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ENCODE: ATAC-seq of different tissues during embryonic development
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Results for Batf3

Z-value: 0.62

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Transcription factors associated with Batf3

Gene Symbol Gene ID Gene Info
Batf3
ENSMUSG00000026630.4 basic leucine zipper transcription factor, ATF-like 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_191097955_191098106Batf31500.924944-0.283.9e-02Click!
chr1_191098208_191098740Batf3910.947370-0.238.9e-02Click!
chr1_191111292_191111443Batf3108900.113908-0.143.0e-01Click!

Activity of the Batf3 motif across conditions

Conditions sorted by the z-value of the Batf3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_69709128_69709981 4.91 Rpl32-ps
 ribosomal protein L32, pseudogene
 7839
 0.17
chr1_165396068_165396234 3.55 Dcaf6
 DDB1 and CUL4 associated factor 6
 7390
 0.14
chr2_49730225_49730511 1.99 Kif5c
 kinesin family member 5C
 2243
 0.36
chr3_17793443_17793892 1.96 Mir124-2hg
 Mir124-2 host gene (non-protein coding)
 253
 0.9
chr7_142088957_142089418 1.92 Dusp8
 dual specificity phosphatase 8
 6085
 0.08
chr17_72399498_72399651 1.76 Gm24736
 predicted gene, 24736
 99844
 0.07
chr6_124464616_124464917 1.75 Clstn3
 calsyntenin 3
 28
 0.95
chr1_38446167_38446442 1.74 Gm34727
 predicted gene, 34727
 41215
 0.16
chr3_129536267_129536526 1.72 Gm43072
 predicted gene 43072
 1745
 0.29
chr8_70500802_70501205 1.68 Crlf1
 cytokine receptor-like factor 1
 130
 0.9
chr14_68048454_68048605 1.67 Gm31107
 predicted gene, 31107
 2801
 0.28
chr12_73286641_73287386 1.64 Slc38a6
 solute carrier family 38, member 6
 47
 0.81
chr14_87140676_87141090 1.61 Diaph3
 diaphanous related formin 3
 260
 0.93
chr6_57703265_57703437 1.60 Lancl2
 LanC (bacterial lantibiotic synthetase component C)-like 2
 264
 0.88
chr7_141146101_141146426 1.60 Ptdss2
 phosphatidylserine synthase 2
 8360
 0.08
chr13_65258166_65258818 1.59 Gm10775
 predicted gene 10775
 1047
 0.28
chr8_60954723_60954914 1.55 Clcn3
 chloride channel, voltage-sensitive 3
 39
 0.97
chr13_22042530_22043117 1.54 H2ac11
 H2A clustered histone 11
 121
 0.56
chr6_114659319_114659576 1.47 Atg7
 autophagy related 7
 1383
 0.51
chr7_97749679_97749846 1.46 Aqp11
 aquaporin 11
 11473
 0.16
chr4_142017787_142018051 1.42 4930455G09Rik
 RIKEN cDNA 4930455G09 gene
 21
 0.96
chr14_74972805_74972992 1.42 Gm4278
 predicted gene 4278
 2188
 0.3
chr7_128414880_128415076 1.40 Gm15503
 predicted gene 15503
 2637
 0.17
chr2_151563228_151563425 1.37 Sdcbp2
 syndecan binding protein (syntenin) 2
 9296
 0.13
chr11_103101909_103102424 1.37 Acbd4
 acyl-Coenzyme A binding domain containing 4
 440
 0.48
chrY_90771156_90771656 1.35 Gm47283
 predicted gene, 47283
 13332
 0.16
chr14_61680824_61681965 1.35 Gm37472
 predicted gene, 37472
 100
 0.9
chrX_169996827_169997318 1.34 Gm15247
 predicted gene 15247
 10133
 0.15
chr1_82836684_82836853 1.30 Gm22396
 predicted gene, 22396
 2678
 0.14
chr9_111534874_111535371 1.30 Gm42523
 predicted gene 42523
 13818
 0.19
chr3_96905206_96905674 1.28 Gpr89
 G protein-coupled receptor 89
 94
 0.91
chr12_3237774_3237992 1.26 Rab10os
 RAB10, member RAS oncogene family, opposite strand
 1272
 0.39
chr17_55892287_55892468 1.21 Zfp959
 zinc finger protein 959
 91
 0.95
chr15_27871362_27871539 1.18 Gm20555
 predicted gene, 20555
 4219
 0.22
chr17_55878572_55878762 1.18 Zfp119a
 zinc finger protein 119a
 263
 0.86
chr6_120807499_120807674 1.17 Atp6v1e1
 ATPase, H+ transporting, lysosomal V1 subunit E1
 5164
 0.15
chr18_44828099_44828778 1.15 Ythdc2
 YTH domain containing 2
 692
 0.64
chr9_123925253_123925437 1.13 Ccr1
 chemokine (C-C motif) receptor 1
 43347
 0.1
chr1_132322162_132322332 1.13 Nuak2
 NUAK family, SNF1-like kinase, 2
 5349
 0.13
chr1_179433930_179434100 1.12 Smyd3
 SET and MYND domain containing 3
 28596
 0.2
chr12_3238767_3239202 1.11 Rab10os
 RAB10, member RAS oncogene family, opposite strand
 2373
 0.24
chr10_63122610_63122870 1.11 Mypn
 myopalladin
 56
 0.96
chr3_17592524_17592749 1.10 Gm38154
 predicted gene, 38154
 78052
 0.11
chr2_129227265_129227416 1.10 A730036I17Rik
 RIKEN cDNA A730036I17 gene
 682
 0.4
chr6_115666689_115667030 1.10 Raf1
 v-raf-leukemia viral oncogene 1
 9105
 0.12
chr13_23760830_23761749 1.09 H4c1
 H4 clustered histone 1
 59
 0.86
chr8_79711585_79712295 1.07 Anapc10
 anaphase promoting complex subunit 10
 89
 0.65
chr16_75837887_75838038 1.05 Gm15554
 predicted gene 15554
 64905
 0.09
chr8_77548898_77549532 1.05 Prmt9
 protein arginine methyltransferase 9
 182
 0.92
chr1_184851887_184852286 1.04 Mtarc2
 mitochondrial amidoxime reducing component 2
 5635
 0.17
chr2_59351695_59352106 1.04 Pkp4
 plakophilin 4
 9703
 0.19
chr7_118463178_118463349 1.03 Syt17
 synaptotagmin XVII
 15041
 0.15
chr11_88242035_88242186 1.03 Gm38534
 predicted gene, 38534
 11258
 0.17
chr3_94484140_94484361 1.02 Celf3
 CUGBP, Elav-like family member 3
 77
 0.93
chr2_109280292_109280860 1.01 Mettl15
 methyltransferase like 15
 126
 0.55
chr16_10976223_10976631 1.00 Litaf
 LPS-induced TN factor
 848
 0.46
chr6_128799495_128800104 1.00 Klrb1c
 killer cell lectin-like receptor subfamily B member 1C
 10584
 0.1
chr1_75214435_75214934 0.98 Stk16
 serine/threonine kinase 16
 1623
 0.13
chr6_57822566_57822717 0.97 Vopp1
 vesicular, overexpressed in cancer, prosurvival protein 1
 1999
 0.23
chr12_84217180_84217402 0.96 Gm47447
 predicted gene, 47447
 1154
 0.3
chr2_127444443_127444898 0.96 Fahd2a
 fumarylacetoacetate hydrolase domain containing 2A
 105
 0.96
chr9_103234179_103234348 0.95 Trf
 transferrin
 3819
 0.2
chr3_82478392_82478716 0.95 Npy2r
 neuropeptide Y receptor Y2
 69406
 0.11
chr7_97788183_97788962 0.94 Pak1
 p21 (RAC1) activated kinase 1
 31
 0.98
chr12_100167000_100167151 0.93 Nrde2
 nrde-2 necessary for RNA interference, domain containing
 7422
 0.14
chr17_55944886_55945074 0.93 Zfp119b
 zinc finger protein 119b
 279
 0.8
chr8_66860040_66861058 0.90 Naf1
 nuclear assembly factor 1 ribonucleoprotein
 332
 0.88
chr9_7836413_7837486 0.90 Birc2
 baculoviral IAP repeat-containing 2
 108
 0.96
chr13_21935906_21936057 0.90 Zfp184
 zinc finger protein 184 (Kruppel-like)
 9113
 0.06
chrX_13070554_13071574 0.90 Usp9x
 ubiquitin specific peptidase 9, X chromosome
 434
 0.84
chr10_108333682_108333833 0.89 Pawr
 PRKC, apoptosis, WT1, regulator
 940
 0.6
chr6_86669349_86669907 0.88 Mxd1
 MAX dimerization protein 1
 467
 0.68
chr18_10939016_10939167 0.88 Gm7575
 predicted gene 7575
 10207
 0.23
chr18_9957690_9958213 0.88 Thoc1
 THO complex 1
 45
 0.97
chr11_4250427_4250602 0.87 Lif
 leukemia inhibitory factor
 7043
 0.1
chr13_113168382_113168574 0.87 Gzmk
 granzyme K
 12419
 0.12
chr7_80324088_80324301 0.85 Rccd1
 RCC1 domain containing 1
 41
 0.95
chr16_57606439_57606962 0.84 Cmss1
 cms small ribosomal subunit 1
 76
 0.98
chr7_138846157_138846363 0.84 Mapk1ip1
 mitogen-activated protein kinase 1 interacting protein 1
 0
 0.58
chr4_63374024_63374199 0.84 Akna
 AT-hook transcription factor
 7092
 0.11
chr2_93096177_93096364 0.83 Gm13802
 predicted gene 13802
 1974
 0.37
chr9_69467648_69467967 0.82 Anxa2
 annexin A2
 10658
 0.12
chr7_16296088_16297248 0.82 Ccdc9
 coiled-coil domain containing 9
 9873
 0.11
chr9_64178981_64179377 0.81 Snapc5
 small nuclear RNA activating complex, polypeptide 5
 95
 0.89
chr6_35173300_35173451 0.79 Nup205
 nucleoporin 205
 4046
 0.24
chr11_20200843_20201200 0.79 Rab1a
 RAB1A, member RAS oncogene family
 411
 0.82
chr3_40799878_40800077 0.79 Plk4
 polo like kinase 4
 42
 0.96
chr17_88113373_88113524 0.78 Gm4832
 predicted gene 4832
 12064
 0.18
chr17_28013289_28013809 0.77 Anks1
 ankyrin repeat and SAM domain containing 1
 6204
 0.13
chr1_92473261_92473440 0.77 Ndufa10
 NADH:ubiquinone oxidoreductase subunit A10
 397
 0.76
chr17_53596429_53596797 0.76 Gm6919
 predicted gene 6919
 2050
 0.27
chr4_63389695_63390110 0.75 Aknaos
 AT-hook transcription factor, opposite strand
 8544
 0.12
chr4_116175694_116176193 0.75 Gm12951
 predicted gene 12951
 303
 0.78
chr8_4779223_4779832 0.74 Shcbp1
 Shc SH2-domain binding protein 1
 24
 0.95
chr3_105483711_105484059 0.74 Gm43847
 predicted gene 43847
 19022
 0.17
chr2_129242545_129242834 0.74 Gm14024
 predicted gene 14024
 3687
 0.12
chr7_16399506_16399684 0.74 Zc3h4
 zinc finger CCCH-type containing 4
 1315
 0.27
chr14_30876254_30876405 0.74 Mustn1
 musculoskeletal, embryonic nuclear protein 1
 2871
 0.16
chrX_56597885_56598283 0.73 Mmgt1
 membrane magnesium transporter 1
 15
 0.97
chr5_130706297_130706454 0.73 Gm23761
 predicted gene, 23761
 76326
 0.1
chr1_161766742_161767051 0.73 Gm5049
 predicted gene 5049
 20840
 0.12
chr2_120609238_120609778 0.73 Lrrc57
 leucine rich repeat containing 57
 0
 0.56
chr19_61227192_61227555 0.73 Csf2ra
 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
 3
 0.96
chr1_75168558_75168746 0.73 Zfand2b
 zinc finger, AN1 type domain 2B
 3
 0.93
chr11_121086446_121086616 0.72 Sectm1a
 secreted and transmembrane 1A
 5311
 0.09
chr19_24961254_24961969 0.72 Cbwd1
 COBW domain containing 1
 1
 0.97
chr18_12786714_12786865 0.71 Osbpl1a
 oxysterol binding protein-like 1A
 19652
 0.15
chr7_99795341_99796009 0.71 F730035P03Rik
 RIKEN cDNA F730035P03 gene
 14136
 0.11
chr6_49263929_49264218 0.71 Tra2a
 transformer 2 alpha
 40
 0.97
chr3_34231745_34231896 0.70 Sox2ot
 SOX2 overlapping transcript (non-protein coding)
 34956
 0.16
chr10_59777356_59777560 0.70 Micu1
 mitochondrial calcium uptake 1
 15045
 0.14
chr13_67360105_67360768 0.70 Gm28044
 predicted gene, 28044
 100
 0.47
chr13_97775152_97775346 0.69 Rps18-ps6
 ribosomal protein S18, pseudogene 6
 14617
 0.14
chr1_92473653_92474522 0.69 Ndufa10
 NADH:ubiquinone oxidoreductase subunit A10
 227
 0.88
chr12_75307963_75308582 0.69 Rhoj
 ras homolog family member J
 50
 0.99
chr7_7298676_7299288 0.69 Mir5620
 microRNA 5620
 91
 0.61
chr5_123854595_123854839 0.68 Hcar2
 hydroxycarboxylic acid receptor 2
 10782
 0.13
chr10_111073345_111073645 0.68 Gm48851
 predicted gene, 48851
 29376
 0.14
chr4_41708277_41708428 0.68 Rpp25l
 ribonuclease P/MRP 25 subunit-like
 5182
 0.1
chr8_84256509_84256688 0.68 Mri1
 methylthioribose-1-phosphate isomerase 1
 185
 0.87
chr10_82240724_82241110 0.67 Zfp938
 zinc finger protein 938
 356
 0.84
chr16_38562668_38563355 0.66 Tmem39a
 transmembrane protein 39a
 125
 0.95
chr9_71976147_71976576 0.66 Gm37663
 predicted gene, 37663
 14910
 0.1
chr9_14246488_14246694 0.66 Gm47565
 predicted gene, 47565
 4348
 0.18
chr7_135813684_135813871 0.66 6330420H09Rik
 RIKEN cDNA 6330420H09 gene
 39905
 0.12
chr5_89763970_89764289 0.66 Gm25758
 predicted gene, 25758
 64742
 0.13
chr2_20944134_20944558 0.66 Arhgap21
 Rho GTPase activating protein 21
 927
 0.58
chr2_69722689_69722921 0.66 Ppig
 peptidyl-prolyl isomerase G (cyclophilin G)
 0
 0.96
chr5_24383104_24384088 0.66 Gm15587
 predicted gene 15587
 14
 0.94
chr15_13171596_13171768 0.66 Cdh6
 cadherin 6
 1993
 0.47
chrX_101290140_101290457 0.65 Med12
 mediator complex subunit 12
 2836
 0.13
chr1_161036007_161036172 0.65 Gm22357
 predicted gene, 22357
 32
 0.41
chr11_29607584_29607776 0.65 Gm12091
 predicted gene 12091
 5067
 0.14
chr4_154603637_154604075 0.64 Gm13134
 predicted gene 13134
 2541
 0.22
chr17_57098452_57098603 0.63 Tnfsf9
 tumor necrosis factor (ligand) superfamily, member 9
 6798
 0.08
chr12_86883989_86885134 0.63 Irf2bpl
 interferon regulatory factor 2 binding protein-like
 237
 0.93
chr2_180892991_180893395 0.63 Mir124a-3
 microRNA 124a-3
 847
 0.31
chr2_122380827_122380978 0.63 Gm24409
 predicted gene, 24409
 4738
 0.15
chr9_106170484_106171031 0.62 Wdr82
 WD repeat domain containing 82
 171
 0.89
chr2_15054565_15055405 0.62 Nsun6
 NOL1/NOP2/Sun domain family member 6
 84
 0.72
chr6_21949203_21949798 0.61 Ing3
 inhibitor of growth family, member 3
 71
 0.98
chr7_7299356_7299778 0.61 Clcn4
 chloride channel, voltage-sensitive 4
 10
 0.91
chr7_4149205_4149990 0.61 Leng9
 leukocyte receptor cluster (LRC) member 9
 777
 0.41
chr2_125122926_125123420 0.61 Myef2
 myelin basic protein expression factor 2, repressor
 241
 0.89
chr2_112454615_112455124 0.61 Emc7
 ER membrane protein complex subunit 7
 128
 0.94
chr17_84877971_84878140 0.60 Gm49982
 predicted gene, 49982
 24514
 0.14
chr15_7137719_7137966 0.60 Lifr
 LIF receptor alpha
 2700
 0.38
chr2_144343181_144343332 0.60 Ovol2
 ovo like zinc finger 2
 11110
 0.1
chr13_67724281_67724474 0.60 Zfp65
 zinc finger protein 65
 51
 0.92
chr1_134454955_134455620 0.60 Gm37935
 predicted gene, 37935
 186
 0.56
chr6_91440817_91441099 0.60 1810044D09Rik
 RIKEN cDNA 1810044D09 gene
 29
 0.5
chr4_156054432_156054595 0.59 Mir200a
 microRNA 200a
 472
 0.37
chr10_126749213_126749376 0.59 Gm47966
 predicted gene, 47966
 29900
 0.12
chr18_66458401_66458670 0.59 Pmaip1
 phorbol-12-myristate-13-acetate-induced protein 1
 2
 0.96
chr8_69625175_69625427 0.59 Zfp868
 zinc finger protein 868
 244
 0.91
chrX_8176094_8176317 0.59 Tbc1d25
 TBC1 domain family, member 25
 24
 0.95
chr1_59237629_59237969 0.58 Als2
 alsin Rho guanine nucleotide exchange factor
 568
 0.74
chr2_120153745_120155075 0.58 Ehd4
 EH-domain containing 4
 52
 0.97
chr1_166409714_166410315 0.57 Pogk
 pogo transposable element with KRAB domain
 151
 0.94
chr16_50046157_50046358 0.57 Gm8824
 predicted gene 8824
 64816
 0.14
chr11_116572806_116573131 0.57 Ube2o
 ubiquitin-conjugating enzyme E2O
 8479
 0.1
chr3_104795762_104796004 0.57 Rhoc
 ras homolog family member C
 3900
 0.11
chr17_63784808_63784959 0.57 Fer
 fer (fms/fps related) protein kinase
 78179
 0.09
chr19_43898677_43898828 0.57 Dnmbp
 dynamin binding protein
 8061
 0.14
chr3_127552930_127553443 0.56 Larp7
 La ribonucleoprotein domain family, member 7
 11
 0.79
chr2_122377386_122377671 0.56 Gm24409
 predicted gene, 24409
 8112
 0.13
chr10_44268190_44268842 0.56 Atg5
 autophagy related 5
 101
 0.97
chr4_46041817_46041999 0.56 Tmod1
 tropomodulin 1
 2699
 0.27
chr19_61228253_61228788 0.55 Csf2ra
 colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
 91
 0.95
chr1_137900910_137901218 0.55 Gm4258
 predicted gene 4258
 2466
 0.14
chrX_155216720_155216871 0.55 Sat1
 spermidine/spermine N1-acetyl transferase 1
 346
 0.82
chr1_171375937_171376095 0.54 Nectin4
 nectin cell adhesion molecule 4
 5661
 0.07
chr2_30929577_30930014 0.54 Ptges
 prostaglandin E synthase
 68
 0.96
chr5_32196023_32196194 0.54 Gm9555
 predicted gene 9555
 10611
 0.15
chr18_80151657_80151990 0.53 Adnp2
 ADNP homeobox 2
 341
 0.77
chr13_23530854_23531458 0.53 H4c8
 H4 clustered histone 8
 106
 0.6
chr5_36691557_36691708 0.51 D5Ertd579e
 DNA segment, Chr 5, ERATO Doi 579, expressed
 4305
 0.16
chr5_33018563_33018867 0.51 Ywhah
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
 101
 0.96
chrX_16618200_16618385 0.51 Maoa
 monoamine oxidase A
 1406
 0.48
chr10_82354457_82354651 0.51 Gm4924
 predicted gene 4924
 238
 0.92
chr7_27675038_27675234 0.51 Map3k10
 mitogen-activated protein kinase kinase kinase 10
 538
 0.6
chr1_59394147_59394298 0.51 Gm29016
 predicted gene 29016
 15292
 0.18
chr4_89310510_89311260 0.49 Cdkn2b
 cyclin dependent kinase inhibitor 2B
 154
 0.95
chr9_37177686_37177862 0.49 Gm25273
 predicted gene, 25273
 4780
 0.14
chr14_62446475_62446626 0.48 Gucy1b2
 guanylate cyclase 1, soluble, beta 2
 8243
 0.18
chr13_55425993_55426144 0.48 F12
 coagulation factor XII (Hageman factor)
 711
 0.46
chr17_84466117_84466668 0.48 Thada
 thyroid adenoma associated
 187
 0.95
chrX_162902264_162902478 0.47 Ctps2
 cytidine 5'-triphosphate synthase 2
 200
 0.91
chr12_82225804_82226178 0.45 Sipa1l1
 signal-induced proliferation-associated 1 like 1
 30594
 0.19
chr14_77034576_77034752 0.44 Lacc1
 laccase domain containing 1
 1417
 0.39
chr2_153161013_153161878 0.43 Tm9sf4
 transmembrane 9 superfamily protein member 4
 96
 0.96
chr14_50807340_50808013 0.43 Ccnb1ip1
 cyclin B1 interacting protein 1
 56
 0.42
chr11_116657908_116658166 0.43 Prcd
 photoreceptor disc component
 881
 0.36
chr13_83737818_83738360 0.42 Gm33366
 predicted gene, 33366
 446
 0.49
chr10_81602742_81603198 0.42 Tle6
 transducin-like enhancer of split 6
 1897
 0.15
chr1_75210411_75211182 0.42 Glb1l
 galactosidase, beta 1-like
 17
 0.49
chr12_98628022_98628216 0.42 Spata7
 spermatogenesis associated 7
 38
 0.96
chr13_100871561_100871718 0.41 Gm37830
 predicted gene, 37830
 1141
 0.42
chr6_108706138_108706289 0.41 Bhlhe40
 basic helix-loop-helix family, member e40
 43167
 0.12
chrX_104293744_104293895 0.41 Vcp-rs
 valosin containing protein, related sequence
 54415
 0.12

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Batf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0048388 endosomal lumen acidification(GO:0048388)
0.5 1.4 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.3 1.7 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.3 1.3 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.3 0.9 GO:0048290 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.3 0.8 GO:0061535 glutamate secretion, neurotransmission(GO:0061535)
0.3 1.5 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 0.7 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 0.6 GO:0043134 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.2 0.7 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.2 0.7 GO:0098535 de novo centriole assembly(GO:0098535)
0.2 0.8 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 0.8 GO:0006824 cobalt ion transport(GO:0006824)
0.1 0.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.4 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.7 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.7 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.6 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.8 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.1 0.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.7 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.1 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.3 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 0.4 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.5 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 0.2 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.8 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.2 GO:0002254 kinin cascade(GO:0002254)
0.1 0.2 GO:2000019 negative regulation of male gonad development(GO:2000019)
0.1 0.3 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.3 GO:0033753 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.1 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.2 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.1 0.2 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.1 0.4 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.2 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.5 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.4 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.5 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.8 GO:1904872 regulation of telomerase RNA localization to Cajal body(GO:1904872) positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.1 0.2 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.1 0.2 GO:0097460 ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460)
0.1 0.2 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.1 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.1 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.2 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.2 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.4 GO:0050957 equilibrioception(GO:0050957)
0.0 1.1 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 0.1 GO:0010963 regulation of L-arginine import(GO:0010963)
0.0 1.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.6 GO:0006907 pinocytosis(GO:0006907)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.6 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.5 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 1.0 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.1 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.4 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.5 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889)
0.0 0.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.1 GO:2001170 negative regulation of ATP biosynthetic process(GO:2001170)
0.0 0.0 GO:0044805 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:0000059 protein import into nucleus, docking(GO:0000059)
0.0 0.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.2 GO:0006266 DNA ligation(GO:0006266)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.2 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.0 GO:0070350 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0 0.0 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.0 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.0 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.0 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.3 GO:0071549 response to dexamethasone(GO:0071548) cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:1902570 protein localization to nucleolus(GO:1902570) regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.5 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.5 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.4 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.0 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.0 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.6 GO:0006953 acute-phase response(GO:0006953)
0.0 0.0 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.0 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0007614 short-term memory(GO:0007614)
0.0 0.0 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.0 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.0 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 1.3 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.0 GO:0009219 pyrimidine deoxyribonucleotide metabolic process(GO:0009219) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.1 GO:0001842 neural fold formation(GO:0001842)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 0.0 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.0 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.0 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.0 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.0 GO:2000041 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0 0.0 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.8 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.0 GO:0019086 late viral transcription(GO:0019086)
0.0 0.1 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.4 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0071435 potassium ion export(GO:0071435)
0.0 0.0 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.0 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 1.0 GO:0008213 protein methylation(GO:0006479) protein alkylation(GO:0008213)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.0 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.0 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.1 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694)
0.0 0.2 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.0 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.2 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 0.7 GO:0098536 deuterosome(GO:0098536)
0.1 0.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.5 GO:0042581 specific granule(GO:0042581)
0.1 0.5 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.6 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.3 GO:0035363 histone locus body(GO:0035363)
0.1 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.8 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.8 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 1.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0005914 spot adherens junction(GO:0005914)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.7 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 1.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 1.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.9 GO:0030018 Z disc(GO:0030018)
0.0 0.0 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 1.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 0.7 GO:0015087 cobalt ion transmembrane transporter activity(GO:0015087)
0.2 0.5 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 0.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 2.0 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.1 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.4 GO:0019808 polyamine binding(GO:0019808)
0.1 0.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.6 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 0.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.1 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.8 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.8 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 0.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.2 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.9 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.2 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.9 GO:0052770 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 2.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.6 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 1.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.0 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.0 0.1 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0052794 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.0 GO:0004096 catalase activity(GO:0004096)
0.0 0.0 GO:0019976 interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.0 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.0 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.0 GO:0015232 heme transporter activity(GO:0015232)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.5 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.8 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.0 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions