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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Atf5

Z-value: 0.92

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Transcription factors associated with Atf5

Gene Symbol	Gene ID	Gene Info
Atf5 Ensembl NCBI MGI UniProt	ENSMUSG00000038539.8	activating transcription factor 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_44810882_44811033	Atf5	4701	0.081870	-0.07	6.0e-01	Click!
chr7_44811834_44811985	Atf5	3749	0.088043	0.05	7.2e-01	Click!
chr7_44815501_44816067	Atf5	126	0.648079	-0.04	7.8e-01	Click!
chr7_44816492_44816747	Atf5	39	0.585553	-0.03	8.4e-01	Click!
chr7_44816830_44816990	Atf5	252	0.547035	0.00	9.8e-01	Click!

Activity of the Atf5 motif across conditions

Conditions sorted by the z-value of the Atf5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_171719022_171719184	3.84	1700028P15Rik	RIKEN cDNA 1700028P15 gene	243028	0.02
chr15_96657412_96657566	1.64	Gm22045	predicted gene, 22045	14304	0.17
chr18_65071299_65071456	1.56	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	4655	0.27
chr9_95794485_95794682	1.48	Pls1	plastin 1 (I-isoform)	20823	0.15
chr3_52510877_52511032	1.40	Gm30173	predicted gene, 30173	6010	0.26
chr4_134062182_134062374	1.40	Crybg2	crystallin beta-gamma domain containing 2	1463	0.26
chr16_93366305_93366471	1.38	1810053B23Rik	RIKEN cDNA 1810053B23 gene	280	0.87
chr14_62156960_62157143	1.36	Gm35419	predicted gene, 35419	14075	0.22
chr18_61457963_61458137	1.33	Gm25834	predicted gene, 25834	9103	0.12
chr14_99280961_99281121	1.31	Gm4412	predicted gene 4412	10595	0.18
chr3_101709597_101709951	1.24	Gm43135	predicted gene 43135	17985	0.19
chrX_100796807_100796994	1.23	Dlg3	discs large MAGUK scaffold protein 3	323	0.89
chr10_62419520_62419689	1.23	Hkdc1	hexokinase domain containing 1	2804	0.2
chr3_82946486_82946637	1.23	Rbm46os	RNA binding motif protein 46, opposite strand	42084	0.11
chr2_13484748_13484899	1.22	Cubn	cubilin (intrinsic factor-cobalamin receptor)	6990	0.26
chr5_146682984_146683282	1.22	4930573C15Rik	RIKEN cDNA 4930573C15 gene	23489	0.15
chr10_99918623_99918821	1.16	Gm47579	predicted gene, 47579	52702	0.12
chr19_55865164_55865315	1.14	Ppnr	per-pentamer repeat gene	23567	0.21
chr4_3699376_3699541	1.13	Lyn	LYN proto-oncogene, Src family tyrosine kinase	21328	0.14
chr2_49811690_49811841	1.11	Gm13480	predicted gene 13480	1183	0.54
chr2_76418227_76418378	1.11	Osbpl6	oxysterol binding protein-like 6	11741	0.19
chr15_8469447_8469598	1.07	Gm49247	predicted gene, 49247	12423	0.14
chr8_68432735_68432886	1.07	Gm15656	predicted gene 15656	24338	0.2
chr6_16898406_16898748	1.03	Tfec	transcription factor EC	136	0.97
chr13_56153187_56153343	1.02	Gm25148	predicted gene, 25148	14335	0.14
chr7_135508978_135509129	1.01	Clrn3	clarin 3	19601	0.15
chr19_28382711_28382862	1.00	Glis3	GLIS family zinc finger 3	56780	0.15
chr7_83827500_83827791	0.98	Gm44993	predicted gene 44993	6954	0.12
chr11_75560591_75560742	0.97	Slc43a2	solute carrier family 43, member 2	155	0.91
chr11_89298005_89298267	0.94	Nog	noggin	4196	0.24
chr18_43724780_43724931	0.93	Spink1	serine peptidase inhibitor, Kazal type 1	12702	0.18
chr19_11794415_11794566	0.92	Stx3	syntaxin 3	4873	0.12
chr4_145009448_145009619	0.91	Vps13d	vacuolar protein sorting 13D	25572	0.19
chr5_107987777_107987957	0.91	Dipk1a	divergent protein kinase domain 1A	782	0.56
chr5_111943856_111944042	0.90	Gm42488	predicted gene 42488	286	0.94
chr1_36275743_36275895	0.90	Neurl3	neuralized E3 ubiquitin protein ligase 3	1140	0.43
chr6_49148881_49149069	0.90	Gm18010	predicted gene, 18010	23784	0.12
chr1_132150735_132150929	0.90	Cdk18	cyclin-dependent kinase 18	11148	0.11
chr4_72865530_72865691	0.90	Aldoart1	aldolase 1 A, retrogene 1	12976	0.21
chr2_122658059_122658461	0.89	Mir147	microRNA 147	17457	0.12
chr4_91375919_91376105	0.89	Elavl2	ELAV like RNA binding protein 1	295	0.9
chr6_37748257_37748408	0.89	Atp6v0c-ps2	ATPase, H+ transporting, lysosomal V0 subunit C, pseudogene 2	57754	0.12
chr1_126673237_126673584	0.87	Nckap5	NCK-associated protein 5	64780	0.15
chr2_145620836_145620998	0.86	Slc24a3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	14099	0.21
chr11_25057681_25057866	0.86	Gm12665	predicted gene 12665	131715	0.05
chr14_74910472_74910649	0.85	Lrch1	leucine-rich repeats and calponin homology (CH) domain containing 1	10838	0.2
chr17_31329029_31329180	0.85	Slc37a1	solute carrier family 37 (glycerol-3-phosphate transporter), member 1	3477	0.18
chr1_77458956_77459117	0.85	Mir6352	microRNA 6352	37732	0.17
chr10_120652419_120652570	0.84	Gm38289	predicted gene, 38289	14523	0.16
chr16_24102970_24103178	0.84	Gm31583	predicted gene, 31583	12985	0.17
chr3_62885214_62885411	0.84	Gm9701	predicted gene 9701	38921	0.21
chr5_85239463_85240008	0.83	Gm21006	predicted gene, 21006	372890	0.01
chr1_61651640_61651803	0.83	Gm37205	predicted gene, 37205	2702	0.21
chr14_121147867_121148018	0.83	Farp1	FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)	45863	0.17
chr5_119071522_119071673	0.83	1700081H04Rik	RIKEN cDNA 1700081H04 gene	36637	0.18
chr5_67842366_67842749	0.82	Gm42466	predicted gene 42466	1863	0.22
chr18_7692774_7692925	0.82	Gm18763	predicted gene, 18763	123	0.97
chr3_107911678_107912011	0.80	Gm9515	predicted gene 9515	595	0.49
chr1_40657382_40657533	0.80	Slc9a2	solute carrier family 9 (sodium/hydrogen exchanger), member 2	23117	0.15
chr1_127352188_127352385	0.79	Gm23370	predicted gene, 23370	20473	0.15
chr5_39643023_39643174	0.78	Hs3st1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1	1499	0.44
chr2_93154685_93154867	0.77	Trp53i11	transformation related protein 53 inducible protein 11	32772	0.17
chr8_115929769_115930140	0.77	Gm45733	predicted gene 45733	42117	0.21
chr10_127878465_127878711	0.77	Rdh7	retinol dehydrogenase 7	9742	0.09
chr16_38945816_38946009	0.77	Gm22500	predicted gene, 22500	18703	0.2
chr18_21106064_21106215	0.77	Gm6378	predicted pseudogene 6378	29030	0.18
chr17_12231266_12231417	0.75	Map3k4	mitogen-activated protein kinase kinase kinase 4	1125	0.45
chr9_42108630_42108943	0.75	Sorl1	sortilin-related receptor, LDLR class A repeats-containing	15511	0.19
chr2_167345578_167345741	0.75	B4galt5	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5	3524	0.24
chr5_64345857_64346050	0.73	Gm43838	predicted gene 43838	14561	0.14
chr9_50924434_50924623	0.73	Gm25558	predicted gene, 25558	36578	0.13
chr3_98414665_98414838	0.73	Zfp697	zinc finger protein 697	32203	0.11
chr13_116309603_116310279	0.72	Isl1	ISL1 transcription factor, LIM/homeodomain	252	0.94
chr17_47276025_47276204	0.72	Gm26216	predicted gene, 26216	14842	0.17
chr9_78204280_78204549	0.72	Gm3126	predicted gene 3126	10431	0.1
chr13_84346636_84346793	0.72	Gm26927	predicted gene, 26927	6601	0.24
chr2_146057085_146057422	0.71	Cfap61	cilia and flagella associated protein 61	10002	0.26
chr1_180783015_180783214	0.70	Gm38293	predicted gene, 38293	14458	0.1
chr6_21787269_21787608	0.70	Tspan12	tetraspanin 12	64390	0.11
chr7_132580270_132580421	0.70	Oat	ornithine aminotransferase	3947	0.18
chr8_40641828_40641979	0.69	Mtmr7	myotubularin related protein 7	7106	0.17
chr1_182914638_182914812	0.69	Gm37542	predicted gene, 37542	7015	0.22
chr6_136173009_136173858	0.69	Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	56	0.85
chr14_20182148_20182394	0.69	Kcnk5	potassium channel, subfamily K, member 5	462	0.74
chr18_30958796_30959180	0.69	Rit2	Ras-like without CAAX 2	253744	0.02
chr9_96786211_96786362	0.68	C430002N11Rik	RIKEN cDNA C430002N11 gene	20685	0.13
chr2_168147840_168148000	0.68	Gm14235	predicted gene 14235	5613	0.13
chr11_117998450_117998628	0.67	Pgs1	phosphatidylglycerophosphate synthase 1	2256	0.23
chr3_82950733_82950884	0.67	Gm30097	predicted gene, 30097	44777	0.1
chr1_4538420_4538580	0.67	Gm38076	predicted gene, 38076	3214	0.17
chr8_35946808_35946959	0.66	Gm22030	predicted gene, 22030	30695	0.16
chrX_71962407_71962627	0.66	Prrg3	proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)	107	0.96
chr8_77787744_77787939	0.66	Gm23981	predicted gene, 23981	19694	0.18
chr7_35116712_35116864	0.66	Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	2505	0.14
chr1_37510099_37510250	0.66	Mgat4a	mannoside acetylglucosaminyltransferase 4, isoenzyme A	11336	0.15
chr7_128057106_128057257	0.66	Gm22809	predicted gene, 22809	4679	0.09
chr14_121471597_121471816	0.65	Gm33299	predicted gene, 33299	15944	0.16
chr4_155611887_155612038	0.65	Slc35e2	solute carrier family 35, member E2	1759	0.18
chr5_119588498_119588649	0.65	Gm43399	predicted gene 43399	9631	0.16
chr6_142759958_142760162	0.65	Cmas	cytidine monophospho-N-acetylneuraminic acid synthetase	3285	0.25
chr10_17680823_17680987	0.65	Gm47771	predicted gene, 47771	22392	0.19
chr1_158489494_158490042	0.64	Mir488	microRNA 488	15857	0.17
chr16_85144813_85144976	0.64	Gm49226	predicted gene, 49226	3935	0.22
chr9_36821758_36821952	0.64	Fez1	fasciculation and elongation protein zeta 1 (zygin I)	9	0.97
chr1_6188454_6188716	0.64	Rb1cc1	RB1-inducible coiled-coil 1	17612	0.21
chr11_18749533_18749697	0.63	Gm28401	predicted gene 28401	7123	0.18
chr17_78273911_78274066	0.62	Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	6195	0.2
chr18_61736928_61737079	0.62	1500015A07Rik	RIKEN cDNA 1500015A07 gene	2646	0.19
chr4_9124626_9124900	0.62	Gm23423	predicted gene, 23423	85240	0.1
chr10_75130767_75130964	0.62	Bcr	BCR activator of RhoGEF and GTPase	29495	0.17
chr7_101066013_101066314	0.62	Gm5735	predicted gene 5735	4688	0.18
chr16_18628137_18628905	0.62	Septin5	septin 5	1183	0.32
chr7_45112613_45112937	0.62	Fcgrt	Fc receptor, IgG, alpha chain transporter	8924	0.04
chr12_99239820_99240014	0.61	Gm19898	predicted gene, 19898	5754	0.2
chr3_125270894_125271310	0.61	Gm42826	predicted gene 42826	51549	0.18
chr6_22049315_22049466	0.61	Cped1	cadherin-like and PC-esterase domain containing 1	23447	0.24
chr9_64644172_64644464	0.61	Megf11	multiple EGF-like-domains 11	16141	0.22
chr10_80397435_80397912	0.61	Mbd3	methyl-CpG binding domain protein 3	1749	0.15
chr10_42941225_42941376	0.60	Scml4	Scm polycomb group protein like 4	1419	0.42
chr2_15188409_15188561	0.60	Gm13313	predicted gene 13313	60885	0.12
chr2_168677682_168678254	0.60	Atp9a	ATPase, class II, type 9A	7622	0.21
chr5_88888203_88888428	0.60	Slc4a4	solute carrier family 4 (anion exchanger), member 4	1016	0.59
chr10_111576755_111576942	0.59	4933440J02Rik	RIKEN cDNA 4933440J02 gene	17425	0.14
chr6_82112549_82112709	0.59	Gm15864	predicted gene 15864	60048	0.1
chr14_79202812_79202996	0.59	Gm4632	predicted gene 4632	3714	0.19
chr2_45747303_45747466	0.59	Gm13467	predicted gene 13467	4300	0.23
chr8_13897932_13898163	0.58	Gm7676	predicted gene 7676	1736	0.22
chr5_28368084_28368235	0.58	Rbm33	RNA binding motif protein 33	25896	0.21
chr3_95186356_95186507	0.57	Gabpb2	GA repeat binding protein, beta 2	5467	0.08
chr4_115090977_115091146	0.57	Pdzk1ip1	PDZK1 interacting protein 1	129	0.95
chr14_24244232_24244509	0.57	Dlg5	discs large MAGUK scaffold protein 5	495	0.6
chr2_101885551_101885778	0.57	Commd9	COMM domain containing 9	583	0.72
chrX_155175677_155175880	0.57	Gm8595	predicted gene 8595	3503	0.14
chr6_138143238_138143436	0.57	Mgst1	microsomal glutathione S-transferase 1	483	0.88
chrX_49288700_49288851	0.57	Enox2	ecto-NOX disulfide-thiol exchanger 2	516	0.84
chr12_108004995_108005731	0.57	Bcl11b	B cell leukemia/lymphoma 11B	1761	0.48
chr2_173256495_173256682	0.56	Pmepa1	prostate transmembrane protein, androgen induced 1	19601	0.16
chr9_23204316_23204709	0.56	Bmper	BMP-binding endothelial regulator	18564	0.29
chr10_41603865_41604016	0.56	Ccdc162	coiled-coil domain containing 162	7379	0.16
chr1_86501052_86501969	0.56	Ptma	prothymosin alpha	25216	0.11
chr6_105389344_105389512	0.56	Gm25570	predicted gene, 25570	10291	0.29
chr19_23133221_23133380	0.56	2410080I02Rik	RIKEN cDNA 2410080I02 gene	1600	0.34
chr1_165281433_165281813	0.55	Gpr161	G protein-coupled receptor 161	14166	0.15
chr5_134989871_134990055	0.55	Cldn3	claudin 3	3749	0.09
chr3_79841487_79841829	0.55	Tmem144	transmembrane protein 144	71	0.97
chr19_48766635_48766790	0.55	Gm50436	predicted gene, 50436	44424	0.18
chr6_38110952_38111103	0.54	Atp6v0a4	ATPase, H+ transporting, lysosomal V0 subunit A4	1478	0.3
chr4_115095464_115096252	0.54	Pdzk1ip1	PDZK1 interacting protein 1	4926	0.16
chr10_115774542_115774739	0.54	Tspan8	tetraspanin 8	42192	0.18
chr14_40927000_40927320	0.54	Tspan14	tetraspanin 14	7156	0.21
chr17_87628266_87628422	0.54	Epcam	epithelial cell adhesion molecule	7635	0.2
chr11_16299934_16300272	0.54	Vstm2a	V-set and transmembrane domain containing 2A	36885	0.19
chr13_104029581_104029750	0.54	Nln	neurolysin (metallopeptidase M3 family)	4908	0.23
chr10_75781389_75781553	0.53	Gstt3	glutathione S-transferase, theta 3	57	0.87
chr15_54571990_54572708	0.53	Mal2	mal, T cell differentiation protein 2	1157	0.59
chr8_104841536_104841695	0.53	Matr3-ps2	matrin 3, pseudogene 2	4758	0.11
chr16_39984230_39984435	0.53	Lsamp	limbic system-associated membrane protein	29	0.99
chr7_91262206_91262389	0.53	Gm24552	predicted gene, 24552	19302	0.18
chr11_74523672_74523823	0.52	Rap1gap2	RAP1 GTPase activating protein 2	996	0.59
chr11_108364191_108364347	0.52	Gm11656	predicted gene 11656	13608	0.16
chr3_3618701_3618867	0.52	Hnf4g	hepatocyte nuclear factor 4, gamma	15366	0.24
chr11_45835805_45836001	0.52	Gm22751	predicted gene, 22751	6124	0.14
chr5_147307043_147307597	0.52	Cdx2	caudal type homeobox 2	50	0.95
chr13_8113062_8113213	0.52	Gm5191	predicted gene 5191	14996	0.22
chr12_117053564_117054465	0.51	Gm10421	predicted gene 10421	97201	0.08
chr11_117686075_117686252	0.51	Tnrc6c	trinucleotide repeat containing 6C	31350	0.13
chr12_25125813_25125964	0.51	Gm17746	predicted gene, 17746	3286	0.21
chr8_74921062_74921461	0.51	Isx	intestine specific homeobox	47721	0.13
chr16_92610814_92610965	0.51	Gm26626	predicted gene, 26626	1925	0.38
chr6_94710006_94710162	0.51	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	9926	0.23
chr2_135029393_135029569	0.51	4930545L23Rik	RIKEN cDNA 4930545L23 gene	186135	0.03
chr8_74921531_74921848	0.51	Isx	intestine specific homeobox	48149	0.13
chr12_17742999_17743158	0.50	Hpcal1	hippocalcin-like 1	14852	0.22
chr2_22873263_22873419	0.50	Pdss1	prenyl (solanesyl) diphosphate synthase, subunit 1	22181	0.13
chr2_110191387_110191538	0.50	Gm13936	predicted gene 13936	5427	0.21
chr2_152080641_152081210	0.50	Scrt2	scratch family zinc finger 2	604	0.66
chr17_45969705_45969938	0.50	Gm49805	predicted gene, 49805	7962	0.18
chr11_78438435_78438586	0.50	Gm11195	predicted gene 11195	5597	0.1
chr10_111072134_111072302	0.50	Gm48851	predicted gene, 48851	30653	0.14
chr12_12788007_12788188	0.50	Platr19	pluripotency associated transcript 19	112	0.97
chr3_141797904_141798064	0.49	Unc5c	unc-5 netrin receptor C	8132	0.29
chr12_89156413_89157009	0.49	Nrxn3	neurexin III	36395	0.21
chr3_84257983_84258345	0.49	Trim2	tripartite motif-containing 2	1205	0.58
chr1_164321591_164321786	0.49	Nme7	NME/NM23 family member 7	8809	0.16
chr12_36207161_36207326	0.49	Lrrc72	leucine rich repeat containing 72	10959	0.14
chr5_119462792_119462943	0.49	Gm31314	predicted gene, 31314	65087	0.11
chr6_83207567_83207718	0.49	Dctn1	dynactin 1	10628	0.09
chr11_101277708_101277859	0.49	Wnk4	WNK lysine deficient protein kinase 4	1137	0.17
chr1_130682136_130682296	0.49	C4bp-ps1	complement component 4 binding protein, pseudogene 1	1855	0.21
chr11_97812508_97813039	0.48	Lasp1	LIM and SH3 protein 1	2475	0.14
chr11_53450169_53450320	0.48	Gm10447	predicted gene 10447	6866	0.08
chr10_7832159_7832334	0.48	Zc3h12d	zinc finger CCCH type containing 12D	224	0.88
chr7_89411407_89411749	0.48	Fzd4	frizzled class receptor 4	7223	0.14
chr19_6502922_6503256	0.47	Nrxn2	neurexin II	5254	0.13
chrX_164135402_164135726	0.47	n-R5s18	nuclear encoded rRNA 5S 18	2179	0.27
chr14_67072372_67072960	0.47	Ppp2r2a	protein phosphatase 2, regulatory subunit B, alpha	222	0.92
chr5_137502130_137503030	0.47	Pop7	processing of precursor 7, ribonuclease P family, (S. cerevisiae)	62	0.52
chr15_85613387_85614197	0.47	Wnt7b	wingless-type MMTV integration site family, member 7B	31319	0.12
chr11_98748745_98749452	0.47	Thra	thyroid hormone receptor alpha	4488	0.11
chr7_140059661_140059812	0.47	Msx3	msh homeobox 3	10647	0.09

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf5

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.2	0.6	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
0.2	0.5	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.1	0.5	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1	0.3	GO:0018992	germ-line sex determination(GO:0018992)
0.1	0.6	GO:0021563	glossopharyngeal nerve development(GO:0021563)
0.1	0.4	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1	0.5	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.1	0.3	GO:0006868	glutamine transport(GO:0006868)
0.1	1.2	GO:0097120	receptor localization to synapse(GO:0097120)
0.1	0.5	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.3	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.1	0.3	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.4	GO:0071896	protein localization to adherens junction(GO:0071896)
0.1	0.3	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1	0.3	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.1	0.2	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1	0.3	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.1	0.7	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.1	0.2	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.1	0.5	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1	0.2	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1	0.3	GO:0001951	intestinal D-glucose absorption(GO:0001951)
0.1	0.4	GO:0006776	vitamin A metabolic process(GO:0006776)
0.1	0.3	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.2	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.2	GO:0032439	endosome localization(GO:0032439)
0.1	0.8	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1	0.3	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.1	0.3	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1	0.4	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1	0.2	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.1	GO:0061642	chemoattraction of axon(GO:0061642)
0.1	0.2	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.1	0.1	GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.1	0.2	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.3	GO:0098598	vocal learning(GO:0042297) imitative learning(GO:0098596) learned vocalization behavior or vocal learning(GO:0098598)
0.1	0.2	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1	0.2	GO:0060535	trachea cartilage morphogenesis(GO:0060535)
0.1	0.2	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.1	0.2	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.1	0.3	GO:0070314	G1 to G0 transition(GO:0070314)
0.1	0.3	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.3	GO:0048194	Golgi vesicle budding(GO:0048194)
0.0	0.1	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.2	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0	0.1	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.1	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.1	GO:0071139	resolution of recombination intermediates(GO:0071139)
0.0	0.3	GO:0035989	tendon development(GO:0035989)
0.0	0.1	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0	0.2	GO:0010424	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.0	0.1	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.0	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.1	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.1	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.4	GO:0014807	regulation of somitogenesis(GO:0014807)
0.0	0.1	GO:0097155	fasciculation of sensory neuron axon(GO:0097155)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.2	GO:0070444	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.1	GO:0035483	gastric emptying(GO:0035483)
0.0	0.5	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.2	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.1	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.1	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.3	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.2	GO:0009597	detection of virus(GO:0009597)
0.0	0.1	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0	0.4	GO:0097369	sodium ion import(GO:0097369)
0.0	0.1	GO:0042167	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0	0.2	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0	0.3	GO:0010388	cullin deneddylation(GO:0010388)
0.0	0.1	GO:0003096	renal sodium ion transport(GO:0003096)
0.0	0.5	GO:0030322	stabilization of membrane potential(GO:0030322)
0.0	0.0	GO:0072221	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0	0.2	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0014738	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0	0.1	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.2	GO:0015838	amino-acid betaine transport(GO:0015838)
0.0	0.2	GO:0090336	positive regulation of brown fat cell differentiation(GO:0090336)
0.0	0.1	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.0	0.2	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.5	GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0	0.4	GO:0035641	locomotory exploration behavior(GO:0035641)
0.0	0.1	GO:0042701	progesterone secretion(GO:0042701)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.2	GO:0000820	regulation of glutamine family amino acid metabolic process(GO:0000820)
0.0	0.0	GO:0098597	observational learning(GO:0098597)
0.0	0.0	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:0010612	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.9	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0043134	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.0	0.1	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.2	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.4	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956)
0.0	0.2	GO:0070269	pyroptosis(GO:0070269)
0.0	0.1	GO:0016198	axon choice point recognition(GO:0016198)
0.0	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.1	GO:0034476	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0	0.1	GO:0090071	negative regulation of ribosome biogenesis(GO:0090071)
0.0	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.2	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:2000481	positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0	0.1	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.0	0.1	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0070668	mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0	0.1	GO:0034628	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0	0.1	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.1	GO:1902990	telomere maintenance via semi-conservative replication(GO:0032201) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0	0.1	GO:0002159	desmosome assembly(GO:0002159)
0.0	0.1	GO:0003358	noradrenergic neuron development(GO:0003358)
0.0	0.0	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.1	GO:0003051	angiotensin-mediated drinking behavior(GO:0003051)
0.0	0.0	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
0.0	0.1	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.2	GO:0035878	nail development(GO:0035878)
0.0	0.2	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.2	GO:0071625	vocalization behavior(GO:0071625)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.3	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.0	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0035582	sequestering of BMP in extracellular matrix(GO:0035582)
0.0	0.4	GO:0044130	negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0	0.5	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.0	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.1	GO:0045113	integrin biosynthetic process(GO:0045112) regulation of integrin biosynthetic process(GO:0045113)
0.0	0.1	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.0	0.1	GO:0036394	amylase secretion(GO:0036394)
0.0	0.3	GO:0042659	regulation of cell fate specification(GO:0042659)
0.0	0.1	GO:0003149	membranous septum morphogenesis(GO:0003149)
0.0	0.0	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.2	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0	0.1	GO:0042519	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.3	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.1	GO:0032349	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0	0.0	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.0	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.0	GO:1904179	positive regulation of adipose tissue development(GO:1904179)
0.0	0.3	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.1	GO:0014824	artery smooth muscle contraction(GO:0014824)
0.0	0.1	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.0	GO:0071725	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0	0.1	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.0	0.0	GO:0046959	habituation(GO:0046959)
0.0	0.1	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0032960	regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0007442	hindgut morphogenesis(GO:0007442)
0.0	0.1	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0060406	positive regulation of penile erection(GO:0060406)
0.0	0.1	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0	0.1	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0	0.1	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.0	GO:0035524	proline transmembrane transport(GO:0035524)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.2	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.0	0.1	GO:0051385	response to mineralocorticoid(GO:0051385)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.1	GO:0014028	notochord formation(GO:0014028)
0.0	0.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0014820	tonic smooth muscle contraction(GO:0014820)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.3	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.0	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.1	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.0	0.0	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.0	GO:0060685	regulation of prostatic bud formation(GO:0060685)
0.0	0.1	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.0	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.1	GO:0010226	response to lithium ion(GO:0010226)
0.0	0.1	GO:0018158	protein oxidation(GO:0018158)
0.0	0.1	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.0	GO:0030913	paranodal junction assembly(GO:0030913)
0.0	0.0	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0	0.1	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0045060	negative thymic T cell selection(GO:0045060)
0.0	0.0	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0	0.1	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.0	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.6	GO:0015807	L-amino acid transport(GO:0015807)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0	0.1	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.0	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0060534	trachea cartilage development(GO:0060534)
0.0	0.1	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:0003418	growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0	0.0	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.0	0.0	GO:0030070	insulin processing(GO:0030070)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0006116	NADH oxidation(GO:0006116)
0.0	0.0	GO:0014042	positive regulation of neuron maturation(GO:0014042) positive regulation of cell maturation(GO:1903431)
0.0	0.3	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.2	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0042905	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.0	GO:0009642	response to light intensity(GO:0009642)
0.0	0.1	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.2	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.0	0.0	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:1900273	positive regulation of long-term synaptic potentiation(GO:1900273)
0.0	0.1	GO:0046036	CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0	0.0	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.1	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.0	0.1	GO:0060416	response to growth hormone(GO:0060416)
0.0	0.4	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.0	0.0	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.0	0.3	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.0	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.0	0.5	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.0	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.0	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.0	0.0	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:0046103	inosine biosynthetic process(GO:0046103)
0.0	0.0	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.0	0.0	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.0	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.0	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.1	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.0	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.4	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.0	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.1	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.0	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.0	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.0	0.0	GO:0097503	sialylation(GO:0097503)
0.0	0.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.0	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.0	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.0	GO:0032484	Ral protein signal transduction(GO:0032484)
0.0	0.2	GO:0032401	establishment of melanosome localization(GO:0032401) melanosome transport(GO:0032402)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.0	GO:0097694	establishment of RNA localization to telomere(GO:0097694)
0.0	0.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0	0.1	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.0	0.0	GO:0030421	defecation(GO:0030421)
0.0	0.0	GO:0090394	negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.0	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0046541	saliva secretion(GO:0046541)
0.0	0.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.0	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.0	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.1	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.0	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
0.0	0.0	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.0	GO:1902473	regulation of protein localization to synapse(GO:1902473) positive regulation of protein localization to synapse(GO:1902474)
0.0	0.0	GO:2000391	regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0	0.0	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.0	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.0	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0	0.0	GO:0046125	pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.0	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.0	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.0	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.3	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.2	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0	0.0	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.0	0.1	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.2	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.1	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:2000705	regulation of dense core granule biogenesis(GO:2000705)
0.0	0.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.0	0.1	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.0	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0034435	steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.0	0.0	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:0046439	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.0	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.0	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:0046040	IMP metabolic process(GO:0046040)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	0.4	GO:0089701	U2AF(GO:0089701)
0.1	0.4	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.1	0.9	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.1	0.3	GO:0043202	lysosomal lumen(GO:0043202)
0.1	0.3	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1	0.2	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.1	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.2	GO:0033269	internode region of axon(GO:0033269)
0.1	0.2	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.2	GO:1990357	terminal web(GO:1990357)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	1.2	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.1	GO:0035061	interchromatin granule(GO:0035061)
0.0	0.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.3	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:1990246	uniplex complex(GO:1990246)
0.0	0.2	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.0	0.3	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.5	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.2	GO:0098563	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.3	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.3	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.3	GO:0098827	endoplasmic reticulum subcompartment(GO:0098827)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.2	GO:0005687	U4 snRNP(GO:0005687)
0.0	0.2	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	0.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.2	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.2	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.0	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.1	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.0	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.0	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0097422	tubular endosome(GO:0097422)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.0	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.1	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0001741	XY body(GO:0001741)
0.0	0.4	GO:0005771	multivesicular body(GO:0005771)
0.0	0.0	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.0	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.0	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.0	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	1.0	GO:0043296	apical junction complex(GO:0043296)
0.0	0.1	GO:0042581	specific granule(GO:0042581)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	0.5	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.1	0.3	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.1	0.3	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.1	0.6	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.1	0.3	GO:0030621	U4 snRNA binding(GO:0030621)
0.1	0.4	GO:0008865	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	0.3	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	0.2	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1	0.3	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.3	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1	0.3	GO:1904288	BAT3 complex binding(GO:1904288)
0.1	0.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1	0.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.2	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.1	0.4	GO:0050700	CARD domain binding(GO:0050700)
0.1	0.2	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.2	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.3	GO:0031419	cobalamin binding(GO:0031419)
0.1	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.3	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.0	1.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.0	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.0	0.2	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.3	GO:0000150	recombinase activity(GO:0000150)
0.0	0.3	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	0.2	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.6	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.2	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.2	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.3	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.2	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.2	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.0	0.2	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0042731	PH domain binding(GO:0042731)
0.0	1.1	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.7	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.0	GO:0004337	geranyltranstransferase activity(GO:0004337)
0.0	0.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.3	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.4	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.3	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.2	GO:0015368	calcium:cation antiporter activity(GO:0015368)
0.0	0.4	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	0.7	GO:0043738	N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.0	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.3	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.3	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.9	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0005412	glucose:sodium symporter activity(GO:0005412)
0.0	0.0	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.2	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.6	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.2	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.1	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0071987	WD40-repeat domain binding(GO:0071987)
0.0	0.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.0	GO:0019862	IgA binding(GO:0019862)
0.0	0.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0001588	dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0	0.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.1	GO:0018448	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0	0.1	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.0	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.0	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.0	GO:0031705	bombesin receptor binding(GO:0031705)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.0	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.1	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.0	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.0	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0001013	RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.0	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.3	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.1	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.1	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.1	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.0	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.0	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.1	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.0	GO:0070051	fibrinogen binding(GO:0070051)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.6	ST GAQ PATHWAY	G alpha q Pathway
0.8	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.7	PID ERBB4 PATHWAY	ErbB4 signaling events
0.5	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.7	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.2	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
1.2	PID CMYB PATHWAY	C-MYB transcription factor network
0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.4	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.3	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.1	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	0.2	REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES	Genes involved in Transmembrane transport of small molecules
0.1	1.2	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0	0.5	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.8	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.2	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.7	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.4	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.5	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.6	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.1	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.0	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.2	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.0	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.2	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.1	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.0	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.1	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac

Results for Atf5

Z-value: 0.92

Motif logo

Transcription factors associated with Atf5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Atf5 motif across conditions

Conditions sorted by the z-value of the Atf5 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: