_149999267_149999418 0.19 H6pd
 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
 1923
 0.28
chr11_107547352_107548463 0.19 Helz
 helicase with zinc finger domain
 23
 0.88
chr19_5567497_5568487 0.19 Ap5b1
 adaptor-related protein complex 5, beta 1 subunit
 33
 0.93
chr13_31798221_31798372 0.18 Gm11379
 predicted gene 11379
 757
 0.63
chr7_31115171_31115481 0.18 Hpn
 hepsin
 36
 0.95
chr8_120804879_120805047 0.18 Irf8
 interferon regulatory factor 8
 52754
 0.1
chr4_142077883_142078172 0.18 Tmem51os1
 Tmem51 opposite strand 1
 5945
 0.15
chr4_120144444_120144645 0.18 Edn2
 endothelin 2
 16662
 0.22
chr11_103244905_103245215 0.17 Map3k14
 mitogen-activated protein kinase kinase kinase 14
 2789
 0.17
chr7_66427385_66427727 0.17 Aldh1a3
 aldehyde dehydrogenase family 1, subfamily A3
 39
 0.97
chrY_90771840_90772811 0.17 Gm47283
 predicted gene, 47283
 12413
 0.17
chr17_31686321_31686544 0.17 Gm50222
 predicted gene, 50222
 2058
 0.19
chr5_99375821_99375972 0.17 Gm35394
 predicted gene, 35394
 101801
 0.07
chr5_106801577_106801728 0.17 Gm8365
 predicted gene 8365
 62888
 0.09
chr8_13695607_13695765 0.17 Cfap97d2
 CFAP97 domain containing 2
 10203
 0.16
chr17_71782235_71783145 0.17 Clip4
 CAP-GLY domain containing linker protein family, member 4
 73
 0.97
chr10_79866106_79866295 0.17 Plppr3
 phospholipid phosphatase related 3
 1081
 0.19
chr5_33695613_33695860 0.17 Gm42965
 predicted gene 42965
 12762
 0.1
chr11_75462938_75463374 0.17 Mir22
 microRNA 22
 560
 0.47
chr5_111532860_111533036 0.17 C130026L21Rik
 RIKEN cDNA C130026L21 gene
 48474
 0.13
chr19_5414445_5414596 0.17 Gm6293
 predicted pseudogene 6293
 1239
 0.16
chr13_106936192_106937354 0.17 Ipo11
 importin 11
 172
 0.93
chr15_76465093_76465561 0.17 Scx
 scleraxis
 7807
 0.08
chr10_42614130_42614512 0.16 Ostm1
 osteopetrosis associated transmembrane protein 1
 30483
 0.16
chr1_182090368_182090591 0.16 Gm37177
 predicted gene, 37177
 19076
 0.14
chr1_184731813_184732486 0.16 Hlx
 H2.0-like homeobox
 470
 0.75
chr4_133680182_133680333 0.16 Pigv
 phosphatidylinositol glycan anchor biosynthesis, class V
 7610
 0.13
chr1_33488501_33488652 0.16 Gm29228
 predicted gene 29228
 6475
 0.23
chr2_152734500_152735322 0.16 Id1
 inhibitor of DNA binding 1, HLH protein
 1340
 0.29
chr6_72235086_72235414 0.16 Atoh8
 atonal bHLH transcription factor 8
 20
 0.97
chr1_31017458_31017792 0.16 4931428L18Rik
 RIKEN cDNA 4931428L18 gene
 17721
 0.14
chr11_86993066_86994378 0.16 Ypel2
 yippee like 2
 15
 0.97
chr7_6382694_6383817 0.16 Zfp28
 zinc finger protein 28
 40
 0.94
chr3_100462225_100462649 0.16 Gm43121
 predicted gene 43121
 24603
 0.11
chr11_97415706_97416357 0.15 Arhgap23
 Rho GTPase activating protein 23
 498
 0.76
chr10_62792164_62792669 0.15 Ccar1
 cell division cycle and apoptosis regulator 1
 130
 0.93
chr15_102105460_102106270 0.15 Tns2
 tensin 2
 753
 0.51
chr11_119807843_119807994 0.15 Rptor
 regulatory associated protein of MTOR, complex 1
 3328
 0.23
chr19_43440308_43441144 0.15 Gm47936
 predicted gene, 47936
 266
 0.5
chr6_97311994_97312190 0.15 Frmd4b
 FERM domain containing 4B
 288
 0.93
chr18_61056422_61056649 0.15 Pdgfrb
 platelet derived growth factor receptor, beta polypeptide
 11335
 0.13
chr2_148044552_148044703 0.15 Foxa2
 forkhead box A2
 837
 0.56
chr9_107908926_107909153 0.15 Mst1r
 macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
 2132
 0.13
chr8_102786860_102787011 0.15 Cdh11
 cadherin 11
 1293
 0.45
chr2_91656850_91657112 0.15 Arhgap1
 Rho GTPase activating protein 1
 3773
 0.13
chr7_28277569_28278227 0.14 Eid2b
 EP300 interacting inhibitor of differentiation 2B
 159
 0.89
chr17_10093886_10094100 0.14 Qk
 quaking
 119581
 0.06
chr10_80656363_80657283 0.14 Btbd2
 BTB (POZ) domain containing 2
 248
 0.82
chr2_75997808_75997959 0.14 Pde11a
 phosphodiesterase 11A
 8160
 0.17
chr7_130865550_130866588 0.14 Plekha1
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
 159
 0.63
chr12_86974721_86975193 0.14 Zdhhc22
 zinc finger, DHHC-type containing 22
 8878
 0.15
chr18_76035512_76035730 0.14 1700003O11Rik
 RIKEN cDNA 1700003O11 gene
 19944
 0.19
chr11_106036361_106037705 0.14 Dcaf7
 DDB1 and CUL4 associated factor 7
 133
 0.92
chr7_133047426_133047577 0.14 Ctbp2
 C-terminal binding protein 2
 17385
 0.17
chr11_33871976_33872356 0.14 Kcnip1
 Kv channel-interacting protein 1
 28581
 0.21
chr9_48835918_48836556 0.13 Zbtb16
 zinc finger and BTB domain containing 16
 15
 0.98
chr15_103366694_103366859 0.13 Itga5
 integrin alpha 5 (fibronectin receptor alpha)
 13
 0.96
chr15_103169326_103169551 0.13 Smug1
 single-strand selective monofunctional uracil DNA glycosylase
 2346
 0.18
chr15_86202694_86203051 0.13 Gm22818
 predicted gene, 22818
 9785
 0.16
chr2_153256681_153256832 0.13 Pofut1
 protein O-fucosyltransferase 1
 726
 0.59
chr7_97737443_97738488 0.13 Aqp11
 aquaporin 11
 27
 0.97
chr17_47842318_47842529 0.13 Gm25201
 predicted gene, 25201
 1438
 0.29

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Arnt2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.4 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.5 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.1 0.3 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.4 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.2 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 0.2 GO:0038171 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.1 0.2 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.1 0.5 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.1 0.2 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.2 GO:2000611 positive regulation of thyroid hormone generation(GO:2000611)
0.1 0.2 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.1 0.4 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.3 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.3 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.5 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0034651 cortisol biosynthetic process(GO:0034651)
0.0 0.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.6 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.0 GO:0032532 regulation of microvillus length(GO:0032532)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0051138 regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.0 GO:0046061 dATP catabolic process(GO:0046061)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.2 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.0 GO:0043096 purine nucleobase salvage(GO:0043096)
0.0 0.2 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.0 GO:0035993 deltoid tuberosity development(GO:0035993)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0060406 positive regulation of penile erection(GO:0060406)
0.0 0.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 0.0 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.0 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.1 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.0 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.0 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.0 0.0 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.0 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.2 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.0 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.9 GO:0005901 caveola(GO:0005901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.6 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.0 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0001031 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.0 1.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.4 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors