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ENCODE: ATAC-seq of different tissues during embryonic development

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Results for Bhlhe40

Z-value: 1.82

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Transcription factors associated with Bhlhe40

Gene Symbol	Gene ID	Gene Info
Bhlhe40 Ensembl NCBI MGI UniProt	ENSMUSG00000030103.5	basic helix-loop-helix family, member e40

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_108700724_108701019	Bhlhe40	37825	0.130116	0.52	5.0e-05	Click!
chr6_108701060_108701211	Bhlhe40	38089	0.129695	0.52	5.1e-05	Click!
chr6_108709276_108709427	Bhlhe40	46305	0.116353	0.38	4.3e-03	Click!
chr6_108670955_108671106	Bhlhe40	7984	0.168519	-0.37	5.2e-03	Click!
chr6_108706138_108706289	Bhlhe40	43167	0.121482	-0.34	1.1e-02	Click!

Activity of the Bhlhe40 motif across conditions

Conditions sorted by the z-value of the Bhlhe40 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_153495771_153496762	8.87	4930404H24Rik	RIKEN cDNA 4930404H24 gene	3476	0.22
chr10_95618546_95618735	8.26	Gm33336	predicted gene, 33336	13599	0.13
chr1_191224278_191225037	7.87	D730003I15Rik	RIKEN cDNA D730003I15 gene	183	0.92
chr11_6597201_6597589	7.63	Nacad	NAC alpha domain containing	1997	0.16
chr19_14776884_14777035	7.38	Gm26026	predicted gene, 26026	58479	0.15
chr10_78464271_78465733	6.98	Pdxk	pyridoxal (pyridoxine, vitamin B6) kinase	27	0.93
chr9_91365711_91366045	6.60	Zic1	zinc finger protein of the cerebellum 1	68	0.95
chr9_123853201_123853461	5.89	Fyco1	FYVE and coiled-coil domain containing 1	1432	0.32
chr13_101286621_101286808	5.89	4932411K12Rik	RIKEN cDNA 4932411K12 gene	32395	0.17
chr18_12168289_12168858	5.71	Rmc1	regulator of MON1-CCZ1	144	0.94
chr14_79444694_79444858	5.71	Kbtbd6	kelch repeat and BTB (POZ) domain containing 6	7059	0.14
chr15_83897404_83897573	5.71	Efcab6	EF-hand calcium binding domain 6	13847	0.22
chr19_43626276_43626448	5.69	Gm22646	predicted gene, 22646	3916	0.13
chr13_83736071_83736420	5.63	Gm33366	predicted gene, 33366	2290	0.18
chr13_78179260_78179727	5.35	Gm38604	predicted gene, 38604	3666	0.16
chr10_81176405_81177305	5.33	Eef2	eukaryotic translation elongation factor 2	224	0.79
chr14_76531135_76531299	5.27	E130202H07Rik	RIKEN cDNA E130202H07 gene	4601	0.22
chrX_136138821_136139124	5.24	Bex4	brain expressed X-linked 4	24	0.96
chr14_118796195_118796694	5.17	Cldn10	claudin 10	8526	0.16
chr2_73093042_73093445	5.13	Gm13665	predicted gene 13665	23505	0.16
chr8_48224421_48225088	5.12	Gm32842	predicted gene, 32842	46231	0.16
chr14_33684010_33684237	5.06	Gm26228	predicted gene, 26228	39628	0.15
chr1_82837714_82837894	5.04	Gm22396	predicted gene, 22396	1642	0.19
chr13_48013586_48013800	5.03	4931429P17Rik	RIKEN cDNA 4931429P17 gene	4915	0.25
chrX_136215393_136215720	5.00	Bex1	brain expressed X-linked 1	43	0.92
chrX_152656185_152656553	4.94	Shroom2	shroom family member 2	11826	0.22
chr16_35769247_35769628	4.94	Slc49a4	solute carrier family 49 member 4	81	0.93
chr6_87615729_87615921	4.78	Gm34312	predicted gene, 34312	18078	0.12
chrX_135210164_135210824	4.76	Tceal6	transcription elongation factor A (SII)-like 6	193	0.92
chr14_41013489_41013965	4.70	Prxl2a	peroxiredoxin like 2A	44	0.97
chr17_56139506_56139883	4.57	Sema6b	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	649	0.5
chr5_90338323_90338474	4.51	Ankrd17	ankyrin repeat domain 17	1345	0.45
chr6_64688756_64688954	4.48	Grid2	glutamate receptor, ionotropic, delta 2	25667	0.22
chr15_40169638_40170055	4.47	Gm33301	predicted gene, 33301	7239	0.19
chr1_84710201_84710701	4.42	Dner	delta/notch-like EGF repeat containing	14230	0.15
chr18_6489931_6490203	4.40	Gm28529	predicted gene 28529	76	0.87
chr13_109569134_109569362	4.39	Pde4d	phosphodiesterase 4D, cAMP specific	12157	0.32
chr7_98579948_98580099	4.37	Emsy	EMSY, BRCA2-interacting transcriptional repressor	14212	0.15
chr3_30792734_30793388	4.35	Sec62	SEC62 homolog (S. cerevisiae)	186	0.78
chr5_110102028_110102516	4.33	Plcxd1	phosphatidylinositol-specific phospholipase C, X domain containing 1	1068	0.31
chr3_38568713_38568864	4.31	Gm7824	predicted gene 7824	10120	0.18
chr8_35707907_35708195	4.19	1700015I17Rik	RIKEN cDNA 1700015I17 gene	11898	0.15
chrX_153832343_153832567	4.18	Spin2c	spindlin family, member 2C	162	0.96
chr13_84448589_84449243	4.15	Gm26927	predicted gene, 26927	108803	0.07
chr7_27196124_27196735	4.10	Snrpa	small nuclear ribonucleoprotein polypeptide A	158	0.79
chr6_6851296_6851447	4.08	Gm44094	predicted gene, 44094	4880	0.15
chr14_76649991_76650289	4.08	Fkbp1a-ps1	FK506 binding protein 1a, pseudogene 1	13276	0.2
chr1_119471932_119472097	4.07	Ralb	v-ral simian leukemia viral oncogene B	6065	0.16
chr3_10439292_10440192	4.06	Snx16	sorting nexin 16	345	0.89
chr1_171033237_171033414	4.06	Gm26110	predicted gene, 26110	5360	0.1
chr10_103368584_103369060	3.98	Slc6a15	solute carrier family 6 (neurotransmitter transporter), member 15	979	0.63
chr17_50037206_50037357	3.97	Rftn1	raftlin lipid raft linker 1	57051	0.11
chr9_41011522_41012361	3.87	Crtam	cytotoxic and regulatory T cell molecule	7313	0.19
chr7_98103362_98104288	3.87	Myo7a	myosin VIIA	464	0.82
chr1_143739965_143740445	3.83	Glrx2	glutaredoxin 2 (thioltransferase)	170	0.94
chr19_34922684_34922914	3.81	Kif20b	kinesin family member 20B	365	0.87
chr2_168678724_168679270	3.78	Atp9a	ATPase, class II, type 9A	8651	0.21
chr18_60526023_60526223	3.69	Dctn4	dynactin 4	62	0.97
chr17_21962397_21962894	3.66	Zfp943	zinc finger prtoein 943	59	0.65
chr10_117417457_117417766	3.66	Gm40770	predicted gene, 40770	3707	0.17
chr16_45158549_45159450	3.65	Atg3	autophagy related 3	214	0.59
chr14_72602911_72603221	3.56	Fndc3a	fibronectin type III domain containing 3A	104	0.97
chr4_9560854_9561005	3.56	Asph	aspartate-beta-hydroxylase	34760	0.2
chr5_136170136_136170778	3.51	Orai2	ORAI calcium release-activated calcium modulator 2	171	0.91
chr12_85619875_85620071	3.50	Jdp2	Jun dimerization protein 2	17751	0.14
chr3_107278812_107279313	3.47	Lamtor5	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	63	0.96
chr6_127319063_127319538	3.47	Gm43636	predicted gene 43636	959	0.44
chr6_34176448_34176636	3.47	Slc35b4	solute carrier family 35, member B4	428	0.81
chr10_62486624_62487492	3.43	Vps26a	VPS26 retromer complex component A	253	0.89
chr6_144772609_144772760	3.40	Sox5	SRY (sex determining region Y)-box 5	9235	0.18
chr6_115838153_115838326	3.36	Efcab12	EF-hand calcium binding domain 12	173	0.89
chr17_15990334_15990898	3.35	Eif3s6-ps3	eukaryotic translation initiation factor 3, subunit 6, pseudogene 3	145336	0.04
chr10_86685163_86685353	3.34	1810014B01Rik	RIKEN cDNA 1810014B01 gene	267	0.78
chr1_151096209_151096442	3.33	Gm19087	predicted gene, 19087	11590	0.13
chr9_87255233_87255430	3.33	Cep162	centrosomal protein 162	43	0.98
chr19_17136664_17136840	3.32	Prune2	prune homolog 2	14	0.99
chr3_10127534_10127829	3.31	Gm37308	predicted gene, 37308	37726	0.1
chrX_134751293_134751577	3.28	Armcx6	armadillo repeat containing, X-linked 6	18	0.95
chr1_176934461_176934612	3.20	Gm15423	predicted gene 15423	1825	0.27
chr7_49120514_49120692	3.19	9130015G15Rik	RIKEN cDNA 9130015G15 gene	13673	0.19
chr16_97171631_97171795	3.18	Dscam	DS cell adhesion molecule	961	0.7
chr13_114478386_114478660	3.17	Fst	follistatin	19572	0.15
chr7_44382547_44382866	3.15	Syt3	synaptotagmin III	1396	0.19
chr2_118373026_118374430	3.12	Gpr176	G protein-coupled receptor 176	309	0.87
chr3_137775065_137775240	3.09	Mir6380	microRNA 6380	8463	0.15
chr10_83019897_83020322	3.01	Gm10773	predicted gene 10773	11586	0.19
chr2_60037329_60037536	2.99	Gm13572	predicted gene 13572	291	0.9
chr14_32321782_32322361	2.98	Ogdhl	oxoglutarate dehydrogenase-like	52	0.96
chr4_34882843_34883117	2.96	Zfp292	zinc finger protein 292	20	0.97
chr10_63338911_63339659	2.93	Sirt1	sirtuin 1	250	0.88
chr8_11915109_11915483	2.92	Gm45680	predicted gene 45680	33001	0.12
chr2_137939077_137939470	2.91	Gm14062	predicted gene 14062	62442	0.16
chr1_153737821_153737972	2.91	C230024C17Rik	RIKEN cDNA C230024C17 gene	67	0.94
chr13_63573352_63573844	2.91	Ptch1	patched 1	0	0.96
chrX_152326967_152327328	2.91	Kantr	Kdm5c adjacent non-coding transcript	316	0.86
chr14_63122133_63122583	2.84	Ctsb	cathepsin B	104	0.95
chr9_41073622_41073978	2.83	Ubash3b	ubiquitin associated and SH3 domain containing, B	5706	0.19
chr13_83744885_83745867	2.82	C130071C03Rik	RIKEN cDNA C130071C03 gene	6513	0.13
chr1_30873870_30874073	2.80	Phf3	PHD finger protein 3	50	0.97
chr4_57039494_57039672	2.79	Epb41l4b	erythrocyte membrane protein band 4.1 like 4b	11907	0.21
chr13_51570216_51570367	2.78	Shc3	src homology 2 domain-containing transforming protein C3	804	0.69
chr10_81232562_81232915	2.78	Zfr2	zinc finger RNA binding protein 2	417	0.59
chr10_128923395_128923597	2.76	Bloc1s1	biogenesis of lysosomal organelles complex-1, subunit 1	28	0.89
chr11_32287518_32287702	2.73	Hbq1b	hemoglobin, theta 1B	609	0.57
chr12_117042891_117043063	2.72	Gm10421	predicted gene 10421	108238	0.07
chr4_155895322_155895503	2.69	Acap3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	3100	0.1
chr2_74974713_74974872	2.65	n-R5s198	nuclear encoded rRNA 5S 198	39278	0.14
chr17_53478611_53479358	2.65	Rab5a	RAB5A, member RAS oncogene family	250	0.89
chr2_35507382_35507541	2.64	Gm35202	predicted gene, 35202	3930	0.16
chr11_70970609_70971178	2.58	Rpain	RPA interacting protein	364	0.67
chrX_68677949_68678679	2.58	Fmr1	fragile X mental retardation 1	227	0.92
chr8_61387522_61387989	2.56	Gm7432	predicted gene 7432	6368	0.2
chr2_178257009_178257425	2.55	Phactr3	phosphatase and actin regulator 3	64133	0.12
chr7_45796984_45797258	2.53	Lmtk3	lemur tyrosine kinase 3	9373	0.07
chr10_81059624_81060601	2.53	Sgta	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	3	0.94
chr5_72259400_72259551	2.53	Atp10d	ATPase, class V, type 10D	5169	0.21
chr10_85829043_85829227	2.49	Pwp1	PWP1 homolog, endonuclein	359	0.58
chr8_109464714_109464884	2.49	Pmfbp1	polyamine modulated factor 1 binding protein 1	29228	0.16
chr18_23394845_23395028	2.47	Dtna	dystrobrevin alpha	20199	0.27
chr18_82568393_82568575	2.47	Mbp	myelin basic protein	5222	0.19
chr8_94734148_94734373	2.47	Ccl22	chemokine (C-C motif) ligand 22	11330	0.12
chr5_146712366_146712611	2.43	4930573C15Rik	RIKEN cDNA 4930573C15 gene	5866	0.19
chr8_92545416_92545576	2.43	Gm45336	predicted gene 45336	79729	0.09
chr5_64360604_64360755	2.39	Gm43838	predicted gene 43838	165	0.94
chr7_113799049_113799200	2.36	Spon1	spondin 1, (f-spondin) extracellular matrix protein	32950	0.18
chr1_167270814_167271200	2.36	Uck2	uridine-cytidine kinase 2	13594	0.11
chr17_15041419_15041766	2.35	Ermard	ER membrane associated RNA degradation	23	0.38
chr10_43742673_43743096	2.35	Gm40634	predicted gene, 40634	203	0.91
chr8_77534450_77534755	2.35	Prmt9	protein arginine methyltransferase 9	14795	0.13
chr12_65036191_65036838	2.34	Prpf39	pre-mRNA processing factor 39	148	0.93
chr12_3930272_3930423	2.34	Gm9088	predicted gene 9088	1693	0.3
chr14_57746066_57746246	2.31	Lats2	large tumor suppressor 2	33	0.51
chr17_14202170_14202839	2.29	Gm34510	predicted gene, 34510	1224	0.37
chr5_93290462_93290662	2.29	Ccng2	cyclin G2	21854	0.17
chr18_61707863_61708185	2.28	Pcyox1l	prenylcysteine oxidase 1 like	389	0.76
chr2_158794072_158795253	2.28	Dhx35	DEAH (Asp-Glu-Ala-His) box polypeptide 35	145	0.96
chr2_130424198_130424383	2.26	Pced1a	PC-esterase domain containing 1A	9	0.51
chr11_53350270_53350813	2.25	Aff4	AF4/FMR2 family, member 4	292	0.84
chr14_79773979_79774403	2.25	Pcdh8	protocadherin 8	2879	0.2
chr8_39152774_39153465	2.24	Gm20948	predicted gene, 20948	47930	0.13
chr3_67557218_67557388	2.23	Gm35299	predicted gene, 35299	3878	0.15
chr14_100103888_100104073	2.22	Klf12	Kruppel-like factor 12	45784	0.17
chr9_44288848_44289229	2.21	Abcg4	ATP binding cassette subfamily G member 4	423	0.59
chr4_42943208_42943374	2.21	Phf24	PHD finger protein 24	5037	0.13
chr2_117123108_117123294	2.20	Spred1	sprouty protein with EVH-1 domain 1, related sequence	1563	0.44
chr14_123661372_123661538	2.19	Itgbl1	integrin, beta-like 1	31	0.98
chr19_5610231_5610544	2.19	Kat5	K(lysine) acetyltransferase 5	150	0.89
chr11_119897233_119897423	2.19	Chmp6	charged multivesicular body protein 6	16113	0.13
chr16_77885099_77885368	2.19	Gm17333	predicted gene, 17333	38629	0.18
chr16_35770242_35770461	2.19	Hspbap1	Hspb associated protein 1	24	0.95
chr2_144369068_144369473	2.19	Kat14	lysine acetyltransferase 14	271	0.47
chr6_116207685_116208163	2.18	9530062K07Rik	RIKEN cDNA 9530062K07 gene	69	0.55
chr10_4105634_4106127	2.15	Gm25515	predicted gene, 25515	1567	0.43
chr13_91179603_91179754	2.13	Gm17450	predicted gene, 17450	40774	0.15
chr13_67194563_67195091	2.13	Zfp455	zinc finger protein 455	292	0.79
chr5_72167567_72168551	2.12	Commd8	COMM domain containing 8	97	0.97
chr6_17796921_17797464	2.10	Gm26738	predicted gene, 26738	37993	0.12
chr13_109652180_109652468	2.09	Pde4d	phosphodiesterase 4D, cAMP specific	19544	0.3
chr14_105513385_105513572	2.08	Gm35909	predicted gene, 35909	4618	0.22
chr1_54762260_54762411	2.08	Ankrd44	ankyrin repeat domain 44	1393	0.4
chr6_86585065_86585561	2.08	Gm44369	predicted gene, 44369	6117	0.12
chr18_24203142_24203293	2.08	Galnt1	polypeptide N-acetylgalactosaminyltransferase 1	2127	0.36
chr17_23549519_23549705	2.07	6330415G19Rik	RIKEN cDNA 6330415G19 gene	1187	0.26
chr10_19397498_19397653	2.06	Olig3	oligodendrocyte transcription factor 3	41042	0.16
chr10_67297244_67297395	2.03	Gm49454	predicted gene, 49454	87	0.97
chr2_74136671_74137003	2.03	Gm13667	predicted gene 13667	1080	0.52
chr11_55204145_55204864	2.03	Slc36a1	solute carrier family 36 (proton/amino acid symporter), member 1	128	0.95
chr13_91223571_91224137	2.01	Atg10	autophagy related 10	105	0.96
chr14_56844651_56844806	1.99	Gm22498	predicted gene, 22498	7572	0.1
chr8_48740271_48740452	1.99	Tenm3	teneurin transmembrane protein 3	65671	0.13
chr13_74010319_74010520	1.99	Tppp	tubulin polymerization promoting protein	1000	0.3
chr2_70565058_70565237	1.98	Gad1	glutamate decarboxylase 1	1230	0.34
chr1_171109674_171109865	1.97	Cfap126	cilia and flagella associated protein 126	4149	0.12
chr3_130729801_130730783	1.95	Rpl34	ribosomal protein L34	29	0.67
chr6_140768890_140769790	1.95	Gm43925	predicted gene, 43925	15364	0.19
chr6_39423688_39423950	1.94	Gm25402	predicted gene, 25402	1400	0.3
chr9_123717480_123717856	1.94	Lztfl1	leucine zipper transcription factor-like 1	29	0.96
chr10_127107795_127107946	1.94	Os9	amplified in osteosarcoma	13245	0.07
chr12_12237057_12237208	1.94	Fam49a	family with sequence similarity 49, member A	25007	0.24
chr11_81100943_81101098	1.94	Gm11417	predicted gene 11417	28617	0.19
chr19_54114913_54115287	1.93	Gm50186	predicted gene, 50186	30541	0.18
chr7_19508089_19508456	1.93	Bloc1s3	biogenesis of lysosomal organelles complex-1, subunit 3	95	0.52
chr2_122234942_122235324	1.91	Sord	sorbitol dehydrogenase	384	0.76
chr2_163722562_163722881	1.91	Ada	adenosine deaminase	8145	0.16
chr14_62416217_62416427	1.91	Gucy1b2	guanylate cyclase 1, soluble, beta 2	38471	0.13
chr10_63653021_63653172	1.89	Ctnna3	catenin (cadherin associated protein), alpha 3	78590	0.11
chr11_49203090_49203797	1.85	Zfp62	zinc finger protein 62	42	0.96
chr13_85189229_85189512	1.85	Ccnh	cyclin H	38	0.98
chr2_94479768_94480087	1.85	Api5	apoptosis inhibitor 5	41791	0.13
chr13_113031764_113032269	1.85	Cdc20b	cell division cycle 20B	3095	0.11
chr8_39155883_39156062	1.84	Gm20948	predicted gene, 20948	45077	0.13
chr10_117675713_117675996	1.84	Cpm	carboxypeptidase M	39	0.97
chr16_91962322_91962473	1.83	Gm27773	predicted gene, 27773	18249	0.11
chr16_32645283_32645901	1.83	Tnk2	tyrosine kinase, non-receptor, 2	633	0.65
chr3_20035237_20035420	1.83	Hps3	HPS3, biogenesis of lysosomal organelles complex 2 subunit 1	13	0.98
chr17_22361319_22361509	1.83	Zfp944	zinc finger protein 944	14	0.51
chr18_53175929_53176995	1.83	Snx2	sorting nexin 2	73	0.98
chr7_142387340_142388526	1.82	Ctsd	cathepsin D	76	0.94
chr10_115315363_115316137	1.81	Gm10752	predicted gene 10752	104	0.57
chr11_110379715_110380290	1.80	Map2k6	mitogen-activated protein kinase kinase 6	19120	0.23

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Bhlhe40

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.3	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.9	2.8	GO:2000111	positive regulation of macrophage apoptotic process(GO:2000111)
0.9	1.9	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.9	2.8	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.8	2.5	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.8	2.4	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.8	2.4	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.7	2.2	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.7	2.8	GO:0009957	epidermal cell fate specification(GO:0009957)
0.7	2.0	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.7	3.4	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.6	1.7	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.5	2.6	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.5	1.5	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.5	3.4	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.5	2.4	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.5	1.9	GO:0009158	ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.5	1.4	GO:0006059	hexitol metabolic process(GO:0006059)
0.5	1.8	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.5	7.3	GO:0061462	protein localization to lysosome(GO:0061462)
0.4	2.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.4	1.3	GO:0071873	response to norepinephrine(GO:0071873)
0.4	0.8	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.4	8.2	GO:0072525	pyridine-containing compound biosynthetic process(GO:0072525)
0.4	1.2	GO:0001828	inner cell mass cellular morphogenesis(GO:0001828)
0.4	0.4	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.4	1.1	GO:0030242	pexophagy(GO:0030242)
0.4	1.5	GO:0061055	myotome development(GO:0061055)
0.4	1.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.4	3.3	GO:0050957	equilibrioception(GO:0050957)
0.4	1.1	GO:0051182	coenzyme transport(GO:0051182)
0.4	1.8	GO:0015808	L-alanine transport(GO:0015808)
0.3	1.3	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3	1.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.3	0.9	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.3	3.2	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.3	2.4	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.3	1.2	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.3	0.9	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.3	1.1	GO:0071205	protein localization to juxtaparanode region of axon(GO:0071205)
0.3	0.8	GO:1903232	melanosome assembly(GO:1903232)
0.3	0.8	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.3	2.1	GO:0043482	cellular pigment accumulation(GO:0043482)
0.3	0.5	GO:0072061	inner medullary collecting duct development(GO:0072061)
0.3	1.5	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3	2.3	GO:0006983	ER overload response(GO:0006983)
0.2	1.0	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2	1.2	GO:0010587	miRNA catabolic process(GO:0010587)
0.2	0.7	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.2	0.7	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.2	1.9	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2	0.7	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.2	0.9	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.2	1.1	GO:1902308	regulation of peptidyl-serine dephosphorylation(GO:1902308)
0.2	2.5	GO:0007097	nuclear migration(GO:0007097)
0.2	0.7	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2	0.9	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2	1.8	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.2	0.6	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.2	0.6	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.2	4.9	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.2	0.4	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.2	0.4	GO:0071336	regulation of hair follicle cell proliferation(GO:0071336)
0.2	3.4	GO:0060009	Sertoli cell development(GO:0060009)
0.2	0.8	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.2	1.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.2	1.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.2	2.4	GO:0002115	store-operated calcium entry(GO:0002115)
0.2	0.5	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.2	0.7	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.2	0.5	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.2	0.7	GO:0090148	membrane fission(GO:0090148)
0.2	1.0	GO:1904424	regulation of GTP binding(GO:1904424)
0.2	0.7	GO:0098535	de novo centriole assembly(GO:0098535)
0.2	0.5	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2	6.3	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.2	0.5	GO:0016095	polyprenol catabolic process(GO:0016095)
0.2	1.6	GO:0090161	Golgi ribbon formation(GO:0090161)
0.2	1.0	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.2	0.5	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2	0.3	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.2	0.5	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.2	0.6	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2	2.0	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.2	1.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2	0.9	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.2	2.1	GO:0046697	decidualization(GO:0046697)
0.2	0.3	GO:0060167	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) regulation of adenosine receptor signaling pathway(GO:0060167)
0.2	0.6	GO:0016198	axon choice point recognition(GO:0016198)
0.1	1.2	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.1	0.4	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1	0.4	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1	0.4	GO:0031296	B cell costimulation(GO:0031296)
0.1	0.4	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.1	0.3	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
0.1	2.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.1	0.4	GO:0033326	cerebrospinal fluid secretion(GO:0033326)
0.1	0.5	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1	0.6	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1	0.3	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.1	1.3	GO:0099514	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1	0.9	GO:0002857	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.6	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.1	0.4	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.4	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1	0.4	GO:0070827	chromatin maintenance(GO:0070827)
0.1	0.4	GO:0060166	olfactory pit development(GO:0060166)
0.1	0.1	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1	0.5	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.1	1.0	GO:0000059	protein import into nucleus, docking(GO:0000059)
0.1	0.4	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.1	0.5	GO:0006407	rRNA export from nucleus(GO:0006407)
0.1	0.6	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
0.1	0.3	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.1	0.2	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.1	0.5	GO:0043173	nucleotide salvage(GO:0043173)
0.1	0.4	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.1	0.3	GO:1903286	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1	0.7	GO:0045359	positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.1	0.7	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1	0.7	GO:0008089	anterograde axonal transport(GO:0008089)
0.1	0.7	GO:0097264	self proteolysis(GO:0097264)
0.1	0.9	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1	0.4	GO:0070126	mitochondrial translational termination(GO:0070126)
0.1	1.1	GO:0001675	acrosome assembly(GO:0001675)
0.1	0.4	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
0.1	1.1	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.1	0.9	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.1	0.5	GO:0032596	protein transport into membrane raft(GO:0032596)
0.1	1.6	GO:0030488	tRNA methylation(GO:0030488)
0.1	0.4	GO:2000852	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1	0.8	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.6	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1	1.0	GO:0060134	prepulse inhibition(GO:0060134)
0.1	0.3	GO:0097476	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.1	0.6	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.1	0.5	GO:0002317	plasma cell differentiation(GO:0002317)
0.1	0.2	GO:0022417	protein maturation by protein folding(GO:0022417)
0.1	0.3	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	0.2	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	0.3	GO:0048023	positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.1	0.2	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.1	0.2	GO:1903596	regulation of gap junction assembly(GO:1903596)
0.1	0.5	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.2	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.1	0.9	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1	1.0	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.1	0.3	GO:0060279	positive regulation of ovulation(GO:0060279)
0.1	1.0	GO:2000269	regulation of fibroblast apoptotic process(GO:2000269)
0.1	0.2	GO:0090135	actin filament branching(GO:0090135)
0.1	0.6	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.1	1.7	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1	1.2	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
0.1	0.1	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.1	0.7	GO:1901673	regulation of mitotic spindle assembly(GO:1901673)
0.1	0.2	GO:0030035	microspike assembly(GO:0030035)
0.1	1.1	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.1	0.3	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.1	0.9	GO:0042407	cristae formation(GO:0042407)
0.1	0.1	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1	1.5	GO:0000281	mitotic cytokinesis(GO:0000281)
0.1	1.1	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	0.2	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.1	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.1	0.1	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.1	0.2	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.1	0.4	GO:0060052	neurofilament cytoskeleton organization(GO:0060052)
0.1	1.8	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.1	0.2	GO:1901977	negative regulation of cell cycle checkpoint(GO:1901977)
0.1	0.2	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.1	0.1	GO:0010918	positive regulation of mitochondrial membrane potential(GO:0010918)
0.1	0.5	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.1	3.2	GO:0045454	cell redox homeostasis(GO:0045454)
0.1	0.3	GO:0042256	mature ribosome assembly(GO:0042256)
0.1	0.2	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.1	0.3	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.1	0.4	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.2	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.1	0.2	GO:0009436	glyoxylate catabolic process(GO:0009436) glyoxylate metabolic process(GO:0046487)
0.1	0.4	GO:0033182	regulation of histone ubiquitination(GO:0033182)
0.1	0.2	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.1	0.1	GO:0018992	germ-line sex determination(GO:0018992)
0.1	0.2	GO:0038094	Fc-gamma receptor signaling pathway(GO:0038094)
0.1	0.2	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.1	0.6	GO:0035879	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1	0.1	GO:0019448	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1	0.2	GO:0036490	regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492)
0.1	0.1	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.1	0.8	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1	0.1	GO:0045794	negative regulation of cell volume(GO:0045794)
0.1	0.1	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.1	0.2	GO:0032438	melanosome organization(GO:0032438)
0.1	0.1	GO:0009826	unidimensional cell growth(GO:0009826)
0.1	0.2	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	0.2	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1	0.3	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.4	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:0090261	positive regulation of inclusion body assembly(GO:0090261)
0.0	0.0	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.0	0.3	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.0	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.4	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.1	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.5	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	0.2	GO:0003344	pericardium morphogenesis(GO:0003344)
0.0	0.3	GO:0045217	cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0033861	negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.0	0.1	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.0	0.0	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.3	GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0	0.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.8	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.0	0.8	GO:0050901	leukocyte tethering or rolling(GO:0050901)
0.0	0.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0046959	habituation(GO:0046959)
0.0	0.1	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.5	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0	0.1	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0	0.1	GO:0035247	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.2	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.5	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.3	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.2	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.5	GO:0030728	ovulation(GO:0030728)
0.0	0.4	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.2	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.0	0.5	GO:0031571	mitotic G1 DNA damage checkpoint(GO:0031571)
0.0	0.1	GO:1902065	response to L-glutamate(GO:1902065)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.2	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.1	GO:0052203	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	2.1	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.1	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.2	GO:0086103	G-protein coupled receptor signaling pathway involved in heart process(GO:0086103)
0.0	0.2	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.4	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	1.4	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.2	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0072262	metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.0	0.2	GO:0006265	DNA topological change(GO:0006265)
0.0	0.0	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	1.1	GO:0000245	spliceosomal complex assembly(GO:0000245)
0.0	0.1	GO:0033566	gamma-tubulin complex localization(GO:0033566)
0.0	0.3	GO:0034375	high-density lipoprotein particle remodeling(GO:0034375)
0.0	0.4	GO:0032310	prostaglandin secretion(GO:0032310)
0.0	1.7	GO:0030433	ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0	0.2	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.0	0.2	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.3	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.2	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.2	GO:0021756	striatum development(GO:0021756)
0.0	0.3	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.5	GO:0050860	negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	0.1	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.2	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.2	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	1.0	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.5	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.3	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.1	GO:0099558	maintenance of synapse structure(GO:0099558)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.0	GO:0090091	positive regulation of extracellular matrix disassembly(GO:0090091)
0.0	0.1	GO:0007220	Notch receptor processing(GO:0007220)
0.0	1.1	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.1	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0	0.1	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.0	0.1	GO:0070340	detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.1	GO:1902218	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.1	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
0.0	0.2	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.0	0.2	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.0	0.0	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.0	GO:0035524	proline transmembrane transport(GO:0035524)
0.0	0.1	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.0	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.0	0.2	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.4	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
0.0	0.0	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.2	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.0	GO:1904526	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0	1.2	GO:0000045	autophagosome assembly(GO:0000045)
0.0	0.1	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.0	0.0	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.0	GO:0035995	detection of muscle stretch(GO:0035995)
0.0	0.0	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.0	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.1	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	1.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.1	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	0.0	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.0	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.1	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.0	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0	0.5	GO:0042417	dopamine metabolic process(GO:0042417)
0.0	0.4	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.2	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.0	GO:1901843	positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0	0.2	GO:0042492	gamma-delta T cell differentiation(GO:0042492)
0.0	0.2	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.4	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.1	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	1.9	GO:0007286	spermatid development(GO:0007286)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.0	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.0	0.0	GO:0002461	tolerance induction dependent upon immune response(GO:0002461)
0.0	0.1	GO:0033572	transferrin transport(GO:0033572)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.2	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0033700	phospholipid efflux(GO:0033700)
0.0	0.0	GO:0044597	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0043465	regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.0	0.4	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0030007	cellular potassium ion homeostasis(GO:0030007)
0.0	0.0	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.2	GO:0003417	growth plate cartilage development(GO:0003417)
0.0	0.0	GO:0003011	diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011)
0.0	0.1	GO:0034047	regulation of protein phosphatase type 2A activity(GO:0034047)
0.0	0.4	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.5	GO:0046785	microtubule polymerization(GO:0046785)
0.0	0.1	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.0	GO:0042635	positive regulation of hair cycle(GO:0042635)
0.0	0.0	GO:0060618	nipple development(GO:0060618)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.0	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.0	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.0	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0	0.1	GO:0044872	lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0	0.4	GO:0051155	positive regulation of striated muscle cell differentiation(GO:0051155)
0.0	0.0	GO:0035799	ureter maturation(GO:0035799)
0.0	0.7	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.2	GO:0061512	protein localization to cilium(GO:0061512)
0.0	1.0	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.0	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.0	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.0	0.0	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.4	GO:0071427	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.2	GO:0048821	erythrocyte development(GO:0048821)
0.0	0.0	GO:0008355	olfactory learning(GO:0008355)
0.0	0.1	GO:0044406	adhesion of symbiont to host(GO:0044406)
0.0	0.0	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.0	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.0	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.0	0.0	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0006777	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0002838	negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.0	0.0	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.0	GO:2000020	positive regulation of male gonad development(GO:2000020)
0.0	0.0	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.1	GO:0006972	hyperosmotic response(GO:0006972)
0.0	0.0	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.0	0.0	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.0	GO:0090272	negative regulation of fibroblast growth factor production(GO:0090272)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.0	GO:0048245	eosinophil chemotaxis(GO:0048245)
0.0	0.1	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0	0.4	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.0	GO:0048290	isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0	0.2	GO:0033344	cholesterol efflux(GO:0033344)
0.0	0.0	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.3	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.0	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533)
0.0	0.0	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.9	GO:0006261	DNA-dependent DNA replication(GO:0006261)
0.0	0.0	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.0	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.0	GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901) positive regulation of G0 to G1 transition(GO:0070318)
0.0	0.1	GO:2001223	negative regulation of neuron migration(GO:2001223)
0.0	0.0	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	3.3	GO:0005879	axonemal microtubule(GO:0005879)
1.0	3.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.9	3.6	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.8	3.2	GO:0097422	tubular endosome(GO:0097422)
0.8	2.4	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.8	2.3	GO:0031084	BLOC-2 complex(GO:0031084)
0.7	2.6	GO:0033553	rDNA heterochromatin(GO:0033553)
0.6	3.4	GO:0071986	Ragulator complex(GO:0071986)
0.6	2.8	GO:0016461	unconventional myosin complex(GO:0016461)
0.6	2.8	GO:0044294	dendritic growth cone(GO:0044294)
0.5	4.3	GO:0042788	polysomal ribosome(GO:0042788)
0.5	2.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.5	2.8	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.4	4.7	GO:0070938	contractile ring(GO:0070938)
0.4	3.5	GO:0005869	dynactin complex(GO:0005869)
0.4	1.1	GO:0097454	Schwann cell microvillus(GO:0097454)
0.3	2.6	GO:0000243	commitment complex(GO:0000243)
0.3	1.8	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.3	1.4	GO:0043202	lysosomal lumen(GO:0043202)
0.3	1.1	GO:1990131	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3	1.9	GO:0030008	TRAPP complex(GO:0030008)
0.3	3.2	GO:0005685	U1 snRNP(GO:0005685)
0.3	1.0	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.2	0.7	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.2	0.8	GO:0089701	U2AF(GO:0089701)
0.2	1.0	GO:0030896	checkpoint clamp complex(GO:0030896)
0.2	3.0	GO:0031082	BLOC complex(GO:0031082)
0.2	1.6	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.2	0.8	GO:0061617	MICOS complex(GO:0061617)
0.2	0.5	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.9	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.1	0.9	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1	0.7	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.8	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	0.6	GO:0033503	HULC complex(GO:0033503)
0.1	0.4	GO:0097413	Lewy body(GO:0097413)
0.1	1.8	GO:0030904	retromer complex(GO:0030904)
0.1	1.9	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	0.9	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.4	GO:1990246	uniplex complex(GO:1990246)
0.1	0.8	GO:0033263	CORVET complex(GO:0033263)
0.1	0.6	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.1	0.8	GO:0030991	intraciliary transport particle A(GO:0030991)
0.1	1.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.4	GO:0033269	internode region of axon(GO:0033269)
0.1	0.2	GO:0005687	U4 snRNP(GO:0005687)
0.1	0.3	GO:0043511	inhibin complex(GO:0043511)
0.1	0.3	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.1	0.4	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.1	2.9	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	0.6	GO:0032982	myosin filament(GO:0032982)
0.1	0.3	GO:0042585	germinal vesicle(GO:0042585)
0.1	0.6	GO:0042382	paraspeckles(GO:0042382)
0.1	2.5	GO:0016235	aggresome(GO:0016235)
0.1	1.5	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.4	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	0.4	GO:0016589	NURF complex(GO:0016589)
0.1	0.9	GO:0032433	filopodium tip(GO:0032433)
0.1	2.4	GO:0032040	small-subunit processome(GO:0032040)
0.1	0.2	GO:0032010	phagolysosome(GO:0032010)
0.1	0.4	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1	0.1	GO:0031088	platelet dense granule membrane(GO:0031088) platelet dense granule(GO:0042827)
0.1	0.3	GO:0061574	ASAP complex(GO:0061574)
0.1	0.2	GO:0005594	collagen type IX trimer(GO:0005594)
0.1	0.4	GO:0000439	core TFIIH complex(GO:0000439)
0.1	0.3	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.1	0.5	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	1.2	GO:1902711	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1	0.3	GO:0000938	GARP complex(GO:0000938)
0.1	1.0	GO:0000145	exocyst(GO:0000145)
0.1	1.0	GO:0097440	apical dendrite(GO:0097440)
0.1	1.2	GO:0002080	acrosomal membrane(GO:0002080)
0.1	0.1	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1	0.7	GO:0034704	calcium channel complex(GO:0034704)
0.1	0.7	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.3	GO:0030686	90S preribosome(GO:0030686)
0.1	0.7	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1	0.6	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1	0.4	GO:0070187	telosome(GO:0070187)
0.1	0.3	GO:0031415	NatA complex(GO:0031415)
0.1	2.3	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.7	GO:0016460	myosin II complex(GO:0016460)
0.0	0.6	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.5	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.7	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.0	0.4	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	1.8	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.6	GO:0060077	inhibitory synapse(GO:0060077)
0.0	4.9	GO:0030426	growth cone(GO:0030426)
0.0	1.0	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.7	GO:0031941	filamentous actin(GO:0031941)
0.0	0.3	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	3.0	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.9	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	1.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	1.8	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.5	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	1.8	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	2.2	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.3	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.1	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0	0.4	GO:0035371	microtubule plus-end(GO:0035371)
0.0	1.1	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.4	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	1.1	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.2	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	1.4	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.1	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.0	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:1990923	PET complex(GO:1990923)
0.0	0.0	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.0	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	3.4	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:0031209	SCAR complex(GO:0031209)
0.0	0.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0090543	Flemming body(GO:0090543)
0.0	4.7	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	1.8	GO:0031225	anchored component of membrane(GO:0031225)
0.0	1.1	GO:0005774	vacuolar membrane(GO:0005774)
0.0	0.0	GO:0044308	axonal spine(GO:0044308)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.0	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.0	GO:0035838	growing cell tip(GO:0035838)
0.0	0.8	GO:0070469	respiratory chain(GO:0070469)
0.0	1.1	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.0	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.0	GO:0030684	preribosome(GO:0030684)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.0	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.0	0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.8	GO:0005119	smoothened binding(GO:0005119)
0.9	2.6	GO:0043398	HLH domain binding(GO:0043398)
0.8	3.2	GO:0030619	U1 snRNA binding(GO:0030619)
0.8	2.4	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.8	2.3	GO:0019776	Atg8 ligase activity(GO:0019776)
0.7	2.9	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.6	2.5	GO:1904288	BAT3 complex binding(GO:1904288)
0.6	2.4	GO:0030984	kininogen binding(GO:0030984)
0.6	4.3	GO:0008097	5S rRNA binding(GO:0008097)
0.6	1.8	GO:1990460	leptin receptor binding(GO:1990460)
0.6	4.5	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.6	2.8	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.5	1.6	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.5	1.9	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.4	6.6	GO:0030955	potassium ion binding(GO:0030955)
0.4	1.3	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.4	12.7	GO:0050699	WW domain binding(GO:0050699)
0.4	1.2	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.4	1.6	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.4	2.2	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021)
0.3	1.3	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.3	1.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.3	0.9	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.3	1.9	GO:0016936	galactoside binding(GO:0016936)
0.3	1.2	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3	0.9	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3	0.9	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.3	3.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.3	0.8	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.3	1.0	GO:0051185	coenzyme transporter activity(GO:0051185)
0.3	0.8	GO:0043199	sulfate binding(GO:0043199)
0.3	1.0	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.2	1.7	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.2	3.0	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.2	0.7	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.2	0.9	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	1.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.2	1.0	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2	1.0	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.2	0.2	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.2	0.9	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2	1.2	GO:0103116	alpha-D-galactofuranose transporter activity(GO:0103116)
0.2	4.3	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.2	0.7	GO:1990254	keratin filament binding(GO:1990254)
0.2	0.5	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2	0.5	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.2	0.5	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.2	1.8	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.2	0.2	GO:0009019	tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1	0.4	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	2.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1	0.4	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.4	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.3	GO:0080084	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.1	0.4	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.6	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1	0.5	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1	0.6	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	9.8	GO:0008565	protein transporter activity(GO:0008565)
0.1	0.3	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.1	1.4	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.1	1.6	GO:0043274	phospholipase binding(GO:0043274)
0.1	0.4	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	2.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.6	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.4	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	1.2	GO:0050811	GABA receptor binding(GO:0050811)
0.1	1.3	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.1	0.4	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.1	0.7	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.1	0.3	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.3	GO:0004849	uridine kinase activity(GO:0004849)
0.1	1.7	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.3	GO:0015288	porin activity(GO:0015288)
0.1	0.3	GO:0071253	connexin binding(GO:0071253)
0.1	0.4	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.3	GO:0038064	collagen receptor activity(GO:0038064)
0.1	0.3	GO:0034711	inhibin binding(GO:0034711)
0.1	0.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	2.5	GO:0000049	tRNA binding(GO:0000049)
0.1	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1	0.2	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1	0.5	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.3	GO:0031720	haptoglobin binding(GO:0031720)
0.1	3.9	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1	1.0	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	0.2	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.1	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	0.3	GO:0005131	growth hormone receptor binding(GO:0005131)
0.1	0.7	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	1.6	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	0.3	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.2	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.1	1.0	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1	0.2	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.1	0.2	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1	0.5	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.1	0.3	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	1.3	GO:0098519	nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.2	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546)
0.0	0.8	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.1	GO:0051373	FATZ binding(GO:0051373)
0.0	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	1.6	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.6	GO:0032183	SUMO binding(GO:0032183)
0.0	0.2	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.3	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.0	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.3	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.4	GO:0048185	activin binding(GO:0048185)
0.0	0.5	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.2	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.4	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.6	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	1.0	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	1.7	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.2	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	2.0	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.2	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.2	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.6	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.0	0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.2	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.2	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.4	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	1.0	GO:0061650	ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	1.1	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.7	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.2	GO:0035473	lipase binding(GO:0035473)
0.0	0.2	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.3	GO:0035240	dopamine binding(GO:0035240)
0.0	0.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.2	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	2.5	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	1.4	GO:0051287	NAD binding(GO:0051287)
0.0	0.2	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.0	6.4	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	1.6	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.1	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.1	GO:0034511	U3 snoRNA binding(GO:0034511)
0.0	0.4	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.2	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	4.4	GO:0035091	phosphatidylinositol binding(GO:0035091)
0.0	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.1	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.1	GO:0015205	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.4	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	1.3	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.3	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.6	GO:0035254	glutamate receptor binding(GO:0035254)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.6	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.0	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0	0.0	GO:0000182	rDNA binding(GO:0000182)
0.0	0.9	GO:0044823	integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.1	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.9	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.3	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	1.2	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.2	GO:0034784	pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0	0.1	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.4	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.2	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
0.0	0.9	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.0	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.2	GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.4	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0	0.0	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.5	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0	0.6	GO:0005109	frizzled binding(GO:0005109)
0.0	0.5	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.6	GO:0019209	kinase activator activity(GO:0019209)
0.0	0.4	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	1.1	GO:0016273	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0	0.1	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.3	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.6	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442)
0.0	0.0	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.0	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.0	GO:0052832	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.0	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.0	GO:1901611	phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0019767	IgE receptor activity(GO:0019767)
0.0	0.1	GO:0016594	glycine binding(GO:0016594)
0.0	0.0	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.4	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.3	GO:0043022	ribosome binding(GO:0043022)
0.0	0.0	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.0	GO:0004096	catalase activity(GO:0004096)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	1.3	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.1	2.9	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	2.9	PID ATM PATHWAY	ATM pathway
0.1	0.8	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	2.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	2.8	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	1.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	2.4	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.1	1.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	2.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	1.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.1	1.5	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	3.1	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	2.6	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.2	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	1.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.4	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.9	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.4	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.5	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.9	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.2	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.9	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.3	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.3	PID ATR PATHWAY	ATR signaling pathway
0.0	0.2	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.2	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.2	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.4	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	0.2	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.2	1.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.2	2.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.2	1.9	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.2	2.6	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2	7.6	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.2	3.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.1	1.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	2.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.1	1.4	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	1.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	3.0	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	2.8	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	2.5	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	1.0	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1	0.9	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	0.8	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.1	2.0	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.1	0.9	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	0.9	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.1	1.1	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	1.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	1.7	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	2.1	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	1.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.7	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.1	4.2	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	0.4	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.1	1.0	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	0.8	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	0.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	5.4	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	1.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	1.0	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	2.2	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.7	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.4	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.0	3.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.3	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	1.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	2.5	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.1	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.7	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	1.0	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.1	REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA	Genes involved in Processing of Capped Intronless Pre-mRNA
0.0	0.7	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.3	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	1.7	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.2	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME G PROTEIN BETA GAMMA SIGNALLING	Genes involved in G-protein beta:gamma signalling
0.0	0.1	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.0	REACTOME GABA RECEPTOR ACTIVATION	Genes involved in GABA receptor activation
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.5	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.6	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.4	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.5	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling

Results for Bhlhe40

Z-value: 1.82

Motif logo

Transcription factors associated with Bhlhe40

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Bhlhe40 motif across conditions

Conditions sorted by the z-value of the Bhlhe40 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Bhlhe40

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: